Year |
Citation |
Score |
2020 |
Knowles HJ. Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function. Scientific Reports. 10: 21072. PMID 33273561 DOI: 10.1038/s41598-020-78003-z |
0.3 |
|
2017 |
Knowles HJ. Multiple Roles of Angiopoietin-Like 4 in Osteolytic Disease. Frontiers in Endocrinology. 8: 80. PMID 28458654 DOI: 10.3389/fendo.2017.00080 |
0.301 |
|
2017 |
Hulley PA, Bishop T, Vernet A, Schneider JE, Edwards JR, Athanasou NA, Knowles HJ. Hypoxia-Inducible Factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2. The Journal of Pathology. PMID 28418093 DOI: 10.1002/path.4906 |
0.362 |
|
2017 |
Knowles HJ. Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone. Calcified Tissue International. 100: 382-391. PMID 28097375 DOI: 10.1007/s00223-016-0228-1 |
0.327 |
|
2012 |
Taylor RM, Kashima TG, Knowles HJ, Athanasou NA. VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 1398-406. PMID 22906984 DOI: 10.1038/labinvest.2012.108 |
0.315 |
|
2011 |
Taylor R, Knowles HJ, Athanasou NA. Ewing sarcoma cells express RANKL and support osteoclastogenesis. The Journal of Pathology. 225: 195-202. PMID 21547906 DOI: 10.1002/path.2869 |
0.333 |
|
2010 |
Knowles HJ, Cleton-Jansen AM, Korsching E, Athanasou NA. Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4648-59. PMID 20667978 DOI: 10.1096/Fj.10-162230 |
0.377 |
|
2010 |
Knowles HJ, Schaefer KL, Dirksen U, Athanasou NA. Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor. Bmc Cancer. 10: 372. PMID 20637078 DOI: 10.1186/1471-2407-10-372 |
0.441 |
|
2010 |
Benson RT, McDonnell SM, Knowles HJ, Rees JL, Carr AJ, Hulley PA. Tendinopathy and tears of the rotator cuff are associated with hypoxia and apoptosis. The Journal of Bone and Joint Surgery. British Volume. 92: 448-53. PMID 20190320 DOI: 10.1302/0301-620X.92B3.23074 |
0.374 |
|
2010 |
Knowles H, Cleton-Jansen A, Korsching E, Athanasou N. Hypoxia-Inducible Factor (HIF) regulates Osteoclast-Mediated Bone Resorption via Angiopoietin-like 4 (ANGPTL4) Bone. 46. DOI: 10.1016/J.Bone.2010.01.151 |
0.331 |
|
2009 |
Knowles HJ, Athanasou NA. Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis. The Journal of Pathology. 218: 256-64. PMID 19291710 DOI: 10.1002/path.2534 |
0.354 |
|
2009 |
Knowles HJ, Athanasou NA. Canonical and non-canonical pathways of osteoclast formation. Histology and Histopathology. 24: 337-46. PMID 19130404 DOI: 10.14670/HH-24.337 |
0.304 |
|
2008 |
Knowles HJ, Athanasou NA. Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF. The Journal of Pathology. 215: 56-66. PMID 18283716 DOI: 10.1002/path.2319 |
0.549 |
|
2007 |
Knowles HJ, Harris AL. Macrophages and the hypoxic tumour microenvironment. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4298-314. PMID 17485376 DOI: 10.2741/2389 |
0.451 |
|
2006 |
Knowles HJ, Mole DR, Ratcliffe PJ, Harris AL. Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1. Cancer Research. 66: 2600-7. PMID 16510578 DOI: 10.1158/0008-5472.Can-05-2351 |
0.619 |
|
2006 |
Knowles HJ, te Poele RH, Te Poole R, Workman P, Harris AL. Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways. Biochemical Pharmacology. 71: 646-56. PMID 16386710 DOI: 10.1016/j.bcp.2005.11.019 |
0.492 |
|
2004 |
Knowles HJ, Tian YM, Mole DR, Harris AL. Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circulation Research. 95: 162-9. PMID 15192023 DOI: 10.1161/01.RES.0000134924.89412.70 |
0.542 |
|
2004 |
Knowles H, Leek R, Harris AL. Macrophage infiltration and angiogenesis in human malignancy. Novartis Foundation Symposium. 256: 189-200; discussion . PMID 15027491 |
0.574 |
|
2003 |
Knowles HJ, Raval RR, Harris AL, Ratcliffe PJ. Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Research. 63: 1764-8. PMID 12702559 |
0.538 |
|
2001 |
Knowles HJ, Harris AL. Hypoxia and tumorigenesis Breast Cancer Research. 3: 318-322. PMID 11597321 DOI: 10.1186/bcr314 |
0.526 |
|
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