Year |
Citation |
Score |
2022 |
Laskovs M, Partridge L, Slack C. Molecular inhibition of RAS signalling to target ageing and age-related health. Disease Models & Mechanisms. 15. PMID 36111627 DOI: 10.1242/dmm.049627 |
0.547 |
|
2021 |
Chen Z, Cordero J, Alqarni AM, Slack C, Zeidler MP, Bellantuono I. Zoledronate extends healthspan and survival via the mevalonate pathway in a FOXO-dependent manner. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 34137822 DOI: 10.1093/gerona/glab172 |
0.336 |
|
2019 |
Slack C, Tullet J. Signal Transduction Pathways in Ageing. Sub-Cellular Biochemistry. 90: 323-350. PMID 30779014 DOI: 10.1007/978-981-13-2835-0_11 |
0.356 |
|
2016 |
Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell Reports. PMID 27068460 DOI: 10.1016/J.Celrep.2016.03.041 |
0.715 |
|
2015 |
Slack C, Alic N, Partridge L. Could cancer drugs provide ammunition against ageing? Cell Cycle (Georgetown, Tex.). 0. PMID 26587873 DOI: 10.1080/15384101.2015.1118905 |
0.647 |
|
2015 |
Slack C, Alic N, Foley A, Cabecinha M, Hoddinott MP, Partridge L. The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. Cell. 162: 72-83. PMID 26119340 DOI: 10.1016/J.Cell.2015.06.023 |
0.696 |
|
2014 |
Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L. Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports. 6: 608-16. PMID 24508462 DOI: 10.1016/J.Celrep.2014.01.015 |
0.722 |
|
2012 |
Slack C, Foley A, Partridge L. Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila. Plos One. 7: e47699. PMID 23077661 DOI: 10.1371/journal.pone.0047699 |
0.49 |
|
2012 |
Alic N, Hoddinott MP, Foley A, Slack C, Piper MD, Partridge L. Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. Plos One. 7: e45367. PMID 23028964 DOI: 10.1371/Journal.Pone.0045367 |
0.706 |
|
2011 |
Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L. Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Molecular Systems Biology. 7: 502. PMID 21694719 DOI: 10.1038/Msb.2011.36 |
0.718 |
|
2011 |
Slack C, Giannakou ME, Foley A, Goss M, Partridge L. dFOXO-independent effects of reduced insulin-like signaling in Drosophila. Aging Cell. 10: 735-48. PMID 21443682 DOI: 10.1111/j.1474-9726.2011.00707.x |
0.566 |
|
2011 |
Wigby S, Slack C, Grönke S, Martinez P, Calboli FC, Chapman T, Partridge L. Insulin signalling regulates remating in female Drosophila. Proceedings. Biological Sciences / the Royal Society. 278: 424-31. PMID 20739318 DOI: 10.1098/Rspb.2010.1390 |
0.64 |
|
2010 |
Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/Journal.Pgen.1000881 |
0.727 |
|
2010 |
Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L. DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition. Aging Cell. 9: 336-46. PMID 20156206 DOI: 10.1111/J.1474-9726.2010.00558.X |
0.709 |
|
2010 |
Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metabolism. 11: 35-46. PMID 20074526 DOI: 10.1016/J.Cmet.2009.11.010 |
0.725 |
|
2008 |
Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. Plos One. 3: e3721. PMID 19005568 DOI: 10.1371/Journal.Pone.0003721 |
0.722 |
|
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