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Eric C. Polley, Ph.D. - Publications

Affiliations: 
2010 Biostatistics University of California, Berkeley, Berkeley, CA, United States 
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Year Citation  Score
2022 Iversen ES, Lipton G, Hart SN, Lee KY, Hu C, Polley EC, Pesaran T, Yussuf A, LaDuca H, Chao E, Karam R, Goldgar DE, Couch FJ, Monteiro ANA. An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance. Npj Genomic Medicine. 7: 35. PMID 35665744 DOI: 10.1038/s41525-022-00302-3  0.322
2020 Hart SN, Polley EC, Yussuf A, Yadav S, Goldgar DE, Hu C, LaDuca H, Smith LP, Fujimoto J, Li S, Couch FJ, Dolinsky JS. Mutation prevalence tables for hereditary cancer derived from multi-gene panel testing. Human Mutation. PMID 32442341 DOI: 10.1002/Humu.24053  0.371
2020 Palmer JR, Polley EC, Hu C, John EM, Haiman C, Hart SN, Gaudet M, Pal T, Anton-Culver H, Trentham-Dietz A, Bernstein L, Ambrosone CB, Bandera EV, Bertrand KA, Bethea TN, et al. Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women. Journal of the National Cancer Institute. PMID 32427313 DOI: 10.1093/Jnci/Djaa040  0.393
2020 Yadav S, Hu C, Hart SN, Boddicker N, Polley EC, Na J, Gnanaolivu R, Lee KY, Lindstrom T, Armasu S, Fitz-Gibbon P, Ghosh K, Stan DL, Pruthi S, Neal L, et al. Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1902190. PMID 32125938 DOI: 10.1200/Jco.19.02190  0.35
2020 Golmakani MK, Polley EC. Super Learner for Survival Data Prediction. The International Journal of Biostatistics. PMID 32097120 DOI: 10.1515/Ijb-2019-0065  0.326
2020 Hu C, Polley EC, Yadav S, Lilyquist J, Shimelis H, Na J, Hart SN, Goldgar DE, Shah S, Pesaran T, Dolinsky JS, LaDuca H, Couch FJ. The contribution of germline predisposition gene mutations to clinical subtypes of invasive breast cancer from a clinical genetic testing cohort. Journal of the National Cancer Institute. PMID 32091585 DOI: 10.1093/Jnci/Djaa023  0.399
2020 Gao C, Polley EC, Hu C, Hart SN, Gnanaolivu R, Lee KY, Na J, Boddicker NJ, Samara R, Auer P, Bernstein L, Gaudet M, Trentham-Dietz A, Yao S, Haiman C, et al. Abstract PD3-02: Polygenic risk scores provide clinically meaningful risk stratification among women carrying moderate penetrance pathogenic variants in breast cancer predisposition genes: Results from the CARRIERS study Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd3-02  0.401
2020 Couch FJ, Hu C, Hart SN, Gnanaolivu R, Lee KY, Na J, Gao C, Boddicker NJ, Eckloff B, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, Bernstein L, ... ... Polley EC, et al. Abstract PD3-01: Population-based breast cancer risk estimates for predisposition gene mutations: Results from the CARRIERS study Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd3-01  0.419
2020 Yadav S, LaDuca H, Polley EC, Hu C, Hart SN, Na J, Gnanaolivu R, Smith B, Goldgar DE, Pesaran T, Dolinsky JS, Couch FJ. Abstract P6-08-04: Germline mutations in cancer predisposition genes in patients with invasive lobular carcinoma of the breast Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P6-08-04  0.366
2020 Yadav S, Hu C, Hart SN, Boddicker N, Polley EC, Na J, Gnanaolivu R, Lee KY, Olson JE, Ruddy KJ, Couch FJ. Abstract P6-08-01: Comparison of recommendations for germline genetic testing in an unselected cohort of patients with breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P6-08-01  0.367
2020 Black MH, Li S, LaDuca H, Armasu S, Polley EC, Fitz-Gibbon P, Scott CG, Winham SJ, Olson JE, Ruddy KJ, Vachon CM, Couch FJ. Abstract P5-07-06: Performance of a polygenic risk score combined with clinical assessment for breast cancer risk Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-07-06  0.4
2020 Giridhar KV, Choong GM, Yadav S, Polley EC, Leon-Ferre RA, Liu MC, Goetz MP, Couch FJ. Abstract P5-03-07: Distribution of the 21-gene recurrence score (RS) assay (Oncotype DX) in carriers of germline mutations associated with breast cancer predisposition syndromes Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-03-07  0.367
2019 Li H, LaDuca H, Pesaran T, Chao EC, Dolinsky JS, Parsons M, Spurdle AB, Polley EC, Shimelis H, Hart SN, Hu C, Couch FJ, Goldgar DE. Classification of variants of uncertain significance in BRCA1 and BRCA2 using personal and family history of cancer from individuals in a large hereditary cancer multigene panel testing cohort. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31853058 DOI: 10.1038/S41436-019-0729-1  0.371
2019 Choudhery S, Polley E, Conners AL. Assessment of MRI-detected lesions on screening tomosynthesis in patients with newly diagnosed breast cancer. Clinical Imaging. 59: 50-55. PMID 31760277 DOI: 10.1016/J.Clinimag.2019.09.007  0.312
2019 LaDuca H, Polley EC, Yussuf A, Hoang L, Gutierrez S, Hart SN, Yadav S, Hu C, Na J, Goldgar DE, Fulk K, Smith LP, Horton C, Profato J, Pesaran T, et al. A clinical guide to hereditary cancer panel testing: evaluation of gene-specific cancer associations and sensitivity of genetic testing criteria in a cohort of 165,000 high-risk patients. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31406321 DOI: 10.1038/S41436-019-0633-8  0.398
2019 Vachon CM, Scott CG, Tamimi RM, Thompson DJ, Fasching PA, Stone J, Southey MC, Winham S, Lindström S, Lilyquist J, Giles GG, Milne RL, MacInnis RJ, Baglietto L, Li J, ... ... Polley EC, et al. Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk. Breast Cancer Research : Bcr. 21: 68. PMID 31118087 DOI: 10.1186/S13058-019-1138-8  0.328
2019 Liu Y, Chanana P, Davila JI, Hou X, Zanfagnin V, McGehee CD, Goode EL, Polley EC, Haluska P, Weroha SJ, Wang C. Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts. Scientific Reports. 9: 6314. PMID 31004097 DOI: 10.1038/S41598-019-42680-2  0.307
2019 Yang SX, Polley EC. Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up. Breast Cancer Research and Treatment. PMID 30746635 DOI: 10.1007/S10549-019-05142-X  0.349
2019 Long B, Lilyquist J, Weaver A, Hu C, Gnanaolivu R, Lee KY, Hart SN, Polley EC, Bakkum-Gamez JN, Couch FJ, Dowdy SC. Cancer susceptibility gene mutations in type I and II endometrial cancer. Gynecologic Oncology. 152: 20-25. PMID 30612635 DOI: 10.1016/J.Ygyno.2018.10.019  0.39
2019 Yadav S, LaDuca H, Polley E, Shimelis H, Niguidula N, Hu C, Lilyquist J, Na J, Lee K, Gutierrez S, Yussuf A, Hart S, Davis BT, Chao E, Pesaran T, et al. Racial and ethnic differences in the results of multigene panel testing of inherited cancer predisposition genes in breast cancer patients. Journal of Clinical Oncology. 37: 1514-1514. DOI: 10.1200/Jco.2019.37.15_Suppl.1514  0.402
2019 Palmer JR, Hu C, Hart S, Gnanaolivu RD, Gao C, Anton-Culver H, Trentham-Dietz A, Bernstein L, Weitzel JN, Domchek SM, Goldgar D, Nathanson K, Pal T, John EM, Gaudet M, ... ... Polley E, et al. Genetic predisposition to breast cancer among African American women. Journal of Clinical Oncology. 37: 104-104. DOI: 10.1200/Jco.2019.37.15_Suppl.104  0.412
2019 Couch F, Hu C, Hart S, Gnanaolivu R, Lilyquist J, Lee K, Gao C, Eckloff B, Samara R, Klebba J, Auer P, Bernstein L, Gaudet M, Haiman C, Palmer J, ... ... Polley E, et al. Abstract GS2-01: Age-related breast cancer risk estimates for the general population based on sequencing of cancer predisposition genes in 19,228 breast cancer patients and 20,211 matched unaffected controls from US based cohorts in the CARRIERS study Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs2-01  0.422
2019 Gao C, Hu C, Hart SN, Gnanaolivu R, Lee KY, Lilyquist J, Boddicker NJ, Eckloff B, Samara R, Klebba J, Auer P, Bernstein L, Gaudet M, Anton-Culver H, Trentham-Dietz A, ... ... Polley EC, et al. Abstract 4177: The joint effects of polygenic risk scores and pathogenic variants in cancer predisposition genes on breast cancer risk in the general population: results from the CARRIERS study Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-4177  0.383
2019 Couch FJ, Hu C, Hart SN, Gnanaolivu R, Lilyquist J, Lee KY, Gao C, Eckloff B, Anton-Culver H, Auer P, Bernstein L, Gaudet M, Haiman C, Palmer J, Tentham-Dietz A, ... ... Polley EC, et al. Abstract 4169: Population-based breast cancer risk estimates associated with cancer predisposition gene mutations from 32,298 breast cancer patients and 31,869 matched unaffected controls from the CARRIERS study Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-4169  0.409
2019 Hughitt VK, Gorjifard S, Michalowski AM, Simmons JK, Dale R, Polley EC, Keats JJ, Mock BA. Abstract 5113: A flexible pipeline for precision medicine biomarker detection and prediction of treatment response Cancer Research. 79: 5113-5113. DOI: 10.1158/1538-7445.Am2019-5113  0.414
2018 Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, Tyrer JP, Chen TH, Wang Q, Bolla MK, Yang X, Adank MA, Ahearn T, Aittomäki K, Allen J, ... ... Polley EC, et al. Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. American Journal of Human Genetics. PMID 30554720 DOI: 10.1016/J.Ajhg.2018.11.002  0.388
2018 Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, et al. The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel. Cancer Research. PMID 30355619 DOI: 10.1158/0008-5472.Can-18-0989  0.335
2018 Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, et al. Interaction between the microbiome and TP53 in human lung cancer. Genome Biology. 19: 123. PMID 30143034 DOI: 10.1186/S13059-018-1501-6  0.334
2018 Shimelis H, LaDuca H, Hu C, Hart SN, Na J, Thomas A, Akinhanmi M, Moore RM, Brauch H, Cox A, Eccles DM, Ewart-Toland A, Fasching PA, Fostira F, Garber J, ... ... Polley EC, et al. Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing. Journal of the National Cancer Institute. PMID 30099541 DOI: 10.1093/Jnci/Djy106  0.398
2018 Antwi SO, Fagan SE, Chaffee KG, Bamlet WR, Hu C, Polley EC, Hart SN, Shimelis H, Lilyquist J, Gnanaolivu RD, McWilliams RR, Oberg AL, Couch FJ, Petersen GM. Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status. Journal of the National Cancer Institute. PMID 29982661 DOI: 10.1093/Jnci/Djx272  0.378
2018 Hu C, Hart SN, Polley EC, Gnanaolivu R, Shimelis H, Lee KY, Lilyquist J, Na J, Moore R, Antwi SO, Bamlet WR, Chaffee KG, DiCarlo J, Wu Z, Samara R, et al. Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer. Jama. 319: 2401-2409. PMID 29922827 DOI: 10.1001/Jama.2018.6228  0.382
2018 Hart SN, Hoskin T, Shimelis H, Moore RM, Feng B, Thomas A, Lindor NM, Polley EC, Goldgar DE, Iversen E, Monteiro ANA, Suman VJ, Couch FJ. Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 29884841 DOI: 10.1038/S41436-018-0018-4  0.321
2018 Kasi PM, Couch F, Bamlet WR, Hu C, Hart S, Polley E, Petersen GM, McWilliams RR. Germline BRCA1/2, PALB2, and ATM mutations in 3,030 patients with pancreatic adenocarcinoma: Survival analysis of carriers and noncarriers. Journal of Clinical Oncology. 36: 280-280. DOI: 10.1200/Jco.2018.36.4_Suppl.280  0.352
2018 Couch F, Shimelis H, Dolinsky JS, Polley E, Horton C, Yussuf A, Hoang L, Lilyquist J, Speare V, Hu C, Hart S, LaDuca H. Expanding BRCA1/2 testing criteria to include other confirmed breast and ovarian cancer susceptibility genes. Journal of Clinical Oncology. 36: 1524-1524. DOI: 10.1200/Jco.2018.36.15_Suppl.1524  0.414
2018 Fasching P, Hu C, Hart S, Polley E, Lee K, Gnanolivu R, Lilyquist J, Hartkopf A, Taran F, Janni W, Hadji P, Tesch H, Haeberle L, Ettl J, Lux M, et al. Abstract PD1-02: Cancer predisposition genes in metastatic breast cancer – Association with metastatic pattern, prognosis, patient and tumor characteristics Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Pd1-02  0.414
2018 Couch F, Shimelis H, LaDuca H, Hu C, Hart S, Polley E, Pesaran T, Tippin-Davis B, Goldgar D, Dolinsky J. Abstract PD1-01: Triple negative breast cancer predisposition genes Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Pd1-01  0.438
2018 Lilyquist J, Laduca H, Hu C, Na J, Polley E, Hart S, Pesaran T, Tippin-Davis B, Goldgar D, Dolinsky J, Couch F. Abstract P6-09-02: Associations between hereditary cancer panel predisposition genes and breast cancer histological subtypes Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P6-09-02  0.42
2018 Liu M, Cummings S, Vachon C, Kerlikowske K, Couch F, Morris E, Olson J, Polley E, Conners A, Ellis R, Patel B, Maimone S, Zhang N, Hamilton S, Clarke C, et al. Abstract OT3-02-01: Development of cell-free nucleic acid-based tests for early detection of breast cancer: The STRIVE study Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Ot3-02-01  0.403
2017 Lilyquist J, LaDuca H, Polley E, Davis BT, Shimelis H, Hu C, Hart SN, Dolinsky JS, Couch FJ, Goldgar DE. Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls. Gynecologic Oncology. PMID 28888541 DOI: 10.1016/J.Ygyno.2017.08.030  0.402
2017 Holbeck SL, Camalier R, Crowell JA, Govindharajulu JP, Hollingshead MG, Anderson LW, Polley EC, Rubinstein L, Srivastava AK, Wilsker DF, Collins JM, Doroshow JH. The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity. Cancer Research. PMID 28446463 DOI: 10.1158/0008-5472.Can-17-0489  0.385
2017 Couch FJ, Shimelis H, Hu C, Hart SN, Polley EC, Na J, Hallberg E, Moore R, Thomas A, Lilyquist J, Feng B, McFarland R, Pesaran T, Huether R, LaDuca H, et al. Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer. Jama Oncology. PMID 28418444 DOI: 10.1001/Jamaoncol.2017.0424  0.413
2017 Yang SX, Polley EC, Nguyen D. Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer. Theranostics. 7: 945-951. PMID 28382166 DOI: 10.7150/Thno.19102  0.341
2017 Lih CJ, Harrington RD, Sims DJ, Harper KN, Bouk CH, Datta V, Yau J, Singh RR, Routbort MJ, Luthra R, Patel KP, Mantha GS, Krishnamurthy S, Ronski K, Walther Z, ... ... Polley EC, et al. Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial. The Journal of Molecular Diagnostics : Jmd. PMID 28188106 DOI: 10.1016/J.Jmoldx.2016.10.007  0.361
2017 Yang SX, Polley E. Survival profile in breast cancer molecular subtypes without systemic and locoregional treatment. Journal of Clinical Oncology. 35: 11599-11599. DOI: 10.1200/Jco.2017.35.15_Suppl.11599  0.345
2017 Couch F, Hu C, Lilyquist J, Shimelis H, Akinhanmi M, Na J, Polley E, Hart S, McFarland R, LaDuca H, Huether R, Goldgar D, Dolinsky J. Abstract S2-01: Breast cancer risks associated with mutations in cancer predisposition genes identified by clinical genetic testing of 60,000 breast cancer patients Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-S2-01  0.434
2017 Couch F, Lilyquist J, Na J, Hu C, Polley E, Shimelis H, Akinhanmi M, McFarland R, LaDuca H, Goldgar D, Dolinsky J. Abstract P5-09-03: Associations between breast cancer subtypes and mutations in cancer predisposition genes identified by clinical genetic testing of breast cancer patients Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-09-03  0.428
2017 Greathouse L, White J, Bliskovsky V, Vargas A, Polley E, Bowman E, Khan M, Robles A, Ryan B, Dzutsev A, Trinchieri G, Pineda M, Bilke S, Meltzer P, Walther-Antonio M, et al. Abstract 4925: Microbiome-TP53 gene interaction in human lung cancer Cancer Research. 77: 4925-4925. DOI: 10.1158/1538-7445.Am2017-4925  0.353
2017 LaDuca H, Hu C, Shimelis H, Polley E, Lilyquist J, Black MH, Davis BT, Goldgar DE, Dolinsky J, Couch FJ. Abstract 4286: What have we learned from pancreatic cancer patients undergoing multigene panel testing Epidemiology. 77: 4286-4286. DOI: 10.1158/1538-7445.Am2017-4286  0.34
2017 Lilyquist J, LaDuca H, Polley E, Shimelis H, Hu C, Moore R, Hart SN, Couch FJ, Dolinsky J, Goldgar DE. Abstract 1287: Multigene panel testing and risk estimates in 10,233 ovarian cancer cases Epidemiology. 77: 1287-1287. DOI: 10.1158/1538-7445.Am2017-1287  0.33
2016 Palmisano A, Zhao Y, Li MC, Polley EC, Simon RM. OpenGeneMed: a portable, flexible and customizable informatics hub for the coordination of next-generation sequencing studies in support of precision medicine trials. Briefings in Bioinformatics. PMID 27422621 DOI: 10.1093/bib/bbw059  0.343
2016 Polley E, Kunkel M, Evans D, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Connelly J, Harris E, Fer N, Sonkin D, Kaur G, Monks A, et al. Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression. Journal of the National Cancer Institute. 108. PMID 27247353 DOI: 10.1093/Jnci/Djw122  0.326
2016 Chang LC, Das B, Lih CJ, Si H, Camalier CE, McGregor PM, Polley E. RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing. Cancer Informatics. 15: 65-71. PMID 27147817 DOI: 10.4137/Cin.S36612  0.327
2016 Yang SX, Polley E, Lipkowitz S. New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer. Cancer Treatment Reviews. 45: 87-96. PMID 26995633 DOI: 10.1016/J.Ctrv.2016.03.004  0.412
2016 Goldstein BA, Polley EC, Briggs FB, van der Laan MJ, Hubbard A. Testing the Relative Performance of Data Adaptive Prediction Algorithms: A Generalized Test of Conditional Risk Differences. The International Journal of Biostatistics. 12: 117-29. PMID 26529567 DOI: 10.1515/Ijb-2015-0014  0.615
2016 Chen AP, Williams M, Kummar S, Lih C, Datta V, Polley E, Zhao Y, Rubinstein L, O'Sullivan Coyne GH, Meehan RS, Moore N, Sharon E, Palmisano A, Sims D, Harrington R, et al. Feasibility of molecular profiling based assignment of cancer treatment (MPACT): A randomized NCI precision medicine study. Journal of Clinical Oncology. 34: 2539-2539. DOI: 10.1200/Jco.2016.34.15_Suppl.2539  0.366
2015 Kaur G, Reinhart RA, Monks A, Evans D, Morris J, Polley E, Teicher BA. Bromodomain and hedgehog pathway targets in small cell lung cancer. Cancer Letters. PMID 26683772 DOI: 10.1016/J.Canlet.2015.12.001  0.372
2015 Lih CJ, Sims DJ, Harrington RD, Polley EC, Zhao Y, Mehaffey MG, Forbes TD, Das B, Walsh WD, Datta V, Harper KN, Bouk CH, Rubinstein LV, Simon RM, Conley BA, et al. Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial. The Journal of Molecular Diagnostics : Jmd. PMID 26602013 DOI: 10.1016/J.Jmoldx.2015.07.006  0.387
2015 Teicher BA, Polley E, Kunkel M, Evans D, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Connelly J, Harris E, Monks A, Morris J. Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression. Molecular Cancer Therapeutics. 14: 2452-62. PMID 26351324 DOI: 10.1158/1535-7163.Mct-15-0074  0.34
2015 Zhao Y, Polley EC, Li MC, Lih CJ, Palmisano A, Sims DJ, Rubinstein LV, Conley BA, Chen AP, Williams PM, Kummar S, Doroshow JH, Simon RM. GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials. Cancer Informatics. 14: 45-55. PMID 25861217 DOI: 10.4137/Cin.S17282  0.381
2015 Kummar S, Williams PM, Lih CJ, Polley EC, Chen AP, Rubinstein LV, Zhao Y, Simon RM, Conley BA, Doroshow JH. Application of molecular profiling in clinical trials for advanced metastatic cancers. Journal of the National Cancer Institute. 107. PMID 25663694 DOI: 10.1093/Jnci/Djv003  0.383
2015 Kaur G, Polley E, Morris J, Silvers T, Selby M, Delosh R, Laudeman J, Ogle C, Reinhart R, Monks A, Rapisarda A, Evans D, Teicher BA. Abstract 5406: Osteosarcoma cell lines response to approved and investigational anticancer agents and statins along with gene and microRNA expression Cancer Research. 75: 5406-5406. DOI: 10.1158/1538-7445.Am2015-5406  0.324
2014 Kummar S, Williams M, Lih C, Chen AP, Rubinstein L, Antony R, Polley E, Zhao Y, Conley BA, Simon R, Doroshow JH. NCI mpact: National Cancer Institute molecular profiling-based assignment of cancer therapy. Journal of Clinical Oncology. 32: TPS2642-TPS2642. DOI: 10.1200/Jco.2014.32.15_Suppl.Tps2642  0.37
2014 Polley E, Monks A, Morris J, Rapisarda A, Kaur G, Mertins S, Connelly J, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Evans D, Teicher BA. Sarcoma gene expression and response to approved and investigational agents: Focus on osteosarcoma. Journal of Clinical Oncology. 32: e22067-e22067. DOI: 10.1200/Jco.2014.32.15_Suppl.E22067  0.323
2014 Morris J, Kunkel M, Polley E, Holbeck S, Monks A, Evans D, Rapisarda A, Collins J, Teicher B. Abstract 5475: Interrogation of NCI-60 patterns of growth inhibition in conjunction with investigational oncology agents kinase profiling for the elucidation of mechanistic targets Cancer Research. 74: 5475-5475. DOI: 10.1158/1538-7445.Am2014-5475  0.334
2014 Evans DM, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Silvers T, Connelly J, Monks A, Polley E, Kaur G, Morris J, Teicher B. Abstract 5450: Screening more than 60 human SCLC lines with approved and investigational agents indicates complex patterns of response: Identification of HSP90 and HDACs as potential targets Cancer Research. 74: 5450-5450. DOI: 10.1158/1538-7445.Am2014-5450  0.336
2014 Wrzeszczynski KO, Polley EC, Hose C, Monks A, Teicher BA. Abstract 2361: Identification and analysis of gene fusion and splice variant events in the NCI sarcoma cell line panel Cancer Research. 74: 2361-2361. DOI: 10.1158/1538-7445.Am2014-2361  0.374
2014 Lih C, Sims D, Harrington R, Polley E, Zhao Y, Simon R, Mehaffey M, Forbes T, Walsh W, Datta V, Conley B, Chen A, Kummar S, Doroshow J, Williams P. 233 Analytical validation and application of the MPACT assay, a next generation sequencing based targeted mutation detection assay for treatment selection European Journal of Cancer. 50: 78. DOI: 10.1016/S0959-8049(14)70359-4  0.301
2014 Hose C, Zhao Y, Polley E, Fang J, Fer N, Rapisarda A, Teicher B, Simon R, Doroshow J, Monks A. 171 Antagonistic interaction between gemcitabine and erlotinib is influenced by EGR1 (early growth response 1) transcription factor expression European Journal of Cancer. 50: 57. DOI: 10.1016/S0959-8049(14)70297-7  0.332
2013 Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology. Cancer Research. 73: 4372-82. PMID 23856246 DOI: 10.1158/0008-5472.Can-12-3342  0.394
2013 Kilpatrick RD, Gilbertson D, Brookhart MA, Polley E, Rothman KJ, Bradbury BD. Exploring large weight deletion and the ability to balance confounders when using inverse probability of treatment weighting in the presence of rare treatment decisions. Pharmacoepidemiology and Drug Safety. 22: 111-21. PMID 22674782 DOI: 10.1002/Pds.3297  0.465
2013 Simon R, Polley E. Clinical trials for precision oncology using next-generation sequencing Personalized Medicine. 10: 485-495. DOI: 10.2217/Pme.13.36  0.354
2013 Monks A, Rapisarda A, Wrzeszczynski KO, August EM, Polley EC, Kondapaka SB, Kaur G, Newton D, Teicher BA. Abstract 4361: Target and drug discovery for recalcitrant, rare and neglected cancers. Cancer Research. 73: 4361-4361. DOI: 10.1158/1538-7445.Am2013-4361  0.41
2013 Hays JL, Polley EC, David JJ, Lu J, Leone AM, Mehta S, Kohn EC. Abstract C124: Proteomic and phenotype derived model for selection of combinations of targeted therapies in ovarian cancer. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C124  0.373
2013 Monks A, Evans D, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Connelly J, Rapisarda A, Kunkel M, Morris J, Wrzeszczynski K, Polley E, Teicher B. Abstract C103: Sarcoma cell line sensitivity towards approved oncology drugs and investigational agents identifies distinct patterns of response which can be interrogated with associated gene expression. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C103  0.363
2013 Morris J, Kunkel M, Polley E, Holbeck S, Wrzeszczynski K, Monks A, Evans D, Rapisarda A, Collins J, Teicher BA. Abstract A102: NCI-60 response profiles of >400 investigational oncology agents: A resource enabling drug and biomarker discovery. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A102  0.357
2013 Lih C, Sims D, Polley E, Zhao Y, Mehaffey M, Forbes T, Harrington R, Walsh W, McGregor P, Simon R, Conley B, Kummar S, Doroshow J, Williams P. MC13-0060 Analytical validation of the MPACT assay, a targeted next generation sequencing clinical assay for cancer patient treatment selection European Journal of Cancer. 49: S11. DOI: 10.1016/S0959-8049(13)70117-5  0.351
2012 Abaan OD, Davis SR, Bilke S, Polley EC, Walker RL, Pineda M, Zhu YJ, Reinhold W, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. Abstract 1879: The exomes of the NCI60 and their implications for cancer pharmacogenomics Cancer Research. 72: 1879-1879. DOI: 10.1158/1538-7445.Am2012-1879  0.411
2011 Namiki T, Tanemura A, Valencia JC, Coelho SG, Passeron T, Kawaguchi M, Vieira WD, Ishikawa M, Nishijima W, Izumo T, Kaneko Y, Katayama I, Yamaguchi Y, Yin L, Polley EC, et al. AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 6597-602. PMID 21460252 DOI: 10.1073/Pnas.1007694108  0.337
2010 Kilpatrick R, Bradbury B, Gilbertson D, Brookhart M, Polley E, Rothman K. Using IPTW Marginal Structural Modeling to Balance Confounding by Indication Annals of Epidemiology. 20: 717. DOI: 10.1016/J.Annepidem.2010.07.075  0.45
2007 van der Laan MJ, Polley EC, Hubbard AE. Super learner. Statistical Applications in Genetics and Molecular Biology. 6: Article25. PMID 17910531 DOI: 10.2202/1544-6115.1309  0.58
2007 Sinisi SE, Polley EC, Petersen ML, Rhee SY, van der Laan MJ. Super learning: an application to the prediction of HIV-1 drug resistance. Statistical Applications in Genetics and Molecular Biology. 6: Article7. PMID 17402922 DOI: 10.2202/1544-6115.1240  0.662
Low-probability matches (unlikely to be authored by this person)
2016 Yang SX, Polley E, Nguyen D. Association of gamma-H2AX expression with clinopathologic characteristics and clinical outcomes in breast cancer. Journal of Clinical Oncology. 34: 11577-11577. DOI: 10.1200/Jco.2016.34.15_Suppl.11577  0.299
2014 Polley MY, Polley EC, Huang EP, Freidlin B, Simon R. Two-stage adaptive cutoff design for building and validating a prognostic biomarker signature. Statistics in Medicine. 33: 5097-110. PMID 25263614 DOI: 10.1002/Sim.6310  0.295
2016 Sims DJ, Harrington RD, Polley EC, Forbes TD, Mehaffey MG, McGregor PM, Camalier CE, Harper KN, Bouk CH, Das B, Conley BA, Doroshow JH, Williams PM, Lih CJ. Plasmid-Based Materials as Multiplex Quality Controls and Calibrators for Clinical Next-Generation Sequencing Assays. The Journal of Molecular Diagnostics : Jmd. 18: 336-49. PMID 27105923 DOI: 10.1016/J.Jmoldx.2015.11.008  0.295
2017 Kummar S, O'Sullivan Coyne G, Do KT, Turkbey B, Meltzer PS, Polley E, Choyke PL, Meehan R, Vilimas R, Horneffer Y, Juwara L, Lih A, Choudhary A, Mitchell SA, Helman LJ, et al. Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016711994. PMID 28350521 DOI: 10.1200/Jco.2016.71.1994  0.293
2015 Elkins JM, Fedele V, Szklarz M, Abdul Azeez KR, Salah E, Mikolajczyk J, Romanov S, Sepetov N, Huang XP, Roth BL, Al Haj Zen A, Fourches D, Muratov E, Tropsha A, Morris J, ... ... Polley E, et al. Comprehensive characterization of the Published Kinase Inhibitor Set. Nature Biotechnology. PMID 26501955 DOI: 10.1038/Nbt.3374  0.286
2018 Kohli M, Hart S, Lilyquist J, Hu C, Hillman DW, Lee K, Gnanaolivu RD, Polley E, Couch F. Prognostic impact of DNA repair germline variants in hormone sensitive prostate cancer stage. Journal of Clinical Oncology. 36: 262-262. DOI: 10.1200/Jco.2018.36.6_Suppl.262  0.286
2011 Goldstein BA, Polley EC, Briggs FB. Random forests for genetic association studies. Statistical Applications in Genetics and Molecular Biology. 10: 32. PMID 22889876 DOI: 10.2202/1544-6115.1691  0.283
2018 Hu C, LaDuca H, Shimelis H, Polley EC, Lilyquist J, Hart SN, Na J, Thomas A, Lee KY, Davis BT, Black MH, Pesaran T, Goldgar DE, Dolinsky JS, Couch FJ. Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes. Jco Precision Oncology. 2. PMID 31497750 DOI: 10.1200/PO.17.00291  0.283
2021 Fasching PA, Yadav S, Hu C, Wunderle M, Häberle L, Hart SN, Rübner M, Polley EC, Lee KY, Gnanaolivu RD, Hadji P, Hübner H, Tesch H, Ettl J, Overkamp F, et al. Mutations in and Other Panel Genes in Patients With Metastatic Breast Cancer -Association With Patient and Disease Characteristics and Effect on Prognosis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2001200. PMID 33780288 DOI: 10.1200/JCO.20.01200  0.281
2023 Hu C, Belur Nagaraj A, Shimelis H, Montalban G, Lee KY, Huang H, Lumby CA, Na J, Susswein LR, Roberts ME, Marshall ML, Hiraki S, LaDuca H, Chao E, Yussuf A, ... ... Polley EC, et al. Functional and clinical characterization of variants of uncertain significance identifies a hotspot for inactivating missense variants in RAD51C. Cancer Research. PMID 37253112 DOI: 10.1158/0008-5472.CAN-22-2319  0.281
2020 Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, et al. Author Correction: Interaction between the microbiome and TP53 in human lung cancer. Genome Biology. 21: 41. PMID 32079537 DOI: 10.1186/S13059-020-01961-0  0.281
2014 Bando H, Lih J, Polley E, Holbeck S, Das B, Sims D, Doi T, Ohtsu A, Williams M, Takebe N. 101 PIK3CA mutation-targeting compounds analyses using NCI60 cell line panel European Journal of Cancer. 50: 36-37. DOI: 10.1016/S0959-8049(14)70227-8  0.279
2021 Hu C, Hart SN, Gnanaolivu R, Huang H, Lee KY, Na J, Gao C, Lilyquist J, Yadav S, Boddicker NJ, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, ... ... Polley EC, et al. A Population-Based Study of Genes Previously Implicated in Breast Cancer. The New England Journal of Medicine. PMID 33471974 DOI: 10.1056/NEJMoa2005936  0.276
2021 Gao C, Polley EC, Hart SN, Huang H, Hu C, Gnanaolivu R, Lilyquist J, Boddicker NJ, Na J, Ambrosone CB, Auer PL, Bernstein L, Burnside ES, Eliassen AH, Gaudet MM, et al. Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2001992. PMID 34101481 DOI: 10.1200/JCO.20.01992  0.267
2017 Liu H, Antony S, Roy K, Juhasz A, Wu Y, Lu J, Meitzler JL, Jiang G, Polley E, Doroshow JH. Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. Oncotarget. PMID 28498822 DOI: 10.18632/Oncotarget.17494  0.266
2014 Evans D, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Silvers T, Monks A, Polley E, Kaur G, Morris J, Teicher B. 78 A comprehensive in vitro screen to identify therapeutic candidates for inclusion with etoposide/platin combinations to improve treatment of SCLC European Journal of Cancer. 50: 30. DOI: 10.1016/S0959-8049(14)70204-7  0.262
2022 Hu C, Susswein LR, Roberts ME, Yang H, Marshall ML, Hiraki S, Berkofsky-Fessler W, Gupta S, Shen W, Dunn CA, Huang H, Na J, Domchek SM, Yadav S, Monteiro ANA, ... Polley EC, et al. Classification of BRCA2 variants of uncertain significance (VUS) using an ACMG/AMP model incorporating a homology directed repair (HDR) functional assay. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 35736817 DOI: 10.1158/1078-0432.CCR-22-0203  0.256
2021 Coignard J, Lush M, Beesley J, O'Mara TA, Dennis J, Tyrer JP, Barnes DR, McGuffog L, Leslie G, Bolla MK, Adank MA, Agata S, Ahearn T, Aittomäki K, Andrulis IL, ... ... Polley EC, et al. Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Nature Communications. 12: 2986. PMID 33990587 DOI: 10.1038/s41467-021-23162-4  0.253
2023 Morra A, Schreurs MAC, Andrulis IL, Anton-Culver H, Augustinsson A, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brauch H, Broeks A, Buys SS, Camp NJ, Castelao JE, Cessna MH, ... ... Polley EC, et al. Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival. Cancer Medicine. PMID 37401034 DOI: 10.1002/cam4.6272  0.253
2021 Coignard J, Lush M, Beesley J, O'Mara TA, Dennis J, Tyrer JP, Barnes DR, McGuffog L, Leslie G, Bolla MK, Adank MA, Agata S, Ahearn T, Aittomäki K, Andrulis IL, ... ... Polley EC, et al. A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Nature Communications. 12: 1078. PMID 33597508 DOI: 10.1038/s41467-020-20496-3  0.253
2019 Paim AC, Cummins NW, Natesampillai S, Garcia-Rivera E, Kogan N, Neogi U, Sönnerborg A, Sperk M, Bren GD, Deeks S, Polley E, Badley AD. HIV elite control is associated with reduced TRAILshort expression. Aids (London, England). PMID 31149947 DOI: 10.1097/Qad.0000000000002279  0.245
2013 Byakika-Tusiime J, Polley EC, Oyugi JH, Bangsberg DR. Free HIV antiretroviral therapy enhances adherence among individuals on stable treatment: implications for potential shortfalls in free antiretroviral therapy. Plos One. 8: e70375. PMID 24039704 DOI: 10.1371/Journal.Pone.0070375  0.244
2018 Natesampillai S, Cummins NW, Nie Z, Sampath R, Baker JV, Henry K, Pinzone M, O'Doherty U, Polley EC, Bren GD, Katzmann DJ, Badley AD. The proapoptotic, HIV protease generated Casp8p41 when bound and inactivated by Bcl2, is degraded by the proteasome. Journal of Virology. PMID 29643240 DOI: 10.1128/Jvi.00037-18  0.238
2023 Yadav S, Boddicker NJ, Na J, Polley EC, Hu C, Hart SN, Gnanaolivu RD, Larson N, Holtegaard S, Huang H, Dunn CA, Teras LR, Patel AV, Lacey JV, Neuhausen SL, et al. Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in , , , , and . Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2201239. PMID 36623243 DOI: 10.1200/JCO.22.01239  0.237
2015 Kummar S, Do KT, O'Sullivan Coyne GH, Turkbey B, Meltzer PS, Polley E, Horneffer Y, Juwara L, Antony R, Choyke PL, Mitchell SA, Helman LJ, Chen A, Doroshow JH. Phase II trial of PF-03084014 in adults with desmoid tumors/aggressive fibromatosis. Journal of Clinical Oncology. 33: 10563-10563. DOI: 10.1200/Jco.2015.33.15_Suppl.10563  0.236
2021 Boddicker NJ, Hu C, Weitzel JN, Kraft P, Nathanson KL, Goldgar DE, Na J, Huang H, Gnanaolivu RD, Larson N, Yussuf A, Yao S, Vachon CM, Trentham-Dietz A, Teras L, ... ... Polley EC, et al. Risk of Late-Onset Breast Cancer in Genetically Predisposed Women. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2100531. PMID 34292776 DOI: 10.1200/JCO.21.00531  0.236
2021 Yadav S, Hu C, Nathanson KL, Weitzel JN, Goldgar DE, Kraft P, Gnanaolivu RD, Na J, Huang H, Boddicker NJ, Larson N, Gao C, Yao S, Weinberg C, Vachon CM, ... ... Polley EC, et al. Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2100640. PMID 34672684 DOI: 10.1200/JCO.21.00640  0.236
2015 Do K, Speranza G, Chang LC, Polley EC, Bishop R, Zhu W, Trepel JB, Lee S, Lee MJ, Kinders RJ, Phillips L, Collins J, Lyons J, Jeong W, Antony R, et al. Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors. Investigational New Drugs. 33: 921-30. PMID 26082332 DOI: 10.1007/S10637-015-0255-1  0.233
2013 Simon R, Polley E. Clinical trials for precision oncology using next-generation sequencing. Personalized Medicine. 10: 485-495. PMID 29758837 DOI: 10.2217/pme.13.36  0.233
2012 Kong HH, Oh J, Deming C, Conlan S, Grice EA, Beatson MA, Nomicos E, Polley EC, Komarow HD, Murray PR, Turner ML, Segre JA. Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis. Genome Research. 22: 850-9. PMID 22310478 DOI: 10.1101/Gr.131029.111  0.232
2020 Kapoor PM, Mavaddat N, Choudhury PP, Wilcox AN, Lindström S, Behrens S, Michailidou K, Dennis J, Bolla MK, Wang Q, Jung A, Abu-Ful Z, Ahearn T, Andrulis IL, Anton-Culver H, ... ... Polley EC, et al. Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. Journal of the National Cancer Institute. PMID 32359158 DOI: 10.1093/Jnci/Djaa056  0.232
2016 O'Sullivan Coyne GH, Kummar S, Do KT, Choyke PL, Turkbey B, Polley E, Horneffer Y, Juwara L, Vilimas RJ, Meehan RS, Helman LJ, Doroshow JH, Chen AP. Activity of PF-03084014 in adults with desmoid tumors/aggressive fibromatosis. Journal of Clinical Oncology. 34: 11028-11028. DOI: 10.1200/Jco.2016.34.15_Suppl.11028  0.231
2021 Chen AP, Kummar S, Moore N, Rubinstein LV, Zhao Y, Williams PM, Palmisano A, Sims D, O'Sullivan Coyne G, Rosenberger CL, Simpson M, Raghav KPS, Meric-Bernstam F, Leong S, Waqar S, ... ... Polley E, et al. Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial. Jco Precision Oncology. 5. PMID 33928209 DOI: 10.1200/PO.20.00372  0.23
2013 Kummar S, Allen D, Monks A, Polley EC, Hose CD, Ivy SP, Turkbey IB, Lawrence S, Kinders RJ, Choyke P, Simon R, Steinberg SM, Doroshow JH, Helman L. Cediranib for metastatic alveolar soft part sarcoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2296-302. PMID 23630200 DOI: 10.1200/Jco.2012.47.4288  0.23
2021 Gu J, Polley EC, Denis M, Carter JM, Pruthi S, Gregory AV, Boughey JC, Fazzio RT, Fatemi M, Alizad A. Early assessment of shear wave elastography parameters foresees the response to neoadjuvant chemotherapy in patients with invasive breast cancer. Breast Cancer Research : Bcr. 23: 52. PMID 33926522 DOI: 10.1186/s13058-021-01429-4  0.228
2023 Morris J, Kunkel MW, White SL, Wishka DG, Lopez OD, Bowles L, Sellers Brady P, Ramsey P, Grams J, Rohrer T, Martin K, Dexheimer TS, Coussens NP, Evans D, Risbood P, ... ... Polley EC, et al. Targeted Investigational Oncology Agents (IOA) in the NCI60: A Phenotypic Systems-Based Resource. Molecular Cancer Therapeutics. PMID 37550087 DOI: 10.1158/1535-7163.MCT-23-0267  0.227
2024 Hu C, Huang H, Na J, Lumby C, Abozaid M, Holdren MA, Rao TJ, Karam R, Pesaran T, Weyandt JD, Csuy CM, Seelaus CA, Young CC, Fulk K, Heidari Z, ... ... Polley EC, et al. Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain. American Journal of Human Genetics. PMID 38417439 DOI: 10.1016/j.ajhg.2024.02.002  0.225
2018 Daniels LM, Sorita A, Kashiwagi DT, Okubo M, Small E, Polley EC, Sawatsky AP. Characterizing Potentially Preventable Admissions: A Mixed Methods Study of Rates, Associated Factors, Outcomes, and Physician Decision-Making. Journal of General Internal Medicine. PMID 29340940 DOI: 10.1007/S11606-017-4285-6  0.223
2021 Richardson ME, Hu C, Lee KY, LaDuca H, Fulk K, Durda KM, Deckman AM, Goldgar DE, Monteiro ANA, Gnanaolivu R, Hart SN, Polley EC, Chao E, Pesaran T, Couch FJ. Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance. American Journal of Human Genetics. PMID 33609447 DOI: 10.1016/j.ajhg.2021.02.005  0.221
2013 Polley M, Polley E, Huang E, Freidlin B, Simon R. MC13-0049 Two-stage adaptive cutoff design for building and validating a prognostic biomarker signature European Journal of Cancer. 49. DOI: 10.1016/S0959-8049(13)70116-3  0.22
2020 Gregory A, Denis M, Bayat M, Kumar V, Kim BH, Webb J, Nayak R, Adabi S, Meixner DD, Polley EC, Fazzio RT, Fatemi M, Alizad A. Predictive value of comb-push ultrasound shear elastography for the differentiation of reactive and metastatic axillary lymph nodes: A preliminary investigation. Plos One. 15: e0226994. PMID 31929558 DOI: 10.1371/Journal.Pone.0226994  0.219
2020 Yadav S, LaDuca H, Polley EC, Hu C, Niguidula N, Shimelis H, Lilyquist J, Na J, Lee KY, Gutierrez S, Yussuf A, Hart SN, Davis BT, Chao EC, Pesaran T, et al. Racial and ethnic differences in multigene hereditary cancer panel test results for women with breast cancer. Journal of the National Cancer Institute. PMID 33146377 DOI: 10.1093/jnci/djaa167  0.215
2021 Domchek SM, Yao S, Chen F, Hu C, Hart SN, Goldgar DE, Nathanson KL, Ambrosone CB, Haiman CA, Couch FJ, Polley EC, Palmer JR. Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States. Jama Oncology. PMID 34042955 DOI: 10.1001/jamaoncol.2021.1492  0.208
2018 Glatz M, Jo JH, Kennedy EA, Polley EC, Segre JA, Simpson EL, Kong HH. Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis. Plos One. 13: e0192443. PMID 29489859 DOI: 10.1371/Journal.Pone.0192443  0.206
2021 Ternifi R, Wang Y, Wang Y, Polley EC, Fazzio RT, Fatemi M, Alizad A. Quantitative Biomarkers for Cancer Detection Using Contrast-Free Ultrasound High-Definition Microvessel Imaging: Fractal Dimension, Murray's Deviation, Bifurcation Angle & Spatial Vascularity Pattern. Ieee Transactions On Medical Imaging. PMID 34329160 DOI: 10.1109/TMI.2021.3101669  0.206
2016 Jo JH, Deming C, Kennedy EA, Conlan S, Polley EC, Ng WL, Segre JA, Kong HH. Diverse human skin fungal communities in children converge in adulthood. The Journal of Investigative Dermatology. PMID 27476723 DOI: 10.1016/J.Jid.2016.05.130  0.206
2023 Morra A, Schreurs MAC, Andrulis IL, Anton-Culver H, Augustinsson A, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brauch H, Broeks A, Buys SS, Camp NJ, Castelao JE, Cessna MH, ... ... Polley EC, et al. Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival. Research Square. PMID 36824750 DOI: 10.21203/rs.3.rs-2569372/v1  0.203
2012 Oh J, Conlan S, Polley EC, Segre JA, Kong HH. Shifts in human skin and nares microbiota of healthy children and adults. Genome Medicine. 4: 77. PMID 23050952 DOI: 10.1186/Gm378  0.197
2019 Yadav S, Hart SN, Hu C, Hillman D, Lee KY, Gnanaolivu R, Na J, Polley EC, Couch FJ, Kohli M. Contribution of Inherited DNA-Repair Gene Mutations to Hormone-Sensitive and Castrate-Resistant Metastatic Prostate Cancer and Implications for Clinical Outcome. Jco Precision Oncology. 3. PMID 32923857 DOI: 10.1200/PO.19.00067  0.19
2020 Hart SN, Polley EC, Shimelis H, Yadav S, Couch FJ. Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML. Npj Breast Cancer. 6: 13. PMID 33579916 DOI: 10.1038/s41523-020-0159-x  0.181
2020 Hart SN, Polley EC, Shimelis H, Yadav S, Couch FJ. Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML. Npj Breast Cancer. 6: 13. PMID 32377563 DOI: 10.1038/s41523-020-0159-x  0.181
2020 Matejcic M, Patel Y, Lilyquist J, Hu C, Lee KY, Gnanaolivu RD, Hart SN, Polley EC, Yadav S, Boddicker NJ, Samara R, Xia L, Sheng X, Lubmawa A, Kiddu V, et al. Pathogenic Variants in Cancer Predisposition Genes and Prostate Cancer Risk in Men of African Ancestry. Jco Precision Oncology. 4: 32-43. PMID 32832836 DOI: 10.1200/po.19.00179  0.18
2021 Gu J, Polley EC, Boughey JC, Fazzio RT, Fatemi M, Alizad A. Prediction of Invasive Breast Cancer Using Mass Characteristic Frequency and Elasticity in Correlation with Prognostic Histologic Features and Immunohistochemical Biomarkers. Ultrasound in Medicine & Biology. PMID 33994231 DOI: 10.1016/j.ultrasmedbio.2021.03.039  0.178
2021 Wallach JD, Deng Y, McCoy RG, Dhruva SS, Herrin J, Berkowitz A, Polley EC, Quinto K, Gandotra C, Crown W, Noseworthy P, Yao X, Shah ND, Ross JS, Lyon TD. Real-world Cardiovascular Outcomes Associated With Degarelix vs Leuprolide for Prostate Cancer Treatment. Jama Network Open. 4: e2130587. PMID 34677594 DOI: 10.1001/jamanetworkopen.2021.30587  0.16
2020 Yadav S, Kasi PM, Bamlet WR, Ho TP, Polley EC, Hu C, Hart SN, Rabe KG, Boddicker NJ, Gnanaolivu RD, Lee KY, Lindstrom T, Petersen GM, Couch FJ, McWilliams RR. Effect of germline mutations in homologous recombination repair genes on overall survival of patients with pancreatic adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33028596 DOI: 10.1158/1078-0432.CCR-20-1788  0.155
2022 Ternifi R, Wang Y, Gu J, Polley EC, Carter JM, Pruthi S, Boughey JC, Fazzio RT, Fatemi M, Alizad A. Ultrasound high-definition microvasculature imaging with novel quantitative biomarkers improves breast cancer detection accuracy. European Radiology. PMID 35486168 DOI: 10.1007/s00330-022-08815-2  0.154
2022 Lowry KP, Geuzinge HA, Stout NK, Alagoz O, Hampton J, Kerlikowske K, de Koning HJ, Miglioretti DL, van Ravesteyn NT, Schechter C, Sprague BL, Tosteson ANA, Trentham-Dietz A, Weaver D, Yaffe MJ, ... ... Polley EC, et al. Breast Cancer Screening Strategies for Women With ATM, CHEK2, and PALB2 Pathogenic Variants: A Comparative Modeling Analysis. Jama Oncology. PMID 35175286 DOI: 10.1001/jamaoncol.2021.6204  0.137
2023 Ngufor C, Yao X, Inselman JW, Ross JS, Dhruva SS, Graham DJ, Lee JY, Siontis KC, Desai NR, Polley E, Shah ND, Noseworthy PA. Identifying treatment heterogeneity in atrial fibrillation using a novel causal machine learning method. American Heart Journal. PMID 36893934 DOI: 10.1016/j.ahj.2023.02.015  0.126
2020 Gu J, Polley EC, Ternifi R, Nayak R, Boughey JC, Fazzio RT, Fatemi M, Alizad A. Individualized-thresholding Shear Wave Elastography combined with clinical factors improves specificity in discriminating breast masses. Breast (Edinburgh, Scotland). 54: 248-255. PMID 33188991 DOI: 10.1016/j.breast.2020.10.013  0.121
2022 Deng Y, Polley EC, Wallach JD, Dhruva SS, Herrin J, Quinto K, Gandotra C, Crown W, Noseworthy P, Yao X, Lyon TD, Shah ND, Ross JS, McCoy RG. Emulating the GRADE trial using real world data: retrospective comparative effectiveness study. Bmj (Clinical Research Ed.). 379: e070717. PMID 36191949 DOI: 10.1136/bmj-2022-070717  0.108
2021 Jo JH, Harkins CP, Schwardt NH, Portillo JA, Zimmerman MD, Carter CL, Hossen MA, Peer CJ, Polley EC, Dartois V, Figg WD, Moutsopoulos NM, Segre JA, Kong HH. Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics. Science Translational Medicine. 13: eabd8077. PMID 34936382 DOI: 10.1126/scitranslmed.abd8077  0.099
2023 Deng Y, Polley EC, Wallach JD, Herrin J, Ross JS, McCoy RG. Comparative effectiveness of second line glucose lowering drug treatments using real world data: emulation of a target trial. Bmj Medicine. 2: e000419. PMID 37577025 DOI: 10.1136/bmjmed-2022-000419  0.099
2023 Wallach JD, Deng Y, Polley EC, Dhruva SS, Herrin J, Quinto K, Gandotra C, Crown W, Noseworthy P, Yao X, Jeffery MM, Lyon TD, Ross JS, McCoy RG. Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials. Clinical Trials (London, England). 17407745231193137. PMID 37589143 DOI: 10.1177/17407745231193137  0.094
2021 Webb JM, Meixner DD, Adusei SA, Polley EC, Fatemi M, Alizad A. Automatic Deep Learning Semantic Segmentation of Ultrasound Thyroid Cineclips Using Recurrent Fully Convolutional Networks. Ieee Access : Practical Innovations, Open Solutions. 9: 5119-5127. PMID 33747681 DOI: 10.1109/access.2020.3045906  0.084
2023 Jain RK, Weiner M, Polley E, Iwamaye A, Huang E, Vokes T. Electronic Health Records (EHRs) Can Identify Patients at High Risk of Fracture but Require Substantial Race Adjustments to Currently Available Fracture Risk Calculators. Journal of General Internal Medicine. PMID 37715097 DOI: 10.1007/s11606-023-08347-5  0.081
2023 Didier NA, King AC, Polley EC, Fridberg DJ. Signal processing and machine learning with transdermal alcohol concentration to predict natural environment alcohol consumption. Experimental and Clinical Psychopharmacology. PMID 37824232 DOI: 10.1037/pha0000683  0.069
2020 Liu HC, Abbasi M, Ding YH, Polley EC, Fitzgerald S, Kadirvel R, Kallmes DF, Brinjikji W, Urban MW. Characterizing thrombus with multiple red blood cell compositions by optical coherence tomography attenuation coefficient. Journal of Biophotonics. PMID 33314731 DOI: 10.1002/jbio.202000364  0.069
2023 Issa NP, Aydin S, Bhatnagar S, Baumgartner NW, Hill J, Aluri S, Valentic CS, Polley E, Gomez CM, Rezania K. Intermuscular Coherence in Spinocerebellar Ataxias 3 and 6: a Preliminary Study. Cerebellum (London, England). PMID 37428409 DOI: 10.1007/s12311-023-01585-7  0.068
2021 Adusei SA, Gregory AV, Polley EC, Alizad A, Fatemi M. Does Body Position Affect Ultrasound Measurements of Bladder-Wall Elasticity? Ultrasound in Medicine & Biology. PMID 33446373 DOI: 10.1016/j.ultrasmedbio.2020.12.016  0.065
2021 Brinjikji W, Nogueira RG, Kvamme P, Layton KF, Delgado Almandoz JE, Hanel RA, Mendes Pereira V, Almekhlafi MA, Yoo AJ, Jahromi BS, Gounis MJ, Patel B, Abbasi M, Fitzgerald S, Mereuta OM, ... ... Polley EC, et al. Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology. Journal of Neurointerventional Surgery. PMID 33722963 DOI: 10.1136/neurintsurg-2020-017167  0.062
2022 Olson EM, Falde SD, Wegehaupt AK, Polley E, Halvorsen AJ, Lawson DK, Ratelle JT. Dismissal disagreement and discharge delays: Associations of patient-clinician plan of care agreement with discharge outcomes. Journal of Hospital Medicine. PMID 35942985 DOI: 10.1002/jhm.12929  0.057
2006 Spielman SE, Golembeski CA, Northridge ME, Vaughan RD, Swaner R, Jean-Louis B, Shoemaker K, Klihr-Beall S, Polley E, Cushman LF, Ortiz B, Hutchinson VE, Nicholas SW, Marx T, Hayes R, et al. Interdisciplinary Planning for Healthier Communities: Findings from the Harlem Children's Zone Asthma Initiative Journal of the American Planning Association. 72: 100-108. DOI: 10.1080/01944360608976727  0.053
2021 Panda A, Korfiatis P, Suman G, Garg SK, Polley EC, Singh DP, Chari ST, Goenka AH. A Two-Stage Deep Learning Model for Fully Automated Pancreas Segmentation on Computed Tomography: Comparison with Intra-Reader and Inter-Reader Reliability at Full and Reduced Radiation Dose on an External Dataset. Medical Physics. PMID 33595105 DOI: 10.1002/mp.14782  0.052
2023 Nogueira RG, Pinheiro A, Brinjikji W, Abbasi M, Al-Bayati AR, Mohammaden MH, Souza Viana L, Ferreira F, Abdelhamid H, Bhatt NR, Kvamme P, Layton KF, Delgado Almandoz JE, Hanel RA, Mendes Pereira V, ... ... Polley EC, et al. Clot composition and recanalization outcomes in mechanical thrombectomy. Journal of Neurointerventional Surgery. PMID 37419694 DOI: 10.1136/jnis-2023-020117  0.05
2021 Ratelle JT, Herberts M, Miller D, Kumbamu A, Lawson D, Polley E, Beckman TJ. Relationships Between Time-at-Bedside During Hospital Ward Rounds, Clinician-Patient Agreement, and Patient Experience. Journal of Patient Experience. 8: 23743735211008303. PMID 34179432 DOI: 10.1177/23743735211008303  0.049
2021 Kunz HE, Hart CR, Gries KJ, Parvizi M, Laurenti MC, Dalla Man C, Moore N, Zhang X, Ryan Z, Polley EC, Jensen MD, Vella A, Lanza IR. Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity. American Journal of Physiology. Endocrinology and Metabolism. PMID 33998291 DOI: 10.1152/ajpendo.00070.2021  0.044
2021 Zhang X, Kunz HE, Gries K, Hart CR, Polley EC, Lanza IR. Preserved skeletal muscle oxidative capacity in older adults despite decreased cardiorespiratory fitness with aging. The Journal of Physiology. PMID 34032280 DOI: 10.1113/JP281691  0.03
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