| Year |
Citation |
Score |
| 2020 |
Previtali V, Mihigo HB, Amet R, McElligott AM, Zisterer DM, Rozas I. Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives. Pharmaceuticals (Basel, Switzerland). 13. PMID 33371382 DOI: 10.3390/ph13120485 |
0.327 |
|
| 2020 |
McMullan M, Kelly B, Mihigo HB, Keogh AP, Rodriguez F, Brocos-Mosquera I, García-Bea A, Miranda-Azpiazu P, Callado LF, Rozas I. Di-aryl guanidinium derivatives: Towards improved α2-Adrenergic affinity and antagonist activity. European Journal of Medicinal Chemistry. 112947. PMID 33139112 DOI: 10.1016/j.ejmech.2020.112947 |
0.507 |
|
| 2020 |
Ahmed Al-Hadhrami N, Ladwig A, Rahman A, Rozas I, Paul G Malthouse J, Evans P. Synthesis of 2-guanidinyl pyridines and their trypsin inhibition and docking. Bioorganic & Medicinal Chemistry. 28: 115612. PMID 32690267 DOI: 10.1016/j.bmc.2020.115612 |
0.316 |
|
| 2018 |
Previtali V, Trujillo C, Amet R, Zisterer DM, Rozas I. Effect of isouronium/guanidinium substitution on the efficacy of a series of novel anti-cancer agents. Medchemcomm. 9: 735-743. PMID 30108964 DOI: 10.1039/c8md00089a |
0.307 |
|
| 2017 |
Flood A, Trujillo C, Sanchez-Sanz G, Kelly B, Muguruza C, Callado LF, Rozas I. Thiophene/thiazole-benzene replacement on guanidine derivatives targeting α2-Adrenoceptors. European Journal of Medicinal Chemistry. 138: 38-50. PMID 28644987 DOI: 10.1016/j.ejmech.2017.06.008 |
0.514 |
|
| 2015 |
Diez-Cecilia E, Carson R, Kelly B, van Schaeybroeck S, Murray JT, Rozas I. Probing a 3,4'-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway. Bioorganic & Medicinal Chemistry Letters. 25: 4287-92. PMID 26318998 DOI: 10.1016/J.Bmcl.2015.07.082 |
0.466 |
|
| 2015 |
Kelly B, McMullan M, Muguruza C, Ortega JE, Meana JJ, Callado LF, Rozas I. Correction to α₂-Adrenoceptor Antagonists: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of Pyridinoguanidine, Pyridino-2-aminoimidazoline and Their Derivatives. Journal of Medicinal Chemistry. 58: 3638. PMID 25868391 DOI: 10.1021/acs.jmedchem.5b00525 |
0.467 |
|
| 2015 |
Kelly B, McMullan M, Muguruza C, Ortega JE, Meana JJ, Callado LF, Rozas I. α2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives. Journal of Medicinal Chemistry. 58: 963-77. PMID 25490760 DOI: 10.1021/jm501635e |
0.528 |
|
| 2014 |
Diez-Cecilia E, Kelly B, Perez C, Zisterer DM, Nevin DK, Lloyd DG, Rozas I. Guanidinium-based derivatives: searching for new kinase inhibitors. European Journal of Medicinal Chemistry. 81: 427-41. PMID 24858546 DOI: 10.1016/j.ejmech.2014.05.025 |
0.476 |
|
| 2013 |
Aggarwal R, Bansal A, Rozas I, Kelly B, Kaushik P, Kaushik D. Synthesis, biological evaluation and molecular modeling study of 5-trifluoromethyl-Δ²-pyrazoline and isomeric 5/3-trifluoromethylpyrazole derivatives as anti-inflammatory agents. European Journal of Medicinal Chemistry. 70: 350-7. PMID 24177361 DOI: 10.1016/j.ejmech.2013.09.052 |
0.442 |
|
| 2013 |
Blanco F, Kelly B, Sánchez-Sanz G, Trujillo C, Alkorta I, Elguero J, Rozas I. Non-covalent interactions: complexes of guanidinium with DNA and RNA nucleobases. The Journal of Physical Chemistry. B. 117: 11608-16. PMID 23992551 DOI: 10.1021/jp407339v |
0.358 |
|
| 2011 |
Kelly B, O'Donovan DH, O'Brien J, McCabe T, Blanco F, Rozas I. Pyridin-2-yl guanidine derivatives: conformational control induced by intramolecular hydrogen-bonding interactions. The Journal of Organic Chemistry. 76: 9216-27. PMID 21977964 DOI: 10.1021/jo200954c |
0.397 |
|
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