Michael Koukourakis - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Giatromanolaki A, Mitrakas A, Anestopoulos I, Kontosis A, Koukourakis IM, Pappa A, Panayiotidis MI, Koukourakis MI. Expression of CD47 and SIRPα Macrophage Immune-Checkpoint Pathway in Non-Small-Cell Lung Cancer. Cancers. 14. PMID 35406573 DOI: 10.3390/cancers14071801  0.301
2022 Koukourakis IM, Giatromanolaki A, Mitrakas A, Koukourakis MI. Loss of HLA-class-I expression in non-small-cell lung cancer: Association with prognosis and anaerobic metabolism. Cellular Immunology. 373: 104495. PMID 35183853 DOI: 10.1016/j.cellimm.2022.104495  0.345
2021 Lamprou I, Tsolou A, Kakouratos C, Mitrakas AG, Xanthopoulou ET, Kassela K, Karakasiliotis I, Zois CE, Giatromanolaki A, Koukourakis MI. Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine. Medical Oncology (Northwood, London, England). 38: 116. PMID 34410522 DOI: 10.1007/s12032-021-01566-y  0.313
2021 Giatromanolaki A, Harris AL, Koukourakis MI. The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer. Cancer & Metabolism. 9: 28. PMID 34344457 DOI: 10.1186/s40170-021-00264-7  0.482
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Koukourakis MI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.549
2021 Tsochantaridis I, Roupas A, Voulgaridou GP, Giatromanolaki A, Koukourakis MI, Panayiotidis MI, Pappa A. Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell Morphology, Proliferation, Migration and Chemosensitivity in Human Colorectal Adenocarcinoma Cells. Biomedicines. 9. PMID 33419031 DOI: 10.3390/biomedicines9010044  0.309
2020 Giatromanolaki A, Harris AL, Banham AH, Contrafouris CA, Koukourakis MI. Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration. British Journal of Cancer. PMID 32066909 DOI: 10.1038/s41416-020-0756-3  0.388
2019 Giatromanolaki A, Koukourakis IM, Balaska K, Mitrakas AG, Harris AL, Koukourakis MI. Programmed death-1 receptor (PD-1) and PD-ligand-1 (PD-L1) expression in non-small cell lung cancer and the immune-suppressive effect of anaerobic glycolysis. Medical Oncology (Northwood, London, England). 36: 76. PMID 31342270 DOI: 10.1007/s12032-019-1299-4  0.389
2019 Giatromanolaki A, Banham AH, Harris AL, Koukourakis MI. FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma. Experimental Lung Research. 1-8. PMID 31134811 DOI: 10.1080/01902148.2019.1617371  0.463
2019 Koukourakis MI, Koukourakis IM, Arelaki S, Kouroupi M, Domoxoudis S, Giatromanolaki A. Angiogenic regeneration defines loco-regional recurrence following pre-operative radio-chemotherapy for rectal cancer: a pilot study. Molecular Biology Reports. 46: 2147-2152. PMID 30721420 DOI: 10.1007/s11033-019-04668-z  0.311
2018 Koukourakis MI, Giatromanolaki A, Fylaktakidou K, Sivridis E, Zois CE, Kalamida D, Mitrakas A, Pouliliou S, Karagounis IV, Simopoulos K, Ferguson DJP, Harris AL. SMER28 is a mTOR-independent small molecule enhancer of autophagy that protects mouse bone morrow and liver against radiotherapy. Investigational New Drugs. PMID 29387992 DOI: 10.1007/s10637-018-0566-0  0.37
2018 Koukourakis MI, Giatromanolaki A, Fylaktakidou K, Kouroupi M, Sivridis E, Zois CE, Kalamida D, Mitrakas A, Pouliliou S, Karagounis IV, Simopoulos K, Ferguson DJP, Harris AL. Amifostine Protects Mouse Liver Against Radiation-induced Autophagy Blockage. Anticancer Research. 38: 227-238. PMID 29277777 DOI: 10.21873/anticanres.12212  0.318
2018 Kouroupi M, Sivridis E, Papazoglou D, Koukourakis MI, Giatromanolaki A. Hypoxia Inducible Factor Expression and Angiogenesis - Analysis in the Pituitary Gland and Patterns of Death. In Vivo (Athens, Greece). 32: 185-190. PMID 29275318 DOI: 10.21873/invivo.11223  0.326
2017 Giatromanolaki A, Balaska K, Kalamida D, Kakouratos C, Sivridis E, Koukourakis MI. Thermogenic protein UCP1 and UCP3 expression in non-small cell lung cancer: relation with glycolysis and anaerobic metabolism. Cancer Biology & Medicine. 14: 396-404. PMID 29372106 DOI: 10.20892/j.issn.2095-3941.2017.0089  0.378
2017 Koukourakis MI, Kalamida D, Mitrakas AG, Liousia M, Pouliliou S, Sivridis E, Giatromanolaki A. Metabolic cooperation between co-cultured lung cancer cells and lung fibroblasts. Laboratory Investigation; a Journal of Technical Methods and Pathology. 97: 1321-1331. PMID 28846077 DOI: 10.1038/labinvest.2017.79  0.311
2017 Giatromanolaki A, Sivridis E, Arelaki S, Koukourakis MI. Expression of enzymes related to glucose metabolism in non-small cell lung cancer and prognosis. Experimental Lung Research. 43: 167-174. PMID 28644754 DOI: 10.1080/01902148.2017.1328714  0.321
2017 Giatromanolaki A, Liousia M, Arelaki S, Kalamida D, Pouliliou S, Mitrakas A, Tsolou A, Sivridis E, Koukourakis M. Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 95: 428-436. PMID 28177758 DOI: 10.1139/bcb-2016-0197  0.337
2016 Koukourakis MI, Giatromanolaki A, Zois CE, Kalamida D, Pouliliou S, Karagounis IV, Yeh TL, Abboud MI, Claridge TD, Schofield CJ, Sivridis E, Simopoulos C, Tokmakidis SP, Harris AL. Normal tissue radioprotection by amifostine via Warburg-type effects. Scientific Reports. 6: 30986. PMID 27507219 DOI: 10.1038/Srep30986  0.419
2016 Voulgaridou GP, Kiziridou M, Mantso T, Chlichlia K, Galanis A, Koukourakis MI, Franco R, Panayiotidis MI, Pappa A. Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells. The International Journal of Biochemistry & Cell Biology. PMID 27276244 DOI: 10.1016/j.biocel.2016.06.004  0.309
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Koukourakis MI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.336
2015 Koukourakis MI, Kalamida D, Giatromanolaki A, Zois CE, Sivridis E, Pouliliou S, Mitrakas A, Gatter KC, Harris AL. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. Plos One. 10: e0137675. PMID 26378792 DOI: 10.1371/journal.pone.0137675  0.432
2015 Giatromanolaki A, Kalamida D, Sivridis E, Karagounis IV, Gatter KC, Harris AL, Koukourakis MI. Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 90: 98-105. PMID 26264650 DOI: 10.1016/j.lungcan.2015.07.008  0.467
2015 Kalamida D, Karagounis IV, Mitrakas A, Kalamida S, Giatromanolaki A, Koukourakis MI. Fever-range hyperthermia vs. hypothermia effect on cancer cell viability, proliferation and HSP90 expression. Plos One. 10: e0116021. PMID 25635828 DOI: 10.1371/journal.pone.0116021  0.315
2014 Giatromanolaki A, Sivridis E, Mitrakas A, Kalamida D, Zois CE, Haider S, Piperidou C, Pappa A, Gatter KC, Harris AL, Koukourakis MI. Autophagy and lysosomal related protein expression patterns in human glioblastoma. Cancer Biology & Therapy. 15: 1468-78. PMID 25482944 DOI: 10.4161/15384047.2014.955719  0.667
2014 Koukourakis MI, Giatromanolaki A, Bottini A, Cappelletti MR, Zanotti L, Allevi G, Strina C, Ardine M, Milani M, Brugnoli G, Martinotti M, Ferrero G, Bertoni R, Ferrozzi F, Harris AL, et al. Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy. British Journal of Cancer. 110: 2209-16. PMID 24722179 DOI: 10.1038/bjc.2014.196  0.77
2013 Giatromanolaki A, Koukourakis MI, Pouliliou S, Gatter KC, Pezzella F, Harris AL, Sivridis E. Overexpression of LC3A autophagy protein in follicular and diffuse large B-cell lymphomas. Hematology/Oncology and Stem Cell Therapy. 6: 20-5. PMID 23664601 DOI: 10.1016/j.hemonc.2013.02.001  0.665
2013 Giatromanolaki A, Koukourakis MI, Koutsopoulos AV, Harris AL, Gatter KC, Sivridis E. Autophagy and hypoxia in colonic adenomas related to aggressive features. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland. 15: e223-30. PMID 23351172 DOI: 10.1111/codi.12147  0.486
2013 Karpathiou G, Sivridis E, Koukourakis M, Mikroulis D, Bouros D, Froudarakis M, Bougioukas G, Maltezos E, Giatromanolaki A. Autophagy and Bcl-2/BNIP3 death regulatory pathway in non-small cell lung carcinomas. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 121: 592-604. PMID 23216071 DOI: 10.1111/apm.12026  0.401
2013 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. High DLL4 expression in tumour-associated vessels predicts for favorable radiotherapy outcome in locally advanced squamous cell head-neck cancer (HNSCC). Angiogenesis. 16: 343-51. PMID 23108591 DOI: 10.1007/s10456-012-9318-5  0.517
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Koukourakis MI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.309
2012 Giatromanolaki A, Koukourakis MI, Sivridis E, Gatter KC, Trarbach T, Folprecht G, Shi MM, Lebwohl D, Jalava T, Laurent D, Meinhardt G, Harris AL. Vascular density analysis in colorectal cancer patients treated with vatalanib (PTK787/ZK222584) in the randomised CONFIRM trials. British Journal of Cancer. 107: 1044-50. PMID 22910317 DOI: 10.1038/bjc.2012.369  0.501
2012 Giatromanolaki A, Koukourakis MI, Koutsopoulos A, Mendrinos S, Sivridis E. The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer. Cancer Biology & Therapy. 13: 1284-9. PMID 22895074 DOI: 10.4161/cbt.21785  0.319
2012 Giatromanolaki A, Sivridis E, Bechrakis NE, Willerding G, St Charitoudis G, Foerster MH, Gatter KC, Harris AL, Koukourakis MI. Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival. Clinical & Experimental Metastasis. 29: 11-7. PMID 21984395 DOI: 10.1007/s10585-011-9424-6  0.558
2011 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Trarbach T, Folprecht G, Shi MM, Lebwohl D, Jalava T, Laurent D, Meinhardt G, Harris AL. Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4892-900. PMID 21632858 DOI: 10.1158/1078-0432.CCR-10-2918  0.513
2011 Sivridis E, Koukourakis MI, Mendrinos SE, Karpouzis A, Fiska A, Kouskoukis C, Giatromanolaki A. Beclin-1 and LC3A expression in cutaneous malignant melanomas: a biphasic survival pattern for beclin-1. Melanoma Research. 21: 188-95. PMID 21537144 DOI: 10.1097/CMR.0b013e328346612c  0.399
2011 Koukourakis MI, Limberis V, Tentes I, Kontomanolis E, Kortsaris A, Sivridis E, Giatromanolaki A. Serum VEGF levels and tissue activation of VEGFR2/KDR receptors in patients with breast and gynecologic cancer. Cytokine. 53: 370-5. PMID 21208810 DOI: 10.1016/j.cyto.2010.12.007  0.319
2010 Giatromanolaki A, Koukourakis MI, Harris AL, Polychronidis A, Gatter KC, Sivridis E. Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas. Journal of Clinical Pathology. 63: 867-72. PMID 20876316 DOI: 10.1136/jcp.2010.079525  0.484
2010 Koukourakis MI, Giatromanolaki A, Sivridis E, Pitiakoudis M, Gatter KC, Harris AL. Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia. British Journal of Cancer. 103: 1209-14. PMID 20842118 DOI: 10.1038/sj.bjc.6605904  0.404
2010 Giatromanolaki A, Bai M, Margaritis D, Bourantas KL, Koukourakis MI, Sivridis E, Gatter KC. Hypoxia and activated VEGF/receptor pathway in multiple myeloma Anticancer Research. 30: 2831-2836. PMID 20683019  0.392
2010 Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL, Gatter KC, Giatromanolaki A. LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. The American Journal of Pathology. 176: 2477-89. PMID 20382705 DOI: 10.2353/ajpath.2010.090049  0.766
2009 Koukourakis MI, Giatromanolaki A, Winter S, Leek R, Sivridis E, Harris AL. Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy. Oncology. 77: 285-92. PMID 19923867 DOI: 10.1159/000259260  0.77
2009 Koukourakis MI, Giatromanolaki A, Sheldon H, Buffa FM, Kouklakis G, Ragoussis I, Sivridis E, Harris AL. Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7069-76. PMID 19887481 DOI: 10.1158/1078-0432.CCR-09-0688  0.469
2009 Giatromanolaki A, Fiska A, Pitsiava D, Kartalis G, Koukourakis MI, Sivridis E. Erythropoietin receptors in endometrial carcinoma as related to HIF1{alpha} and VEGF expression. In Vivo (Athens, Greece). 23: 699-703. PMID 19779103  0.453
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins. Leukemia & Lymphoma. 49: 2181-6. PMID 19021062 DOI: 10.1080/10428190802450629  0.77
2008 Giatromanolaki A, Bates GJ, Koukourakis MI, Sivridis E, Gatter KC, Harris AL, Banham AH. The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer. Gynecologic Oncology. 110: 216-21. PMID 18533240 DOI: 10.1016/j.ygyno.2008.04.021  0.491
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematological Oncology. 26: 219-24. PMID 18461646 DOI: 10.1002/hon.861  0.77
2008 Giatromanolaki A, Koukourakis MI, Pezzella F, Turley H, Sivridis E, Bouros D, Bougioukas G, Harris AL, Gatter KC. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway. Cancer Letters. 262: 87-93. PMID 18187257 DOI: 10.1016/j.canlet.2007.11.041  0.766
2008 Giatromanolaki A, Koukourakis MI, Gatter KC, Harris AL, Sivridis E. BNIP3 expression in endometrial cancer relates to active hypoxia inducible factor 1alpha pathway and prognosis. Journal of Clinical Pathology. 61: 217-20. PMID 17513511 DOI: 10.1136/jcp.2007.046680  0.609
2007 Giatromanolaki A, Koukourakis MI, Sivridis E, Chlouverakis G, Vourvouhaki E, Turley H, Harris AL, Gatter KC. Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer. European Journal of Clinical Investigation. 37: 878-86. PMID 17883421 DOI: 10.1111/j.1365-2362.2007.01866.x  0.695
2007 Koukourakis MI, Giatromanolaki A, Bougioukas G, Sivridis E. Lung cancer: a comparative study of metabolism related protein expression in cancer cells and tumor associated stroma. Cancer Biology & Therapy. 6: 1476-9. PMID 17881895 DOI: 10.4161/cbt.6.9.4635  0.326
2007 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL, Trarbach T, Folprecht G, Shi MM, Meinhardt G. Intratumoral lactate dehydrogenase 5 (LDH5) protein expression is associated with expression of angiogenesis markers and hypoxia in patients with colorectal cancer (CRC) Journal of Clinical Oncology. 25: 4107-4107. DOI: 10.1200/jco.2007.25.18_suppl.4107  0.527
2007 Koukourakis M, Giatromanolaki A, Sivridis E, Gatter K, Harris A, Shi M, Trarbach T, Folprecht G, Meinhardt G. 327 POSTER Expression of intratumoral lactate dehydrogenase 5 (LDH5) and expression of biomarkers for angiogenesis and hypoxia are linked in patients with colorectal cancer (CRC) European Journal of Cancer Supplements. 5: 64-65. DOI: 10.1016/S1359-6349(07)70345-2  0.5
2006 Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas. Journal of Surgical Oncology. 94: 242-7. PMID 16900513 DOI: 10.1002/JSO.20443  0.477
2006 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Lactate dehydrogenase 5 expression in operable colorectal cancer: strong association with survival and activated vascular endothelial growth factor pathway--a report of the Tumour Angiogenesis Research Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4301-8. PMID 16896001 DOI: 10.1200/JCO.2006.05.9501  0.52
2006 Giatromanolaki A, Sivridis E, Koukourakis MI. Angiogenesis in colorectal cancer: prognostic and therapeutic implications. American Journal of Clinical Oncology. 29: 408-17. PMID 16891872 DOI: 10.1097/01.coc.0000221317.56731.4e  0.348
2006 Koukourakis MI, Papazoglou D, Giatromanolaki A, Panagopoulos I, Maltezos E, Harris AL, Gatter KC, Sivridis E. C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1alpha gene define HIF-1alpha protein expression in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 53: 257-62. PMID 16837101 DOI: 10.1016/j.lungcan.2006.05.025  0.454
2006 Giatromanolaki A, Sivridis E, Gatter KC, Turley H, Harris AL, Koukourakis MI. Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis. Gynecologic Oncology. 103: 912-8. PMID 16837029 DOI: 10.1016/j.ygyno.2006.05.043  0.7
2006 Koukourakis MI, Giatromanolaki A, Polychronidis A, Simopoulos C, Gatter KC, Harris AL, Sivridis E. Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer. Cancer Science. 97: 582-8. PMID 16827797 DOI: 10.1111/j.1349-7006.2006.00220.x  0.555
2006 Giatromanolaki A, Koukourakis MI, Turley H, Sivridis E, Harris AL, Gatter KC. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 701-7. PMID 16557278 DOI: 10.1038/modpathol.3800579  0.726
2006 Giatromanolaki A, Sivridis E, Fiska A, Koukourakis MI. Hypoxia-inducible factor-2 alpha (HIF-2 alpha) induces angiogenesis in breast carcinomas. Applied Immunohistochemistry & Molecular Morphology : Aimm. 14: 78-82. PMID 16540735 DOI: 10.1097/01.PAI.0000145182.98577.10  0.356
2006 Koukourakis MI, Giatromanolaki A, Harris AL, Sivridis E. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Research. 66: 632-7. PMID 16423989 DOI: 10.1158/0008-5472.CAN-05-3260  0.463
2006 Koukourakis MI, Bentzen SM, Giatromanolaki A, Wilson GD, Daley FM, Saunders MI, Dische S, Sivridis E, Harris AL. Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial Journal of Clinical Oncology. 24: 727-735. PMID 16418497 DOI: 10.1200/Jco.2005.02.7474  0.503
2006 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Inclusion of vasculature-related variables in the Dukes staging system of colon cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8653-60. PMID 16361550 DOI: 10.1158/1078-0432.CCR-05-1464  0.38
2006 Giatromanolaki A, Koukourakis MI, Sivridis E, Gatter KC, Harris AL, Banham AH. Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1alpha expression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 9-16. PMID 16258506 DOI: 10.1038/modpathol.3800494  0.541
2005 Koukourakis MI, Giatromanolaki A, Simopoulos C, Polychronidis A, Sivridis E. Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer. Clinical & Experimental Metastasis. 22: 25-30. PMID 16132575 DOI: 10.1007/s10585-005-2343-7  0.403
2005 Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma. Neoplasia (New York, N.Y.). 7: 1-6. PMID 15736311 DOI: 10.1593/neo.04373  0.492
2005 Giatromanolaki A, Koukourakis MI, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Sivridis E. c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1alpha dependent. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7972-7. PMID 15585632 DOI: 10.1158/1078-0432.CCR-04-1068  0.464
2005 Giatromanolaki A, Koukourakis MI, Sowter HM, Sivridis E, Gibson S, Gatter KC, Harris AL. BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5566-71. PMID 15328198 DOI: 10.1158/1078-0432.CCR-04-0076  0.804
2004 Koukourakis MI, Giatromanolaki A, Sivridis E, Pastorek J, Karapantzos I, Gatter KC, Harris AL. Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 59: 67-71. PMID 15093900 DOI: 10.1016/j.ijrobp.2003.10.016  0.418
2004 Giatromanolaki A, Koukourakis MI, Kakolyris S, Mavroudis D, Kouroussis C, Mavroudi C, Perraki M, Sivridis E, Georgoulias V. Assessment of highly angiogenic and disseminated in the peripheral blood disease in breast cancer patients predicts for resistance to adjuvant chemotherapy and early relapse. International Journal of Cancer. 108: 620-7. PMID 14696130 DOI: 10.1002/ijc.11593  0.314
2004 Giatromanolaki A, Sivridis E, Kouskoukis C, Gatter KC, Harris AL, Koukourakis MI. Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin. Melanoma Research. 13: 493-501. PMID 14512791 DOI: 10.1097/00008390-200310000-00008  0.55
2003 Koukourakis MI, Giatromanolaki A, Chong W, Simopoulos C, Polychronidis A, Sivridis E, Harris AL. Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha. Cancer Chemotherapy and Pharmacology. 53: 8-14. PMID 14574457 DOI: 10.1007/s00280-003-0691-z  0.43
2003 Koukourakis MI, Giatromanolaki A, Brekken RA, Sivridis E, Gatter KC, Harris AL, Sage EH. Enhanced expression of SPARC/osteonectin in the tumor-associated stroma of non-small cell lung cancer is correlated with markers of hypoxia/acidity and with poor prognosis of patients. Cancer Research. 63: 5376-80. PMID 14500371  0.571
2003 Koukourakis MI, Giatromanolaki A, Sivridis E, Bougioukas G, Didilis V, Gatter KC, Harris AL. Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis. British Journal of Cancer. 89: 877-85. PMID 12942121 DOI: 10.1038/sj.bjc.6601205  0.46
2003 Giatromanolaki A, Sivridis E, Maltezos E, Athanassou N, Papazoglou D, Gatter KC, Harris AL, Koukourakis MI. Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. Arthritis Research & Therapy. 5: R193-201. PMID 12823854 DOI: 10.1186/ar756  0.468
2003 Koukourakis MI, Simopoulos C, Polychronidis A, Perente S, Botaitis S, Giatromanolaki A, Sivridis E. The effect of trastuzumab/docatexel combination on breast cancer angiogenesis: dichotomus effect predictable by the HIFI alpha/VEGF pre-treatment status? Anticancer Research. 23: 1673-80. PMID 12820439  0.378
2003 Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. The Journal of Pathology. 200: 222-8. PMID 12754744 DOI: 10.1002/path.1330  0.776
2003 Koukourakis MI, Giatromanolaki A, Galazios G, Sivridis E. Molecular analysis of local relapse in high-risk breast cancer patients: can radiotherapy fractionation and time factors make a difference? British Journal of Cancer. 88: 711-7. PMID 12618880 DOI: 10.1038/sj.bjc.6600755  0.364
2003 Giatromanolaki A, Sivridis E, Maltezos E, Papazoglou D, Simopoulos C, Gatter KC, Harris AL, Koukourakis MI. Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease. Journal of Clinical Pathology. 56: 209-13. PMID 12610101 DOI: 10.1136/jcp.56.3.209  0.414
2003 Koukourakis MI, Manolas C, Minopoulos G, Giatromanolaki A, Sivridis E. Angiogenesis relates to estrogen receptor negativity, c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast. International Journal of Surgical Pathology. 11: 29-34. PMID 12598915 DOI: 10.1177/106689690301100107  0.322
2003 Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Differential assessment of angiogenic activity and of vascular survival ability (VSA) in breast cancer. Clinical & Experimental Metastasis. 19: 673-9. PMID 12553372 DOI: 10.1023/A:1021354028685  0.476
2003 O'Byrne KJ, Goddard J, Giatromanolaki A, Koukourakis MI. Vascular endothelial growth factor expression in non-small cell lung cancer Methods in Molecular Medicine. 74: 357-373. PMID 12415708 DOI: 10.1385/1-59259-323-2:357  0.366
2003 Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Thymidine phosphorylase expression in gallbladder adenocarcinomas. International Journal of Surgical Pathology. 10: 181-8. PMID 12232571 DOI: 10.1177/106689690201000303  0.529
2002 Sivridis E, Giatromanolaki A, Gatter KC, Harris AL, Koukourakis MI. Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer. 95: 1055-63. PMID 12209691 DOI: 10.1002/cncr.10774  0.454
2002 Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos C, Turley H, Talks K, Gatter KC, Harris AL. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 53: 1192-202. PMID 12128120 DOI: 10.1016/S0360-3016(02)02848-1  0.79
2002 Sivridis E, Giatromanolaki A, Anastasiadis P, Georgiou L, Gatter KC, Harris AL, Bicknell R, Koukourakis MI. Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas. The Journal of Pathology. 196: 416-22. PMID 11920737 DOI: 10.1002/path.1060  0.573
2002 Sivridis E, Giatromanolaki A, Koukourakis MI, Georgiou L, Anastasiadis P. Patterns of episialin/MUC1 expression in endometrial carcinomas and prognostic relevance. Histopathology. 40: 92-100. PMID 11903603 DOI: 10.1046/j.1365-2559.2002.01316.x  0.324
2002 Giatromanolaki A, Sivridis E, Brekken R, Thorpe PE, Anastasiadis P, Gatter KC, Harris AL, Koukourakis MI. The angiogenic "vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications. Cancer. 92: 2569-77. PMID 11745191 DOI: 10.1002/1097-0142(20011115)92:10<2569::AID-CNCR1609>3.0.CO;2-3  0.46
2001 O'Byrne KJ, Cox G, Swinson D, Richardson D, Edwards JG, Lolljee J, Andi A, Koukourakis MI, Giatromanolaki A, Gatter K, Harris AL, Waller D, Jones JL. Towards a biological staging model for operable non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 34: S83-9. PMID 11720747 DOI: 10.1016/S0169-5002(01)00352-X  0.493
2001 Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Talks K, Pezzella F, Gatter KC, Harris AL. Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. British Journal of Cancer. 85: 881-90. PMID 11556841 DOI: 10.1054/bjoc.2001.2018  0.818
2001 Giatromanolaki A, Koukourakis MI, Sivridis E, Thorpe PE, Brekken RA, Konstantinos S, Fountzilas G, Gatter KC, Harris AL. Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas. Clinical & Experimental Metastasis. 18: 313-9. PMID 11448062 DOI: 10.1023/A:1011083121295  0.552
2001 Sivridis E, Giatromanolaki A, Koukourakis M, Anastasiadis P. Endometrial carcinoma: association of steroid hormone receptor expression with low angiogenesis and bcl-2 expression. Virchows Archiv : An International Journal of Pathology. 438: 470-7. PMID 11407475 DOI: 10.1007/s004280000361  0.329
2001 Giatromanolaki A, Stathopoulos GP, Koukourakis MI, Rigatos S, Vrettou E, Kittas C, Fountzilas G, Sivridis E. Angiogenesis and apoptosis-related protein (p53, bcl-2, and bax) expression versus response of gastric adenocarcinomas to paclitaxel and carboplatin chemotherapy. American Journal of Clinical Oncology. 24: 222-6. PMID 11404489 DOI: 10.1097/00000421-200106000-00002  0.359
2001 Giatromanolaki A, Sivridis E, Athanassou N, Zois E, Thorpe PE, Brekken RA, Gatter KC, Harris AL, Koukourakis IM, Koukourakis MI. The angiogenic pathway "vascular endothelial growth factor/flk-1(KDR)-receptor" in rheumatoid arthritis and osteoarthritis. The Journal of Pathology. 194: 101-8. PMID 11329148 DOI: 10.1002/path.842  0.459
2001 Giatromanolaki A, Koukourakis MI, Stathopoulos GP, Kapsoritakis A, Paspatis G, Kakolyris S, Sivridis E, Georgoulias V, Harris AL, Gatter KC. Angiogenic interactions of vascular endothelial growth factor, of thymidine phosphorylase, and of p53 protein expression in locally advanced gastric cancer. Oncology Research. 12: 33-41. PMID 11061344 DOI: 10.3727/000000001108747426  0.436
2001 Giatromanolaki A, Sivridis E, Gatter K, Harris A, Koukourakis M. Patterns of expression of three hypoxia regulated proteins (Hypoxia Inducible Factors HIF1a/HIF1b and Carbonic Anhydrase (CA9) in squamous cell lung carcinoma European Journal of Cancer. 37: S155. DOI: 10.1016/S0959-8049(01)81056-X  0.307
2000 Sivridis E, Giatromanolaki A, Koukourakis MI, Bicknell R, Harris AL, Gatter KC. Thymidine phosphorylase expression in normal and hyperplastic endometrium. Journal of Clinical Pathology. 53: 704-8. PMID 11041061 DOI: 10.1136/jcp.53.9.704  0.379
2000 Giatromanolaki A, Koukourakis MI, Sivridis E, O'Byrne K, Gatter KC, Harris AL. 'Invading edge vs. inner' (edvin) patterns of vascularization: An interplay between angiogenic and vascular survival factors defines the clinical behaviour of non-small cell lung cancer Journal of Pathology. 192: 140-149. PMID 11004689 DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH693>3.0.CO;2-R  0.312
2000 Braybrooke JP, Propper DJ, O'Byrne KJ, Koukourakis MI, Patterson AV, Houlbrook S, Love SD, Varcoe S, Taylor M, Ganesan TS, Talbot DC, Harris AL. Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha British Journal of Cancer. 83: 219-224. PMID 10901374 DOI: 10.1054/bjoc.2000.1230  0.366
2000 O'Byrne KJ, Koukourakis MI, Giatromanolaki A, Cox G, Turley H, Steward WP, Gatter K, Harris AL. Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. British Journal of Cancer. 82: 1427-32. PMID 10780522 DOI: 10.1054/bjoc.1999.1129  0.649
2000 Koukourakis MI, Giatromanolaki A, Guddo F, Kaklamanis L, Vignola M, Kakolyris S, Turley H, Georgoulias V, Bonsignore G, Gatter KC, Harris AL. c-erbB-2 and episialin challenge host immune response by HLA class I expression in human non-small-cell lung cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 104-14. PMID 10687143 DOI: 10.1097/00002371-200001000-00013  0.65
2000 Sivridis E, Giatromanolaki A, Koukourakis MI, Bicknell R, Harris AL, Gatter KC. Thymidine phosphorylase expression in endometrial carcinomas. Clinical & Experimental Metastasis. 17: 445-50. PMID 10651312 DOI: 10.1023/A:1006603709248  0.565
1999 Koukourakis MI, Giatromanolaki A, O'Byrne KJ, Jiles C, Krammer B, Gatter KC, Harris AL. bcl-2 and c-erbB-2 proteins are involved in the regulation of VEGF and of thymidine phosphorylase angiogenic activity in non-small-cell lung cancer Clinical and Experimental Metastasis. 17: 545-554. PMID 10845553 DOI: 10.1023/A:1006780710148  0.567
1999 Giatromanolaki A, Stathopoulos GP, Tsiompanou E, Tsiobanou E, Papadimitriou C, Georgoulias V, Gatter KC, Harris AL, Koukourakis MI. Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer. 86: 1421-30. PMID 10526268 DOI: 10.1002/(SICI)1097-0142(19991015)86:8<1421::AID-CNCR6>3.0.CO;2-X  0.466
1999 Arapandoni-Dadioti P, Giatromanolaki A, Trihia H, Harris AL, Koukourakis MI. Angiogenesis in ductal breast carcinoma. Comparison of microvessel density between primary tumour and lymph node metastasis. Cancer Letters. 137: 145-50. PMID 10374835 DOI: 10.1016/S0304-3835(98)00343-7  0.37
1999 O'Byrne KJ, Dobbs N, Propper DJ, Braybrooke JP, Koukourakis MI, Mitchel K, Woodhull J, Talbot DC, Schally AV, Harris AL. Phase II study of RC-160 (vapreotide), an octapeptide analogue of somatostatin, in the treatment of metastatic breast cancer British Journal of Cancer. 79: 1413-1418. PMID 10188884 DOI: 10.1038/Sj.Bjc.6690226  0.377
1999 Giatromanolaki A, Koukourakis MI, Georgoulias V, Gatter KC, Harris AL, Fountzilas G. Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer. International Journal of Cancer. 80: 810-7. PMID 10074911 DOI: 10.1002/(SICI)1097-0215(19990315)80:6<810::AID-IJC3>3.0.CO;2-J  0.356
1999 Giatromanolaki A, Fountzilas G, Koukourakis MI, Arapandoni P, Theologi V, Kakolyris S, Georgoulias V, Harris AL, Gatter KC. Neo-angiogenesis in locally advanced squamous cell head and neck cancer correlates with thymidine phosphorylase expression and p53 nuclear oncoprotein accumulation. Clinical & Experimental Metastasis. 16: 665-72. PMID 9932613 DOI: 10.1023/A:1006554512338  0.539
1999 Guddo F, Giatromanolaki A, Koukourakis MI, Reina C, Vignola AM, Chlouverakis G, Hilkens J, Gatter KC, Harris AL, Bonsignore G. MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients. Journal of Clinical Pathology. 51: 667-71. PMID 9930070 DOI: 10.1136/jcp.51.9.667  0.486
1999 Giatromanolaki A, Koukourakis M, Fountzilas G, Sivridis E, Gatter K, Harris A. 2027 Up-regulation of angiogenesis and of the angiogenic factor thymidine phosphorylase is involved in cancer regeneration during radiotherapy for head and neck cancer: Implications in the therapeutic outcome International Journal of Radiation Oncology*Biology*Physics. 45: 292. DOI: 10.1016/S0360-3016(99)90297-3  0.444
1998 O'Byrne KJ, Koukourakis MI, Saunders MP, Salisbury AJ, Isaacs R, Varcoe S, Taylor M, Ganesan TS, Harris AL, Talbot DC. Cyclophosphamide, methotrexate and infusional 5-fluorouracil (infusional CMF) in metastatic breast cancer. British Journal of Cancer. 77: 1950-6. PMID 9667673 DOI: 10.1038/bjc.1998.323  0.305
1998 Koukourakis MI, Giatromanolaki A, Kakolyris S, O'Byrne KJ, Apostolikas N, Skarlatos J, Gatter KC, Harris AL. Different patterns of stromal and cancer cell thymidine phosphorylase reactivity in non-small-cell lung cancer: impact on tumour neoangiogenesis and survival. British Journal of Cancer. 77: 1696-703. PMID 9635852 DOI: 10.1038/bjc.1998.280  0.429
1997 Koukourakis MI, Giatromanolaki A, O'Byrne KJ, Whitehouse RM, Talbot DC, Gatter KC, Harris AL. Potential role of bcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer. International Journal of Cancer. 74: 565-70. PMID 9421349 DOI: 10.1002/(SICI)1097-0215(19971219)74:6<565::AID-IJC1>3.0.CO;2-S  0.573
1997 Giatromanolaki A, Koukourakis MI, Comley M, Kaklamams L, Turley H, O'Byrne K, Harris AL, Gatter KC. Platelet-derived endothelial cell growth factor (thymidine phosphorylase) expression in lung cancer Journal of Pathology. 181: 196-199. PMID 9120725 DOI: 10.1002/(SICI)1096-9896(199702)181:2<196::AID-PATH763>3.0.CO;2-U  0.638
1997 Koukourakis MI, Giatromanolaki A, O'Byrne KJ, Comley M, Whitehouse RM, Talbot DC, Gatter KC, Harris AL. Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer. British Journal of Cancer. 75: 477-81. PMID 9052396 DOI: 10.1038/bjc.1997.83  0.398
1997 Giatromanolaki A, Koukourakis M, Koukouraki S, O’Byrne K, Gatter K, Harris A. Focal expression of platelet-derlved endothelial cell growth factor (PD-ECGF)triggers local neo-angiogenesls in non-small cell lung cancer European Journal of Cancer. 33: S44-S45. DOI: 10.1016/S0959-8049(97)84577-7  0.316
1996 Kaklamanis L, Koukourakis MI, Leek R, Giatromanolaki A, Ritter M, Whitehouse R, Gatter KC, Harris AL. Loss of interleukin 4 receptor-associated molecule gp200-MR6 in human breast cancer: prognostic significance. British Journal of Cancer. 74: 1627-31. PMID 8932345 DOI: 10.1038/bjc.1996.599  0.664
1996 Giatromanolaki A, Koukourakis M, O'Byrne K, Fox S, Whitehouse R, Talbot DC, Harris AL, Gatter KC. Prognostic value of angiogenesis in operable non-small cell lung cancer Journal of Pathology. 179: 80-88. PMID 8691350 DOI: 10.1002/(SICI)1096-9896(199605)179:1<80::AID-PATH547>3.0.CO;2-X  0.403
Show low-probability matches.