| Year |
Citation |
Score |
| 2017 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. PMID 28445154 DOI: 10.18632/oncotarget.16969 |
0.801 |
|
| 2016 |
Siriwardana PN, Luong TV, Watkins J, Turley H, Ghazaley M, Gatter K, Harris AL, Hochhauser D, Davidson BR. Biological and Prognostic Significance of the Morphological Types and Vascular Patterns in Colorectal Liver Metastases (CRLM): Looking Beyond the Tumor Margin. Medicine. 95: e2924. PMID 26937938 DOI: 10.1097/MD.0000000000002924 |
0.514 |
|
| 2016 |
Tan K, Haider S, Zois C, Turley H, Leek R, Harris A, Buffa F, Acuto O, Pezzella F. NUB1 protein regulates cullins and E3 ligases in estrogen receptor negative breast cancers European Journal of Cancer. 61: S190. DOI: 10.1016/S0959-8049(16)61672-6 |
0.695 |
|
| 2016 |
Siriwardana P, Luong T, Watkins J, Turley H, Ong W, Gatter K, Hochhauser D, Harris A, Davidson B. Ten-year follow up case-control study of the effect of portal vein embolisation on the survival of patients with colorectal liver metastases; the hypoxia factor influence Hpb. 18: e3. DOI: 10.1016/J.HPB.2016.02.014 |
0.349 |
|
| 2015 |
Fan SJ, Snell C, Turley H, Li JL, McCormick R, Perera SM, Heublein S, Kazi S, Azad A, Wilson C, Harris AL, Goberdhan DC. PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. Oncogene. PMID 26434594 DOI: 10.1038/onc.2015.363 |
0.433 |
|
| 2015 |
Bazzola L, Foroni C, Andreis D, Zanoni V, R Cappelletti M, Allevi G, Aguggini S, Strina C, Milani M, Venturini S, Ferrozzi F, Giardini R, Bertoni R, Turley H, Gatter K, et al. Combination of letrozole, metronomic cyclophosphamide and sorafenib is well-tolerated and shows activity in patients with primary breast cancer. British Journal of Cancer. 112: 52-60. PMID 25461806 DOI: 10.1038/bjc.2014.563 |
0.768 |
|
| 2015 |
Stevens D, Verrill C, Bryant R, McKee C, Turley H, Fan S, Perera S, Wilson C, Harris AL, Hamdy FC, Goberdhan DC. MP55-12 THE PROTON-ASSISTED AMINO ACID TRANSPORTER 4 (PAT4/SLC36A4) IS UP-REGULATED IN PROSTATE CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2055 |
0.39 |
|
| 2014 |
Kato T, Pezzella F, Steers G, Campo L, Leek RD, Turley H, Kameoka S, Nishikawa T, Harris AL, Gatter KC, Fox S. Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer. International Journal of Clinical and Experimental Pathology. 7: 7967-78. PMID 25550840 |
0.774 |
|
| 2014 |
Adighibe O, Turley H, Leek R, Harris A, Coutts AS, La Thangue N, Gatter K, Pezzella F. JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues. Virchows Archiv : An International Journal of Pathology. 465: 715-22. PMID 25280461 DOI: 10.1007/s00428-014-1660-0 |
0.777 |
|
| 2014 |
Feldinger K, Generali D, Kramer-Marek G, Gijsen M, Ng TB, Wong JH, Strina C, Cappelletti M, Andreis D, Li JL, Bridges E, Turley H, Leek R, Roxanis I, Capala J, et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget. 5: 6633-46. PMID 24952873 |
0.778 |
|
| 2014 |
Agorreta J, Hu J, Liu D, Delia D, Turley H, Ferguson DJ, Iborra F, Pajares MJ, Larrayoz M, Zudaire I, Pio R, Montuenga LM, Harris AL, Gatter K, Pezzella F. TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Molecular Cancer Research : McR. 12: 660-9. PMID 24567527 DOI: 10.1158/1541-7786.MCR-13-0481 |
0.617 |
|
| 2014 |
Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours. Plos One. 9: e88955. PMID 24563687 DOI: 10.1371/Journal.Pone.0088955 |
0.81 |
|
| 2014 |
Abdulla Z, Turley H, Gatter K, Pezzella F. Immunohistological recognition of cyclin D1 expression by non-lymphoid cells among lymphoid neoplastic cells. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 122: 183-91. PMID 23758159 DOI: 10.1111/apm.12123 |
0.535 |
|
| 2014 |
Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Expression of proline-hydroxylated HIF-1α predicts poorer overall survival in primary breast cancer. Plos One. DOI: 10.1371/Journal.Pone.0088955.G005 |
0.776 |
|
| 2014 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Li JL, Harris AL. Functional comparison of Notch ligands in tumour angiogenesis Asian Pacific Journal of Tropical Disease. 4: 229. DOI: 10.1016/S2222-1808(14)60523-5 |
0.775 |
|
| 2013 |
Nikitenko LL, Leek R, Henderson S, Pillay N, Turley H, Generali D, Gunningham S, Morrin HR, Pellagatti A, Rees MC, Harris AL, Fox SB. The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5740-8. PMID 23969937 DOI: 10.1158/1078-0432.CCR-13-1712 |
0.791 |
|
| 2013 |
Blick C, Ramachandran A, Wigfield S, McCormick R, Jubb A, Buffa FM, Turley H, Knowles MA, Cranston D, Catto J, Harris AL. Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer. British Journal of Cancer. 109: 50-9. PMID 23778527 DOI: 10.1038/bjc.2013.240 |
0.786 |
|
| 2013 |
Kashima TG, Turley H, Dongre A, Pezzella F, Athanasou NA. Diagnostic utility of aP2/FABP4 expression in soft tissue tumours. Virchows Archiv : An International Journal of Pathology. 462: 465-72. PMID 23511993 DOI: 10.1007/s00428-013-1392-6 |
0.543 |
|
| 2013 |
Kumar K, Wigfield S, Gee HE, Devlin CM, Singleton D, Li JL, Buffa F, Huffman M, Sinn AL, Silver J, Turley H, Leek R, Harris AL, Ivan M. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine (Berlin, Germany). 91: 749-58. PMID 23361368 DOI: 10.1007/s00109-013-0996-2 |
0.778 |
|
| 2013 |
McIntyre A, Hulikova A, Ledaki I, Seden P, Turley H, Jones D, Russell A, Swietach P, Harris AL. Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth. Cancer Research. 73: 4053-4053. DOI: 10.1158/1538-7445.Am2013-4053 |
0.811 |
|
| 2012 |
Favaro E, Bensaad K, Chong MG, Tennant DA, Ferguson DJ, Snell C, Steers G, Turley H, Li JL, Günther UL, Buffa FM, McIntyre A, Harris AL. Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells. Cell Metabolism. 16: 751-64. PMID 23177934 DOI: 10.1016/j.cmet.2012.10.017 |
0.796 |
|
| 2012 |
Biswas S, Charlesworth PJ, Turner GD, Leek R, Thamboo PT, Campo L, Turley H, Dildey P, Protheroe A, Cranston D, Gatter KC, Pezzella F, Harris AL. CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC. Carcinogenesis. 33: 1717-25. PMID 22777959 DOI: 10.1093/carcin/bgs222 |
0.818 |
|
| 2012 |
McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877 |
0.799 |
|
| 2012 |
Jubb AM, Browning L, Campo L, Turley H, Steers G, Thurston G, Harris AL, Ansorge O. Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma. Histopathology. 60: 740-7. PMID 22296176 DOI: 10.1111/j.1365-2559.2011.04138.x |
0.73 |
|
| 2012 |
Mehta S, Hughes NP, Jubb AM, Turley H, Han C, Li SP, Taylor NJ, Padhani AR, Adams RF, Makris A, Harris AL. Early changes in angiogenesis and hypoxia following bevacizumab therapy in primary breast cancer. Journal of Clinical Oncology. 30: 1066-1066. DOI: 10.1200/JCO.2012.30.15_SUPPL.1066 |
0.718 |
|
| 2011 |
Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704 |
0.794 |
|
| 2011 |
Ong CC, Jubb AM, Haverty PM, Zhou W, Tran V, Truong T, Turley H, O'Brien T, Vucic D, Harris AL, Belvin M, Friedman LS, Blackwood EM, Koeppen H, Hoeflich KP. Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 7177-82. PMID 21482786 DOI: 10.1073/Pnas.1103350108 |
0.71 |
|
| 2011 |
Shaida N, Chan P, Turley H, Jones CM, Kanga S, Ritchie RW, Malone PR, Harris AL, Fox SB. Nuclear localization of factor inhibitor hypoxia-inducible factor in prostate cancer is associated with poor prognosis. The Journal of Urology. 185: 1513-8. PMID 21334674 DOI: 10.1016/j.juro.2010.12.001 |
0.596 |
|
| 2010 |
Yang J, Jubb AM, Pike L, Buffa FM, Turley H, Baban D, Leek R, Gatter KC, Ragoussis J, Harris AL. The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Research. 70: 6456-66. PMID 20682797 DOI: 10.1158/0008-5472.CAN-10-0413 |
0.803 |
|
| 2010 |
Biswas S, Troy H, Leek R, Chung YL, Li JL, Raval RR, Turley H, Gatter K, Pezzella F, Griffiths JR, Stubbs M, Harris AL. Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. Journal of Oncology. 2010: 757908. PMID 20652061 DOI: 10.1155/2010/757908 |
0.804 |
|
| 2010 |
Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116: 2385-94. PMID 20558614 DOI: 10.1182/blood-2009-08-239228 |
0.791 |
|
| 2010 |
Gossage L, Zaitoun A, Fareed KR, Turley H, Aloysius M, Lobo DN, Harris AL, Madhusudan S. Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer. Histopathology. 56: 908-20. PMID 20497244 DOI: 10.1111/j.1365-2559.2010.03566.x |
0.459 |
|
| 2010 |
Jubb AM, Soilleux EJ, Turley H, Steers G, Parker A, Low I, Blades J, Li JL, Allen P, Leek R, Noguera-Troise I, Gatter KC, Thurston G, Harris AL. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. The American Journal of Pathology. 176: 2019-28. PMID 20167860 DOI: 10.2353/ajpath.2010.090908 |
0.819 |
|
| 2010 |
Oon C, Li J, Sainson R, Sheldon H, Turley H, Leek R, Harris A. 360 Role of DLL4 and JAG1 in tumour angiogenesis European Journal of Cancer Supplements. 8: 92. DOI: 10.1016/S1359-6349(10)71161-7 |
0.791 |
|
| 2009 |
Yang J, Ledaki I, Turley H, Gatter KC, Montero JC, Li JL, Harris AL. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Annals of the New York Academy of Sciences. 1177: 185-97. PMID 19845621 DOI: 10.1111/j.1749-6632.2009.05027.x |
0.759 |
|
| 2009 |
Jubb AM, Turley H, Moeller HC, Steers G, Han C, Li JL, Leek R, Tan EY, Singh B, Mortensen NJ, Noguera-Troise I, Pezzella F, Gatter KC, Thurston G, Fox SB, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. British Journal of Cancer. 101: 1749-57. PMID 19844231 DOI: 10.1038/sj.bjc.6605368 |
0.845 |
|
| 2009 |
Turley H, Steers G, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Corrigendum. Histopathology. 55: 463-4. PMID 19817897 DOI: 10.1111/j.1365-2559.2009.03412.x |
0.767 |
|
| 2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. British Journal of Cancer. 100: 1666-73. PMID 19436307 DOI: 10.1038/sj.bjc.6605026 |
0.447 |
|
| 2009 |
Martinez JC, Müller MM, Turley H, Steers G, Choteau L, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues. Histopathology. 54: 598-606. PMID 19413639 DOI: 10.1111/j.1365-2559.2009.03279.x |
0.816 |
|
| 2009 |
Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, et al. The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy. British Journal of Cancer. 100: 405-11. PMID 19165203 DOI: 10.1038/sj.bjc.6604844 |
0.726 |
|
| 2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer. Pathology, Research and Practice. 205: 1-9. PMID 19008051 DOI: 10.1016/j.prp.2008.08.008 |
0.396 |
|
| 2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JMA, Guenther T. Erratum: Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis British Journal of Cancer. 101: 742-742. DOI: 10.1038/sj.bjc.6605242 |
0.403 |
|
| 2009 |
Jensen H, Nordsmark M, Donskov F, Marcussen N, Turley H, Gatter K, Harris A, von der Maase H. 7103 Baseline and on-treatment expression of HIF-1a, HIF-2a and CAIX in patients with metastatic renal cell carcinoma European Journal of Cancer Supplements. 7: 423. DOI: 10.1016/S1359-6349(09)71436-3 |
0.355 |
|
| 2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins. Leukemia & Lymphoma. 49: 2181-6. PMID 19021062 DOI: 10.1080/10428190802450629 |
0.738 |
|
| 2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematological Oncology. 26: 219-24. PMID 18461646 DOI: 10.1002/hon.861 |
0.755 |
|
| 2008 |
Jiang X, Tian F, Du Y, Copeland NG, Jenkins NA, Tessarollo L, Wu X, Pan H, Hu XZ, Xu K, Kenney H, Egan SE, Turley H, Harris AL, Marini AM, et al. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1118-30. PMID 18234890 DOI: 10.1523/Jneurosci.2262-07.2008 |
0.314 |
|
| 2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Turley H, Sivridis E, Bouros D, Bougioukas G, Harris AL, Gatter KC. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway. Cancer Letters. 262: 87-93. PMID 18187257 DOI: 10.1016/j.canlet.2007.11.041 |
0.725 |
|
| 2008 |
Shaida N, Launchbury R, Boddy JL, Jones C, Campo L, Turley H, Kanga S, Banham AH, Malone PR, Harris AL, Fox SB. Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. The Prostate. 68: 336-43. PMID 18163427 DOI: 10.1002/pros.20707 |
0.819 |
|
| 2007 |
Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer. Breast Cancer Research : Bcr. 9: R89. PMID 18096060 DOI: 10.1186/bcr1838 |
0.747 |
|
| 2007 |
Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL. Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Research. 67: 11244-53. PMID 18056450 DOI: 10.1158/0008-5472.CAN-07-0969 |
0.798 |
|
| 2007 |
Kato T, Steers G, Campo L, Roberts H, Leek RD, Turley H, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Harris AL, Gatter KC, Pezzella F. Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. British Journal of Cancer. 97: 1277-86. PMID 17923874 DOI: 10.1038/sj.bjc.6604015 |
0.729 |
|
| 2007 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Chlouverakis G, Vourvouhaki E, Turley H, Harris AL, Gatter KC. Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer. European Journal of Clinical Investigation. 37: 878-86. PMID 17883421 DOI: 10.1111/j.1365-2362.2007.01866.x |
0.608 |
|
| 2007 |
Ord JJ, Agrawal S, Thamboo TP, Roberts I, Campo L, Turley H, Han C, Fawcett DW, Kulkarni RP, Cranston D, Harris AL. An investigation into the prognostic significance of necrosis and hypoxia in high grade and invasive bladder cancer. The Journal of Urology. 178: 677-82. PMID 17574616 DOI: 10.1016/j.juro.2007.03.112 |
0.811 |
|
| 2007 |
Gunningham SP, Currie MJ, Morrin HR, Tan EY, Turley H, Dachs GU, Watson AI, Frampton C, Robinson BA, Fox SB. The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers. The Journal of Pathology. 212: 335-44. PMID 17487938 DOI: 10.1002/path.2174 |
0.551 |
|
| 2007 |
Banham AH, Boddy J, Launchbury R, Han C, Turley H, Malone PR, Harris AL, Fox SB. Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia. The Prostate. 67: 1091-8. PMID 17477366 DOI: 10.1002/pros.20583 |
0.816 |
|
| 2007 |
Winter SC, Buffa FM, Silva P, Miller C, Valentine HR, Turley H, Shah KA, Cox GJ, Corbridge RJ, Homer JJ, Musgrove B, Slevin N, Sloan P, Price P, West CM, et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Research. 67: 3441-9. PMID 17409455 DOI: 10.1158/0008-5472.CAN-06-3322 |
0.671 |
|
| 2007 |
Sington J, Giatromanolaki A, Campo L, Turley H, Pezzella F, Gatter KC. BNIP3 expression in follicular lymphoma. Histopathology. 50: 555-60. PMID 17394490 DOI: 10.1111/j.1365-2559.2007.02657.x |
0.54 |
|
| 2007 |
Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. BNIP3 as a progression marker in primary human breast cancer; opposing functions in in situ versus invasive cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 467-74. PMID 17255267 DOI: 10.1158/1078-0432.CCR-06-1466 |
0.741 |
|
| 2006 |
Nikitenko LL, Cross T, Campo L, Turley H, Leek R, Manek S, Bicknell R, Rees MC. Expression of terminally glycosylated calcitonin receptor-like receptor in uterine leiomyoma: endothelial phenotype and association with microvascular density. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5648-58. PMID 17020966 DOI: 10.1158/1078-0432.CCR-06-0852 |
0.628 |
|
| 2006 |
Giatromanolaki A, Sivridis E, Gatter KC, Turley H, Harris AL, Koukourakis MI. Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis. Gynecologic Oncology. 103: 912-8. PMID 16837029 DOI: 10.1016/j.ygyno.2006.05.043 |
0.651 |
|
| 2006 |
Winter SC, Shah KA, Han C, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. The relation between hypoxia-inducible factor (HIF)=1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer Cancer. 107: 757-766. PMID 16826581 DOI: 10.1002/cncr.21983 |
0.761 |
|
| 2006 |
Bacon AL, Fox S, Turley H, Harris AL. Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. Oncogene. 26: 132-41. PMID 16799636 DOI: 10.1038/sj.onc.1209761 |
0.798 |
|
| 2006 |
Giatromanolaki A, Koukourakis MI, Turley H, Sivridis E, Harris AL, Gatter KC. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 701-7. PMID 16557278 DOI: 10.1038/modpathol.3800579 |
0.679 |
|
| 2006 |
Soilleux EJ, Turley H, Tian YM, Pugh CW, Gatter KC, Harris AL. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 47: 602-10. PMID 16324198 DOI: 10.1111/j.1365-2559.2005.02280.x |
0.466 |
|
| 2005 |
Boddy JL, Fox SB, Han C, Campo L, Turley H, Kanga S, Malone PR, Harris AL. The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer Clinical Cancer Research. 11: 7658-7663. PMID 16278385 DOI: 10.1158/1078-0432.CCR-05-0460 |
0.804 |
|
| 2005 |
Winter SC, Shah KA, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma Clinical Cancer Research. 11: 7614-7620. PMID 16278379 DOI: 10.1158/1078-0432.CCR-05-1097 |
0.777 |
|
| 2005 |
Van den Eynden GG, Van der Auwera I, Van Laere SJ, Colpaert CG, Turley H, Harris AL, van Dam P, Dirix LY, Vermeulen PB, Van Marck EA. Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer. British Journal of Cancer. 93: 1128-36. PMID 16251878 DOI: 10.1038/Sj.Bjc.6602828 |
0.467 |
|
| 2005 |
Zhang Y, Pillai G, Gatter K, Blázquez C, Turley H, Pezzella F, Watt SM. Expression and cellular localization of vascular endothelial growth factor A and its receptors in acute and chronic leukemias: an immunohistochemical study. Human Pathology. 36: 797-805. PMID 16084950 DOI: 10.1016/j.humpath.2005.05.015 |
0.598 |
|
| 2005 |
Daniels RA, Turley H, Kimberley FC, Liu XS, Mongkolsapaya J, Ch'en P, Xu XN, Jin B, Pezzella F, Screaton GR. Expression of TRAIL and TRAIL receptors in normal and malignant tissues Cell Research. 15: 430-438. PMID 15987601 DOI: 10.1038/sj.cr.7290311 |
0.602 |
|
| 2005 |
Couvelard A, O'Toole D, Leek R, Turley H, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas. Histopathology. 46: 668-76. PMID 15910598 DOI: 10.1111/j.1365-2559.2005.02160.x |
0.764 |
|
| 2005 |
Campo L, Turley H, Han C, Pezzella F, Gatter KC, Harris AL, Fox SB. Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival. The Journal of Pathology. 205: 585-91. PMID 15776477 DOI: 10.1002/path.1740 |
0.727 |
|
| 2005 |
Pillai G, Cook N, Turley H, Leek RD, Blasquez C, Pezzella F, Harris AL, Gatter KC. The expression and cellular localization of phosphorylated VEGFR2 in lymphoma and non-neoplastic lymphadenopathy: an immunohistochemical study. Histopathology. 46: 209-16. PMID 15693894 DOI: 10.1111/j.1365-2559.2005.02081.x |
0.757 |
|
| 2005 |
Couvelard A, O'Toole D, Turley H, Leek R, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. British Journal of Cancer. 92: 94-101. PMID 15558070 DOI: 10.1038/sj.bjc.6602245 |
0.791 |
|
| 2004 |
Van der Auwera I, Van Laere SJ, Van den Eynden GG, Benoy I, van Dam P, Colpaert CG, Fox SB, Turley H, Harris AL, Van Marck EA, Vermeulen PB, Dirix LY. Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7965-71. PMID 15585631 DOI: 10.1158/1078-0432.Ccr-04-0063 |
0.546 |
|
| 2004 |
Fox SB, Bragança J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S, Harris AL. CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. Cancer Research. 64: 6075-81. PMID 15342390 DOI: 10.1158/0008-5472.Can-04-0708 |
0.645 |
|
| 2004 |
Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC, Fox SB. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. British Journal of Cancer. 91: 954-8. PMID 15328513 DOI: 10.1038/sj.bjc.6602059 |
0.649 |
|
| 2004 |
Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. The Journal of Biological Chemistry. 279: 42719-25. PMID 15302861 DOI: 10.1074/Jbc.M406713200 |
0.57 |
|
| 2004 |
Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. The Journal of Biological Chemistry. 279: 38458-65. PMID 15247232 DOI: 10.1074/Jbc.M406026200 |
0.71 |
|
| 2004 |
Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. The Journal of Pathology. 203: 808-13. PMID 15221940 DOI: 10.1002/path.1585 |
0.653 |
|
| 2004 |
Fox SB, Turley H, Cheale M, Blázquez C, Roberts H, James N, Cook N, Harris A, Gatter K. Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus. The Journal of Pathology. 202: 313-20. PMID 14991896 DOI: 10.1002/path.1520 |
0.6 |
|
| 2004 |
Stewart M, Turley H, Cook N, Pezzella F, Pillai G, Ogilvie D, Cartlidge S, Paterson D, Copley C, Kendrew J, Barnes C, Harris AL, Gatter KC. The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study. Histopathology. 43: 33-9. PMID 12823710 DOI: 10.1046/j.1365-2559.2003.01644.x |
0.645 |
|
| 2004 |
Ord JJ, Cranston D, Harris AL, Campo L, Turley H, Allen P, Fox S, Davies DR. 773: C-KIT and CK7 Immunohistochemistry in the Differential Diagnosis of Renal Cell Carcinoma, A Study of 111 Cases Journal of Urology. 171: 205-205. DOI: 10.1016/s0022-5347(18)38022-4 |
0.482 |
|
| 2003 |
Braybrooke JP, Levitt NC, Joel S, Davis T, Madhusudan S, Turley H, Wilner S, Harris AL, Talbot DC. Pharmacokinetic study of cisplatin and infusional etoposide phosphate in advanced breast cancer with correlation of response to topoisomerase IIalpha expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4682-8. PMID 14581337 |
0.419 |
|
| 2003 |
Kaklamanis L, Kakolyris S, Turley H, Koukourakis M, Biddolph S, Gatter KC, Harris AL. Neoplastic stroma and epithelium show up-regulation of platelet-derived endothelial cell growth factor/thymidine phosphorylase in colorectal carcinomas but not adenomas. Angiogenesis. 2: 49-55. PMID 14517375 DOI: 10.1023/A:1009002426554 |
0.508 |
|
| 2003 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. The Journal of Pathology. 200: 222-8. PMID 12754744 DOI: 10.1002/path.1330 |
0.731 |
|
| 2003 |
Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 473-82. PMID 12560438 DOI: 10.1200/JCO.2003.11.132 |
0.612 |
|
| 2003 |
Propper DJ, Chao D, Braybrooke JP, Bahl P, Thavasu P, Balkwill F, Turley H, Dobbs N, Gatter K, Talbot DC, Harris AL, Ganesan TS. Low-dose IFN-gamma induces tumor MHC expression in metastatic malignant melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 84-92. PMID 12538455 |
0.402 |
|
| 2002 |
Doussis-Anagnostopoulou IA, Talks KL, Turley H, Debnam P, Tan DC, Mariatos G, Gorgoulis V, Kittas C, Gatter KC. Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease. The Journal of Pathology. 197: 677-83. PMID 12210089 DOI: 10.1002/path.1151 |
0.739 |
|
| 2002 |
Hui EP, Chan AT, Pezzella F, Turley H, To KF, Poon TC, Zee B, Mo F, Teo PM, Huang DP, Gatter KC, Johnson PJ, Harris AL. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2595-604. PMID 12171890 |
0.67 |
|
| 2002 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos C, Turley H, Talks K, Gatter KC, Harris AL. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 53: 1192-202. PMID 12128120 DOI: 10.1016/S0360-3016(02)02848-1 |
0.795 |
|
| 2002 |
Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, Millard P, Fuggle S, Harris AL. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Research. 62: 2493-7. PMID 11980639 |
0.708 |
|
| 2002 |
Stewart M, Talks K, Leek R, Turley H, Pezzella F, Harris A, Gatter K. Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma. Histopathology. 40: 253-60. PMID 11895491 DOI: 10.1046/j.1365-2559.2002.01357.x |
0.82 |
|
| 2002 |
Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Research. 62: 1326-9. PMID 11888900 |
0.832 |
|
| 2001 |
Winters ZE, Hunt NC, Bradburn MJ, Royds JA, Turley H, Harris AL, Norbury CJ. Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis. European Journal of Cancer (Oxford, England : 1990). 37: 2405-12. PMID 11720835 DOI: 10.1016/S0959-8049(01)00327-6 |
0.426 |
|
| 2001 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Talks K, Pezzella F, Gatter KC, Harris AL. Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. British Journal of Cancer. 85: 881-90. PMID 11556841 DOI: 10.1054/bjoc.2001.2018 |
0.825 |
|
| 2000 |
Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. The American Journal of Pathology. 157: 411-21. PMID 10934146 DOI: 10.1016/S0002-9440(10)64554-3 |
0.755 |
|
| 2000 |
Jones A, Fujiyama C, Turner K, Fuggle S, Cranston D, Turley H, Valtola R, Bicknell R, Harris AL. Angiogenesis and lymphangiogenesis in stage 1 germ cell tumours of the testis. Bju International. 86: 80-6. PMID 10886088 DOI: 10.1046/j.1464-410x.2000.00660.x |
0.399 |
|
| 2000 |
Zhang HT, Scott PA, Morbidelli L, Peak S, Moore J, Turley H, Harris AL, Ziche M, Bicknell R. The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. British Journal of Cancer. 83: 63-8. PMID 10883669 DOI: 10.1054/bjoc.2000.1279 |
0.35 |
|
| 2000 |
O'Byrne KJ, Koukourakis MI, Giatromanolaki A, Cox G, Turley H, Steward WP, Gatter K, Harris AL. Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. British Journal of Cancer. 82: 1427-32. PMID 10780522 DOI: 10.1054/bjoc.1999.1129 |
0.553 |
|
| 2000 |
Koukourakis MI, Giatromanolaki A, Guddo F, Kaklamanis L, Vignola M, Kakolyris S, Turley H, Georgoulias V, Bonsignore G, Gatter KC, Harris AL. c-erbB-2 and episialin challenge host immune response by HLA class I expression in human non-small-cell lung cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 104-14. PMID 10687143 DOI: 10.1097/00002371-200001000-00013 |
0.531 |
|
| 1999 |
Turley H, Scott PA, Watts VM, Bicknell R, Harris AL, Gatter KC. Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. The Journal of Pathology. 186: 313-8. PMID 10211122 DOI: 10.1002/(SICI)1096-9896(1998110)186:3<313::AID-PATH188>3.0.CO;2-X |
0.455 |
|
| 1998 |
Zhang L, Scott PA, Turley H, Leek R, Lewis CE, Gatter KC, Harris AL, Mackenzie IZ, Rees MC, Bicknell R. Validation of anti-vascular endothelial growth factor (anti-VEGF) antibodies for immunohistochemical localization of VEGF in tissue sections: expression of VEGF in the human endometrium. The Journal of Pathology. 185: 402-8. PMID 9828839 DOI: 10.1002/(SICI)1096-9896(199808)185:4<402::AID-PATH112>3.0.CO;2-Y |
0.692 |
|
| 1998 |
Wiesener M, Turley H, Allen W, Willam C, Eckardt K, Talks K, Wood S, Gatter K, Harris A, Pugh C, Ratcliffe P, Maxwell P. Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α Blood. 92: 2260-2268. DOI: 10.1182/Blood.V92.7.2260.2260_2260_2268 |
0.74 |
|
| 1997 |
Turley H, Comley M, Houlbrook S, Nozaki N, Kikuchi A, Hickson ID, Gatter K, Harris AL. The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues. British Journal of Cancer. 75: 1340-6. PMID 9155056 DOI: 10.1038/bjc.1997.227 |
0.449 |
|
| 1997 |
Fox SB, Engels K, Comley M, Whitehouse RM, Turley H, Gatter KC, Harris AL. Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 8: 271-5. PMID 9137797 DOI: 10.1023/A:1008280110558 |
0.558 |
|
| 1997 |
Giatromanolaki A, Koukourakis MI, Comley M, Kaklamams L, Turley H, O'Byrne K, Harris AL, Gatter KC. Platelet-derived endothelial cell growth factor (thymidine phosphorylase) expression in lung cancer Journal of Pathology. 181: 196-199. PMID 9120725 DOI: 10.1002/(SICI)1096-9896(199702)181:2<196::AID-PATH763>3.0.CO;2-U |
0.522 |
|
| 1996 |
Sandri M, Hochhauser D, Ayton P, Camplejohn R, Whitehouse R, Turley H, Gatter K, Hickson I, Harris A. Differential expression of the topoisomerase II alpha and beta genes in human breast cancers. British Journal of Cancer. 73: 1518-1524. PMID 8664122 DOI: 10.1038/Bjc.1996.286 |
0.432 |
|
| 1996 |
Fox SB, Westwood M, Moghaddam A, Comley M, Turley H, Whitehouse RM, Bicknell R, Gatter KC, Harris AL. The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium. British Journal of Cancer. 73: 275-80. PMID 8562330 DOI: 10.1038/bjc.1996.49 |
0.649 |
|
| 1995 |
Fox SB, Moghaddam A, Westwood M, Turley H, Bicknell R, Gatter KC, Harris AL. Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: an immunohistochemical study. The Journal of Pathology. 176: 183-90. PMID 7636628 DOI: 10.1002/path.1711760212 |
0.564 |
|
| 1995 |
Moghaddam A, Zhang HT, Fan TP, Hu DE, Lees VC, Turley H, Fox SB, Gatter KC, Harris AL, Bicknell R. Thymidine phosphorylase is angiogenic and promotes tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 92: 998-1002. PMID 7532308 DOI: 10.1073/pnas.92.4.998 |
0.615 |
|
| 1994 |
Pezzella F, Micklem K, Turley H, Pulford K, Jones M, Kocialkowski S, Delia D, Aiello A, Bicknell R, Smith K. Antibody for detecting p53 protein by immunohistochemistry in normal tissues. Journal of Clinical Pathology. 47: 592-6. PMID 8089212 DOI: 10.1136/jcp.47.7.592 |
0.507 |
|
| 1994 |
Dixon J, Kaklamanis L, Turley H, Hickson ID, Leek RD, Harris AL, Gatter KC. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. Journal of Clinical Pathology. 47: 43-7. PMID 7907609 DOI: 10.1136/jcp.47.1.43 |
0.62 |
|
| 1993 |
Pezzella F, Turley H, Kuzu I, Tungekar MF, Dunnill MS, Pierce CB, Harris A, Gatter KC, Mason DY. bcl-2 protein in non-small-cell lung carcinoma. The New England Journal of Medicine. 329: 690-4. PMID 8393963 DOI: 10.1056/NEJM199309023291003 |
0.552 |
|
| 1992 |
Pezzella F, Turley H, Kuzu I, Gatter KC, Mason DY, Harris A. Reversible p53 expression in lung cancer. Lancet (London, England). 340: 922. PMID 1357342 DOI: 10.1016/0140-6736(92)93342-K |
0.536 |
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