Rosalyn B. Irby
Affiliations: | Pennsylvania State University, State College, PA, United States |
Area:
Molecular Biology, Biochemistry, OncologyWebsite:
https://profiles.psu.edu/profiles/display/111861Google:
"Rosalyn Bryson Irby"Bio:
https://www.researchgate.net/profile/Rosalyn_Irby
http://www.jbc.org/content/269/39/23981.short
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Parents
Sign in to add mentor| Winston Lee Adair | grad student | 1994 | University of South Florida | |
| (Elucidation of the biosynthetic pathway of molybdopterin in the yeast pichia canadensis.) | ||||
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Publications
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| Nguyen JQ, Irby RB. (2016) TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells. Cancer Biology & Therapy. 0 |
| Nguyen J, Irby R. (2015) Abstract 2039: Trim21: A novel regulator of Par-4 and oncogenic signaling Cancer Research. 75: 2039-2039 |
| Allen JE, Gallant JN, Dicker DT, et al. (2013) The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer. Plos One. 8: e59380 |
| Irby RB, Kline CL. (2013) Par-4 as a potential target for cancer therapy. Expert Opinion On Therapeutic Targets. 17: 77-87 |
| Allen JE, Gallant J, Dicker DT, et al. (2013) Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer Plos One. 8 |
| Karelia D, Pandey MK, Irby R, et al. (2013) Abstract 3439: Suppression of pancreatic cancer cell growth by NISC-6 through activation of Par-4 and death receptor 5. Cancer Research. 73: 3439-3439 |
| Krishnegowda G, Prakasha Gowda AS, Tagaram HR, et al. (2011) Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorganic & Medicinal Chemistry. 19: 6006-14 |
| Kline CL, Irby RB. (2011) The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. Apoptosis : An International Journal On Programmed Cell Death. 16: 1285-94 |
| Sharma AK, Kline CL, Berg A, et al. (2011) The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4474-83 |
| Contract D, Mackley H, Irby RB. (2011) Par-4 Sensitizes Human Colon Cancer Cells to Chemoradiotherapy Journal of Cancer Therapy. 2: 542-547 |