| Year |
Citation |
Score |
| 2018 |
Islam W, Fang J, Imamura T, Etrych T, Subr V, Ulbrich K, Maeda H. Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines. Molecular Cancer Therapeutics. PMID 30232144 DOI: 10.1158/1535-7163.MCT-18-0696 |
0.328 |
|
| 2018 |
Chytil P, Šírová M, Kudláčová J, Říhová B, Ulbrich K, Etrych T. Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release. Molecular Pharmaceutics. 15: 3654-3663. PMID 29543465 DOI: 10.1021/acs.molpharmaceut.8b00156 |
0.573 |
|
| 2017 |
Islam W, Fang J, Etrych T, Chytil P, Ulbrich K, Sakoguchi A, Kusakabe K, Maeda H. HPMA Copolymer Conjugate with Pirarubicin: In Vitro and Ex Vivo Stability and Drug Release study. International Journal of Pharmaceutics. PMID 29133205 DOI: 10.1016/j.ijpharm.2017.11.011 |
0.442 |
|
| 2017 |
Chytil P, Koziolová E, Etrych T, Ulbrich K. HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release. Macromolecular Bioscience. 18. PMID 28805040 DOI: 10.1002/mabi.201700209 |
0.542 |
|
| 2017 |
Etrych T, Tsukigawa K, Nakamura H, Chytil P, Fang J, Ulbrich K, Otagiri M, Maeda H. Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28528285 DOI: 10.1016/j.ejps.2017.05.031 |
0.314 |
|
| 2016 |
Nakamura H, Koziolová E, Chytil P, Tsukigawa K, Fang J, Haratake M, Ulbrich K, Etrych T, Maeda H. Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin. Molecular Pharmaceutics. 13: 4106-4115. PMID 27934482 DOI: 10.1021/acs.molpharmaceut.6b00697 |
0.509 |
|
| 2016 |
Lomkova EA, Chytil P, Janoušková O, Mueller T, Lucas H, Filippov SK, Trhlíková O, Aleshunin PA, Skorik YA, Ulbrich K, Etrych T. Biodegradable micellar HPMA-based polymer-drug conjugates with betulinic acid for passive tumor targeting. Biomacromolecules. PMID 27636143 DOI: 10.1021/acs.biomac.6b00947 |
0.517 |
|
| 2016 |
Maeda H, Fang J, Ulbrich K, Etrych T, Nakamura H. [Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 43: 549-57. PMID 27210083 |
0.378 |
|
| 2016 |
Koziolová E, Janoušková O, Cuchalová L, Hvězdová Z, Hraběta J, Eckschlager T, Sivák L, Ulbrich K, Etrych T, Šubr V. Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 233: 136-46. PMID 27189135 DOI: 10.1016/j.jconrel.2016.05.036 |
0.481 |
|
| 2016 |
Ulbrich K, Holá K, Šubr V, Bakandritsos A, Tuček J, Zbořil R. Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies. Chemical Reviews. 116: 5338-431. PMID 27109701 DOI: 10.1021/acs.chemrev.5b00589 |
0.534 |
|
| 2016 |
Jäger E, Höcherl A, Janoušková O, Jäger A, Hrubý M, Konefał R, Netopilik M, Pánek J, Šlouf M, Ulbrich K, Štěpánek P. Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications. Nanoscale. 8: 6958-63. PMID 26961769 DOI: 10.1039/c6nr00791k |
0.663 |
|
| 2015 |
Tomalova B, Sirova M, Rossmann P, Pola R, Strohalm J, Chytil P, Cerny V, Tomala J, Kabesova M, Rihova B, Ulbrich K, Etrych T, Kovar M. The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia. Journal of Controlled Release : Official Journal of the Controlled Release Society. 223: 1-10. PMID 26708020 DOI: 10.1016/j.jconrel.2015.12.023 |
0.473 |
|
| 2015 |
Laga R, Janoušková O, Ulbrich K, Pola R, Blažková J, Filippov SK, Etrych T, Pechar M. Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics. Biomacromolecules. 16: 2493-505. PMID 26153904 DOI: 10.1021/acs.biomac.5b00764 |
0.588 |
|
| 2015 |
Chytil P, Koziolová E, Janoušková O, Kostka L, Ulbrich K, Etrych T. Synthesis and Properties of Star HPMA Copolymer Nanocarriers Synthesised by RAFT Polymerisation Designed for Selective Anticancer Drug Delivery and Imaging. Macromolecular Bioscience. 15: 839-50. PMID 25731143 DOI: 10.1002/mabi.201400510 |
0.508 |
|
| 2015 |
Studenovský M, Sedláček O, Hrubý M, Pánek J, Ulbrich K. Multi-responsive polymer micelles as ellipticine delivery carriers for cancer therapy. Anticancer Research. 35: 753-7. PMID 25667454 |
0.69 |
|
| 2014 |
Etrych T, Subr V, Laga R, Ríhová B, Ulbrich K. Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 58: 1-12. PMID 24632485 DOI: 10.1016/j.ejps.2014.02.016 |
0.516 |
|
| 2014 |
Prill JM, Subr V, Pasquarelli N, Engler T, Hoffmeister A, Kochanek S, Ulbrich K, Kreppel F. Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo. Plos One. 9: e82716. PMID 24475024 DOI: 10.1371/journal.pone.0082716 |
0.302 |
|
| 2014 |
Nakamura H, Etrych T, Chytil P, Ohkubo M, Fang J, Ulbrich K, Maeda H. Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage. Journal of Controlled Release : Official Journal of the Controlled Release Society. 174: 81-7. PMID 24269967 DOI: 10.1016/j.jconrel.2013.11.011 |
0.392 |
|
| 2013 |
Quan L, Zhang Y, Crielaard BJ, Dusad A, Lele SM, Rijcken CJF, Metselaar JM, Kostková H, Etrych T, Ulbrich K, Kiessling F, Mikuls TR, Hennink WE, Storm G, Lammers T, et al. Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes. Acs Nano. 8: 458-466. PMID 24341611 DOI: 10.1021/nn4048205 |
0.342 |
|
| 2013 |
Carlisle R, Choi J, Bazan-Peregrino M, Laga R, Subr V, Kostka L, Ulbrich K, Coussios CC, Seymour LW. Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound. Journal of the National Cancer Institute. 105: 1701-10. PMID 24168971 DOI: 10.1093/jnci/djt305 |
0.331 |
|
| 2013 |
Filippov SK, Franklin JM, Konarev PV, Chytil P, Etrych T, Bogomolova A, Dyakonova M, Papadakis CM, Radulescu A, Ulbrich K, Stepanek P, Svergun DI. Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study. Biomacromolecules. 14: 4061-70. PMID 24083567 DOI: 10.1021/bm401186z |
0.673 |
|
| 2013 |
Kostková H, Etrych T, Ríhová B, Kostka L, Starovoytová L, Kovář M, Ulbrich K. HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy. Macromolecular Bioscience. 13: 1648-60. PMID 24031022 DOI: 10.1002/mabi.201300288 |
0.497 |
|
| 2013 |
Sedláček O, Studenovský M, Větvička D, Ulbrich K, Hrubý M. Fine tuning of the pH-dependent drug release rate from polyHPMA-ellipticinium conjugates. Bioorganic & Medicinal Chemistry. 21: 5669-72. PMID 23941688 DOI: 10.1016/j.bmc.2013.07.038 |
0.68 |
|
| 2013 |
Chytil P, Hoffmann S, Schindler L, Kostka L, Ulbrich K, Caysa H, Mueller T, Mäder K, Etrych T. Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 504-12. PMID 23697767 DOI: 10.1016/j.jconrel.2013.05.008 |
0.578 |
|
| 2013 |
Pola R, Laga R, Ulbrich K, Sieglová I, Král V, Fábry M, Kabešová M, Kovář M, Pechar M. Polymer therapeutics with a coiled coil motif targeted against murine bcl1 leukemia. Biomacromolecules. 14: 881-9. PMID 23373696 DOI: 10.1021/bm3019592 |
0.366 |
|
| 2013 |
Jäger E, Jäger A, Chytil P, Etrych T, Ríhová B, Giacomelli FC, Stěpánek P, Ulbrich K. Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester. Journal of Controlled Release : Official Journal of the Controlled Release Society. 165: 153-61. PMID 23178950 DOI: 10.1016/j.jconrel.2012.11.009 |
0.639 |
|
| 2012 |
Talelli M, Oliveira S, Rijcken CJ, Pieters EH, Etrych T, Ulbrich K, van Nostrum RC, Storm G, Hennink WE, Lammers T. Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy. Biomaterials. 34: 1255-60. PMID 23122804 DOI: 10.1016/j.biomaterials.2012.09.064 |
0.337 |
|
| 2012 |
Studenovsky M, Pola R, Pechar M, Etrych T, Ulbrich K, Kovar L, Kabesova M, Rihova B. Polymer Carriers for Anticancer Drugs Targeted to EGF Receptor Macromolecular Bioscience. 12: 1714-1720. PMID 23077133 DOI: 10.1002/mabi.201200270 |
0.417 |
|
| 2012 |
Filippov SK, Chytil P, Konarev PV, Dyakonova M, Papadakis C, Zhigunov A, Plestil J, Stepanek P, Etrych T, Ulbrich K, Svergun DI. Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system. Biomacromolecules. 13: 2594-604. PMID 22793269 DOI: 10.1021/bm3008555 |
0.629 |
|
| 2012 |
Etrych T, Subr V, Strohalm J, Sírová M, Ríhová B, Ulbrich K. HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 346-54. PMID 22759979 DOI: 10.1016/j.jconrel.2012.06.029 |
0.303 |
|
| 2012 |
SedláÄek O, Hrubý M, Studenovský M, VÄ›tviÄka D, Svoboda J, Kaňková D, Kovář J, Ulbrich K. Polymer conjugates of acridine-type anticancer drugs with pH-controlled activation. Bioorganic & Medicinal Chemistry. 20: 4056-63. PMID 22658535 DOI: 10.1016/j.bmc.2012.05.007 |
0.498 |
|
| 2012 |
Laga R, Carlisle R, Tangney M, Ulbrich K, Seymour LW. Polymer coatings for delivery of nucleic acid therapeutics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 537-53. PMID 22366547 DOI: 10.1016/j.jconrel.2012.02.013 |
0.35 |
|
| 2012 |
Hoffmann S, Vystrčilová L, Ulbrich K, Etrych T, Caysa H, Mueller T, Mäder K. Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: Synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging Biomacromolecules. 13: 652-663. PMID 22263698 DOI: 10.1021/bm2015027 |
0.524 |
|
| 2011 |
Kunjachan S, Błauż A, Möckel D, Theek B, Kiessling F, Etrych T, Ulbrich K, van Bloois L, Storm G, Bartosz G, Rychlik B, Lammers T. Overcoming cellular multidrug resistance using classical nanomedicine formulations. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 45: 421-8. PMID 21907796 DOI: 10.1016/j.ejps.2011.08.028 |
0.344 |
|
| 2011 |
Pechar M, Pola R, Laga R, Ulbrich K, Bednárová L, Maloň P, Sieglová I, Král V, Fábry M, Vaněk O. Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics. Biomacromolecules. 12: 3645-55. PMID 21863890 DOI: 10.1021/bm200897b |
0.326 |
|
| 2011 |
Etrych T, Kovář L, Strohalm J, Chytil P, Ríhová B, Ulbrich K. Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 154: 241-8. PMID 21699933 DOI: 10.1016/j.jconrel.2011.06.015 |
0.522 |
|
| 2011 |
Masek V, Anzenbacherová E, Etrych T, Strohalm J, Ulbrich K, Anzenbacher P. Interaction of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates with human liver microsomal cytochromes P450: comparison with free doxorubicin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1704-10. PMID 21642392 DOI: 10.1124/dmd.110.037986 |
0.405 |
|
| 2011 |
Hruby M, Filippov SK, Panek J, Novakova M, Mackova H, Kucka J, Ulbrich K. Thermoresponsive micelles for radionuclide delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 148: e60-2. PMID 21529629 DOI: 10.1016/j.jconrel.2010.07.024 |
0.368 |
|
| 2011 |
Sedlacek O, Hruby M, Studenovsky M, Kucka J, Vetvicka D, Kovar L, Rihova B, Ulbrich K. Ellipticine-aimed polymer-conjugated auger electron emitter: Multistage organelle targeting approach Bioconjugate Chemistry. 22: 1194-1201. PMID 21513348 DOI: 10.1021/bc200064v |
0.649 |
|
| 2011 |
Etrych T, Strohalm J, Chytil P, Černoch P, Starovoytova L, Pechar M, Ulbrich K. Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 42: 527-39. PMID 21392579 DOI: 10.1016/j.ejps.2011.03.001 |
0.539 |
|
| 2011 |
Kostka L, Koňák C, Šubr V, Špírková M, Addadi Y, Neeman M, Lammers T, Ulbrich K. Removable nanocoatings for siRNA polyplexes Bioconjugate Chemistry. 22: 169-179. PMID 21218805 DOI: 10.1021/Bc100197E |
0.359 |
|
| 2011 |
Lammers T, Subr V, Ulbrich K, Peschke P, Huber PE, Hennink WE, Storm G, Kiessling F. HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations. Nanomedicine (London, England). 5: 1501-23. PMID 21143030 DOI: 10.2217/nnm.10.130 |
0.414 |
|
| 2011 |
Hruby M, Filippov SK, Panek J, Novakova M, Mackova H, Kucka J, Vetvicka D, Ulbrich K. Polyoxazoline thermoresponsive micelles as radionuclide delivery systems. Macromolecular Bioscience. 10: 916-24. PMID 20491128 DOI: 10.1002/mabi.201000034 |
0.432 |
|
| 2010 |
Chytil P, Etrych T, Kříž J, Subr V, Ulbrich K. N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 41: 473-82. PMID 20696244 DOI: 10.1016/j.ejps.2010.08.003 |
0.535 |
|
| 2010 |
Talelli M, Iman M, Varkouhi AK, Rijcken CJ, Schiffelers RM, Etrych T, Ulbrich K, van Nostrum CF, Lammers T, Storm G, Hennink WE. Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin. Biomaterials. 31: 7797-804. PMID 20673684 DOI: 10.1016/j.biomaterials.2010.07.005 |
0.575 |
|
| 2010 |
Laga R, Konák C, Subr V, Ulbrich K, Suthiwangcharoen N, Niu Z, Wang Q. Chemical conjugation of cowpea mosaic viruses with reactive HPMA-based polymers. Journal of Biomaterials Science. Polymer Edition. 21: 1669-85. PMID 20537248 DOI: 10.1163/092050609X12547435571131 |
0.321 |
|
| 2010 |
Etrych T, Sírová M, Starovoytova L, Ríhová B, Ulbrich K. HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release. Molecular Pharmaceutics. 7: 1015-26. PMID 20518512 DOI: 10.1021/mp100119f |
0.593 |
|
| 2010 |
Sirova M, Mrkvan T, Etrych T, Chytil P, Rossmann P, Ibrahimova M, Kovar L, Ulbrich K, Rihova B. Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: Efficacy, safety, and immunomodulating activity in murine model Pharmaceutical Research. 27: 200-208. PMID 19894105 DOI: 10.1007/s11095-009-9999-7 |
0.418 |
|
| 2010 |
Pola R, Studenovský M, Pechar M, Ulbrich K, Hovorka O, Vetvicka D, Ríhová B. HPMA-copolymer conjugates targeted to tumor endothelium using synthetic oligopeptides. Journal of Drug Targeting. 17: 763-76. PMID 19863198 DOI: 10.3109/10611860903115282 |
0.377 |
|
| 2009 |
Ulbrich K, Subr V. Structural and chemical aspects of HPMA copolymers as drug carriers. Advanced Drug Delivery Reviews. 62: 150-66. PMID 19931329 DOI: 10.1016/j.addr.2009.10.007 |
0.515 |
|
| 2009 |
Vetvicka D, Hruby M, Hovorka O, Etrych T, Vetrik M, Kovar L, Kovar M, Ulbrich K, Rihova B. Biological evaluation of polymeric micelles with covalently bound doxorubicin Bioconjugate Chemistry. 20: 2090-2097. PMID 19835372 DOI: 10.1021/bc900212k |
0.331 |
|
| 2009 |
Etrych T, Strohalm J, Kovár L, Kabesová M, Ríhová B, Ulbrich K. HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 140: 18-26. PMID 19632282 DOI: 10.1016/j.jconrel.2009.07.011 |
0.468 |
|
| 2009 |
Hruby M, Konak C, Kucka J, Vetrik M, Filippov SK, Vetvicka D, Mackova H, Karlsson G, Edwards K, Rihova B, Ulbrich K. Thermoresponsive, hydrolytically degradable polymer micelles intended for radionuclide delivery. Macromolecular Bioscience. 9: 1016-27. PMID 19554646 DOI: 10.1002/mabi.200900083 |
0.436 |
|
| 2009 |
Krakovicová H, Etrych T, Ulbrich K. HPMA-based polymer conjugates with drug combination. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 37: 405-12. PMID 19491032 DOI: 10.1016/j.ejps.2009.03.011 |
0.571 |
|
| 2009 |
Lammers T, Subr V, Ulbrich K, Peschke P, Huber PE, Hennink WE, Storm G. Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers. Biomaterials. 30: 3466-75. PMID 19304320 DOI: 10.1016/j.biomaterials.2009.02.040 |
0.49 |
|
| 2009 |
Schneider GF, Subr V, Ulbrich K, Decher G. Multifunctional cytotoxic stealth nanoparticles. A model approach with potential for cancer therapy. Nano Letters. 9: 636-42. PMID 19170551 DOI: 10.1021/nl802990w |
0.393 |
|
| 2008 |
Konák C, Subr V, Kostka L, Stepánek P, Ulbrich K, Schlaad H. Coating of vesicles with hydrophilic reactive polymers. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 7092-8. PMID 18543996 DOI: 10.1021/La800119W |
0.557 |
|
| 2008 |
Etrych T, Chytil P, Mrkvan T, Sírová M, Ríhová B, Ulbrich K. Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting. Journal of Controlled Release : Official Journal of the Controlled Release Society. 132: 184-92. PMID 18534705 DOI: 10.1016/j.jconrel.2008.04.017 |
0.434 |
|
| 2007 |
Etrych T, Mrkvan T, Ríhová B, Ulbrich K. Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 122: 31-8. PMID 17631976 DOI: 10.1016/j.jconrel.2007.06.007 |
0.53 |
|
| 2007 |
Hruby M, Kucka J, Lebeda O, Mackova H, Babic M, Konak C, Studenovsky M, Sikora A, Kozempel J, Ulbrich K. New bioerodable thermoresponsive polymers for possible radiotherapeutic applications. Journal of Controlled Release : Official Journal of the Controlled Release Society. 119: 25-33. PMID 17379348 DOI: 10.1016/j.jconrel.2007.02.009 |
0.319 |
|
| 2007 |
Hovorka O, Etrych T, Subr V, Strohalm J, Ulbrich K, Ríhová B. HPMA based macromolecular therapeutics: internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition. Journal of Drug Targeting. 14: 391-403. PMID 17092839 DOI: 10.1080/10611860600833591 |
0.374 |
|
| 2006 |
Lammers T, Peschke P, Kühnlein R, Subr V, Ulbrich K, Debus J, Huber P, Hennink W, Storm G. Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society. 117: 333-41. PMID 17215057 DOI: 10.1016/j.jconrel.2006.10.032 |
0.404 |
|
| 2006 |
Lammers T, Peschke P, Kühnlein R, Subr V, Ulbrich K, Huber P, Hennink W, Storm G. Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems. Neoplasia (New York, N.Y.). 8: 788-95. PMID 17032495 DOI: 10.1593/neo.06436 |
0.345 |
|
| 2006 |
Chytil P, Etrych T, Konák C, Sírová M, Mrkvan T, Ríhová B, Ulbrich K. Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification. Journal of Controlled Release : Official Journal of the Controlled Release Society. 115: 26-36. PMID 16899320 DOI: 10.1016/j.jconrel.2006.06.028 |
0.544 |
|
| 2005 |
Lammers T, Kühnlein R, Kissel M, Subr V, Etrych T, Pola R, Pechar M, Ulbrich K, Storm G, Huber P, Peschke P. Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers Journal of Controlled Release. 110: 103-118. PMID 16274831 DOI: 10.1016/j.jconrel.2005.09.010 |
0.357 |
|
| 2005 |
Mrkvan T, Sirova M, Etrych T, Chytil P, Strohalm J, Plocova D, Ulbrich K, Rihova B. Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 110: 119-29. PMID 16269198 DOI: 10.1016/j.jconrel.2005.09.028 |
0.388 |
|
| 2005 |
Ulbrich K, Subr V. Polymeric anticancer drugs with pH-controlled activation. Advanced Drug Delivery Reviews. 56: 1023-50. PMID 15066758 DOI: 10.1016/j.addr.2003.10.040 |
0.519 |
|
| 2004 |
Hrubý M, Konák C, Ulbrich K. Polymeric micellar pH-sensitive drug delivery system for doxorubicin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 103: 137-48. PMID 15710507 DOI: 10.1016/j.jconrel.2004.11.017 |
0.505 |
|
| 2003 |
Ríhová B, Strohalm J, Kubácková K, Jelínková M, Rozprimová L, Sírová M, Plocová D, Mrkvan T, Kovár M, Pokorná J, Etrych T, Ulbrich K. Drug-HPMA-HuIg conjugates effective against human solid cancer. Advances in Experimental Medicine and Biology. 519: 125-43. PMID 12675212 DOI: 10.1007/0-306-47932-x_8 |
0.303 |
|
| 2002 |
Kissel M, Peschke P, Šubr V, Ulbrich K, Strunz AM, Kühnlein R, Debus J, Friedrich E. Detection and cellular localisation of the synthetic soluble macromolecular drug carrier pHPMA European Journal of Nuclear Medicine. 29: 1055-1062. PMID 12173020 DOI: 10.1007/s00259-002-0835-0 |
0.405 |
|
| 2002 |
St'astný M, Plocová D, Etrych T, Kovár M, Ulbrich K, Ríhová B. HPMA-hydrogels containing cytostatic drugs. Kinetics of the drug release and in vivo efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 81: 101-11. PMID 11992683 DOI: 10.1016/s0168-3659(02)00047-0 |
0.491 |
|
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