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Chien-Chi Lin, Ph.D. - Publications

Affiliations: 
2010-2024 Biomedical Engineering Purdue University, West Lafayette, IN, United States 
Area:
Biomaterials, Hydrogels, Tissue Engineering, Cancer Engineering
Website:
www.chienchilin.org
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68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lin CC, Frahm E, Afolabi FO. Orthogonally Crosslinked Gelatin-Norbornene Hydrogels for Biomedical Applications. Macromolecular Bioscience. e2300371. PMID 37748778 DOI: 10.1002/mabi.202300371  0.452
2023 Arkenberg MR, Ueda Y, Hashino E, Lin CC. Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cells. Stem Cell Research & Therapy. 14: 223. PMID 37649117 DOI: 10.1186/s13287-023-03457-7  0.797
2023 Duong VT, Lin CC. Digital Light Processing 3D Bioprinting of Gelatin-Norbornene Hydrogel for Enhanced Vascularization. Macromolecular Bioscience. e2300213. PMID 37536347 DOI: 10.1002/mabi.202300213  0.349
2023 Arkenberg MR, Ueda Y, Hashino E, Lin CC. Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cells. Research Square. PMID 37163050 DOI: 10.21203/rs.3.rs-2557598/v1  0.796
2023 Lin FY, Chang CY, Nguyen H, Li H, Fishel ML, Lin CC. Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions. Materials Today. Bio. 19: 100576. PMID 36816601 DOI: 10.1016/j.mtbio.2023.100576  0.74
2023 Kim MH, Lin CC. Poly(ethylene glycol)-Norbornene as a Photoclick Bioink for Digital Light Processing 3D Bioprinting. Acs Applied Materials & Interfaces. PMID 36608274 DOI: 10.1021/acsami.2c20098  0.364
2022 Dimmitt NH, Arkenberg MR, de Lima Perini MM, Li J, Lin CC. Hydrolytically Degradable PEG-Based Inverse Electron Demand Diels-Alder Click Hydrogels. Acs Biomaterials Science & Engineering. PMID 36074814 DOI: 10.1021/acsbiomaterials.2c00714  0.819
2022 Arkenberg MR, Koehler K, Lin CC. Heparinized Gelatin-Based Hydrogels for Differentiation of Induced Pluripotent Stem Cells. Biomacromolecules. 23: 4141-4152. PMID 36074748 DOI: 10.1021/acs.biomac.2c00585  0.831
2022 Jiang Z, Lin FY, Jiang K, Nguyen H, Chang CY, Lin CC. Dissolvable microgel-templated macroporous hydrogels for controlled cell assembly. Materials Science & Engineering. C, Materials For Biological Applications. 112712. PMID 35581097 DOI: 10.1016/j.msec.2022.112712  0.775
2021 Lin FY, Lin CC. Facile Synthesis of Rapidly Degrading PEG-Based Thiol-Norbornene Hydrogels. Acs Macro Letters. 10: 341-345. PMID 35549061 DOI: 10.1021/acsmacrolett.1c00056  0.775
2021 Lin FY, Dimmitt NH, Perini MML, Li J, Lin CC. Injectable Acylhydrazone-linked RAFT Polymer Hydrogels for Sustained Protein Release and Cell Encapsulation. Advanced Healthcare Materials. e2101284. PMID 34608768 DOI: 10.1002/adhm.202101284  0.725
2021 Kim MH, Nguyen H, Chang CY, Lin CC. Dual Functionalization of Gelatin for Orthogonal and Dynamic Hydrogel Cross-Linking. Acs Biomaterials Science & Engineering. PMID 34370445 DOI: 10.1021/acsbiomaterials.1c00709  0.412
2021 Chang CY, Johnson HC, Babb O, Fishel ML, Lin CC. Biomimetic stiffening of cell-laden hydrogels via sequential thiol-ene and hydrazone click reactions. Acta Biomaterialia. PMID 34087443 DOI: 10.1016/j.actbio.2021.05.054  0.382
2021 Kim MH, Lin CC. Assessing monocyte phenotype in poly(-glutamic acid) hydrogels formed by orthogonal thiol-norbornene chemistry. Biomedical Materials (Bristol, England). 16. PMID 34037542 DOI: 10.1088/1748-605X/ac01b0  0.408
2021 Chang CY, Lin CC. Hydrogel Models with Stiffness Gradients for Interrogating Pancreatic Cancer Cell Fate. Bioengineering (Basel, Switzerland). 8. PMID 33805737 DOI: 10.3390/bioengineering8030037  0.332
2021 Nguyen HD, Sun X, Yokota H, Lin CC. Probing Osteocyte Functions in Gelatin Hydrogels with Tunable Viscoelasticity. Biomacromolecules. PMID 33543929 DOI: 10.1021/acs.biomac.0c01476  0.36
2020 Arkenberg MR, Dimmitt NH, Johnson HC, Koehler KR, Lin CC. Dynamic Click Hydrogels for Xeno-Free Culture of Induced Pluripotent Stem Cells. Advanced Biosystems. e2000129. PMID 32924337 DOI: 10.1002/adbi.202000129  0.834
2020 Arkenberg MR, Nguyen HD, Lin CC. Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels. Journal of Materials Chemistry. B. PMID 32692329 DOI: 10.1039/d0tb01429j  0.823
2019 Hudson BN, Dawes CS, Liu HY, DImmitt N, Chen F, Konig H, Lin CC. Stabilization of enzyme-immobilized hydrogels for extended hypoxic cell culture. Emergent Materials. 2: 263-272. PMID 37502125 DOI: 10.1007/s42247-019-00038-4  0.712
2019 Nguyen HD, Liu HY, Hudson BN, Lin CC. Enzymatic Cross-Linking of Dynamic Thiol-Norbornene Click Hydrogels. Acs Biomaterials Science & Engineering. 5: 1247-1256. PMID 33304998 DOI: 10.1021/acsbiomaterials.8b01607  0.788
2019 Liu HY, Lin CC. A Diffusion-Reaction Model for Predicting Enzyme-Mediated Dynamic Hydrogel Stiffening. Gels (Basel, Switzerland). 5. PMID 30871250 DOI: 10.3390/gels5010017  0.729
2018 Arkenberg MR, Moore DM, Lin CC. Dynamic control of hydrogel crosslinking via sortase-mediated reversible transpeptidation. Acta Biomaterialia. PMID 30415064 DOI: 10.1016/j.actbio.2018.11.011  0.844
2018 Liu HY, Nguyen HD, Lin CC. Dynamic PEG-Peptide Hydrogels via Visible Light and FMN-Induced Tyrosine Dimerization. Advanced Healthcare Materials. e1800954. PMID 30369100 DOI: 10.1002/adhm.201800954  0.773
2018 Lin CC, Korc M. Designer hydrogels: Shedding light on the physical chemistry of the pancreatic cancer microenvironment. Cancer Letters. PMID 30118843 DOI: 10.1016/j.canlet.2018.08.008  0.319
2018 Liu HY, Korc M, Lin CC. Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma. Biomaterials. 160: 24-36. PMID 29353105 DOI: 10.1016/j.biomaterials.2018.01.012  0.754
2017 Arkenberg MR, Lin CC. Orthogonal enzymatic reactions for rapid crosslinking and dynamic tuning of PEG-peptide hydrogels. Biomaterials Science. PMID 28991963 DOI: 10.1039/c7bm00691h  0.835
2017 Dawes CS, Konig H, Lin CC. Enzyme-immobilized hydrogels to create hypoxia for in vitro cancer cell culture. Journal of Biotechnology. PMID 28284922 DOI: 10.1016/j.jbiotec.2017.03.007  0.337
2017 Shih H, Liu HY, Lin CC. Improving gelation efficiency and cytocompatibility of visible light polymerized thiol-norbornene hydrogels via addition of soluble tyrosine. Biomaterials Science. PMID 28174779 DOI: 10.1039/c6bm00778c  0.835
2016 Shih H, Lin CC. Tuning stiffness of cell-laden hydrogel via host-guest interactions. Journal of Materials Chemistry. B. 4: 4969-4974. PMID 32264023 DOI: 10.1039/c6tb00890a  0.795
2016 Shih H, Greene T, Korc M, Lin CC. Modular and Adaptable Tumor Niche Prepared from Visible Light Initiated Thiol-Norbornene Photopolymerization. Biomacromolecules. 17: 3872-3882. PMID 27936722 DOI: 10.1021/acs.biomac.6b00931  0.793
2016 Liu HY, Greene T, Lin TY, Dawes CS, Korc M, Lin CC. Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells. Acta Biomaterialia. PMID 27769941 DOI: 10.1016/j.actbio.2016.10.027  0.81
2015 Greene T, Lin CC. Modular Cross-Linking of Gelatin-Based Thiol-Norbornene Hydrogels for 3D Culture of Hepatocellular Carcinoma Cells. Acs Biomaterials Science & Engineering. 1: 1314-1323. PMID 33429678 DOI: 10.1021/acsbiomaterials.5b00436  0.442
2015 Lin TY, Bragg JC, Lin CC. Designing Visible Light-Cured Thiol-Acrylate Hydrogels for Studying the HIPPO Pathway Activation in Hepatocellular Carcinoma Cells. Macromolecular Bioscience. PMID 26709469 DOI: 10.1002/Mabi.201500361  0.649
2015 Shih H, Mirmira RG, Lin CC. Visible light-initiated interfacial thiol-norbornene photopolymerization for forming islet surface conformal coating. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 3: 170-175. PMID 26509035 DOI: 10.1039/C4TB01593B  0.731
2015 Lin CC. Recent advances in crosslinking chemistry of biomimetic poly(ethylene glycol) hydrogels. Rsc Advances. 5: 39844-398583. PMID 26029357 DOI: 10.1039/C5RA05734E  0.471
2015 Shih H, Lin CC. Photoclick Hydrogels Prepared from Functionalized Cyclodextrin and Poly(ethylene glycol) for Drug Delivery and in Situ Cell Encapsulation. Biomacromolecules. 16: 1915-23. PMID 25996903 DOI: 10.1021/acs.biomac.5b00471  0.794
2015 Lin CC, Ki CS, Shih H. Thiol-norbornene photo-click hydrogels for tissue engineering applications. Journal of Applied Polymer Science. 132. PMID 25558088 DOI: 10.1002/app.41563  0.804
2014 Mũnoz Z, Shih H, Lin CC. Gelatin hydrogels formed by orthogonal thiol-norbornene photochemistry for cell encapsulation. Biomaterials Science. 2: 1063-1072. PMID 32482001 DOI: 10.1039/c4bm00070f  0.799
2014 Ki CS, Lin TY, Korc M, Lin CC. Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance. Biomaterials. 35: 9668-77. PMID 25176061 DOI: 10.1016/j.biomaterials.2014.08.014  0.626
2014 Lin TY, Ki CS, Lin CC. Manipulating hepatocellular carcinoma cell fate in orthogonally cross-linked hydrogels. Biomaterials. 35: 6898-906. PMID 24857292 DOI: 10.1016/J.Biomaterials.2014.04.118  0.606
2014 Hao Y, Lin CC. Degradable thiol-acrylate hydrogels as tunable matrices for three-dimensional hepatic culture. Journal of Biomedical Materials Research. Part A. 102: 3813-27. PMID 24288169 DOI: 10.1002/jbm.a.35044  0.46
2014 Hao Y, Shih H, Muňoz Z, Kemp A, Lin CC. Visible light cured thiol-vinyl hydrogels with tunable degradation for 3D cell culture. Acta Biomaterialia. 10: 104-14. PMID 24021231 DOI: 10.1016/j.actbio.2013.08.044  0.81
2013 Hamamura K, Zhang P, Zhao L, Shim JW, Chen A, Dodge TR, Wan Q, Shih H, Na S, Lin CC, Sun HB, Yokota H. Knee loading reduces MMP13 activity in the mouse cartilage. Bmc Musculoskeletal Disorders. 14: 312. PMID 24180431 DOI: 10.1186/1471-2474-14-312  0.695
2013 Ki CS, Shih H, Lin CC. Facile preparation of photodegradable hydrogels by photopolymerization. Polymer. 54: 2115-2122. PMID 23894212 DOI: 10.1016/j.polymer.2013.02.018  0.796
2013 Ki CS, Shih H, Lin CC. Effect of 3D matrix compositions on the efficacy of EGFR inhibition in pancreatic ductal adenocarcinoma cells. Biomacromolecules. 14: 3017-26. PMID 23889305 DOI: 10.1021/bm4004496  0.793
2013 Raza A, Lin CC. The influence of matrix degradation and functionality on cell survival and morphogenesis in PEG-based hydrogels. Macromolecular Bioscience. 13: 1048-58. PMID 23776086 DOI: 10.1002/mabi.201300044  0.437
2013 Raza A, Ki CS, Lin CC. The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D. Biomaterials. 34: 5117-27. PMID 23602364 DOI: 10.1016/j.biomaterials.2013.03.086  0.404
2013 Shih H, Lin CC. Visible-light-mediated thiol-ene hydrogelation using eosin-Y as the only photoinitiator. Macromolecular Rapid Communications. 34: 269-73. PMID 23386583 DOI: 10.1002/marc.201200605  0.776
2013 Shih H, Fraser AK, Lin CC. Interfacial thiol-ene photoclick reactions for forming multilayer hydrogels. Acs Applied Materials & Interfaces. 5: 1673-80. PMID 23384151 DOI: 10.1021/am302690t  0.772
2012 Raza A, Lin CC. Generation and recovery of β-cell spheroids from step-growth PEG-peptide hydrogels. Journal of Visualized Experiments : Jove. e50081. PMID 23241531 DOI: 10.3791/50081  0.483
2012 Shih H, Lin CC. Cross-linking and degradation of step-growth hydrogels formed by thiol-ene photoclick chemistry. Biomacromolecules. 13: 2003-12. PMID 22708824 DOI: 10.1021/bm300752j  0.79
2012 Bernard AB, Lin CC, Anseth KS. A microwell cell culture platform for the aggregation of pancreatic β-cells. Tissue Engineering. Part C, Methods. 18: 583-92. PMID 22320435 DOI: 10.1089/Ten.Tec.2011.0504  0.785
2011 Lin CC, Raza A, Shih H. PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids. Biomaterials. 32: 9685-95. PMID 21924490 DOI: 10.1016/j.biomaterials.2011.08.083  0.819
2011 Lin CC, Anseth KS. Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing beta-cell function. Proceedings of the National Academy of Sciences of the United States of America. 108: 6380-5. PMID 21464290 DOI: 10.1073/pnas.1014026108  0.659
2011 McCall JD, Lin CC, Anseth KS. Affinity peptides protect transforming growth factor beta during encapsulation in poly(ethylene glycol) hydrogels. Biomacromolecules. 12: 1051-7. PMID 21375234 DOI: 10.1021/Bm101379V  0.813
2011 Anderson SB, Lin CC, Kuntzler DV, Anseth KS. The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels. Biomaterials. 32: 3564-74. PMID 21334063 DOI: 10.1016/j.biomaterials.2011.01.064  0.704
2010 Aimetti AA, Shoemaker RK, Lin CC, Anseth KS. On-resin peptide macrocyclization using thiol-ene click chemistry. Chemical Communications (Cambridge, England). 46: 4061-3. PMID 20379591 DOI: 10.1039/C001375G  0.788
2010 Lin CC, Boyer PD, Aimetti AA, Anseth KS. Regulating MCP-1 diffusion in affinity hydrogels for enhancing immuno-isolation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 384-91. PMID 19951731 DOI: 10.1016/J.Jconrel.2009.11.022  0.834
2009 Lin CC, Anseth KS. Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels. Advanced Functional Materials. 19: 2325. PMID 20148198 DOI: 10.1002/adfm.200900107  0.654
2009 Lin CC, Anseth KS. Glucagon-like peptide-1 functionalized PEG hydrogels promote survival and function of encapsulated pancreatic beta-cells. Biomacromolecules. 10: 2460-7. PMID 19586041 DOI: 10.1021/bm900420f  0.683
2009 Lin CC, Metters AT, Anseth KS. Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials. 30: 4907-14. PMID 19560813 DOI: 10.1016/j.biomaterials.2009.05.083  0.814
2009 Lin CC, Anseth KS. PEG hydrogels for the controlled release of biomolecules in regenerative medicine. Pharmaceutical Research. 26: 631-43. PMID 19089601 DOI: 10.1007/s11095-008-9801-2  0.679
2008 Lin CC, Metters AT. Bifunctional monolithic affinity hydrogels for dual-protein delivery. Biomacromolecules. 9: 789-95. PMID 18257528 DOI: 10.1021/bm700940w  0.805
2008 Lin CC, Sawicki SM, Metters AT. Free-radical-mediated protein inactivation and recovery during protein photoencapsulation. Biomacromolecules. 9: 75-83. PMID 18088094 DOI: 10.1021/bm700782c  0.804
2007 Lin CC, Metters AT. Metal-chelating affinity hydrogels for sustained protein release. Journal of Biomedical Materials Research. Part A. 83: 954-64. PMID 17580324 DOI: 10.1002/jbm.a.31282  0.783
2006 Lin CC, Metters AT. Hydrogels in controlled release formulations: network design and mathematical modeling. Advanced Drug Delivery Reviews. 58: 1379-408. PMID 17081649 DOI: 10.1016/j.addr.2006.09.004  0.801
2006 Lin CC, Metters AT. Enhanced protein delivery from photopolymerized hydrogels using a pseudospecific metal chelating ligand. Pharmaceutical Research. 23: 614-22. PMID 16397740 DOI: 10.1007/s11095-005-9395-x  0.792
2005 Lin CC, Co CC, Ho CC. Micropatterning proteins and cells on polylactic acid and poly(lactide-co-glycolide). Biomaterials. 26: 3655-62. PMID 15621256 DOI: 10.1016/J.Biomaterials.2004.09.051  0.311
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