| Year |
Citation |
Score |
| 2023 |
Canniff NP, Graham JB, Guay KP, Lubicki DA, Eyles SJ, Rauch JN, Hebert DN. TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein. The Journal of Biological Chemistry. 105450. PMID 37949225 DOI: 10.1016/j.jbc.2023.105450 |
0.31 |
|
| 2022 |
Lin Y, Fichou Y, Rauch JN, Zhang X, Kosik KS, Han S. Mapping Phase Diagram of Tau-RNA LLPS Under Live Cell Coculturing Conditions. Methods in Molecular Biology (Clifton, N.J.). 2551: 269-284. PMID 36310209 DOI: 10.1007/978-1-0716-2597-2_18 |
0.438 |
|
| 2022 |
Glasauer SMK, Goderie SK, Rauch JN, Guzman E, Audouard M, Bertucci T, Joy S, Rommelfanger E, Luna G, Keane-Rivera E, Lotz S, Borden S, Armando AM, Quehenberger O, Temple S, et al. Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol. Stem Cell Reports. PMID 35985329 DOI: 10.1016/j.stemcr.2022.07.011 |
0.461 |
|
| 2022 |
Carrettiero DC, Almeida MC, Longhini AP, Rauch JN, Han D, Zhang X, Najafi S, Gestwicki JE, Kosik KS. Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate. Nature Communications. 13: 3074. PMID 35654899 DOI: 10.1038/s41467-022-30751-4 |
0.63 |
|
| 2022 |
Aralis Z, Rauch JN, Audouard M, Valois E, Lach RS, Solley S, Baxter NJ, Kosik KS, Wilson MZ, Acosta-Alvear D, Arias C. CREST, a Cas13-Based, Rugged, Equitable, Scalable Testing (CREST) for SARS-CoV-2 Detection in Patient Samples. Current Protocols. 2: e385. PMID 35195954 DOI: 10.1002/cpz1.385 |
0.405 |
|
| 2021 |
Rauch JN, Valois E, Ponce-Rojas JC, Aralis Z, Lach RS, Zappa F, Audouard M, Solley SC, Vaidya C, Costello M, Smith H, Javanbakht A, Malear B, Polito L, Comer S, et al. Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase-Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students. Jama Network Open. 4: e2037129. PMID 33570576 DOI: 10.1001/jamanetworkopen.2020.37129 |
0.38 |
|
| 2021 |
Makley LN, Johnson OT, Ghanakota P, Rauch JN, Osborn D, Wu TS, Cierpicki T, Carlson HA, Gestwicki JE. Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods. Bioorganic & Medicinal Chemistry. 34: 115990. PMID 33549906 DOI: 10.1016/j.bmc.2020.115990 |
0.545 |
|
| 2021 |
Rauch JN, Valois E, Solley SC, Braig F, Lach RS, Audouard M, Ponce-Rojas JC, Costello MS, Baxter NJ, Kosik KS, Arias C, Acosta-Alvear D, Wilson MZ. A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material. Journal of Clinical Microbiology. PMID 33478979 DOI: 10.1128/JCM.02402-20 |
0.392 |
|
| 2020 |
Zhang X, Vigers M, McCarty J, Rauch JN, Fredrickson GH, Wilson MZ, Shea JE, Han S, Kosik KS. The proline-rich domain promotes Tau liquid-liquid phase separation in cells. The Journal of Cell Biology. 219. PMID 32997736 DOI: 10.1083/jcb.202006054 |
0.492 |
|
| 2020 |
Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS. LRP1 is a master regulator of tau uptake and spread. Nature. 580: 381-385. PMID 32296178 DOI: 10.1038/S41586-020-2156-5 |
0.565 |
|
| 2019 |
Eftekharzadeh B, Banduseela VC, Chiesa G, Martínez-Cristóbal P, Rauch JN, Nath SR, Schwarz DMC, Shao H, Marin-Argany M, Di Sanza C, Giorgetti E, Yu Z, Pierattelli R, Felli IC, Brun-Heath I, et al. Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 4605. PMID 31591399 DOI: 10.1038/S41467-019-12578-8 |
0.528 |
|
| 2019 |
Eftekharzadeh B, Banduseela VC, Chiesa G, Martínez-Cristóbal P, Rauch JN, Nath SR, Schwarz DMC, Shao H, Marin-Argany M, Di Sanza C, Giorgetti E, Yu Z, Pieratelli R, Felli IC, Brun-Heath I, et al. Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 3562. PMID 31395886 DOI: 10.1038/S41467-019-11594-Y |
0.576 |
|
| 2019 |
Lin Y, McCarty J, Rauch JN, Delaney KT, Kosik KS, Fredrickson GH, Shea JE, Han S. Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions. Elife. 8. PMID 30950394 DOI: 10.7554/Elife.42571 |
0.477 |
|
| 2019 |
Hernandez I, Luna G, Rauch JN, Reis SA, Giroux M, Karch CM, Boctor D, Sibih YE, Storm NJ, Diaz A, Kaushik S, Zekanowski C, Kang AA, Hinman CR, Cerovac V, et al. A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy. Science Translational Medicine. 11. PMID 30918111 DOI: 10.1126/Scitranslmed.Aat3005 |
0.526 |
|
| 2018 |
Meister-Broekema M, Freilich R, Jagadeesan C, Rauch JN, Bengoechea R, Motley WW, Kuiper EFE, Minoia M, Furtado GV, van Waarde MAWH, Bird SJ, Rebelo A, Zuchner S, Pytel P, Scherer SS, et al. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks. Nature Communications. 9: 5342. PMID 30559338 DOI: 10.1038/S41467-018-07718-5 |
0.621 |
|
| 2018 |
Fichou Y, Lin Y, Rauch JN, Vigers M, Zeng Z, Srivastava M, Keller TJ, Freed JH, Kosik KS, Han S. Cofactors are essential constituents of stable and seeding-active tau fibrils. Proceedings of the National Academy of Sciences of the United States of America. PMID 30538196 DOI: 10.1073/Pnas.1810058115 |
0.506 |
|
| 2018 |
Mok SA, Condello C, Freilich R, Gillies A, Arhar T, Oroz J, Kadavath H, Julien O, Assimon VA, Rauch JN, Dunyak BM, Lee J, Tsai FTF, Wilson MR, Zweckstetter M, et al. Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nature Structural & Molecular Biology. 25: 384-393. PMID 29728653 DOI: 10.1038/S41594-018-0057-1 |
0.718 |
|
| 2018 |
Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS. Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). Scientific Reports. 8: 6382. PMID 29686391 DOI: 10.1038/S41598-018-24904-Z |
0.538 |
|
| 2018 |
Taylor IR, Dunyak BM, Komiyama T, Shao H, Ran X, Assimon VA, Kalyanaraman C, Rauch JN, Jacobson MP, Zuiderweg ERP, Gestwicki JE. High Throughput Screen for Inhibitors of Protein-Protein Interactions in a Reconstituted Heat Shock Protein 70 (Hsp70) Complex. The Journal of Biological Chemistry. PMID 29414793 DOI: 10.1074/Jbc.Ra117.001575 |
0.62 |
|
| 2017 |
Zhang X, Lin Y, Eschmann NA, Zhou H, Rauch JN, Hernandez I, Guzman E, Kosik KS, Han S. RNA stores tau reversibly in complex coacervates. Plos Biology. 15: e2002183. PMID 28683104 DOI: 10.1371/Journal.Pbio.2002183 |
0.553 |
|
| 2016 |
Rauch JN, Olson SH, Gestwicki JE. Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules. Cold Spring Harbor Perspectives in Medicine. PMID 27940599 DOI: 10.1101/Cshperspect.A024034 |
0.544 |
|
| 2016 |
Rauch JN, Tse E, Freilich R, Mok SA, Makley LN, Southworth DR, Gestwicki JE. BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins. Journal of Molecular Biology. PMID 27884606 DOI: 10.1016/J.Jmb.2016.11.013 |
0.631 |
|
| 2016 |
Young ZT, Rauch JN, Assimon VA, Jinwal UK, Ahn M, Li X, Dunyak BM, Ahmad A, Carlson GA, Srinivasan SR, Zuiderweg ER, Dickey CA, Gestwicki JE. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chemical Biology. PMID 27499529 DOI: 10.1016/J.Chembiol.2016.04.014 |
0.665 |
|
| 2016 |
Rauch JN, Zuiderweg ER, Gestwicki JE. Non-Canonical Interactions Between Heat Shock Cognate Protein 70 (Hsc70) and Bcl2-Associated Anthanogene (BAG) Co-Chaperones Are Important for Client Release. The Journal of Biological Chemistry. PMID 27474739 DOI: 10.1074/Jbc.M116.742502 |
0.567 |
|
| 2016 |
Ouimet CM, Shao H, Rauch JN, Dawod M, Nordhues BA, Dickey CA, Gestwicki JE, Kennedy RT. Protein Cross-linking Capillary Electrophoresis (PXCE) for Protein-Protein Interaction Analysis. Analytical Chemistry. PMID 27434096 DOI: 10.1021/Acs.Analchem.6B02126 |
0.589 |
|
| 2016 |
Morozova K, Clement CC, Kaushik S, Stiller B, Arias E, Ahmad A, Rauch JN, Chatterjee V, Melis C, Scharf B, Gestwicki JE, Cuervo AM, Zuiderweg ER, Santambrogio L. Hsc-70 Structural and Biological Interaction with Phosphatidylserine in Endosomal Microautophagy. The Journal of Biological Chemistry. PMID 27405763 DOI: 10.1074/Jbc.M116.736744 |
0.544 |
|
| 2015 |
Taguwa S, Maringer K, Li X, Bernal-Rubio D, Rauch JN, Gestwicki JE, Andino R, Fernandez-Sesma A, Frydman J. Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection. Cell. PMID 26582131 DOI: 10.1016/J.Cell.2015.10.046 |
0.521 |
|
| 2015 |
Fontaine SN, Rauch JN, Nordhues BA, Assimon VA, Stothert AR, Jinwal UK, Sabbagh JJ, Chang L, Stevens SM, Zuiderweg ER, Gestwicki JE, Dickey CA. Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement. The Journal of Biological Chemistry. 290: 13115-27. PMID 25864199 DOI: 10.1074/Jbc.M115.637595 |
0.643 |
|
| 2015 |
Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Validation of the hsp70-bag3 protein-protein interaction as a potential therapeutic target in cancer. Molecular Cancer Therapeutics. 14: 642-8. PMID 25564440 DOI: 10.1158/1535-7163.Mct-14-0650 |
0.611 |
|
| 2014 |
Rauch JN, Gestwicki JE. Rehabilitating mutant GCase. Chemistry & Biology. 21: 919-20. PMID 25126987 DOI: 10.1016/J.Chembiol.2014.07.010 |
0.446 |
|
| 2014 |
Colvin TA, Gabai VL, Gong J, Calderwood SK, Li H, Gummuluru S, Matchuk ON, Smirnova SG, Orlova NV, Zamulaeva IA, Garcia-Marcos M, Li X, Young ZT, Rauch JN, Gestwicki JE, et al. Hsp70-Bag3 interactions regulate cancer-related signaling networks. Cancer Research. 74: 4731-40. PMID 24994713 DOI: 10.1158/0008-5472.Can-14-0747 |
0.568 |
|
| 2014 |
Rauch JN, Gestwicki JE. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro. The Journal of Biological Chemistry. 289: 1402-14. PMID 24318877 DOI: 10.1074/Jbc.M113.521997 |
0.634 |
|
| 2013 |
Rauch JN, Nie J, Buchholz TJ, Gestwicki JE, Kennedy RT. Development of a capillary electrophoresis platform for identifying inhibitors of protein-protein interactions. Analytical Chemistry. 85: 9824-31. PMID 24060167 DOI: 10.1021/Ac4023082 |
0.565 |
|
| 2013 |
Assimon VA, Gillies AT, Rauch JN, Gestwicki JE. Hsp70 protein complexes as drug targets. Current Pharmaceutical Design. 19: 404-17. PMID 22920901 DOI: 10.2174/138161213804143699 |
0.724 |
|
| 2012 |
Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE. Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70. Chemistry & Biology. 19: 1391-9. PMID 23177194 DOI: 10.1016/J.Chembiol.2012.07.026 |
0.595 |
|
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