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Vinayak Agarwal - Publications

Affiliations: 
Chemistry Georgia Institute of Technology, Atlanta, GA 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nguyen NA, Agarwal V. A Leader-Guided Substrate Tolerant RiPP Brominase Allows Suzuki-Miyaura Cross-Coupling Reactions for Peptides and Proteins. Biochemistry. 62: 1838-1843. PMID 37272553 DOI: 10.1021/acs.biochem.3c00222  0.308
2022 Yi D, Niroula D, Gutekunst WR, Loper JE, Yan Q, Agarwal V. A Nonfunctional Halogenase Masquerades as an Aromatizing Dehydratase in Biosynthesis of Pyrrolic Polyketides by Type I Polyketide Synthases. Acs Chemical Biology. 17: 1351-1356. PMID 35675261 DOI: 10.1021/acschembio.2c00288  0.34
2022 Nguyen NA, Cong Y, Hurrell RC, Arias N, Garg N, Puri AW, Schmidt EW, Agarwal V. A Silent Biosynthetic Gene Cluster from a Methanotrophic Bacterium Potentiates Discovery of a Substrate Promiscuous Proteusin Cyclodehydratase. Acs Chemical Biology. PMID 35666841 DOI: 10.1021/acschembio.2c00251  0.358
2021 Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V. An Obligate Peptidyl Brominase Underlies the Discovery of Highly Distributed Biosynthetic Gene Clusters in Marine Sponge Microbiomes. Journal of the American Chemical Society. PMID 34213321 DOI: 10.1021/jacs.1c03474  0.304
2021 Yi D, Acharya A, Gumbart JC, Gutekunst WR, Agarwal V. Gatekeeping Ketosynthases Dictate Initiation of Assembly Line Biosynthesis of Pyrrolic Polyketides. Journal of the American Chemical Society. PMID 33989500 DOI: 10.1021/jacs.1c02371  0.333
2020 Thapa HR, Lin Z, Yi D, Smith JE, Schmidt EW, Agarwal V. Genetic and biochemical reconstitution of bromoform biosynthesis in Asparagopsis lends insights into seaweed ROS enzymology. Acs Chemical Biology. PMID 32453942 DOI: 10.1021/Acschembio.0C00299  0.303
2019 Thapa HR, Robbins JM, Moore BS, Agarwal V. Insights into thiotemplated pyrrole biosynthesis gained by crystal structure of flavin-dependent oxidase in complex with carrier protein. Biochemistry. PMID 30620182 DOI: 10.1021/acs.biochem.8b01177  0.456
2018 Agarwal V. Assaying Oxidative Coupling Activity of CYP450 Enzymes. Methods in Enzymology. 604: 499-521. PMID 29779665 DOI: 10.1016/bs.mie.2018.01.029  0.362
2018 Thapa HR, Lail AJ, Garg N, Agarwal V. Chemoenzymatic Synthesis of Starting Materials and Characterization of Halogenases Requiring Acyl Carrier Protein-Tethered Substrates. Methods in Enzymology. 604: 333-366. PMID 29779658 DOI: 10.1016/Bs.Mie.2018.01.028  0.398
2017 Estrada P, Manandhar M, Dong SH, Deveryshetty J, Agarwal V, Cronan JE, Nair SK. The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nature Chemical Biology. PMID 28414711 DOI: 10.1038/Nchembio.2359  0.655
2017 Agarwal V, Miles ZD, Winter JM, Eustáquio AS, El Gamal AA, Moore BS. Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse. Chemical Reviews. PMID 28106994 DOI: 10.1021/Acs.Chemrev.6B00571  0.354
2016 Hao Y, Pierce E, Roe D, Morita M, McIntosh JA, Agarwal V, Cheatham TE, Schmidt EW, Nair SK. Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872314 DOI: 10.1073/Pnas.1609869113  0.695
2016 El Gamal AA, Agarwal V, Rahman I, Moore BS. Enzymatic reductive dehalogenation controls the biosynthesis of marine bacterial pyrroles. Journal of the American Chemical Society. PMID 27676265 DOI: 10.1021/Jacs.6B08512  0.328
2016 El Gamal A, Agarwal V, Diethelm S, Rahman I, Schorn MA, Sneed JM, Louie GV, Whalen KE, Mincer TJ, Noel JP, Paul VJ, Moore BS. Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001835 DOI: 10.1073/Pnas.1519695113  0.5
2016 Teufel R, Agarwal V, Moore BS. Unusual flavoenzyme catalysis in marine bacteria. Current Opinion in Chemical Biology. 31: 31-39. PMID 26803009 DOI: 10.1016/J.Cbpa.2016.01.001  0.304
2015 Agarwal V, Diethelm S, Ray L, Garg N, Awakawa T, Dorrestein PC, Moore BS. Chemoenzymatic Synthesis of Acyl Coenzyme A Substrates Enables in Situ Labeling of Small Molecules and Proteins. Organic Letters. 17: 4452-5. PMID 26333306 DOI: 10.1021/Acs.Orglett.5B02113  0.328
2015 Agarwal V, Li J, Rahman I, Borgen M, Aluwihare LI, Biggs JS, Paul VJ, Moore BS. Complexity of naturally produced polybrominated diphenyl ethers revealed via mass spectrometry. Environmental Science & Technology. 49: 1339-46. PMID 25559102 DOI: 10.1021/Es505440J  0.315
2014 Chekan JR, Kwon IH, Agarwal V, Dodd D, Revindran V, Mackie RI, Cann I, Nair SK. Structural and biochemical basis for mannan utilization by Caldanaerobius polysaccharolyticus strain ATCC BAA-17. The Journal of Biological Chemistry. 289: 34965-77. PMID 25342756 DOI: 10.1074/Jbc.M114.579904  0.764
2014 Kazakov T, Kuznedelov K, Semenova E, Mukhamedyarov D, Datsenko KA, Metlitskaya A, Vondenhoff GH, Tikhonov A, Agarwal V, Nair S, Van Aerschot A, Severinov K. The RimL transacetylase provides resistance to translation inhibitor microcin C. Journal of Bacteriology. 196: 3377-85. PMID 25002546 DOI: 10.1128/JB.01584-14  0.55
2014 Agarwal V, Peck SC, Chen JH, Borisova SA, Chekan JR, van der Donk WA, Nair SK. Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation. Chemistry & Biology. 21: 125-35. PMID 24361046 DOI: 10.1016/J.Chembiol.2013.11.006  0.776
2013 Lee J, Hao Y, Blair PM, Melby JO, Agarwal V, Burkhart BJ, Nair SK, Mitchell DA. Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12954-9. PMID 23878226 DOI: 10.1073/Pnas.1306101110  0.727
2013 Perry SL, Guha S, Pawate AS, Bhaskarla A, Agarwal V, Nair SK, Kenis PJ. A microfluidic approach for protein structure determination at room temperature via on-chip anomalous diffraction. Lab On a Chip. 13: 3183-7. PMID 23828485 DOI: 10.1039/C3Lc50276G  0.538
2012 Agarwal V, Pierce E, McIntosh J, Schmidt EW, Nair SK. Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chemistry & Biology. 19: 1411-22. PMID 23177196 DOI: 10.1016/J.Chembiol.2012.09.012  0.603
2012 Agarwal V, Lin S, Lukk T, Nair SK, Cronan JE. Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 17406-11. PMID 23045647 DOI: 10.1073/Pnas.1207028109  0.751
2012 Han Y, Agarwal V, Dodd D, Kim J, Bae B, Mackie RI, Nair SK, Cann IK. Biochemical and structural insights into xylan utilization by the thermophilic bacterium Caldanaerobius polysaccharolyticus. The Journal of Biological Chemistry. 287: 34946-60. PMID 22918832 DOI: 10.1074/Jbc.M112.391532  0.766
2012 Gonzalez-Gutierrez G, Lukk T, Agarwal V, Papke D, Nair SK, Grosman C. Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proceedings of the National Academy of Sciences of the United States of America. 109: 6331-6. PMID 22474383 DOI: 10.1073/Pnas.1119268109  0.705
2012 Agarwal V, Tikhonov A, Metlitskaya A, Severinov K, Nair SK. Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7. Proceedings of the National Academy of Sciences of the United States of America. 109: 4425-30. PMID 22388748 DOI: 10.1073/pnas.1114224109  0.673
2011 Agarwal V, Borisova SA, Metcalf WW, van der Donk WA, Nair SK. Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase. Chemistry & Biology. 18: 1230-40. PMID 22035792 DOI: 10.1016/J.Chembiol.2011.07.019  0.636
2011 Agarwal V, Metlitskaya A, Severinov K, Nair SK. Structural basis for microcin C7 inactivation by the MccE acetyltransferase. The Journal of Biological Chemistry. 286: 21295-303. PMID 21507941 DOI: 10.1074/jbc.M111.226282  0.645
2010 McIntosh JA, Robertson CR, Agarwal V, Nair SK, Bulaj GW, Schmidt EW. Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. Journal of the American Chemical Society. 132: 15499-501. PMID 20961047 DOI: 10.1021/Ja1067806  0.492
2010 Su X, Agarwal V, Dodd D, Bae B, Mackie RI, Nair SK, Cann IK. Mutational insights into the roles of amino acid residues in ligand binding for two closely related family 16 carbohydrate binding modules. The Journal of Biological Chemistry. 285: 34665-76. PMID 20739280 DOI: 10.1074/Jbc.M110.168302  0.746
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