Year |
Citation |
Score |
2022 |
Hecht ES, Mehta S, Wecksler AT, Aguilar B, Swanson N, Phung W, Dubey Kelsoe A, Benner WH, Tesar D, Kelley RF, Sandoval W, Sreedhara A. Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms. Mabs. 14: 2135183. PMID 36284469 DOI: 10.1080/19420862.2022.2135183 |
0.307 |
|
2019 |
Chung S, Nguyen V, Lin YL, Lafrance-Vanasse J, Scales SJ, Lin K, Deng R, Williams K, Sperinde G, Li JJ, Zheng K, Sukumaran S, Tesar D, Ernst JA, Fischer S, et al. An in vitro FcRn-dependent transcytosis assay as a screening tool for predictive assessment of non-specific clearance of antibody therapeutics in humans. Mabs. PMID 30982394 DOI: 10.1080/19420862.2019.1605270 |
0.453 |
|
2017 |
Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, Campagne MVL, et al. Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye. Mabs. 0. PMID 28854082 DOI: 10.1080/19420862.2017.1372078 |
0.37 |
|
2015 |
Bumbaca Yadav D, Sharma VK, Boswell CA, Hotzel I, Tesar D, Shang Y, Ying Y, Fischer SK, Grogan JL, Chiang EY, Urban K, Ulufatu S, Khawli LA, Prabhu S, Joseph S, et al. Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics. The Journal of Biological Chemistry. PMID 26491012 DOI: 10.1074/Jbc.M115.692434 |
0.372 |
|
2015 |
Shang Y, Tesar D, Hötzel I. Modular protein expression by RNA trans-splicing enables flexible expression of antibody formats in mammalian cells from a dual-host phage display vector. Protein Engineering, Design & Selection : Peds. PMID 25855659 DOI: 10.1093/Protein/Gzv018 |
0.385 |
|
2014 |
Li B, Tesar D, Boswell CA, Cahaya HS, Wong A, Zhang J, Meng YG, Eigenbrot C, Pantua H, Diao J, Kapadia SB, Deng R, Kelley RF. Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge. Mabs. 6: 1255-64. PMID 25517310 DOI: 10.4161/Mabs.29809 |
0.451 |
|
2014 |
Yip V, Palma E, Tesar DB, Mundo EE, Bumbaca D, Torres EK, Reyes NA, Shen BQ, Fielder PJ, Prabhu S, Khawli LA, Boswell CA. Quantitative cumulative biodistribution of antibodies in mice: effect of modulating binding affinity to the neonatal Fc receptor. Mabs. 6: 689-96. PMID 24572100 DOI: 10.4161/Mabs.28254 |
0.477 |
|
2013 |
Tesar D, Hötzel I. A dual host vector for Fab phage display and expression of native IgG in mammalian cells. Protein Engineering, Design & Selection : Peds. 26: 655-62. PMID 24065833 DOI: 10.1093/Protein/Gzt050 |
0.389 |
|
2012 |
Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, et al. Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration. Mabs. 4: 243-55. PMID 22453096 DOI: 10.4161/Mabs.4.2.19387 |
0.395 |
|
2011 |
Bai Y, Ye L, Tesar DB, Song H, Zhao D, Björkman PJ, Roopenian DC, Zhu X. Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport. Proceedings of the National Academy of Sciences of the United States of America. 108: 18406-11. PMID 22042859 DOI: 10.1073/Pnas.1115348108 |
0.552 |
|
2010 |
Boswell CA, Tesar DB, Mukhyala K, Theil FP, Fielder PJ, Khawli LA. Effects of charge on antibody tissue distribution and pharmacokinetics. Bioconjugate Chemistry. 21: 2153-63. PMID 21053952 DOI: 10.1021/Bc100261D |
0.412 |
|
2010 |
Khawli LA, Goswami S, Hutchinson R, Kwong ZW, Yang J, Wang X, Yao Z, Sreedhara A, Cano T, Tesar D, Nijem I, Allison DE, Wong PY, Kao YH, Quan C, et al. Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats. Mabs. 2: 613-24. PMID 20818176 DOI: 10.4161/Mabs.2.6.13333 |
0.358 |
|
2010 |
Jerdeva GV, Tesar DB, Huey-Tubman KE, Ladinsky MS, Fraser SE, Bjorkman PJ. Comparison of FcRn- and pIgR-mediated transport in MDCK cells by fluorescence confocal microscopy. Traffic (Copenhagen, Denmark). 11: 1205-20. PMID 20525015 DOI: 10.1111/J.1600-0854.2010.01083.X |
0.578 |
|
2010 |
Tesar DB, Björkman PJ. An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G Current Opinion in Structural Biology. 20: 226-233. PMID 20171874 DOI: 10.1016/J.Sbi.2010.01.010 |
0.588 |
|
2008 |
Tesar DB, Cheung EJ, Bjorkman PJ. The chicken yolk sac IgY receptor, a mammalian mannose receptor family member, transcytoses IgY across polarized epithelial cells. Molecular Biology of the Cell. 19: 1587-93. PMID 18256279 DOI: 10.1091/Mbc.E07-09-0972 |
0.595 |
|
2007 |
He W, Kivork C, Machinani S, Morphew MK, Gail AM, Tesar DB, Tiangco NE, McIntosh JR, Bjorkman PJ. A freeze substitution fixation-based gold enlarging technique for EM studies of endocytosed Nanogold-labeled molecules. Journal of Structural Biology. 160: 103-13. PMID 17723309 DOI: 10.1016/J.Jsb.2007.07.004 |
0.541 |
|
2006 |
Tesar DB, Tiangco NE, Bjorkman PJ. Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor. Traffic (Copenhagen, Denmark). 7: 1127-42. PMID 17004319 DOI: 10.1111/J.1600-0854.2006.00457.X |
0.617 |
|
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