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Jong K. Yun

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Neuroscience Biology, Pharmacology, Molecular Biology, Cell Biology
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"Jong Yun"
Mean distance: 35622
 
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Jacquelyn M. Francy grad student 2007 Penn State
Kelly Seaton grad student 2009 Penn State

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Publications

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Kale VP, Hengst JA, Sharma AK, et al. (2023) Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases. Pharmaceuticals (Basel, Switzerland). 16
Hengst JA, Nduwumwami AJ, Yun JK. (2022) Regulatory Role of Sphingosine-1-Phosphate and C16:0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation. Cancers. 14
Hengst JA, Nduwumwami AJ, Raup-Konsavage WM, et al. (2021) Inhibition of Sphingosine Kinase Activity Enhances Immunogenic Cell Surface Exposure of Calreticulin Induced by the Synthetic Cannabinoid 5-epi-CP-55,940. Cannabis and Cannabinoid Research
Nduwumwami AJ, Hengst JA, Yun JK. (2021) Sphingosine kinase inhibition enhances dimerization of calreticulin at the cell surface in mitoxantrone-induced immunogenic cell death. The Journal of Pharmacology and Experimental Therapeutics
Hengst JA, Dick TE, Smith CD, et al. (2020) Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA). Cancer Biology & Therapy. 1-12
Hengst JA, Hegde S, Paulson RF, et al. (2020) Development of SKI-349, a Dual-Targeted Inhibitor of Sphingosine Kinase and Microtubule Polymerization. Bioorganic & Medicinal Chemistry Letters. 127453
Hengst JA, Dick TE, Sharma A, et al. (2017) SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models. Cancer Translational Medicine. 3: 109-121
Tan SF, Liu X, Fox TE, et al. (2016) Acid ceramidase is upregulated in AML and represents a novel therapeutic target. Oncotarget
Young MM, Takahashi Y, Fox TE, et al. (2016) Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking. Cell Reports. 17: 1532-1545
Desai DH, Kale VP, Hengst JA, et al. (2016) Abstract 4805: In vitro characterization of novel inhibitors of ROCK and MRCK kinases as anticancer agents Cancer Research. 76: 4805-4805
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