Year |
Citation |
Score |
2022 |
Chen WK, Oon CE, Kaur G, Sainson RCA, Li JL. Downregulation of Manic fringe impedes angiogenesis and cell migration of renal carcinoma. Microvascular Research. 104341. PMID 35157839 DOI: 10.1016/j.mvr.2022.104341 |
0.814 |
|
2021 |
Cheng WK, Kaur G, Sjöberg E, Frodin M, Egevad L, Harmenberg U, Li JL, Oon CE. Nuclear and stromal expression of Manic fringe in renal cell carcinoma. Experimental and Molecular Pathology. 104667. PMID 34371013 DOI: 10.1016/j.yexmp.2021.104667 |
0.689 |
|
2020 |
Bridges E, Sheldon H, Kleibeuker E, Ramberger E, Zois C, Barnard A, Harjes U, Li JL, Masiero M, MacLaren R, Harris A. RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain. Angiogenesis. PMID 32506201 DOI: 10.1007/S10456-020-09726-W |
0.794 |
|
2019 |
Masiero M, Li D, Whiteman P, Bentley C, Greig J, Hassanali T, Watts S, Stribbling S, Yates J, Bealing E, Li JL, Chillakuri C, Sheppard D, Serres S, Sarmiento-Soto M, et al. Development of therapeutic anti-JAGGED1 antibodies for cancer therapy. Molecular Cancer Therapeutics. PMID 31395687 DOI: 10.1158/1535-7163.Mct-18-1176 |
0.517 |
|
2017 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. PMID 28445154 DOI: 10.18632/oncotarget.16969 |
0.797 |
|
2016 |
McIntyre A, Hulikova A, Ledaki I, Snell C, Singleton D, Steers G, Seden P, Jones D, Bridges E, Wigfield S, Li JL, Russell A, Swietach P, Harris AL. Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth. Cancer Research. PMID 27197160 DOI: 10.1158/0008-5472.Can-15-1862 |
0.793 |
|
2015 |
Yang J, AlTahan A, Jones DT, Buffa FM, Bridges E, Interiano RB, Qu C, Vogt N, Li JL, Baban D, Ragoussis J, Nicholson R, Davidoff AM, Harris AL. Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598706 DOI: 10.1073/pnas.1422015112 |
0.663 |
|
2015 |
Ledaki I, McIntyre A, Wigfield S, Buffa F, McGowan S, Baban D, Li JL, Harris AL. Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. Oncotarget. 6: 19413-27. PMID 26305601 |
0.8 |
|
2015 |
Leung WY, Roxanis I, Sheldon H, Buffa FM, Li JL, Harris AL, Kong A. Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer. Oncotarget. 6: 5678-94. PMID 25691057 |
0.686 |
|
2014 |
Singleton DC, Rouhi P, Zois CE, Haider S, Li JL, Kessler BM, Cao Y, Harris AL. Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. Oncogene. PMID 25486436 DOI: 10.1038/onc.2014.396 |
0.804 |
|
2014 |
Bensaad K, Favaro E, Lewis CA, Peck B, Lord S, Collins JM, Pinnick KE, Wigfield S, Buffa FM, Li JL, Zhang Q, Wakelam MJ, Karpe F, Schulze A, Harris AL. Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation. Cell Reports. 9: 349-65. PMID 25263561 DOI: 10.1016/j.celrep.2014.08.056 |
0.779 |
|
2014 |
Mohd Nafi SN, Generali D, Kramer-Marek G, Gijsen M, Strina C, Cappelletti M, Andreis D, Haider S, Li JL, Bridges E, Capala J, Ioannis R, Harris AL, Kong A. Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer. Oncotarget. 5: 5934-49. PMID 25153719 |
0.754 |
|
2014 |
Feldinger K, Generali D, Kramer-Marek G, Gijsen M, Ng TB, Wong JH, Strina C, Cappelletti M, Andreis D, Li JL, Bridges E, Turley H, Leek R, Roxanis I, Capala J, et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget. 5: 6633-46. PMID 24952873 |
0.759 |
|
2014 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Li JL, Harris AL. Functional comparison of Notch ligands in tumour angiogenesis Asian Pacific Journal of Tropical Disease. 4: 229. DOI: 10.1016/S2222-1808(14)60523-5 |
0.771 |
|
2013 |
Canonici A, Gijsen M, Mullooly M, Bennett R, Bouguern N, Pedersen K, O'Brien NA, Roxanis I, Li JL, Bridge E, Finn R, Siamon D, McGowan P, Duffy MJ, O'Donovan N, et al. Neratinib overcomes trastuzumab resistance in HER2 amplified breast cancer. Oncotarget. 4: 1592-605. PMID 24009064 DOI: 10.18632/Oncotarget.1148 |
0.619 |
|
2013 |
Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, et al. A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell. 24: 229-41. PMID 23871637 DOI: 10.1016/J.Ccr.2013.06.004 |
0.777 |
|
2013 |
Kumar K, Wigfield S, Gee HE, Devlin CM, Singleton D, Li JL, Buffa F, Huffman M, Sinn AL, Silver J, Turley H, Leek R, Harris AL, Ivan M. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine (Berlin, Germany). 91: 749-58. PMID 23361368 DOI: 10.1007/s00109-013-0996-2 |
0.779 |
|
2013 |
Whiteman P, de Madrid BH, Taylor P, Li D, Heslop R, Viticheep N, Tan JZ, Shimizu H, Callaghan J, Masiero M, Li JL, Banham AH, Harris AL, Lea SM, Redfield C, et al. Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor. The Journal of Biological Chemistry. 288: 7305-12. PMID 23339193 DOI: 10.1074/jbc.M112.428854 |
0.324 |
|
2013 |
Chen Y, Mu X, Wang S, Zhao L, Wu Y, Li J, Li M. WAP four-disulfide core domain protein 2 mediates the proliferation of human ovarian cancer cells through the regulation of growth- and apoptosis-associated genes. Oncology Reports. 29: 288-96. PMID 23129262 DOI: 10.3892/or.2012.2114 |
0.385 |
|
2013 |
Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, Simon AK, Murray JT, Harris AL. Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. The Biochemical Journal. 449: 389-400. PMID 23078367 DOI: 10.1042/Bj20120972 |
0.802 |
|
2012 |
Favaro E, Bensaad K, Chong MG, Tennant DA, Ferguson DJ, Snell C, Steers G, Turley H, Li JL, Günther UL, Buffa FM, McIntyre A, Harris AL. Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells. Cell Metabolism. 16: 751-64. PMID 23177934 DOI: 10.1016/j.cmet.2012.10.017 |
0.802 |
|
2012 |
Jones DT, Lechertier T, Mitter R, Herbert JM, Bicknell R, Jones JL, Li JL, Buffa F, Harris AL, Hodivala-Dilke K. Gene expression analysis in human breast cancer associated blood vessels. Plos One. 7: e44294. PMID 23056178 DOI: 10.1371/journal.pone.0044294 |
0.682 |
|
2012 |
McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877 |
0.789 |
|
2011 |
Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704 |
0.8 |
|
2011 |
Wang S, Huang X, Li Y, Lao H, Zhang Y, Dong H, Xu W, Li JL, Li M. RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathway. Hepatology (Baltimore, Md.). 53: 1932-42. PMID 21391225 DOI: 10.1002/hep.24291 |
0.304 |
|
2010 |
Chen L, Zeng X, Wang J, Briggs SS, O'Neill E, Li J, Leek R, Kerr DJ, Harris AL, Cai S. Roles of tetrahydrobiopterin in promoting tumor angiogenesis. The American Journal of Pathology. 177: 2671-80. PMID 20847284 DOI: 10.2353/ajpath.2010.100025 |
0.721 |
|
2010 |
Biswas S, Troy H, Leek R, Chung YL, Li JL, Raval RR, Turley H, Gatter K, Pezzella F, Griffiths JR, Stubbs M, Harris AL. Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. Journal of Oncology. 2010: 757908. PMID 20652061 DOI: 10.1155/2010/757908 |
0.794 |
|
2010 |
Li JL, Jubb AM, Harris AL. Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity. Future Oncology (London, England). 6: 1099-103. PMID 20624122 DOI: 10.2217/fon.10.62 |
0.722 |
|
2010 |
Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116: 2385-94. PMID 20558614 DOI: 10.1182/blood-2009-08-239228 |
0.796 |
|
2010 |
Favaro E, Ramachandran A, McCormick R, Gee H, Blancher C, Crosby M, Devlin C, Blick C, Buffa F, Li JL, Vojnovic B, Pires das Neves R, Glazer P, Iborra F, Ivan M, et al. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. Plos One. 5: e10345. PMID 20436681 DOI: 10.1371/Journal.Pone.0010345 |
0.749 |
|
2010 |
Jubb AM, Soilleux EJ, Turley H, Steers G, Parker A, Low I, Blades J, Li JL, Allen P, Leek R, Noguera-Troise I, Gatter KC, Thurston G, Harris AL. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. The American Journal of Pathology. 176: 2019-28. PMID 20167860 DOI: 10.2353/ajpath.2010.090908 |
0.798 |
|
2010 |
Pires IM, Bencokova Z, Milani M, Folkes LK, Li JL, Stratford MR, Harris AL, Hammond EM. Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability. Cancer Research. 70: 925-35. PMID 20103649 DOI: 10.1158/0008-5472.CAN-09-2715 |
0.676 |
|
2010 |
Oon C, Li J, Sainson R, Sheldon H, Turley H, Leek R, Harris A. 360 Role of DLL4 and JAG1 in tumour angiogenesis European Journal of Cancer Supplements. 8: 92. DOI: 10.1016/S1359-6349(10)71161-7 |
0.783 |
|
2009 |
Yang J, Ledaki I, Turley H, Gatter KC, Montero JC, Li JL, Harris AL. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Annals of the New York Academy of Sciences. 1177: 185-97. PMID 19845621 DOI: 10.1111/j.1749-6632.2009.05027.x |
0.756 |
|
2009 |
Turley H, Steers G, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Corrigendum. Histopathology. 55: 463-4. PMID 19817897 DOI: 10.1111/j.1365-2559.2009.03412.x |
0.764 |
|
2009 |
Martinez JC, Müller MM, Turley H, Steers G, Choteau L, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues. Histopathology. 54: 598-606. PMID 19413639 DOI: 10.1111/j.1365-2559.2009.03279.x |
0.806 |
|
2009 |
Li JL, Harris AL. Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications. Frontiers in Bioscience (Landmark Edition). 14: 3094-110. PMID 19273260 DOI: 10.2741/3438 |
0.497 |
|
2008 |
Harrington LS, Sainson RC, Williams CK, Taylor JM, Shi W, Li JL, Harris AL. Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells. Microvascular Research. 75: 144-54. PMID 17692341 DOI: 10.1016/j.mvr.2007.06.006 |
0.827 |
|
2007 |
Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL. Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Research. 67: 11244-53. PMID 18056450 DOI: 10.1158/0008-5472.CAN-07-0969 |
0.798 |
|
2007 |
Li JL, Harris AL. The potential of new tumor endothelium-specific markers for the development of antivascular therapy. Cancer Cell. 11: 478-81. PMID 17560330 DOI: 10.1016/j.ccr.2007.05.004 |
0.511 |
|
2007 |
Sainson RCA, Li J, Harrington L, Shi W, Heikamp E, Leek R, Harris AL. In vivo assessment of Delta like‐4 function in tumour development The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a16 |
0.756 |
|
2006 |
Patel NS, Dobbie MS, Rochester M, Steers G, Poulsom R, Le Monnier K, Cranston DW, Li JL, Harris AL. Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer Clinical Cancer Research. 12: 4836-4844. PMID 16914569 DOI: 10.1158/1078-0432.CCR-06-0285 |
0.686 |
|
2006 |
Williams CK, Li JL, Murga M, Harris AL, Tosato G. Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood. 107: 931-9. PMID 16219802 DOI: 10.1182/blood-2005-03-1000 |
0.517 |
|
2006 |
Sainson RC, Harrington L, Shi W, Li JL, Williams C, Harris AL. Delta-Like 4 signaling regulates endothelial and surrounding cells' plasticity and cell fate determination during vascular development Vascular Pharmacology. 45: e43. DOI: 10.1016/j.vph.2006.08.185 |
0.743 |
|
2005 |
Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function Cancer Research. 65: 8690-8697. PMID 16204037 DOI: 10.1158/0008-5472.CAN-05-1208 |
0.775 |
|
2005 |
Li JL, Harris AL. Notch signaling from tumor cells: a new mechanism of angiogenesis. Cancer Cell. 8: 1-3. PMID 16023591 DOI: 10.1016/j.ccr.2005.06.013 |
0.519 |
|
2005 |
Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Molecular and Cellular Biology. 25: 5675-86. PMID 15964822 DOI: 10.1128/Mcb.25.13.5675-5686.2005 |
0.782 |
|
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