| Year |
Citation |
Score |
| 2023 |
Michl J, Monterisi S, White B, Blaszczak W, Hulikova A, Abdullayeva G, Bridges E, Yin Z, Bodmer WF, Swietach P. Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2. Cell Reports. 42: 112601. PMID 37270778 DOI: 10.1016/j.celrep.2023.112601 |
0.345 |
|
| 2022 |
Russell S, Xu L, Kam Y, Abrahams D, Ordway B, Lopez AS, Bui MM, Johnson J, Epstein T, Ruiz E, Lloyd MC, Swietach P, Verduzco D, Wojtkowiak J, Gillies RJ. Proton export upregulates aerobic glycolysis. Bmc Biology. 20: 163. PMID 35840963 DOI: 10.1186/s12915-022-01340-0 |
0.318 |
|
| 2022 |
Hulikova A, Park KC, Loonat AA, Gunadasa-Rohling M, Curtis MK, Chung YJ, Wilson A, Carr CA, Trafford AW, Fournier M, Moshnikova A, Andreev OA, Reshetnyak YK, Riley PR, Smart N, ... ... Swietach P, et al. Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart. Basic Research in Cardiology. 117: 17. PMID 35357563 DOI: 10.1007/s00395-022-00924-9 |
0.357 |
|
| 2021 |
Wilson AD, Richards MA, Curtis MK, Rohling M, Monterisi S, Loonat AA, Miller J, Ball V, Lewis A, Tyler D, Moshnikova A, Andreev OA, Reshetnyak YK, Carr C, Swietach P. Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH. Cardiovascular Research. PMID 34897412 DOI: 10.1093/cvr/cvab364 |
0.378 |
|
| 2020 |
Kandilci HB, Richards MA, Fournier M, Şimşek G, Chung YJ, Lakhal-Littleton S, Swietach P. Cardiomyocyte Na/H Exchanger-1 Activity Is Reduced in Hypoxia. Frontiers in Cardiovascular Medicine. 7: 617038. PMID 33585583 DOI: 10.3389/fcvm.2020.617038 |
0.352 |
|
| 2020 |
Swietach P. What is pH regulation, and why do cancer cells need it? Cancer Metastasis Reviews. 38: 5-15. PMID 30707328 DOI: 10.1007/s10555-018-09778-x |
0.408 |
|
| 2019 |
Richards MA, Simon JN, Ma R, Loonat AA, Crabtree MJ, Paterson DJ, Fahlman RP, Casadei B, Fliegel L, Swietach P. Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1. Cardiovascular Research. PMID 31742355 DOI: 10.1093/cvr/cvz311 |
0.392 |
|
| 2019 |
Michl J, Park KC, Swietach P. Evidence-based guidelines for controlling pH in mammalian live-cell culture systems. Communications Biology. 2: 144. PMID 31044169 DOI: 10.1038/s42003-019-0393-7 |
0.318 |
|
| 2018 |
Lee SH, McIntyre D, Honess D, Hulikova A, Pacheco-Torres J, Cerdán S, Swietach P, Harris AL, Griffiths JR. Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo. British Journal of Cancer. PMID 30206370 DOI: 10.1038/S41416-018-0216-5 |
0.449 |
|
| 2018 |
Şimşek G, Vaughan-Jones RD, Swietach P, Kandilci HB. Recovery from hypoxia-induced internalization of cardiac Na /H exchanger 1 requires an adequate intracellular store of antioxidants. Journal of Cellular Physiology. PMID 30191998 DOI: 10.1002/jcp.27268 |
0.614 |
|
| 2017 |
Garciarena CD, Malik A, Swietach P, Moreno AP, Vaughan-Jones RD. Distinct moieties underlie biphasic H+ gating of connexin43 channels, producing a pH optimum for intercellular communication. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29183963 DOI: 10.1096/fj.201700876R |
0.595 |
|
| 2017 |
Dovmark TH, Hulikova A, Niederer SA, Vaughan-Jones RD, Swietach P. Normoxic cells remotely regulate the acid-base balance of cells at the hypoxic core of connexin-coupled tumor growths. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28883041 DOI: 10.1096/fj.201700480R |
0.659 |
|
| 2017 |
Ford KL, Moorhouse EL, Bortolozzi M, Richards M, Swietach P, Vaughan-Jones RD. Regional acidosis locally inhibits but remotely stimulates Ca2+ waves in ventricular myocytes. Cardiovascular Research. PMID 28339694 DOI: 10.1093/cvr/cvx033 |
0.574 |
|
| 2016 |
McIntyre A, Hulikova A, Ledaki I, Snell C, Singleton D, Steers G, Seden P, Jones D, Bridges E, Wigfield S, Li JL, Russell A, Swietach P, Harris AL. Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth. Cancer Research. PMID 27197160 DOI: 10.1158/0008-5472.Can-15-1862 |
0.482 |
|
| 2016 |
Richards M, Lomas O, Jalink K, Ford KL, Vaughan-Jones RD, Lefkimmiatis K, Swietach P. Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes. Cardiovascular Research. PMID 27089919 DOI: 10.1093/cvr/cvw080 |
0.51 |
|
| 2015 |
Swietach P, Vaughan-Jones RD, Hulikova A, Niederer SA. Rebuttal from Pawel Swietach, Richard D. Vaughan-Jones, Alzbeta Hulikova and Steven A. Niederer. The Journal of Physiology. PMID 26568334 DOI: 10.1113/JP271240 |
0.442 |
|
| 2015 |
Hulikova A, Vaughan-Jones RD, Niederer SA, Swietach P. CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels. The Journal of Physiology. PMID 26568197 DOI: 10.1113/JP270013 |
0.514 |
|
| 2015 |
Hulikova A, Swietach P. Nuclear proton dynamics and interactions with calcium signaling. Journal of Molecular and Cellular Cardiology. 96: 26-37. PMID 26183898 DOI: 10.1016/j.yjmcc.2015.07.003 |
0.381 |
|
| 2015 |
Swietach P, Spitzer KW, Vaughan-Jones RD. Na⁺ ions as spatial intracellular messengers for co-ordinating Ca²⁺ signals during pH heterogeneity in cardiomyocytes. Cardiovascular Research. 105: 171-81. PMID 25514933 DOI: 10.1093/cvr/cvu251 |
0.664 |
|
| 2014 |
Hulikova A, Aveyard N, Harris AL, Vaughan-Jones RD, Swietach P. Intracellular carbonic anhydrase activity sensitizes cancer cell pH signaling to dynamic changes in CO2 partial pressure. The Journal of Biological Chemistry. 289: 25418-30. PMID 25059669 DOI: 10.1074/jbc.M114.547844 |
0.687 |
|
| 2014 |
Swietach P, Leem CH, Spitzer KW, Vaughan-Jones RD. Pumping Ca2+ up H+ gradients: a Ca2(+)-H+ exchanger without a membrane. The Journal of Physiology. 592: 3179-88. PMID 24514908 DOI: 10.1113/jphysiol.2013.265959 |
0.637 |
|
| 2014 |
Swietach P, Vaughan-Jones RD, Harris AL, Hulikova A. The chemistry, physiology and pathology of pH in cancer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130099. PMID 24493747 DOI: 10.1098/rstb.2013.0099 |
0.739 |
|
| 2014 |
Villafuerte FC, Swietach P, Youm JB, Ford K, Cardenas R, Supuran CT, Cobden PM, Rohling M, Vaughan-Jones RD. Facilitation by intracellular carbonic anhydrase of Na+ -HCO3- co-transport but not Na+ / H+ exchange activity in the mammalian ventricular myocyte. The Journal of Physiology. 592: 991-1007. PMID 24297849 DOI: 10.1113/jphysiol.2013.265439 |
0.669 |
|
| 2013 |
Gondi G, Mysliwietz J, Hulikova A, Jen JP, Swietach P, Kremmer E, Zeidler R. Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII. Cancer Research. 73: 6494-503. PMID 24030978 DOI: 10.1158/0008-5472.CAN-13-1110 |
0.309 |
|
| 2013 |
Swietach P, Youm JB, Saegusa N, Leem CH, Spitzer KW, Vaughan-Jones RD. Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E2064-73. PMID 23676270 DOI: 10.1073/pnas.1222433110 |
0.636 |
|
| 2013 |
Garciarena CD, Youm JB, Swietach P, Vaughan-Jones RD. H⁺-activated Na⁺ influx in the ventricular myocyte couples Ca²⁺-signalling to intracellular pH. Journal of Molecular and Cellular Cardiology. 61: 51-9. PMID 23602948 DOI: 10.1016/j.yjmcc.2013.04.008 |
0.669 |
|
| 2013 |
Schroeder MA, Ali MA, Hulikova A, Supuran CT, Clarke K, Vaughan-Jones RD, Tyler DJ, Swietach P. Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. Proceedings of the National Academy of Sciences of the United States of America. 110: E958-67. PMID 23431149 DOI: 10.1073/pnas.1213471110 |
0.598 |
|
| 2013 |
Garciarena CD, Ma YL, Swietach P, Huc L, Vaughan-Jones RD. Sarcolemmal localisation of Na+/H+ exchange and Na+-HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes. The Journal of Physiology. 591: 2287-306. PMID 23420656 DOI: 10.1113/jphysiol.2012.249664 |
0.666 |
|
| 2013 |
Hulikova A, Harris AL, Vaughan-Jones RD, Swietach P. Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia. Journal of Cellular Physiology. 228: 743-52. PMID 22949268 DOI: 10.1002/jcp.24221 |
0.706 |
|
| 2012 |
Swietach P, Hulikova A, Patiar S, Vaughan-Jones RD, Harris AL. Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin. Plos One. 7: e35949. PMID 22563426 DOI: 10.1371/journal.pone.0035949 |
0.666 |
|
| 2012 |
McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877 |
0.607 |
|
| 2012 |
Hulikova A, Harris AL, Vaughan-Jones RD, Swietach P. Acid-extrusion from tissue: the interplay between membrane transporters and pH buffers. Current Pharmaceutical Design. 18: 1331-7. PMID 22360560 |
0.706 |
|
| 2011 |
Hulikova A, Vaughan-Jones RD, Swietach P. Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths. The Journal of Biological Chemistry. 286: 13815-26. PMID 21345798 DOI: 10.1074/jbc.M111.219899 |
0.694 |
|
| 2011 |
Murri-Plesko MT, Hulikova A, Oosterwijk E, Scott AM, Zortea A, Harris AL, Ritter G, Old L, Bauer S, Swietach P, Renner C. Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. European Journal of Pharmacology. 657: 173-83. PMID 21315712 DOI: 10.1016/j.ejphar.2011.01.063 |
0.385 |
|
| 2010 |
Swietach P, Tiffert T, Mauritz JM, Seear R, Esposito A, Kaminski CF, Lew VL, Vaughan-Jones RD. Hydrogen ion dynamics in human red blood cells. The Journal of Physiology. 588: 4995-5014. PMID 20962000 DOI: 10.1113/Jphysiol.2010.197392 |
0.658 |
|
| 2010 |
Swietach P, Spitzer KW, Vaughan-Jones RD. Modeling calcium waves in cardiac myocytes: importance of calcium diffusion. Frontiers in Bioscience (Landmark Edition). 15: 661-80. PMID 20036839 DOI: 10.2741/3639 |
0.491 |
|
| 2010 |
Swietach P, Camelliti P, Hulikova A, Kohl P, Vaughan-Jones RD. Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes. Cardiovascular Research. 85: 729-38. PMID 19828673 DOI: 10.1093/Cvr/Cvp343 |
0.629 |
|
| 2009 |
Swietach P, Patiar S, Supuran CT, Harris AL, Vaughan-Jones RD. The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths. The Journal of Biological Chemistry. 284: 20299-310. PMID 19458084 DOI: 10.1074/jbc.M109.006478 |
0.73 |
|
| 2009 |
Huang WC, Swietach P, Vaughan-Jones RD, Glitsch MD. Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells. Cell Calcium. 45: 391-9. PMID 19249096 DOI: 10.1016/j.ceca.2009.01.002 |
0.621 |
|
| 2009 |
Vaughan-Jones RD, Spitzer KW, Swietach P. Intracellular pH regulation in heart. Journal of Molecular and Cellular Cardiology. 46: 318-31. PMID 19041875 DOI: 10.1016/j.yjmcc.2008.10.024 |
0.643 |
|
| 2008 |
Vaughan-Jones RD, Swietach P. Pushing and pulling the cardiac sodium/hydrogen exchanger. Circulation Research. 103: 773-5. PMID 18845814 DOI: 10.1161/CIRCRESAHA.108.186445 |
0.497 |
|
| 2008 |
Huang WC, Swietach P, Vaughan-Jones RD, Ansorge O, Glitsch MD. Extracellular acidification elicits spatially and temporally distinct Ca2+ signals. Current Biology : Cb. 18: 781-5. PMID 18485712 DOI: 10.1016/j.cub.2008.04.049 |
0.598 |
|
| 2008 |
Swietach P, Wigfield S, Cobden P, Supuran CT, Harris AL, Vaughan-Jones RD. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. The Journal of Biological Chemistry. 283: 20473-83. PMID 18482982 DOI: 10.1074/jbc.M801330200 |
0.705 |
|
| 2008 |
Swietach P, Wigfield S, Supuran CT, Harris AL, Vaughan-Jones RD. Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion. Bju International. 101: 22-4. PMID 18430118 DOI: 10.1111/j.1464-410X.2008.07644.x |
0.566 |
|
| 2008 |
Swietach P, Spitzer KW, Vaughan-Jones RD. Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low. Biophysical Journal. 95: 1412-27. PMID 18390622 DOI: 10.1529/biophysj.108.130385 |
0.57 |
|
| 2007 |
Swietach P, Vaughan-Jones RD, Harris AL. Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Reviews. 26: 299-310. PMID 17415526 DOI: 10.1007/s10555-007-9064-0 |
0.672 |
|
| 2007 |
Swietach P, Rossini A, Spitzer KW, Vaughan-Jones RD. H+ ion activation and inactivation of the ventricular gap junction: a basis for spatial regulation of intracellular pH. Circulation Research. 100: 1045-54. PMID 17363701 DOI: 10.1161/01.RES.0000264071.11619.47 |
0.665 |
|
| 2007 |
Swietach P, Spitzer KW, Vaughan-Jones RD. pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound. Biophysical Journal. 92: 641-53. PMID 17056723 DOI: 10.1529/biophysj.106.096560 |
0.68 |
|
| 2006 |
Vaughan-Jones RD, Villafuerte FC, Swietach P, Yamamoto T, Rossini A, Spitzer KW. pH-Regulated Na(+) influx into the mammalian ventricular myocyte: the relative role of Na(+)-H(+) exchange and Na(+)-HCO Co-transport. Journal of Cardiovascular Electrophysiology. 17: S134-S140. PMID 16686668 DOI: 10.1111/j.1540-8167.2006.00394.x |
0.616 |
|
| 2006 |
Vaughan-Jones RD, Spitzer KW, Swietach P. Spatial aspects of intracellular pH regulation in heart muscle. Progress in Biophysics and Molecular Biology. 90: 207-24. PMID 16125756 DOI: 10.1016/j.pbiomolbio.2005.06.004 |
0.686 |
|
| 2005 |
Swietach P, Vaughan-Jones RD. Spatial regulation of intracellular pH in the ventricular myocyte. Annals of the New York Academy of Sciences. 1047: 271-82. PMID 16093503 DOI: 10.1196/annals.1341.024 |
0.689 |
|
| 2005 |
Swietach P, Vaughan-Jones RD. Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes. The Journal of Physiology. 566: 793-806. PMID 15919716 DOI: 10.1113/jphysiol.2005.086165 |
0.622 |
|
| 2005 |
Swietach P, Leem CH, Spitzer KW, Vaughan-Jones RD. Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes. Biophysical Journal. 88: 3018-37. PMID 15653720 DOI: 10.1529/biophysj.104.051391 |
0.663 |
|
| 2005 |
Yamamoto T, Swietach P, Rossini A, Loh SH, Vaughan-Jones RD, Spitzer KW. Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig. The Journal of Physiology. 562: 455-75. PMID 15550467 DOI: 10.1113/jphysiol.2004.071068 |
0.605 |
|
| 2004 |
Swietach P, Vaughan-Jones RD. Novel method for measuring junctional proton permeation in isolated ventricular myocyte cell pairs. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2352-63. PMID 15242838 DOI: 10.1152/ajpheart.00528.2004 |
0.525 |
|
| 2003 |
Zaniboni M, Rossini A, Swietach P, Banger N, Spitzer KW, Vaughan-Jones RD. Proton permeation through the myocardial gap junction. Circulation Research. 93: 726-35. PMID 12958146 DOI: 10.1161/01.RES.0000093986.47383.CE |
0.624 |
|
| 2003 |
Ch'en FF, Dilworth E, Swietach P, Goddard RS, Vaughan-Jones RD. Temperature dependence of Na+-H+ exchange, Na+-HCO3- co-transport, intracellular buffering and intracellular pH in guinea-pig ventricular myocytes. The Journal of Physiology. 552: 715-26. PMID 12923205 DOI: 10.1113/jphysiol.2003.051888 |
0.632 |
|
| 2003 |
Swietach P, Zaniboni M, Stewart AK, Rossini A, Spitzer KW, Vaughan-Jones RD. Modelling intracellular H(+) ion diffusion. Progress in Biophysics and Molecular Biology. 83: 69-100. PMID 12865074 DOI: 10.1016/S0079-6107(03)00027-0 |
0.664 |
|
| 2003 |
Zaniboni M, Swietach P, Rossini A, Yamamoto T, Spitzer KW, Vaughan-Jones RD. Intracellular proton mobility and buffering power in cardiac ventricular myocytes from rat, rabbit, and guinea pig. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1236-46. PMID 12750065 DOI: 10.1152/ajpheart.00277.2003 |
0.663 |
|
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