Chi Keung Lam - Publications

Affiliations: 
Stanford University Medical School 

22/49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lazzarino M, Zanetti M, Chen SN, Gao S, Peña B, Lam CK, Wu JC, Taylor MRG, Mestroni L, Sbaizero O. Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations. International Journal of Molecular Sciences. 25. PMID 38474188 DOI: 10.3390/ijms25052942  0.483
2024 Gao S, He L, Lam CK, Taylor MRG, Mestroni L, Lombardi R, Chen SN. Filamin C Deficiency Impairs Sarcomere Stability and Activates Focal Adhesion Kinase through PDGFRA Signaling in Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cells. 13. PMID 38334670 DOI: 10.3390/cells13030278  0.429
2023 Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA, Yang H, Abilez OJ, Lyu X, Narayan SM, Mestroni L, et al. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nature Biomedical Engineering. PMID 38012305 DOI: 10.1038/s41551-023-01134-x  0.743
2023 Ramachandran A, Livingston CE, Vite A, Corbin EA, Bennett AI, Turner KT, Lee BW, Lam CK, Wu JC, Margulies KB. Biomechanical Impact of Pathogenic MYBPC3 Truncation Variant Revealed by Dynamically Tuning In Vitro Afterload. Journal of Cardiovascular Translational Research. PMID 36877449 DOI: 10.1007/s12265-022-10348-4  0.468
2022 Wang YJ, Zhang X, Lam CK, Guo H, Wang C, Zhang S, Wu JC, Snyder M, Li J. Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome. Cell Systems. PMID 36167075 DOI: 10.1016/j.cels.2022.09.001  0.44
2022 Chen SN, Lam CK, Wan YW, Gao S, Malak OA, Zhao SR, Lombardi R, Ambardekar AV, Bristow MR, Cleveland J, Gigli M, Sinagra G, Graw S, Taylor MRG, Wu JC, et al. Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy. Science Advances. 8: eabk0052. PMID 35196083 DOI: 10.1126/sciadv.abk0052  0.604
2021 Roberts RJ, Hallee L, Lam CK. The Potential of Hsp90 in Targeting Pathological Pathways in Cardiac Diseases. Journal of Personalized Medicine. 11. PMID 34945845 DOI: 10.3390/jpm11121373  0.408
2021 Sen S, Hallee L, Lam CK. The Potential of Gamma Secretase as a Therapeutic Target for Cardiac Diseases. Journal of Personalized Medicine. 11. PMID 34945766 DOI: 10.3390/jpm11121294  0.643
2021 Lam CK, Wu JC. Clinical Trial in a Dish: Using Patient-Derived Induced Pluripotent Stem Cells to Identify Risks of Drug-Induced Cardiotoxicity. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314695. PMID 33472401 DOI: 10.1161/ATVBAHA.120.314695  0.493
2020 Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, et al. Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Cell Reports. 32: 107925. PMID 32697997 DOI: 10.1016/J.Celrep.2020.107925  0.574
2020 Rhee JW, Yi H, Thomas D, Lam CK, Belbachir N, Tian L, Qin X, Malisa J, Lau E, Paik DT, Kim Y, Choi BS, Sayed N, Sallam K, Liao R, et al. Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cell Reports. 32: 107886. PMID 32668256 DOI: 10.1016/J.Celrep.2020.107886  0.763
2019 Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X  0.725
2019 Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. European Heart Journal. PMID 31219556 DOI: 10.1093/Eurheartj/Ehz326  0.782
2019 Lam CK, Tian L, Belbachir N, Shrestha R, Ma N, Kitani T, Rhee JW, Wnorowski A, Wu JC. Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. PMID 31079550 DOI: 10.1161/Circresaha.118.314202  0.749
2019 Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. PMID 30880024 DOI: 10.1016/J.Stem.2019.02.015  0.75
2019 Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Human Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Breast Cancer Patients. Circulation. PMID 30866650 DOI: 10.1161/Circulationaha.118.037357  0.764
2018 Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, et al. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation. PMID 30586709 DOI: 10.1161/Circulationaha.118.034624  0.742
2018 Lam CK, Wu JC. Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come? European Heart Journal. PMID 30010924 DOI: 10.1093/Eurheartj/Ehy388  0.486
2018 Garg P, Oikonomopoulos A, Chen H, Li Y, Lam CK, Sallam K, Perez M, Lux RL, Sanguinetti MC, Wu JC. Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant. Journal of the American College of Cardiology. 72: 62-75. PMID 29957233 DOI: 10.1016/J.Jacc.2018.04.041  0.762
2018 Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Circulation. PMID 29914921 DOI: 10.1161/Circulationaha.117.032273  0.78
2018 Liu GS, Gardner G, Adly G, Jiang M, Cai WF, Lam CK, Alogaili F, Robbins N, Rubinstein J, Kranias EG. A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy. Journal of Cellular and Molecular Medicine. PMID 29761889 DOI: 10.1111/Jcmm.13665  0.335
2016 Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, ... ... Lam CK, et al. Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome. Journal of the American College of Cardiology. 68: 2086-2096. PMID 27810048 DOI: 10.1016/J.Jacc.2016.07.779  0.703
Low-probability matches (unlikely to be authored by this person)
2017 Liu GS, Zhu H, Cai WF, Wang X, Jiang M, Essandoh K, Vafiadaki E, Haghighi K, Lam CK, Gardner G, Adly G, Nicolaou P, Sanoudou D, Liang Q, Rubinstein J, et al. Regulation of BECN1-Mediated Autophagy by HSPB6: Insights from A Human HSPB6(S10F) Mutant. Autophagy. 1-56. PMID 29157081 DOI: 10.1080/15548627.2017.1392420  0.3
2015 Liu GS, Morales A, Vafiadaki E, Lam CK, Cai WF, Haghighi K, Adly G, Hershberger RE, Kranias EG. A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia. Cardiovascular Research. 107: 164-74. PMID 25852082 DOI: 10.1093/Cvr/Cvv127  0.274
2011 Han P, Cai W, Wang Y, Lam CK, Arvanitis DA, Singh VP, Chen S, Zhang H, Zhang R, Cheng H, Kranias EG. Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1588-95. PMID 21742996 DOI: 10.1152/Ajpheart.01153.2010  0.262
2015 Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, et al. Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. Journal of Molecular and Cellular Cardiology. PMID 26455482 DOI: 10.1016/J.Yjmcc.2015.10.004  0.249
2013 Lam CK, Zhao W, Cai W, Vafiadaki E, Florea SM, Ren X, Liu Y, Robbins N, Zhang Z, Zhou X, Jiang M, Rubinstein J, Jones WK, Kranias EG. Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90. Circulation Research. 112: 79-89. PMID 22982986 DOI: 10.1161/Circresaha.112.279935  0.248
2009 Zhao W, Waggoner JR, Zhang ZG, Lam CK, Han P, Qian J, Schroder PM, Mitton B, Kontrogianni-Konstantopoulos A, Robia SL, Kranias EG. The anti-apoptotic protein HAX-1 is a regulator of cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 106: 20776-81. PMID 19920172 DOI: 10.1073/Pnas.0906998106  0.239
2017 Bidwell PA, Liu GS, Nagarajan N, Lam CK, Haghighi K, Gardner G, Cai WF, Zhao W, Mugge L, Vafiadaki E, Sanoudou D, Rubinstein J, Lebeche D, Hajjar R, Sadoshima J, et al. HAX-1 regulates SERCA2a oxidation and degradation. Journal of Molecular and Cellular Cardiology. PMID 29169992 DOI: 10.1016/J.Yjmcc.2017.11.014  0.237
2015 Lam CK, Zhao W, Liu GS, Cai WF, Gardner G, Adly G, Kranias EG. HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 26553996 DOI: 10.1073/Pnas.1508760112  0.221
2011 Wang HS, Arvanitis DA, Dong M, Niklewski PJ, Zhao W, Lam CK, Kranias EG, Sanoudou D. SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts. Physiological Genomics. 43: 357-64. PMID 21266500 DOI: 10.1152/Physiolgenomics.00032.2010  0.213
2015 Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility. European Journal of Heart Failure. 17: 782-93. PMID 26177627 DOI: 10.1002/Ejhf.323  0.201
2011 Qian J, Vafiadaki E, Florea SM, Singh VP, Song W, Lam CK, Wang Y, Yuan Q, Pritchard TJ, Cai W, Haghighi K, Rodriguez P, Wang HS, Sanoudou D, Fan GC, et al. Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling. Circulation Research. 108: 1429-38. PMID 21493896 DOI: 10.1161/Circresaha.110.237644  0.188
2011 Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. The Journal of Clinical Investigation. 121: 1044-52. PMID 21285509 DOI: 10.1172/Jci43844  0.112
2023 Pak WLW, Chan KL, Chan Z, Law WP, Wong YH, Lam CK, Wong SHS. Pet-related Neisseria zoodegmatis peritonitis in a patient on automated peritoneal dialysis. Nephrology (Carlton, Vic.). PMID 36706740 DOI: 10.1111/nep.14145  0.084
2019 Pak WLW, Chan KL, Chan Z, Law WP, Wong YH, Lam CK, Wong SHS. Acetazolamide toxicity and dosing in dialysis patients. Nephrology (Carlton, Vic.). PMID 31478276 DOI: 10.1111/nep.13654  0.077
2020 Pak WLW, Chan KL, Chan Z, Law WP, Wong YH, Lam CK, Wong SHS. A rare case of false-negative: Limitations of nucleic acid amplification tests in diagnosing tuberculous peritonitis in peritoneal dialysis patients. Nephrology (Carlton, Vic.). PMID 32203985 DOI: 10.1111/nep.13711  0.074
2022 Chiou SY, Clarke E, Lam C, Harvey T, Nightingale TE. Effects of Arm-Crank Exercise on Fitness and Health in Adults With Chronic Spinal Cord Injury: A Systematic Review. Frontiers in Physiology. 13: 831372. PMID 35392374 DOI: 10.3389/fphys.2022.831372  0.073
2017 Yin G, Lam CK, Shi H. Bayesian Randomized Clinical Trials: From Fixed to Adaptive Design. Contemporary Clinical Trials. PMID 28455232 DOI: 10.1016/J.Cct.2017.04.010  0.064
2022 Pak WLW, Chan KL, Chan Z, Wong YH, Law WP, Lam CK, Sunny Wong SH. Device-assisted continuous ambulatory peritoneal dialysis: A single-centre experience. Peritoneal Dialysis International : Journal of the International Society For Peritoneal Dialysis. 8968608221085430. PMID 35318867 DOI: 10.1177/08968608221085430  0.063
2009 Plant L, Lam C, Conway PL, O'Riordan K. Gastrointestinal microbial community shifts observed following oral administration of a Lactobacillus fermentum strain to mice. Fems Microbiology Ecology. 43: 133-40. PMID 19719673 DOI: 10.1111/j.1574-6941.2003.tb01052.x  0.051
2004 Zhu L, Lam CK, Chow LW. Sentinel lymph node biopsy or detection of micrometastasis in bone marrow: which might be an alternative to axillary lymph node dissection in breast cancer patients? Asian Journal of Surgery / Asian Surgical Association. 27: 279-83. PMID 15564179 DOI: 10.1016/S1015-9584(09)60051-8  0.044
2020 Cai W, Sun Y, Peng K, Kwok H, Lei L, Wu S, Lam CK, Li L, Gao Y. Physical-Activity-Related Injuries and Risk Factors among Secondary School Students in Hong Kong. International Journal of Environmental Research and Public Health. 17. PMID 31991589 DOI: 10.3390/ijerph17030747  0.042
2014 Chapman JR, Lam CK. Transplantation: to accept, or not to accept-that is the question. Nature Reviews. Nephrology. 10: 551-3. PMID 25201140 DOI: 10.1038/nrneph.2014.161  0.038
2003 Ho P, Law WL, Chan SC, Lam CK, Chu KW. Functional outcome following low anterior resection with total mesorectal excision in the elderly. International Journal of Colorectal Disease. 18: 230-3. PMID 12673488 DOI: 10.1007/s00384-002-0442-3  0.035
2017 Ip DK, Lau EH, So HC, Xiao J, Lam CK, Fang VJ, Tam YH, Leung GM, Cowling BJ. A Smart Card-Based Electronic School Absenteeism System for Influenza-Like Illness Surveillance in Hong Kong: Design, Implementation, and Feasibility Assessment. Jmir Public Health and Surveillance. 3: e67. PMID 28986338 DOI: 10.2196/publichealth.6810  0.032
2022 Yu S, Gao Y, Wang A, Sun Y, Wang J, Kwok HHM, Wu S, Lam CK, Tao ED, Jiao JJ, Fong SSM, Xie Y, Zhang D, Baker JS. Effectiveness of an adapted physical activity intervention for weight management in adolescents with intellectual disability: A randomized controlled trial. Pediatric Obesity. e12882. PMID 35014215 DOI: 10.1111/ijpo.12882  0.026
2021 Pak WLW, Chan KL, Chan Z, Law WP, Wong YH, Lam CK, Wong SHS. Salmonella Wandsworth peritoneal dialysis-related peritonitis following persistent infection: A case report with a review of literature. Nephrology (Carlton, Vic.). PMID 34766693 DOI: 10.1111/nep.13994  0.022
2003 Lai CW, Lam CK, Lee HK, Mak TC, Wong HN. Synthesis and studies of 1,4,5,8,9,12,13,16-octamethoxytetraphenylene. Organic Letters. 5: 823-6. PMID 12633081 DOI: 10.1021/Ol020253S  0.021
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