Devin B. Tesar, Ph.D. - Publications

Affiliations: 
Biology California Institute of Technology, Pasadena, CA 
Area:
cell surface recognition

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hecht ES, Mehta S, Wecksler AT, Aguilar B, Swanson N, Phung W, Dubey Kelsoe A, Benner WH, Tesar D, Kelley RF, Sandoval W, Sreedhara A. Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms. Mabs. 14: 2135183. PMID 36284469 DOI: 10.1080/19420862.2022.2135183  0.307
2019 Chung S, Nguyen V, Lin YL, Lafrance-Vanasse J, Scales SJ, Lin K, Deng R, Williams K, Sperinde G, Li JJ, Zheng K, Sukumaran S, Tesar D, Ernst JA, Fischer S, et al. An in vitro FcRn-dependent transcytosis assay as a screening tool for predictive assessment of non-specific clearance of antibody therapeutics in humans. Mabs. PMID 30982394 DOI: 10.1080/19420862.2019.1605270  0.453
2017 Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, Campagne MVL, et al. Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye. Mabs. 0. PMID 28854082 DOI: 10.1080/19420862.2017.1372078  0.37
2015 Bumbaca Yadav D, Sharma VK, Boswell CA, Hotzel I, Tesar D, Shang Y, Ying Y, Fischer SK, Grogan JL, Chiang EY, Urban K, Ulufatu S, Khawli LA, Prabhu S, Joseph S, et al. Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics. The Journal of Biological Chemistry. PMID 26491012 DOI: 10.1074/Jbc.M115.692434  0.372
2015 Shang Y, Tesar D, Hötzel I. Modular protein expression by RNA trans-splicing enables flexible expression of antibody formats in mammalian cells from a dual-host phage display vector. Protein Engineering, Design & Selection : Peds. PMID 25855659 DOI: 10.1093/Protein/Gzv018  0.385
2014 Li B, Tesar D, Boswell CA, Cahaya HS, Wong A, Zhang J, Meng YG, Eigenbrot C, Pantua H, Diao J, Kapadia SB, Deng R, Kelley RF. Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge. Mabs. 6: 1255-64. PMID 25517310 DOI: 10.4161/Mabs.29809  0.451
2014 Yip V, Palma E, Tesar DB, Mundo EE, Bumbaca D, Torres EK, Reyes NA, Shen BQ, Fielder PJ, Prabhu S, Khawli LA, Boswell CA. Quantitative cumulative biodistribution of antibodies in mice: effect of modulating binding affinity to the neonatal Fc receptor. Mabs. 6: 689-96. PMID 24572100 DOI: 10.4161/Mabs.28254  0.477
2013 Tesar D, Hötzel I. A dual host vector for Fab phage display and expression of native IgG in mammalian cells. Protein Engineering, Design & Selection : Peds. 26: 655-62. PMID 24065833 DOI: 10.1093/Protein/Gzt050  0.389
2012 Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, et al. Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration. Mabs. 4: 243-55. PMID 22453096 DOI: 10.4161/Mabs.4.2.19387  0.395
2011 Bai Y, Ye L, Tesar DB, Song H, Zhao D, Björkman PJ, Roopenian DC, Zhu X. Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport. Proceedings of the National Academy of Sciences of the United States of America. 108: 18406-11. PMID 22042859 DOI: 10.1073/Pnas.1115348108  0.552
2010 Boswell CA, Tesar DB, Mukhyala K, Theil FP, Fielder PJ, Khawli LA. Effects of charge on antibody tissue distribution and pharmacokinetics. Bioconjugate Chemistry. 21: 2153-63. PMID 21053952 DOI: 10.1021/Bc100261D  0.412
2010 Khawli LA, Goswami S, Hutchinson R, Kwong ZW, Yang J, Wang X, Yao Z, Sreedhara A, Cano T, Tesar D, Nijem I, Allison DE, Wong PY, Kao YH, Quan C, et al. Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats. Mabs. 2: 613-24. PMID 20818176 DOI: 10.4161/Mabs.2.6.13333  0.358
2010 Jerdeva GV, Tesar DB, Huey-Tubman KE, Ladinsky MS, Fraser SE, Bjorkman PJ. Comparison of FcRn- and pIgR-mediated transport in MDCK cells by fluorescence confocal microscopy. Traffic (Copenhagen, Denmark). 11: 1205-20. PMID 20525015 DOI: 10.1111/J.1600-0854.2010.01083.X  0.578
2010 Tesar DB, Björkman PJ. An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G Current Opinion in Structural Biology. 20: 226-233. PMID 20171874 DOI: 10.1016/J.Sbi.2010.01.010  0.588
2008 Tesar DB, Cheung EJ, Bjorkman PJ. The chicken yolk sac IgY receptor, a mammalian mannose receptor family member, transcytoses IgY across polarized epithelial cells. Molecular Biology of the Cell. 19: 1587-93. PMID 18256279 DOI: 10.1091/Mbc.E07-09-0972  0.595
2007 He W, Kivork C, Machinani S, Morphew MK, Gail AM, Tesar DB, Tiangco NE, McIntosh JR, Bjorkman PJ. A freeze substitution fixation-based gold enlarging technique for EM studies of endocytosed Nanogold-labeled molecules. Journal of Structural Biology. 160: 103-13. PMID 17723309 DOI: 10.1016/J.Jsb.2007.07.004  0.541
2006 Tesar DB, Tiangco NE, Bjorkman PJ. Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor. Traffic (Copenhagen, Denmark). 7: 1127-42. PMID 17004319 DOI: 10.1111/J.1600-0854.2006.00457.X  0.617
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