Year |
Citation |
Score |
2018 |
Chen M, Yan R, Zhou K, Li X, Zhang Y, Liu C, Jiang M, Ye H, Meng X, Pang N, Zhao L, Liu J, Xiao W, Hu R, Cui Q, ... ... Lin A, et al. Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia. Proceedings of the National Academy of Sciences of the United States of America. PMID 30337485 DOI: 10.1182/Blood-2018-99-114952 |
0.315 |
|
2018 |
Yan J, Zhang H, Xiang J, Zhao Y, Yuan X, Sun B, Lin A. The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock. Cell Research. PMID 29795446 DOI: 10.1038/S41422-018-0041-7 |
0.47 |
|
2015 |
Zhao Y, Lin Y, Zhang H, Mañas A, Tang W, Zhang Y, Wu D, Lin A, Xiang J. Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195787 DOI: 10.1073/Pnas.1508647112 |
0.332 |
|
2015 |
Li J, Lin A, Yu C, Zhang Z, Xu D, Hu W, Liu L, Wang S, Nie X, Sun W, Gai Z, Chen Z. Association of Enterovirus 71 encephalitis with the interleukin-8 gene region in Chinese children. Infectious Diseases (London, England). 47: 418-22. PMID 25751776 DOI: 10.3109/00365548.2015.1007473 |
0.619 |
|
2013 |
Puckett MC, Goldman EH, Cockrell LM, Huang B, Kasinski AL, Du Y, Wang CY, Lin A, Ichijo H, Khuri F, Fu H. Integration of apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/protein kinase B-IκB kinase cascade. Molecular and Cellular Biology. 33: 2252-9. PMID 23530055 DOI: 10.1128/Mcb.00047-13 |
0.445 |
|
2013 |
Do-Umehara HC, Chen C, Urich D, Zhou L, Qiu J, Jang S, Zander A, Baker MA, Eilers M, Sporn PH, Ridge KM, Sznajder JI, Budinger GR, Mutlu GM, Lin A, et al. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nature Immunology. 14: 461-9. PMID 23525087 DOI: 10.1038/Ni.2566 |
0.324 |
|
2013 |
Yan J, Xiang J, Lin Y, Ma J, Zhang J, Zhang H, Sun J, Danial NN, Liu J, Lin A. Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation. Cell. 152: 304-15. PMID 23332762 DOI: 10.1016/J.Cell.2012.12.021 |
0.564 |
|
2012 |
Lin YL, Yu CI, Hu YC, Tsai TJ, Kuo YC, Chi WK, Lin AN, Chiang BL. Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles. Vaccine. 30: 1305-12. PMID 22214888 DOI: 10.1016/j.vaccine.2011.12.081 |
0.598 |
|
2012 |
Liu J, Yan J, Jiang S, Wen J, Chen L, Zhao Y, Lin A. Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α-induced JNK activation and inflammation. Proceedings of the National Academy of Sciences of the United States of America. 109: 191-6. PMID 22184250 DOI: 10.1073/Pnas.1105176108 |
0.42 |
|
2011 |
Lin A. ATIA: a link between inflammation and hypoxia. Molecular Cell. 42: 557-8. PMID 21658597 DOI: 10.1016/J.Molcel.2011.05.023 |
0.375 |
|
2011 |
Dong B, Wang FH, Lin AJ, Yu CH, Guo LP, Xie WJ, Feng L, Hu Y. [Isolation and degradation characteristics of acetochlor-degrading strain A-3]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 32: 542-7. PMID 21528581 |
0.599 |
|
2011 |
Deng H, Zhang J, Yoon T, Song D, Li D, Lin A. Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells. The International Journal of Biochemistry & Cell Biology. 43: 409-15. PMID 21095239 DOI: 10.1016/J.Biocel.2010.11.011 |
0.484 |
|
2011 |
Lin A. Temporal control of TNFα signaling by miz1 Advances in Experimental Medicine and Biology. 691: 127-128. DOI: 10.1007/978-1-4419-6612-4_13 |
0.371 |
|
2009 |
Liu J, Zhao Y, Eilers M, Lin A. Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 18279-84. PMID 19815509 DOI: 10.1073/Pnas.0906328106 |
0.466 |
|
2009 |
Tang F, Kokontis J, Lin Y, Liao S, Lin A, Xiang J. Androgen via p21 inhibits tumor necrosis factor alpha-induced JNK activation and apoptosis. The Journal of Biological Chemistry. 284: 32353-8. PMID 19723627 DOI: 10.1074/Jbc.M109.042994 |
0.413 |
|
2009 |
Chen JL, Lin HH, Kim KJ, Lin A, Ou JH, Ann DK. PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis. Autophagy. 5: 244-6. PMID 19098423 DOI: 10.4161/auto.5.2.7549 |
0.303 |
|
2008 |
Zhang J, Wang Q, Zhu N, Yu M, Shen B, Xiang J, Lin A. Cyclic AMP inhibits JNK activation by CREB-mediated induction of c-FLIP(L) and MKP-1, thereby antagonizing UV-induced apoptosis. Cell Death and Differentiation. 15: 1654-62. PMID 18566605 DOI: 10.1038/Cdd.2008.87 |
0.509 |
|
2008 |
Deng H, Yu F, Chen J, Zhao Y, Xiang J, Lin A. Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. The Journal of Biological Chemistry. 283: 20754-60. PMID 18469002 DOI: 10.1074/Jbc.M800024200 |
0.489 |
|
2007 |
Zhang J, Shen B, Lin A. Novel strategies for inhibition of the p38 MAPK pathway. Trends in Pharmacological Sciences. 28: 286-95. PMID 17482683 DOI: 10.1016/J.Tips.2007.04.008 |
0.352 |
|
2007 |
Wang J, Minemoto Y, Lin A, Li Y, Shen B, Zhang J. IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-kappaB activity. Molecular Immunology. 44: 2139-43. PMID 17118453 DOI: 10.1016/J.Molimm.2006.10.007 |
0.42 |
|
2006 |
Graham WV, Wang F, Clayburgh DR, Cheng JX, Yoon B, Wang Y, Lin A, Turner JR. Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. The Journal of Biological Chemistry. 281: 26205-15. PMID 16835238 DOI: 10.1074/Jbc.M602164200 |
0.384 |
|
2006 |
Schachter KA, Du Y, Lin A, Gallo KA. Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains. The Journal of Biological Chemistry. 281: 19134-44. PMID 16687404 DOI: 10.1074/Jbc.M603324200 |
0.418 |
|
2006 |
Hickson JA, Huo D, Vander Griend DJ, Lin A, Rinker-Schaeffer CW, Yamada SD. The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma Cancer Research. 66: 2264-2270. PMID 16489030 DOI: 10.1158/0008-5472.Can-05-3676 |
0.405 |
|
2006 |
Liu J, Yang D, Minemoto Y, Leitges M, Rosner MR, Lin A. NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Molecular Cell. 21: 467-80. PMID 16483929 DOI: 10.1016/J.Molcel.2005.12.020 |
0.533 |
|
2006 |
Lin Y, Kokontis J, Tang F, Godfrey B, Liao S, Lin A, Chen Y, Xiang J. Androgen and its receptor promote Bax-mediated apoptosis. Molecular and Cellular Biology. 26: 1908-16. PMID 16479009 DOI: 10.1128/Mcb.26.5.1908-1916.2006 |
0.324 |
|
2006 |
Zhang J, Bui TN, Xiang J, Lin A. Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain Molecular and Cellular Biology. 26: 1223-1234. PMID 16449637 DOI: 10.1128/Mcb.26.4.1223-1234.2006 |
0.476 |
|
2006 |
Zu K, Bihani T, Lin A, Park YM, Mori K, Ip C. Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells. Oncogene. 25: 546-54. PMID 16205645 DOI: 10.1038/sj.onc.1209071 |
0.325 |
|
2005 |
Vander Griend DJ, Kocherginsky M, Hickson JA, Stadler WM, Lin A, Rinker-Schaeffer CW. Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7 Cancer Research. 65: 10984-10991. PMID 16322247 DOI: 10.1158/0008-5472.Can-05-2382 |
0.423 |
|
2005 |
Zhang J, Liu J, Yu C, Lin A. BAD Ser128 is not phosphorylated by c-Jun NH2-terminal kinase for promoting apoptosis. Cancer Research. 65: 8372-8. PMID 16166315 DOI: 10.1158/0008-5472.Can-05-0576 |
0.713 |
|
2005 |
Liu J, Lin A. Role of JNK activation in apoptosis: a double-edged sword. Cell Research. 15: 36-42. PMID 15686625 DOI: 10.1038/Sj.Cr.7290262 |
0.487 |
|
2004 |
Liu J, Minemoto Y, Lin A. c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis. Molecular and Cellular Biology. 24: 10844-56. PMID 15572687 DOI: 10.1128/Mcb.24.24.10844-10856.2004 |
0.494 |
|
2004 |
Yu C, Minemoto Y, Zhang J, Liu J, Tang F, Bui TN, Xiang J, Lin A. JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD Molecular Cell. 13: 329-340. PMID 14967141 DOI: 10.1016/S1097-2765(04)00028-0 |
0.719 |
|
2004 |
Liu H, Ma Y, Pagliari LJ, Perlman H, Yu C, Lin A, Pope RM. TNF-alpha-induced apoptosis of macrophages following inhibition of NF-kappa B: a central role for disruption of mitochondria. Journal of Immunology (Baltimore, Md. : 1950). 172: 1907-15. PMID 14734776 DOI: 10.4049/Jimmunol.172.3.1907 |
0.714 |
|
2003 |
Page K, Li J, Zhou L, Iasvovskaia S, Corbit KC, Soh JW, Weinstein IB, Brasier AR, Lin A, Hershenson MB, Iasvoyskaia S. Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C delta. Journal of Immunology (Baltimore, Md. : 1950). 170: 5681-9. PMID 12759450 DOI: 10.4049/Jimmunol.170.11.5681 |
0.384 |
|
2003 |
Lin A, Karin M. NF-kappaB in cancer: a marked target. Seminars in Cancer Biology. 13: 107-14. PMID 12654254 DOI: 10.1016/S1044-579X(02)00128-1 |
0.422 |
|
2003 |
Zhou L, Tan A, Iasvovskaia S, Li J, Lin A, Hershenson MB. Ras and mitogen-activated protein kinase kinase kinase-1 coregulate activator protein-1- and nuclear factor-kappaB-mediated gene expression in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 28: 762-9. PMID 12600818 DOI: 10.1165/Rcmb.2002-0261Oc |
0.448 |
|
2003 |
Lin A. Activation of the JNK signaling pathway: Breaking the brake on apoptosis Bioessays. 25: 17-24. PMID 12508278 DOI: 10.1002/Bies.10204 |
0.434 |
|
2003 |
Li J, Johnson XD, Iazvovskaia S, Tan A, Lin A, Hershenson MB. Signaling intermediates required for NF-kappa B activation and IL-8 expression in CF bronchial epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L307-15. PMID 12388360 DOI: 10.1152/ajplung.00086.2002 |
0.376 |
|
2002 |
Lin A, Dibling B. The true face of JNK activation in apoptosis. Aging Cell. 1: 112-6. PMID 12882340 DOI: 10.1046/J.1474-9728.2002.00014.X |
0.439 |
|
2002 |
Gupta S, Purcell NH, Lin A, Sen S. Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. The Journal of Cell Biology. 159: 1019-28. PMID 12486112 DOI: 10.1083/Jcb.200207149 |
0.768 |
|
2002 |
Tang F, Tang G, Xiang J, Dai Q, Rosner MR, Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Molecular and Cellular Biology. 22: 8571-9. PMID 12446776 DOI: 10.1128/Mcb.22.24.8571-8579.2002 |
0.482 |
|
2002 |
Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nature Immunology. 3: 221-7. PMID 11875461 DOI: 10.1038/Ni0302-221 |
0.406 |
|
2002 |
Tang G, Yang J, Minemoto Y, Lin A. Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis. Molecular Cell. 8: 1005-16. PMID 11741536 DOI: 10.1016/S1097-2765(01)00380-X |
0.475 |
|
2001 |
Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, Lin A. Inhibition of JNK activation through NF-kappaB target genes. Nature. 414: 313-7. PMID 11713531 DOI: 10.1038/35104568 |
0.757 |
|
2001 |
Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA, Lin A. Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 6668-73. PMID 11381115 DOI: 10.1073/Pnas.111155798 |
0.75 |
|
2001 |
Purcell NH, Yu C, He D, Xiang J, Paran N, DiDonato JA, Yamaoka S, Shaul Y, Lin A. Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase-independent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G669-77. PMID 11254493 DOI: 10.1152/Ajpgi.2001.280.4.G669 |
0.752 |
|
1999 |
Engelman JA, Berg AH, Lewis RY, Lin A, Lisanti MP, Scherer PE. Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. The Journal of Biological Chemistry. 274: 35630-8. PMID 10585441 DOI: 10.1074/Jbc.274.50.35630 |
0.403 |
|
1999 |
He H, Li HL, Lin A, Gottlieb RA. Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia. Cell Death and Differentiation. 6: 987-91. PMID 10556976 DOI: 10.1038/sj.cdd.4400572 |
0.311 |
|
1998 |
Nemoto S, DiDonato JA, Lin A. Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase. Molecular and Cellular Biology. 18: 7336-43. PMID 9819420 DOI: 10.1128/Mcb.18.12.7336 |
0.501 |
|
1998 |
Nemoto S, Xiang J, Huang S, Lin A. Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. The Journal of Biological Chemistry. 273: 16415-20. PMID 9632706 DOI: 10.1074/Jbc.273.26.16415 |
0.46 |
|
1998 |
Nemoto S, Sheng Z, Lin A. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Molecular and Cellular Biology. 18: 3518-26. PMID 9584192 DOI: 10.1128/Mcb.18.6.3518 |
0.445 |
|
1997 |
Lu X, Nemoto S, Lin A. Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38. The Journal of Biological Chemistry. 272: 24751-4. PMID 9312068 DOI: 10.1074/Jbc.272.40.24751 |
0.432 |
|
1997 |
Jiang Y, Li Z, Schwarz EM, Lin A, Guan K, Ulevitch RJ, Han J. Structure-function studies of p38 mitogen-activated protein kinase. Loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection. The Journal of Biological Chemistry. 272: 11096-102. PMID 9111004 DOI: 10.1074/Jbc.272.17.11096 |
0.359 |
|
1996 |
Cavigelli M, Li WW, Lin A, Su B, Yoshioka K, Karin M. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. The Embo Journal. 15: 6269-6279. DOI: 10.1002/j.1460-2075.1996.tb01017.x |
0.344 |
|
1995 |
Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M. Identification of a dual specificity kinase that activates the jun kinases and p38-Mpk2 Science. 268: 286-290. PMID 7716521 DOI: 10.1126/Science.7716521 |
0.432 |
|
1995 |
Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs Cell. 81: 1147-1157. PMID 7600582 DOI: 10.1016/S0092-8674(05)80019-4 |
0.467 |
|
1994 |
Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK Science. 266: 1719-1723. PMID 7992057 DOI: 10.1126/Science.7992057 |
0.453 |
|
1994 |
Minden A, Lin A, Smeal T, Dérijard B, Cobb M, Davis R, Karin M. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases Molecular and Cellular Biology. 14: 6683-6688. PMID 7935387 DOI: 10.1128/mcb.14.10.6683-6688.1994 |
0.427 |
|
1993 |
Alberts AS, Deng T, Lin A, Meinkoth JL, Schönthal A, Mumby MC, Karin M, Feramisco JR. Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Molecular and Cellular Biology. 13: 2104-12. PMID 8384305 DOI: 10.1128/Mcb.13.4.2104 |
0.412 |
|
1993 |
Yu CC, Lee YH, Huang JK, Chen MT, Chen KK, Lin AT, Chang LS. Long-term stone regrowth and recurrence rates after extracorporeal shock wave lithotripsy. British Journal of Urology. 72: 688-91. PMID 8281395 |
0.594 |
|
1993 |
Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain Genes and Development. 7: 2135-2148. PMID 8224842 DOI: 10.1101/Gad.7.11.2135 |
0.409 |
|
1992 |
Lin A, Frost J, Deng T, Smeal T, al-Alawi N, Kikkawa U, Hunter T, Brenner D, Karin M. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell. 70: 777-89. PMID 1516134 DOI: 10.1016/0092-8674(92)90311-Y |
0.412 |
|
1991 |
Yu CC, Chen KK, Chen MT, Huang JK, Lin AT, Lee YH, Chang LS. Serum iron as a tumor marker in renal cell carcinoma. European Urology. 19: 54-8. PMID 2007419 |
0.599 |
|
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