| Year |
Citation |
Score |
| 2024 |
Hernandez-Hernandez G, O'Dwyer SC, Yang PC, Matsumoto C, Tieu M, Fong Z, Lewis TJ, Santana LF, Clancy CE. A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle. Elife. 12. PMID 38335126 DOI: 10.7554/eLife.90604 |
0.332 |
|
| 2023 |
Sanders KM, Santana LF, Baker SA. Interstitial cells of Cajal - pacemakers of the gastrointestinal tract. The Journal of Physiology. PMID 37997170 DOI: 10.1113/JP284745 |
0.373 |
|
| 2023 |
Santana L, Matsumoto C, O'Dwyer S, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, Sato D, Clancy C, Vierra N, Trimmer J. The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes. Research Square. PMID 37502980 DOI: 10.21203/rs.3.rs-3136085/v1 |
0.326 |
|
| 2023 |
Matsumoto C, O'Dwyer SC, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, Sato D, Clancy CE, Vierra NC, Trimmer JS, Santana LF. The formation of K 2.1 macro-clusters is required for sex-specific differences in L-type Ca 1.2 clustering and function in arterial myocytes. Biorxiv : the Preprint Server For Biology. PMID 37425816 DOI: 10.1101/2023.06.27.546725 |
0.324 |
|
| 2023 |
Fong Z, Lall A, Mullins ND, Santana LF, Hollywood MA, Thornbury KD, Sergeant GP. Blockade of Kv7 channels reverses the inhibitory effects of EPAC activation on purinergic contractions of the murine detrusor. Basic & Clinical Pharmacology & Toxicology. PMID 37125918 DOI: 10.1111/bcpt.13881 |
0.416 |
|
| 2022 |
Manning D, Santana LF. Regulating voltage-gated ion channels with nanobodies. Nature Communications. 13: 7557. PMID 36494383 DOI: 10.1038/s41467-022-35027-5 |
0.41 |
|
| 2022 |
Guarina L, Moghbel AN, Pourhosseinzadeh MS, Cudmore RH, Sato D, Clancy CE, Santana LF. Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling. The Journal of General Physiology. 154. PMID 35482009 DOI: 10.1085/jgp.202012613 |
0.366 |
|
| 2021 |
Dixon RE, Navedo MF, Binder MD, Santana LF. Mechanisms and Physiological Implications of Cooperative Gating of Ion Channels Clusters. Physiological Reviews. PMID 34927454 DOI: 10.1152/physrev.00022.2021 |
0.592 |
|
| 2021 |
Vierra NC, O'Dwyer SC, Matsumoto C, Santana LF, Trimmer JS. Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca channels at ER-PM junctions. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34750263 DOI: 10.1073/pnas.2110094118 |
0.469 |
|
| 2020 |
Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, et al. AKAP5 complex facilitates purinergic modulation of vascular L-type Ca channel Ca1.2. Nature Communications. 11: 5303. PMID 33082339 DOI: 10.1038/s41467-020-18947-y |
0.365 |
|
| 2020 |
O'Dwyer SC, Navedo MF, Santana LF. Maladaptive response of arterial myocytes to chronic exposure to Ca channel blockers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32680960 DOI: 10.1073/Pnas.2011909117 |
0.35 |
|
| 2020 |
Nieves-Cintron M, Santana LF, Navedo MF. TRPML1ng on sparks. Science Signaling. 13. PMID 32576679 DOI: 10.1126/Scisignal.Abc0993 |
0.387 |
|
| 2020 |
O'Dwyer SC, Palacio S, Matsumoto C, Guarina L, Klug NR, Tajada S, Rosati B, McKinnon D, Trimmer JS, Santana LF. Kv2.1 channels play opposing roles in regulating membrane potential, Ca channel function, and myogenic tone in arterial smooth muscle. Proceedings of the National Academy of Sciences of the United States of America. 117: 3858-3866. PMID 32015129 DOI: 10.1073/pnas.1917879117 |
0.44 |
|
| 2019 |
Vierra NC, Kirmiz M, van der List D, Santana LF, Trimmer JS. Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons. Elife. 8. PMID 31663850 DOI: 10.7554/eLife.49953 |
0.419 |
|
| 2019 |
Sato D, Hernández-Hernández G, Matsumoto C, Tajada S, Moreno CM, Dixon RE, O'Dwyer S, Navedo MF, Trimmer JS, Clancy CE, Binder MD, Santana LF. A stochastic model of ion channel cluster formation in the plasma membrane. The Journal of General Physiology. PMID 31371391 DOI: 10.1085/Jgp.201912327 |
0.549 |
|
| 2019 |
Syed AU, Reddy GR, Ghosh D, Prada MP, Nystoriak MA, Morotti S, Grandi E, Sirish P, Chiamvimonvat N, Hell JW, Santana LF, Xiang YK, Nieves-Cintrón M, Navedo MF. Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia. The Journal of Clinical Investigation. 130. PMID 31162142 DOI: 10.1172/Jci124705 |
0.334 |
|
| 2018 |
De La Mata A, Tajada S, O'Dwyer S, Matsumoto C, Dixon RE, Hariharan N, Moreno CM, Santana LF. BIN1 Induces the Formation of T-Tubules and Adult-Like Ca Release Units in Developing Cardiomyocytes. Stem Cells (Dayton, Ohio). PMID 30353632 DOI: 10.1002/Stem.2927 |
0.393 |
|
| 2018 |
Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. Dynamic L-type Ca1.2 channel trafficking facilitates Ca1.2 clustering and cooperative gating. Biochimica Et Biophysica Acta. PMID 29959960 DOI: 10.1016/J.Bbamcr.2018.06.013 |
0.458 |
|
| 2018 |
Sato D, Dixon RE, Santana LF, Navedo MF. A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics. Plos Computational Biology. 14: e1005906. PMID 29338006 DOI: 10.1371/Journal.Pcbi.1005906 |
0.355 |
|
| 2017 |
Vivas O, Moreno CM, Santana LF, Hille B. Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage. Elife. 6. PMID 28665272 DOI: 10.7554/Elife.28029 |
0.454 |
|
| 2017 |
Tajada S, Moreno CM, O'Dwyer S, Woods S, Sato D, Navedo MF, Santana LF. Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes. The Journal of General Physiology. PMID 28507079 DOI: 10.1085/Jgp.201611709 |
0.447 |
|
| 2017 |
Ghosh D, Syed AU, Prada MP, Nystoriak MA, Santana LF, Nieves-Cintrón M, Navedo MF. Calcium Channels in Vascular Smooth Muscle. Advances in Pharmacology (San Diego, Calif.). 78: 49-87. PMID 28212803 DOI: 10.1016/Bs.Apha.2016.08.002 |
0.366 |
|
| 2016 |
Moreno CM, Dixon RE, Tajada S, Yuan C, Opitz-Araya X, Binder MD, Santana LF. Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels. Elife. 5. PMID 27187148 DOI: 10.7554/Elife.15744 |
0.613 |
|
| 2015 |
Nieves-Cintrón M, Hirenallur-S D, Nygren PJ, Hinke SA, Dell'Acqua ML, Langeberg LK, Navedo M, Santana LF, Scott JD. AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction. Cellular Signalling. PMID 26724383 DOI: 10.1016/J.Cellsig.2015.12.015 |
0.351 |
|
| 2015 |
Dixon RE, Moreno CM, Yuan C, Opitz-Araya X, Binder MD, Navedo MF, Santana LF. Graded Ca²⁺/calmodulin-dependent coupling of voltage-gated CaV1.2 channels. Elife. 4. PMID 25714924 DOI: 10.7554/Elife.05608 |
0.6 |
|
| 2014 |
Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, Nelson MT. AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Science Signaling. 7: ra66. PMID 25005230 DOI: 10.1126/Scisignal.2005052 |
0.436 |
|
| 2014 |
Mercado J, Baylie R, Navedo MF, Yuan C, Scott JD, Nelson MT, Brayden JE, Santana LF. Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. The Journal of General Physiology. 143: 559-75. PMID 24778429 DOI: 10.1083/Jcb.2053Oia89 |
0.456 |
|
| 2014 |
Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circulation Research. 114: 607-15. PMID 24323672 DOI: 10.1161/Circresaha.114.302168 |
0.37 |
|
| 2014 |
Drum BM, Dixon RE, Yuan C, Cheng EP, Santana LF. Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8). Journal of Molecular and Cellular Cardiology. 66: 63-71. PMID 24215710 DOI: 10.1016/J.Yjmcc.2013.10.021 |
0.397 |
|
| 2013 |
Tajada S, Cidad P, Colinas O, Santana LF, López-López JR, Pérez-García MT. Down-regulation of CaV1.2 channels during hypertension: How fewer CaV1.2 channels allow more Ca2+ into hypertensive arterial smooth muscle Journal of Physiology. 591: 6175-6191. PMID 24167226 DOI: 10.1113/jphysiol.2013.265751 |
0.454 |
|
| 2013 |
Navedo MF, Santana LF. CaV1.2 sparklets in heart and vascular smooth muscle. Journal of Molecular and Cellular Cardiology. 58: 67-76. PMID 23220157 DOI: 10.1016/J.Yjmcc.2012.11.018 |
0.422 |
|
| 2012 |
Dixon RE, Cheng EP, Mercado JL, Santana LF. L-type Ca2+ channel function during Timothy syndrome. Trends in Cardiovascular Medicine. 22: 72-6. PMID 22999068 DOI: 10.1016/J.Tcm.2012.06.015 |
0.432 |
|
| 2012 |
Dixon RE, Yuan C, Cheng EP, Navedo MF, Santana LF. Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 1749-54. PMID 22307641 DOI: 10.1073/Pnas.1116731109 |
0.408 |
|
| 2011 |
Takeda Y, Nystoriak MA, Nieves-Cintrón M, Santana LF, Navedo MF. Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 301: H2285-94. PMID 21984539 DOI: 10.1152/Ajpheart.00488.2011 |
0.302 |
|
| 2011 |
Cheng EP, Yuan C, Navedo MF, Dixon RE, Nieves-Cintrón M, Scott JD, Santana LF. Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circulation Research. 109: 255-61. PMID 21700933 DOI: 10.1161/Circresaha.111.248252 |
0.374 |
|
| 2010 |
Santana LF, Navedo MF. Natural inequalities: why some L-type Ca2+ channels work harder than others. The Journal of General Physiology. 136: 143-7. PMID 20660657 DOI: 10.1085/Jgp.200910391 |
0.372 |
|
| 2010 |
Patrucco E, Albergine MS, Santana LF, Beavo JA. Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes. Journal of Molecular and Cellular Cardiology. 49: 330-3. PMID 20353794 DOI: 10.1016/J.Yjmcc.2010.03.016 |
0.31 |
|
| 2010 |
Navedo MF, Cheng EP, Yuan C, Votaw S, Molkentin JD, Scott JD, Santana LF. Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circulation Research. 106: 748-56. PMID 20110531 DOI: 10.1161/Circresaha.109.213363 |
0.43 |
|
| 2009 |
Zhu WZ, Santana LF, Laflamme MA. Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes. Plos One. 4: e5407. PMID 19404384 DOI: 10.1371/Journal.Pone.0005407 |
0.325 |
|
| 2008 |
Santana LF. NFAT-dependent excitation-transcription coupling in heart. Circulation Research. 103: 681-3. PMID 18818410 DOI: 10.1161/Circresaha.108.185090 |
0.315 |
|
| 2008 |
Santana LF, Navedo MF, Amberg GC, Nieves-Cintrón M, Votaw VS, Ufret-Vincenty CA. Calcium sparklets in arterial smooth muscle. Clinical and Experimental Pharmacology & Physiology. 35: 1121-6. PMID 18215181 DOI: 10.1111/J.1440-1681.2007.04867.X |
0.323 |
|
| 2008 |
Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circulation Research. 102: e1-e11. PMID 18174462 DOI: 10.1161/Circresaha.107.167809 |
0.322 |
|
| 2007 |
Santana LF. SMAKing Ca2+ sparks in arterial myocytes. The Journal of Physiology. 584: 1. PMID 17717006 DOI: 10.1113/Jphysiol.2007.143529 |
0.341 |
|
| 2007 |
Navedo MF, Amberg GC, Westenbroek RE, Sinnegger-Brauns MJ, Catterall WA, Striessnig J, Santana LF. Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1359-70. PMID 17526649 DOI: 10.1152/Ajpheart.00450.2007 |
0.386 |
|
| 2007 |
Amberg GC, Navedo MF, Nieves-Cintrón M, Molkentin JD, Santana LF. Calcium sparklets regulate local and global calcium in murine arterial smooth muscle. The Journal of Physiology. 579: 187-201. PMID 17158168 DOI: 10.1113/Jphysiol.2006.124420 |
0.328 |
|
| 2007 |
Nieves-Cintrón M, Amberg GC, Nichols CB, Molkentin JD, Santana LF. Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension. The Journal of Biological Chemistry. 282: 3231-40. PMID 17148444 DOI: 10.1074/Jbc.M608822200 |
0.301 |
|
| 2006 |
Navedo MF, Amberg GC, Nieves M, Molkentin JD, Santana LF. Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. The Journal of General Physiology. 127: 611-22. PMID 16702354 DOI: 10.1085/Jgp.200609519 |
0.377 |
|
| 2006 |
Rossow CF, Dilly KW, Santana LF. Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart. Circulation Research. 98: 1306-13. PMID 16614306 DOI: 10.1161/01.Res.0000222028.92993.10 |
0.349 |
|
| 2006 |
Amberg GC, Santana LF. Kv2 channels oppose myogenic constriction of rat cerebral arteries. American Journal of Physiology. Cell Physiology. 291: C348-56. PMID 16571867 DOI: 10.1152/Ajpcell.00086.2006 |
0.358 |
|
| 2006 |
Amberg GC, Navedo MF, Santana LF. On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle. The Journal of General Physiology. 127: 221-3. PMID 16505144 DOI: 10.1085/Jgp.200609510 |
0.316 |
|
| 2005 |
Navedo MF, Amberg GC, Votaw VS, Santana LF. Constitutively active L-type Ca2+ channels. Proceedings of the National Academy of Sciences of the United States of America. 102: 11112-7. PMID 16040810 DOI: 10.1073/Pnas.0500360102 |
0.381 |
|
| 2004 |
Amberg GC, Rossow CF, Navedo MF, Santana LF. NFATc3 regulates Kv2.1 expression in arterial smooth muscle. The Journal of Biological Chemistry. 279: 47326-34. PMID 15322114 DOI: 10.1074/Jbc.M408789200 |
0.31 |
|
| 2003 |
Amberg GC, Santana LF. Downregulation of the BK channel beta1 subunit in genetic hypertension. Circulation Research. 93: 965-71. PMID 14551242 DOI: 10.1161/01.Res.0000100068.43006.36 |
0.437 |
|
| 2003 |
Amberg GC, Bonev AD, Rossow CF, Nelson MT, Santana LF. Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. The Journal of Clinical Investigation. 112: 717-24. PMID 12952920 DOI: 10.1172/Jci18684 |
0.409 |
|
| 2002 |
Guatimosim S, Dilly K, Santana LF, Saleet Jafri M, Sobie EA, Lederer WJ. Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient. Journal of Molecular and Cellular Cardiology. 34: 941-50. PMID 12234764 DOI: 10.1006/Jmcc.2002.2032 |
0.309 |
|
| 2001 |
Wellman GC, Santana LF, Bonev AD, Nelson MT. Role of phospholamban in the modulation of arterial Ca(2+) sparks and Ca(2+)-activated K(+) channels by cAMP. American Journal of Physiology. Cell Physiology. 281: C1029-37. PMID 11502581 DOI: 10.1152/Ajpcell.2001.281.3.C1029 |
0.313 |
|
| 1998 |
Santana LF, Gómez AM, Lederer WJ. Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance. Science (New York, N.Y.). 279: 1027-33. PMID 9461434 DOI: 10.1126/Science.279.5353.1027 |
0.383 |
|
| 1996 |
Santana LF, Cheng H, Gómez AM, Cannell MB, Lederer WJ. Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling. Circulation Research. 78: 166-71. PMID 8603501 DOI: 10.1161/01.Res.78.1.166 |
0.353 |
|
| 1995 |
Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks. Science (New York, N.Y.). 270: 633-7. PMID 7570021 DOI: 10.1126/Science.270.5236.633 |
0.376 |
|
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