| Year |
Citation |
Score |
| 2016 |
Nguyen JQ, Irby RB. TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells. Cancer Biology & Therapy. 0. PMID 27830973 DOI: 10.1080/15384047.2016.1252880 |
0.546 |
|
| 2015 |
Nguyen J, Irby R. Abstract 2039: Trim21: A novel regulator of Par-4 and oncogenic signaling Cancer Research. 75: 2039-2039. DOI: 10.1158/1538-7445.Am2015-2039 |
0.463 |
|
| 2013 |
Allen JE, Gallant JN, Dicker DT, Amin S, Irby RB, Sharma AK, El-Deiry WS. The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer. Plos One. 8: e59380. PMID 23555026 DOI: 10.1371/Journal.Pone.0059380 |
0.537 |
|
| 2013 |
Irby RB, Kline CL. Par-4 as a potential target for cancer therapy. Expert Opinion On Therapeutic Targets. 17: 77-87. PMID 23062118 DOI: 10.1517/14728222.2013.731047 |
0.708 |
|
| 2013 |
Allen JE, Gallant J, Dicker DT, Amin S, Irby RB, Sharma AK, El-Deiry WS. Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer Plos One. 8. DOI: 10.1371/Annotation/Aaa12360-0C90-42C3-Bc43-D00022B68B81 |
0.351 |
|
| 2013 |
Karelia D, Pandey MK, Irby R, Amin S, Sharma AK. Abstract 3439: Suppression of pancreatic cancer cell growth by NISC-6 through activation of Par-4 and death receptor 5. Cancer Research. 73: 3439-3439. DOI: 10.1158/1538-7445.Am2013-3439 |
0.543 |
|
| 2011 |
Krishnegowda G, Prakasha Gowda AS, Tagaram HR, Carroll KF, Irby RB, Sharma AK, Amin S. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorganic & Medicinal Chemistry. 19: 6006-14. PMID 21920762 DOI: 10.1016/J.Bmc.2011.08.044 |
0.445 |
|
| 2011 |
Kline CL, Irby RB. The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. Apoptosis : An International Journal On Programmed Cell Death. 16: 1285-94. PMID 21910008 DOI: 10.1007/S10495-011-0648-3 |
0.733 |
|
| 2011 |
Sharma AK, Kline CL, Berg A, Amin S, Irby RB. The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4474-83. PMID 21555373 DOI: 10.1158/1078-0432.Ccr-10-2370 |
0.719 |
|
| 2011 |
Contract D, Mackley H, Irby RB. Par-4 Sensitizes Human Colon Cancer Cells to Chemoradiotherapy Journal of Cancer Therapy. 2: 542-547. DOI: 10.4236/Jct.2011.24074 |
0.505 |
|
| 2011 |
Desai DH, Irby R, Aliaga C, Amin SG. Abstract 4628: PBISe, an iNOS/Akt inhibitor for colon cancer chemoprevention Cancer Research. 71: 4628-4628. DOI: 10.1158/1538-7445.Am2011-4628 |
0.495 |
|
| 2011 |
Fino KK, Irby RB, Smith JP. Abstract 2891: Gastrin signaling and Par-4 in pancreatic cancer Cancer Research. 71: 2891-2891. DOI: 10.1158/1538-7445.Am2011-2891 |
0.51 |
|
| 2011 |
House CD, Samaan M, Irby RB, Lee NH. Abstract 1418: Voltage-gated Na+ channel activation leads to increased invasion potential through persistent MAPK signaling involving PKA, Src, and Rap1 Cancer Research. 71: 1418-1418. DOI: 10.1158/1538-7445.Am2011-1418 |
0.486 |
|
| 2010 |
Irby RB. Epidermal growth factor receptor revisited: prognostic marker or target for therapy? Cancer Biology & Therapy. 10: 422-4. PMID 20724833 DOI: 10.4161/Cbt.10.5.13194 |
0.357 |
|
| 2010 |
House CD, Vaske CJ, Schwartz AM, Obias V, Frank B, Luu T, Sarvazyan N, Irby R, Strausberg RL, Hales TG, Stuart JM, Lee NH. Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion. Cancer Research. 70: 6957-67. PMID 20651255 DOI: 10.1158/0008-5472.Can-10-1169 |
0.472 |
|
| 2010 |
Wang BD, Kline CL, Pastor DM, Olson TL, Frank B, Luu T, Sharma AK, Robertson G, Weirauch MT, Patierno SR, Stuart JM, Irby RB, Lee NH. Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network. Molecular Cancer. 9: 98. PMID 20433755 DOI: 10.1186/1476-4598-9-98 |
0.709 |
|
| 2010 |
Pastor DM, Poritz LS, Olson TL, Kline CL, Harris LR, Koltun WA, Chinchilli VM, Irby RB. Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines. International Journal of Clinical and Experimental Medicine. 3: 69-83. PMID 20369042 |
0.693 |
|
| 2010 |
Pastor DM, Irby RB, Poritz LS. Tumor necrosis factor alpha induces p53 up-regulated modulator of apoptosis expression in colorectal cancer cell lines. Diseases of the Colon and Rectum. 53: 257-63. PMID 20173470 DOI: 10.1007/Dcr.0B013E3181C522C7 |
0.388 |
|
| 2010 |
Yang J, Liu X, Nyland SB, Zhang R, Ryland LK, Broeg K, Baab KT, Jarbadan NR, Irby R, Loughran TP. Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway. Blood. 115: 51-60. PMID 19880494 DOI: 10.1182/Blood-2009-06-223719 |
0.356 |
|
| 2010 |
Irby RB, Kline CL, Sharma AK. Abstract 1209: Par-4 as therapy for colon cancer Cancer Research. 70: 1209-1209. DOI: 10.1158/1538-7445.Am10-1209 |
0.735 |
|
| 2009 |
Kline CL, Shanmugavelandy SS, Kester M, Irby RB. Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU. Cancer Biology & Therapy. 8: 1831-7. PMID 19729995 DOI: 10.4161/Cbt.8.19.9592 |
0.75 |
|
| 2009 |
Kline CL, Olson TL, Irby RB. Src activity alters alpha3 integrin expression in colon tumor cells. Clinical & Experimental Metastasis. 26: 77-87. PMID 18839319 DOI: 10.1007/S10585-008-9215-X |
0.697 |
|
| 2008 |
Shah MV, Zhang R, Irby R, Kothapalli R, Liu X, Arrington T, Frank B, Lee NH, Loughran TP. Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes. Blood. 112: 770-81. PMID 18477771 DOI: 10.1182/Blood-2007-11-121871 |
0.366 |
|
| 2008 |
Kline CL, Jackson R, Engelman R, Pledger WJ, Yeatman TJ, Irby RB. Src kinase induces tumor formation in the c-SRC C57BL/6 mouse. International Journal of Cancer. Journal International Du Cancer. 122: 2665-73. PMID 18351644 DOI: 10.1002/Ijc.23445 |
0.718 |
|
| 2005 |
Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Role of Stat3 in regulating p53 expression and function. Molecular and Cellular Biology. 25: 7432-40. PMID 16107692 DOI: 10.1128/Mcb.25.17.7432-7440.2005 |
0.425 |
|
| 2005 |
Cook AC, Tuck AB, McCarthy S, Turner JG, Irby RB, Bloom GC, Yeatman TJ, Chambers AF. Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression. Molecular Carcinogenesis. 43: 225-36. PMID 15864800 DOI: 10.1002/Mc.20105 |
0.484 |
|
| 2005 |
Irby RB, Malek RL, Bloom G, Tsai J, Letwin N, Frank BC, Verratti K, Yeatman TJ, Lee NH. Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype. Cancer Research. 65: 1814-21. PMID 15753379 DOI: 10.1158/0008-5472.Can-04-3609 |
0.392 |
|
| 2004 |
Irby RB, McCarthy SM, Yeatman TJ. Osteopontin regulates multiple functions contributing to human colon cancer development and progression Clinical and Experimental Metastasis. 21: 515-523. PMID 15679049 DOI: 10.1007/S10585-004-2873-4 |
0.493 |
|
| 2003 |
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as colon cancer tumor progression marker. Comptes Rendus Biologies. 326: 1041-3. PMID 14744111 DOI: 10.1016/J.Crvi.2003.09.007 |
0.455 |
|
| 2003 |
Chen T, Yang I, Irby R, Shain KH, Wang HG, Quackenbush J, Coppola D, Cheng JQ, Yeatman TJ. Regulation of caspase expression and apoptosis by adenomatous polyposis coli Cancer Research. 63: 4368-4374. PMID 12907606 |
0.321 |
|
| 2003 |
Lopez D, Irby RB, McLean MP. Peroxisome proliferator-activated receptor alpha induces rat sterol carrier protein x promoter activity through two peroxisome proliferator-response elements. Molecular and Cellular Endocrinology. 205: 169-84. PMID 12890579 DOI: 10.1016/S0303-7207(02)00300-3 |
0.316 |
|
| 2002 |
Malek RL, Irby RB, Guo QM, Lee K, Wong S, He M, Tsai J, Frank B, Liu ET, Quackenbush J, Jove R, Yeatman TJ, Lee NH. Identification of Src transformation fingerprint in human colon cancer. Oncogene. 21: 7256-65. PMID 12370817 DOI: 10.1038/Sj.Onc.1205900 |
0.452 |
|
| 2002 |
Irby RB, Yeatman TJ. Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells. Cancer Research. 62: 2669-74. PMID 11980666 |
0.402 |
|
| 2002 |
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. Journal of the National Cancer Institute. 94: 513-21. PMID 11929952 DOI: 10.1093/Jnci/94.7.513 |
0.422 |
|
| 2001 |
Teng S, Sun J, Irby R, Hamilton AD, Sebti S, Yeatman TJ. v-Src transformation is mediated through farnesylated proteins. The Journal of Surgical Research. 99: 343-6. PMID 11469908 DOI: 10.1006/Jsre.2001.6184 |
0.329 |
|
| 2001 |
Bowman T, Broome MA, Sinibaldi D, Wharton W, Pledger WJ, Sedivy JM, Irby R, Yeatman T, Courtneidge SA, Jove R. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 7319-24. PMID 11404481 DOI: 10.1073/Pnas.131568898 |
0.365 |
|
| 2000 |
Irby RB, Yeatman TJ. Role of Src expression and activation in human cancer Oncogene. 19: 5636-5642. PMID 11114744 DOI: 10.1038/Sj.Onc.1203912 |
0.488 |
|
| 1999 |
Irby RB, Mao W, Coppola D, Kang J, Loubeau JM, Trudeau W, Karl R, Fujita DJ, Jove R, Yeatman TJ. Activating SRC mutation in a subset of advanced human colon cancers Nature Genetics. 21: 187-190. PMID 9988270 DOI: 10.1038/5971 |
0.41 |
|
| 1997 |
Mao W, Irby R, Coppola D, Fu L, Wloch M, Turner J, Yu H, Garcia R, Jove R, Yeatman TJ. Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential Oncogene. 15: 3083-3090. PMID 9444956 DOI: 10.1038/Sj.Onc.1201496 |
0.444 |
|
| 1994 |
Irby R, Adair WL. Enzymatic preparation of [2,4,5,6,8-14C, 5'-3H]guanosine for use in biosynthetic studies of pterinoid and flavin compounds. Analytical Biochemistry. 218: 413-6. PMID 8074301 DOI: 10.1006/Abio.1994.1200 |
0.626 |
|
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