Russell Leek - Publications

1995-1999 University of Oxford, Oxford, United Kingdom 

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sheldon H, Bridges E, Silva I, Masiero M, Favara DM, Wang D, Leek R, Snell C, Roxanis I, Kreuzer M, Gileadi U, Buffa FM, Banham A, Harris AL. ADGRL4/ELTD1 expression in breast cancer cells induces vascular normalisation and immune suppression. Molecular Cancer Research : McR. PMID 34348993 DOI: 10.1158/1541-7786.MCR-21-0171  0.816
2017 Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. PMID 28445154 DOI: 10.18632/oncotarget.16969  0.793
2017 Suh YE, Lawler K, Henley-Smith R, Pike L, Leek R, Barrington S, Odell EW, Ng T, Pezzella F, Guerrero-Urbano T, Tavassoli M. Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma. British Journal of Cancer. PMID 28324887 DOI: 10.1038/bjc.2017.66  0.533
2016 Leek R, Grimes DR, Harris AL, McIntyre A. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia. Advances in Experimental Medicine and Biology. 899: 167-96. PMID 27325267 DOI: 10.1007/978-3-319-26666-4_10  0.355
2016 Adighibe O, Leek RD, Fernandez-Mercado M, Hu J, Snell C, Gatter KC, Harris AL, Pezzella F. Why some tumours trigger neovascularisation and others don't: the story thus far. Chinese Journal of Cancer. 35: 18. PMID 26873439 DOI: 10.1186/s40880-016-0082-6  0.776
2016 Chen L, Zeng X, Kleibeuker E, Buffa F, Barberis A, Leek RD, Roxanis I, Zhang W, Worth A, Beech JS, Harris AL, Cai S. Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth. Oncotarget. PMID 26814432 DOI: 10.18632/oncotarget.6981  0.836
2016 Tan K, Haider S, Zois C, Turley H, Leek R, Harris A, Buffa F, Acuto O, Pezzella F. NUB1 protein regulates cullins and E3 ligases in estrogen receptor negative breast cancers European Journal of Cancer. 61: S190. DOI: 10.1016/S0959-8049(16)61672-6  0.691
2015 Chiorean EG, LoRusso P, Strother RM, Diamond JR, Younger A, Messersmith WA, Adriaens L, Liu L, Kao RJ, DiCioccio AT, Kostic A, Leek R, Harris A, Jimeno A. A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2695-703. PMID 25724527 DOI: 10.1158/1078-0432.Ccr-14-2797  0.355
2014 Kato T, Pezzella F, Steers G, Campo L, Leek RD, Turley H, Kameoka S, Nishikawa T, Harris AL, Gatter KC, Fox S. Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer. International Journal of Clinical and Experimental Pathology. 7: 7967-78. PMID 25550840  0.771
2014 Adighibe O, Turley H, Leek R, Harris A, Coutts AS, La Thangue N, Gatter K, Pezzella F. JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues. Virchows Archiv : An International Journal of Pathology. 465: 715-22. PMID 25280461 DOI: 10.1007/s00428-014-1660-0  0.761
2014 Feldinger K, Generali D, Kramer-Marek G, Gijsen M, Ng TB, Wong JH, Strina C, Cappelletti M, Andreis D, Li JL, Bridges E, Turley H, Leek R, Roxanis I, Capala J, et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget. 5: 6633-46. PMID 24952873  0.783
2014 Airley RE, McHugh P, Evans AR, Harris B, Winchester L, Buffa FM, Al-Tameemi W, Leek R, Harris AL. Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression. British Journal of Cancer. 110: 715-23. PMID 24366300 DOI: 10.1038/bjc.2013.765  0.769
2014 Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Li JL, Harris AL. Functional comparison of Notch ligands in tumour angiogenesis Asian Pacific Journal of Tropical Disease. 4: 229. DOI: 10.1016/S2222-1808(14)60523-5  0.772
2013 Nikitenko LL, Leek R, Henderson S, Pillay N, Turley H, Generali D, Gunningham S, Morrin HR, Pellagatti A, Rees MC, Harris AL, Fox SB. The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5740-8. PMID 23969937 DOI: 10.1158/1078-0432.CCR-13-1712  0.786
2013 Kumar K, Wigfield S, Gee HE, Devlin CM, Singleton D, Li JL, Buffa F, Huffman M, Sinn AL, Silver J, Turley H, Leek R, Harris AL, Ivan M. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine (Berlin, Germany). 91: 749-58. PMID 23361368 DOI: 10.1007/s00109-013-0996-2  0.778
2013 Al-Ebraheem A, Geraki K, Leek R, Harris AL, Farquharson MJ. The use of bio-metal concentrations correlated with clinical prognostic factors to assess human breast tissues X-Ray Spectrometry. 42: 330-336. DOI: 10.1002/xrs.2463  0.367
2012 Biswas S, Charlesworth PJ, Turner GD, Leek R, Thamboo PT, Campo L, Turley H, Dildey P, Protheroe A, Cranston D, Gatter KC, Pezzella F, Harris AL. CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC. Carcinogenesis. 33: 1717-25. PMID 22777959 DOI: 10.1093/carcin/bgs222  0.801
2012 McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877  0.791
2012 Airley R, Evans A, Harris B, Winchester L, Leek R, Harris A. 329 Carbohydrate Response Element Binding Protein (ChREBP) -a New Metabolic Biomarker in Breast Cancer? European Journal of Cancer. 48: S80. DOI: 10.1016/S0959-8049(12)71019-5  0.692
2011 Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704  0.794
2010 Chen L, Zeng X, Wang J, Briggs SS, O'Neill E, Li J, Leek R, Kerr DJ, Harris AL, Cai S. Roles of tetrahydrobiopterin in promoting tumor angiogenesis. The American Journal of Pathology. 177: 2671-80. PMID 20847284 DOI: 10.2353/ajpath.2010.100025  0.717
2010 Yang J, Jubb AM, Pike L, Buffa FM, Turley H, Baban D, Leek R, Gatter KC, Ragoussis J, Harris AL. The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Research. 70: 6456-66. PMID 20682797 DOI: 10.1158/0008-5472.CAN-10-0413  0.803
2010 Biswas S, Troy H, Leek R, Chung YL, Li JL, Raval RR, Turley H, Gatter K, Pezzella F, Griffiths JR, Stubbs M, Harris AL. Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. Journal of Oncology. 2010: 757908. PMID 20652061 DOI: 10.1155/2010/757908  0.794
2010 Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116: 2385-94. PMID 20558614 DOI: 10.1182/blood-2009-08-239228  0.783
2010 Jubb AM, Soilleux EJ, Turley H, Steers G, Parker A, Low I, Blades J, Li JL, Allen P, Leek R, Noguera-Troise I, Gatter KC, Thurston G, Harris AL. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. The American Journal of Pathology. 176: 2019-28. PMID 20167860 DOI: 10.2353/ajpath.2010.090908  0.821
2010 Charlesworth PJ, Kilbey N, Taylor M, Leek R, Cranston D, Turner G, Crew J, Harris A, Protheroe A. Automated uro-oncology data collection: the Cancer Research Uro-Oncology Database. Bju International. 105: 1663-6. PMID 19930178 DOI: 10.1111/j.1464-410X.2009.09058.x  0.762
2010 Oon C, Li J, Sainson R, Sheldon H, Turley H, Leek R, Harris A. 360 Role of DLL4 and JAG1 in tumour angiogenesis European Journal of Cancer Supplements. 8: 92. DOI: 10.1016/S1359-6349(10)71161-7  0.789
2009 Koukourakis MI, Giatromanolaki A, Winter S, Leek R, Sivridis E, Harris AL. Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy. Oncology. 77: 285-92. PMID 19923867 DOI: 10.1159/000259260  0.717
2009 Jubb AM, Turley H, Moeller HC, Steers G, Han C, Li JL, Leek R, Tan EY, Singh B, Mortensen NJ, Noguera-Troise I, Pezzella F, Gatter KC, Thurston G, Fox SB, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. British Journal of Cancer. 101: 1749-57. PMID 19844231 DOI: 10.1038/sj.bjc.6605368  0.83
2009 Farquharson MJ, Al-Ebraheem A, Geraki K, Leek R, Jubb A, Harris AL. Zinc presence in invasive ductal carcinoma of the breast and its correlation with oestrogen receptor status. Physics in Medicine and Biology. 54: 4213-23. PMID 19521003 DOI: 10.1088/0031-9155/54/13/016  0.671
2008 Farquharson MJ, Al-Ebraheem A, Falkenberg G, Leek R, Harris AL, Bradley DA. The distribution of trace elements Ca, Fe, Cu and Zn and the determination of copper oxidation state in breast tumour tissue using muSRXRF and muXANES. Physics in Medicine and Biology. 53: 3023-37. PMID 18490810 DOI: 10.1088/0031-9155/53/11/018  0.325
2008 Bates GJ, Fox SB, Han C, Launchbury R, Leek RD, Harris AL, Banham AH. Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas. Breast Cancer Research and Treatment. 111: 453-9. PMID 18026833 DOI: 10.1007/s10549-007-9812-4  0.613
2007 Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL. Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Research. 67: 11244-53. PMID 18056450 DOI: 10.1158/0008-5472.CAN-07-0969  0.798
2007 Kato T, Steers G, Campo L, Roberts H, Leek RD, Turley H, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Harris AL, Gatter KC, Pezzella F. Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. British Journal of Cancer. 97: 1277-86. PMID 17923874 DOI: 10.1038/sj.bjc.6604015  0.715
2007 Generali D, Leek R, Fox SB, Moore JW, Taylor C, Chambers P, Harris AL. EGFR mutations in exons 18-21 in sporadic breast cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 18: 203-5. PMID 17220285 DOI: 10.1093/annonc/mdl322  0.638
2007 Sainson RCA, Li J, Harrington L, Shi W, Heikamp E, Leek R, Harris AL. In vivo assessment of Delta like‐4 function in tumour development The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a16  0.764
2006 Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, Banham AH. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 5373-80. PMID 17135638 DOI: 10.1200/JCO.2006.05.9584  0.611
2006 Farquharson MJ, Geraki K, Falkenberg G, Leek R, Harris A. The localisation and micro-mapping of copper and other trace elements in breast tumours using a synchrotron micro-XRF system. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 65: 183-8. PMID 17052909 DOI: 10.1016/J.APRADISO.2006.08.013  0.365
2006 Nikitenko LL, Cross T, Campo L, Turley H, Leek R, Manek S, Bicknell R, Rees MC. Expression of terminally glycosylated calcitonin receptor-like receptor in uterine leiomyoma: endothelial phenotype and association with microvascular density. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5648-58. PMID 17020966 DOI: 10.1158/1078-0432.CCR-06-0852  0.592
2006 Winter SC, Shah KA, Han C, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. The relation between hypoxia-inducible factor (HIF)=1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer Cancer. 107: 757-766. PMID 16826581 DOI: 10.1002/cncr.21983  0.739
2006 Kong A, Leboucher P, Leek R, Calleja V, Winter S, Harris A, Parker PJ, Larijani B. Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer. Cancer Research. 66: 2834-43. PMID 16510606 DOI: 10.1158/0008-5472.CAN-05-2994  0.753
2006 Robertson N, Leek R. Isolation of DNA from tumor samples. Methods in Molecular Medicine. 120: 61-3. PMID 16491594 DOI: 10.1385/1-59259-969-9:61  0.733
2006 Robertson N, Leek R. Isolation of RNA from tumor samples: single-step guanidinium acid-phenol method. Methods in Molecular Medicine. 120: 55-9. PMID 16491593 DOI: 10.1385/1-59259-969-9:55  0.715
2006 Robertson N, Leek R. Preparation of tumor homogenates for subsequent preparation of cytosols, membrane fractions, RNA, and DNA. Methods in Molecular Medicine. 120: 51-3. PMID 16491592 DOI: 10.1385/1-59259-969-9:51  0.747
2005 Winter SC, Shah KA, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma Clinical Cancer Research. 11: 7614-7620. PMID 16278379 DOI: 10.1158/1078-0432.CCR-05-1097  0.755
2005 Kato T, Prevo R, Steers G, Roberts H, Leek RD, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Jackson DG, Harris AL, Gatter KC, Pezzella F. A quantitative analysis of lymphatic vessels in human breast cancer, based on LYVE-1 immunoreactivity. British Journal of Cancer. 93: 1168-74. PMID 16251871 DOI: 10.1038/sj.bjc.6602844  0.659
2005 Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Niederwieser D, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. Journal of Cancer Research and Clinical Oncology. 131: 741-50. PMID 16136355 DOI: 10.1007/s00432-005-0024-1  0.789
2005 Couvelard A, O'Toole D, Leek R, Turley H, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas. Histopathology. 46: 668-76. PMID 15910598 DOI: 10.1111/j.1365-2559.2005.02160.x  0.735
2005 Leek RD, Stratford I, Harris AL. The role of hypoxia-inducible factor-1 in three-dimensional tumor growth, apoptosis, and regulation by the insulin-signaling pathway. Cancer Research. 65: 4147-52. PMID 15899805 DOI: 10.1158/0008-5472.CAN-04-2184  0.421
2005 Raida M, Clement JH, Ameri K, Han C, Leek RD, Harris AL. Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death. International Journal of Oncology. 26: 1465-70. PMID 15870857  0.813
2005 Pillai G, Cook N, Turley H, Leek RD, Blasquez C, Pezzella F, Harris AL, Gatter KC. The expression and cellular localization of phosphorylated VEGFR2 in lymphoma and non-neoplastic lymphadenopathy: an immunohistochemical study. Histopathology. 46: 209-16. PMID 15693894 DOI: 10.1111/j.1365-2559.2005.02081.x  0.73
2005 Couvelard A, O'Toole D, Turley H, Leek R, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. British Journal of Cancer. 92: 94-101. PMID 15558070 DOI: 10.1038/sj.bjc.6602245  0.762
2004 Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9531. PMID 28016826 DOI: 10.1200/jco.2004.22.14_suppl.9531  0.731
2004 Chung YL, Troy H, Judson IR, Leek R, Leach MO, Stubbs M, Harris AL, Griffiths JR. Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy Clinical Cancer Research. 10: 3863-3870. PMID 15173095 DOI: 10.1158/1078-0432.CCR-03-0237  0.41
2004 Fox SB, Brown P, Han C, Ashe S, Leek RD, Harris AL, Banham AH. Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3521-7. PMID 15161711 DOI: 10.1158/1078-0432.CCR-03-0461  0.621
2004 Knowles H, Leek R, Harris AL. Macrophage infiltration and angiogenesis in human malignancy. Novartis Foundation Symposium. 256: 189-200; discussion . PMID 15027491  0.713
2004 Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis Journal of Clinical Oncology. 22: 9531-9531. DOI: 10.1200/jco.2004.22.90140.9531  0.695
2003 Winters ZE, Leek RD, Bradburn MJ, Norbury CJ, Harris AL. Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis. Breast Cancer Research : Bcr. 5: R242-9. PMID 14580260 DOI: 10.1186/Bcr654  0.802
2003 Williams CS, Leek RD, Robson AM, Banerji S, Prevo R, Harris AL, Jackson DG. Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer. The Journal of Pathology. 200: 195-206. PMID 12754740 DOI: 10.1002/path.1343  0.758
2003 Watson PH, Chia SK, Wykoff CC, Han C, Leek RD, Sly WS, Gatter KC, Ratcliffe P, Harris AL. Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. British Journal of Cancer. 88: 1065-70. PMID 12671706 DOI: 10.1038/Sj.Bjc.6600796  0.447
2003 Leek RD, Harris AL. Tumor-associated macrophages in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 7: 177-89. PMID 12463738 DOI: 10.1023/A:1020304003704  0.505
2002 Wilson KS, Roberts H, Leek R, Harris AL, Geradts J. Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. The American Journal of Pathology. 161: 1171-85. PMID 12368191 DOI: 10.1016/S0002-9440(10)64394-5  0.479
2002 Turner KJ, Moore JW, Jones A, Taylor CF, Cuthbert-Heavens D, Han C, Leek RD, Gatter KC, Maxwell PH, Ratcliffe PJ, Cranston D, Harris AL. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Research. 62: 2957-61. PMID 12019178  0.744
2002 Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, Millard P, Fuggle S, Harris AL. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Research. 62: 2493-7. PMID 11980639  0.666
2002 Stewart M, Talks K, Leek R, Turley H, Pezzella F, Harris A, Gatter K. Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma. Histopathology. 40: 253-60. PMID 11895491 DOI: 10.1046/j.1365-2559.2002.01357.x  0.803
2002 Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Research. 62: 1326-9. PMID 11888900  0.83
2002 Beasley NJ, Prevo R, Banerji S, Leek RD, Moore J, van Trappen P, Cox G, Harris AL, Jackson DG. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer. Cancer Research. 62: 1315-20. PMID 11888898  0.488
2002 Griffiths JR, McSheehy PMJ, Robinson SP, Troy H, Chung YL, Leek RD, Williams KJ, Stratford IJ, Harris AL, Stubbs M. Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1β (HIF-1β): Evidence of an anabolic role for the HIF-1 pathway Cancer Research. 62: 688-695. PMID 11830521  0.463
2002 Kelly CE, Leek RD, Byrne HM, Cox SM, Harris AL, Lewis CE. Modelling macrophage infiltration into avascular tumours Journal of Theoretical Medicine. 4: 21-38. DOI: 10.1080/10273660290015242  0.306
2001 Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 3660-8. PMID 11504747 DOI: 10.1200/Jco.2001.19.16.3660  0.445
2000 Leek RD, Hunt NC, Landers RJ, Lewis CE, Royds JA, Harris AL. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. The Journal of Pathology. 190: 430-6. PMID 10699991 DOI: 10.1002/(SICI)1096-9896(200003)190:4<430::AID-PATH538>3.0.CO;2-6  0.525
2000 Fox SB, Gatter KC, Leek RD, Harris AL, Chew KL, Mayall BH, Moore DH. More about: Tumor angiogenesis as a prognostic assay for invasive ductal breast carcinoma. Journal of the National Cancer Institute. 92: 161-2. PMID 10639519 DOI: 10.1093/jnci/92.2.161  0.605
1999 Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. British Journal of Cancer. 79: 991-5. PMID 10070902 DOI: 10.1038/sj.bjc.6690158  0.464
1999 Ellis MJ, Jenkins S, Hanfelt J, Redington ME, Taylor M, Leek R, Siddle K, Harris A. Insulin-like growth factors in human breast cancer. Breast Cancer Research and Treatment. 52: 175-84. PMID 10066081 DOI: 10.1023/A:1006127621512  0.441
1998 Zhang L, Scott PA, Turley H, Leek R, Lewis CE, Gatter KC, Harris AL, Mackenzie IZ, Rees MC, Bicknell R. Validation of anti-vascular endothelial growth factor (anti-VEGF) antibodies for immunohistochemical localization of VEGF in tissue sections: expression of VEGF in the human endometrium. The Journal of Pathology. 185: 402-8. PMID 9828839 DOI: 10.1002/(SICI)1096-9896(199808)185:4<402::AID-PATH112>3.0.CO;2-Y  0.65
1998 Leek RD, Landers R, Fox SB, Ng F, Harris AL, Lewis CE. Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma. British Journal of Cancer. 77: 2246-51. PMID 9649140 DOI: 10.1038/bjc.1998.373  0.611
1997 Fox SB, Leek RD, Bliss J, Mansi JL, Gusterson B, Gatter KC, Harris AL. Association of tumor angiogenesis with bone marrow micrometastases in breast cancer patients. Journal of the National Cancer Institute. 89: 1044-9. PMID 9230886 DOI: 10.1093/JNCI/89.14.1044  0.624
1997 Barbareschi M, Caffo O, Veronese S, Leek RD, Fina P, Fox S, Bonzanini M, Girlando S, Morelli L, Eccher C, Pezzella F, Doglioni C, Dalla Palma P, Harris A. Bcl-2 and p53 expression in node-negative breast carcinoma: a study with long-term follow-up. Human Pathology. 27: 1149-55. PMID 8912823 DOI: 10.1016/S0046-8177(96)90307-X  0.684
1996 Kaklamanis L, Koukourakis MI, Leek R, Giatromanolaki A, Ritter M, Whitehouse R, Gatter KC, Harris AL. Loss of interleukin 4 receptor-associated molecule gp200-MR6 in human breast cancer: prognostic significance. British Journal of Cancer. 74: 1627-31. PMID 8932345 DOI: 10.1038/bjc.1996.599  0.593
1996 Barbareschi M, Caffo O, Doglioni C, Fina P, Marchetti A, Buttitta F, Leek R, Morelli L, Leonardi E, Bevilacqua G, Dalla Palma P, Harris AL. p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival. British Journal of Cancer. 74: 208-15. PMID 8688323 DOI: 10.1038/bjc.1996.339  0.441
1996 Fox SB, Leek RD, Weekes MP, Whitehouse RM, Gatter KC, Harris AL. Quantitation and prognostic value of breast cancer angiogenesis: comparison of microvessel density, Chalkley count, and computer image analysis. The Journal of Pathology. 177: 275-83. PMID 8551390 DOI: 10.1002/PATH.1711770310  0.573
1996 Fox SB, Turner GD, Leek RD, Whitehouse RM, Gatter KC, Harris AL. The prognostic value of quantitative angiogenesis in breast cancer and role of adhesion molecule expression in tumor endothelium. Breast Cancer Research and Treatment. 36: 219-26. PMID 8534869 DOI: 10.1007/BF00666042  0.587
1995 Newby JC, A'Hern RP, Leek RD, Smith IE, Harris AL, Dowsett M. Immunohistochemical assay for epidermal growth factor receptor on paraffin-embedded sections: validation against ligand-binding assay and clinical relevance in breast cancer. British Journal of Cancer. 71: 1237-42. PMID 7779717 DOI: 10.1038/bjc.1995.239  0.429
1995 Harris AL, Fox S, Leek R, Zhang H, Scott P, Bicknell R, Gatter K. Breast cancer angiogenesis: therapy target and prognostic factor. European Journal of Cancer (Oxford, England : 1990). 831-2. PMID 7543767 DOI: 10.1016/0959-8049(95)00129-7  0.58
1995 Lewis CE, Leek R, Harris A, McGee JO. Cytokine regulation of angiogenesis in breast cancer: the role of tumor-associated macrophages. Journal of Leukocyte Biology. 57: 747-51. PMID 7539028 DOI: 10.1002/jlb.57.5.747  0.53
1995 Macaulay VM, Fox SB, Zhang H, Whitehouse RM, Leek RD, Gatter KC, Bicknell R, Harris AL. Breast cancer angiogenesis and tamoxifen resistance Endocrine Related Cancer. 2: 97-103. DOI: 10.1677/erc.0.0020097  0.57
1995 Caffo O, Barbareschi M, Veronese S, Pezzella F, Leek R, Fox S, Harris A, Dalla Palma P. 686 BCL2 expression in node-negative breast carcinoma: A study on a series of 190 cases with long-term follow-up European Journal of Cancer. 31: S143. DOI: 10.1016/0959-8049(95)95936-Z  0.669
1994 Leek RD, Kaklamanis L, Pezzella F, Gatter KC, Harris AL. bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer. British Journal of Cancer. 69: 135-9. PMID 8286195 DOI: 10.1038/bjc.1994.22  0.652
1994 Harris AL, Fox S, Bicknell R, Leek R, Relf M, LeJeune S, Kaklamanis L. Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer. Cancer. 74: 1021-5. PMID 8039135 DOI: 10.1002/1097-0142(19940801)74:3+<1021::AID-CNCR2820741508>3.0.CO;2-1  0.635
1994 Dixon J, Kaklamanis L, Turley H, Hickson ID, Leek RD, Harris AL, Gatter KC. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. Journal of Clinical Pathology. 47: 43-7. PMID 7907609 DOI: 10.1136/jcp.47.1.43  0.587
1994 Leek RD, Harris AL, Lewis CE. Cytokine networks in solid human tumors: regulation of angiogenesis. Journal of Leukocyte Biology. 56: 423-35. PMID 7523556 DOI: 10.1002/jlb.56.4.423  0.47
1994 Fox SB, Leek RD, Smith K, Hollyer J, Greenall M, Harris AL. Tumor angiogenesis in node-negative breast carcinomas--relationship with epidermal growth factor receptor, estrogen receptor, and survival. Breast Cancer Research and Treatment. 29: 109-116. PMID 7517221 DOI: 10.1007/Bf00666186  0.636
1994 Lewis C, Leek R, Harris A, McGee J. Cytokine regulation of angiogenesis in breast tumours Cytokine. 6: 581. DOI: 10.1016/1043-4666(94)90329-8  0.439
1992 Horak ER, Leek R, Klenk N, LeJeune S, Smith K, Stuart N, Greenall M, Stepniewska K, Harris AL. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet (London, England). 340: 1120-4. PMID 1279332 DOI: 10.1016/0140-6736(92)93150-L  0.461
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