Francis Ali-Osman
Affiliations: | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Francis Ali-Osman"Children
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Publications
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| Madala HR, Punganuru SR, Ali-Osman F, et al. (2018) Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts. Oncotarget. 9: 3459-3482 |
| Gabr M, Marcus S, Madala HR, et al. (2017) Abstract 4053: Disulfiram-copper combination induces cell death time- and schedule-dependently in glioblastoma (GBM) and medulloblastoma cell lines, and enhances temozolomide sensitivity of methylator+ve GBM cellsin vitroandin vivo Cancer Research. 77: 4053-4053 |
| Madala HR, Punganuru SR, Ali-Osman F, et al. (2017) Abstract 2044: Development of stable and brain-penetrating disulfiram nanoparticles, characterization and efficacy in glioma cell culture and xenograft models Cancer Research. 77: 2044-2044 |
| Paranjpe A, Bailey NI, Konduri S, et al. (2016) New insights into estrogenic regulation of O(6)-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O(6)-benzylguanine indicates fresh avenues for therapy. Journal of Biomedical Research. 30: 393-410 |
| Lai RK, Zhou R, Amirian ES, et al. (2016) Abstract 3446: Aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of glioma: Results from the Glioma International Case Control Study Cancer Research. 76: 3446-3446 |
| Okamura T, Antoun G, Keir ST, et al. (2015) Phosphorylation of GSTP1 by EGFR Promotes Formation of the Inhibitory GSTP1-JNK Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells. The Journal of Biological Chemistry |
| Brown KE, Chagoya G, Kwatra SG, et al. (2015) Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development. Journal of Neurochemistry. 133: 730-8 |
| Lidsky M, Antoun G, Speicher P, et al. (2014) Mitogen-activated protein kinase (MAPK) hyperactivation and enhanced NRAS expression drive acquired vemurafenib resistance in V600E BRAF melanoma cells. The Journal of Biological Chemistry. 289: 27714-26 |
| Paranjpe A, Zhang R, Ali-Osman F, et al. (2014) Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage. Carcinogenesis. 35: 692-702 |
| Yang W, Wang L, Roehn G, et al. (2013) Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival. Cancer Science. 104: 70-7 |