Luke Pike

Affiliations: 
2007-2010 University of Oxford, Oxford, United Kingdom 
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"Luke Pike"
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Publications

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Pike LR, Singleton DC, Buffa F, et al. (2013) Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. The Biochemical Journal. 449: 389-400
Pike LR, Phadwal K, Simon AK, et al. (2012) ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia. Molecular Biology Reports. 39: 10811-22
Phadwal K, Alegre-Abarrategui J, Watson AS, et al. (2012) A novel method for autophagy detection in primary cells: Impaired levels of macroautophagy in immunosenescent T cells Autophagy. 8: 677-689
Rzymski T, Petry A, Kračun D, et al. (2012) The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress. Oncogene. 31: 3621-34
Nanka O, Krejci E, Pesevski Z, et al. (2012) Poster session 3 Cardiovascular Research. 93: S92-S127
Yang J, Jubb AM, Pike L, et al. (2010) The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Research. 70: 6456-66
Rzymski T, Milani M, Pike L, et al. (2010) Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene. 29: 4424-35
Milani M, Rzymski T, Mellor HR, et al. (2009) The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Research. 69: 4415-23
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