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Syn Kok Yeo - Publications

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Autophagy, Breast Cancer, Intratumoral Heterogeneity
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hao M, Lu P, Sotropa S, Manupati K, Yeo SK, Guan JL. In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux. Cell Reports. 43: 113780. PMID 38363674 DOI: 10.1016/j.celrep.2024.113780  0.616
2023 Yeo SK, Haas M, Manupati K, Hao M, Yang F, Chen S, Guan JL. AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer. Autophagy. 1-16. PMID 37733921 DOI: 10.1080/15548627.2023.2259775  0.576
2022 Yi F, Cai C, Ruan B, Hao M, Yeo SK, Haas M, Yang F, Zhang X, Guan JL. Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region. Autophagy. 1-16. PMID 36394358 DOI: 10.1080/15548627.2022.2148432  0.489
2022 Holm TM, Yeo S, Turner KM, Guan JL. Targeting Autophagy in Thyroid Cancer: EMT, Apoptosis, and Cancer Stem Cells. Frontiers in Cell and Developmental Biology. 10: 821855. PMID 35846375 DOI: 10.3389/fcell.2022.821855  0.611
2022 Manupati K, Paul R, Hao M, Haas M, Bian ZC, Holm TM, Guan JL, Yeo SK. Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells. Cancers. 14. PMID 35053617 DOI: 10.3390/cancers14020455  0.562
2021 Liu H, Wang C, Yi F, Yeo S, Haas M, Tang X, Guan JL. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific Reports. 11: 23907. PMID 34903812 DOI: 10.1038/s41598-021-03404-7  0.499
2021 Turner KM, Yeo SK, Holm TM, Shaughnessy E, Guan JL. Heterogeneity Within Molecular Subtypes of Breast Cancer. American Journal of Physiology. Cell Physiology. PMID 34191627 DOI: 10.1152/ajpcell.00109.2021  0.591
2021 Wang C, Haas M, Yeo SK, Sebti S, Fernández ÁF, Zou Z, Levine B, Guan JL. Enhanced autophagy in knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy. 1-14. PMID 34101533 DOI: 10.1080/15548627.2021.1936358  0.475
2021 Hao M, Yeo SK, Guan JL. Autophagy inhibition perturbs ERBB2 trafficking and abolishes tumorigenesis in ERBB2-driven breast cancer. Autophagy. 1-2. PMID 33757386 DOI: 10.1080/15548627.2021.1907168  0.593
2021 Wang C, Haas MA, Yeo SK, Paul R, Yang F, Vallabhapurapu S, Qi X, Plas DR, Guan JL. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British Journal of Cancer. PMID 33723393 DOI: 10.1038/s41416-021-01294-0  0.565
2021 Yang Y, Leonard M, Luo Z, Yeo S, Bick G, Hao M, Cai C, Charif M, Wang J, Guan JL, Lower EE, Zhang X. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Reports. 34: 108822. PMID 33691110 DOI: 10.1016/j.celrep.2021.108822  0.613
2021 Hao M, Yeo SK, Turner K, Harold A, Yang Y, Zhang X, Guan JL. Autophagy blockade limits HER2+ breast cancer tumorigenesis by perturbing HER2 trafficking and promoting release via small extracellular vesicles. Developmental Cell. PMID 33472043 DOI: 10.1016/j.devcel.2020.12.016  0.635
2020 Yeo SK, Zhu X, Okamoto T, Hao M, Wang C, Lu P, Lu LJ, Guan JL. Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer. Elife. 9. PMID 32840210 DOI: 10.7554/Elife.58810  0.599
2020 Yeo SK, Guan JL. Regulation of immune checkpoint blockade efficacy in breast cancer by FIP200: A canonical-autophagy-independent function. Cell Stress. 4: 216-217. PMID 32743346 DOI: 10.15698/cst2020.08.229  0.624
2020 Yeo SK, Wang C, Guan JL. Role of FIP200 in inflammatory processes beyond its canonical autophagy function. Biochemical Society Transactions. PMID 32662824 DOI: 10.1042/Bst20191156  0.523
2020 Paul R, Luo M, Mo X, Lu J, Yeo SK, Guan JL. Correction to: FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors. Breast Cancer Research : Bcr. 22: 71. PMID 32600368 DOI: 10.1186/S13058-020-01310-W  0.474
2020 Okamoto T, Yeo SK, Hao M, Copley MR, Haas MA, Chen S, Guan JL. FIP200 suppresses immune checkpoint therapy responses in breast cancers by limiting AZI2/TBK1/IRF signaling independent of its canonical autophagy function. Cancer Research. PMID 32580962 DOI: 10.1158/0008-5472.Can-20-0519  0.625
2020 Paul R, Luo M, Mo X, Lu J, Yeo SK, Guan JL. FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors. Breast Cancer Research : Bcr. 22: 59. PMID 32493400 DOI: 10.1186/S13058-020-01298-3  0.585
2020 Yang F, Sun S, Wang C, Haas M, Yeo S, Guan JL. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. British Journal of Cancer. PMID 32336756 DOI: 10.1038/S41416-020-0839-1  0.501
2020 Wu HJ, Hao M, Yeo SK, Guan JL. FAK signaling in cancer-associated fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication. Oncogene. PMID 31988451 DOI: 10.1038/S41388-020-1162-2  0.611
2019 Wang C, Haas MA, Yang F, Yeo S, Okamoto T, Chen S, Wen J, Sarma P, Plas DR, Guan JL. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells. Nature Metabolism. 1: 1127-1140. PMID 32577608 DOI: 10.1038/s42255-019-0137-5  0.528
2018 Yeo SK, Paul R, Haas M, Wang C, Guan JL. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy. PMID 29938573 DOI: 10.1080/15548627.2018.1460010  0.608
2017 Yeo SK, Guan JL. Breast Cancer: Multiple Subtypes within a Tumor? Trends in Cancer. 3: 753-760. PMID 29120751 DOI: 10.1016/J.Trecan.2017.09.001  0.602
2017 Wang C, Yeo S, Haas MA, Guan JL. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. The Journal of Cell Biology. PMID 28634261 DOI: 10.1083/Jcb.201609093  0.541
2017 Yeo SK, French R, Spada F, Clarkson R. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment. PMID 28190248 DOI: 10.1007/s10549-017-4149-0  0.436
2016 Yeo SK, Guan JL. Hierarchical heterogeneity in mammary tumors and its regulation by autophagy. Autophagy. 1-2. PMID 27624535 DOI: 10.1080/15548627.2016.1213928  0.591
2016 Yeo SK, Wen J, Chen S, Guan JL. Autophagy differentially regulates distinct breast cancer stem-like cells in murine models via EGFR/Stat3 and Tgfß/Smad signaling. Cancer Research. PMID 27197172 DOI: 10.1158/0008-5472.Can-15-2946  0.643
2016 Chen S, Wang C, Yeo S, Liang CC, Okamoto T, Sun S, Wen J, Guan JL. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes & Development. PMID 27013233 DOI: 10.1101/gad.276428.115  0.504
2016 Wang C, Chen S, Yeo S, Karsli-Uzunbas G, White E, Mizushima N, Virgin HW, Guan JL. Correction: Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of Cell Biology. PMID 27002165 DOI: 10.1083/jcb.20150702303082016c  0.475
2016 Wang C, Chen S, Yeo S, Karsli-Uzunbas G, White E, Mizushima N, Virgin HW, Guan JL. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of Cell Biology. 212: 545-60. PMID 26929451 DOI: 10.1083/Jcb.201507023  0.54
2015 Wen J, Yeo S, Wang C, Chen S, Sun S, Haas MA, Tu W, Jin F, Guan JL. Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis. Breast Cancer Research and Treatment. 149: 619-29. PMID 25638397 DOI: 10.1007/S10549-015-3283-9  0.506
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