| Year |
Citation |
Score |
| 2021 |
Jiang W, Lin YC, Botello-Smith W, Contreras J, Harris AL, Maragliano L, Luo YL. Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning. Biophysical Journal. PMID 34214529 DOI: 10.1016/j.bpj.2021.06.024 |
0.494 |
|
| 2021 |
Gaete PS, Contreras JE. A method for assessing ionic and molecular permeation in connexin hemichannels. Methods in Enzymology. 654: 271-293. PMID 34120717 DOI: 10.1016/bs.mie.2021.01.009 |
0.377 |
|
| 2021 |
Seo JH, Dalal MS, Contreras JE. Pannexin-1 Channels as Mediators of Neuroinflammation. International Journal of Molecular Sciences. 22. PMID 34068881 DOI: 10.3390/ijms22105189 |
0.311 |
|
| 2021 |
Narahari AK, Kreutzberger AJB, Gaete PS, Chiu YH, Leonhardt SA, Medina CB, Jin X, Oleniacz PW, Kiessling V, Barrett PQ, Ravichandran KS, Yeager M, Contreras JE, Tamm LK, Bayliss D. ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels. Elife. 10. PMID 33410749 DOI: 10.7554/eLife.64787 |
0.442 |
|
| 2020 |
Gaete PS, Lillo MA, López W, Liu Y, Jiang W, Luo Y, Harris AL, Contreras JE. A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels. The Journal of General Physiology. 152. PMID 33074302 DOI: 10.1085/jgp.202012607 |
0.552 |
|
| 2020 |
Naulin PA, Lozano B, Fuentes C, Liu Y, Schmidt C, Contreras JE, Barrera NP. Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by AFM imaging. The Journal of Biological Chemistry. PMID 32887797 DOI: 10.1074/Jbc.Ra119.012128 |
0.422 |
|
| 2020 |
Seo JH, Dalal MS, Calderon F, Contreras JE. Myeloid Pannexin-1 mediates acute leukocyte infiltration and leads to worse outcomes after brain trauma. Journal of Neuroinflammation. 17: 245. PMID 32819386 DOI: 10.1186/s12974-020-01917-y |
0.353 |
|
| 2020 |
Gaete PS, Contreras JE. Taking a close look at a large-pore channel. Elife. 9. PMID 32228857 DOI: 10.7554/eLife.56114 |
0.369 |
|
| 2019 |
Gaete PS, Contreras JE. Uncoupled permeation through large-pore channels: ions and molecules don't always ride together. The Journal of Physiology. PMID 31785170 DOI: 10.1113/JP279263 |
0.31 |
|
| 2018 |
Valdez Capuccino JM, Chatterjee P, García IE, Botello-Smith WM, Zhang H, Harris AL, Luo Y, Contreras JE. The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening. The Journal of General Physiology. PMID 30530766 DOI: 10.1085/Jgp.201812219 |
0.502 |
|
| 2018 |
García IE, Villanelo F, Contreras GF, Pupo A, Pinto BI, Contreras JE, Pérez-Acle T, Alvarez O, Latorre R, Martínez AD, González C. The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels. The Journal of General Physiology. PMID 29643172 DOI: 10.1085/Jgp.201711782 |
0.308 |
|
| 2018 |
Garg C, Seo JH, Ramachandran J, Loh JM, Calderon F, Contreras JE. Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice. Journal of Neuroinflammation. 15: 42. PMID 29439712 DOI: 10.1186/s12974-018-1069-9 |
0.306 |
|
| 2016 |
Lopez W, Ramachandran J, Alsamarah A, Luo Y, Harris AL, Contreras JE. Mechanism of gating by calcium in connexin hemichannels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872296 DOI: 10.1073/Pnas.1609378113 |
0.509 |
|
| 2015 |
Tong X, Lopez W, Ramachandran J, Ayad WA, Liu Y, Lopez-Rodriguez A, Harris AL, Contreras JE. Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules. The Journal of General Physiology. 146: 245-54. PMID 26324677 DOI: 10.1085/Jgp.201511375 |
0.582 |
|
| 2015 |
García IE, Maripillán J, Jara O, Ceriani R, Palacios-Muñoz A, Ramachandran J, Olivero P, Perez-Acle T, González C, Sáez JC, Contreras JE, Martínez AD. Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43. The Journal of Investigative Dermatology. 135: 1338-47. PMID 25625422 DOI: 10.1038/Jid.2015.20 |
0.531 |
|
| 2014 |
Harris AL, Contreras JE. Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing. Frontiers in Physiology. 5: 113. PMID 24744733 DOI: 10.3389/Fphys.2014.00113 |
0.612 |
|
| 2014 |
Lopez W, Liu Y, Harris AL, Contreras JE. Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels. Channels (Austin, Tex.). 8: 1-4. PMID 24126106 DOI: 10.4161/Chan.26789 |
0.444 |
|
| 2013 |
Lopez W, Gonzalez J, Liu Y, Harris AL, Contreras JE. Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y). The Journal of General Physiology. 142: 23-35. PMID 23797420 DOI: 10.1085/Jgp.201210893 |
0.514 |
|
| 2013 |
Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22. PMID 23479636 DOI: 10.1073/Pnas.1219611110 |
0.399 |
|
| 2010 |
Contreras JE, Chen J, Lau AY, Jogini V, Roux B, Holmgren M. Voltage profile along the permeation pathway of an open channel. Biophysical Journal. 99: 2863-9. PMID 21044583 DOI: 10.1016/J.Bpj.2010.08.053 |
0.323 |
|
| 2008 |
Contreras JE, Srikumar D, Holmgren M. Gating at the selectivity filter in cyclic nucleotide-gated channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 3310-4. PMID 18287006 DOI: 10.1073/Pnas.0709809105 |
0.362 |
|
| 2006 |
Contreras JE, Holmgren M. Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate. The Journal of General Physiology. 127: 481-94. PMID 16606688 DOI: 10.1085/Jgp.200509440 |
0.423 |
|
| 2004 |
Contreras JE, Sánchez HA, Véliz LP, Bukauskas FF, Bennett MV, Sáez JC. Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Research. Brain Research Reviews. 47: 290-303. PMID 15572178 DOI: 10.1016/J.Brainresrev.2004.08.002 |
0.7 |
|
| 2003 |
Contreras JE, Sáez JC, Bukauskas FF, Bennett MV. Functioning of cx43 hemichannels demonstrated by single channel properties. Cell Communication & Adhesion. 10: 245-9. PMID 14681024 DOI: 10.1080/Cac.10.4-6.245.249 |
0.7 |
|
| 2003 |
Bennett MV, Contreras JE, Bukauskas FF, Sáez JC. New roles for astrocytes: gap junction hemichannels have something to communicate. Trends in Neurosciences. 26: 610-7. PMID 14585601 DOI: 10.1016/J.Tins.2003.09.008 |
0.707 |
|
| 2003 |
Contreras JE, Sáez JC, Bukauskas FF, Bennett MV. Gating and regulation of connexin 43 (Cx43) hemichannels. Proceedings of the National Academy of Sciences of the United States of America. 100: 11388-93. PMID 13130072 DOI: 10.1073/Pnas.1434298100 |
0.689 |
|
| 2003 |
Sáez JC, Contreras JE, Bukauskas FF, Retamal MA, Bennett MV. Gap junction hemichannels in astrocytes of the CNS. Acta Physiologica Scandinavica. 179: 9-22. PMID 12940934 DOI: 10.1046/J.1365-201X.2003.01196.X |
0.674 |
|
| 2002 |
Branes MC, Contreras JE, Sáez JC. Activation of human polymorphonuclear cells induces formation of functional gap junctions and expression of connexins. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 8: BR313-23. PMID 12165735 |
0.531 |
|
| 2002 |
De Maio A, Vega VL, Contreras JE. Gap junctions, homeostasis, and injury. Journal of Cellular Physiology. 191: 269-82. PMID 12012322 DOI: 10.1002/jcp.10108 |
0.346 |
|
| 2002 |
Contreras JE, Sánchez HA, Eugenin EA, Speidel D, Theis M, Willecke K, Bukauskas FF, Bennett MV, Sáez JC. Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proceedings of the National Academy of Sciences of the United States of America. 99: 495-500. PMID 11756680 DOI: 10.1073/Pnas.012589799 |
0.637 |
|
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