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Richard Isaacs, DPhil - Publications

Affiliations: 
1993-1997 University of Oxford, Oxford, United Kingdom 
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0/62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2021 Cheshire J, Lissauer D, Parry-Smith W, Tobias A, Smith GB, Isaacs R, Hundley V. Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units. Resuscitation Plus. 5: 100060. PMID 34223332 DOI: 10.1016/j.resplu.2020.100060  0.01
2021 Lo E, Anderson M, Carroll R, Forgeson G, Isaacs R, Jordan J, Satterthwaite L, Wewala N, Fernando J. A prospective audit on the use of prophylactic antiemetics and rates of CINV in patients receiving carboplatin AUC≥4 or combination anthracycline-cyclophosphamide. The New Zealand Medical Journal. 134: 33-45. PMID 33927422  0.01
2021 Malhotra L, Pontarelli EM, Grinberg GG, Isaacs RS, Morris JP, Yenumula PR. Correction to: Cost analysis of laparoscopic appendectomy in a large integrated healthcare system. Surgical Endoscopy. PMID 33616733 DOI: 10.1007/s00464-021-08356-7  0.01
2021 Malhotra L, Pontarelli EM, Grinberg GG, Isaacs RS, Morris JP, Yenumula PR. Cost analysis of laparoscopic appendectomy in a large integrated healthcare system. Surgical Endoscopy. PMID 33502616 DOI: 10.1007/s00464-020-08266-0  0.01
2020 Lebbé C, Dutriaux C, Lesimple T, Kruit W, Kerger J, Thomas L, Guillot B, Braud F, Garbe C, Grob JJ, Loquai C, Ferraresi V, Robert C, Vasey P, Conry R, ... Isaacs R, et al. Pimasertib Versus Dacarbazine in Patients With Unresectable -Mutated Cutaneous Melanoma: Phase II, Randomized, Controlled Trial with Crossover. Cancers. 12. PMID 32610581 DOI: 10.3390/cancers12071727  0.01
2019 Ang E, Wewala N, Carroll R, Forgeson G, Anderson M, Fernando J, Jordan J, Isaacs R. Neoadjuvant Chemotherapy in Non-Metastatic Breast Cancer- A Study on Practice Trends in a Regional Cancer Treatment Service. Internal Medicine Journal. PMID 30989751 DOI: 10.1111/imj.14326  0.01
2018 Pontarelli EM, Grinberg GG, Isaacs RS, Morris JP, Ajayi O, Yenumula PR. Regional cost analysis for laparoscopic cholecystectomy. Surgical Endoscopy. PMID 30488194 DOI: 10.1007/s00464-018-6526-0  0.01
2018 Ellery J, Dickson L, Cheung T, Ciuclan L, Bunyard P, Mack S, Buffham WJ, Farnaby W, Mitchell P, Brown D, Isaacs R, Barnes M. Identification of compounds acting as negative allosteric modulators of the LPA receptor. European Journal of Pharmacology. PMID 29807028 DOI: 10.1016/j.ejphar.2018.05.040  0.01
2017 Loja MN, Abbot C, Isaacs R, Brawley J, Humphries M. Staged Definitive Repair after Carotid Blowout: A Case Report. Annals of Vascular Surgery. 45: 263.e5-263.e9. PMID 28666819 DOI: 10.1016/j.avsg.2017.06.031  0.01
2016 Isaacs RC, Harper MM, Miller EC. Analytical challenges in the confirmative identification of dipyrone as an adulterant in illicit drug samples. Forensic Science International. PMID 27823839 DOI: 10.1016/j.forsciint.2016.08.023  0.01
2016 van Hazel GA, Heinemann V, Sharma NK, Findlay MP, Ricke J, Peeters M, Perez D, Robinson BA, Strickland AH, Ferguson T, Rodrigez J, Kröning H, Wolf I, Ganju V, Walpole E, ... ... Isaacs R, et al. SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26903575 DOI: 10.1200/JCO.2015.66.1181  0.01
2015 Fjellström O, Larsson N, Yasuda SI, Tsuchida T, Oguma T, Marley A, Wennberg-Huldt C, Hovdal D, Fukuda H, Yoneyama Y, Sasaki K, Johansson A, Lundqvist S, Brengdahl J, Isaacs RJ, et al. Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents. Plos One. 10: e0145849. PMID 26720709 DOI: 10.1371/journal.pone.0145849  0.01
2015 Xu H, Hill JJ, Michelsen K, Yamane H, Kurzeja R, Tam T, Isaacs RJ, Shen F, Tagari P. Characterization of the direct interaction between KcsA-Kv1.3 and its inhibitors. Biochimica Et Biophysica Acta. PMID 26074010 DOI: 10.1016/j.bbamem.2015.06.011  0.01
2015 May AK, Brady JS, Romano-Keeler J, Drake WP, Norris PR, Jenkins JM, Isaacs RJ, Boczko EM. A pilot study of the noninvasive assessment of the lung microbiota as a potential tool for the early diagnosis of ventilator-associated pneumonia. Chest. 147: 1494-502. PMID 25474571 DOI: 10.1378/Chest.14-1687  0.01
2014 Jackson CG, Sharples K, Thompson PI, O'Donnell A, Robinson BA, Perez DJ, Adams J, Isaacs R, Deva S, Hinder VA, Findlay MP. Dose-intense capecitabine, oxaliplatin and bevacizumab as first line treatment for metastatic, unresectable colorectal cancer: a multi-centre phase II study. Bmc Cancer. 14: 737. PMID 25274181 DOI: 10.1186/1471-2407-14-737  0.01
2014 Vaughan N, Dubey VN, Wee MY, Isaacs R. Parametric model of human body shape and ligaments for patient-specific epidural simulation. Artificial Intelligence in Medicine. 62: 129-40. PMID 25217137 DOI: 10.1016/j.artmed.2014.08.005  0.01
2014 Isaacs RCA. A structure-reactivity relationship driven approach to the identification of a color test protocol for the presumptive indication of synthetic cannabimimetic drugs of abuse. Forensic Science International. 242: 135-141. PMID 25062530 DOI: 10.1016/j.forsciint.2014.06.027  0.01
2014 Bick DE, Sandall J, Furuta M, Wee MY, Isaacs R, Smith GB, Beake S. A national cross sectional survey of heads of midwifery services of uptake, benefits and barriers to use of obstetric early warning systems (EWS) by midwives. Midwifery. 30: 1140-6. PMID 24820002 DOI: 10.1016/j.midw.2014.03.016  0.01
2014 D'mello SA, Flanagan JU, Green TN, Leung EY, Askarian-Amiri ME, Joseph WR, McCrystal MR, Isaacs RJ, Shaw JH, Furneaux CE, During MJ, Finlay GJ, Baguley BC, Kalev-Zylinska ML. Evidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival. Frontiers in Oncology. 3: 333. PMID 24455489 DOI: 10.3389/fonc.2013.00333  0.01
2013 Guppy KH, Chakrabarti I, Isaacs RS, Jun JH. En bloc resection of a multilevel high-cervical chordoma involving C-2: new operative modalities: technical note. Journal of Neurosurgery. Spine. 19: 232-42. PMID 23768022 DOI: 10.3171/2013.5.SPINE121039  0.01
2013 Vaughan N, Dubey VN, Wee MY, Isaacs R. Towards a realistic in vitro experience of epidural Tuohy needle insertion. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine. 227: 767-77. PMID 23636758 DOI: 10.1177/0954411913483428  0.01
2013 Vaughan N, Dubey VN, Wee MY, Isaacs R. A review of epidural simulators: where are we today? Medical Engineering & Physics. 35: 1235-50. PMID 23545132 DOI: 10.1016/j.medengphy.2013.03.003  0.01
2012 Isaacs RJ, Debelak K, Norris PR, Jenkins JM, Rooks JC, Young TR, May AK, Boczko EM. Non-invasive detection of pulmonary pathogens in ventilator-circuit filters by PCR. American Journal of Translational Research. 4: 72-82. PMID 22347523  0.01
2012 Magan N, Isaacs RJ, Stowell KM. Treatment with the PARP-inhibitor PJ34 causes enhanced doxorubicin-mediated cell death in HeLa cells. Anti-Cancer Drugs. 23: 627-37. PMID 22293659 DOI: 10.1097/CAD.0b013e328350900f  0.01
2012 Sun J, Gao Y, Isaacs RJ, Boelte KC, Lin PC, Boczko EM, Li D. Simultaneous on-chip DC dielectrophoretic cell separation and quantitative separation performance characterization. Analytical Chemistry. 84: 2017-24. PMID 22229858 DOI: 10.1021/Ac203212G  0.01
2011 Isaacs RC, Newton CL, Cutrona KJ, Mercer SP, Payne LS, Stauffer KJ, Williams PD, Cook JJ, Krueger JA, Lewis SD, Lucas BJ, Lyle EA, Lynch JJ, McMasters DR, Naylor-Olsen AM, et al. Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1536-40. PMID 21295467 DOI: 10.1016/j.bmcl.2010.12.105  0.01
2011 Isaacs RC, Newton CL, Cutrona KJ, Mercer SP, Dorsey BD, McDonough CM, Cook JJ, Krueger JA, Lewis SD, Lucas BJ, Lyle EA, Lynch JJ, Miller-Stein C, Michener MT, Wallace AA, et al. P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position. Bioorganic & Medicinal Chemistry Letters. 21: 1532-5. PMID 21295466 DOI: 10.1016/j.bmcl.2010.12.108  0.01
2010 Hahn Y, Isaacs R, Belafsky PC. Laryngeal paraganglioma. Ear, Nose, & Throat Journal. 89: 482-3. PMID 20981658  0.01
2008 Green N, Ott RD, Isaacs RJ, Fang H. Cell-based Assays to Identify Inhibitors of Viral Disease. Expert Opinion On Drug Discovery. 3: 671-676. PMID 19750206 DOI: 10.1517/17460441.3.6.671  0.01
2008 Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, McMasters DR, Krueger JA, Lewis SD, Lucas BJ, Kuo LC, Yan Y, Lynch JJ, Lyle EA. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorganic & Medicinal Chemistry Letters. 18: 2062-6. PMID 18291642 DOI: 10.1016/j.bmcl.2008.01.098  0.01
2007 Isaacs RJ, Frampton CM, Kuper-Hommel MJ. PHARMAC's funding of 9 weeks Herceptin: many assumptions in a high-risk decision. The New Zealand Medical Journal. 120: U2676. PMID 17721579  0.01
2007 Williams AO, Isaacs RJ, Stowell KM. Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regions. Bmc Molecular Biology. 8: 36. PMID 17511886 DOI: 10.1186/1471-2199-8-36  0.01
2007 Williams AO, Isaacs RJ, Stowell KM. Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regions. Bmc Molecular Biology. 8: 36. PMID 17511886 DOI: 10.1186/1471-2199-8-36  0.01
2007 Koehn H, Magan N, Isaacs RJ, Stowell KM. Differential regulation of DNA repair protein Rad51 in human tumour cell lines exposed to doxorubicin. Anti-Cancer Drugs. 18: 419-25. PMID 17351394 DOI: 10.1097/CAD.0b013e328012a9a0  0.01
2007 Koehn H, Magan N, Isaacs RJ, Stowell KM. Differential regulation of DNA repair protein Rad51 in human tumour cell lines exposed to doxorubicin. Anti-Cancer Drugs. 18: 419-25. PMID 17351394 DOI: 10.1097/CAD.0b013e328012a9a0  0.01
2006 Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, Krueger JA, Lewis SD, Lucas BJ. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 1: Weakly basic azoles. Bioorganic & Medicinal Chemistry Letters. 16: 338-42. PMID 16257203 DOI: 10.1016/j.bmcl.2005.09.083  0.01
2006 Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, Krueger JA, Lewis SD, Lucas BJ. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 1: Weakly basic azoles. Bioorganic & Medicinal Chemistry Letters. 16: 338-42. PMID 16257203 DOI: 10.1016/j.bmcl.2005.09.083  0.01
2004 Liu JJ, Kestell P, Findlay M, Riley G, Ackland S, Simpson A, Isaacs R, McKeage MJ. Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients. Clinical and Experimental Pharmacology & Physiology. 31: 677-82. PMID 15554907 DOI: 10.1111/j.1440-1681.2004.03065.x  0.01
2004 Liu JJ, Kestell P, Findlay M, Riley G, Ackland S, Simpson A, Isaacs R, McKeage MJ. Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients. Clinical and Experimental Pharmacology & Physiology. 31: 677-82. PMID 15554907 DOI: 10.1111/j.1440-1681.2004.03065.x  0.01
2004 Davidson JA, Isaacs RA. A novel case of numb bum. European Journal of Emergency Medicine : Official Journal of the European Society For Emergency Medicine. 11: 285-6. PMID 15359203  0.01
2004 Marshall ES, Baguley BC, Matthews JH, Jose CC, Furneaux CE, Shaw JH, Kirker JA, Morton RP, White JB, Rice ML, Isaacs RJ, Coutts R, Whittaker JR. Estimation of radiation-induced interphase cell death in cultures of human tumor material and in cell lines. Oncology Research. 14: 297-304. PMID 15206492  0.01
2004 Marshall ES, Baguley BC, Matthews JH, Jose CC, Furneaux CE, Shaw JH, Kirker JA, Morton RP, White JB, Rice ML, Isaacs RJ, Coutts R, Whittaker JR. Estimation of radiation-induced interphase cell death in cultures of human tumor material and in cell lines. Oncology Research. 14: 297-304. PMID 15206492  0.01
2004 Isaacs RJ, Spielmann HP. A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility. Dna Repair. 3: 455-64. PMID 15162792 DOI: 10.1016/J.Dnarep.2004.01.004  0.01
2004 Isaacs RJ, Spielmann HP. A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility. Dna Repair. 3: 455-64. PMID 15162792 DOI: 10.1016/J.Dnarep.2004.01.004  0.01
2004 Neale JC, Goulden JW, Allan SG, Dixon PD, Isaacs RJ. Esophageal stents in malignant dysphagia: a two-edged sword? Journal of Palliative Care. 20: 28-31. PMID 15132073  0.01
2004 Neale JC, Goulden JW, Allan SG, Dixon PD, Isaacs RJ. Esophageal stents in malignant dysphagia: a two-edged sword? Journal of Palliative Care. 20: 28-31. PMID 15132073  0.01
2004 Allen KA, Williams AO, Isaacs RJ, Stowell KM. Down-regulation of human topoisomerase IIalpha correlates with altered expression of transcriptional regulators NF-YA and Sp1. Anti-Cancer Drugs. 15: 357-62. PMID 15057140 DOI: 10.1097/00001813-200404000-00008  0.01
2004 Allen KA, Williams AO, Isaacs RJ, Stowell KM. Down-regulation of human topoisomerase IIalpha correlates with altered expression of transcriptional regulators NF-YA and Sp1. Anti-Cancer Drugs. 15: 357-62. PMID 15057140 DOI: 10.1097/00001813-200404000-00008  0.01
2004 Isaacs RJ, Spielmann HP. Insight into G[bond]T mismatch recognition using molecular dynamics with time-averaged restraints derived from NMR spectroscopy. Journal of the American Chemical Society. 126: 583-90. PMID 14719957 DOI: 10.1021/Ja037333R  0.01
2004 Isaacs RJ, Spielmann HP. Insight into G[bond]T mismatch recognition using molecular dynamics with time-averaged restraints derived from NMR spectroscopy. Journal of the American Chemical Society. 126: 583-90. PMID 14719957 DOI: 10.1021/Ja037333R  0.01
2003 Magan N, Szremska AP, Isaacs RJ, Stowell KM. Modulation of DNA topoisomerase II alpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors. The Biochemical Journal. 374: 723-9. PMID 12769819 DOI: 10.1042/BJ20030032  0.01
2003 Magan N, Szremska AP, Isaacs RJ, Stowell KM. Modulation of DNA topoisomerase II alpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors. The Biochemical Journal. 374: 723-9. PMID 12769819 DOI: 10.1042/BJ20030032  0.01
2003 Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, et al. Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides. Bioorganic & Medicinal Chemistry Letters. 13: 1353-7. PMID 12657281 DOI: 10.1016/S0960-894X(03)00099-4  0.01
2003 Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, et al. Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides. Bioorganic & Medicinal Chemistry Letters. 13: 1353-7. PMID 12657281 DOI: 10.1016/S0960-894X(03)00099-4  0.01
2003 Chrystal K, Allan S, Forgeson G, Isaacs R. The use of complementary/alternative medicine by cancer patients in a New Zealand regional cancer treatment centre. The New Zealand Medical Journal. 116: U296. PMID 12601420  0.01
2003 Chrystal K, Allan S, Forgeson G, Isaacs R. The use of complementary/alternative medicine by cancer patients in a New Zealand regional cancer treatment centre. The New Zealand Medical Journal. 116: U296. PMID 12601420  0.01
2002 Isaacs RS, Sykes JM. Anatomy and physiology of the upper airway. Anesthesiology Clinics of North America. 20: 733-45, v. PMID 12512260 DOI: 10.1016/S0889-8537(02)00017-2  0.01
2002 Isaacs RS, Sykes JM. Anatomy and physiology of the upper airway. Anesthesiology Clinics of North America. 20: 733-45, v. PMID 12512260 DOI: 10.1016/S0889-8537(02)00017-2  0.01
2002 Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Journal of the American Chemical Society. 124: 8206-19. PMID 12105898 DOI: 10.1021/Ja0124717  0.01
2002 Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Journal of the American Chemical Society. 124: 8206-19. PMID 12105898 DOI: 10.1021/Ja0124717  0.01
2002 Isaacs RJ, Rayens WS, Spielmann HP. Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics. Journal of Molecular Biology. 319: 191-207. PMID 12051946 DOI: 10.1016/S0022-2836(02)00265-6  0.01
2002 Isaacs RJ, Rayens WS, Spielmann HP. Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics. Journal of Molecular Biology. 319: 191-207. PMID 12051946 DOI: 10.1016/S0022-2836(02)00265-6  0.01
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