Helen Turley - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. PMID 28445154 DOI: 10.18632/oncotarget.16969  0.801
2016 Siriwardana PN, Luong TV, Watkins J, Turley H, Ghazaley M, Gatter K, Harris AL, Hochhauser D, Davidson BR. Biological and Prognostic Significance of the Morphological Types and Vascular Patterns in Colorectal Liver Metastases (CRLM): Looking Beyond the Tumor Margin. Medicine. 95: e2924. PMID 26937938 DOI: 10.1097/MD.0000000000002924  0.515
2016 Tan K, Haider S, Zois C, Turley H, Leek R, Harris A, Buffa F, Acuto O, Pezzella F. NUB1 protein regulates cullins and E3 ligases in estrogen receptor negative breast cancers European Journal of Cancer. 61: S190. DOI: 10.1016/S0959-8049(16)61672-6  0.696
2016 Siriwardana P, Luong T, Watkins J, Turley H, Ong W, Gatter K, Hochhauser D, Harris A, Davidson B. Ten-year follow up case-control study of the effect of portal vein embolisation on the survival of patients with colorectal liver metastases; the hypoxia factor influence Hpb. 18: e3. DOI: 10.1016/J.HPB.2016.02.014  0.35
2015 Fan SJ, Snell C, Turley H, Li JL, McCormick R, Perera SM, Heublein S, Kazi S, Azad A, Wilson C, Harris AL, Goberdhan DC. PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. Oncogene. PMID 26434594 DOI: 10.1038/onc.2015.363  0.434
2015 Bazzola L, Foroni C, Andreis D, Zanoni V, R Cappelletti M, Allevi G, Aguggini S, Strina C, Milani M, Venturini S, Ferrozzi F, Giardini R, Bertoni R, Turley H, Gatter K, et al. Combination of letrozole, metronomic cyclophosphamide and sorafenib is well-tolerated and shows activity in patients with primary breast cancer. British Journal of Cancer. 112: 52-60. PMID 25461806 DOI: 10.1038/bjc.2014.563  0.773
2015 Stevens D, Verrill C, Bryant R, McKee C, Turley H, Fan S, Perera S, Wilson C, Harris AL, Hamdy FC, Goberdhan DC. MP55-12 THE PROTON-ASSISTED AMINO ACID TRANSPORTER 4 (PAT4/SLC36A4) IS UP-REGULATED IN PROSTATE CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2055  0.392
2014 Kato T, Pezzella F, Steers G, Campo L, Leek RD, Turley H, Kameoka S, Nishikawa T, Harris AL, Gatter KC, Fox S. Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer. International Journal of Clinical and Experimental Pathology. 7: 7967-78. PMID 25550840  0.776
2014 Adighibe O, Turley H, Leek R, Harris A, Coutts AS, La Thangue N, Gatter K, Pezzella F. JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues. Virchows Archiv : An International Journal of Pathology. 465: 715-22. PMID 25280461 DOI: 10.1007/s00428-014-1660-0  0.778
2014 Feldinger K, Generali D, Kramer-Marek G, Gijsen M, Ng TB, Wong JH, Strina C, Cappelletti M, Andreis D, Li JL, Bridges E, Turley H, Leek R, Roxanis I, Capala J, et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget. 5: 6633-46. PMID 24952873  0.778
2014 Agorreta J, Hu J, Liu D, Delia D, Turley H, Ferguson DJ, Iborra F, Pajares MJ, Larrayoz M, Zudaire I, Pio R, Montuenga LM, Harris AL, Gatter K, Pezzella F. TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Molecular Cancer Research : McR. 12: 660-9. PMID 24567527 DOI: 10.1158/1541-7786.MCR-13-0481  0.619
2014 Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours. Plos One. 9: e88955. PMID 24563687 DOI: 10.1371/Journal.Pone.0088955  0.815
2014 Abdulla Z, Turley H, Gatter K, Pezzella F. Immunohistological recognition of cyclin D1 expression by non-lymphoid cells among lymphoid neoplastic cells. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 122: 183-91. PMID 23758159 DOI: 10.1111/apm.12123  0.536
2014 Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Expression of proline-hydroxylated HIF-1α predicts poorer overall survival in primary breast cancer. Plos One. DOI: 10.1371/Journal.Pone.0088955.G005  0.781
2014 Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Li JL, Harris AL. Functional comparison of Notch ligands in tumour angiogenesis Asian Pacific Journal of Tropical Disease. 4: 229. DOI: 10.1016/S2222-1808(14)60523-5  0.775
2013 Nikitenko LL, Leek R, Henderson S, Pillay N, Turley H, Generali D, Gunningham S, Morrin HR, Pellagatti A, Rees MC, Harris AL, Fox SB. The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5740-8. PMID 23969937 DOI: 10.1158/1078-0432.CCR-13-1712  0.794
2013 Blick C, Ramachandran A, Wigfield S, McCormick R, Jubb A, Buffa FM, Turley H, Knowles MA, Cranston D, Catto J, Harris AL. Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer. British Journal of Cancer. 109: 50-9. PMID 23778527 DOI: 10.1038/bjc.2013.240  0.786
2013 Kashima TG, Turley H, Dongre A, Pezzella F, Athanasou NA. Diagnostic utility of aP2/FABP4 expression in soft tissue tumours. Virchows Archiv : An International Journal of Pathology. 462: 465-72. PMID 23511993 DOI: 10.1007/s00428-013-1392-6  0.545
2013 Kumar K, Wigfield S, Gee HE, Devlin CM, Singleton D, Li JL, Buffa F, Huffman M, Sinn AL, Silver J, Turley H, Leek R, Harris AL, Ivan M. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine (Berlin, Germany). 91: 749-58. PMID 23361368 DOI: 10.1007/s00109-013-0996-2  0.778
2013 McIntyre A, Hulikova A, Ledaki I, Seden P, Turley H, Jones D, Russell A, Swietach P, Harris AL. Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth. Cancer Research. 73: 4053-4053. DOI: 10.1158/1538-7445.Am2013-4053  0.811
2012 Favaro E, Bensaad K, Chong MG, Tennant DA, Ferguson DJ, Snell C, Steers G, Turley H, Li JL, Günther UL, Buffa FM, McIntyre A, Harris AL. Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells. Cell Metabolism. 16: 751-64. PMID 23177934 DOI: 10.1016/j.cmet.2012.10.017  0.796
2012 Biswas S, Charlesworth PJ, Turner GD, Leek R, Thamboo PT, Campo L, Turley H, Dildey P, Protheroe A, Cranston D, Gatter KC, Pezzella F, Harris AL. CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC. Carcinogenesis. 33: 1717-25. PMID 22777959 DOI: 10.1093/carcin/bgs222  0.818
2012 McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877  0.8
2012 Jubb AM, Browning L, Campo L, Turley H, Steers G, Thurston G, Harris AL, Ansorge O. Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma. Histopathology. 60: 740-7. PMID 22296176 DOI: 10.1111/j.1365-2559.2011.04138.x  0.73
2012 Mehta S, Hughes NP, Jubb AM, Turley H, Han C, Li SP, Taylor NJ, Padhani AR, Adams RF, Makris A, Harris AL. Early changes in angiogenesis and hypoxia following bevacizumab therapy in primary breast cancer. Journal of Clinical Oncology. 30: 1066-1066. DOI: 10.1200/JCO.2012.30.15_SUPPL.1066  0.718
2011 Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704  0.794
2011 Ong CC, Jubb AM, Haverty PM, Zhou W, Tran V, Truong T, Turley H, O'Brien T, Vucic D, Harris AL, Belvin M, Friedman LS, Blackwood EM, Koeppen H, Hoeflich KP. Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 7177-82. PMID 21482786 DOI: 10.1073/Pnas.1103350108  0.71
2011 Shaida N, Chan P, Turley H, Jones CM, Kanga S, Ritchie RW, Malone PR, Harris AL, Fox SB. Nuclear localization of factor inhibitor hypoxia-inducible factor in prostate cancer is associated with poor prognosis. The Journal of Urology. 185: 1513-8. PMID 21334674 DOI: 10.1016/j.juro.2010.12.001  0.599
2010 Yang J, Jubb AM, Pike L, Buffa FM, Turley H, Baban D, Leek R, Gatter KC, Ragoussis J, Harris AL. The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Research. 70: 6456-66. PMID 20682797 DOI: 10.1158/0008-5472.CAN-10-0413  0.802
2010 Biswas S, Troy H, Leek R, Chung YL, Li JL, Raval RR, Turley H, Gatter K, Pezzella F, Griffiths JR, Stubbs M, Harris AL. Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. Journal of Oncology. 2010: 757908. PMID 20652061 DOI: 10.1155/2010/757908  0.803
2010 Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116: 2385-94. PMID 20558614 DOI: 10.1182/blood-2009-08-239228  0.791
2010 Gossage L, Zaitoun A, Fareed KR, Turley H, Aloysius M, Lobo DN, Harris AL, Madhusudan S. Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer. Histopathology. 56: 908-20. PMID 20497244 DOI: 10.1111/j.1365-2559.2010.03566.x  0.46
2010 Jubb AM, Soilleux EJ, Turley H, Steers G, Parker A, Low I, Blades J, Li JL, Allen P, Leek R, Noguera-Troise I, Gatter KC, Thurston G, Harris AL. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. The American Journal of Pathology. 176: 2019-28. PMID 20167860 DOI: 10.2353/ajpath.2010.090908  0.819
2010 Oon C, Li J, Sainson R, Sheldon H, Turley H, Leek R, Harris A. 360 Role of DLL4 and JAG1 in tumour angiogenesis European Journal of Cancer Supplements. 8: 92. DOI: 10.1016/S1359-6349(10)71161-7  0.791
2009 Yang J, Ledaki I, Turley H, Gatter KC, Montero JC, Li JL, Harris AL. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Annals of the New York Academy of Sciences. 1177: 185-97. PMID 19845621 DOI: 10.1111/j.1749-6632.2009.05027.x  0.759
2009 Jubb AM, Turley H, Moeller HC, Steers G, Han C, Li JL, Leek R, Tan EY, Singh B, Mortensen NJ, Noguera-Troise I, Pezzella F, Gatter KC, Thurston G, Fox SB, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. British Journal of Cancer. 101: 1749-57. PMID 19844231 DOI: 10.1038/sj.bjc.6605368  0.845
2009 Turley H, Steers G, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Corrigendum. Histopathology. 55: 463-4. PMID 19817897 DOI: 10.1111/j.1365-2559.2009.03412.x  0.767
2009 Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. British Journal of Cancer. 100: 1666-73. PMID 19436307 DOI: 10.1038/sj.bjc.6605026  0.448
2009 Martinez JC, Müller MM, Turley H, Steers G, Choteau L, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues. Histopathology. 54: 598-606. PMID 19413639 DOI: 10.1111/j.1365-2559.2009.03279.x  0.816
2009 Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, et al. The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy. British Journal of Cancer. 100: 405-11. PMID 19165203 DOI: 10.1038/sj.bjc.6604844  0.728
2009 Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer. Pathology, Research and Practice. 205: 1-9. PMID 19008051 DOI: 10.1016/j.prp.2008.08.008  0.397
2009 Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JMA, Guenther T. Erratum: Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis British Journal of Cancer. 101: 742-742. DOI: 10.1038/sj.bjc.6605242  0.404
2009 Jensen H, Nordsmark M, Donskov F, Marcussen N, Turley H, Gatter K, Harris A, von der Maase H. 7103 Baseline and on-treatment expression of HIF-1a, HIF-2a and CAIX in patients with metastatic renal cell carcinoma European Journal of Cancer Supplements. 7: 423. DOI: 10.1016/S1359-6349(09)71436-3  0.356
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins. Leukemia & Lymphoma. 49: 2181-6. PMID 19021062 DOI: 10.1080/10428190802450629  0.74
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematological Oncology. 26: 219-24. PMID 18461646 DOI: 10.1002/hon.861  0.757
2008 Jiang X, Tian F, Du Y, Copeland NG, Jenkins NA, Tessarollo L, Wu X, Pan H, Hu XZ, Xu K, Kenney H, Egan SE, Turley H, Harris AL, Marini AM, et al. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1118-30. PMID 18234890 DOI: 10.1523/Jneurosci.2262-07.2008  0.316
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Turley H, Sivridis E, Bouros D, Bougioukas G, Harris AL, Gatter KC. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway. Cancer Letters. 262: 87-93. PMID 18187257 DOI: 10.1016/j.canlet.2007.11.041  0.727
2008 Shaida N, Launchbury R, Boddy JL, Jones C, Campo L, Turley H, Kanga S, Banham AH, Malone PR, Harris AL, Fox SB. Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. The Prostate. 68: 336-43. PMID 18163427 DOI: 10.1002/pros.20707  0.82
2007 Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer. Breast Cancer Research : Bcr. 9: R89. PMID 18096060 DOI: 10.1186/bcr1838  0.749
2007 Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL. Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Research. 67: 11244-53. PMID 18056450 DOI: 10.1158/0008-5472.CAN-07-0969  0.798
2007 Kato T, Steers G, Campo L, Roberts H, Leek RD, Turley H, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Harris AL, Gatter KC, Pezzella F. Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. British Journal of Cancer. 97: 1277-86. PMID 17923874 DOI: 10.1038/sj.bjc.6604015  0.73
2007 Giatromanolaki A, Koukourakis MI, Sivridis E, Chlouverakis G, Vourvouhaki E, Turley H, Harris AL, Gatter KC. Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer. European Journal of Clinical Investigation. 37: 878-86. PMID 17883421 DOI: 10.1111/j.1365-2362.2007.01866.x  0.61
2007 Ord JJ, Agrawal S, Thamboo TP, Roberts I, Campo L, Turley H, Han C, Fawcett DW, Kulkarni RP, Cranston D, Harris AL. An investigation into the prognostic significance of necrosis and hypoxia in high grade and invasive bladder cancer. The Journal of Urology. 178: 677-82. PMID 17574616 DOI: 10.1016/j.juro.2007.03.112  0.812
2007 Gunningham SP, Currie MJ, Morrin HR, Tan EY, Turley H, Dachs GU, Watson AI, Frampton C, Robinson BA, Fox SB. The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers. The Journal of Pathology. 212: 335-44. PMID 17487938 DOI: 10.1002/path.2174  0.555
2007 Banham AH, Boddy J, Launchbury R, Han C, Turley H, Malone PR, Harris AL, Fox SB. Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia. The Prostate. 67: 1091-8. PMID 17477366 DOI: 10.1002/pros.20583  0.817
2007 Winter SC, Buffa FM, Silva P, Miller C, Valentine HR, Turley H, Shah KA, Cox GJ, Corbridge RJ, Homer JJ, Musgrove B, Slevin N, Sloan P, Price P, West CM, et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Research. 67: 3441-9. PMID 17409455 DOI: 10.1158/0008-5472.CAN-06-3322  0.679
2007 Sington J, Giatromanolaki A, Campo L, Turley H, Pezzella F, Gatter KC. BNIP3 expression in follicular lymphoma. Histopathology. 50: 555-60. PMID 17394490 DOI: 10.1111/j.1365-2559.2007.02657.x  0.541
2007 Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. BNIP3 as a progression marker in primary human breast cancer; opposing functions in in situ versus invasive cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 467-74. PMID 17255267 DOI: 10.1158/1078-0432.CCR-06-1466  0.743
2006 Nikitenko LL, Cross T, Campo L, Turley H, Leek R, Manek S, Bicknell R, Rees MC. Expression of terminally glycosylated calcitonin receptor-like receptor in uterine leiomyoma: endothelial phenotype and association with microvascular density. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5648-58. PMID 17020966 DOI: 10.1158/1078-0432.CCR-06-0852  0.628
2006 Giatromanolaki A, Sivridis E, Gatter KC, Turley H, Harris AL, Koukourakis MI. Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis. Gynecologic Oncology. 103: 912-8. PMID 16837029 DOI: 10.1016/j.ygyno.2006.05.043  0.653
2006 Winter SC, Shah KA, Han C, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. The relation between hypoxia-inducible factor (HIF)=1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer Cancer. 107: 757-766. PMID 16826581 DOI: 10.1002/cncr.21983  0.765
2006 Bacon AL, Fox S, Turley H, Harris AL. Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. Oncogene. 26: 132-41. PMID 16799636 DOI: 10.1038/sj.onc.1209761  0.807
2006 Giatromanolaki A, Koukourakis MI, Turley H, Sivridis E, Harris AL, Gatter KC. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 701-7. PMID 16557278 DOI: 10.1038/modpathol.3800579  0.681
2006 Soilleux EJ, Turley H, Tian YM, Pugh CW, Gatter KC, Harris AL. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 47: 602-10. PMID 16324198 DOI: 10.1111/j.1365-2559.2005.02280.x  0.468
2005 Boddy JL, Fox SB, Han C, Campo L, Turley H, Kanga S, Malone PR, Harris AL. The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer Clinical Cancer Research. 11: 7658-7663. PMID 16278385 DOI: 10.1158/1078-0432.CCR-05-0460  0.805
2005 Winter SC, Shah KA, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma Clinical Cancer Research. 11: 7614-7620. PMID 16278379 DOI: 10.1158/1078-0432.CCR-05-1097  0.78
2005 Van den Eynden GG, Van der Auwera I, Van Laere SJ, Colpaert CG, Turley H, Harris AL, van Dam P, Dirix LY, Vermeulen PB, Van Marck EA. Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer. British Journal of Cancer. 93: 1128-36. PMID 16251878 DOI: 10.1038/Sj.Bjc.6602828  0.468
2005 Zhang Y, Pillai G, Gatter K, Blázquez C, Turley H, Pezzella F, Watt SM. Expression and cellular localization of vascular endothelial growth factor A and its receptors in acute and chronic leukemias: an immunohistochemical study. Human Pathology. 36: 797-805. PMID 16084950 DOI: 10.1016/j.humpath.2005.05.015  0.599
2005 Daniels RA, Turley H, Kimberley FC, Liu XS, Mongkolsapaya J, Ch'en P, Xu XN, Jin B, Pezzella F, Screaton GR. Expression of TRAIL and TRAIL receptors in normal and malignant tissues Cell Research. 15: 430-438. PMID 15987601 DOI: 10.1038/sj.cr.7290311  0.604
2005 Couvelard A, O'Toole D, Leek R, Turley H, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas. Histopathology. 46: 668-76. PMID 15910598 DOI: 10.1111/j.1365-2559.2005.02160.x  0.765
2005 Campo L, Turley H, Han C, Pezzella F, Gatter KC, Harris AL, Fox SB. Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival. The Journal of Pathology. 205: 585-91. PMID 15776477 DOI: 10.1002/path.1740  0.729
2005 Pillai G, Cook N, Turley H, Leek RD, Blasquez C, Pezzella F, Harris AL, Gatter KC. The expression and cellular localization of phosphorylated VEGFR2 in lymphoma and non-neoplastic lymphadenopathy: an immunohistochemical study. Histopathology. 46: 209-16. PMID 15693894 DOI: 10.1111/j.1365-2559.2005.02081.x  0.758
2005 Couvelard A, O'Toole D, Turley H, Leek R, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. British Journal of Cancer. 92: 94-101. PMID 15558070 DOI: 10.1038/sj.bjc.6602245  0.792
2004 Van der Auwera I, Van Laere SJ, Van den Eynden GG, Benoy I, van Dam P, Colpaert CG, Fox SB, Turley H, Harris AL, Van Marck EA, Vermeulen PB, Dirix LY. Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7965-71. PMID 15585631 DOI: 10.1158/1078-0432.Ccr-04-0063  0.55
2004 Fox SB, Bragança J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S, Harris AL. CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. Cancer Research. 64: 6075-81. PMID 15342390 DOI: 10.1158/0008-5472.Can-04-0708  0.649
2004 Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC, Fox SB. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. British Journal of Cancer. 91: 954-8. PMID 15328513 DOI: 10.1038/sj.bjc.6602059  0.652
2004 Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. The Journal of Biological Chemistry. 279: 42719-25. PMID 15302861 DOI: 10.1074/Jbc.M406713200  0.592
2004 Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. The Journal of Biological Chemistry. 279: 38458-65. PMID 15247232 DOI: 10.1074/Jbc.M406026200  0.733
2004 Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. The Journal of Pathology. 203: 808-13. PMID 15221940 DOI: 10.1002/path.1585  0.669
2004 Fox SB, Turley H, Cheale M, Blázquez C, Roberts H, James N, Cook N, Harris A, Gatter K. Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus. The Journal of Pathology. 202: 313-20. PMID 14991896 DOI: 10.1002/path.1520  0.603
2004 Stewart M, Turley H, Cook N, Pezzella F, Pillai G, Ogilvie D, Cartlidge S, Paterson D, Copley C, Kendrew J, Barnes C, Harris AL, Gatter KC. The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study. Histopathology. 43: 33-9. PMID 12823710 DOI: 10.1046/j.1365-2559.2003.01644.x  0.647
2004 Ord JJ, Cranston D, Harris AL, Campo L, Turley H, Allen P, Fox S, Davies DR. 773: C-KIT and CK7 Immunohistochemistry in the Differential Diagnosis of Renal Cell Carcinoma, A Study of 111 Cases Journal of Urology. 171: 205-205. DOI: 10.1016/s0022-5347(18)38022-4  0.487
2003 Braybrooke JP, Levitt NC, Joel S, Davis T, Madhusudan S, Turley H, Wilner S, Harris AL, Talbot DC. Pharmacokinetic study of cisplatin and infusional etoposide phosphate in advanced breast cancer with correlation of response to topoisomerase IIalpha expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4682-8. PMID 14581337  0.42
2003 Kaklamanis L, Kakolyris S, Turley H, Koukourakis M, Biddolph S, Gatter KC, Harris AL. Neoplastic stroma and epithelium show up-regulation of platelet-derived endothelial cell growth factor/thymidine phosphorylase in colorectal carcinomas but not adenomas. Angiogenesis. 2: 49-55. PMID 14517375 DOI: 10.1023/A:1009002426554  0.509
2003 Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. The Journal of Pathology. 200: 222-8. PMID 12754744 DOI: 10.1002/path.1330  0.741
2003 Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 473-82. PMID 12560438 DOI: 10.1200/JCO.2003.11.132  0.629
2003 Propper DJ, Chao D, Braybrooke JP, Bahl P, Thavasu P, Balkwill F, Turley H, Dobbs N, Gatter K, Talbot DC, Harris AL, Ganesan TS. Low-dose IFN-gamma induces tumor MHC expression in metastatic malignant melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 84-92. PMID 12538455  0.403
2002 Doussis-Anagnostopoulou IA, Talks KL, Turley H, Debnam P, Tan DC, Mariatos G, Gorgoulis V, Kittas C, Gatter KC. Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease. The Journal of Pathology. 197: 677-83. PMID 12210089 DOI: 10.1002/path.1151  0.745
2002 Hui EP, Chan AT, Pezzella F, Turley H, To KF, Poon TC, Zee B, Mo F, Teo PM, Huang DP, Gatter KC, Johnson PJ, Harris AL. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2595-604. PMID 12171890  0.672
2002 Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos C, Turley H, Talks K, Gatter KC, Harris AL. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 53: 1192-202. PMID 12128120 DOI: 10.1016/S0360-3016(02)02848-1  0.799
2002 Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, Millard P, Fuggle S, Harris AL. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Research. 62: 2493-7. PMID 11980639  0.709
2002 Stewart M, Talks K, Leek R, Turley H, Pezzella F, Harris A, Gatter K. Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma. Histopathology. 40: 253-60. PMID 11895491 DOI: 10.1046/j.1365-2559.2002.01357.x  0.82
2002 Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Research. 62: 1326-9. PMID 11888900  0.833
2001 Winters ZE, Hunt NC, Bradburn MJ, Royds JA, Turley H, Harris AL, Norbury CJ. Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis. European Journal of Cancer (Oxford, England : 1990). 37: 2405-12. PMID 11720835 DOI: 10.1016/S0959-8049(01)00327-6  0.427
2001 Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Talks K, Pezzella F, Gatter KC, Harris AL. Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. British Journal of Cancer. 85: 881-90. PMID 11556841 DOI: 10.1054/bjoc.2001.2018  0.828
2000 Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. The American Journal of Pathology. 157: 411-21. PMID 10934146 DOI: 10.1016/S0002-9440(10)64554-3  0.761
2000 Jones A, Fujiyama C, Turner K, Fuggle S, Cranston D, Turley H, Valtola R, Bicknell R, Harris AL. Angiogenesis and lymphangiogenesis in stage 1 germ cell tumours of the testis. Bju International. 86: 80-6. PMID 10886088 DOI: 10.1046/j.1464-410x.2000.00660.x  0.401
2000 Zhang HT, Scott PA, Morbidelli L, Peak S, Moore J, Turley H, Harris AL, Ziche M, Bicknell R. The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. British Journal of Cancer. 83: 63-8. PMID 10883669 DOI: 10.1054/bjoc.2000.1279  0.35
2000 O'Byrne KJ, Koukourakis MI, Giatromanolaki A, Cox G, Turley H, Steward WP, Gatter K, Harris AL. Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. British Journal of Cancer. 82: 1427-32. PMID 10780522 DOI: 10.1054/bjoc.1999.1129  0.556
2000 Koukourakis MI, Giatromanolaki A, Guddo F, Kaklamanis L, Vignola M, Kakolyris S, Turley H, Georgoulias V, Bonsignore G, Gatter KC, Harris AL. c-erbB-2 and episialin challenge host immune response by HLA class I expression in human non-small-cell lung cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 104-14. PMID 10687143 DOI: 10.1097/00002371-200001000-00013  0.534
1999 Turley H, Scott PA, Watts VM, Bicknell R, Harris AL, Gatter KC. Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. The Journal of Pathology. 186: 313-8. PMID 10211122 DOI: 10.1002/(SICI)1096-9896(1998110)186:3<313::AID-PATH188>3.0.CO;2-X  0.456
1998 Zhang L, Scott PA, Turley H, Leek R, Lewis CE, Gatter KC, Harris AL, Mackenzie IZ, Rees MC, Bicknell R. Validation of anti-vascular endothelial growth factor (anti-VEGF) antibodies for immunohistochemical localization of VEGF in tissue sections: expression of VEGF in the human endometrium. The Journal of Pathology. 185: 402-8. PMID 9828839 DOI: 10.1002/(SICI)1096-9896(199808)185:4<402::AID-PATH112>3.0.CO;2-Y  0.692
1998 Wiesener M, Turley H, Allen W, Willam C, Eckardt K, Talks K, Wood S, Gatter K, Harris A, Pugh C, Ratcliffe P, Maxwell P. Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α Blood. 92: 2260-2268. DOI: 10.1182/Blood.V92.7.2260.2260_2260_2268  0.746
1997 Turley H, Comley M, Houlbrook S, Nozaki N, Kikuchi A, Hickson ID, Gatter K, Harris AL. The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues. British Journal of Cancer. 75: 1340-6. PMID 9155056 DOI: 10.1038/bjc.1997.227  0.451
1997 Fox SB, Engels K, Comley M, Whitehouse RM, Turley H, Gatter KC, Harris AL. Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 8: 271-5. PMID 9137797 DOI: 10.1023/A:1008280110558  0.562
1997 Giatromanolaki A, Koukourakis MI, Comley M, Kaklamams L, Turley H, O'Byrne K, Harris AL, Gatter KC. Platelet-derived endothelial cell growth factor (thymidine phosphorylase) expression in lung cancer Journal of Pathology. 181: 196-199. PMID 9120725 DOI: 10.1002/(SICI)1096-9896(199702)181:2<196::AID-PATH763>3.0.CO;2-U  0.525
1996 Sandri M, Hochhauser D, Ayton P, Camplejohn R, Whitehouse R, Turley H, Gatter K, Hickson I, Harris A. Differential expression of the topoisomerase II alpha and beta genes in human breast cancers. British Journal of Cancer. 73: 1518-1524. PMID 8664122 DOI: 10.1038/Bjc.1996.286  0.433
1996 Fox SB, Westwood M, Moghaddam A, Comley M, Turley H, Whitehouse RM, Bicknell R, Gatter KC, Harris AL. The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium. British Journal of Cancer. 73: 275-80. PMID 8562330 DOI: 10.1038/bjc.1996.49  0.652
1995 Fox SB, Moghaddam A, Westwood M, Turley H, Bicknell R, Gatter KC, Harris AL. Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: an immunohistochemical study. The Journal of Pathology. 176: 183-90. PMID 7636628 DOI: 10.1002/path.1711760212  0.568
1995 Moghaddam A, Zhang HT, Fan TP, Hu DE, Lees VC, Turley H, Fox SB, Gatter KC, Harris AL, Bicknell R. Thymidine phosphorylase is angiogenic and promotes tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 92: 998-1002. PMID 7532308 DOI: 10.1073/pnas.92.4.998  0.619
1994 Pezzella F, Micklem K, Turley H, Pulford K, Jones M, Kocialkowski S, Delia D, Aiello A, Bicknell R, Smith K. Antibody for detecting p53 protein by immunohistochemistry in normal tissues. Journal of Clinical Pathology. 47: 592-6. PMID 8089212 DOI: 10.1136/jcp.47.7.592  0.509
1994 Dixon J, Kaklamanis L, Turley H, Hickson ID, Leek RD, Harris AL, Gatter KC. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. Journal of Clinical Pathology. 47: 43-7. PMID 7907609 DOI: 10.1136/jcp.47.1.43  0.621
1993 Pezzella F, Turley H, Kuzu I, Tungekar MF, Dunnill MS, Pierce CB, Harris A, Gatter KC, Mason DY. bcl-2 protein in non-small-cell lung carcinoma. The New England Journal of Medicine. 329: 690-4. PMID 8393963 DOI: 10.1056/NEJM199309023291003  0.553
1992 Pezzella F, Turley H, Kuzu I, Gatter KC, Mason DY, Harris A. Reversible p53 expression in lung cancer. Lancet (London, England). 340: 922. PMID 1357342 DOI: 10.1016/0140-6736(92)93342-K  0.537
Show low-probability matches.