Hui-Wen Lo, Ph.D.
Affiliations: | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Hui-Wen Lo"Parents
Sign in to add mentor| Francis Ali-Osman | grad student | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
| (Signaling pathways in the transcriptional and post-translational regulation of the human glutathione S -transferase P1 gene.) | ||||
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Publications
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| Song Q, Ruiz J, Xing F, et al. (2023) Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment. Communications Biology. 6: 760 |
| Arrigo A, Regua AT, Najjar MK, et al. (2023) Tumor Suppressor Candidate 2 (TUSC2): Discovery, Functions, and Cancer Therapy. Cancers. 15 |
| Doheny D, Manore S, Sirkisoon SR, et al. (2022) An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1. Cancers. 14 |
| Wong GL, Manore SG, Doheny DL, et al. (2022) STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges. Seminars in Cancer Biology |
| Regua AT, Najjar M, Lo HW. (2022) RET signaling pathway and RET inhibitors in human cancer. Frontiers in Oncology. 12: 932353 |
| Regua AT, Aguayo NR, Jalboush SA, et al. (2021) TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. Cancers. 13 |
| Sirkisoon SR, Carpenter RL, Rimkus T, et al. (2021) Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment. Oncogene |
| Wang G, Wang J, Chang A, et al. (2020) Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2. Oncogene |
| Doheny D, Manore SG, Wong GL, et al. (2020) Hedgehog Signaling and Truncated GLI1 in Cancer. Cells. 9 |
| Doheny D, Sirkisoon S, Carpenter RL, et al. (2020) Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis. Oncogene |