| Year |
Citation |
Score |
| 2024 |
King DR, Demirtas M, Tarasov M, Struckman HL, Meng X, Nassal D, Moise N, Miller A, Min D, Soltisz AM, Anne MNK, Alves Dias PA, Wagnon JL, Weinberg SH, Hund TJ, et al. Cardiac-Specific Deletion of Scn8a Mitigates Dravet Syndrome-Associated Sudden Death in Adults. Jacc. Clinical Electrophysiology. PMID 38430092 DOI: 10.1016/j.jacep.2024.01.003 |
0.321 |
|
| 2023 |
Wallace MJ, Malhotra N, Elio Mariángelo JI, Stevens TL, Young LJ, Antwi-Boasiako S, Abdallah D, Takenaka SS, Cavus O, Murphy NP, Han M, Xu X, Mangoni ME, Hund TJ, Roberts JD, et al. Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant. The Journal of Biological Chemistry. 104818. PMID 37182735 DOI: 10.1016/j.jbc.2023.104818 |
0.329 |
|
| 2022 |
Winkle AJ, Nassal DM, Shaheen R, Thomas E, Mohta S, Gratz D, Weinberg SH, Hund TJ. Emerging therapeutic targets for cardiac hypertrophy. Expert Opinion On Therapeutic Targets. 1-12. PMID 35076342 DOI: 10.1080/14728222.2022.2031974 |
0.325 |
|
| 2021 |
Gratz D, Winkle AJ, Weinberg SH, Hund TJ. Statistical Approach to Incorporating Experimental Variability into a Mathematical Model of the Voltage-Gated Na Channel and Human Atrial Action Potential. Cells. 10. PMID 34208565 DOI: 10.3390/cells10061516 |
0.321 |
|
| 2021 |
Nassal D, Yu J, Min D, Lane C, Shaheen R, Gratz D, Hund TJ. Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes. Journal of Cardiovascular Development and Disease. 8. PMID 33946725 DOI: 10.3390/jcdd8050048 |
0.39 |
|
| 2021 |
Cavus O, Williams J, Musa H, El Refaey M, Gratz D, Shaheen R, Schwieterman NA, Koenig S, Antwi-Boasiako S, Young LJ, Xu X, Han M, Wold LE, Hund TJ, Mohler PJ, et al. Giant ankyrin-G regulates cardiac function. The Journal of Biological Chemistry. 100507. PMID 33675749 DOI: 10.1016/j.jbc.2021.100507 |
0.392 |
|
| 2021 |
Dorn LE, Lawrence WR, Petrosino J, Xu X, Hund TJ, Whitson BA, Stratton MS, Janssen PM, Mohler PJ, Schlosser A, Sørensen GL, Accornero F. Microfibrillar-Associated Protein 4 Regulates Stress-Induced Cardiac Remodeling. Circulation Research. PMID 33530700 DOI: 10.1161/CIRCRESAHA.120.317146 |
0.378 |
|
| 2020 |
Comelli M, Meo M, Cervantes DO, Pizzo E, Plosker A, Mohler PJ, Hund TJ, Jacobson JT, Meste O, Rota M. Rhythm Dynamics of the Aging Heart: an Experimental Study Using Conscious, Restrained Mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32886003 DOI: 10.1152/Ajpheart.00379.2020 |
0.383 |
|
| 2020 |
Konstantinidis K, Bezzerides VJ, Lai L, Isbell HM, Wei AC, Wu Y, Viswanathan MC, Blum ID, Granger JM, Heims-Waldron D, Zhang D, Luczak ED, Murphy KR, Lu F, Gratz DH, ... ... Hund TJ, et al. MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII. The Journal of Clinical Investigation. PMID 32749237 DOI: 10.1172/Jci133181 |
0.397 |
|
| 2020 |
Nassal D, Gratz D, Hund TJ. Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart. Frontiers in Pharmacology. 11: 35. PMID 32116711 DOI: 10.3389/Fphar.2020.00035 |
0.38 |
|
| 2020 |
Unudurthi SD, Nassal DM, Patel NJ, Thomas E, Yu J, Pierson CG, Bansal SS, Mohler PJ, Hund TJ. Fibroblast growth factor-inducible 14 mediates macrophage infiltration in heart to promote pressure overload-induced cardiac dysfunction. Life Sciences. 117440. PMID 32070706 DOI: 10.1016/J.Lfs.2020.117440 |
0.377 |
|
| 2020 |
Liu CH, Stevens SR, Teliska LH, Stankewich M, Mohler PJ, Hund TJ, Rasband MN. Nodal β spectrins are required to maintain Na channel clustering and axon integrity. Elife. 9. PMID 32052742 DOI: 10.7554/Elife.52378 |
0.307 |
|
| 2020 |
Liu C, Seo R, Ho TS, Stankewich M, Mohler PJ, Hund TJ, Noebels JL, Rasband MN. Author response: β spectrin-dependent and domain specific mechanisms for Na+ channel clustering Elife. DOI: 10.7554/Elife.56629.Sa2 |
0.308 |
|
| 2020 |
Struckman H, Greer-Short A, Baine S, Mezache L, Phillips A, Gyorke S, Hund T, Veeraraghavan R. The Nanoscale Basis of Atrial Fibrillation: Functional Impact of Disrupting NaV1.5-rich Intercalated Disk Nanodomains. Microscopy and Microanalysis. 1-2. DOI: 10.1017/S1431927620016001 |
0.318 |
|
| 2020 |
Mezache L, Struckman H, Phillips A, Baine S, Greer-Short A, Gyorke S, Radwanski P, Hund TJ, Veeraraghavan R. The Vascular Barrier Regulates Cardiac Nanodomains: Implications for the Genesis of Atrial Fibrillation Biophysical Journal. 118: 463a. DOI: 10.1016/J.Bpj.2019.11.2573 |
0.4 |
|
| 2019 |
Long VP, Bonilla IM, Baine S, Glynn P, Kumar S, Schober K, Mowrey K, Weiss R, Lee NY, Mohler PJ, Györke S, Hund TJ, Fedorov VV, Carnes CA. Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated I. Life Sciences. 117068. PMID 31751583 DOI: 10.1016/J.Lfs.2019.117068 |
0.35 |
|
| 2019 |
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud GE, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, ... ... Hund TJ, et al. Correction: Defining new mechanistic roles for α II spectrin in cardiac function. The Journal of Biological Chemistry. 294: 15557. PMID 31628198 DOI: 10.1074/Jbc.Aac119.011151 |
0.355 |
|
| 2019 |
Greer-Short A, Musa H, Alsina KM, Ni L, Word TA, Reynolds JO, Gratz D, Lane C, El-Refaey M, Unudurthi S, Skaf M, Li N, Fedorov VV, Wehrens XHT, Mohler PJ, ... Hund TJ, et al. Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling and atrial arrhythmia. Heart Rhythm. PMID 31622781 DOI: 10.1016/J.Hrthm.2019.10.016 |
0.407 |
|
| 2019 |
Patel NJ, Nassal DM, Greer-Short AD, Unudurthi SD, Scandling BW, Gratz D, Xu X, Kalyanasundaram A, Fedorov VV, Accornero F, Mohler PJ, Gooch KJ, Hund TJ. βIV-spectrin/STAT3 complex regulates fibroblast phenotype, fibrosis and cardiac function. Jci Insight. PMID 31550236 DOI: 10.1172/Jci.Insight.131046 |
0.413 |
|
| 2019 |
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, ... ... Hund TJ, et al. Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy. The Journal of Clinical Investigation. 130. PMID 31264976 DOI: 10.1172/Jci125538 |
0.4 |
|
| 2019 |
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud GE, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, ... ... Hund TJ, et al. Defining new mechanistic roles for αII spectrin in cardiac function. The Journal of Biological Chemistry. PMID 31064843 DOI: 10.1074/Jbc.Ra119.007714 |
0.495 |
|
| 2019 |
El Refaey M, Musa H, Smith SA, Binkley PF, Bradley E, Hund TJ, Mohler PJ. Response by El Refaey et al to Letter Regarding Article, "Protein Phosphatase 2A Regulates Cardiac Na Channels". Circulation Research. 124: e60-e61. PMID 30973807 DOI: 10.1161/Circresaha.119.314938 |
0.358 |
|
| 2019 |
El Refaey M, Musa H, Murphy NP, Lubbers E, Skaf M, Han M, Cavus O, Koenig SN, Wallace MJ, Gratz D, Bradley E, Alsina KM, Wehrens XH, Hund TJ, Mohler PJ. Protein Phosphatase 2A Regulates Cardiac Na Channels. Circulation Research. PMID 30602331 DOI: 10.1161/Circresaha.118.314350 |
0.429 |
|
| 2019 |
Dorn LE, Lasman L, Chen J, Xu X, Hund TJ, Medvedovic M, Hanna JH, van Berlo JH, Accornero F. The N-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy. Circulation. 139: 533-545. PMID 30586742 DOI: 10.1161/Circulationaha.118.036146 |
0.305 |
|
| 2019 |
Patel NJ, Nassal DM, Scandling BW, Greer-Short AD, Unudurthi SD, Xu X, Mohler PJ, Gooch KJ, Hund TJ. Abstract 844: β
IV
-spectrin Regulates Cardiac Fibroblast Phenotype, Fibrosis, and Cardiac Function Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.844 |
0.413 |
|
| 2019 |
Dorn LE, Lawrence W, Petrosino JM, Xu X, Hund TJ, Schlosser A, Sorensen GL, Accornero F. Abstract 248: Microfibrillar-Associated Protein 4 Regulates Maladaptive Cardiac Remodeling Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.248 |
0.412 |
|
| 2019 |
Unudurthi S, Thomas E, Patel N, Winkle A, Gratz D, Hund T. Abstract 229: TWEAK-Fn14 Axis: A Potential Therapeutic Target for Treating Heart Failure Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.229 |
0.346 |
|
| 2019 |
Struckman HL, Mezache L, Greer-Short A, Phillips A, Hund TJ, Veeraraghavan R. Selective De-Adhesion Within Intercalated Disk Nanodomains Prompts Proarrhythmic Conduction Slowing in the Heart Biophysical Journal. 116: 311a-312a. DOI: 10.1016/J.Bpj.2018.11.1689 |
0.351 |
|
| 2018 |
Makara MA, Curran J, Lubbers ER, Murphy NP, Little SC, Musa H, Smith SA, Unudurthi SD, Rajaram MVS, Janssen PML, Boyden PA, Bradley EA, Hund TJ, Mohler PJ. Novel Mechanistic Roles for Ankyrin-G in Cardiac Remodeling and Heart Failure. Jacc. Basic to Translational Science. 3: 675-689. PMID 30456339 DOI: 10.1016/J.Jacbts.2018.07.008 |
0.415 |
|
| 2018 |
Yoo S, Aistrup G, Shiferaw Y, Ng J, Mohler PJ, Hund TJ, Waugh T, Browne S, Gussak G, Gilani M, Knight BP, Passman R, Goldberger JJ, Wasserstrom JA, Arora R. Oxidative stress creates a unique, CaMKII-mediated substrate for atrial fibrillation in heart failure. Jci Insight. 3. PMID 30385719 DOI: 10.1172/Jci.Insight.120728 |
0.411 |
|
| 2018 |
Unudurthi SD, Nassal DM, Greer-Short A, Patel NJ, Howard T, Xu X, Onal B, Satroplus T, Hong DY, Lane CM, Dalic A, Koenig SN, Lehnig AC, Baer LA, Musa H, ... ... Hund TJ, et al. βIV-spectrin regulates STAT3 targeting to tune cardiac response to pressure overload. The Journal of Clinical Investigation. PMID 30226828 DOI: 10.1172/Jci99245 |
0.471 |
|
| 2018 |
Howard T, Greer-Short A, Satroplus T, Patel N, Nassal D, Mohler PJ, Hund TJ. CaMKII-dependent late sodium current increases electrical dispersion and arrhythmia in ischemia/reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29932771 DOI: 10.1152/Ajpheart.00197.2018 |
0.413 |
|
| 2018 |
Gratz D, Onal B, Dalic A, Hund TJ. Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study Frontiers in Physics. 6. DOI: 10.3389/Fphy.2018.00063 |
0.398 |
|
| 2018 |
Greer-Short A, Hund T, Veeraraghavan R. Structural Changes in Sodium Channel-Rich Nanodomains Contribute to the Progression of Atrial Fibrillation Microscopy and Microanalysis. 24: 1268-1269. DOI: 10.1017/S1431927618006827 |
0.355 |
|
| 2017 |
Greer-Short A, Hund TJ. Editorial commentary: Mathematical modeling as a tool to elucidate fundamental principles in cardiac electrophysiology. Trends in Cardiovascular Medicine. PMID 29269287 DOI: 10.1016/J.Tcm.2017.12.001 |
0.378 |
|
| 2017 |
Unudurthi SD, Greer-Short A, Patel N, Nassal D, Hund TJ. Spectrin-based pathways underlying electrical and mechanical dysfunction in cardiac disease. Expert Review of Cardiovascular Therapy. PMID 29257730 DOI: 10.1080/14779072.2018.1418664 |
0.421 |
|
| 2017 |
Mohler PJ, Hund TJ. Novel Pathways for Regulation of Sinoatrial Node Plasticity and Heart Rate. Circulation Research. 121: 1027-1028. PMID 29025753 DOI: 10.1161/Circresaha.117.311922 |
0.454 |
|
| 2017 |
Onal B, Gratz D, Hund TJ. Ca(2+)/calmodulin kinase II-dependent regulation of atrial myocyte late Na+ current, Ca(2+) cycling and excitability: a mathematical modeling study. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00185.2017. PMID 28842436 DOI: 10.1152/Ajpheart.00185.2017 |
0.349 |
|
| 2016 |
Onal B, Gratz D, Hund T. LongQt: A cardiac electrophysiology simulation platform. Methodsx. 3: 589-599. PMID 27942465 DOI: 10.1016/J.Mex.2016.11.002 |
0.398 |
|
| 2016 |
Radwański PB, Ho HT, Veeraraghavan R, Brunello L, Liu B, Belevych AE, Unudurthi SD, Makara MA, Priori SG, Volpe P, Armoundas AA, Dillmann WH, Knollmann BC, Mohler PJ, Hund TJ, et al. Neuronal Na(+) Channels Are Integral Components of Pro-arrhythmic Na(+)/Ca(2+) Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-adrenergic Stimulation. Jacc. Basic to Translational Science. 1: 251-266. PMID 27747307 DOI: 10.1016/J.Jacbts.2016.04.004 |
0.446 |
|
| 2016 |
Hund TJ, Mohler PJ. Atrial-specific pathways for control of intracellular signaling and myocyte function. The Journal of Clinical Investigation. PMID 27643440 DOI: 10.1172/Jci90348 |
0.407 |
|
| 2016 |
Musa H, Murphy NP, Curran J, Higgins JD, Webb TR, Makara MA, Wright P, Lancione PJ, Lubbers ER, Healy JA, Smith SA, Bennett V, Hund TJ, Kline CF, Mohler PJ. Common human ANK2 variant confers in vivo arrhythmia phenotypes. Heart Rhythm : the Official Journal of the Heart Rhythm Society. PMID 27298202 DOI: 10.1016/J.Hrthm.2016.06.012 |
0.325 |
|
| 2016 |
Smith S, Hughes L, Kline CF, Kempton A, Dorn L, Curran J, Makara M, Webb T, Wright P, Voigt N, Binkley PF, Janssen PM, Kilic A, Carnes CA, Dobrev D, ... ... Hund TJ, et al. Dysfunction of the βII spectrin-based pathway in human heart failure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00875.2015. PMID 27106045 DOI: 10.1152/Ajpheart.00875.2015 |
0.458 |
|
| 2016 |
Unudurthi SD, Wu X, Qian L, Amari F, Onal B, Li N, Makara MA, Smith SA, Snyder J, Fedorov VV, Coppola V, Anderson ME, Mohler PJ, Hund TJ. Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability. Journal of the American Heart Association. 5. PMID 27098968 DOI: 10.1161/Jaha.115.002865 |
0.411 |
|
| 2016 |
Radwański PB, Ho H, Liu B, Belevych A, Armoundas A, Dillmann W, Knollmann B, Mohler P, Hund T, Györke S. Catecholaminergic Stimulation of Neuronal Na+ Channels Accounts for Triggered Arrhythmia Mechanism in CPVT Biophysical Journal. 110: 435a. DOI: 10.1016/J.Bpj.2015.11.2348 |
0.403 |
|
| 2015 |
Liu B, Ho HT, Brunello L, Unudurthi SD, Lou Q, Belevych AE, Qian L, Kim DH, Cho C, Janssen PM, Hund TJ, Knollmann BC, Kranias EG, Györke S. Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT. Cardiovascular Research. PMID 26410369 DOI: 10.1093/Cvr/Cvv222 |
0.412 |
|
| 2015 |
Musa H, Kline CF, Sturm AC, Murphy N, Adelman S, Wang C, Yan H, Johnson BL, Csepe TA, Kilic A, Higgins RS, Janssen PM, Fedorov VV, Weiss R, Salazar C, ... Hund TJ, et al. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 112: 12528-33. PMID 26392562 DOI: 10.1073/Pnas.1516430112 |
0.448 |
|
| 2015 |
Little SC, Curran J, Makara MA, Kline CF, Ho HT, Xu Z, Wu X, Polina I, Musa H, Meadows AM, Carnes CA, Biesiadecki BJ, Davis JP, Weisleder N, Györke S, ... ... Hund TJ, et al. Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart. Science Signaling. 8: ra72. PMID 26198358 DOI: 10.1126/Scisignal.Aaa5876 |
0.466 |
|
| 2015 |
Glynn P, Musa H, Wu X, Unudurthi SD, Little S, Qian L, Wright PJ, Radwanski PB, Gyorke S, Mohler PJ, Hund TJ. Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function in vivo. Circulation. PMID 26187182 DOI: 10.1161/Circulationaha.114.015218 |
0.432 |
|
| 2015 |
Sturm AC, Kline CF, Glynn P, Johnson BL, Curran J, Kilic A, Higgins RS, Binkley PF, Janssen PM, Weiss R, Raman SV, Fowler SJ, Priori SG, Hund TJ, Carnes CA, et al. Use of whole exome sequencing for the identification of Ito-based arrhythmia mechanism and therapy. Journal of the American Heart Association. 4. PMID 26015324 DOI: 10.1161/Jaha.114.001762 |
0.385 |
|
| 2015 |
Curran J, Musa H, Kline CF, Makara MA, Little SC, Higgins JD, Hund TJ, Band H, Mohler PJ. Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. The Journal of Biological Chemistry. 290: 12210-21. PMID 25825486 DOI: 10.1074/Jbc.M115.646893 |
0.5 |
|
| 2015 |
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428 |
0.401 |
|
| 2015 |
Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, ... ... Hund TJ, et al. Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia. Circulation. 131: 695-708. PMID 25632041 DOI: 10.1161/Circulationaha.114.013708 |
0.447 |
|
| 2015 |
Hund TJ, Mohler PJ. Role of CaMKII in cardiac arrhythmias. Trends in Cardiovascular Medicine. 25: 392-397. PMID 25577293 DOI: 10.1016/J.Tcm.2014.12.001 |
0.465 |
|
| 2015 |
Radwa?ski PB, Brunello L, Veeraraghavan R, Ho HT, Lou Q, Makara MA, Belevych AE, Anghelescu M, Priori SG, Volpe P, Hund TJ, Janssen PM, Mohler PJ, Bridge JH, Poelzing S, et al. Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release. Cardiovascular Research. 106: 143-52. PMID 25538156 DOI: 10.1093/Cvr/Cvu262 |
0.425 |
|
| 2014 |
Unudurthi SD, Wolf RM, Hund TJ. Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking. Frontiers in Physiology. 5: 446. PMID 25505419 DOI: 10.3389/Fphys.2014.00446 |
0.407 |
|
| 2014 |
Makara MA, Curran J, Little SC, Musa H, Polina I, Smith SA, Wright PJ, Unudurthi SD, Snyder J, Bennett V, Hund TJ, Mohler PJ. Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo. Circulation Research. 115: 929-38. PMID 25239140 DOI: 10.1161/Circresaha.115.305154 |
0.501 |
|
| 2014 |
Hund TJ, Mohler PJ. Nav channel complex heterogeneity: new targets for the treatment of arrhythmia? Circulation. 130: 132-4. PMID 24895456 DOI: 10.1161/Circulationaha.114.010867 |
0.454 |
|
| 2014 |
Dybkova N, Wagner S, Backs J, Hund TJ, Mohler PJ, Sowa T, Nikolaev VO, Maier LS. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77. PMID 24812278 DOI: 10.1093/Cvr/Cvu120 |
0.428 |
|
| 2014 |
Curran J, Makara MA, Little SC, Musa H, Liu B, Wu X, Polina I, Alecusan JS, Wright P, Li J, Billman GE, Boyden PA, Gyorke S, Band H, Hund TJ, et al. EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology. Circulation Research. 115: 68-78. PMID 24759929 DOI: 10.1161/Circresaha.115.304149 |
0.419 |
|
| 2014 |
Vreeker A, van Stuijvenberg L, Hund TJ, Mohler PJ, Nikkels PG, van Veen TA. Assembly of the cardiac intercalated disk during pre- and postnatal development of the human heart. Plos One. 9: e94722. PMID 24733085 DOI: 10.1371/Journal.Pone.0094722 |
0.454 |
|
| 2014 |
Onal B, Unudurthi SD, Hund TJ. Modeling CaMKII in cardiac physiology: from molecule to tissue. Frontiers in Pharmacology. 5: 9. PMID 24550832 DOI: 10.3389/Fphar.2014.00009 |
0.488 |
|
| 2014 |
Glynn P, Onal B, Hund TJ. Cycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics. Plos One. 9: e89049. PMID 24533169 DOI: 10.1371/Journal.Pone.0089049 |
0.323 |
|
| 2014 |
Hund TJ, Snyder JS, Wu X, Glynn P, Koval OM, Onal B, Leymaster ND, Unudurthi SD, Curran J, Camardo C, Wright PJ, Binkley PF, Anderson ME, Mohler PJ. β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart. Cardiovascular Research. 102: 166-75. PMID 24445605 DOI: 10.1093/Cvr/Cvu008 |
0.443 |
|
| 2014 |
Kline CF, Scott J, Curran J, Hund TJ, Mohler PJ. Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting. The Journal of Biological Chemistry. 289: 5285-95. PMID 24394417 DOI: 10.1074/Jbc.M113.523639 |
0.36 |
|
| 2014 |
Ho HT, Liu B, Snyder JS, Lou Q, Brundage EA, Velez-Cortes F, Wang H, Ziolo MT, Anderson ME, Sen CK, Wehrens XH, Fedorov VV, Biesiadecki BJ, Hund TJ, Györke S. Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides. Cardiovascular Research. 101: 165-74. PMID 24104877 DOI: 10.1093/Cvr/Cvt233 |
0.378 |
|
| 2014 |
Curran J, Little S, Makara M, Wu X, Polina I, Wright PJ, Liu B, Gyorke S, Hund TJ, Mohler PJ. EHD3 Mediates Integral Membrane Protein Trafficking and Maintain Electrical Excitability and Adrenergic Responsiveness in the Heart Biophysical Journal. 106: 526a-527a. DOI: 10.1016/J.Bpj.2013.11.2938 |
0.465 |
|
| 2014 |
Hund TJ, Smith SA, Makara MA, Mohler PJ. Cellular and Molecular Pathobiology of the Cardiac Conduction System Cellular and Molecular Pathobiology of Cardiovascular Disease. 121-134. DOI: 10.1016/B978-0-12-405206-2.00007-7 |
0.301 |
|
| 2013 |
Dun W, Lowe JS, Wright P, Hund TJ, Mohler PJ, Boyden PA. Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart. Plos One. 8: e78087. PMID 24155982 DOI: 10.1371/Journal.Pone.0078087 |
0.418 |
|
| 2013 |
Kline CF, Wright PJ, Koval OM, Zmuda EJ, Johnson BL, Anderson ME, Hai T, Hund TJ, Mohler PJ. βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 17576-81. PMID 24101510 DOI: 10.1073/Pnas.1314195110 |
0.386 |
|
| 2013 |
Toischer K, Hartmann N, Wagner S, Fischer TH, Herting J, Danner BC, Sag CM, Hund TJ, Mohler PJ, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S. Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease. Journal of Molecular and Cellular Cardiology. 61: 111-22. PMID 23570977 DOI: 10.1016/J.Yjmcc.2013.03.021 |
0.45 |
|
| 2013 |
Wolf RM, Glynn P, Hashemi S, Zarei K, Mitchell CC, Anderson ME, Mohler PJ, Hund TJ. Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1253-66. PMID 23436330 DOI: 10.1152/Ajpheart.00734.2012 |
0.433 |
|
| 2013 |
Luo M, Guan X, Luczak ED, Lang D, Kutschke W, Gao Z, Yang J, Glynn P, Sossalla S, Swaminathan PD, Weiss RM, Yang B, Rokita AG, Maier LS, Efimov IR, ... Hund TJ, et al. Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. The Journal of Clinical Investigation. 123: 1262-74. PMID 23426181 DOI: 10.1172/Jci65268 |
0.326 |
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| 2013 |
DeGrande ST, Little SC, Nixon DJ, Wright P, Snyder J, Dun W, Murphy N, Kilic A, Higgins R, Binkley PF, Boyden PA, Carnes CA, Anderson ME, Hund TJ, Mohler PJ. Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart. The Journal of Biological Chemistry. 288: 1032-46. PMID 23204520 DOI: 10.1074/Jbc.M112.426957 |
0.447 |
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| 2013 |
Gao Z, Rasmussen TP, Li Y, Kutschke W, Koval OM, Wu Y, Wu Y, Hall DD, Joiner ML, Wu XQ, Swaminathan PD, Purohit A, Zimmerman K, Weiss RM, Philipson KD, ... ... Hund TJ, et al. Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circulation Research. 112: 309-17. PMID 23192947 DOI: 10.1161/Circresaha.111.300193 |
0.41 |
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| 2013 |
Noorman M, Hakim S, Kessler E, Groeneweg JA, Cox MG, Asimaki A, van Rijen HV, van Stuijvenberg L, Chkourko H, van der Heyden MA, Vos MA, de Jonge N, van der Smagt JJ, Dooijes D, Vink A, ... ... Hund TJ, et al. Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 412-9. PMID 23178689 DOI: 10.1016/J.Hrthm.2012.11.018 |
0.429 |
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| 2013 |
Hund TJ, Mohler PJ. Biophysics of Normal and Abnormal Cardiac Sodium Channel Function Cardiac Electrophysiology: From Cell to Bedside: Sixth Edition. 95-101. DOI: 10.1016/B978-1-4557-2856-5.00009-1 |
0.324 |
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| 2012 |
DeGrande S, Nixon D, Koval O, Curran JW, Wright P, Wang Q, Kashef F, Chiang D, Li N, Wehrens XH, Anderson ME, Hund TJ, Mohler PJ. CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 2034-41. PMID 23059182 DOI: 10.1016/J.Hrthm.2012.08.026 |
0.374 |
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| 2012 |
Koval OM, Snyder JS, Wolf RM, Pavlovicz RE, Glynn P, Curran J, Leymaster ND, Dun W, Wright PJ, Cardona N, Qian L, Mitchell CC, Boyden PA, Binkley PF, Li C, ... ... Hund TJ, et al. Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease. Circulation. 126: 2084-94. PMID 23008441 DOI: 10.1161/Circulationaha.112.105320 |
0.507 |
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| 2012 |
Kashef F, Li J, Wright P, Snyder J, Suliman F, Kilic A, Higgins RS, Anderson ME, Binkley PF, Hund TJ, Mohler PJ. Ankyrin-B protein in heart failure: identification of a new component of metazoan cardioprotection. The Journal of Biological Chemistry. 287: 30268-81. PMID 22778271 DOI: 10.1074/Jbc.M112.368415 |
0.428 |
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| 2012 |
Cerrone M, Noorman M, Lin X, Chkourko H, Liang FX, van der Nagel R, Hund T, Birchmeier W, Mohler P, van Veen TA, van Rijen HV, Delmar M. Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency. Cardiovascular Research. 95: 460-8. PMID 22764151 DOI: 10.1093/Cvr/Cvs218 |
0.442 |
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| 2012 |
Swaminathan PD, Purohit A, Hund TJ, Anderson ME. Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias. Circulation Research. 110: 1661-77. PMID 22679140 DOI: 10.1161/Circresaha.111.243956 |
0.478 |
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| 2012 |
Smith S, Curran J, Hund TJ, Mohler PJ. Defects in cytoskeletal signaling pathways, arrhythmia, and sudden cardiac death. Frontiers in Physiology. 3: 122. PMID 22586405 DOI: 10.3389/Fphys.2012.00122 |
0.419 |
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| 2012 |
Gudmundsson H, Curran J, Kashef F, Snyder JS, Smith SA, Vargas-Pinto P, Bonilla IM, Weiss RM, Anderson ME, Binkley P, Felder RB, Carnes CA, Band H, Hund TJ, Mohler PJ. Differential regulation of EHD3 in human and mammalian heart failure. Journal of Molecular and Cellular Cardiology. 52: 1183-90. PMID 22406195 DOI: 10.1016/J.Yjmcc.2012.02.008 |
0.455 |
|
| 2012 |
Jansen JA, Noorman M, Musa H, Stein M, de Jong S, van der Nagel R, Hund TJ, Mohler PJ, Vos MA, van Veen TA, de Bakker JM, Delmar M, van Rijen HV. Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 600-7. PMID 22100711 DOI: 10.1016/J.Hrthm.2011.11.025 |
0.359 |
|
| 2011 |
Besse IM, Mitchell CC, Hund TJ, Shibata EF. A computational investigation of cardiac caveolae as a source of persistent sodium current. Frontiers in Physiology. 2: 87. PMID 22144962 DOI: 10.3389/Fphys.2011.00087 |
0.425 |
|
| 2011 |
Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, et al. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation. 124: 1212-22. PMID 21859974 DOI: 10.1161/Circulationaha.111.023986 |
0.409 |
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| 2011 |
Mohler PJ, Hund TJ. Membrane-select regulation of cardiac Na(v) channel isoforms. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 1931-2. PMID 21835149 DOI: 10.1016/J.Hrthm.2011.08.002 |
0.443 |
|
| 2011 |
Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Luczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, ... ... Hund TJ, et al. Oxidized CaMKII causes cardiac sinus node dysfunction in mice. The Journal of Clinical Investigation. 121: 3277-88. PMID 21785215 DOI: 10.1172/Jci57833 |
0.375 |
|
| 2011 |
Gao Z, Singh MV, Hall DD, Koval OM, Luczak ED, Joiner ML, Chen B, Wu Y, Chaudhary AK, Martins JB, Hund TJ, Mohler PJ, Song LS, Anderson ME. Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II. Circulation. Arrhythmia and Electrophysiology. 4: 379-87. PMID 21406683 DOI: 10.1161/Circep.110.961771 |
0.407 |
|
| 2011 |
Hund TJ, Mohler PJ. Differential roles for SUR subunits in KATP channel membrane targeting and regulation. American Journal of Physiology. Heart and Circulatory Physiology. 300: H33-5. PMID 21057044 DOI: 10.1152/Ajpheart.01088.2010 |
0.368 |
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| 2011 |
Mohler PJ, Hund TJ. Role of CaMKII in cardiovascular health, disease, and arrhythmia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 142-4. PMID 20673813 DOI: 10.1016/J.Hrthm.2010.07.029 |
0.453 |
|
| 2010 |
Hund TJ, Koval OM, Li J, Wright PJ, Qian L, Snyder JS, Gudmundsson H, Kline CF, Davidson NP, Cardona N, Rasband MN, Anderson ME, Mohler PJ. A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice. The Journal of Clinical Investigation. 120: 3508-19. PMID 20877009 DOI: 10.1172/Jci43621 |
0.455 |
|
| 2010 |
Wolf RM, Mitchell CC, Christensen MD, Mohler PJ, Hund TJ. Defining new insight into atypical arrhythmia: a computational model of ankyrin-B syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1505-14. PMID 20729400 DOI: 10.1152/Ajpheart.00503.2010 |
0.467 |
|
| 2010 |
Li J, Kline CF, Hund TJ, Anderson ME, Mohler PJ. Ankyrin-B regulates Kir6.2 membrane expression and function in heart. The Journal of Biological Chemistry. 285: 28723-30. PMID 20610380 DOI: 10.1074/Jbc.M110.147868 |
0.451 |
|
| 2010 |
Gudmundsson H, Hund TJ, Wright PJ, Kline CF, Snyder JS, Qian L, Koval OM, Cunha SR, George M, Rainey MA, Kashef FE, Dun W, Boyden PA, Anderson ME, Band H, et al. EH domain proteins regulate cardiac membrane protein targeting. Circulation Research. 107: 84-95. PMID 20489164 DOI: 10.1161/Circresaha.110.216713 |
0.4 |
|
| 2010 |
Koval OM, Guan X, Wu Y, Joiner ML, Gao Z, Chen B, Grumbach IM, Luczak ED, Colbran RJ, Song LS, Hund TJ, Mohler PJ, Anderson ME. CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations. Proceedings of the National Academy of Sciences of the United States of America. 107: 4996-5000. PMID 20194790 DOI: 10.1073/Pnas.0913760107 |
0.344 |
|
| 2010 |
Hund TJ, Mohler PJ. Cardiac spectrins: alternative splicing encodes functional diversity. Journal of Molecular and Cellular Cardiology. 48: 1031-2. PMID 20144617 DOI: 10.1016/J.Yjmcc.2010.02.002 |
0.434 |
|
| 2010 |
Kline CF, Hund TJ, Mohler PJ. Ankyrin regulates KATP channel membrane trafficking and gating in excitable cells. Channels (Austin, Tex.). 4: 55-7. PMID 19901534 DOI: 10.4161/Chan.4.1.10362 |
0.343 |
|
| 2009 |
Christensen MD, Dun W, Boyden PA, Anderson ME, Mohler PJ, Hund TJ. Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis. Plos Computational Biology. 5: e1000583. PMID 19997488 DOI: 10.1371/Journal.Pcbi.1000583 |
0.426 |
|
| 2009 |
Kline CF, Kurata HT, Hund TJ, Cunha SR, Koval OM, Wright PJ, Christensen M, Anderson ME, Nichols CG, Mohler PJ. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 16669-74. PMID 19805355 DOI: 10.1073/Pnas.0907138106 |
0.372 |
|
| 2009 |
Hashemi SM, Hund TJ, Mohler PJ. Cardiac ankyrins in health and disease. Journal of Molecular and Cellular Cardiology. 47: 203-9. PMID 19394342 DOI: 10.1016/J.Yjmcc.2009.04.010 |
0.489 |
|
| 2009 |
Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME. Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proceedings of the National Academy of Sciences of the United States of America. 106: 5972-7. PMID 19276108 DOI: 10.1073/Pnas.0806422106 |
0.405 |
|
| 2009 |
Decker KF, Heijman J, Silva JR, Hund TJ, Rudy Y. Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1017-26. PMID 19168720 DOI: 10.1152/Ajpheart.01216.2008 |
0.39 |
|
| 2009 |
Hund TJ, Wright PJ, Dun W, Snyder JS, Boyden PA, Mohler PJ. Regulation of the ankyrin-B-based targeting pathway following myocardial infarction. Cardiovascular Research. 81: 742-9. PMID 19074823 DOI: 10.1093/Cvr/Cvn348 |
0.403 |
|
| 2008 |
Hund TJ, Mohler PJ. Ankyrin-based targeting pathway regulates human sinoatrial node automaticity. Channels (Austin, Tex.). 2: 404-6. PMID 19098452 DOI: 10.4161/Chan.2.6.7220 |
0.434 |
|
| 2008 |
Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, Anderson ME. Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation. 118: 2225-34. PMID 19001023 DOI: 10.1161/Circulationaha.108.788067 |
0.355 |
|
| 2008 |
Le Scouarnec S, Bhasin N, Vieyres C, Hund TJ, Cunha SR, Koval O, Marionneau C, Chen B, Wu Y, Demolombe S, Song LS, Le Marec H, Probst V, Schott JJ, Anderson ME, et al. Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 15617-22. PMID 18832177 DOI: 10.1073/Pnas.0805500105 |
0.408 |
|
| 2008 |
Hund TJ, Decker KF, Kanter E, Mohler PJ, Boyden PA, Schuessler RB, Yamada KA, Rudy Y. Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling. Journal of Molecular and Cellular Cardiology. 45: 420-8. PMID 18639555 DOI: 10.1016/J.Yjmcc.2008.06.007 |
0.469 |
|
| 2008 |
Hund TJ, Ziman AP, Lederer WJ, Mohler PJ. The cardiac IP3 receptor: uncovering the role of "the other" calcium-release channel. Journal of Molecular and Cellular Cardiology. 45: 159-61. PMID 18598702 DOI: 10.1016/J.Yjmcc.2008.06.001 |
0.384 |
|
| 2008 |
Lowe JS, Palygin O, Bhasin N, Hund TJ, Boyden PA, Shibata E, Anderson ME, Mohler PJ. Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway. The Journal of Cell Biology. 180: 173-86. PMID 18180363 DOI: 10.1083/Jcb.200710107 |
0.411 |
|
| 2007 |
Hund TJ, Lerner DL, Yamada KA, Schuessler RB, Saffitz JE. Protein kinase Cepsilon mediates salutary effects on electrical coupling induced by ischemic preconditioning. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 1183-93. PMID 17765619 DOI: 10.1016/J.Hrthm.2007.05.030 |
0.384 |
|
| 2006 |
Hund TJ, Rudy Y. A role for calcium/calmodulin-dependent protein kinase II in cardiac disease and arrhythmia Handbook of Experimental Pharmacology. 171: 201-220. PMID 16610345 DOI: 10.1007/3-540-29715-4_7 |
0.406 |
|
| 2004 |
Hund TJ, Rudy Y. Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model. Circulation. 110: 3168-74. PMID 15505083 DOI: 10.1161/01.Cir.0000147231.69595.D3 |
0.377 |
|
| 2003 |
Hund TJ, Rudy Y. Calcium Regulation and Cellular Electrophysiology Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 7-8. |
0.332 |
|
| 2001 |
Hund TJ, Kucera JP, Otani NF, Rudy Y. Ionic charge conservation and long-term steady state in the Luo-Rudy dynamic cell model Biophysical Journal. 81: 3324-3331. PMID 11720995 DOI: 10.1016/S0006-3495(01)75965-6 |
0.312 |
|
| 2000 |
Hund TJ, Rudy Y. Determinants of excitability in cardiac myocytes: Mechanistic investigation of memory effect Biophysical Journal. 79: 3095-3104. PMID 11106615 DOI: 10.1016/S0006-3495(00)76544-1 |
0.35 |
|
| 2000 |
Hund TJ, Otani NF, Rudy Y. Dynamics of action potential head-tail interaction during reentry in cardiac tissue: Ionic mechanisms American Journal of Physiology - Heart and Circulatory Physiology. 279: H1869-H1879. PMID 11009475 DOI: 10.1152/Ajpheart.2000.279.4.H1869 |
0.31 |
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