Cun Yu Wang, D.D.S., Ph.D. - Publications

Affiliations: 
Bioengineering University of California, Los Angeles, Los Angeles, CA 

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Year Citation  Score
2020 Jia L, Zhang W, Wang CY. BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse. Cell Stem Cell. PMID 32697949 DOI: 10.1016/J.Stem.2020.06.022  0.309
2019 Koo JH, Plouffe SW, Meng Z, Lee DH, Yang D, Lim DS, Wang CY, Guan KL. Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth. Genes & Development. PMID 31831627 DOI: 10.1101/Gad.331546.119  0.37
2019 Li J, Yu B, Deng P, Cheng Y, Yu Y, Kevork K, Ramadoss S, Ding X, Li X, Wang CY. Author Correction: KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling. Nature Communications. 10: 5020. PMID 31685815 DOI: 10.1038/S41467-019-12878-Z  0.419
2019 Jin SS, He DQ, Luo D, Wang Y, Yu M, Guan B, Fu Y, Li ZX, Zhang T, Zhou YH, Wang CY, Liu Y. A Biomimetic Hierarchical Nanointerface Orchestrates Macrophage Polarization and Mesenchymal Stem Cell Recruitment to Promote Endogenous Bone Regeneration. Acs Nano. PMID 31125522 DOI: 10.1021/Acsnano.9B00489  0.327
2019 Arai A, Kim S, Goldshteyn V, Kim T, Park NH, Wang CY, Kim R. Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31074883 DOI: 10.1002/Jbmr.3756  0.36
2018 Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, ... ... Wang CY, et al. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. PMID 30135582 DOI: 10.1038/S41586-018-0444-0  0.356
2018 Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, Luo X, Hong C, Lin J, Wang CY. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. PMID 30017591 DOI: 10.1016/J.Stem.2018.06.009  0.434
2017 Zhou CC, Xiong QC, Zhu XX, Du W, Deng P, Li XB, Jiang YZ, Zou SJ, Wang CY, Yuan Q. AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs. Bone Research. 5: 17044. PMID 28955517 DOI: 10.1038/Boneres.2017.44  0.395
2017 Yu Y, Deng P, Yu B, Szymanski JM, Aghaloo T, Hong C, Wang CY. Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3. Stem Cell Reports. PMID 28826853 DOI: 10.1016/J.Stemcr.2017.07.016  0.435
2017 Li J, Yu B, Deng P, Cheng Y, Yu Y, Kevork K, Ramadoss S, Ding X, Li X, Wang CY. KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling. Nature Communications. 8: 15146. PMID 28440295 DOI: 10.1038/Ncomms15146  0.453
2017 Ding PH, Darveau RP, Wang CY, Jin L. 3LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes. Plos One. 12: e0173223. PMID 28384159 DOI: 10.1371/Journal.Pone.0173223  0.309
2017 Chen D, Wu M, Li Y, Chang I, Yuan Q, Ekimyan-Salvo M, Deng P, Yu B, Yu Y, Dong J, Szymanski JM, Ramadoss S, Li J, Wang CY. Targeting BMI1(+) Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma. Cell Stem Cell. PMID 28285905 DOI: 10.1016/J.Stem.2017.02.003  0.409
2016 Cheng Y, Wang Y, Li J, Chang I, Wang CY. A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival. Oncotarget. PMID 28030848 DOI: 10.18632/Oncotarget.14081  0.363
2016 Kang MK, Mehrazarin S, Park NH, Wang CY. Epigenetic gene regulation by histone demethylases: Emerging role in oncogenesis and inflammation. Oral Diseases. PMID 27514027 DOI: 10.1111/Odi.12569  0.338
2016 Chang I, Wang CY. Inhibition of HDAC6 Enhances Bortezomib-induced Apoptosis in HNSCC by Reducing Autophagy. The Journal of Biological Chemistry. PMID 27369083 DOI: 10.1074/Jbc.M116.717793  0.356
2016 Yu B, Wang CY. Osteoporosis: The Result of an 'Aged' Bone Microenvironment. Trends in Molecular Medicine. PMID 27354328 DOI: 10.1016/J.Molmed.2016.06.002  0.393
2016 Hoang M, Kim JJ, Kim Y, Tong E, Trammell B, Liu Y, Shi S, Lee CR, Hong C, Wang CY, Kim Y. Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells. Stem Cell Research. 17: 111-121. PMID 27286573 DOI: 10.1016/J.Scr.2016.05.021  0.328
2016 Deng P, Zhou C, Alvarez R, Hong C, Wang CY. Inhibition of IKK/NF-κB Signaling Enhances Differentiation of Mesenchymal Stromal Cells from Human Embryonic Stem Cells. Stem Cell Reports. PMID 26972683 DOI: 10.1016/J.Stemcr.2016.02.006  0.39
2016 Fan J, Im CS, Guo M, Cui ZK, Fartash A, Kim S, Patel N, Bezouglaia O, Wu BM, Wang CY, Aghaloo TL, Lee M. Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists. Stem Cells Translational Medicine. PMID 26956209 DOI: 10.5966/Sctm.2015-0249  0.384
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Wang C, ... Wang CY, ... Wang C, ... Wang C, ... Wang C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.68
2015 Deng P, Chen QM, Hong C, Wang CY. Histone methyltransferases and demethylases: regulators in balancing osteogenic and adipogenic differentiation of mesenchymal stem cells. International Journal of Oral Science. 7: 197-204. PMID 26674421 DOI: 10.1038/Ijos.2015.41  0.329
2015 Pacios S, Xiao W, Mattos M, Lim J, Tarapore RS, Alsadun S, Yu B, Wang CY, Graves DT. Osteoblast Lineage Cells Play an Essential Role in Periodontal Bone Loss Through Activation of Nuclear Factor-Kappa B. Scientific Reports. 5: 16694. PMID 26666569 DOI: 10.1038/Srep16694  0.454
2015 Lee HL, Yu B, Deng P, Wang CY, Hong C. TGF-β-Induced KDM4B Promotes Chondrogenic Differentiation of Human MSCs. Stem Cells (Dayton, Ohio). PMID 26485430 DOI: 10.1002/Stem.2231  0.45
2015 Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, Graves DT, Park NH, Wang CY. Addendum: Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nature Medicine. 21: 1101. PMID 26340120 DOI: 10.1038/Nm0915-1101  0.416
2015 Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Alternative Wnt Signaling Activates YAP/TAZ. Cell. 162: 780-94. PMID 26276632 DOI: 10.1016/J.Cell.2015.07.013  0.452
2015 Tarapore RS, Lim J, Tian C, Pacios S, Xiao W, Reid D, Guan H, Mattos M, Yu B, Wang CY, Graves DT. NF-kappaB Has a Direct Role in Inhibiting Bmp and Wnt Induced Matrix Protein Expression. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26179215 DOI: 10.1002/Jbmr.2592  0.461
2015 Tang ED, Wang CY. Single amino acid change in STING leads to constitutive active signaling. Plos One. 10: e0120090. PMID 25790474 DOI: 10.1371/Journal.Pone.0120090  0.317
2015 Tang ED, Wang CY. YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation. Cellular Signalling. 27: 836-40. PMID 25636199 DOI: 10.1016/J.Cellsig.2015.01.011  0.375
2014 Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, Graves DT, Park NH, Wang CY. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nature Medicine. 20: 1009-17. PMID 25108526 DOI: 10.1038/Nm.3586  0.449
2014 Huang K, Wu Z, Liu Z, Hu G, Yu J, Chang KH, Kim KP, Le T, Faull KF, Rao N, Gennery A, Xue Z, Wang CY, Pellegrini M, Fan G. Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Human Molecular Genetics. 23: 6448-57. PMID 25027325 DOI: 10.1093/Hmg/Ddu365  0.343
2014 Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, et al. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 25: 822-30. PMID 24882516 DOI: 10.1016/J.Ccr.2014.04.017  0.334
2013 Li J, Chen X, Ding X, Cheng Y, Zhao B, Lai ZC, Al Hezaimi K, Hakem R, Guan KL, Wang CY. LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction. Cell Reports. 5: 1650-63. PMID 24360964 DOI: 10.1016/J.Celrep.2013.11.037  0.365
2013 Xu J, Yu B, Hong C, Wang CY. KDM6B epigenetically regulates odontogenic differentiation of dental mesenchymal stem cells. International Journal of Oral Science. 5: 200-5. PMID 24158144 DOI: 10.1038/Ijos.2013.77  0.474
2013 Wu L, Zhao JC, Kim J, Jin HJ, Wang CY, Yu J. ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer. Cancer Research. 73: 6068-79. PMID 23913826 DOI: 10.1158/0008-5472.Can-13-0882  0.35
2013 Chang J, Liu F, Lee M, Wu B, Ting K, Zara JN, Soo C, Al Hezaimi K, Zou W, Chen X, Mooney DJ, Wang CY. NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation. Proceedings of the National Academy of Sciences of the United States of America. 110: 9469-74. PMID 23690607 DOI: 10.1073/Pnas.1300532110  0.386
2013 Ding X, Pan H, Li J, Zhong Q, Chen X, Dry SM, Wang CY. Epigenetic activation of AP1 promotes squamous cell carcinoma metastasis. Science Signaling. 6: ra28.1-13, S0-15. PMID 23633675 DOI: 10.1126/Scisignal.2003884  0.343
2013 Herath TD, Darveau RP, Seneviratne CJ, Wang CY, Wang Y, Jin L. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-κB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts. Plos One. 8: e58496. PMID 23554896 DOI: 10.1371/Journal.Pone.0058496  0.31
2013 Puckett MC, Goldman EH, Cockrell LM, Huang B, Kasinski AL, Du Y, Wang CY, Lin A, Ichijo H, Khuri F, Fu H. Integration of apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/protein kinase B-IκB kinase cascade. Molecular and Cellular Biology. 33: 2252-9. PMID 23530055 DOI: 10.1128/Mcb.00047-13  0.348
2013 Bianco P, Cao X, Frenette PS, Mao JJ, Robey PG, Simmons PJ, Wang CY. The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nature Medicine. 19: 35-42. PMID 23296015 DOI: 10.1038/Nm.3028  0.328
2012 Luo W, Wang CY, Jin L. Baicalin downregulates Porphyromonas gingivalis lipopolysaccharide-upregulated IL-6 and IL-8 expression in human oral keratinocytes by negative regulation of TLR signaling. Plos One. 7: e51008. PMID 23239998 DOI: 10.1371/Journal.Pone.0051008  0.302
2012 Ramadoss S, Chen X, Wang CY. Histone demethylase KDM6B promotes epithelial-mesenchymal transition. The Journal of Biological Chemistry. 287: 44508-17. PMID 23152497 DOI: 10.1074/Jbc.M112.424903  0.347
2012 Ye L, Fan Z, Yu B, Chang J, Al Hezaimi K, Zhou X, Park NH, Wang CY. Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs. Cell Stem Cell. 11: 50-61. PMID 22770241 DOI: 10.1016/J.Stem.2012.04.009  0.463
2012 Zhao B, Li L, Wang L, Wang CY, Yu J, Guan KL. Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes & Development. 26: 54-68. PMID 22215811 DOI: 10.1101/Gad.173435.111  0.401
2011 Xie X, Zhang D, Zhao B, Lu MK, You M, Condorelli G, Wang CY, Guan KL. IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 108: 6474-9. PMID 21464307 DOI: 10.1073/Pnas.1016132108  0.305
2011 Dong L, Wang YX, Li SL, Yu GY, Gan YH, Li D, Wang CY. TGF-beta1 promotes migration and invasion of salivary adenoid cystic carcinoma. Journal of Dental Research. 90: 804-9. PMID 21441221 DOI: 10.1177/0022034511401407  0.314
2011 Ramadoss S, Li J, Ding X, Al Hezaimi K, Wang CY. Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation. Molecular and Cellular Biology. 31: 924-34. PMID 21189284 DOI: 10.1128/Mcb.00576-10  0.36
2011 Ramadoss S, Li J, Ding X, Wang C. Abstract 3103: Transducin β-like protein 1 promotes cancer cell invasion by recruiting nuclear factor-κB to target gene promoter for transcriptional activation Cancer Research. 71: 3103-3103. DOI: 10.1158/1538-7445.Am2011-3103  0.367
2010 Krum SA, Chang J, Miranda-Carboni G, Wang CY. Novel functions for NFκB: inhibition of bone formation. Nature Reviews. Rheumatology. 6: 607-11. PMID 20703218 DOI: 10.1038/Nrrheum.2010.133  0.336
2010 Song J, Chang I, Chen Z, Kang M, Wang CY. Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling. Plos One. 5: e11456. PMID 20625515 DOI: 10.1371/Journal.Pone.0011456  0.344
2010 Kim J, Guan J, Chang I, Chen X, Han D, Wang CY. PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells. Molecular Cancer Therapeutics. 9: 1977-84. PMID 20571067 DOI: 10.1158/1535-7163.Mct-10-0141  0.339
2010 Tang ED, Wang CY. TRAF5 is a downstream target of MAVS in antiviral innate immune signaling. Plos One. 5: e9172. PMID 20161788 DOI: 10.1371/Journal.Pone.0009172  0.312
2010 Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y. Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proceedings of the National Academy of Sciences of the United States of America. 107: 1431-6. PMID 20080598 DOI: 10.1073/Pnas.0911409107  0.345
2010 Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes & Development. 24: 72-85. PMID 20048001 DOI: 10.1101/Gad.1843810  0.307
2010 Goto M, Mitra RS, Liu M, Lee J, Henson BS, Carey T, Bradford C, Prince M, Wang CY, Fearon ER, D'Silva NJ. Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 65-76. PMID 20028760 DOI: 10.1158/1078-0432.Ccr-09-1122  0.313
2009 Rehman AO, Wang CY. CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex. International Journal of Oral Science. 1: 105-18. PMID 20695076 DOI: 10.4248/Ijos.09059  0.309
2009 Fan Z, Yamaza T, Lee JS, Yu J, Wang S, Fan G, Shi S, Wang CY. BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nature Cell Biology. 11: 1002-9. PMID 19578371 DOI: 10.1038/Ncb1913  0.344
2009 Chang J, Wang Z, Tang E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY. Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nature Medicine. 15: 682-9. PMID 19448637 DOI: 10.1038/Nm.1954  0.332
2009 Tang ED, Wang CY. MAVS self-association mediates antiviral innate immune signaling. Journal of Virology. 83: 3420-8. PMID 19193783 DOI: 10.1128/Jvi.02623-08  0.319
2009 Hu K, Li SL, Gan YH, Wang CY, Yu GY. Epiregulin promotes migration and invasion of salivary adenoid cystic carcinoma cell line SACC-83 through activation of ERK and Akt. Oral Oncology. 45: 156-63. PMID 18620900 DOI: 10.1016/J.Oraloncology.2008.04.009  0.34
2008 Yamaza T, Miura Y, Bi Y, Liu Y, Akiyama K, Sonoyama W, Patel V, Gutkind S, Young M, Gronthos S, Le A, Wang CY, Chen W, Shi S. Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. Plos One. 3: e2615. PMID 18612428 DOI: 10.1371/Journal.Pone.0002615  0.307
2008 Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL. TEAD mediates YAP-dependent gene induction and growth control. Genes & Development. 22: 1962-71. PMID 18579750 DOI: 10.1101/Gad.1664408  0.381
2008 Kasinski AL, Du Y, Thomas SL, Zhao J, Sun SY, Khuri FR, Wang CY, Shoji M, Sun A, Snyder JP, Liotta D, Fu H. Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Molecular Pharmacology. 74: 654-61. PMID 18577686 DOI: 10.1124/Mol.108.046201  0.364
2008 Rehman AO, Wang CY. SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB. The Journal of Biological Chemistry. 283: 19888-94. PMID 18448428 DOI: 10.1074/Jbc.M710432200  0.313
2008 Li J, Wang CY. TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis. Nature Cell Biology. 10: 160-9. PMID 18193033 DOI: 10.1038/Ncb1684  0.303
2008 Liu F, Kohlmeier S, Wang CY. Wnt signaling and skeletal development. Cellular Signalling. 20: 999-1009. PMID 18164181 DOI: 10.1016/J.Cellsig.2007.11.011  0.335
2007 Li Y, Wang Y, Kim E, Beemiller P, Wang CY, Swanson J, You M, Guan KL. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb. The Journal of Biological Chemistry. 282: 35803-13. PMID 17928295 DOI: 10.1074/Jbc.M705231200  0.367
2007 Chang J, Sonoyama W, Wang Z, Jin Q, Zhang C, Krebsbach PH, Giannobile W, Shi S, Wang CY. Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. The Journal of Biological Chemistry. 282: 30938-48. PMID 17720811 DOI: 10.1074/Jbc.M702391200  0.391
2007 Cude K, Wang Y, Choi HJ, Hsuan SL, Zhang H, Wang CY, Xia Z. Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway. The Journal of Cell Biology. 177: 253-64. PMID 17452529 DOI: 10.1083/Jcb.200609166  0.327
2007 Wang J, Wang J, Dai J, Jung Y, Wei CL, Wang Y, Havens AM, Hogg PJ, Keller ET, Pienta KJ, Nor JE, Wang CY, Taichman RS. A glycolytic mechanism regulating an angiogenic switch in prostate cancer. Cancer Research. 67: 149-59. PMID 17210694 DOI: 10.1158/0008-5472.Can-06-2971  0.316
2007 Park BK, Zhang H, Zeng Q, Dai J, Keller ET, Giordano T, Gu K, Shah V, Pei L, Zarbo RJ, McCauley L, Shi S, Chen S, Wang CY. NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nature Medicine. 13: 62-9. PMID 17159986 DOI: 10.1038/Nm1519  0.337
2006 Sonoyama W, Liu Y, Fang D, Yamaza T, Seo BM, Zhang C, Liu H, Gronthos S, Wang CY, Wang S, Shi S. Mesenchymal stem cell-mediated functional tooth regeneration in swine. Plos One. 1: e79. PMID 17183711 DOI: 10.1371/Journal.Pone.0000079  0.311
2006 Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell. 126: 955-68. PMID 16959574 DOI: 10.1016/J.Cell.2006.06.055  0.389
2006 Fribley AM, Evenchik B, Zeng Q, Park BK, Guan JY, Zhang H, Hale TJ, Soengas MS, Kaufman RJ, Wang CY. Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa. The Journal of Biological Chemistry. 281: 31440-7. PMID 16928686 DOI: 10.1074/Jbc.M604356200  0.343
2006 Carayol N, Chen J, Yang F, Jin T, Jin L, States D, Wang CY. A dominant function of IKK/NF-κB signaling in global lipopolysaccharide-induced gene expression Journal of Biological Chemistry. 281: 31142-31151. PMID 16914552 DOI: 10.1074/Jbc.M603417200  0.336
2006 Fribley A, Wang CY. Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. Cancer Biology & Therapy. 5: 745-8. PMID 16861900 DOI: 10.4161/Cbt.5.7.2971  0.37
2006 Rehman AO, Wang CY. Notch signaling in the regulation of tumor angiogenesis. Trends in Cell Biology. 16: 293-300. PMID 16697642 DOI: 10.1016/J.Tcb.2006.04.003  0.331
2006 Gronthos S, Akintoye SO, Wang CY, Shi S. Bone marrow stromal stem cells for tissue engineering. Periodontology 2000. 41: 188-95. PMID 16686934 DOI: 10.1111/J.1600-0757.2006.00154.X  0.304
2006 Yang F, Zeng Q, Yu G, Li S, Wang CY. Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC. Cellular Signalling. 18: 679-87. PMID 16084063 DOI: 10.1016/J.Cellsig.2005.06.015  0.361
2005 Zhang H, Kim JK, Edwards CA, Xu Z, Taichman R, Wang CY. Clusterin inhibits apoptosis by interacting with activated Bax. Nature Cell Biology. 7: 909-15. PMID 16113678 DOI: 10.1038/Ncb1291  0.329
2005 Zeng Q, Li S, Chepeha DB, Giordano TJ, Li J, Zhang H, Polverini PJ, Nor J, Kitajewski J, Wang CY. Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell. 8: 13-23. PMID 16023595 DOI: 10.1016/J.Ccr.2005.06.004  0.348
2005 Wang J, Wang J, Sun Y, Song W, Nor JE, Wang CY, Taichman RS. Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis. Cellular Signalling. 17: 1578-92. PMID 16005185 DOI: 10.1016/J.Cellsig.2005.03.022  0.37
2005 Karl E, Warner K, Zeitlin B, Kaneko T, Wurtzel L, Jin T, Chang J, Wang S, Wang CY, Strieter RM, Nunez G, Polverini PJ, Nör JE. Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines. Cancer Research. 65: 5063-9. PMID 15958549 DOI: 10.1158/0008-5472.Can-05-0140  0.36
2004 Fribley A, Zeng Q, Wang CY. Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Molecular and Cellular Biology. 24: 9695-704. PMID 15509775 DOI: 10.1128/Mcb.24.22.9695-9704.2004  0.359
2004 Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, Young M, Robey PG, Wang CY, Shi S. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet (London, England). 364: 149-55. PMID 15246727 DOI: 10.1016/S0140-6736(04)16627-0  0.31
2004 Yang F, Yamashita J, Tang E, Wang HL, Guan K, Wang CY. The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop. Journal of Immunology (Baltimore, Md. : 1950). 172: 2446-52. PMID 14764716 DOI: 10.4049/Jimmunol.172.4.2446  0.33
2003 Tang ED, Inohara N, Wang CY, Nuñez G, Guan KL. Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected]. The Journal of Biological Chemistry. 278: 38566-70. PMID 12890679 DOI: 10.1074/Jbc.M304374200  0.328
2003 Tang ED, Wang CY, Xiong Y, Guan KL. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 278: 37297-305. PMID 12867425 DOI: 10.1074/Jbc.M303389200  0.306
2003 Yang F, Tang E, Guan K, Wang CY. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 170: 5630-5. PMID 12759443 DOI: 10.4049/Jimmunol.170.11.5630  0.317
2003 Gronthos S, Chen S, Wang CY, Robey PG, Shi S. Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 716-22. PMID 12674332 DOI: 10.1359/Jbmr.2003.18.4.716  0.358
2002 Reuther-Madrid JY, Kashatus D, Chen S, Li X, Westwick J, Davis RJ, Earp HS, Wang CY, Baldwin Jr AS. The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor. Molecular and Cellular Biology. 22: 8175-83. PMID 12417721 DOI: 10.1128/Mcb.22.23.8175-8183.2002  0.377
2002 Zeng Q, McCauley LK, Wang CY. Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression. The Journal of Biological Chemistry. 277: 50137-42. PMID 12393863 DOI: 10.1074/Jbc.M208952200  0.408
2002 Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nature Biotechnology. 20: 587-91. PMID 12042862 DOI: 10.1038/Nbt0602-587  0.35
2002 Zeng Q, Chen S, You Z, Yang F, Carey TE, Saims D, Wang CY. Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B. The Journal of Biological Chemistry. 277: 25203-8. PMID 11994287 DOI: 10.1074/Jbc.M201598200  0.389
2002 You Z, Saims D, Chen S, Zhang Z, Guttridge DC, Guan KL, MacDougald OA, Brown AM, Evan G, Kitajewski J, Wang CY. Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. The Journal of Cell Biology. 157: 429-40. PMID 11980918 DOI: 10.1083/Jcb.200201110  0.326
2002 Chen HL, Demiralp B, Schneider A, Koh AJ, Silve C, Wang CY, McCauley LK. Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells. The Journal of Biological Chemistry. 277: 19374-81. PMID 11897779 DOI: 10.1074/Jbc.M108913200  0.365
2001 You Z, Ouyang H, Lopatin D, Polverini PJ, Wang C. Nuclear factor-kappaB-inducible death effector domain-containing protein suppressesTNF-mediated apoptosis by inhibiting caspase-8 activity Journal of Biological Chemistry. PMID 11346652 DOI: 10.1074/Jbc.M102464200  0.34
2001 Chen S, Guttridge DC, You Z, Zhang Z, Fribley A, Mayo MW, Kitajewski J, Wang CY. Wnt-1 signaling inhibits apoptosis by activating β-catenin/T cell factor-mediated transcription Journal of Cell Biology. 152: 87-96. PMID 11149923 DOI: 10.1083/Jcb.152.1.87  0.394
2000 Madrid LV, Wang CY, Guttridge DC, Schottelius AJ, Baldwin AS, Mayo MW. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Molecular and Cellular Biology. 20: 1626-38. PMID 10669740 DOI: 10.1128/Mcb.20.5.1626-1638.2000  0.344
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