| Year |
Citation |
Score |
| 2024 |
Kraft AE, Bork NI, Subramanian H, Pavlaki N, Failla AV, Zobiak B, Conti M, Nikolaev VO. Phosphodiesterases 4B and 4D Differentially Regulate cAMP Signaling in Calcium Handling Microdomains of Mouse Hearts. Cells. 13. PMID 38534320 DOI: 10.3390/cells13060476 |
0.367 |
|
| 2023 |
Lai P, Hille SS, Subramanian H, Weigman R, Roser P, Müller OJ, Nikolaev VO, De Jong KA. Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes. Cardiovascular Research. PMID 38099489 DOI: 10.1093/cvr/cvad178 |
0.305 |
|
| 2023 |
Bork NI, Subramanian H, Kurelic R, Nikolaev VO, Rybalkin SD. Role of Phosphodiesterase 1 in the Regulation of Real-Time cGMP Levels and Contractility in Adult Mouse Cardiomyocytes. Cells. 12. PMID 38067187 DOI: 10.3390/cells12232759 |
0.33 |
|
| 2023 |
Kostenis E, Gomeza J, Miess-Tanneberg E, Blum NK, Benkel T, Chevigné A, Hoffmann C, Kolb P, Nikolaev V, Waldhoer M, Szpakowska M, Inoue A, Schulz S. Reply to: How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7867. PMID 38036502 DOI: 10.1038/s41467-023-42849-4 |
0.566 |
|
| 2023 |
Lezoualc'h F, Nikolaev VO. Receptor-Specific Inside-Out cAMP Signaling Regulates Cardiomyocyte Fate. Circulation Research. 133: 924-926. PMID 37943945 DOI: 10.1161/CIRCRESAHA.123.323754 |
0.339 |
|
| 2023 |
Kwan Z, Nadappuram BP, Leung MM, Kondrashov A, Mohagaonkar S, Li A, Amaradasa KS, Chen J, Rothery S, Kibreab I, Fu J, Sanchez-Alonso JL, Mansfield CA, Subramanian H, Wright PT, ... ... Nikolaev VO, et al. Microtubule-Mediated Regulation of βAR Translation and Function in Failing Hearts. Circulation Research. PMID 37869877 DOI: 10.1161/CIRCRESAHA.123.323174 |
0.823 |
|
| 2023 |
De Jong KA, Ehret S, Heeren J, Nikolaev VO. Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes. Cell Reports. 42: 112433. PMID 37099421 DOI: 10.1016/j.celrep.2023.112433 |
0.342 |
|
| 2022 |
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-Tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, ... ... Nikolaev V, et al. How Carvedilol activates β-adrenoceptors. Nature Communications. 13: 7109. PMID 36402762 DOI: 10.1038/s41467-022-34765-w |
0.757 |
|
| 2022 |
Faleeva M, Diakonov I, Srivastava P, Ramuz M, Calamera G, Andressen KW, Bork N, Tsansizi L, Cosson MV, Bernardo AS, Nikolaev V, Gorelik J. Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture. Cells. 11. PMID 36291124 DOI: 10.3390/cells11203257 |
0.72 |
|
| 2021 |
Beneke K, Pavlidou NG, Schäfer A, Nikolaev VO, Molina CE. GPCR signaling is highly compartmentalized in human cardiomyocytes and severely remodeled in atrial fibrillation. The Journal of General Physiology. 154. PMID 34807977 DOI: 10.1085/jgp.2021ecc49 |
0.336 |
|
| 2021 |
Berisha F, Götz K, Wegener JW, Brandenburg S, Subramanian H, Molina CE, Rueffer A, Petersen J, Bernhardt A, Girdauskas E, Jungen C, Pape U, Kraft AE, Warnke S, Lindner D, ... ... Nikolaev VO, et al. cAMP Imaging at Ryanodine Receptors Reveals β2-Adrenoceptor Driven Arrhythmias. Circulation Research. PMID 33902292 DOI: 10.1161/CIRCRESAHA.120.318234 |
0.395 |
|
| 2021 |
Pavlaki N, De Jong KA, Geertz B, Nikolaev VO, Froese A. Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains. Cells. 10. PMID 33802377 DOI: 10.3390/cells10030535 |
0.35 |
|
| 2020 |
Mensching L, Rading S, Nikolaev V, Karsak M. Monitoring Cannabinoid CB2 -Receptor Mediated cAMP Dynamics by FRET-Based Live Cell Imaging. International Journal of Molecular Sciences. 21. PMID 33114208 DOI: 10.3390/ijms21217880 |
0.363 |
|
| 2020 |
Špiranec Spes K, Chen W, Krebes L, Völker K, Abeßer M, Eder Negrin P, Cellini A, Nickel A, Nikolaev VO, Hofmann F, Schuh K, Schweda F, Kuhn M. Heart-Microcirculation Connection: Effects of ANP (Atrial Natriuretic Peptide) on Pericytes Participate in the Acute and Chronic Regulation of Arterial Blood Pressure. Hypertension (Dallas, Tex. : 1979). 76: 1637-1648. PMID 32951468 DOI: 10.1161/Hypertensionaha.120.15772 |
0.329 |
|
| 2020 |
Dolce B, Christ T, Grammatika Pavlidou N, Yildirim Y, Reichenspurner H, Eschenhagen T, Nikolaev VO, Kaumann AJ, Molina CE. Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 32949251 DOI: 10.1007/S00210-020-01968-1 |
0.303 |
|
| 2020 |
Diering S, Stathopoulou K, Goetz M, Rathjens L, Harder S, Piasecki A, Raabe J, Schulz S, Brandt M, Pflaumenbaum J, Fuchs U, Donzelli S, Sadayappan S, Nikolaev VO, Flenner F, et al. Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents. The Journal of Biological Chemistry. PMID 32868295 DOI: 10.1074/Jbc.Ra120.014467 |
0.423 |
|
| 2020 |
Gruteser N, Kohlhas V, Balfanz S, Franzen A, Günther A, Offenhäusser A, Müller F, Nikolaev V, Lohse MJ, Baumann A. Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides. Bmc Biotechnology. 20: 47. PMID 32854679 DOI: 10.1186/S12896-020-00633-Y |
0.586 |
|
| 2020 |
Heijman J, Muna AP, Veleva T, Molina CE, Sutanto H, Tekook MA, Wang Q, Abu-Taha I, Gorka M, Künzel S, El-Armouche A, Reichenspurner H, Kamler M, Nikolaev VO, Ravens U, et al. Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation. Circulation Research. PMID 32762493 DOI: 10.1161/Circresaha.120.316710 |
0.36 |
|
| 2020 |
Eiringhaus J, Wünsche CM, Tirilomis P, Herting J, Bork N, Nikolaev VO, Hasenfuss G, Sossalla S, Fischer TH. Sacubitrilat reduces pro-arrhythmogenic sarcoplasmic reticulum Ca leak in human ventricular cardiomyocytes of patients with end-stage heart failure. Esc Heart Failure. PMID 32710603 DOI: 10.1002/Ehf2.12918 |
0.365 |
|
| 2020 |
Li X, Li J, Martinez EC, Froese A, Passariello CL, Henshaw K, Rusconi F, Li Y, Yu Q, Thakur H, Nikolaev VO, Kapiloff MS. Calcineurin Aβ-Specific Anchoring Confers Isoform-Specific Compartmentation and Function in Pathological Cardiac Myocyte Hypertrophy. Circulation. PMID 32611257 DOI: 10.1161/Circulationaha.119.044893 |
0.463 |
|
| 2020 |
Hofhuis J, Bersch K, Wagner S, Molina C, Fakuade FE, Iyer LM, Streckfuss-Bömeke K, Toischer K, Zelarayán LC, Voigt N, Nikolaev VO, Maier LS, Klinge L, Thoms S. Dysferlin links excitation-contraction coupling to structure and maintenance of the cardiac transverse-axial tubule system. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 32572487 DOI: 10.1093/Europace/Euaa093 |
0.366 |
|
| 2020 |
Wölfel A, Sättele M, Zechmeister C, Nikolaev VO, Lohse MJ, Boege F, Jahns R, Boivin-Jahns V. Unmasking features of the auto-epitope essential for β -adrenoceptor activation by autoantibodies in chronic heart failure. Esc Heart Failure. PMID 32436653 DOI: 10.1002/Ehf2.12747 |
0.584 |
|
| 2020 |
Kannabiran SA, Gosejacob D, Niemann B, Nikolaev VO, Pfeifer A. Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β and β-adrenoceptor signalling. Molecular Metabolism. 100986. PMID 32247064 DOI: 10.1016/J.Molmet.2020.100986 |
0.44 |
|
| 2020 |
Schobesberger S, Wright PT, Poulet C, Sanchez Alonso Mardones JL, Mansfield C, Friebe A, Harding SE, Balligand JL, Nikolaev VO, Gorelik J. β-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes. Elife. 9. PMID 32228862 DOI: 10.7554/Elife.52221 |
0.808 |
|
| 2020 |
Cuello F, Nikolaev VO. Cardiac cGMP signaling in health and disease: location, location, location. Journal of Cardiovascular Pharmacology. PMID 32040034 DOI: 10.1097/Fjc.0000000000000802 |
0.399 |
|
| 2020 |
Zuo H, Trombetta-Lima M, Heijink IH, van der Veen CHTJ, Hesse L, Faber KN, Poppinga WJ, Maarsingh H, Nikolaev VO, Schmidt AM. A-Kinase Anchoring Proteins Diminish TGF-β/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition. Cells. 9. PMID 32028718 DOI: 10.3390/Cells9020356 |
0.344 |
|
| 2020 |
Kaschubowski KE, Kraft AE, Nikolaev VO, Haag F. Using FRET-Based Fluorescent Sensors to Monitor Cytosolic and Membrane-Proximal Extracellular ATP Levels. Methods in Molecular Biology (Clifton, N.J.). 2041: 223-231. PMID 31646492 DOI: 10.1007/978-1-4939-9717-6_16 |
0.339 |
|
| 2020 |
Schobesberger S, Wright PT, Poulet C, Mardones JLSA, Mansfield C, Friebe A, Harding SE, Balligand J, Nikolaev VO, Gorelik J. Author response: β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes Elife. DOI: 10.7554/Elife.52221.Sa2 |
0.772 |
|
| 2020 |
Huebscher D, Borchert T, Hasenfuss G, Nikolaev V, Streckfuss-Boemeke K. Role of phosphodiesterases in the development of takotsubo syndrome European Heart Journal. 41. DOI: 10.1093/ehjci/ehaa946.3677 |
0.351 |
|
| 2019 |
Dikolayev V, Tuganbekov T, Nikolaev VO. Visualizing Cyclic Adenosine Monophosphate in Cardiac Microdomains Involved in Ion Homeostasis. Frontiers in Physiology. 10: 1406. PMID 31849691 DOI: 10.3389/Fphys.2019.01406 |
0.419 |
|
| 2019 |
Ramuz M, Hasan A, Gruscheski L, Diakonov I, Pavlaki N, Nikolaev VO, Harding S, Dunsby C, Gorelik J. A Software Tool for High-Throughput Real-Time Measurement of Intensity-Based Ratio-Metric FRET. Cells. 8. PMID 31795419 DOI: 10.3390/Cells8121541 |
0.746 |
|
| 2019 |
Bork NI, Molina CE, Nikolaev VO. cGMP signalling in cardiomyocyte microdomains. Biochemical Society Transactions. PMID 31652306 DOI: 10.1042/Bst20190225 |
0.44 |
|
| 2019 |
Denwood G, Tarasov A, Salehi A, Vergari E, Ramracheya R, Takahashi H, Nikolaev VO, Seino S, Gribble F, Reimann F, Rorsman P, Zhang Q. Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca release. The Journal of General Physiology. PMID 31358556 DOI: 10.1085/Jgp.201912351 |
0.317 |
|
| 2019 |
Stathopoulou K, Schobesberger S, Bork NI, Sprenger JU, Perera RK, Sotoud H, Geertz B, David JP, Christ T, Nikolaev VO, Cuello F. Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes. Cellular Signalling. 63: 109362. PMID 31344438 DOI: 10.1016/J.Cellsig.2019.109362 |
0.789 |
|
| 2019 |
Bull Melsom C, Cosson MV, Ørstavik Ø, Lai NC, Hammond HK, Osnes JB, Skomedal T, Nikolaev V, Levy FO, Krobert KA. Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. Plos One. 14: e0218110. PMID 31173603 DOI: 10.1371/Journal.Pone.0218110 |
0.398 |
|
| 2019 |
Egbert JR, Fahey PG, Reimer J, Owen CM, Evsikov AV, Nikolaev VO, Griesbeck O, Ray RS, Tolias AS, Jaffe LA. Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles†. Biology of Reproduction. PMID 31087036 DOI: 10.1093/Biolre/Ioz085 |
0.311 |
|
| 2019 |
Trautsch I, Heta E, Soong PL, Levent E, Nikolaev VO, Bogeski I, Katschinski DM, Mayr M, Zimmermann WH. Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium. Frontiers in Physiology. 10: 272. PMID 31024328 DOI: 10.3389/Fphys.2019.00272 |
0.375 |
|
| 2019 |
Johnsen B, Kaschubowski KE, Nader S, Schneider E, Nicola JA, Fliegert R, Wolf IMA, Guse AH, Nikolaev VO, Koch-Nolte F, Haag F. P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP. Purinergic Signalling. PMID 31016551 DOI: 10.1007/S11302-019-09654-5 |
0.348 |
|
| 2019 |
Eiringhaus J, Herting J, Schatter F, Nikolaev VO, Sprenger J, Wang Y, Köhn M, Zabel M, El-Armouche A, Hasenfuss G, Sossalla S, Fischer TH. Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling. Basic Research in Cardiology. 114: 13. PMID 30788598 DOI: 10.1007/S00395-019-0720-7 |
0.324 |
|
| 2019 |
Fliegert R, Heeren J, Koch-Nolte F, Nikolaev VO, Lohr C, Meier C, Guse AH. Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation. Biochemical Society Transactions. PMID 30674608 DOI: 10.1042/Bst20180419 |
0.321 |
|
| 2019 |
Grammatika Pavlidou N, Pecha S, Reichenspurner H, Christ T, Nikolaev VO, Molina CE. P2869Role of PDE8 in cAMP dynamics in human atrial fibrillation European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz748.1177 |
0.373 |
|
| 2019 |
Bork NI, Pavlidou NG, Reiter B, Reichenspurner H, Christ T, Nikolaev VO, Molina CE. P2863Regional specific remodeling of cGMP pathway in human atrial fibrillation European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz748.1172 |
0.388 |
|
| 2019 |
Petersen J, Kloth B, Grammatika-Pavlidou N, Eschenhagen T, Reichenspurner H, Nikolaev VO, Christ T, Molina CE, Girdauskas E. P5992Why aortic valve disease may persist after surgery? A joint basic science - Clinical effort European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz746.0713 |
0.341 |
|
| 2019 |
Huebscher D, Borchert T, Hasenfuss G, Nikolaev V, Streckfuss-Boemeke K. 3074Analyzing the regulation of a catecholamine-dependent altered cAMP signaling in a patient-specific induced pluripotent stem cell takotsubo-model European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz745.0030 |
0.468 |
|
| 2018 |
Ruthenbeck A, Marangoni E, Diercks BP, Krüger A, Froese A, Bork NI, Nikolaev VO, Guse AH, Meier C. Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays. Molecules (Basel, Switzerland). 23. PMID 30428589 DOI: 10.3390/Molecules23112960 |
0.374 |
|
| 2018 |
Bastug-Özel Z, Wright PT, Kraft AE, Pavlovic D, Howie J, Froese A, Fuller W, Gorelik J, Shattock MJ, Nikolaev VO. Heart failure leads to altered β2-adrenoceptor/cAMP dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain: Bastug et al. Phospholemman cAMP microdomain. Cardiovascular Research. PMID 30165515 DOI: 10.1093/Cvr/Cvy221 |
0.81 |
|
| 2018 |
Subramanian H, Froese A, Jönsson P, Schmidt H, Gorelik J, Nikolaev VO. Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP. Nature Communications. 9: 2446. PMID 29934640 DOI: 10.1038/S41467-018-04891-5 |
0.767 |
|
| 2018 |
Jungen C, Scherschel K, Bork NI, Kuklik P, Eickholt C, Kniep H, Klatt N, Willems S, Nikolaev VO, Meyer C. Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System. Journal of Visualized Experiments : Jove. PMID 29889210 DOI: 10.3791/57617 |
0.394 |
|
| 2018 |
Zuo H, Han B, Poppinga WJ, Ringnalda L, Kistemaker LEM, Halayko AJ, Gosens R, Nikolaev VO, Schmidt M. Cigarette Smoke Upregulates PDE3 and PDE4 to Decrease cAMP in Airway Cells. British Journal of Pharmacology. PMID 29722436 DOI: 10.1111/Bph.14347 |
0.316 |
|
| 2018 |
Wright PT, Bhogal NK, Diakonov I, Pannell LMK, Perera RK, Bork NI, Schobesberger S, Lucarelli C, Faggian G, Alvarez-Laviada A, Zaccolo M, Kamp TJ, Balijepalli RC, Lyon AR, Harding SE, ... Nikolaev VO, et al. Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in βAR-cAMP Responsiveness in Murine Hearts. Cell Reports. 23: 459-469. PMID 29642004 DOI: 10.1016/J.Celrep.2018.03.053 |
0.802 |
|
| 2018 |
Špiranec K, Chen W, Werner F, Nikolaev VO, Naruke T, Koch F, Werner A, Eder-Negrin P, Diéguez-Hurtado R, Adams RH, Baba HA, Schmidt H, Schuh K, Skryabin BV, Movahedi K, et al. Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure. Circulation. PMID 29626067 DOI: 10.1161/Circulationaha.117.033383 |
0.324 |
|
| 2018 |
Movahedi K, Wiegmann R, De Vlaminck K, Van Ginderachter JA, Nikolaev VO. RoMo: An efficient strategy for functional mosaic analysis via stochastic Cre recombination and gene targeting in the ROSA26 locus. Biotechnology and Bioengineering. PMID 29573361 DOI: 10.1002/Bit.26594 |
0.341 |
|
| 2018 |
Flenner F, Arlt N, Nasib M, Schobesberger S, Koch T, Ravens U, Friedrich F, Nikolaev V, Christ T, Stehr SN. In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but not to Ca2+ Handling or β-Adrenoceptor Signaling. Anesthesiology. PMID 29547406 DOI: 10.1097/Aln.0000000000002180 |
0.78 |
|
| 2018 |
Bork NI, Nikolaev VO. cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging. International Journal of Molecular Sciences. 19. PMID 29534460 DOI: 10.3390/Ijms19030801 |
0.35 |
|
| 2018 |
Pavlaki N, Nikolaev VO. Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes. Journal of Cardiovascular Development and Disease. 5. PMID 29367582 DOI: 10.3390/Jcdd5010004 |
0.385 |
|
| 2018 |
Dünnes S, Voussen B, Aue A, Groneberg K, Nikolaev V, Groneberg D, Friebe A. Phosphodiesterase 3A expression and activity in the murine vasculature is influenced by NO-sensitive guanylyl cyclase. Pflugers Archiv : European Journal of Physiology. 470: 693-702. PMID 29294149 DOI: 10.1007/S00424-017-2106-8 |
0.363 |
|
| 2018 |
Streckfuss-Boemeke K, Huebscher D, Borchert T, Nikolaev VO, Sossalla ST, Templin C, Hasenfuss G. P1851Catecholamine-dependent cAMP signaling in a patient-specific induced pluripotent stem cell takotsubo-model European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy565.P1851 |
0.325 |
|
| 2018 |
Berisha F, Goetz KR, Wegener JW, Blankenberg S, Marks AR, Lehnart SE, Nikolaev VO. P933Direct monitoring of cAMP at cardiac ryanodine receptor reveals altered beta2-adrenoceptor dependent regulation in hypertrophy European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy564.P933 |
0.426 |
|
| 2018 |
Kraft A, Conti M, Nikolaev V. Phosphodiesterases 4B and 4D differentially regulate cAMP signaling in calcium handling microdomains of adult mouse cardiomyocytes Journal of Molecular and Cellular Cardiology. 120: 40. DOI: 10.1016/J.Yjmcc.2018.05.121 |
0.435 |
|
| 2017 |
Perera RK, Fischer TH, Wagner M, Dewenter M, Vettel C, Bork NI, Maier LS, Conti M, Wess J, El-Armouche A, Hasenfuß G, Nikolaev VO. Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4. Scientific Reports. 7: 15222. PMID 29123207 DOI: 10.1038/S41598-017-15632-X |
0.44 |
|
| 2017 |
Frankenreiter S, Bednarczyk P, Kniess A, Bork N, Straubinger J, Koprowski P, Wrzosek A, Mohr E, Logan A, Murphy MP, Gawaz M, Krieg T, Szewczyk A, Nikolaev VO, Ruth P, et al. cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels. Circulation. PMID 29051185 DOI: 10.1161/Circulationaha.117.028723 |
0.378 |
|
| 2017 |
Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, ... ... Nikolaev VO, ... ... Nikolaev VO, ... ... Nikolaev VO, ... ... Nikolaev VO, et al. Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacology & Toxicology. 18: 64. PMID 29035170 DOI: 10.1186/s40360-017-0170-5 |
0.733 |
|
| 2017 |
Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King SB, ... Nikolaev VO, et al. Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity. Scientific Reports. 7: 9938. PMID 28855531 DOI: 10.1038/S41598-017-09275-1 |
0.783 |
|
| 2017 |
Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, ... ... Nikolaev VO, et al. Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy. Journal of the American College of Cardiology. 70: 975-991. PMID 28818208 DOI: 10.1016/J.Jacc.2017.06.061 |
0.344 |
|
| 2017 |
Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. T-tubule remodelling disturbs localised β2-adrenergic signalling in rat ventricular myocyte during the progression of heart failure. Cardiovascular Research. PMID 28505272 DOI: 10.1093/Cvr/Cvx074 |
0.792 |
|
| 2017 |
Kraft AE, Nikolaev VO. FRET Microscopy for Real-Time Visualization of Second Messengers in Living Cells. Methods in Molecular Biology (Clifton, N.J.). 1563: 85-90. PMID 28324603 DOI: 10.1007/978-1-4939-6810-7_6 |
0.335 |
|
| 2017 |
Berisha F, Nikolaev VO. Cyclic nucleotide imaging and cardiovascular disease. Pharmacology & Therapeutics. PMID 28216026 DOI: 10.1016/J.Pharmthera.2017.02.038 |
0.381 |
|
| 2017 |
Jungen C, Scherschel K, Eickholt C, Kuklik P, Klatt N, Bork N, Salzbrunn T, Alken F, Angendohr S, Klene C, Mester J, Klöcker N, Veldkamp MW, Schumacher U, Willems S, ... Nikolaev VO, et al. Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias. Nature Communications. 8: 14155. PMID 28128201 DOI: 10.1038/Ncomms14155 |
0.342 |
|
| 2016 |
Sprenger JU, Bork NI, Herting J, Fischer TH, Nikolaev VO. Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET. Plos One. 11: e0167974. PMID 27930744 DOI: 10.1371/Journal.Pone.0167974 |
0.404 |
|
| 2016 |
Abu-Taha IH, Heijman J, Hippe HJ, Wolf NM, El-Armouche A, Nikolaev VO, Schäfer M, Würtz C, Neef S, Voigt N, Baczkó I, Varró A, Müller M, Meder B, Katus HA, et al. Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure. Circulation. PMID 27927712 DOI: 10.1161/Circulationaha.116.022852 |
0.432 |
|
| 2016 |
Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, et al. Axial tubule junctions control rapid calcium signaling in atria. The Journal of Clinical Investigation. PMID 27643434 DOI: 10.1172/Jci88241 |
0.382 |
|
| 2016 |
Ismail S, Gherardi MJ, Froese A, Zanoun M, Gigoux V, Clerc P, Gaits-Iacovoni F, Steyaert J, Nikolaev VO, Fourmy D. Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes. Biochemical Pharmacology. PMID 27641811 DOI: 10.1016/J.Bcp.2016.09.009 |
0.42 |
|
| 2016 |
Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal NK, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circulation Research. PMID 27572487 DOI: 10.1161/Circresaha.116.308698 |
0.774 |
|
| 2016 |
Swain L, Kesemeyer A, Meyer-Roxlau S, Vettel C, Zieseniss A, Güntsch A, Jatho A, Becker A, Nanadikar MS, Morgan B, Dennerlein S, Shah AM, El-Armouche A, Nikolaev VO, Katschinski DM. Redox Imaging Using Cardiac Myocyte Specific Transgenic Biosensor Mice. Circulation Research. PMID 27553648 DOI: 10.1161/Circresaha.116.309551 |
0.33 |
|
| 2016 |
Akiyama H, Fukuda T, Tojima T, Nikolaev VO, Kamiguchi H. Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5636-49. PMID 27194341 DOI: 10.1523/Jneurosci.3596-15.2016 |
0.327 |
|
| 2016 |
Chen W, Spitzl A, Mathes DS, Nikolaev VO, Werner F, Weirather J, Spiranec K, Röck K, Fischer JW, Kämmerer U, Stegner D, Baba HA, Hofmann U, Frantz S, Kuhn M. Endothelial Actions of ANP Enhance Myocardial Inflammatory Infiltration in the Early Phase After Acute Infarction. Circulation Research. PMID 27142162 DOI: 10.1161/Circresaha.115.307196 |
0.323 |
|
| 2016 |
Burgers PP, Bruystens J, Burnley RJ, Nikolaev VO, Keshwani M, Wu J, Janssen BJ, Taylor SS, Heck AJ, Scholten A. Structure of smAKAP and its regulation by PKA-mediated phosphorylation. The Febs Journal. PMID 27028580 DOI: 10.1111/Febs.13726 |
0.315 |
|
| 2016 |
Zuo H, Poppinga W, Zeisberg E, Nikolaev VO, Schmidt M. Monitoring local pulmonary cAMP levels : combining precision cut lung slice (PCLS) and fluorescence resonance energy transfer (FRET) technologies in mice American Journal of Respiratory and Critical Care Medicine. 193. DOI: 10.1183/13993003.Congress-2016.Pa5055 |
0.388 |
|
| 2015 |
Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, et al. POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking. The Journal of Clinical Investigation. PMID 26642364 DOI: 10.1172/Jci79562 |
0.324 |
|
| 2015 |
Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, ... Nikolaev VO, et al. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation. The Journal of Clinical Investigation. PMID 26571400 DOI: 10.1172/Jci81975 |
0.695 |
|
| 2015 |
Froese A, Nikolaev VO. Imaging alterations of cardiomyocyte cAMP microdomains in disease. Frontiers in Pharmacology. 6: 172. PMID 26379548 DOI: 10.3389/Fphar.2015.00172 |
0.437 |
|
| 2015 |
Straubinger J, Schöttle V, Bork N, Subramanian H, Dünnes S, Russwurm M, Gawaz M, Friebe A, Nemer M, Nikolaev VO, Lukowski R. Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling. The Journal of Pharmacology and Experimental Therapeutics. 354: 406-16. PMID 26157043 DOI: 10.1124/Jpet.115.226092 |
0.414 |
|
| 2015 |
Fischer TH, Herting J, Mason FE, Hartmann N, Watanabe S, Nikolaev VO, Sprenger JU, Fan P, Yao L, Popov AF, Danner BC, Schöndube F, Belardinelli L, Hasenfuss G, Maier LS, et al. Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII. Cardiovascular Research. 107: 184-96. PMID 25990311 DOI: 10.1093/Cvr/Cvv153 |
0.339 |
|
| 2015 |
Reddy GR, Subramanian H, Birk A, Milde M, Nikolaev VO, Bünemann M. Adenylyl cyclases 5 and 6 underlie PIP3-dependent regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 3458-71. PMID 25931510 DOI: 10.1096/Fj.14-268466 |
0.672 |
|
| 2015 |
Sprenger JU, Perera RK, Steinbrecher JH, Lehnart SE, Maier LS, Hasenfuss G, Nikolaev VO. In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease. Nature Communications. 6: 6965. PMID 25917898 DOI: 10.1038/Ncomms7965 |
0.47 |
|
| 2015 |
Shuhaibar LC, Egbert JR, Norris RP, Lampe PD, Nikolaev VO, Thunemann M, Wen L, Feil R, Jaffe LA. Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles. Proceedings of the National Academy of Sciences of the United States of America. 112: 5527-32. PMID 25775542 DOI: 10.1073/Pnas.1423598112 |
0.376 |
|
| 2015 |
Boivin V, Beyersdorf N, Palm D, Nikolaev VO, Schlipp A, Müller J, Schmidt D, Kocoski V, Kerkau T, Hünig T, Ertl G, Lohse MJ, Jahns R. Novel receptor-derived cyclopeptides to treat heart failure caused by anti-β1-adrenoceptor antibodies in a human-analogous rat model. Plos One. 10: e0117589. PMID 25700031 DOI: 10.1371/Journal.Pone.0117589 |
0.53 |
|
| 2015 |
Perera RK, Sprenger JU, Steinbrecher JH, Hübscher D, Lehnart SE, Abesser M, Schuh K, El-Armouche A, Nikolaev VO. Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy. Circulation Research. 116: 1304-11. PMID 25688144 DOI: 10.1161/Circresaha.116.306082 |
0.448 |
|
| 2015 |
Boivin V, Beyersdorf N, Palm D, Nikolaev VO, Schlipp A, Müller J, Schmidt D, Kocoski V, Kerkau T, Hunig T, Ertl G, Lohse MJ, Jahns R. Morphometric analysis of rat hearts (therapy-study). Plos One. DOI: 10.1371/Journal.Pone.0117589.T003 |
0.509 |
|
| 2015 |
Subramanian H, Froese A, Hübscher D, Götz KR, Nikolaev VO. Direct visualization of cGMP microdomains in adult cardiomyocytes Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A91 |
0.341 |
|
| 2015 |
Milde M, Thunemann M, Subramanian H, Ganzenberg K, Aparicio J, Gülcüler G, Nikolaev VO, Feil R. Comparative analysis of established and new biosensors for cyclic nucleotides Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A68 |
0.385 |
|
| 2015 |
Friebe A, Dünnes S, Nikolaev V, Lies B, Groneberg D. Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A52 |
0.386 |
|
| 2015 |
Perera RK, Subramanian H, Froese A, Hübscher D, Götz KR, Nikolaev VO. cGMP and cardiac hypertrophy Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A12 |
0.406 |
|
| 2014 |
Nakagawa H, Oberwinkler H, Nikolaev VO, Gaßner B, Umbenhauer S, Wagner H, Saito Y, Baba HA, Frantz S, Kuhn M. Atrial natriuretic peptide locally counteracts the deleterious effects of cardiomyocyte mineralocorticoid receptor activation. Circulation. Heart Failure. 7: 814-21. PMID 25027872 DOI: 10.1161/Circheartfailure.113.000885 |
0.461 |
|
| 2014 |
Dybkova N, Wagner S, Backs J, Hund TJ, Mohler PJ, Sowa T, Nikolaev VO, Maier LS. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77. PMID 24812278 DOI: 10.1093/Cvr/Cvu120 |
0.401 |
|
| 2014 |
Agarwal SR, Yang PC, Rice M, Singer CA, Nikolaev VO, Lohse MJ, Clancy CE, Harvey RD. Role of membrane microdomains in compartmentation of cAMP signaling. Plos One. 9: e95835. PMID 24752595 DOI: 10.1371/Journal.Pone.0095835 |
0.563 |
|
| 2014 |
Götz KR, Sprenger JU, Perera RK, Steinbrecher JH, Lehnart SE, Kuhn M, Gorelik J, Balligand JL, Nikolaev VO. Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes. Circulation Research. 114: 1235-45. PMID 24599804 DOI: 10.1161/Circresaha.114.302437 |
0.715 |
|
| 2014 |
Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A. PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways American Journal of Physiology - Heart and Circulatory Physiology. 306: H1246-H1252. PMID 24531807 DOI: 10.1152/Ajpheart.00852.2013 |
0.433 |
|
| 2014 |
Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J. Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. Journal of Molecular and Cellular Cardiology. 67: 38-48. PMID 24345421 DOI: 10.1016/J.Yjmcc.2013.12.003 |
0.81 |
|
| 2014 |
Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, et al. Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. Circulation. 129: 451-62. PMID 24190960 DOI: 10.1161/Circulationaha.113.004940 |
0.421 |
|
| 2014 |
Cazabat L, Ragazzon B, Varin A, Potier-Cartereau M, Vandier C, Vezzosi D, Risk-Rabin M, Guellich A, Schittl J, Lechêne P, Richter W, Nikolaev VO, Zhang J, Bertherat J, Vandecasteele G. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. Human Molecular Genetics. 23: 1163-74. PMID 24122441 DOI: 10.1093/Hmg/Ddt510 |
0.396 |
|
| 2014 |
Perera RK, Steinbrecher JH, Lehnart SE, Nikolaev VO. P608ANP potentiates catecholaminergic stress in early cardiac disease Cardiovascular Research. 103: S110.1-S110. DOI: 10.1093/Cvr/Cvu098.37 |
0.495 |
|
| 2014 |
Dubois-Deruy E, Gelinas R, Hammond J, Gotz K, Nikolaev V, Manoury B, Esfahani H, Dessy C, Bertrand L, Balligand J. 290β-3 adrenoreceptors protect from hypertrophic remodelling through nitric oxide synthase & AMP-activated protein kinase dependent signaling pathways Cardiovascular Research. 103: S53.1-S53. DOI: 10.1093/Cvr/Cvu087.4 |
0.377 |
|
| 2013 |
Couto A, Oda S, Nikolaev VO, Soltesz Z, de Bono M. In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensor. Proceedings of the National Academy of Sciences of the United States of America. 110: E3301-10. PMID 23940325 DOI: 10.1073/Pnas.1217428110 |
0.344 |
|
| 2013 |
Lowther KM, Uliasz TF, Götz KR, Nikolaev VO, Mehlmann LM. Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells. Plos One. 8: e65365. PMID 23826079 DOI: 10.1371/Journal.Pone.0065365 |
0.459 |
|
| 2013 |
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, ... ... Nikolaev VO, et al. Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. Journal of the American College of Cardiology. 62: 1596-606. PMID 23810893 DOI: 10.1016/J.Jacc.2013.05.057 |
0.478 |
|
| 2013 |
Götz KR, Nikolaev VO. Advances and techniques to measure cGMP in intact cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.). 1020: 121-9. PMID 23709029 DOI: 10.1007/978-1-62703-459-3_7 |
0.355 |
|
| 2013 |
Sprenger JU, Nikolaev VO. Biophysical techniques for detection of cAMP and cGMP in living cells. International Journal of Molecular Sciences. 14: 8025-46. PMID 23584022 DOI: 10.3390/Ijms14048025 |
0.375 |
|
| 2013 |
Perera RK, Nikolaev VO. Compartmentation of cAMP signalling in cardiomyocytes in health and disease. Acta Physiologica (Oxford, England). 207: 650-62. PMID 23383621 DOI: 10.1111/apha.12077 |
0.383 |
|
| 2013 |
Jaffe LA, Egbert JR, Shuhaibar LC, Wen L, Thunemann M, Feil R, Nikolaev V, Robinson JW, Potter LR. Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-P31 |
0.373 |
|
| 2013 |
Götz KR, Nikolaev VO. PDE3 is the major cGMP-PDE in adult mouse ventricular cardiomyocytes Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-P26 |
0.367 |
|
| 2013 |
Agarwal SR, Rice M, Singer CA, Nikolaev V, Lohse M, Harvey RD. Regulation of CAMP Compartmentation by Membrane Microdomains Biophysical Journal. 104: 612a. DOI: 10.1016/J.Bpj.2012.11.3390 |
0.535 |
|
| 2012 |
Ghigo A, Perino A, Mehel H, Zahradníková A, Morello F, Leroy J, Nikolaev VO, Damilano F, Cimino J, De Luca E, Richter W, Westenbroek R, Catterall WA, Zhang J, Yan C, et al. Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. Circulation. 126: 2073-83. PMID 23008439 DOI: 10.1161/Circulationaha.112.114074 |
0.467 |
|
| 2012 |
Sprenger JU, Perera RK, Götz KR, Nikolaev VO. FRET microscopy for real-time monitoring of signaling events in live cells using unimolecular biosensors. Journal of Visualized Experiments : Jove. e4081. PMID 22929080 DOI: 10.3791/4081 |
0.389 |
|
| 2012 |
Paur H, Wright PT, Sikkel MB, Tranter MH, Mansfield C, O'Gara P, Stuckey DJ, Nikolaev VO, Diakonov I, Pannell L, Gong H, Sun H, Peters NS, Petrou M, Zheng Z, et al. High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation. 126: 697-706. PMID 22732314 DOI: 10.1161/Circulationaha.112.111591 |
0.824 |
|
| 2012 |
Gambaryan S, Butt E, Kobsar A, Geiger J, Rukoyatkina N, Parnova R, Nikolaev VO, Walter U. The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells. British Journal of Pharmacology. 167: 826-38. PMID 22612416 DOI: 10.1111/J.1476-5381.2012.02044.X |
0.341 |
|
| 2012 |
Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circulation. Heart Failure. 5: 357-65. PMID 22456061 DOI: 10.1161/Circheartfailure.111.964692 |
0.831 |
|
| 2012 |
Froese A, Breher SS, Waldeyer C, Schindler RF, Nikolaev VO, Rinné S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, et al. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. The Journal of Clinical Investigation. 122: 1119-30. PMID 22354168 DOI: 10.1172/Jci59410 |
0.397 |
|
| 2012 |
Mindukshev I, Gambaryan S, Kehrer L, Schuetz C, Kobsar A, Rukoyatkina N, Nikolaev VO, Krivchenko A, Watson SP, Walter U, Geiger J. Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 50: 1253-62. PMID 22149738 DOI: 10.1515/Cclm.2011.817 |
0.309 |
|
| 2012 |
Chen W, Gassner B, Börner S, Nikolaev VO, Schlegel N, Waschke J, Steinbronn N, Strasser R, Kuhn M. Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway. Cardiovascular Research. 93: 141-51. PMID 22025581 DOI: 10.1093/Cvr/Cvr279 |
0.338 |
|
| 2012 |
Wright P, Pannell L, Nikolaev V, Lyon A, Harding S, Gorelik J. 16 Imaging Regional Differences in Beta-2 Adrenergic Receptor Function at The Cellular Level Heart. 98: A5.3-A5. DOI: 10.1136/Heartjnl-2012-302951.016 |
0.809 |
|
| 2011 |
Klaiber M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Yang RB, Völker K, Gassner B, Oberwinkler H, Feil R, Freichel M, Groschner K, Skryabin BV, Frantz S, Birnbaumer L, et al. A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide. Proceedings of the National Academy of Sciences of the United States of America. 108: 18500-5. PMID 22027011 DOI: 10.1073/Pnas.1103300108 |
0.433 |
|
| 2011 |
Miragoli M, Kadir SH, Sheppard MN, Salvarani N, Virta M, Wells S, Lab MJ, Nikolaev VO, Moshkov A, Hague WM, Rohr S, Williamson C, Gorelik J. A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology (Baltimore, Md.). 54: 1282-92. PMID 21809354 DOI: 10.1002/Hep.24492 |
0.795 |
|
| 2011 |
Börner S, Schwede F, Schlipp A, Berisha F, Calebiro D, Lohse MJ, Nikolaev VO. FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells. Nature Protocols. 6: 427-38. PMID 21412271 DOI: 10.1038/Nprot.2010.198 |
0.722 |
|
| 2011 |
Lowther KM, Nikolaev VO, Mehlmann LM. Endocytosis in the mouse oocyte and its contribution to cAMP signaling during meiotic arrest. Reproduction (Cambridge, England). 141: 737-47. PMID 21411693 DOI: 10.1530/Rep-10-0461 |
0.437 |
|
| 2011 |
Frölich N, Dees C, Paetz C, Ren X, Lohse MJ, Nikolaev VO, Zenk MH. Distinct pharmacological properties of morphine metabolites at G i-protein and β-arrestin signaling pathways activated by the human μ-opioid receptor Biochemical Pharmacology. 81: 1248-1254. PMID 21396918 DOI: 10.1016/J.Bcp.2011.03.001 |
0.497 |
|
| 2011 |
Miragoli M, Moshkov A, Novak P, Shevchuk A, Nikolaev VO, El-Hamamsy I, Potter CM, Wright P, Kadir SH, Lyon AR, Mitchell JA, Chester AH, Klenerman D, Lab MJ, Korchev YE, et al. Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells. Journal of the Royal Society, Interface / the Royal Society. 8: 913-25. PMID 21325316 DOI: 10.1098/Rsif.2010.0597 |
0.782 |
|
| 2011 |
Kuhn M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Völker K, Gaßner B, Feil R, Freichel M, Pongs O, Klaiber M. A novel pathway of cGMP Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-O28 |
0.44 |
|
| 2011 |
Liao MC, Mutoh H, Iwamoto Y, Raad N, Nikolaev V, Luther S, Lehnart S, Wagner S, Maier L, Stühmer W, Knöpfel T, Zimmermann W. Voltage Sensitive Protein 2.3: A Novel Tool to Study Sarcolemmal Structure and Electrical Activity in Mouse Hearts Biophysical Journal. 100: 575a-576a. DOI: 10.1016/J.Bpj.2010.12.3328 |
0.357 |
|
| 2010 |
Norris RP, Freudzon M, Nikolaev VO, Jaffe LA. Epidermal growth factor receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to LH. Reproduction (Cambridge, England). 140: 655-62. PMID 20826538 DOI: 10.1530/Rep-10-0288 |
0.338 |
|
| 2010 |
Jacobs S, Calebiro D, Nikolaev VO, Lohse MJ, Schulz S. Real-time monitoring of somatostatin receptor-cAMP signaling in live pituitary. Endocrinology. 151: 4560-5. PMID 20610560 DOI: 10.1210/En.2010-0341 |
0.759 |
|
| 2010 |
Castro LR, Gervasi N, Guiot E, Cavellini L, Nikolaev VO, Paupardin-Tritsch D, Vincent P. Type 4 phosphodiesterase plays different integrating roles in different cellular domains in pyramidal cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6143-51. PMID 20427672 DOI: 10.1523/Jneurosci.5851-09.2010 |
0.42 |
|
| 2010 |
Calebiro D, Nikolaev VO, Lohse MJ. Imaging of persistent cAMP signaling by internalized G protein-coupled receptors. Journal of Molecular Endocrinology. 45: 1-8. PMID 20378719 DOI: 10.1677/Jme-10-0014 |
0.764 |
|
| 2010 |
Calebiro D, Nikolaev VO, Persani L, Lohse MJ. Signaling by internalized G-protein-coupled receptors. Trends in Pharmacological Sciences. 31: 221-8. PMID 20303186 DOI: 10.1016/J.Tips.2010.02.002 |
0.766 |
|
| 2010 |
Sheikh Abdul Kadir SH, Miragoli M, Abu-Hayyeh S, Moshkov AV, Xie Q, Keitel V, Nikolaev VO, Williamson C, Gorelik J. Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes. Plos One. 5: e9689. PMID 20300620 DOI: 10.1371/Journal.Pone.0009689 |
0.797 |
|
| 2010 |
Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science (New York, N.Y.). 327: 1653-7. PMID 20185685 DOI: 10.1126/Science.1185988 |
0.826 |
|
| 2010 |
Maier-Peuschel M, Frölich N, Dees C, Hommers LG, Hoffmann C, Nikolaev VO, Lohse MJ. A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation. The Journal of Biological Chemistry. 285: 8793-800. PMID 20083608 DOI: 10.1074/Jbc.M109.098517 |
0.724 |
|
| 2010 |
Wachten S, Masada N, Ayling LJ, Ciruela A, Nikolaev VO, Lohse MJ, Cooper DM. Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells. Journal of Cell Science. 123: 95-106. PMID 20016070 DOI: 10.1242/Jcs.058594 |
0.555 |
|
| 2010 |
von Hayn K, Werthmann RC, Nikolaev VO, Hommers LG, Lohse MJ, Bünemann M. Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 298: C324-32. PMID 19889965 DOI: 10.1152/Ajpcell.00197.2009 |
0.715 |
|
| 2009 |
Calebiro D, Nikolaev VO, Gagliani MC, de Filippis T, Dees C, Tacchetti C, Persani L, Lohse MJ. Persistent cAMP-signals triggered by internalized G-protein-coupled receptors. Plos Biology. 7: e1000172. PMID 19688034 DOI: 10.1371/Journal.Pbio.1000172 |
0.766 |
|
| 2009 |
Adachi E, Kazoe Y, Sato Y, Suzuki Y, Urano T, Ueyama T, Saito N, Nikolaev VO, Lohse MJ, Tominaga M, Mogami H. A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy. PflüGers Archiv : European Journal of Physiology. 459: 227-34. PMID 19680684 DOI: 10.1007/S00424-009-0705-8 |
0.607 |
|
| 2009 |
Werthmann RC, von Hayn K, Nikolaev VO, Lohse MJ, Bünemann M. Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6. The Journal of Physiology. 587: 4091-104. PMID 19546162 DOI: 10.1113/Jphysiol.2009.172957 |
0.715 |
|
| 2009 |
Norris RP, Ratzan WJ, Freudzon M, Mehlmann LM, Krall J, Movsesian MA, Wang H, Ke H, Nikolaev VO, Jaffe LA. Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte. Development (Cambridge, England). 136: 1869-78. PMID 19429786 DOI: 10.1242/Dev.035238 |
0.366 |
|
| 2009 |
Nakagawa Y, Nagasawa M, Yamada S, Hara A, Mogami H, Nikolaev VO, Lohse MJ, Shigemura N, Ninomiya Y, Kojima I. Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. Plos One. 4: e5106. PMID 19352508 DOI: 10.1371/Journal.Pone.0005106 |
0.565 |
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| 2009 |
Mironov SL, Skorova E, Taschenberger G, Hartelt N, Nikolaev VO, Lohse MJ, Kügler S. Imaging cytoplasmic cAMP in mouse brainstem neurons. Bmc Neuroscience. 10: 29. PMID 19327133 DOI: 10.1186/1471-2202-10-29 |
0.558 |
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| 2009 |
Vilardaga JP, Bünemann M, Feinstein TN, Lambert N, Nikolaev VO, Engelhardt S, Lohse MJ, Hoffmann C. GPCR and G proteins: drug efficacy and activation in live cells. Molecular Endocrinology (Baltimore, Md.). 23: 590-9. PMID 19196832 DOI: 10.1210/Me.2008-0204 |
0.818 |
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| 2009 |
Nikolaev VO, Lohse MJ. Novel techniques for real-time monitoring of cGMP in living cells. Handbook of Experimental Pharmacology. 229-43. PMID 19089332 DOI: 10.1007/978-3-540-68964-5_11 |
0.499 |
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| 2009 |
Hartmann M, Völker K, Gaßner B, Schröter J, Dankworth B, Müller T, Nikolaev VO, Kuhn M. A splice variant of the guanylyl cyclase-A receptor interferes with atrial natriuretic peptide (ANP) signaling Bmc Pharmacology. 9. DOI: 10.1186/1471-2210-9-S1-P22 |
0.397 |
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| 2008 |
Hartmann M, Skryabin BV, Müller T, Gazinski A, Schröter J, Gassner B, Nikolaev VO, Bünemann M, Kuhn M. Alternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signaling. The Journal of Biological Chemistry. 283: 28313-20. PMID 18713751 DOI: 10.1074/Jbc.M805521200 |
0.662 |
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| 2008 |
Sassi Y, Lipskaia L, Vandecasteele G, Nikolaev VO, Hatem SN, Cohen Aubart F, Russel FG, Mougenot N, Vrignaud C, Lechat P, Lompré AM, Hulot JS. Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation. The Journal of Clinical Investigation. 118: 2747-57. PMID 18636120 DOI: 10.1172/Jci35067 |
0.351 |
|
| 2008 |
Müller II, Klingel K, Nikolaev VO, Jahns R, Gawaz MP, Weig HJ. Immunoadsorption in a 40 year old man with dilated cardiomyopathy and underlying active myocarditis. Clinical Research in Cardiology : Official Journal of the German Cardiac Society. 97: 787-90. PMID 18633566 DOI: 10.1007/S00392-008-0689-Y |
0.357 |
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| 2008 |
Iancu RV, Ramamurthy G, Warrier S, Nikolaev VO, Lohse MJ, Jones SW, Harvey RD. Cytoplasmic cAMP concentrations in intact cardiac myocytes. American Journal of Physiology. Cell Physiology. 295: C414-22. PMID 18550706 DOI: 10.1152/Ajpcell.00038.2008 |
0.639 |
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| 2008 |
Herget S, Lohse MJ, Nikolaev VO. Real-time monitoring of phosphodiesterase inhibition in intact cells. Cellular Signalling. 20: 1423-31. PMID 18467075 DOI: 10.1016/J.Cellsig.2008.03.011 |
0.575 |
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| 2008 |
Shafer OT, Kim DJ, Dunbar-Yaffe R, Nikolaev VO, Lohse MJ, Taghert PH. Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. Neuron. 58: 223-37. PMID 18439407 DOI: 10.1016/J.Neuron.2008.02.018 |
0.475 |
|
| 2008 |
Leroy J, Abi-Gerges A, Nikolaev VO, Richter W, Lechêne P, Mazet JL, Conti M, Fischmeister R, Vandecasteele G. Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases. Circulation Research. 102: 1091-100. PMID 18369156 DOI: 10.1161/Circresaha.107.167817 |
0.421 |
|
| 2008 |
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bünemann M. Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends in Pharmacological Sciences. 29: 159-65. PMID 18262662 DOI: 10.1016/J.Tips.2007.12.002 |
0.815 |
|
| 2008 |
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetics of G-protein-coupled receptor signals in intact cells. British Journal of Pharmacology. 153: S125-32. PMID 18193071 DOI: 10.1038/sj.bjp.0707656 |
0.775 |
|
| 2008 |
Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nature Chemical Biology. 4: 126-31. PMID 18193048 DOI: 10.1038/Nchembio.64 |
0.807 |
|
| 2008 |
BOIVIN V, NIKOLAEV V, SCHWARZBACH V, SCHLIPP A, YE Y, ANGERMANN C, ERTL G, LOHSE M, JAHNS R. Cardioprotective cyclic peptides and beta-blockers in the therapy of beta1-receptor antibody-induced cardiomyopathy: effects on phenotype and cardiac expression of ANP/BNP/Cytokines European Journal of Heart Failure Supplements. 7: 28-29. DOI: 10.1016/S1567-4215(08)60080-6 |
0.531 |
|
| 2008 |
SCHWARZBACH V, BOIVIN V, ROEDER T, NIKOLAEV V, KLINGEL K, ERTL G, LOHSE M, JAHNS R. Development of phenotype and expression of contractile proteins & molecular markers of heart failure over time in beta1-receptor antibody-induced immune-cardiomyopathy European Journal of Heart Failure Supplements. 7: 28-28. DOI: 10.1016/S1567-4215(08)60079-X |
0.558 |
|
| 2007 |
Lohse MJ, Bünemann M, Hoffmann C, Vilardaga JP, Nikolaev VO. Monitoring receptor signaling by intramolecular FRET. Current Opinion in Pharmacology. 7: 547-53. PMID 17919975 DOI: 10.1016/J.Coph.2007.08.007 |
0.807 |
|
| 2007 |
Lohse MJ, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells. Advances in Protein Chemistry. 74: 167-88. PMID 17854658 DOI: 10.1016/S0065-3233(07)74005-6 |
0.807 |
|
| 2007 |
Nikolaev VO, Boivin V, Störk S, Angermann CE, Ertl G, Lohse MJ, Jahns R. A novel fluorescence method for the rapid detection of functional beta1-adrenergic receptor autoantibodies in heart failure. Journal of the American College of Cardiology. 50: 423-31. PMID 17662395 DOI: 10.1016/J.Jacc.2007.03.051 |
0.532 |
|
| 2007 |
Nikolaev VO, Boettcher C, Dees C, Bünemann M, Lohse MJ, Zenk MH. Live cell monitoring of μ-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors Journal of Biological Chemistry. 282: 27126-27132. PMID 17616524 DOI: 10.1074/Jbc.M703272200 |
0.715 |
|
| 2007 |
Warrier S, Ramamurthy G, Eckert RL, Nikolaev VO, Lohse MJ, Harvey RD. cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes. The Journal of Physiology. 580: 765-76. PMID 17289786 DOI: 10.1113/Jphysiol.2006.124891 |
0.643 |
|
| 2007 |
Rochais F, Vilardaga JP, Nikolaev VO, Bünemann M, Lohse MJ, Engelhardt S. Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. The Journal of Clinical Investigation. 117: 229-35. PMID 17200720 DOI: 10.1172/Jci30012 |
0.798 |
|
| 2007 |
Nikolaev VO, Lohse MJ. Rapid monitoring of intracellular cGMP Bmc Pharmacology. 7. DOI: 10.1186/1471-2210-7-S1-S21 |
0.538 |
|
| 2007 |
Nikolaev VO, Herget S, Lohse MJ. FRET-based method for rapid screening of PDE-inhibitors in living cells Bmc Pharmacology. 7. DOI: 10.1186/1471-2210-7-S1-P43 |
0.521 |
|
| 2007 |
Hartmann M, Schröter J, Nikolaev VO, Sickmann A, Yang R, Kuhn M. Characterization of an epitope-tagged guanylyl cyclase-A receptor Bmc Pharmacology. 7. DOI: 10.1186/1471-2210-7-S1-P26 |
0.392 |
|
| 2007 |
Leroy J, Abi-Gerges A, Richter W, Nikolaev VO, Engelhardt S, Lohse MJ, Conti M, Fischmeister R, Vandecasteele G. Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 42: S49. DOI: 10.1016/J.Yjmcc.2007.03.139 |
0.651 |
|
| 2006 |
Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circulation Research. 99: 1084-91. PMID 17038640 DOI: 10.1161/01.Res.0000250046.69918.D5 |
0.772 |
|
| 2006 |
Harbeck MC, Chepurny O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells. Science's Stke : Signal Transduction Knowledge Environment. 2006: pl6. PMID 16985238 DOI: 10.1126/Stke.3532006Pl6 |
0.55 |
|
| 2006 |
Hein P, Rochais F, Hoffmann C, Dorsch S, Nikolaev VO, Engelhardt S, Berlot CH, Lohse MJ, Bünemann M. Gs activation is time-limiting in initiating receptor-mediated signaling. The Journal of Biological Chemistry. 281: 33345-51. PMID 16963443 DOI: 10.1074/Jbc.M606713200 |
0.806 |
|
| 2006 |
Nikolaev VO, Hoffmann C, Bünemann M, Lohse MJ, Vilardaga JP. Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer. The Journal of Biological Chemistry. 281: 24506-11. PMID 16787921 DOI: 10.1074/Jbc.M603266200 |
0.807 |
|
| 2006 |
Nikolaev VO, Lohse MJ. Monitoring of cAMP synthesis and degradation in living cells. Physiology (Bethesda, Md.). 21: 86-92. PMID 16565474 DOI: 10.1152/Physiol.00057.2005 |
0.558 |
|
| 2006 |
Nikolaev VO, Gambaryan S, Lohse MJ. Fluorescent sensors for rapid monitoring of intracellular cGMP. Nature Methods. 3: 23-5. PMID 16369548 DOI: 10.1038/Nmeth816 |
0.526 |
|
| 2005 |
Castro M, Nikolaev VO, Palm D, Lohse MJ, Vilardaga JP. Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 16084-9. PMID 16236727 DOI: 10.1073/Pnas.0503942102 |
0.707 |
|
| 2005 |
Landa LR, Harbeck M, Kaihara K, Chepurny O, Kitiphongspattana K, Graf O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. The Journal of Biological Chemistry. 280: 31294-302. PMID 15987680 DOI: 10.1074/Jbc.M505657200 |
0.49 |
|
| 2005 |
Nikolaev VO, Gambaryan S, Engelhardt S, Walter U, Lohse MJ. Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. The Journal of Biological Chemistry. 280: 1716-9. PMID 15557342 DOI: 10.1074/Jbc.C400505200 |
0.687 |
|
| 2005 |
Nikolaev VO, Lohse MJ. Visualization of cAMP in living cells | Visualisierung von cAMP in lebenden zellen Biospektrum. 11: 724-726. |
0.426 |
|
| 2004 |
Nikolaev VO, Bünemann M, Hein L, Hannawacker A, Lohse MJ. Novel single chain cAMP sensors for receptor-induced signal propagation. The Journal of Biological Chemistry. 279: 37215-8. PMID 15231839 DOI: 10.1074/Jbc.C400302200 |
0.749 |
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