Alessio Squassina - Publications

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80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pisanu C, Congiu D, Meloni A, Paribello P, Patrinos GP, Severino G, Ardau R, Chillotti C, Manchia M, Squassina A. Dissecting the genetic overlap between severe mental disorders and markers of cellular aging: Identification of pleiotropic genes and druggable targets. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 38402365 DOI: 10.1038/s41386-024-01822-5  0.434
2024 Ou AH, Rosenthal SB, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bauer M, Baune BT, Bellivier F, Benabarre A, ... ... Squassina A, et al. Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study. Translational Psychiatry. 14: 109. PMID 38395906 DOI: 10.1038/s41398-024-02811-4  0.587
2024 Baune BT, Minelli A, Carpiniello B, Contu M, Domínguez Barragán J, Donlo C, Ferensztajn-Rochowiak E, Glaser R, Kelch B, Kobelska P, Kolasa G, Kopeć D, Martínez de Lagrán Cabredo M, Martini P, Mayer MA, ... ... Squassina A, et al. An integrated precision medicine approach in major depressive disorder: a study protocol to create a new algorithm for the prediction of treatment response. Frontiers in Psychiatry. 14: 1279688. PMID 38348362 DOI: 10.3389/fpsyt.2023.1279688  0.355
2023 Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Squassina A, et al. Exploring the genetics of lithium response in bipolar disorders. Research Square. PMID 38077040 DOI: 10.21203/rs.3.rs-3677630/v1  0.587
2023 Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Banzato C, Bauer M, Baune B, ... ... Squassina A, et al. Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study. Research Square. PMID 37886563 DOI: 10.21203/rs.3.rs-3258813/v1  0.587
2023 Carvalho Silva R, Pisanu C, Maffioletti E, Menesello V, Bortolomasi M, Gennarelli M, Baune BT, Squassina A, Minelli A. Biological markers of sex-based differences in major depressive disorder and in antidepressant response. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 76: 89-107. PMID 37595325 DOI: 10.1016/j.euroneuro.2023.07.012  0.317
2023 Herrera-Rivero M, Gutiérrez-Fragoso K, Thalamuthu A, Amare AT, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Abesh B, ... ... Squassina A, et al. Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder. Research Square. PMID 37461719 DOI: 10.21203/rs.3.rs-3068352/v1  0.6
2023 Amare AT, Thalamuthu A, Schubert KO, Fullerton JM, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, ... ... Squassina A, et al. Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Molecular Psychiatry. PMID 37433967 DOI: 10.1038/s41380-023-02149-1  0.628
2023 Pisanu C, Squassina A. RNA Biomarkers in Bipolar Disorder and Response to Mood Stabilizers. International Journal of Molecular Sciences. 24. PMID 37373213 DOI: 10.3390/ijms241210067  0.315
2023 Zai CC, Squassina A, Tiwari AK, Pisanu C, Pinna M, Pinna F, Meloni A, Paribello P, Carpiniello B, Tondo L, Frye MA, Biernacka JM, Coombes BJ, Kennedy JL, Manchia M. A genome-wide association study of antidepressant-induced mania. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110800. PMID 37236419 DOI: 10.1016/j.pnpbp.2023.110800  0.474
2023 Amare A, Thalamuthu A, Schubert KO, Fullerton J, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, ... ... Squassina A, et al. Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder. Research Square. PMID 36824922 DOI: 10.21203/rs.3.rs-2580252/v1  0.653
2022 Manchia M, Isayeva U, Collu R, Primavera D, Deriu L, Caboni E, Iaselli MN, Sundas D, Tusconi M, Pinna F, Paribello P, Scherma M, Pisanu C, Meloni A, Zai CC, ... ... Squassina A, et al. Converging Evidence Points to BDNF as Biomarker of Depressive Symptoms in Schizophrenia-Spectrum Disorders. Brain Sciences. 12. PMID 36552127 DOI: 10.3390/brainsci12121666  0.334
2022 Pisanu C, Squassina A, Paribello P, Dall'Acqua S, Sut S, Nasini S, Bertazzo A, Congiu D, Meloni A, Garzilli M, Guiso B, Suprani F, Pulcinelli V, Iaselli MN, Pinna I, et al. Investigation of Genetic Variants Associated with Tryptophan Metabolite Levels via Serotonin and Kynurenine Pathways in Patients with Bipolar Disorder. Metabolites. 12. PMID 36422266 DOI: 10.3390/metabo12111127  0.312
2022 Squassina A, Meloni A, Congiu D, Bosganas P, Patrinos GP, Lin R, Turecki G, Severino G, Ardau R, Chillotti C, Pisanu C. Analysis on in vitro effect of lithium on telomere length in lymphoblastoid cell lines from bipolar disorder patients with different clinical response to long-term lithium treatment. Human Genomics. 16: 45. PMID 36253798 DOI: 10.1186/s40246-022-00418-8  0.417
2022 Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, ... ... Squassina A, et al. Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 12: 278. PMID 35817769 DOI: 10.1038/s41398-022-02037-2  0.592
2022 Fellendorf FT, Manchia M, Squassina A, Pisanu C, Dall'Acqua S, Sut S, Nasini S, Congiu D, Reininghaus EZ, Garzilli M, Guiso B, Suprani F, Paribello P, Pulcinelli V, Iaselli MN, et al. Is Poor Lithium Response in Individuals with Bipolar Disorder Associated with Increased Degradation of Tryptophan along the Kynurenine Pathway? Results of an Exploratory Study. Journal of Clinical Medicine. 11. PMID 35566641 DOI: 10.3390/jcm11092517  0.458
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry J, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Squassina A, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM. The British Journal of Psychiatry : the Journal of Mental Science. 1. PMID 35505515 DOI: 10.1192/bjp.2022.55  0.543
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Squassina A, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach. The British Journal of Psychiatry : the Journal of Mental Science. 1-10. PMID 35225756 DOI: 10.1192/bjp.2022.28  0.612
2022 Pisanu C, Meloni A, Severino G, Squassina A. Genetic and Epigenetic Markers of Lithium Response. International Journal of Molecular Sciences. 23. PMID 35163479 DOI: 10.3390/ijms23031555  0.509
2022 Kalman JL, Yoshida T, Andlauer TFM, Schulte EC, Adorjan K, Alda M, Ardau R, Aubry JM, Brosch K, Budde M, Chillotti C, Czerski PM, DePaulo RJ, Forstner A, Goes FS, ... ... Squassina A, et al. Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses. European Archives of Psychiatry and Clinical Neuroscience. PMID 35146571 DOI: 10.1007/s00406-021-01366-5  0.504
2022 Pisanu C, Severino G, De Toma I, Dierssen M, Fusar-Poli P, Gennarelli M, Lio P, Maffioletti E, Maron E, Mehta D, Minelli A, Potier MC, Serretti A, Stacey D, van Westrhenen R, ... ... Squassina A, et al. Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 55: 112-157. PMID 35016057 DOI: 10.1016/j.euroneuro.2021.12.005  0.409
2021 Coombes BJ, Millischer V, Batzler A, Larrabee B, Hou L, Papiol S, Heilbronner U, Adli M, Akiyama K, Akula N, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, ... ... Squassina A, et al. Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study. Complex Psychiatry. 7: 80-89. PMID 36408127 DOI: 10.1159/000519707  0.612
2021 Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, ... ... Squassina A, et al. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry : the Journal of Mental Science. 219: 659-669. PMID 35048876 DOI: 10.1192/bjp.2021.102  0.527
2021 Lin R, Lopez JP, Cruceanu C, Pierotti C, Fiori LM, Squassina A, Chillotti C, Dieterich C, Mellios N, Turecki G. Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. Translational Psychiatry. 11: 629. PMID 34893581 DOI: 10.1038/s41398-021-01746-4  0.337
2021 Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, ... ... Squassina A, et al. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 11: 606. PMID 34845190 DOI: 10.1038/s41398-021-01702-2  0.674
2021 Fanelli G, Domschke K, Minelli A, Gennarelli M, Martini P, Bortolomasi M, Maron E, Squassina A, Kasper S, Zohar J, Souery D, Montgomery S, Albani D, Forloni G, Ferentinos P, et al. A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 55: 86-95. PMID 34844152 DOI: 10.1016/j.euroneuro.2021.11.005  0.471
2021 Pisanu C, Vitali E, Meloni A, Congiu D, Severino G, Ardau R, Chillotti C, Trabucchi L, Bortolomasi M, Gennarelli M, Minelli A, Squassina A. Investigating the Role of Leukocyte Telomere Length in Treatment-Resistant Depression and in Response to Electroconvulsive Therapy. Journal of Personalized Medicine. 11. PMID 34834452 DOI: 10.3390/jpm11111100  0.492
2021 Le Clerc S, Lombardi L, Baune BT, Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, ... ... Squassina A, et al. HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders. Scientific Reports. 11: 17823. PMID 34497278 DOI: 10.1038/s41598-021-97140-7  0.571
2021 Pinna M, Manchia M, Pisanu C, Pinna F, Paribello P, Carta A, Meloni A, Conversano C, Del Zompo M, Mola F, Squassina A, Carpiniello B. Protocol for a pharmacogenetic study of antidepressants: characterization of drug-metabolizing profiles of cytochromes CYP2D6 and CYP2C19 in a Sardinian population of patients with major depressive disorder. Psychiatric Genetics. PMID 34282075 DOI: 10.1097/YPG.0000000000000293  0.323
2021 Squassina A. Personalized treatments in neuropsychiatric disorders. Drug Development Research. 82: 618-620. PMID 34196012 DOI: 10.1002/ddr.21854  0.37
2021 Pisanu C, Congiu D, Severino G, Ardau R, Chillotti C, Del Zompo M, Baune BT, Squassina A. Investigation of genetic loci shared between bipolar disorder and risk-taking propensity: potential implications for pharmacological interventions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34035470 DOI: 10.1038/s41386-021-01045-y  0.354
2021 Stone W, Nunes A, Akiyama K, Akula N, Ardau R, Aubry JM, Backlund L, Bauer M, Bellivier F, Cervantes P, Chen HC, Chillotti C, Cruceanu C, Dayer A, Degenhardt F, ... ... Squassina A, et al. Prediction of lithium response using genomic data. Scientific Reports. 11: 1155. PMID 33441847 DOI: 10.1038/s41598-020-80814-z  0.507
2021 Nunes A, Stone W, Ardau R, Berghöfer A, Bocchetta A, Chillotti C, Deiana V, Degenhardt F, Forstner AJ, Garnham JS, Grof E, Hajek T, Manchia M, Mattheisen M, McMahon F, ... ... Squassina A, et al. Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder. Translational Psychiatry. 11: 36. PMID 33431852 DOI: 10.1038/s41398-020-01148-y  0.569
2020 Squassina A, Manchia M, Pisanu C, Ardau R, Arzedi C, Bocchetta A, Caria P, Cocco C, Congiu D, Cossu E, Dettori T, Frau DV, Garzilli M, Manca E, Meloni A, et al. Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32919410 DOI: 10.1038/S41386-020-00844-Z  0.426
2020 Fontana A, Manchia M, Panebianco C, Paribello P, Arzedi C, Cossu E, Garzilli M, Montis MA, Mura A, Pisanu C, Congiu D, Copetti M, Pinna F, Carpiniello B, Squassina A, et al. Exploring the Role of Gut Microbiota in Major Depressive Disorder and in Treatment Resistance to Antidepressants. Biomedicines. 8. PMID 32867257 DOI: 10.3390/Biomedicines8090311  0.329
2020 Manchia M, Pisanu C, Squassina A, Carpiniello B. Challenges and Future Prospects of Precision Medicine in Psychiatry. Pharmacogenomics and Personalized Medicine. 13: 127-140. PMID 32425581 DOI: 10.2147/Pgpm.S198225  0.325
2020 Pisanu C, Congiu D, Manchia M, Caria P, Cocco C, Dettori T, Frau DV, Manca E, Meloni A, Nieddu M, Noli B, Pinna F, Robledo R, Sogos V, Ferri GL, ... ... Squassina A, et al. Differences in telomere length between patients with bipolar disorder and controls are influenced by lithium treatment. Pharmacogenomics. PMID 32372689 DOI: 10.2217/Pgs-2020-0028  0.454
2020 Squassina A, Niola P, Lopez JP, Cruceanu C, Pisanu C, Congiu D, Severino G, Ardau R, Chillotti C, Alda M, Turecki G, Del Zompo M. MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 32241689 DOI: 10.1016/J.Euroneuro.2020.03.005  0.435
2020 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Squassina A, et al. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry. PMID 32203155 DOI: 10.1038/S41380-020-0689-5  0.643
2020 Steardo L, Manchia M, Carpiniello B, Pisanu C, Steardo L, Squassina A. Clinical, genetic, and brain imaging predictors of risk for bipolar disorder in high-risk individuals. Expert Review of Molecular Diagnostics. 1-7. PMID 32054361 DOI: 10.1080/14737159.2020.1727743  0.337
2020 Manchia M, Paribello P, Arzedi C, Bocchetta A, Caria P, Cocco C, Congiu D, Cossu E, Dettori T, Frau DV, Garzilli M, Manca E, Meloni A, Montis MA, Mura A, ... ... Squassina A, et al. A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders. Bmj Open. 10: e032513. PMID 31988227 DOI: 10.1136/Bmjopen-2019-032513  0.322
2020 Squassina A, Meloni A, Chillotti C, Pisanu C. Zinc finger proteins in psychiatric disorders and response to psychotropic medications. Psychiatric Genetics. 29: 132-141. PMID 31464994 DOI: 10.1097/YPG.0000000000000231  0.375
2019 Manchia M, Squassina A, Pisanu C, Congiu D, Garzilli M, Guiso B, Suprani F, Paribello P, Pulcinelli V, Iaselli MN, Pinna F, Valtorta F, Carpiniello B, Comai S. Investigating the relationship between melatonin levels, melatonin system, microbiota composition and bipolar disorder psychopathology across the different phases of the disease. International Journal of Bipolar Disorders. 7: 27. PMID 31814040 DOI: 10.1186/S40345-019-0163-Y  0.363
2019 Pisanu C, Tsermpini EE, Skokou M, Kordou Z, Gourzis P, Assimakopoulos K, Congiu D, Meloni A, Balasopoulos D, Patrinos GP, Squassina A. Leukocyte telomere length is reduced in patients with major depressive disorder. Drug Development Research. 81: 268-273. PMID 31675136 DOI: 10.1002/ddr.21612  0.412
2019 Pisanu C, Lundin E, Preisig M, Gholam-Rezaee M, Castelao E, Pistis G, Merikangas KR, Glaus J, Squassina A, Del Zompo M, Schiöth HB, Mwinyi J. Major depression subtypes are differentially associated with migraine subtype, prevalence and severity. Cephalalgia : An International Journal of Headache. 333102419884935. PMID 31645113 DOI: 10.1177/0333102419884935  0.314
2019 Pisanu C, Squassina A. Treatment-Resistant Schizophrenia: Insights From Genetic Studies and Machine Learning Approaches. Frontiers in Pharmacology. 10: 617. PMID 31191325 DOI: 10.3389/fphar.2019.00617  0.371
2019 Squassina A, Pisanu C, Vanni R. Mood Disorders, Accelerated Aging, and Inflammation: Is the Link Hidden in Telomeres? Cells. 8. PMID 30650526 DOI: 10.3390/cells8010052  0.375
2019 Squassina A, Pisanu C. Personalized medicine in bipolar disorder: how can we overcome the barriers to clinical translation? Personalized Medicine. 10: 765-768. PMID 29776275 DOI: 10.2217/pme.13.86  0.352
2018 Pisanu C, Congiu D, Costa M, Chillotti C, Ardau R, Severino G, Angius A, Heilbronner U, Hou L, McMahon FJ, Schulze TG, Del Zompo M, Squassina A. Convergent analysis of genome-wide genotyping and transcriptomic data suggests association of zinc finger genes with lithium response in bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30318722 DOI: 10.1002/ajmg.b.32663  0.44
2018 Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, ... ... Squassina A, et al. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study. Bipolar Disorders. PMID 29956436 DOI: 10.1111/Bdi.12659  0.574
2018 Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, ... ... Squassina A, et al. Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder. Frontiers in Psychiatry. 9: 207. PMID 29904359 DOI: 10.3389/Fpsyt.2018.00207  0.502
2018 Pisanu C, Heilbronner U, Squassina A. The Role of Pharmacogenomics in Bipolar Disorder: Moving Towards Precision Medicine. Molecular Diagnosis & Therapy. PMID 29790107 DOI: 10.1007/s40291-018-0335-y  0.466
2017 Pisanu C, Katsila T, Patrinos GP, Squassina A. Recent trends on the role of epigenomics, metabolomics and noncoding RNAs in rationalizing mood stabilizing treatment. Pharmacogenomics. 19: 129-143. PMID 29199496 DOI: 10.2217/pgs-2017-0111  0.352
2017 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Squassina A, et al. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. Jama Psychiatry. PMID 29121268 DOI: 10.1001/Jamapsychiatry.2017.3433  0.634
2017 Milanesi E, Voinsky I, Hadar A, Srouji A, Maj C, Shekhtman T, Gershovits M, Gilad S, Chillotti C, Squassina A, Potash JB, Schulze TG, Goes F, Zandi P, Kelsoe JR, et al. RNA-sequencing of bipolar disorder lymphoblastoid cell lines implicates the neurotrophic factor HRP-3 in lithium's clinical efficacy. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-26. PMID 28854847 DOI: 10.1080/15622975.2017.1372629  0.454
2017 Papadima EM, Niola P, Melis C, Pisanu C, Congiu D, Cruceanu C, Lopez JP, Turecki G, Ardau R, Severino G, Chillotti C, Del Zompo M, Squassina A. Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients. Journal of Molecular Neuroscience : Mn. PMID 28616776 DOI: 10.1007/S12031-017-0938-5  0.372
2016 Tsermpini EE, Zhang Y, Niola P, Chillotti C, Ardau R, Bocchetta A, Patrinos GP, Zompo MD, Severino G, Lee MT, Squassina A. Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study. Neuroscience Letters. PMID 27923663 DOI: 10.1016/j.neulet.2016.12.001  0.403
2016 Pisanu C, Melis C, Squassina A. Lithium Pharmacogenetics: Where Do We Stand? Drug Development Research. 77: 368-373. PMID 27633500 DOI: 10.1002/ddr.21341  0.467
2016 Pisanu C, Papadima EM, Del Zompo M, Squassina A. Understanding the molecular mechanisms underlying mood stabilizer treatments in bipolar disorder: potential involvement of epigenetics. Neuroscience Letters. PMID 27343410 DOI: 10.1016/j.neulet.2016.06.045  0.424
2016 Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, ... ... Squassina A, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Human Molecular Genetics. PMID 27329760 DOI: 10.1093/Hmg/Ddw181  0.566
2016 Squassina A, Pisanu C, Congiu D, Caria P, Frau D, Niola P, Melis C, Baggiani G, Lopez JP, Cruceanu C, Turecki G, Severino G, Bocchetta A, Vanni R, Chillotti C, et al. Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27084304 DOI: 10.1016/J.Euroneuro.2016.03.020  0.373
2016 Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Squassina A, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet (London, England). PMID 26806518 DOI: 10.1016/S0140-6736(16)00143-4  0.643
2015 Squassina A, Pisanu C, Corbett N, Alda M. Telomere length in bipolar disorder and lithium response. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26621262 DOI: 10.1016/J.Euroneuro.2015.10.008  0.545
2015 Viswanath B, Jose SP, Squassina A, Thirthalli J, Purushottam M, Mukherjee O, Vladimirov V, Patrinos GP, Del Zompo M, Jain S. Cellular models to study bipolar disorder: A systematic review. Journal of Affective Disorders. 184: 36-50. PMID 26070045 DOI: 10.1016/J.Jad.2015.05.037  0.355
2015 Costa M, Squassina A, Piras IS, Pisanu C, Congiu D, Niola P, Angius A, Chillotti C, Ardau R, Severino G, Stochino E, Deidda A, Persico AM, Alda M, Del Zompo M. Preliminary Transcriptome Analysis in Lymphoblasts from Cluster Headache and Bipolar Disorder Patients Implicates Dysregulation of Circadian and Serotonergic Genes. Journal of Molecular Neuroscience : Mn. 56: 688-95. PMID 25912293 DOI: 10.1007/S12031-015-0567-9  0.513
2015 Milanesi E, Hadar A, Maffioletti E, Werner H, Shomron N, Gennarelli M, Schulze TG, Costa M, Del Zompo M, Squassina A, Gurwitz D. Insulin-like Growth Factor 1 Differentially Affects Lithium Sensitivity of Lymphoblastoid Cell Lines from Lithium Responder and Non-responder Bipolar Disorder Patients. Journal of Molecular Neuroscience : Mn. 56: 681-7. PMID 25740013 DOI: 10.1007/s12031-015-0523-8  0.36
2014 Niola P, Gross JA, Lopez JP, Chillotti C, Deiana V, Manchia M, Georgitsi M, Patrinos GP, Alda M, Turecki G, Del Zompo M, Squassina A. Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene. Psychiatry Research. 220: 1167-8. PMID 25288042 DOI: 10.1016/J.Psychres.2014.09.014  0.399
2014 Floris G, Di Stefano F, Pisanu C, Chillotti C, Murru MR, Congiu D, Cuccu S, Ruiu E, Borghero G, Cannas A, Marrosu MG, Marrosu F, Del Zompo M, Squassina A. C9ORF72 repeat expansion and bipolar disorder - is there a link? No mutation detected in a Sardinian cohort of patients with bipolar disorder. Bipolar Disorders. 16: 667-8. PMID 24798095 DOI: 10.1111/bdi.12210  0.375
2014 Tsermpini EE, Assimakopoulos K, Bartsakoulia M, Iconomou G, Papadima EM, Mitropoulos K, Squassina A, Patrinos GP. Individualizing clozapine and risperidone treatment for schizophrenia patients. Pharmacogenomics. 15: 95-110. PMID 24329194 DOI: 10.2217/pgs.13.219  0.326
2013 Pisanu C, Congiu D, Costa M, Sestu M, Chillotti C, Ardau R, Deiana V, Manchia M, Squassina A, Del Zompo M. No association of endocannabinoid genes with bipolar disorder or lithium response in a Sardinian sample. Psychiatry Research. 210: 887-90. PMID 24126189 DOI: 10.1016/J.Psychres.2013.09.025  0.415
2013 Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng AT, ... ... Squassina A, et al. Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. Plos One. 8: e65636. PMID 23840348 DOI: 10.1371/Journal.Pone.0065636  0.584
2013 Squassina A, Manchia M, Chillotti C, Deiana V, Congiu D, Paribello F, Roncada P, Soggiu A, Piras C, Urbani A, Robertson GS, Keddy P, Turecki G, Rouleau GA, Alda M, et al. Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2209-18. PMID 23768751 DOI: 10.1017/S1461145713000655  0.501
2013 Squassina A, Costa M, Congiu D, Manchia M, Angius A, Deiana V, Ardau R, Chillotti C, Severino G, Calza S, Del Zompo M. Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 73: 1-7. PMID 23619527 DOI: 10.1016/J.Phrs.2013.04.004  0.356
2013 Severino G, Squassina A, Costa M, Pisanu C, Calza S, Alda M, Del Zompo M, Manchia M. Pharmacogenomics of bipolar disorder. Pharmacogenomics. 14: 655-74. PMID 23570469 DOI: 10.2217/Pgs.13.51  0.613
2011 Squassina A, Manchia M, Borg J, Congiu D, Costa M, Georgitsi M, Chillotti C, Ardau R, Mitropoulos K, Severino G, Del Zompo M, Patrinos GP. Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder. Pharmacogenomics. 12: 1559-69. PMID 21961650 DOI: 10.2217/Pgs.11.102  0.511
2010 Squassina A, Manchia M, Del Zompo M. Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder. Human Genomics and Proteomics : Hgp. 2010: 159761. PMID 20981231 DOI: 10.4061/2010/159761  0.454
2010 Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O, Hashimoto R, Hauser J, ... ... Squassina A, et al. The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment. Neuropsychobiology. 62: 72-8. PMID 20453537 DOI: 10.1159/000314708  0.646
2010 Manchia M, Zai CC, Squassina A, Vincent JB, De Luca V, Kennedy JL. Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 20: 663-70. PMID 20452754 DOI: 10.1016/J.Euroneuro.2010.04.001  0.37
2009 Manchia M, Congiu D, Squassina A, Lampus S, Ardau R, Chillotti C, Severino G, Del Zompo M. No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample. Psychiatry Research. 169: 164-6. PMID 19647327 DOI: 10.1016/J.Psychres.2008.12.004  0.347
2008 Squassina A, Congiu D, Manconi F, Manchia M, Chillotti C, Lampus S, Severino G, Zompo MD. The PDLIM5 gene and lithium prophylaxis: an association and gene expression analysis in Sardinian patients with bipolar disorder. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 57: 369-73. PMID 18456508 DOI: 10.1016/J.Phrs.2008.03.011  0.363
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