Paul S. Meltzer - Publications

Affiliations: 
The George Washington University, Washington, DC, United States 
Area:
Molecular Biology, Oncology

378 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lazar SB, Pongor L, Li XL, Grammatikakis I, Muys BR, Dangelmaier EA, Redon CE, Jang SM, Walker RL, Tang W, Ambs S, Harris CC, Meltzer PS, Aladjem MI, Lal A. Genome-wide analysis of the FOXA1 transcriptional network identifies novel protein-coding and lncRNA targets in colorectal cancer cells. Molecular and Cellular Biology. PMID 32839292 DOI: 10.1128/Mcb.00224-20  0.389
2020 Krushkal J, Silvers T, Reinhold WC, Sonkin D, Vural S, Connelly J, Varma S, Meltzer PS, Kunkel M, Rapisarda A, Evans D, Pommier Y, Teicher BA. Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets. Clinical Epigenetics. 12: 93. PMID 32586373 DOI: 10.1186/S13148-020-00876-8  0.352
2020 Wei D, Yang Y, Ricketts CJ, Vocke CD, Ball M, Sourbier C, Wangsa D, Wangsa D, Guha R, Zhang X, Wilson K, Chen L, Meltzer PS, Ried T, Thomas CJ, et al. Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments. Genes, Chromosomes & Cancer. PMID 32259323 DOI: 10.1002/Gcc.22847  0.332
2020 Chaudhary R, Muys BR, Grammatikakis I, De S, Abdelmohsen K, Li XL, Zhu Y, Daulatabad SV, Tsitsipatis D, Meltzer PS, Gorospe M, Janga SC, Lal A. A circular RNA from the locus controls cell cycle progression by suppressing p53 levels. Molecular and Cellular Biology. PMID 32041821 DOI: 10.1128/Mcb.00473-19  0.311
2020 Arons E, Zhou H, Sokolsky M, Gorelik D, Potocka K, Davies S, Fykes E, Still K, Edelman DC, Wang Y, Meltzer PS, Raffeld M, Wiestner A, Xi L, Wang HW, et al. Expression of the muscle-associated gene MYF6 in hairy cell leukemia. Plos One. 15: e0227586. PMID 32040482 DOI: 10.1371/Journal.Pone.0227586  0.337
2020 Au WC, Zhang T, Mishra PK, Eisenstatt JR, Walker RL, Ocampo J, Dawson A, Warren J, Costanzo M, Baryshnikova A, Flick K, Clark DJ, Meltzer PS, Baker RE, Myers C, et al. Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast. Plos Genetics. 16: e1008597. PMID 32032354 DOI: 10.1371/Journal.Pgen.1008597  0.34
2020 Brodie SA, Rodriguez-Aulet JP, Giri N, Dai J, Steinberg M, J Waterfall J, Roberson D, Ballew BJ, Zhou W, Anzick SL, Jiang Y, Wang Y, Zhu YJ, Meltzer PS, Boland J, et al. Corrigendum: 1q21.1 deletion and a rare functional polymorphism in siblings with thrombocytopenia-absent radius-like phenotypes. Cold Spring Harbor Molecular Case Studies. 6. PMID 32014861 DOI: 10.1101/mcs.a005116  0.624
2020 Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, ... ... Meltzer PS, et al. Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis. Nature Communications. 11: 333. PMID 31949145 DOI: 10.1038/S41467-019-14085-2  0.39
2020 Wedekind MF, Del Rivero J, Arnaldez FI, Srinivasan R, Spencer M, Steinberg SM, Peer CJ, Figg WD, Killian JK, Meltzer PS, Linehan WM, Widemann BC, Glod J. A phase II trial of the DNA methyl transferase inhibitor, SGI-110 (Guadecitabine), in children and adults with SDH-deficient GIST, pheochromocytoma, and paraganglioma, and HLRCC-associated kidney cancer. Journal of Clinical Oncology. 38: 11540-11540. DOI: 10.1200/Jco.2020.38.15_Suppl.11540  0.307
2019 Mitchell KA, Nichols N, Tang W, Walling J, Stevenson H, Pineda M, Stefanescu R, Edelman DC, Girvin AT, Zingone A, Sinha S, Bowman E, Rossi EL, Arauz RF, Jack Zhu Y, ... ... Meltzer P, et al. Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans. Nature Communications. 10: 5735. PMID 31844068 DOI: 10.1038/S41467-019-13732-Y  0.301
2019 Brodie SA, Rodriguez-Aulet JP, Giri N, Dai J, Steinberg M, Waterfall JP, Roberson D, Ballew BJ, Zhou W, Anzick SL, Jiang Y, Wang Y, Zhu YJ, Meltzer PS, Boland J, et al. 1q21.1 deletion and a rare functional polymorphism in siblings with thrombocytopenia-absent radius-like phenotypes. Cold Spring Harbor Molecular Case Studies. 5. PMID 31836590 DOI: 10.1101/mcs.a004564  0.653
2019 Dalgleish JL, Wang Y, Zhu J, Meltzer PS. CNVScope: Visually Exploring Copy Number Aberrations in Cancer Genomes. Cancer Informatics. 18: 1176935119890290. PMID 31832011 DOI: 10.1177/1176935119890290  0.317
2019 Yin M, Baslan T, Walker RL, Zhu YJ, Freeland A, Matsukawa T, Sridharan S, Nussenzweig A, Pruitt SC, Lowe SW, Meltzer PS, Aplan PD. A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia. Jci Insight. PMID 31622281 DOI: 10.1172/Jci.Insight.131434  0.332
2019 Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabello L, ... ... Meltzer PS, et al. Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group. Cancer. PMID 31355930 DOI: 10.1002/Cncr.32351  0.315
2019 Reinhold WC, Varma S, Sunshine M, Elloumi F, Ofori-Atta K, Lee S, Trepel JB, Meltzer PS, Doroshow JH, Pommier Y. RNA sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB. Cancer Research. PMID 31113817 DOI: 10.1158/0008-5472.Can-18-2047  0.414
2019 Yost KE, Clatterbuck Soper SF, Walker RL, Pineda MA, Zhu YJ, Ester CD, Showman S, Roschke AV, Waterfall JJ, Meltzer PS. Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. Scientific Reports. 9: 4544. PMID 30872698 DOI: 10.1038/S41598-019-41058-8  0.359
2019 Tirosh A, Killian JK, Zhu YJ, Petersen D, Walling J, Mor-Cohen R, Neychev V, Stevenson H, Keutgen XM, Patel D, Nilubol N, Meltzer P, Kebebew E. ONCOGENE PANEL SEQUENCING ANALYSIS IDENTIFIES CANDIDATE ACTIONABLE GENES IN ADVANCED WELL-DIFFERENTIATED GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. PMID 30865533 DOI: 10.4158/Ep-2018-0603  0.371
2019 Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, et al. Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion. Journal of the National Cancer Institute. PMID 30698726 DOI: 10.1093/Jnci/Djy209  0.311
2019 Ilanchezhian M, Fuller SN, Raygada M, Stratakis CA, Meltzer PS, Miettinen M, Glod J, Killian K, Arnaldez FI. Clinical characterization of patients with SDHC epimutation in gastrointestinal stromal tumors. Journal of Clinical Oncology. 37: 11033-11033. DOI: 10.1200/Jco.2019.37.15_Suppl.11033  0.367
2019 Krushkal J, Silvers T, Sonkin D, Vural S, Connelly J, Varma S, Meltzer PS, Reinhold WC, Rapisarda A, Evans D, Pommier Y, Teicher BA. Abstract B013: Associations of epigenome-wide DNA methylation patterns with chemosensitivity and chemoresistance of small cell lung cancer cell lines Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B013  0.367
2018 Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG. Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma. International Journal of Cancer. PMID 30565669 DOI: 10.1002/Ijc.32006  0.361
2018 Karzai F, VanderWeele D, Madan RA, Owens H, Cordes LM, Hankin A, Couvillon A, Nichols E, Bilusic M, Beshiri ML, Kelly K, Krishnasamy V, Lee S, Lee MJ, Yuno A, ... ... Meltzer PS, et al. Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations. Journal For Immunotherapy of Cancer. 6: 141. PMID 30514390 DOI: 10.1186/S40425-018-0463-2  0.322
2018 Vocke CD, Ricketts CJ, Ball MW, Schmidt LS, Metwalli AR, Middelton LA, Killian JK, Khan J, Meltzer PS, Simonds WF, Merino MJ, Linehan WM. CDC73 germline mutation in a family with mixed epithelial and stromal tumors. Urology. PMID 30452964 DOI: 10.1016/J.Urology.2018.11.013  0.307
2018 Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, ... ... Meltzer PS, et al. Interaction between the microbiome and TP53 in human lung cancer. Genome Biology. 19: 123. PMID 30143034 DOI: 10.1186/S13059-018-1501-6  0.312
2018 Ciftci-Yilmaz S, Au WC, Mishra PK, Eisenstatt JR, Chang J, Dawson AR, Zhu I, Rahman M, Bilke S, Costanzo M, Baryshnikova A, Myers CL, Meltzer PS, Landsman D, Baker RE, et al. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Genetics. PMID 30012561 DOI: 10.1534/Genetics.118.301305  0.35
2018 Quan XX, Voong Hawk N, Chen W, Coupar J, Lee S, Petersen DW, Meltzer PS, Montemarano A, Braun M, Chen Z, Van Waes C. Targeting Notch1 and IKKa enhanced NF-κB activation in CD133 Skin Cancer Stem Cells. Molecular Cancer Therapeutics. PMID 29959199 DOI: 10.1158/1535-7163.Mct-17-0421  0.325
2018 Moreno-Smith M, Halder JB, Meltzer PS, Gonda TA, Mangala LS, Rupaimoole R, Lu C, Nagaraja AS, Gharpure KM, Kang Y, Rodriguez-Aguayo C, Vivas-Mejia PE, Zand B, Schmandt R, Wang H, et al. ATP11B mediates platinum resistance in ovarian cancer. The Journal of Clinical Investigation. PMID 29809169 DOI: 10.1172/Jci122301  0.353
2018 Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson H, Reardon E, McLoughlin KC, Kaufman A, Payabyab E, Hong JA, ... ... Meltzer PS, et al. Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model. Annals of the American Thoracic Society. 15: S127-S128. PMID 29676638 DOI: 10.1513/Annalsats.201707-610Mg  0.321
2018 Kouprina N, Liskovykh M, Lee NCO, Noskov VN, Waterfall JJ, Walker RL, Meltzer PS, Topol EJ, Larionov V. Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient. Oncotarget. 9: 15275-15291. PMID 29632643 DOI: 10.18632/Oncotarget.24567  0.334
2018 Sourbier C, Liao PJ, Ricketts CJ, Wei D, Yang Y, Baranes SM, Gibbs BK, Ohanjanian L, Spencer Krane L, Scroggins BT, Keith Killian J, Wei MH, Kijima T, Meltzer PS, Citrin DE, et al. Targeting loss of the Hippo signaling pathway in-deficient papillary kidney cancers. Oncotarget. 9: 10723-10733. PMID 29535838 DOI: 10.18632/Oncotarget.24112  0.363
2018 Waterfall JJ, Meltzer PS. A Non-canonical Polycomb Dependency in Synovial Sarcoma. Cancer Cell. 33: 344-346. PMID 29533779 DOI: 10.1016/J.Ccell.2018.02.013  0.318
2018 Ma X, Liu Y, Liu Y, Alexandrov LB, Edmonson MN, Gawad C, Zhou X, Li Y, Rusch MC, Easton J, Huether R, Gonzalez-Pena V, Wilkinson MR, Hermida LC, Davis S, ... ... Meltzer PS, et al. Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. Nature. PMID 29489755 DOI: 10.1038/Nature25795  0.4
2018 Morrow JJ, Bayles I, Funnell APW, Miller TE, Saiakhova A, Lizardo MM, Bartels CF, Kapteijn MY, Hung S, Mendoza A, Dhillon G, Chee DR, Myers JT, Allen F, Gambarotti M, ... ... Meltzer PS, et al. Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. Nature Medicine. PMID 29334376 DOI: 10.1038/Nm.4475  0.394
2018 Yin M, Chung YJ, Lindsley RC, Zhu Y, Walker RL, Ebert BL, Meltzer PS, Aplan PD. Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background Blood. 132: 1331-1331. DOI: 10.1182/Blood-2018-99-115388  0.33
2018 Byun JS, Yan T, Sowalsky A, Zhu J, Meltzer P, Vohra N, Kragel P, Napoles A, Perez-Stable E, Gardner K. Abstract 4246: Characterizing breast cancer health disparities through molecular and genomic profiling of a diverse breast cancer cohort Cancer Research. 78: 4246-4246. DOI: 10.1158/1538-7445.Am2018-4246  0.343
2018 Edelman DC, Shebl F, Wang Y, Stevenson H, Sternberg L, Sampson J, Yang B, Meltzer PS, McGlynn K. Abstract 2633: The effects of aberrant global methylation in hepatocellular carcinoma Cancer Research. 78: 2633-2633. DOI: 10.1158/1538-7445.Am2018-2633  0.327
2018 Soper SFC, Yost KE, Walker RL, Pineda MA, Zhu YJ, Waterfall JJ, Meltzer PS. Abstract 1466: DAXX localizes ATRX to suppress alternative lengthening of telomeres in osteosarcoma Cancer Research. 78: 1466-1466. DOI: 10.1158/1538-7445.Am2018-1466  0.39
2018 Lee JS, Das A, Jerby-Arnon L, Arafeh R, Davidson M, Amzallag A, Park SG, Cheng K, Robinson W, Atias D, Stossel C, Buzhor E, Stein G, Waterfall JJ, Meltzer PS, et al. Abstract A188: Harnessing synthetic lethality to predict the response to cancer treatments Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A188  0.37
2017 Shell J, Patel D, Powers A, Quezado M, Killian K, Meltzer P, Zhu J, Gaitanidis A, Karzai F, Neychev V, Green P, Kebebew E. Somatic VHL Mutation in a Patient With MEN1-Associated Metastatic Pancreatic Neuroendocrine Tumor Responding to Sunitinib Treatment: A Case Report. Journal of the Endocrine Society. 1: 1124-1134. PMID 29264567 DOI: 10.1210/Js.2017-00156  0.354
2017 Oltmann J, Heselmeyer-Haddad K, Hernandez LS, Meyer R, Torres I, Hu Y, Doberstein N, Killian JK, Petersen D, Zhu YJ, Edelman DC, Meltzer PS, Schwartz R, Gertz EM, Schäffer AA, et al. Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients. Genes, Chromosomes & Cancer. PMID 29181861 DOI: 10.1002/Gcc.22515  0.397
2017 Rozenblum E, Sotelo-Silveira JR, Kim GY, Zhu JY, Lau CC, McNeil N, Korolevich S, Liao H, Cherry JM, Munroe DJ, Ried T, Meltzer PS, Kuehl WM, Roschke AV. Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor. Plos One. 12: e0182610. PMID 28787462 DOI: 10.1371/Journal.Pone.0182610  0.448
2017 Yang Y, Vocke CD, Ricketts CJ, Wei D, Padilla-Nash HM, Lang M, Sourbier C, Killian JK, Boyle SL, Worrell R, Meltzer PS, Ried T, Merino MJ, Metwalli AR, Linehan WM. Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276). Genes, Chromosomes & Cancer. PMID 28736828 DOI: 10.1002/Gcc.22476  0.372
2017 Enomoto K, Zhu X, Park S, Zhao L, Zhu YJ, Willingham MC, Qi J, Copland JA, Meltzer P, Cheng SY. Targeting MYC as a therapeutic intervention for anaplastic thyroid cancer. The Journal of Clinical Endocrinology and Metabolism. PMID 28368473 DOI: 10.1210/Jc.2016-3771  0.358
2017 Kummar S, O'Sullivan Coyne G, Do KT, Turkbey B, Meltzer PS, Polley E, Choyke PL, Meehan R, Vilimas R, Horneffer Y, Juwara L, Lih A, Choudhary A, Mitchell SA, Helman LJ, et al. Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016711994. PMID 28350521 DOI: 10.1200/Jco.2016.71.1994  0.312
2017 Goldberg L, Gough SM, Lee F, Dang C, Walker RL, Zhu YJ, Bilke S, Pineda M, Onozawa M, Chung YJ, Meltzer PS, Aplan PD. Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance. Genes, Chromosomes & Cancer. PMID 28196408 DOI: 10.1002/Gcc.22451  0.392
2017 Greathouse L, White J, Bliskovsky V, Vargas A, Polley E, Bowman E, Khan M, Robles A, Ryan B, Dzutsev A, Trinchieri G, Pineda M, Bilke S, Meltzer P, Walther-Antonio M, et al. Abstract 4925: Microbiome-TP53 gene interaction in human lung cancer Cancer Research. 77: 4925-4925. DOI: 10.1158/1538-7445.Am2017-4925  0.345
2017 Kraft IL, Akshintala S, Killian KJ, Hufnagel RB, Glod JW, Derse-Anthony C, Zhu Y, Stevenson HS, Bradford D, Merino MJ, Balis FM, Fox E, Widemann BC, Shern JF, Meltzer PS. Abstract 4882: Genomic mechanisms of disease progression in pediatric medullary thyroid cancer (MTC) Cancer Research. 77: 4882-4882. DOI: 10.1158/1538-7445.Am2017-4882  0.307
2017 Edelman DC, Stevenson HS, Wang Y, Arons E, Waterfall JJ, Petersen D, Zhou H, Meltzer PS, Kreitman RJ. Abstract 4682: Genomic profiles in gene expression and methylation help define the molecular characteristics of hairy cell leukemia subtypes Cancer Research. 77: 4682-4682. DOI: 10.1158/1538-7445.Am2017-4682  0.37
2017 Budhu A, Chaisaingmongkol J, Dang H, Rabibhadana S, Pupacdi B, Kwon SM, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul CU, Sricharunrat T, Phornphutkul K, ... ... Meltzer PS, et al. Abstract 4390: The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identified by integrated genomics Cancer Research. 77: 4390-4390. DOI: 10.1158/1538-7445.Am2017-4390  0.338
2017 Soper SFC, Showman SA, Driest KE, Waterfall JJ, Walker RL, Pineda MA, Zhu YJ, Wang Y, Ester CD, Bilke S, Meltzer PS. Abstract 3467: A DAXX-KIFC3 fusion potentiates alternative lengthening of telomeres in osteosarcoma Cancer Research. 77: 3467-3467. DOI: 10.1158/1538-7445.Am2017-3467  0.385
2017 Ma X, Liu Y, Liu Y, Edmonson M, Gawad C, Zhou X, Li Y, Rusch M, Easton J, Wilkinson M, Hermida LC, Davis S, Smith M, Auvil JG, Meltzer P, et al. Abstract 3004: Comparison of somatic alterations in the genome and transcriptome of 1,705 pediatric leukemia and solid tumors: a report from the Children’s Oncology Group (COG) - NCI TARGET Project Cancer Research. 77: 3004-3004. DOI: 10.1158/1538-7445.Am2017-3004  0.419
2017 Hirsch DD, Wangsa D, Hu Y, Zhu J, Petersen D, Edelman DC, Meltzer PS, Tran B, Heselmeyer-Haddad K, Ried T, Gaiser T. Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis Cancer Research. 77: 1438-1438. DOI: 10.1158/1538-7445.Am2017-1438  0.358
2017 Biswas R, Gao S, Cultraro C, Zhang X, Maity T, Carter C, Thomas A, Rajan A, Hanada K, Song Y, Abdullaev Z, Meltzer P, Yang J, Pack S, Giaccone G, et al. P2.01-041 Integrated Proteo-Genomics Analyses Reveal Extensive Tumor Heterogeneity and Novel Somatic Variants in Lung Adenocarcinoma: Topic: Proteins in Lung Cancer and Proteomics Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.1093  0.308
2016 Reinhold WC, Varma S, Sunshine M, Rajapakse V, Luna A, Kohn KW, Stevenson H, Wang Y, Heyn H, Nogales V, Moran S, Goldstein DJ, Doroshow JH, Meltzer PS, Esteller M, et al. The NCI-60 Methylome and its Integration into CellMiner. Cancer Research. PMID 27923837 DOI: 10.1158/0008-5472.Can-16-0655  0.396
2016 Killian JK, Dorssers LC, Trabert B, Gillis AJ, Cook MB, Wang Y, Waterfall JJ, Stevenson H, Smith WI, Noyes N, Retnakumar P, Stoop JH, Oosterhuis JW, Meltzer PS, McGlynn KA, et al. Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors. Genome Research. 26: 1490-1504. PMID 27803193 DOI: 10.1101/Gr.201293.115  0.316
2016 Canela A, Sridharan S, Sciascia N, Tubbs A, Meltzer P, Sleckman BP, Nussenzweig A. DNA Breaks and End Resection Measured Genome-wide by End Sequencing. Molecular Cell. PMID 27477910 DOI: 10.1016/J.Molcel.2016.06.034  0.318
2016 Zhu X, Enomoto K, Zhao L, Zhu YJ, Willingham MC, Meltzer PS, Qi J, Cheng SY. Bromodomain and extraterminal protein inhibitor JQ1 suppresses thyroid tumor growth in a mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27440272 DOI: 10.1158/1078-0432.Ccr-16-0914  0.33
2016 Si H, Lu H, Yang X, Mattox A, Jang M, Bian Y, Sano E, Viadiu H, Yan B, Yau C, Ng S, Lee SK, Romano RA, Davis S, Walker RL, ... ... Meltzer PS, et al. TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer. Oncogene. PMID 27132513 DOI: 10.1038/Onc.2016.112  0.387
2016 Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, et al. Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop. Cancer Genetics. PMID 27132463 DOI: 10.1016/J.Cancergen.2016.03.004  0.321
2016 Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, ... ... Meltzer PS, et al. Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics. PMID 27087319 DOI: 10.1016/J.Ajhg.2016.03.001  0.311
2016 Boikos SA, Pappo AS, Killian JK, LaQuaglia MP, Weldon CB, George S, Trent JC, von Mehren M, Wright JA, Schiffman JD, Raygada M, Pacak K, Meltzer PS, Miettinen MM, Stratakis C, et al. Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic. Jama Oncology. PMID 27011036 DOI: 10.1001/Jamaoncol.2016.0256  0.346
2016 Zhang H, Meltzer PS, Davis SR. caOmicsV: an R package for visualizing multidimensional cancer genomic data. Bmc Bioinformatics. 17: 141. PMID 27005934 DOI: 10.1186/S12859-016-0989-6  0.343
2016 Sorber R, Teper Y, Abisoye-Ogunniyan A, Waterfall JJ, Davis S, Killian JK, Pineda M, Ray S, McCord MR, Pflicke H, Burkett SS, Meltzer PS, Rudloff U. Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion. Plos One. 11: e0149833. PMID 26962861 DOI: 10.1371/Journal.Pone.0149833  0.387
2016 Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, ... ... Meltzer P, et al. The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget. PMID 26802024 DOI: 10.18632/Oncotarget.6937  0.332
2016 Neychev V, Sadowski SM, Zhu J, Allgaeuer M, Kilian K, Meltzer P, Kebebew E. Neuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case Report. The Journal of Clinical Endocrinology and Metabolism. 101: 353-358. PMID 26678657 DOI: 10.1210/Jc.2015-3684  0.381
2016 Krane LS, Railkar R, Hsu I, Vocke C, Meltzer PS, Thomas C, Ferrer M, Agarwal PK. High throughput screening to assess urothelial cancer lines and their metastatic derivatives for assessing changes in sensitivity in therapeutics. Journal of Clinical Oncology. 34: 407-407. DOI: 10.1200/Jco.2016.34.2_Suppl.407  0.335
2016 Arons E, Zhou H, Wang Y, Edelman D, Kreitman RJ, Stevenson HS, Waterfall JJ, Meltzer PS. Increased Expression of Myc in Hairy Cell Leukemia, and Cell-Sensitivity to JQ1 Blood. 128: 5112-5112. DOI: 10.1182/Blood.V128.22.5112.5112  0.333
2016 Bilke S, Meltzer PS. Abstract LB-291: Environment or accident? A more stringent bound on environmental contributions to cancerogenesis Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-291  0.321
2016 Morrow JJ, Miller TE, Saiakhova A, Lizardo MM, Bartels CF, Bayles I, Hung S, Mendoza A, Myers JT, Allen F, DiFeo A, Rubin BP, Huang AY, Meltzer PS, Helman LJ, et al. Abstract LB-151: Positively selected enhancer elements endow tumor cells with metastatic competence Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-151  0.401
2016 Yang B, Shebl FM, Sternberg LR, Warner AC, Kleiner DE, Edelman DC, Gomez A, Dagnall CL, Hicks BD, Altekruse SF, Hernandez BY, Lynch CF, Meltzer PS, McGlynn KA. Abstract 818: Shortened telomere length in hepatocellular carcinoma in the United States Cancer Research. 76: 818-818. DOI: 10.1158/1538-7445.Am2016-818  0.3
2016 Driest KE, Waterfall JJ, Walker RL, Pineda MA, Abaan O, Zhu YJ, Wang Y, Ester CD, Davis SR, Bilke S, Meltzer PS. Abstract 2717: Reintroduction of DAXX suppresses alternative lengthening of telomeres in osteosarcoma Cancer Research. 76: 2717-2717. DOI: 10.1158/1538-7445.Am2016-2717  0.397
2016 Ricketts C, Killian JK, Vocke CD, Sourbier C, Yang Y, Merino MJ, Meltzer PS, WML. Abstract 2660: A renal CpG island methylator phenotype (R-CIMP) in kidney tumors associated with germline mutations ofFHandSDHB Cancer Research. 76: 2660-2660. DOI: 10.1158/1538-7445.Am2016-2660  0.361
2016 Sun W, Chatterjee B, Shern JF, Wang Y, Stevenson HS, Edelman DC, Meltzer PS, Khan J, Barr FG. Abstract 2434: DNA methylation characterization of fusion-positive and fusion-negative rhabdomyosarcoma primary tumors and cell lines Cancer Research. 76: 2434-2434. DOI: 10.1158/1538-7445.Am2016-2434  0.352
2016 Ramirez LV, Bilke S, Walker R, Meltzer P, Qiu T, Rad R, Green JE. Abstract 1576: Insertional mutagenesis to identify molecular mechanisms of breast cancer dormancy and metastasis Cancer Research. 76: 1576-1576. DOI: 10.1158/1538-7445.Am2016-1576  0.414
2016 Krane L, Railkar R, Hsu I, Sidana A, Hammerich K, Vocke C, Meltzer P, Thomas C, Ferrer M, Agarwal P. Mp61-04 Alterations In Cell Line Sensitivity To Small Molecule Inhibitors Between Urothelial Cancer Lines And Their Metastatic Derivatives The Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.878  0.302
2015 Gara SK, Wang Y, Patel D, Chittenden YL, Jain M, Boufraqech M, Zhang L, Meltzer PS, Kebebew E. Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples. Nucleic Acids Research. PMID 26446994 DOI: 10.1093/Nar/Gkv908  0.392
2015 Ren L, Mendoza A, Zhu J, Briggs JW, Halsey C, Hong ES, Burkett SS, Morrow J, Lizardo MM, Osborne T, Li SQ, Luu HH, Meltzer P, Khanna C. Characterization of the metastatic phenotype of a panel of established osteosarcoma cells. Oncotarget. PMID 26320182 DOI: 10.18632/Oncotarget.5177  0.416
2015 Kang Z, Goldstein SD, Yu Y, Meltzer PS, Loeb DM, Cao L. Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma. British Journal of Cancer. PMID 26291055 DOI: 10.1038/Bjc.2015.298  0.302
2015 Torabi K, Miró R, Fernández-Jiménez N, Quintanilla I, Ramos L, Prat E, Del Rey J, Pujol N, Killian JK, Meltzer PS, Fernández PL, Ried T, Lozano JJ, Camps J, Ponsa I. Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer. Carcinogenesis. PMID 26243311 DOI: 10.1093/Carcin/Bgv115  0.421
2015 Sun W, Chatterjee B, Wang Y, Stevenson HS, Edelman DC, Meltzer PS, Barr FG. Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 1214-24. PMID 26226845 DOI: 10.1038/Modpathol.2015.82  0.343
2015 Robles AI, Arai E, Mathé EA, Okayama H, Schetter AJ, Brown D, Petersen D, Bowman ED, Noro R, Welsh JA, Edelman DC, Stevenson HS, Wang Y, Tsuchiya N, Kohno T, ... ... Meltzer PS, et al. An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1037-48. PMID 26134223 DOI: 10.1097/Jto.0000000000000560  0.303
2015 Mirabello L, Koster R, Moriarity BS, Spector LG, Meltzer PS, Gary J, Machiela MJ, Pankratz N, Panagiotou OA, Largaespada D, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Caminada de Toledo SR, et al. A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma. Cancer Discovery. PMID 26084801 DOI: 10.1158/2159-8290.Cd-15-0125  0.321
2015 Tang SW, Bilke S, Cao L, Murai J, Sousa FG, Yamade M, Rajapakse V, Varma S, Helman LJ, Khan J, Meltzer PS, Pommier Y. SLFN11 is a transcriptional target of EWS-FLI1 and a determinant of drug response in Ewing's sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25779942 DOI: 10.1158/1078-0432.Ccr-14-2112  0.35
2015 Figueroa JD, Yang H, Garcia-Closas M, Davis S, Meltzer P, Lissowska J, Horne HN, Sherman ME, Lee M. Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a methylation expression index (MEI) robustly associated with survival of ER-positive breast cancer patients. Breast Cancer Research and Treatment. 150: 457-66. PMID 25773928 DOI: 10.1007/S10549-015-3314-6  0.376
2015 Schwentner R, Papamarkou T, Kauer MO, Stathopoulos V, Yang F, Bilke S, Meltzer PS, Girolami M, Kovar H. EWS-FLI1 employs an E2F switch to drive target gene expression. Nucleic Acids Research. 43: 2780-9. PMID 25712098 DOI: 10.1093/Nar/Gkv123  0.34
2015 Waterfall JJ, Meltzer PS. Avalanching mutations in biallelic mismatch repair deficiency syndrome. Nature Genetics. 47: 194-6. PMID 25711864 DOI: 10.1038/Ng.3227  0.304
2015 Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, et al. Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1000-7. PMID 25667274 DOI: 10.1200/Jco.2014.58.2007  0.335
2015 Shakhova O, Cheng P, Mishra PJ, Zingg D, Schaefer SM, Debbache J, Häusel J, Matter C, Guo T, Davis S, Meltzer P, Mihic-Probst D, Moch H, Wegner M, Merlino G, et al. Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. Plos Genetics. 11: e1004877. PMID 25629959 DOI: 10.1371/Journal.Pgen.1004877  0.345
2015 Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, ... ... Meltzer PS, et al. A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis. Oncogene. 34: 1094-104. PMID 24662829 DOI: 10.1038/Onc.2014.46  0.347
2015 Kothari S, Gustafson D, Killian K, Costello J, Edelman DC, Walling J, Meltzer PS, Theodorescu D, Apolo AB. COXEN prediction of antineoplastic drug sensitivity in bladder cancer patients. Journal of Clinical Oncology. 33: 365-365. DOI: 10.1200/Jco.2016.34.2_Suppl.365  0.376
2015 Goldberg L, Pierce RM, Onozawa M, Walker RL, Zhu YJ, Meltzer PS, Aplan PD. Co-Expression of NUP98-HOXD13 and Mutant IDH2 Triggers an Early T-Cell Precursor-like Leukemia in Mice Blood. 126: 904-904. DOI: 10.1182/Blood.V126.23.904.904  0.381
2015 Bilke S, Meltzer P. Abstract LB-192: A single catastrophic genomic event is required for the development of osteosarcoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-192  0.353
2015 Chaisaingmongkol J, Budhu A, Dang H, Rabibhadana S, Pupacdi B, Forgues M, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul CU, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, ... ... Meltzer PS, et al. Abstract LB-173: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-173  0.322
2015 Edelman DC, Arons E, Stevenson H, Gomez A, Petersen D, Zhou H, Wang Y, Waterfall JJ, Meltzer PS, Kreitman R. Abstract 5307: Analysis of telomere length in classic and variant hairy cell leukemia Cancer Research. 75: 5307-5307. DOI: 10.1158/1538-7445.Am2015-5307  0.372
2015 Gao S, Cultraro C, BIswas R, Carter CA, Maity TK, Thomas A, Rajan A, Meltzer P, Schrump D, Giaccone G, Khan J, Guha U. Abstract 4759: Whole genome sequencing of sequentially acquired lung and lymph node metastatic sites from a never smoker lung adenocarcinoma patient revealed extensive genomic heterogeneity Cancer Research. 75: 4759-4759. DOI: 10.1158/1538-7445.Am2015-4759  0.322
2015 Kang Z, Shah A, Yu Y, Zhu Y, Bhagat AA, Zhao K, Wu A, Gao J, Madan R, Gulley J, Dahut W, Meltzer P, Cao L. Abstract 366: A novel transcript variant of androgen receptor identified in circulating tumor cells from castration-resistant prostate cancer patients as a potentially prognostic biomarker Cancer Research. 75: 366-366. DOI: 10.1158/1538-7445.Am2015-366  0.37
2015 Sun W, Chatterjee B, Wang Y, Stevenson HS, Edelman DC, Meltzer PS, Barr FG. Abstract 3278: Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma Cancer Research. 75: 3278-3278. DOI: 10.1158/1538-7445.Am2015-3278  0.367
2015 Kang Z, Goldstein DS, Yu Y, Meltzer PS, Loeb DM, Cao L. Abstract 2917: Caspase-8 expression is predictive of tumor response to death receptor 5 agonist antibody conatumumab in Ewing's sarcoma Cancer Research. 75: 2917-2917. DOI: 10.1158/1538-7445.Am2015-2917  0.328
2015 Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily M, Quist MJ, Davis L, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung T, Sun W, Kogiso M, ... ... Meltzer PS, et al. BT-02 * FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA Neuro-Oncology. 17: iii3-iii3. DOI: 10.1093/Neuonc/Nov061.12  0.303
2014 Killian JK, Miettinen M, Walker RL, Wang Y, Zhu YJ, Waterfall JJ, Noyes N, Retnakumar P, Yang Z, Smith WI, Killian MS, Lau CC, Pineda M, Walling J, Stevenson H, ... ... Meltzer PS, et al. Recurrent epimutation of SDHC in gastrointestinal stromal tumors. Science Translational Medicine. 6: 268ra177. PMID 25540324 DOI: 10.1126/Scitranslmed.3009961  0.411
2014 Waterfall JJ, Meltzer PS. Building through breaking: the development of cancer neochromosomes. Cancer Cell. 26: 593-5. PMID 25517741 DOI: 10.1016/J.Ccell.2014.10.013  0.354
2014 Li XL, Lu X, Parvathaneni S, Bilke S, Zhang H, Thangavel S, Vindigni A, Hara T, Zhu Y, Meltzer PS, Lal A, Sharma S. Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion. Cell Cycle (Georgetown, Tex.). 13: 2431-45. PMID 25483193 DOI: 10.4161/Cc.29419  0.451
2014 Wang Y, Thomas A, Lau C, Rajan A, Zhu Y, Killian JK, Petrini I, Pham T, Morrow B, Zhong X, Meltzer PS, Giaccone G. Mutations of epigenetic regulatory genes are common in thymic carcinomas. Scientific Reports. 4: 7336. PMID 25482724 DOI: 10.1038/Srep07336  0.356
2014 Waterfall JJ, Killian JK, Meltzer PS. The role of mutation of metabolism-related genes in genomic hypermethylation Biochemical and Biophysical Research Communications. 455: 16-23. PMID 25111818 DOI: 10.1016/J.Bbrc.2014.08.003  0.327
2014 Reinhold WC, Varma S, Sousa F, Sunshine M, Abaan OD, Davis SR, Reinhold SW, Kohn KW, Morris J, Meltzer PS, Doroshow JH, Pommier Y. NCI-60 whole exome sequencing and pharmacological CellMiner analyses. Plos One. 9: e101670. PMID 25032700 DOI: 10.1371/Journal.Pone.0101670  0.399
2014 Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, ... ... Meltzer PS, et al. Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes & Development. 28: 1578-91. PMID 25030697 DOI: 10.1101/Gad.238733.114  0.385
2014 Wang Z, Zhu B, Zhang M, Parikh H, Jia J, Chung CC, Sampson JN, Hoskins JW, Hutchinson A, Burdette L, Ibrahim A, Hautman C, Raj PS, Abnet CC, Adjei AA, ... ... Meltzer PS, et al. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Human Molecular Genetics. 23: 6616-33. PMID 25027329 DOI: 10.1093/Hmg/Ddu363  0.33
2014 Rotunno M, Sun X, Figueroa J, Sherman ME, Garcia-Closas M, Meltzer P, Williams T, Schneider SS, Jerry DJ, Yang XR, Troester MA. Parity-related molecular signatures and breast cancer subtypes by estrogen receptor status. Breast Cancer Research : Bcr. 16: R74. PMID 25005139 DOI: 10.1186/Bcr3689  0.321
2014 Petrini I, Meltzer PS, Kim IK, Lucchi M, Park KS, Fontanini G, Gao J, Zucali PA, Calabrese F, Favaretto A, Rea F, Rodriguez-Canales J, Walker RL, Pineda M, Zhu YJ, et al. A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. Nature Genetics. 46: 844-9. PMID 24974848 DOI: 10.1038/Ng.3016  0.367
2014 Khanna C, Fan TM, Gorlick R, Helman LJ, Kleinerman ES, Adamson PC, Houghton PJ, Tap WD, Welch DR, Steeg PS, Merlino G, Sorensen PH, Meltzer P, Kirsch DG, Janeway KA, et al. Toward a drug development path that targets metastatic progression in osteosarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4200-9. PMID 24803583 DOI: 10.1158/1078-0432.Ccr-13-2574  0.314
2014 Baysan M, Woolard K, Bozdag S, Riddick G, Kotliarova S, Cam MC, Belova GI, Ahn S, Zhang W, Song H, Walling J, Stevenson H, Meltzer P, Fine HA. Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells. Plos One. 9: e94045. PMID 24728236 DOI: 10.1371/Journal.Pone.0094045  0.335
2014 Gindin Y, Valenzuela MS, Aladjem MI, Meltzer PS, Bilke S. A chromatin structure-based model accurately predicts DNA replication timing in human cells. Molecular Systems Biology. 10: 722. PMID 24682507 DOI: 10.1002/Msb.134859  0.313
2014 Wentzensen N, Bakkum-Gamez JN, Killian JK, Sampson J, Guido R, Glass A, Adams L, Luhn P, Brinton LA, Rush B, d'Ambrosio L, Gunja M, Yang HP, Garcia-Closas M, Lacey JV, ... ... Meltzer P, et al. Discovery and validation of methylation markers for endometrial cancer. International Journal of Cancer. Journal International Du Cancer. 135: 1860-8. PMID 24623538 DOI: 10.1002/Ijc.28843  0.339
2014 Gough SM, Lee F, Yang F, Walker RL, Zhu YJ, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Xu B, Wang GG, Meltzer PS, et al. NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discovery. 4: 564-77. PMID 24535671 DOI: 10.1158/2159-8290.Cd-13-0419  0.318
2014 Ellis RJ, Wang Y, Stevenson HS, Boufraqech M, Patel D, Nilubol N, Davis S, Edelman DC, Merino MJ, He M, Zhang L, Meltzer PS, Kebebew E. Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype. The Journal of Clinical Endocrinology and Metabolism. 99: E329-37. PMID 24423287 DOI: 10.1210/Jc.2013-2749  0.32
2014 Gao R, Das BB, Chatterjee R, Abaan OD, Agama K, Matuo R, Vinson C, Meltzer PS, Pommier Y. Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel. Dna Repair. 13: 1-9. PMID 24355542 DOI: 10.1016/J.Dnarep.2013.09.001  0.377
2014 Terunuma A, Putluri N, Mishra P, Mathé EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, Stevenson HS, Karoly ED, Chan K, Samanta S, Prieto D, ... ... Meltzer PS, et al. MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. The Journal of Clinical Investigation. 124: 398-412. PMID 24316975 DOI: 10.1172/Jci71180  0.381
2014 Waterfall JJ, Arons E, Walker RL, Pineda M, Roth L, Killian JK, Abaan OD, Davis SR, Kreitman RJ, Meltzer PS. High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias. Nature Genetics. 46: 8-10. PMID 24241536 DOI: 10.1038/Ng.2828  0.334
2014 Wang Y, Meltzer PS, Lau C, Thomas A, Rajan A, Giaccone G. Recurrence of epigenetic gene mutations in thymic epithelial carcinomas revealed by targeted exome sequencing of cancer-associated genes. Journal of Clinical Oncology. 32: 7529-7529. DOI: 10.1200/Jco.2014.32.15_Suppl.7529  0.383
2014 Gough SM, Goldberg L, Pineda M, Walker RL, Zhu YJ, Bilke S, Meltzer PS, Aplan PD. Spontaneous Mutations of Bcor and Jak1/2 genes Lead to an Aggressive Leukemia of B-1 Progenitor B Cells Blood. 124: 3573-3573. DOI: 10.1182/Blood.V124.21.3573.3573  0.319
2014 Merlino GT, Day C, Mishra P, Guo T, Zaida R, Davis S, Meltzer P, Noonan F, Fabo ED, Ohler-Weaver Z, Dyke TV. Abstract IA22: Modeling recurrent metastatic melanoma in the mouse Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia22  0.4
2014 Mishra PJ, Guo T, Zaidi R, Davis S, Michalowski A, Michael H, Reinhold W, Arnheiter H, Meltzer P, Merlino G. Abstract 994: Integrated embryonic transcriptome analyses identify key melanoma metastasis regulator Cancer Research. 74: 994-994. DOI: 10.1158/1538-7445.Am2014-994  0.403
2014 Edelman DC, Petersen D, Gomez A, Gadalla S, Webster P, Dennis L, Krouse M, Savage S, Meltzer PS. Abstract 5100: Development of a direct-measurement molecular assay to determine telomere length in human samples Cancer Research. 74: 5100-5100. DOI: 10.1158/1538-7445.Am2014-5100  0.33
2014 Kang Z, Yu Y, Cao L, Meltzer PS, Zhu Y, Shah A, Gulley J, Duht W, Madan R, Bhagat A, Zhao K. Abstract 4815: A novel AR splice variant identified in circulating tumor cells from castration-resistant prostate cancer patient blood as a potentially prognostic biomarker Cancer Research. 74: 4815-4815. DOI: 10.1158/1538-7445.Am2014-4815  0.371
2014 Abaan OD, Waterfall J, Davis S, Edelman D, Gomez A, Savage S, Pommier Y, Meltzer P. Abstract 4167: Harvesting knowledge from unexploited genomic data: Estimating relative telomere length from targeted-resequencing Cancer Research. 74: 4167-4167. DOI: 10.1158/1538-7445.Am2014-4167  0.368
2014 Quan X, Voong N, Chen W, Coupar J, Lee S, Petersen DW, Edelman DC, Meltzer PS, Montemarano A, Braun M, Vogel J, Waes CV, Chen Z. Abstract 3019: Aberrant NF-κB and Notch pathways promote CD133+ cancer stem cells in human primary cutaneous squamous cell carcinoma Cancer Research. 74: 3019-3019. DOI: 10.1158/1538-7445.Am2014-3019  0.374
2014 Kang Z, Yu Y, Zhu YJ, Helman L, Meltzer P, Cao L. Abstract 1719: Down-regulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma Cancer Research. 74: 1719-1719. DOI: 10.1158/1538-7445.Am2014-1719  0.313
2014 Nogales V, Moutinho C, Martinez-Cardús A, Varma S, Killian JK, Reinhold WC, Meltzer PS, Pommier Y, Esteller M. Abstract 1366: Discovery of biomarkers for antitumor drug resistance using 450K methylation data of NCI60 Cancer Research. 74: 1366-1366. DOI: 10.1158/1538-7445.Am2014-1366  0.384
2013 Praetorius C, Grill C, Stacey SN, Metcalf AM, Gorkin DU, Robinson KC, Van Otterloo E, Kim RS, Bergsteinsdottir K, Ogmundsdottir MH, Magnusdottir E, Mishra PJ, Davis SR, Guo T, Zaidi MR, ... ... Meltzer PS, et al. A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell. 155: 1022-33. PMID 24267888 DOI: 10.1016/J.Cell.2013.10.022  0.331
2013 Webster LR, Provan PJ, Graham DJ, Byth K, Walker RL, Davis S, Salisbury EL, Morey AL, Ward RL, Hawkins NJ, Clarke CL, Meltzer PS, Balleine RL. Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33. Pathology. 45: 629-36. PMID 24247619 DOI: 10.1097/Pat.0000000000000004  0.404
2013 Trucco MM, Awad O, Wilky BA, Goldstein SD, Huang R, Walker RL, Shah P, Katuri V, Gul N, Zhu YJ, McCarthy EF, Paz-Priel I, Meltzer PS, Austin CP, Xia M, et al. A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology. Plos One. 8: e79950. PMID 24223206 DOI: 10.1371/Journal.Pone.0079950  0.338
2013 Bilke S, Schwentner R, Yang F, Kauer M, Jug G, Walker RL, Davis S, Zhu YJ, Pineda M, Meltzer PS, Kovar H. Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer. Genome Research. 23: 1797-809. PMID 23940108 DOI: 10.1101/Gr.151340.112  0.402
2013 Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology. Cancer Research. 73: 4372-82. PMID 23856246 DOI: 10.1158/0008-5472.Can-12-3342  0.408
2013 Klorin G, Rozenblum E, Glebov O, Walker RL, Park Y, Meltzer PS, Kirsch IR, Kaye FJ, Roschke AV. Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines Cancer Genetics. 206: 191-205. PMID 23830731 DOI: 10.1016/J.Cancergen.2013.04.006  0.401
2013 Savage SA, Mirabello L, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Flanagan AM, Tirabosco R, Andrulis IL, Wunder JS, Gokgoz N, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Kurucu N, ... ... Meltzer PS, et al. Genome-wide association study identifies two susceptibility loci for osteosarcoma. Nature Genetics. 45: 799-803. PMID 23727862 DOI: 10.1038/Ng.2645  0.319
2013 Kelly L, Bryan K, Kim SY, Janeway KA, Killian JK, Schildhaus HU, Miettinen M, Helman L, Meltzer PS, van de Rijn M, Debiec-Rychter M, O'Sullivan M. Post-Transcriptional Dysregulation by miRNAs Is Implicated in the Pathogenesis of Gastrointestinal Stromal Tumor [GIST] Plos One. 8. PMID 23717541 DOI: 10.1371/Journal.Pone.0064102  0.307
2013 Kim DW, Walker RL, Meltzer PS, Cheng SY. Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model. Carcinogenesis. 34: 2389-400. PMID 23698635 DOI: 10.1093/Carcin/Bgt175  0.385
2013 Tan X, Anzick SL, Khan SG, Ueda T, Stone G, Digiovanna JJ, Tamura D, Wattendorf D, Busch D, Brewer CC, Zalewski C, Butman JA, Griffith AJ, Meltzer PS, Kraemer KH. Chimeric negative regulation of p14ARF and TBX1 by a t(9;22) translocation associated with melanoma, deafness, and DNA repair deficiency. Human Mutation. 34: 1250-9. PMID 23661601 DOI: 10.1002/Humu.22354  0.707
2013 Teer JK, Johnston JJ, Anzick SL, Pineda M, Stone G, Meltzer PS, Mullikin JC, Biesecker LG. Massively-parallel sequencing of genes on a single chromosome: a comparison of solution hybrid selection and flow sorting. Bmc Genomics. 14: 253. PMID 23586822 DOI: 10.1186/1471-2164-14-253  0.669
2013 Killian JK, Kim SY, Miettinen M, Smith C, Merino M, Tsokos M, Quezado M, Smith WI, Jahromi MS, Xekouki P, Szarek E, Walker RL, Lasota J, Raffeld M, Klotzle B, ... ... Meltzer PS, et al. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discovery. 3: 648-57. PMID 23550148 DOI: 10.1158/2159-8290.Cd-13-0092  0.319
2013 Azad N, Yu M, Davidson B, Choyke P, Chen CC, Wood BJ, Venkatesan A, Henning R, Calvo K, Minasian L, Edelman DC, Meltzer P, Steinberg SM, Annunziata CM, Kohn EC. Translational predictive biomarker analysis of the phase 1b sorafenib and bevacizumab study expansion cohort. Molecular & Cellular Proteomics : McP. 12: 1621-31. PMID 23449826 DOI: 10.1074/Mcp.M112.026427  0.3
2013 Petrini I, Wang Y, Zucali PA, Lee HS, Pham T, Voeller D, Meltzer PS, Giaccone G. Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1960-71. PMID 23444221 DOI: 10.1158/1078-0432.Ccr-12-3260  0.42
2013 Miettinen M, Killian JK, Wang ZF, Lasota J, Lau C, Jones L, Walker R, Pineda M, Zhu YJ, Kim SY, Helman L, Meltzer P. Immunohistochemical loss of succinate dehydrogenase subunit a (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation American Journal of Surgical Pathology. 37: 234-240. PMID 23282968 DOI: 10.1097/Pas.0B013E3182671178  0.326
2013 Hirsch D, Kemmerling R, Davis S, Camps J, Meltzer PS, Ried T, Gaiser T. Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma. Cancer Research. 73: 1454-60. PMID 23271725 DOI: 10.1158/0008-5472.Can-12-0928  0.356
2013 Giaccone G, Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Duffy RM, Morrow B, Wang Y, Carter CA, Guha U, Killian K, Lau CY, Abdullaev Z, Xi L, Pack S, ... Meltzer PS, et al. Custom (Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies) trial. Journal of Clinical Oncology. 31: 7513-7513. DOI: 10.1200/Jco.2013.31.15_Suppl.7513  0.318
2013 Gough SM, Lee F, Walker RL, Yang F, Zhu Y, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Meltzer PS, Aplan PD. Leukemia Driven By a NUP98-Phd Domain Fusion Is Highly Sensitive To Disruption Of H3K4me3-Phd Domain Binding By a Small Molecule Inhibitor Blood. 122: 3759-3759. DOI: 10.1182/Blood.V122.21.3759.3759  0.32
2013 Robles AI, Okayama H, Kumar SA, Franklin Z, Bowman ED, Edelman D, Stevenson H, Petersen D, Mathé E, Kanai Y, Kohno T, Tsuchiya N, Meltzer P, Yokota J, Harris CC. Abstract A47: Epigenetic regulation of microRNAs in early stage lung adenocarcinoma Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A47  0.307
2013 Kang Z, Dahut W, Gulley J, Yu Y, Meltzer PS, Cao L. Abstract 736: Development of a novel circulating tumor cell technology for cancer predictive biomarker analysis. Cancer Research. 73: 736-736. DOI: 10.1158/1538-7445.Am2013-736  0.367
2013 Gindin Y, Meltzer PS, Bilke S. Abstract 5150: What is in control of DNA replication timing. Cancer Research. 73: 5150-5150. DOI: 10.1158/1538-7445.Am2013-5150  0.32
2013 Savage SA, Mirabello L, Wang Z, Gastier-Foster J, Gorlick R, Khanna C, Flanagan AM, Tirabosco R, Andrulis IL, Wunder J, Gokgoz N, Patino-Garcia A, Sierrasesumaga L, Lecanda F, Kurucu N, ... ... Meltzer P, et al. Abstract 4593: Genome-wide association study identifies novel loci associated with osteosarcoma. Cancer Research. 73: 4593-4593. DOI: 10.1158/1538-7445.Am2013-4593  0.338
2013 Gindin Y, Davis S, Walker RL, Zhu YJ, Bilke S, Sherman ME, Figueroa J, Meltzer PS. Abstract 4250: DNA methylation portraits of breast cancer in a population-based cohort. Cancer Research. 73: 4250-4250. DOI: 10.1158/1538-7445.Am2013-4250  0.371
2013 Rozenblum E, Klorin G, Glebov O, Walker RL, Park Y, Meltzer PS, Kirsch IR, Kaye FJ, Roschke AV. Abstract 4208: Integrated oligo aCGH and SKY analysis of genomic alterations in malignant mesothelioma cell lines. Cancer Research. 73: 4208-4208. DOI: 10.1158/1538-7445.Am2013-4208  0.379
2013 Gough SM, Lee F, Chung YJ, Walker RL, Yang F, Zhu J, Ning Y, Meltzer PS, Aplan PD. Abstract 3851: NUP98-PHF23 (NP23) binds H3K4me3 and causes a wide spectrum of leukemias, including AML, T-ALL, and pre-B1 ALL. Cancer Research. 73: 3851-3851. DOI: 10.1158/1538-7445.Am2013-3851  0.31
2013 Edelman DC, Petersen D, Gomez A, Canales G, Stevenson H, Meltzer PS. Abstract 3508: Measurement of telomere repeats in human cancer cell lines and tissues using a monochrome multiplex quantitative PCR assay. Cancer Research. 73: 3508-3508. DOI: 10.1158/1538-7445.Am2013-3508  0.402
2013 Reinhold WC, Sunshine M, Varma S, Liu H, Abaan O, Meltzer P, Morris J, Kohn K, Doroshow J, Pommier Y. Abstract 3177: Web-based access using CellMiner for gene expression, DNA copy number, microRNA transcript levels, variant status, drug activity, and their pattern comparisons for the NCI-60. Cancer Research. 73: 3177-3177. DOI: 10.1158/1538-7445.Am2013-3177  0.331
2013 Abaan OD, Francis P, Pineda M, Walker RL, Zhu YJ, Bilke S, Davis SR, Meltzer PS. Abstract 3147: Cancer-specific mutations in adult soft tissue sarcomas. Cancer Research. 73: 3147-3147. DOI: 10.1158/1538-7445.Am2013-3147  0.381
2013 Mishra PJ, Guo T, Zaidi R, Davis S, Arnheiter H, Reinhold WC, Meltzer P, Merlino G. Abstract 2994: Using embryonic melanoblast transcriptome analysis to identify novel mechanisms promoting metastatic melanoma. Cancer Research. 73: 2994-2994. DOI: 10.1158/1538-7445.Am2013-2994  0.415
2013 Meltzer PS, Killian JK, Kim SY, Miettinen M, Smith C, Tsokos M, Quezado M, Smith WI, Jahromi MS, Walker RL, Lasota J, Klotzle B, Wang Z, Jones L, Zhu Y, et al. Abstract 2963: Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Research. 73: 2963-2963. DOI: 10.1158/1538-7445.Am2013-2963  0.339
2012 Baysan M, Bozdag S, Cam MC, Kotliarova S, Ahn S, Walling J, Killian JK, Stevenson H, Meltzer P, Fine HA. G-cimp status prediction of glioblastoma samples using mRNA expression data. Plos One. 7: e47839. PMID 23139755 DOI: 10.1371/Journal.Pone.0047839  0.366
2012 Chatterjee R, Zhao J, He X, Shlyakhtenko A, Mann I, Waterfall JJ, Meltzer P, Sathyanarayana BK, FitzGerald PC, Vinson C. Overlapping ETS and CRE Motifs ((G/C)CGGAAGTGACGTCA) preferentially bound by GABPα and CREB proteins. G3 (Bethesda, Md.). 2: 1243-56. PMID 23050235 DOI: 10.1534/G3.112.004002  0.305
2012 Gartner JJ, Davis S, Wei X, Lin JC, Trivedi NS, Teer JK, Meltzer PS, Rosenberg SA, Samuels Y. Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma. Bmc Genomics. 13: 505. PMID 23006843 DOI: 10.1186/1471-2164-13-505  0.37
2012 Parker SC, Gartner J, Cardenas-Navia I, Wei X, Ozel Abaan H, Ajay SS, Hansen NF, Song L, Bhanot UK, Killian JK, Gindin Y, Walker RL, Meltzer PS, Mullikin JC, Furey TS, et al. Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes. Plos Genetics. 8: e1002871. PMID 22912592 DOI: 10.1371/Journal.Pgen.1002871  0.375
2012 Petrini I, Meltzer PS, Zucali PA, Luo J, Lee C, Santoro A, Lee HS, Killian KJ, Wang Y, Tsokos M, Roncalli M, Steinberg SM, Wang Y, Giaccone G. Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors. Cell Death & Disease. 3: e351. PMID 22825469 DOI: 10.1038/Cddis.2012.92  0.391
2012 Kouprina N, Lee NC, Pavlicek A, Samoshkin A, Kim JH, Lee HS, Varma S, Reinhold WC, Otstot J, Solomon G, Davis S, Meltzer PS, Schleutker J, Larionov V. Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families. Genes, Chromosomes & Cancer. 51: 933-48. PMID 22733720 DOI: 10.1002/Gcc.21977  0.36
2012 Beachy SH, Onozawa M, Chung YJ, Slape C, Bilke S, Francis P, Pineda M, Walker RL, Meltzer P, Aplan PD. Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma. Blood. 120: 1048-59. PMID 22723554 DOI: 10.1182/Blood-2012-01-401760  0.301
2012 Rechache NS, Wang Y, Stevenson HS, Killian JK, Edelman DC, Merino M, Zhang L, Nilubol N, Stratakis CA, Meltzer PS, Kebebew E. DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors. The Journal of Clinical Endocrinology and Metabolism. 97: E1004-13. PMID 22472567 DOI: 10.1210/Jc.2011-3298  0.304
2012 Waterfall JJ, Meltzer PS. Targeting epigenetic misregulation in synovial sarcoma. Cancer Cell. 21: 323-4. PMID 22439927 DOI: 10.1016/J.Ccr.2012.02.023  0.347
2012 Debbache J, Zaidi MR, Davis S, Guo T, Bismuth K, Wang X, Skuntz S, Maric D, Pickel J, Meltzer P, Merlino G, Arnheiter H. In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor Genetics. 191: 133-144. PMID 22367038 DOI: 10.1534/Genetics.111.135996  0.301
2012 Roessler S, Long EL, Budhu A, Chen Y, Zhao X, Ji J, Walker R, Jia HL, Ye QH, Qin LX, Tang ZY, He P, Hunter KW, Thorgeirsson SS, Meltzer PS, et al. Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival. Gastroenterology. 142: 957-966.e12. PMID 22202459 DOI: 10.1053/J.Gastro.2011.12.039  0.387
2012 Lee JH, Giovannetti E, Hwang JH, Petrini I, Wang Q, Voortman J, Wang Y, Steinberg SM, Funel N, Meltzer PS, Wang Y, Giaccone G. Loss of 18q22.3 involving the carboxypeptidase of glutamate-like gene is associated with poor prognosis in resected pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 524-33. PMID 22128300 DOI: 10.1158/1078-0432.Ccr-11-1903  0.419
2012 Warren KE, Killian K, Suuriniemi M, Wang Y, Quezado M, Meltzer PS. Genomic aberrations in pediatric diffuse intrinsic pontine gliomas. Neuro-Oncology. 14: 326-32. PMID 22064882 DOI: 10.1093/Neuonc/Nor190  0.383
2012 Valenzuela MS, Hu L, Lueders J, Walker R, Meltzer PS. Broader utilization of origins of DNA replication in cancer cell lines along a 78 kb region of human chromosome 2q34. Journal of Cellular Biochemistry. 113: 132-40. PMID 21898540 DOI: 10.1002/Jcb.23336  0.374
2012 Zoppoli G, Solier S, Reinhold WC, Liu H, Connelly JW, Monks A, Shoemaker RH, Abaan OD, Davis SR, Meltzer PS, Doroshow JH, Pommier Y. CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute Oncogene. 31: 403-418. PMID 21765476 DOI: 10.1038/Onc.2011.283  0.417
2012 Lopez-Chavez A, Rajan A, Thomas A, Raffeld M, Xi L, Meltzer PS, Duffy RM, Pack S, Sandler A, Corless CL, Killian K, Oberholtzer C, Abdullaev Z, Giaccone G. Pilot trial of molecular profiling and targeted therapies in advanced thoracic malignancies: Non-small cell lung cancer, small cell lung cancer and thymic malignancies (CUSTOM). Journal of Clinical Oncology. 30. DOI: 10.1200/Jco.2012.30.15_Suppl.Tps7609  0.332
2012 Moon SY, Bilke S, Davis S, Walker RL, Pineda M, Zhu YJ, Abaan O, Meltzer PS. Abstract 5070: Paired-end RNA-sequencing reveals novel fusion genes and SNVs in osteosarcoma Cancer Research. 72: 5070-5070. DOI: 10.1158/1538-7445.Am2012-5070  0.406
2012 Wentzensen NA, Killian K, Adams L, Luhn P, Kloor M, Guido R, Yang HP, Garcia-Closas M, Brinton L, d'Ambrosio L, Lissowska J, Hewitt S, Meltzer P, Sherman M. Abstract 5012: DNA methylation profiles of endometrial cancer and benign endometrium suggest differences by mismatch repair status and possible early detection markers Cancer Research. 72: 5012-5012. DOI: 10.1158/1538-7445.Am2012-5012  0.346
2012 Mishra PJ, Guo T, Zaidi R, Davis S, Arnheiter H, Walker RL, Meltzer P, Merlino G. Abstract 4856: Using embryonic melanoblast transcriptome analysis to identify novel mechanisms promoting metastatic melanoma Cancer Research. 72: 4856-4856. DOI: 10.1158/1538-7445.Am2012-4856  0.424
2012 Luhn P, Sherman M, Killian K, Adams L, Stevenson H, Meltzer P, D'Ambrosio L, Hewitt SM, Guido R, Wentzensen N. Abstract 4475: Association of endometrial cancer risk factors and DNA methylation in benign endometrial tissue Cancer Research. 72: 4475-4475. DOI: 10.1158/1538-7445.Am2012-4475  0.332
2012 Si H, Lu H, Yang X, Jang M, Burnett J, Davis S, Sun H, Xiao W, Wei L, Meltzer P, Waes CV, Chen Z. Abstract 4193: TNF-α dynamically modulates genome-wide cross-regulation of cRel, ΔNp63 and TAp73 promoter binding and gene expression in head and neck cancer: TP53 and NFκB ChIP-Seq in HNSCC Cancer Research. 72: 4193-4193. DOI: 10.1158/1538-7445.Am2012-4193  0.35
2012 Niedan S, Kauer M, Jug G, Walker RL, Meltzer PS, Kontny U, Kovar H. Abstract 2961: Reactivation of EWS-FLI1 suppressed FOXO1 expression as a novel therapeutic strategy for Ewing's sarcoma Cancer Research. 72: 2961-2961. DOI: 10.1158/1538-7445.Am2012-2961  0.386
2012 Schwentner R, Bilke S, Kauer M, Jug G, Walker RL, Meltzer PS, Kovar H. Abstract 2198: A functional ETS/E2F module in cancers expressing ETS fusion genes Cancer Research. 72: 2198-2198. DOI: 10.1158/1538-7445.Am2012-2198  0.38
2012 Zoppoli G, Solier S, Reinhold WC, Liu H, Connelly JW, Monks A, Shoemaker RH, Abaan OD, Davis SR, Piras D, Ballestrero A, Meltzer PS, Doroshow JH, Pommier Y. Abstract 2116:CHEK2(Chk2) endogenous activation is associated with p53 deficiency and downregulation ofBRCA2and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60) Cancer Research. 72: 2116-2116. DOI: 10.1158/1538-7445.Am2012-2116  0.417
2012 Abaan OD, Davis SR, Bilke S, Polley EC, Walker RL, Pineda M, Zhu YJ, Reinhold W, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. Abstract 1879: The exomes of the NCI60 and their implications for cancer pharmacogenomics Cancer Research. 72: 1879-1879. DOI: 10.1158/1538-7445.Am2012-1879  0.425
2012 Francis P, Moon SY, Bilke S, Zhu YJ, Walker RL, Pineda M, Li XL, Abaan O, Knight J, Davis S, Turner J, Wang H, Bruhn L, Lal A, Meltzer PS. Abstract 1113: Role of the microRNA-23∼27∼24 clusters in osteosarcoma Cancer Research. 72: 1113-1113. DOI: 10.1158/1538-7445.Am2012-1113  0.305
2011 Lee J, Petrini I, Hwang J, Giovannetti E, Voortman J, Wang Y, Steinberg SM, Funel N, Meltzer PS, Wang Y, Giaccone G. Array-based comparative genomic hybridization analysis to identify prognostic markers for resected pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 4097. PMID 28020443 DOI: 10.1200/Jco.2011.29.15_Suppl.4097  0.349
2011 Meltzer PS, Helman LJ. Genomic investigation of dedifferentiated liposarcoma suggests a role for therapeutic targeting of the tumor epigenome. Cancer Discovery. 1: 555-6. PMID 22586679 DOI: 10.1158/2159-8290.Cd-11-0291  0.324
2011 Qian Y, Hua E, Bisht K, Woditschka S, Skordos KW, Liewehr DJ, Steinberg SM, Brogi E, Akram MM, Killian JK, Edelman DC, Pineda M, Scurci S, Degenhardt YY, Laquerre S, ... ... Meltzer PS, et al. Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain. Clinical & Experimental Metastasis. 28: 899-908. PMID 21953073 DOI: 10.1007/S10585-011-9421-9  0.336
2011 Martin MM, Ryan M, Kim R, Zakas AL, Fu H, Lin CM, Reinhold WC, Davis SR, Bilke S, Liu H, Doroshow JH, Reimers MA, Valenzuela MS, Pommier Y, Meltzer PS, et al. Genome-wide depletion of replication initiation events in highly transcribed regions. Genome Research. 21: 1822-32. PMID 21813623 DOI: 10.1101/Gr.124644.111  0.304
2011 Killian JK, Bilke S, Davis S, Walker RL, Jaeger E, Killian MS, Waterfall JJ, Bibikova M, Fan JB, Smith WI, Meltzer PS. A methyl-deviator epigenotype of estrogen receptor-positive breast carcinoma is associated with malignant biology American Journal of Pathology. 179: 55-65. PMID 21641572 DOI: 10.1016/J.Ajpath.2011.03.022  0.351
2011 Valenzuela MS, Chen Y, Davis S, Yang F, Walker RL, Bilke S, Lueders J, Martin MM, Aladjem MI, Massion PP, Meltzer PS. Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences. Plos One. 6: e17308. PMID 21602917 DOI: 10.1371/Journal.Pone.0017308  0.351
2011 Rubin BP, Nishijo K, Chen HI, Yi X, Schuetze DP, Pal R, Prajapati SI, Abraham J, Arenkiel BR, Chen QR, Davis S, McCleish AT, Capecchi MR, Michalek JE, Zarzabal LA, ... ... Meltzer PS, et al. Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell. 19: 177-91. PMID 21316601 DOI: 10.1016/J.Ccr.2010.12.023  0.351
2011 Zaidi MR, Davis S, Noonan FP, Graff-Cherry C, Hawley TS, Walker RL, Feigenbaum L, Fuchs E, Lyakh L, Young HA, Hornyak TJ, Arnheiter H, Trinchieri G, Meltzer PS, De Fabo EC, et al. Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature. 469: 548-53. PMID 21248750 DOI: 10.1038/Nature09666  0.307
2011 Gough SM, Lee F, Chung YJ, Walker RL, Yang F, Zhu Y(, Ning Y, Meltzer PS, Aplan P. A NUP98-PHF23 Transgenic Mouse Model Develops AML and T-ALL Blood. 118: 2467-2467. DOI: 10.1182/Blood.V118.21.2467.2467  0.362
2011 Beachy SH, Onozawa M, Chung YJ, Slape C, Bilke S, Francis P, Pineda M, Walker RL, Meltzer PS, Aplan P. Enforced Expression of Lin28b Drives Development of Peripheral T Cell Lymphoma In Vivo Blood. 118: 1392-1392. DOI: 10.1182/Blood.V118.21.1392.1392  0.336
2011 Schwentner R, Kauer M, Bilke S, Jug G, Meltzer PS, Kovar H. Abstract 5341: Combinatorial regulation of E2F target genes by the oncogenic ETS transcription factor EWS-FLI1 Cancer Research. 71: 5341-5341. DOI: 10.1158/1538-7445.Am2011-5341  0.388
2011 Niedan S, Kauer M, Jug G, Walker RL, Meltzer PS, Kovar H. Abstract 5338: A repressive EWS-FLI1 subsignature is the result of FOXO1 suppression and nuclear exclusion Cancer Research. 71: 5338-5338. DOI: 10.1158/1538-7445.Am2011-5338  0.374
2011 Lu H, Si H, Yang X, Burnett J, Davis S, Sun H, Xiao W, Wei L, Meltzer P, Waes CV, Chen Z. Abstract 4968: TNF-alpha promotes genome-wide replacement of TAp73 chromatin occupancy by cREL and DeltaNp63 Cancer Research. 71: 4968-4968. DOI: 10.1158/1538-7445.Am2011-4968  0.348
2011 Abaan OD, Francis P, Pineda M, Walker R, Bilke S, Davis SR, Meltzer PS. Abstract 3934: Identification of novel cancer DNA sequence variants in human sarcomas Cancer Research. 71: 3934-3934. DOI: 10.1158/1538-7445.Am2011-3934  0.413
2011 Fitzgerald DP, Palmieri D, Qian Y, Deshpande M, Subramanian P, Graves C, Davis S, Meltzer P, Camphausen K, Becerra PS, Steeg PS. Abstract 2846: Pigment epithelium-derived factor (PEDF) functions as a brain metastasis suppressor of breast cancer Cancer Research. 71: 2846-2846. DOI: 10.1158/1538-7445.Am2011-2846  0.344
2010 Killian JK, Walker RL, Suuriniemi M, Jones L, Scurci S, Singh P, Cornelison R, Harmon S, Boisvert N, Zhu J, Wang Y, Bilke S, Davis S, Giaccone G, Smith WI, ... Meltzer PS, et al. Archival fine-needle aspiration cytopathology (FNAC) samples: untapped resource for clinical molecular profiling. The Journal of Molecular Diagnostics : Jmd. 12: 739-45. PMID 20959611 DOI: 10.2353/Jmoldx.2010.090238  0.338
2010 Cao L, Yu Y, Bilke S, Walker RL, Mayeenuddin LH, Azorsa DO, Yang F, Pineda M, Helman LJ, Meltzer PS. Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer. Cancer Research. 70: 6497-508. PMID 20663909 DOI: 10.1158/0008-5472.Can-10-0582  0.347
2010 Petrini I, Zucali PA, Lee HS, Pineda MA, Meltzer PS, Walter-Rodriguez B, Roncalli M, Santoro A, Wang Y, Giaccone G. Expression and mutational status of c-kit in thymic epithelial tumors. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 1447-53. PMID 20651610 DOI: 10.1097/Jto.0B013E3181E96E30  0.354
2010 Voortman J, Lee JH, Killian JK, Suuriniemi M, Wang Y, Lucchi M, Smith WI, Meltzer P, Giaccone G. Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors Proceedings of the National Academy of Sciences of the United States of America. 107: 13040-13045. PMID 20615970 DOI: 10.1073/Pnas.1008132107  0.4
2010 Aryee DN, Niedan S, Kauer M, Schwentner R, Bennani-Baiti IM, Ban J, Muehlbacher K, Kreppel M, Walker RL, Meltzer P, Poremba C, Kofler R, Kovar H. Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro. Cancer Research. 70: 4015-23. PMID 20442286 DOI: 10.1158/0008-5472.Can-09-4333  0.385
2010 Bolton KL, Garcia-Closas M, Pfeiffer RM, Duggan MA, Howat WJ, Hewitt SM, Yang XR, Cornelison R, Anzick SL, Meltzer P, Davis S, Lenz P, Figueroa JD, Pharoah PD, Sherman ME. Assessment of automated image analysis of breast cancer tissue microarrays for epidemiologic studies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 992-9. PMID 20332278 DOI: 10.1158/1055-9965.Epi-09-1023  0.666
2010 Anzick SL, Chen WD, Park Y, Meltzer P, Bell D, El-Naggar AK, Kaye FJ. Unfavorable prognosis of CRTC1-MAML2 positive mucoepidermoid tumors with CDKN2A deletions. Genes, Chromosomes & Cancer. 49: 59-69. PMID 19827123 DOI: 10.1002/Gcc.20719  0.673
2010 Schwentner R, Kauer MO, Bilke S, Jug G, Walker RL, Meltzer PS, Kovar H. Abstract 4968: Modes of co-factor recruitment by an oncogenic fusion protein Cancer Research. 70: 4968-4968. DOI: 10.1158/1538-7445.Am10-4968  0.374
2010 Yang F, Bilke S, Pineda M, Walker B, Zhu J, Meltzer P. Abstract 4612: Analysis of transcriptional regulation by progesterone receptor in ER-positive breast cancer cells by ChIP-Seq Cancer Research. 70: 4612-4612. DOI: 10.1158/1538-7445.Am10-4612  0.375
2010 Aryee DNT, Niedan S, Kauer M, Muehlbacher K, Walker RL, Meltzer P, Poremba C, Kofler R, Kovar H. Abstract 444: Hypoxia modulates EWS-FLI1 transcriptional signature and enhances invasiveness and anchorage-independent growth of Ewing's sarcoma cellsin-vitro Cancer Research. 70: 444-444. DOI: 10.1158/1538-7445.Am10-444  0.381
2010 Wentzensen NA, Killian K, Adams LG, Yang HP, Garcia-Closas M, Brinton LA, Lissowska J, Burke A, Hewitt S, Meltzer PS, Sherman ME. Abstract 2786: Methylation profiling of endometrial cancers from a population-based case control study Cancer Research. 70: 2786-2786. DOI: 10.1158/1538-7445.Am10-2786  0.382
2010 Gierach GL, Lissowska J, Garcia-Closas M, Yang XR, Figueroa JD, Anzick S, Wesolowska E, Brinton LA, Meltzer PS, Boyd NF, Sherman ME. Abstract 2779: Relationship of mammographic density with breast cancer subtypes Cancer Research. 70: 2779-2779. DOI: 10.1158/1538-7445.Am10-2779  0.679
2010 Abaan OD, Francis P, Pineda M, Walker RL, Bilke S, Davis SR, Meltzer PS. Abstract 2213: Identification of novel cancer mutations in sarcomas Cancer Research. 70: 2213-2213. DOI: 10.1158/1538-7445.Am10-2213  0.388
2010 Bilke S, Walker RL, Pineda M, Killian K, Abaan O, Meltzer PS. Abstract 2186: Error correcting DNA barcode allows for high throughput mutation screening in patient cohorts by multiplexed high throughput sequencing Cancer Research. 70: 2186-2186. DOI: 10.1158/1538-7445.Am10-2186  0.312
2010 Kauer MO, Jug G, Niedan S, Walker RL, Meltzer PS, Kovar H. Abstract 2009: A new repressive network module in Ewing's Sarcoma Cancer Research. 70: 2009-2009. DOI: 10.1158/1538-7445.Am10-2009  0.386
2010 Killian JK, Roth MJ, Singh PD, Walker R, Zhu J, Suuriniemi M, Chen Y, Wang G, Hu N, Taylor PR, Qiao Y, Dawsey SM, Meltzer PS. Abstract 1493: High-resolution comparative genomic hybridization of preneoplastic and invasive esophageal squamous cell carcinoma: Identification of the earliest preneoplastic changes Cancer Research. 70: 1493-1493. DOI: 10.1158/1538-7445.Am10-1493  0.388
2010 Suuriniemi M, Warren K, Killian K, Wang Y, Quezado M, Walker RL, Meltzer PS. Abstract 1148: Array comparative genomic hybridization of diffuse intrinsic pontine glioma samples obtained from formalin fixed paraffin embedded autopsy specimens Cancer Research. 70: 1148-1148. DOI: 10.1158/1538-7445.Am10-1148  0.388
2010 Meltzer P, Zaidi M, De Fabo E, Davis S, Hornyak T, Fuchs E, Arnheiter H, Trinchieri G, Noonan F, Merlino G. 28 Ultraviolet B-induced inflammatory microenvironment promotes melanocyte survival and melanoma susceptibility European Journal of Cancer Supplements. 8: 8. DOI: 10.1016/S1359-6349(10)70837-5  0.387
2009 Azad NS, Henning R, Yu M, Davidson B, Figg WD, Calvo K, Venkatasen A, Annunziata C, Meltzer P, Kohn E. Translational proof of mechanism (PoM) for sorafenib with bevacizumab: Endpoint analysis and clinical activity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 3574. PMID 27961719 DOI: 10.1200/Jco.2009.27.15_Suppl.3574  0.326
2009 Paoloni M, Davis S, Lana S, Withrow S, Sangiorgi L, Picci P, Hewitt S, Triche T, Meltzer P, Khanna C. Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression Bmc Genomics. 10: 625. PMID 20028558 DOI: 10.1186/1471-2164-10-625  0.37
2009 Palmieri D, Fitzgerald D, Shreeve SM, Hua E, Bronder JL, Weil RJ, Davis S, Stark AM, Merino MJ, Kurek R, Mehdorn HM, Davis G, Steinberg SM, Meltzer PS, Aldape K, et al. Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. Molecular Cancer Research : McR. 7: 1438-45. PMID 19723875 DOI: 10.1158/1541-7786.Mcr-09-0234  0.374
2009 Kauer M, Ban J, Kofler R, Walker B, Davis S, Meltzer P, Kovar H. A molecular function map of Ewing's sarcoma. Plos One. 4: e5415. PMID 19404404 DOI: 10.1371/Journal.Pone.0005415  0.41
2009 Kralj JG, Player A, Sedrick H, Munson MS, Petersen D, Forry SP, Meltzer P, Kawasaki E, Locascio LE. T7-based linear amplification of low concentration mRNA samples using beads and microfluidics for global gene expression measurements. Lab On a Chip. 9: 917-24. PMID 19294302 DOI: 10.1039/B811714D  0.346
2009 Killian JK, Bilke S, Davis S, Walker RL, Killian MS, Jaeger EB, Chen Y, Hipp J, Pittaluga S, Raffeld M, Cornelison R, Smith WI, Bibikova M, Fan JB, Emmert-Buck MR, ... ... Meltzer PS, et al. Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome. Cancer Research. 69: 758-64. PMID 19155300 DOI: 10.1158/0008-5472.Can-08-2984  0.355
2009 Gartside MG, Chen H, Ibrahimi OA, Byron SA, Curtis AV, Wellens CL, Bengston A, Yudt LM, Eliseenkova AV, Ma J, Curtin JA, Hyder P, Harper UL, Riedesel E, Mann GJ, ... ... Meltzer PS, et al. Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Molecular Cancer Research : McR. 7: 41-54. PMID 19147536 DOI: 10.1158/1541-7786.Mcr-08-0021  0.324
2009 John S, Johnson TA, Sung MH, Biddie SC, Trump S, Koch-Paiz CA, Davis SR, Walker R, Meltzer PS, Hager GL. Kinetic complexity of the global response to glucocorticoid receptor action. Endocrinology. 150: 1766-74. PMID 19131569 DOI: 10.1210/En.2008-0863  0.317
2009 Rahman M, Davis SR, Pumphrey JG, Bao J, Nau MM, Meltzer PS, Lipkowitz S. TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype. Breast Cancer Research and Treatment. 113: 217-30. PMID 18266105 DOI: 10.1007/S10549-008-9924-5  0.343
2009 Suuriniemi M, Killian K, Walker R, Edelman D, Meltzer P. Abstract B179: An improved method for array comparative genomic hybridization of formalin fixed paraffin embedded surgical pathology specimens Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B179  0.315
2009 Roessler S, Long L, Budhu A, Chen Y, Zhao X, Walker R, Jia H, Ye Q, Qin L, Tang Z, Hunter K, Thorgeirsson S, Meltzer P, Wang X. Abstract A25: Array‐based comparative genomic hybridization of hepatocellular carcinoma reveals a unique genomic aberration pattern in tumors with poor prognosis Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A25  0.357
2008 Shreeve SM, Palmieri D, Johnson MM, Aldape KD, Davis S, Meltzer PS, Davis GL, Hoffmann CM, Steinberg SM, Steeg PS. Correlation of hexokinase-2 expression with overall survival and potential as a therapeutic target in the treatment of breast cancer brain metastases. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 1005. PMID 27951392 DOI: 10.1200/Jco.2008.26.15_Suppl.1005  0.343
2008 Balleine RL, Webster LR, Davis S, Salisbury EL, Palazzo JP, Schwartz GF, Cornfield DB, Walker RL, Byth K, Clarke CL, Meltzer PS. Molecular grading of ductal carcinoma in situ of the breast. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 8244-52. PMID 19088042 DOI: 10.1158/1078-0432.Ccr-08-0939  0.348
2008 Park Y, Kubo A, Komiya T, Coxon A, Beebe K, Neckers L, Meltzer PS, Kaye FJ. Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras. Cell Cycle (Georgetown, Tex.). 7: 2384-91. PMID 18677112 DOI: 10.4161/Cc.6363  0.359
2008 Chen HI, Hsu FH, Jiang Y, Tsai MH, Yang PC, Meltzer PS, Chuang EY, Chen Y. A probe-density-based analysis method for array CGH data: simulation, normalization and centralization. Bioinformatics (Oxford, England). 24: 1749-56. PMID 18603568 DOI: 10.1093/Bioinformatics/Btn321  0.376
2008 Farrar JE, Nater M, Caywood E, McDevitt MA, Kowalski J, Takemoto CM, Talbot CC, Meltzer P, Esposito D, Beggs AH, Schneider HE, Grabowska A, Ball SE, Niewiadomska E, Sieff CA, et al. Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia. Blood. 112: 1582-92. PMID 18535205 DOI: 10.1182/Blood-2008-02-140012  0.397
2008 Boyle AP, Davis S, Shulha HP, Meltzer P, Margulies EH, Weng Z, Furey TS, Crawford GE. High-resolution mapping and characterization of open chromatin across the genome. Cell. 132: 311-22. PMID 18243105 DOI: 10.1016/J.Cell.2007.12.014  0.339
2008 Amundson SA, Do KT, Vinikoor LC, Lee RA, Koch-Paiz CA, Ahn J, Reimers M, Chen Y, Scudiero DA, Weinstein JN, Trent JM, Bittner ML, Meltzer PS, Fornace AJ. Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen. Cancer Research. 68: 415-24. PMID 18199535 DOI: 10.1158/0008-5472.Can-07-2120  0.388
2007 Kamradt J, Jung V, Wahrheit K, Tolosi L, Rahnenfuehrer J, Schilling M, Walker R, Davis S, Stoeckle M, Meltzer P, Wullich B. Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH Plos One. 2: 1-7. PMID 17712417 DOI: 10.1371/Journal.Pone.0000769  0.35
2007 Kim KT, Baird K, Davis S, Piloto O, Levis M, Li L, Chen P, Meltzer P, Small D. Constitutive Fms-like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells. British Journal of Haematology. 138: 603-15. PMID 17686054 DOI: 10.1111/J.1365-2141.2007.06696.X  0.349
2007 Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS. Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. Cancer Research. 67: 7238-46. PMID 17671192 DOI: 10.1158/0008-5472.Can-07-0962  0.372
2007 Quignodon L, Grijota-Martinez C, Compe E, Guyot R, Allioli N, Laperrière D, Walker R, Meltzer P, Mader S, Samarut J, Flamant F. A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum. Journal of Molecular Endocrinology. 39: 17-28. PMID 17601882 DOI: 10.1677/Jme-06-0054  0.353
2007 Davis S, Meltzer PS. GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor. Bioinformatics (Oxford, England). 23: 1846-7. PMID 17496320 DOI: 10.1093/Bioinformatics/Btm254  0.306
2007 Davis SR, Meltzer PS. Modeling synovial sarcoma: timing is everything. Cancer Cell. 11: 305-7. PMID 17418406 DOI: 10.1016/J.Ccr.2007.03.016  0.368
2007 Bruce B, Khanna G, Ren L, Landberg G, Jirström K, Powell C, Borczuk A, Keller ET, Wojno KJ, Meltzer P, Baird K, McClatchey A, Bretscher A, Hewitt SM, Khanna C. Expression of the cytoskeleton linker protein ezrin in human cancers. Clinical & Experimental Metastasis. 24: 69-78. PMID 17370041 DOI: 10.1007/S10585-006-9050-X  0.366
2007 Leotlela PD, Wade MS, Duray PH, Rhode MJ, Brown HF, Rosenthal DT, Dissanayake SK, Earley R, Indig FE, Nickoloff BJ, Taub DD, Kallioniemi OP, Meltzer P, Morin PJ, Weeraratna AT. Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility Oncogene. 26: 3846-3856. PMID 17160014 DOI: 10.1038/Sj.Onc.1210155  0.33
2007 Johnston JJ, Walker RL, Davis S, Facio F, Turner JT, Bick DP, Daentl DL, Ellison JW, Meltzer PS, Biesecker LG. Zoom-in comparative genomic hybridisation arrays for the characterisation of variable breakpoint contiguous gene syndromes. Journal of Medical Genetics. 44: e59. PMID 17098889 DOI: 10.1136/Jmg.2006.042473  0.355
2007 Farrar J, Nater M, Caywood E, McDevitt M, Kowalski J, Takemoto C, Talbot C, Meltzer P, Esposito D, Beggs A, Schneider H, Grabowska A, Ball S, Niewiadomska E, Sieff C, et al. A Large Ribosomal Subunit Protein Abnormality in Diamond-Blackfan Anemia (DBA). Blood. 110: 422-422. DOI: 10.1182/Blood.V110.11.422.422  0.411
2006 Bruijn DRHd, Allander SV, Dijk AHAv, Willemse MP, Thijssen J, Groningen JJMv, Meltzer PS, Kessel AGv. The Synovial Sarcoma–Associated SS18-SSX2 Fusion Protein Induces Epigenetic Gene (De)Regulation Cancer Research. 66: 9474-9482. PMID 17018603 DOI: 10.1158/0008-5472.Can-05-3726  0.371
2006 Crawford GE, Davis S, Scacheri PC, Renaud G, Halawi MJ, Erdos MR, Green R, Meltzer PS, Wolfsberg TG, Collins FS. DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays. Nature Methods. 3: 503-9. PMID 16791207 DOI: 10.1038/Nmeth888  0.333
2006 Davis S, Meltzer PS. Ewing's sarcoma: General insights from a rare model Cancer Cell. 9: 331-332. PMID 16697953 DOI: 10.1016/J.Ccr.2006.05.003  0.33
2006 Li HM, Man C, Jin Y, Deng W, Yip YL, Feng HC, Cheung YC, Lo KW, Meltzer PS, Wu ZG, Kwong YL, Yuen AP, Tsao SW. Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase. International Journal of Cancer. Journal International Du Cancer. 119: 1567-76. PMID 16688717 DOI: 10.1002/Ijc.22032  0.371
2006 Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS. Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. Plos Genetics. 2: e51. PMID 16604156 DOI: 10.1371/Journal.Pgen.0020051  0.4
2006 Seftor EA, Meltzer PS, Kirschmann DA, Margaryan NV, Seftor RE, Hendrix MJ. The epigenetic reprogramming of poorly aggressive melanoma cells by a metastatic microenvironment. Journal of Cellular and Molecular Medicine. 10: 174-96. PMID 16563230 DOI: 10.1111/J.1582-4934.2006.Tb00299.X  0.371
2006 Gantt NM, Walker B, Lee YT, Jiang Y, Staker P, Oneal PA, Bhanu NV, Meltzer PS, Miller JL. Genomic Composition of Howell-Jolly Bodies. Blood. 108: 1570-1570. DOI: 10.1182/Blood.V108.11.1570.1570  0.327
2005 Baird K, Davis S, Antonescu CR, Harper UL, Walker RL, Chen Y, Glatfelter AA, Duray PH, Meltzer PS. Gene expression profiling of human sarcomas: Insights into sarcoma biology Cancer Research. 65: 9226-9235. PMID 16230383 DOI: 10.1158/0008-5472.Can-05-1699  0.394
2005 Meltzer PS. Cancer genomics: Small RNAs with big impacts Nature. 435: 745-746. PMID 15944682 DOI: 10.1038/435745A  0.344
2005 Moeller LC, Dumitrescu AM, Walker RL, Meltzer PS, Refetoff S. Thyroid hormone responsive genes in cultured human fibroblasts. The Journal of Clinical Endocrinology and Metabolism. 90: 936-43. PMID 15507505 DOI: 10.1210/Jc.2004-1768  0.362
2005 Kim KT, Baird K, Ahn JY, Meltzer P, Lilly M, Levis M, Small D. Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival. Blood. 105: 1759-67. PMID 15498859 DOI: 10.1182/Blood-2004-05-2006  0.333
2005 Barrett M, Sampas N, Ben-Dor A, Scheffer A, Anderson P, Tsang P, Gooden C, Walker R, Curry B, Kincaid R, Lipson D, Bittner M, Yakhini Z, Meltzer P, Bruhn L, et al. Comparative genomic hybridization using oligonucleotide arrays and total genomic DNA Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1170  0.362
2004 Meltzer PS. Gene Expression Profiling in Breast Cancer Research Breast Disease. 19: 23-27. PMID 15687694 DOI: 10.3233/Bd-2004-19104  0.404
2004 Barrett MT, Scheffer A, Ben-Dor A, Sampas N, Lipson D, Kincaid R, Tsang P, Curry B, Baird K, Meltzer PS, Yakhini Z, Bruhn L, Laderman S. Comparative genomic hybridization using oligonucleotide microarrays and total genomic DNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 17765-70. PMID 15591353 DOI: 10.1073/Pnas.0407979101  0.364
2004 Wang Q, Anzick S, Richter WF, Meltzer P, Simons SS. Modulation of transcriptional sensitivity of mineralocorticoid and estrogen receptors Journal of Steroid Biochemistry and Molecular Biology. 91: 197-210. PMID 15336697 DOI: 10.1016/J.Jsbmb.2004.04.007  0.639
2004 Sood R, Bader PI, Speer MC, Edwards YH, Eddings EM, Blair RT, Hu P, Faruque MU, Robbins CM, Zhang H, Leuders J, Morrison K, Thompson D, Schwartzberg PL, Meltzer PS, et al. Cloning and characterization of an inversion breakpoint at 6q23.3 suggests a role for Map7 in sacral dysgenesis. Cytogenetic and Genome Research. 106: 61-7. PMID 15218243 DOI: 10.1159/000078563  0.35
2004 Håkansson P, Segal D, Lassen C, Gullberg U, Morse HC, Fioretos T, Meltzer PS. Identification of genes differentially regulated by the P210 BCR/ABL1 fusion oncogene using cDNA microarrays. Experimental Hematology. 32: 476-482. PMID 15145216 DOI: 10.1016/J.Exphem.2004.02.012  0.383
2004 Koch-Paiz CA, Amundson SA, Bittner ML, Meltzer PS, Fornace AJ. Functional genomics of UV radiation responses in human cells. Mutation Research. 549: 65-78. PMID 15120963 DOI: 10.1016/J.Mrfmmm.2004.01.010  0.318
2004 Pavey S, Johansson P, Packer L, Taylor J, Stark M, Pollock PM, Walker GJ, Boyle GM, Harper U, Cozzi SJ, Hansen K, Yudt L, Schmidt C, Hersey P, Ellem KA, ... ... Meltzer P, et al. Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene. 23: 4060-7. PMID 15048078 DOI: 10.1038/Sj.Onc.1207563  0.33
2004 Guo Z, Linn JF, Wu G, Anzick SL, Eisenberger CF, Halachmi S, Cohen Y, Fomenkov A, Hoque MO, Okami K, Steiner G, Engles JM, Osada M, Moon C, Ratovitski E, ... ... Meltzer PS, et al. CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer. Nature Medicine. 10: 374-81. PMID 15034568 DOI: 10.1038/Nm1010  0.714
2004 Weeraratna AT, Becker D, Carr KM, Duray PH, Rosenblatt KP, Yang S, Chen Y, Bittner M, Strausberg RL, Riggins GJ, Wagner U, Kallioniemi OP, Trent JM, Morin PJ, Meltzer PS. Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome. Oncogene. 23: 2264-74. PMID 14755246 DOI: 10.1038/Sj.Onc.1207337  0.374
2004 Smith AP, Weeraratna AT, Spears JR, Meltzer PS, Becker D. SAGE identification and fluorescence imaging analysis of genes and transcripts in melanomas and precursor lesions. Cancer Biology & Therapy. 3: 104-9. PMID 14726694 DOI: 10.4161/Cbt.3.1.661  0.334
2004 Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, Merlino G. Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nature Medicine. 10: 175-81. PMID 14704789 DOI: 10.1038/Nm966  0.381
2004 Kim K, Baird K, Davis S, Levis M, Piloto O, Li L, Chen P, Meltzer P, Small D. Constitutive FLT3 Activation Results in Specific Changes in Gene Expression in Myeloid Leukemic Cells. Blood. 104: 1115-1115. DOI: 10.1182/Blood.V104.11.1115.1115  0.39
2004 Guo Z, Linn JF, Wu G, Anzick SL, Eisenberger CF, Halachmi S, Cohen Y, Fomenkov A, Hoque MO, Okami K, Steiner G, Engles JM, Osada M, Moon C, Ratovitski E, ... ... Meltzer PS, et al. Erratum: Corrigendum: CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer Nature Medicine. 10: 1139-1139. DOI: 10.1038/Nm1004-1139B  0.678
2003 Anzick SL, Azorsa DO, Simons SS, Meltzer PS. Phenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1 Bmc Cancer. 3. PMID 12964942 DOI: 10.1186/1471-2407-3-22  0.697
2003 Bomprezzi R, Ringnér M, Kim S, Bittner ML, Khan J, Chen Y, Elkahloun A, Yu A, Bielekova B, Meltzer PS, Martin R, McFarland HF, Trent JM. Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease. Human Molecular Genetics. 12: 2191-9. PMID 12915464 DOI: 10.1093/Hmg/Ddg221  0.327
2003 Ying H, Suzuki H, Furumoto H, Walker R, Meltzer P, Willingham MC, Cheng S. Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma. Carcinogenesis. 24: 1467-1479. PMID 12869418 DOI: 10.1093/Carcin/Bgg111  0.428
2003 Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, Meltzer PS. Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. Embo Reports. 4: 581-7. PMID 12776178 DOI: 10.1038/Sj.Embor.Embor862  0.328
2003 Pollock PM, Cohen-Solal K, Sood R, Namkoong J, Martino JJ, Koganti A, Zhu H, Robbins C, Makalowska I, Shin SS, Marin Y, Roberts KG, Yudt LM, Chen A, Cheng J, ... ... Meltzer PS, et al. Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia. Nature Genetics. 34: 108-12. PMID 12704387 DOI: 10.1038/Ng1148  0.349
2003 Hedenfalk I, Ringner M, Ben-Dor A, Yakhini Z, Chen Y, Chebil G, Ach R, Loman N, Olsson H, Meltzer P, Borg A, Trent J. Molecular classification of familial non-BRCA1/BRCA2 breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 100: 2532-7. PMID 12610208 DOI: 10.1073/Pnas.0533805100  0.378
2003 Gruvberger SK, Ringnér M, Edén P, Borg A, Fernö M, Peterson C, Meltzer PS. Expression profiling to predict outcome in breast cancer: the influence of sample selection. Breast Cancer Research : Bcr. 5: 23-6. PMID 12559041 DOI: 10.1186/Bcr548  0.357
2003 Seftor REB, Seftor EA, Hess AR, Meltzer PS, Hendrix MJC. The role of the vasculogenic phenotype and its associated extracellular matrix in tumor progression Implications for immune surveillance Clinical and Applied Immunology Reviews. 3: 263-276. DOI: 10.1016/S1529-1049(02)00123-X  0.354
2002 Allander SV, Illei PB, Chen Y, Antonescu CR, Bittner M, Ladanyi M, Meltzer PS. Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation. The American Journal of Pathology. 161: 1587-95. PMID 12414507 DOI: 10.1016/S0002-9440(10)64437-9  0.301
2002 Seftor EA, Meltzer PS, Schatteman GC, Gruman LM, Hess AR, Kirschmann DA, Seftor RE, Hendrix MJ. Expression of multiple molecular phenotypes by aggressive melanoma tumor cells: role in vasculogenic mimicry. Critical Reviews in Oncology/Hematology. 44: 17-27. PMID 12398997 DOI: 10.1016/S1040-8428(01)00199-8  0.36
2002 Mackall CL, Meltzer PS, Helman LJ. Focus on sarcomas. Cancer Cell. 2: 175-178. PMID 12242149 DOI: 10.1016/S1535-6108(02)00132-0  0.349
2002 Lumkul R, Gorin NC, Malehorn MT, Hoehn GT, Zheng R, Baldwin B, Small D, Gore S, Smith D, Meltzer PS, Civin CI. Human AML cells in NOD/SCID mice: engraftment potential and gene expression. Leukemia. 16: 1818-26. PMID 12200698 DOI: 10.1038/Sj.Leu.2402632  0.32
2002 Pollock PM, Meltzer PS. A genome-based strategy uncovers frequent BRAF mutations in melanoma. Cancer Cell. 2: 5-7. PMID 12150818 DOI: 10.1016/S1535-6108(02)00089-2  0.325
2002 Pollock PM, Meltzer PS. Lucky draw in the gene raffle. Nature. 417: 906-7. PMID 12087387 DOI: 10.1038/417906A  0.379
2002 Seftor EA, Meltzer PS, Kirschmann DA, Pe'er J, Maniotis AJ, Trent JM, Folberg R, Hendrix MJ. Molecular determinants of human uveal melanoma invasion and metastasis. Clinical & Experimental Metastasis. 19: 233-46. PMID 12067204 DOI: 10.1023/A:1015591624171  0.41
2002 Khan J, Saal LH, Bittner ML, Jiang Y, Gooden GC, Glatfelter AA, Meltzer PS. Gene expression profiling in cancer using cDNA microarrays. Methods in Molecular Medicine. 68: 205-222. PMID 11901504 DOI: 10.1385/1-59259-135-3:205  0.383
2002 Shaheduzzaman S, Krishnan V, Petrovic A, Bittner M, Meltzer P, Trent J, Venkatesan S, Zeichner S. Effects of HIV-1 Nef on cellular gene expression profiles. Journal of Biomedical Science. 9: 82-96. PMID 11810028 DOI: 10.1007/Bf02256581  0.371
2002 Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, ... ... Meltzer P, et al. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nature Genetics. 30: 181-4. PMID 11799394 DOI: 10.1038/Ng823  0.35
2001 Azorsa DO, Cunliffe HE, Meltzer PS. Association of steroid receptor coactivator AIB1 with estrogen receptor-alpha in breast cancer cells. Breast Cancer Research and Treatment. 70: 89-101. PMID 11768608 DOI: 10.1023/A:1012972808558  0.337
2001 Wiltshire RN, Dennis TR, Sondak VK, Meltzer PS, Trent JM. Application of molecular cytogenetic techniques in a case study of human cutaneous metastatic melanoma. Cancer Genetics and Cytogenetics. 131: 97-103. PMID 11750048 DOI: 10.1016/S0165-4608(01)00539-8  0.345
2001 Hoffmann KF, McCarty TC, Segal DH, Chiaramonte M, Hesse M, Davis EM, Cheever AW, Meltzer PS, Morse HC, Wynn TA. Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2545-7. PMID 11641263 DOI: 10.1096/Fj.01-0306Fje  0.324
2001 Ng PW, Iha H, Iwanaga Y, Bittner M, Chen Y, Jiang Y, Gooden G, Trent JM, Meltzer P, Jeang KT, Zeichner SL. Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation. Oncogene. 20: 4484-96. PMID 11494144 DOI: 10.1038/Sj.Onc.1204513  0.373
2001 Amundson SA, Bittner M, Meltzer P, Trent J, Fornace AJ. Physiological function as regulation of large transcriptional programs: the cellular response to genotoxic stress. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 129: 703-10. PMID 11435125 DOI: 10.1016/S1096-4959(01)00389-X  0.374
2001 Hendrix MJC, Seftor EA, Meltzer PS, Gardner LMG, Hess AR, Kirschmann DA, Schatteman GC, Seftor REB. Expression and functional significance of VE-cadherin in aggressive human melanoma cells: Role in vasculogenic mimicry Proceedings of the National Academy of Sciences of the United States of America. 98: 8018-8023. PMID 11416160 DOI: 10.1073/Pnas.131209798  0.344
2001 Khan J, Wei JS, Ringnér M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C, Meltzer PS. Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks Nature Medicine. 7: 673-679. PMID 11385503 DOI: 10.1038/89044  0.365
2001 Meltzer PS. Spotting the target: microarrays for disease gene discovery. Current Opinion in Genetics & Development. 11: 258-263. PMID 11377960 DOI: 10.1016/S0959-437X(00)00187-8  0.348
2001 Feng X, Jiang Y, Meltzer P, Yen PM. Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation. Journal of Biological Chemistry. 276: 15066-15072. PMID 11328825 DOI: 10.1074/Jbc.M011027200  0.321
2001 Paulose-Murphy M, Ha NK, Xiang C, Chen Y, Gillim L, Yarchoan R, Meltzer P, Bittner M, Trent J, Zeichner S. Transcription program of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) Journal of Virology. 75: 4843-4853. PMID 11312356 DOI: 10.1128/Jvi.75.10.4843-4853.2001  0.316
2001 Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi OP, Wilfond B, Borg A, Trent J, Raffeld M, Yakhini Z, et al. Gene-expression profiles in hereditary breast cancer. The New England Journal of Medicine. 344: 539-48. PMID 11207349 DOI: 10.1056/Nejm200102223440801  0.396
2001 Karhu R, Ahlstedt-Soini M, Bittner M, Meltzer P, Trent JM, Isola JJ. Chromosome arm-specific multicolor FISH Genes Chromosomes and Cancer. 30: 105-109. PMID 11107184 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1068>3.0.Co;2-9  0.302
2001 Forus A, Khan J, Myklebost O, Meltzer PS. Microarray-based analysis of gene activity patterns in osteosarcoma Nature Genetics. 27: 75-75. DOI: 10.1038/87224  0.307
2001 Merajver S, Wu Z, Chang T, Mirshahidi H, Meltzer P, vanGolen K. Microarray analysis of RhoC-transformed mammary epithelial cells suggests molecular mechanisms of inflammatory breast cancer Nature Genetics. 27: 73-73. DOI: 10.1038/87212  0.318
2001 Khan J, Wei J, Saal L, Marc L, Markus R, Peterson C, Chen Y, Meltzer P. Development of a molecular taxonomy of small blue round-cell tumors using cDNA microarrays Nature Genetics. 27: 64-64. DOI: 10.1038/87150  0.318
2001 Chen Y, Zhang H, Panavally S, Dougherty E, Bittner M, Meltzer P, Trent J. cDNA microarray analysis using both gene expression ratios and intensities Nature Genetics. 27: 46-47. DOI: 10.1038/87032  0.331
2001 Carr K, Bittner M, Chen Y, Meltzer P, Duray P, Sondak V, Trent J. Relationship between gene expression profile and clinical outcome in malignant melanoma Nature Genetics. 27: 46-46. DOI: 10.1038/87026  0.309
2001 Adya N, Chen Y, Hilgenfeld E, Khan J, Bittner M, Serve H, Berdel WE, Meltzer P, Liu PP. Characterizing gene expression profile of Inv(16)-associated leukemia Nature Genetics. 27: 37-37. DOI: 10.1038/86966  0.348
2000 Patel MS, Cole DE, Smith JD, Hawker GA, Wong B, Trang H, Vieth R, Meltzer P, Rubin LA. Alleles of the estrogen receptor alpha-gene and an estrogen receptor cotranscriptional activator gene, amplified in breast cancer-1 (AIB1), are associated with quantitative calcaneal ultrasound. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 2231-9. PMID 11092404 DOI: 10.1359/Jbmr.2000.15.11.2231  0.333
2000 Tikkanen MK, Carter DJ, Harris AM, Le HM, Azorsa DO, Meltzer PS, Murdoch FE. Endogenously expressed estrogen receptor and coactivator AIB1 interact in MCF-7 human breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 12536-40. PMID 11050174 DOI: 10.1073/Pnas.220427297  0.356
2000 Amundson SA, Do KT, Shahab S, Bittner M, Meltzer P, Trent J, Fornace AJ. Identification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation. Radiation Research. 154: 342-6. PMID 11012342 DOI: 10.1667/0033-7587(2000)154[0342:Iopmbi]2.0.Co;2  0.304
2000 Kim S, Dougherty ER, Chen Y, Sivakumar K, Meltzer P, Trent JM, Bittner M. Multivariate measurement of gene expression relationships. Genomics. 67: 201-9. PMID 10903845 DOI: 10.1006/Geno.2000.6241  0.372
2000 Feng X, Jiang Y, Meltzer P, Yen PM. Thyroid Hormone Regulation of Hepatic Genes in Vivo Detected by Complementary DNA Microarray Molecular Endocrinology. 14: 947-955. PMID 10894146 DOI: 10.1210/Mend.14.7.0470  0.329
2000 Oda T, Elkahloun AG, Meltzer PS, Okajima K, Sugiyama K, Wada Y, Chandrasekharappa SC. Identification of a larger than 3 Mb deletion including JAG1 in an Alagille syndrome patient with a translocation t(3;20)(q13.3;p12.2). Human Mutation. 16: 92. PMID 10874319 DOI: 10.1002/1098-1004(200007)16:1<92::Aid-Humu23>3.0.Co;2-4  0.322
2000 Wiegant J, Bezrookove V, Rosenberg C, Tanke HJ, Raap AK, Zhang H, Bittner M, Trent JM, Meltzer P. Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization. Genome Research. 10: 861-5. PMID 10854417 DOI: 10.1101/Gr.10.6.861  0.313
2000 Lee SK, Na SY, Jung SY, Choi JE, Jhun BH, Cheong J, Meltzer PS, Lee YC, Lee JW. Activating protein-1, nuclear factor-κB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2 Molecular Endocrinology. 14: 915-925. PMID 10847592 DOI: 10.1210/Mend.14.6.0471  0.309
2000 Stephan DA, Chen Y, Jiang Y, Malechek L, Gu JZ, Robbins CM, Bittner ML, Morris JA, Carstea E, Meltzer PS, Adler K, Garlick R, Trent JM, Ashlock MA. Positional cloning utilizing genomic DNA microarrays: the Niemann-Pick type C gene as a model system. Molecular Genetics and Metabolism. 70: 10-8. PMID 10833327 DOI: 10.1006/Mgme.2000.2989  0.384
2000 Matsuo T, Stauffer JK, Walker RL, Meltzer P, Thiele CJ. Structure and Promoter Analysis of the Humanunc-33-like Phosphoprotein Gene E-BOX REQUIRED FOR MAXIMAL EXPRESSION IN NEUROBLASTOMA AND MYOBLASTS Journal of Biological Chemistry. 275: 16560-16568. PMID 10748015 DOI: 10.1074/Jbc.M001312200  0.394
2000 Zhang J, Zhang LX, Meltzer PS, Barrett JC, Trent JM. Molecular cloning of human hic‐5, a potential regulator involved in signal transduction and cellular senescence Molecular Carcinogenesis. 27: 177-183. PMID 10708479 DOI: 10.1002/(Sici)1098-2744(200003)27:3<177::Aid-Mc4>3.0.Co;2-S  0.37
2000 O'Hagan RC, Schreiber-Agus N, Chen K, David G, Engelman JA, Schwab R, Alland L, Thomson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nature Genetics. 24: 113-9. PMID 10655054 DOI: 10.1038/72761  0.364
1999 Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW. A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo Journal of Biological Chemistry. 274: 34283-34293. PMID 10567404 DOI: 10.1074/Jbc.274.48.34283  0.664
1999 Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene Proceedings of the National Academy of Sciences of the United States of America. 96: 13264-13269. PMID 10557309 DOI: 10.1073/Pnas.96.23.13264  0.369
1999 Azorsa DO, Meltzer PS. Production and characterization of monoclonal antibodies to the steroid receptor coactivator AIB1. Hybridoma. 18: 281-287. PMID 10475243 DOI: 10.1089/027245799315943  0.333
1999 Loftus SK, Chen Y, Gooden G, Ryan JF, Birznieks G, Hilliard M, Baxevanis AD, Bittner M, Meltzer P, Trent J, Pavan W. Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis. Proceedings of the National Academy of Sciences of the United States of America. 96: 9277-80. PMID 10430933 DOI: 10.1038/14355  0.356
1999 Amundson SA, Bittner M, Chen Y, Trent J, Meltzer P, Fornace AJ. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses Oncogene. 18: 3666-3672. PMID 10380890 DOI: 10.1038/Sj.Onc.1202676  0.379
1999 Khan J, Saal LH, Bittner ML, Chen Y, Trent JM, Meltzer PS. Expression profiling in cancer using cDNA microarrays Electrophoresis. 20: 223-229. PMID 10197427 DOI: 10.1002/(Sici)1522-2683(19990201)20:2<223::Aid-Elps223>3.0.Co;2-A  0.38
1999 Kumar S, Pack S, Kumar D, Walker R, Quezado M, Zhuang Z, Meltzer P, Tsokos M. Detection of EWS-FLI-1 fusion in Ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffin-embedded tissue. Human Pathology. 30: 324-330. PMID 10088552 DOI: 10.1016/S0046-8177(99)90012-6  0.344
1999 Ghadimi BM, Schröck E, Walker RL, Wangsa D, Jauho A, Meltzer PS, Ried T. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas American Journal of Pathology. 154: 525-536. PMID 10027410 DOI: 10.1016/S0002-9440(10)65298-4  0.359
1999 Duggan DJ, Bittner M, Chen Y, Meltzer P, Trent JM. Expression profiling using cDNA microarrays Nature Genetics. 21: 10-14. PMID 9915494 DOI: 10.1038/4434  0.336
1999 Teichmann U, Schuler G, Moore T, Otsuka T, Merlino G, Khan J, Chen Y, Bittner M, Meltzer P, Trent J, Pavan W. Development of a mouse-specific cDNA set for microarray gene expression analysis: differential gene expression in melanocyte lineage samples of the neural crest Nature Genetics. 23: 78-78. DOI: 10.1038/14414  0.341
1999 O'Hagan R, Schreiber-Agus N, Engelman JA, Schwab R, Alland L, Thompson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Identification of differentially regulated gene targets in the Myc and Mad family proteins Nature Genetics. 23: 66-66. DOI: 10.1038/14378  0.304
1999 Meltzer PS, Maniotis AJ, Folberg R, Hess A, Seftor EA, Gardner LMG, Pe'er J, Trent JM, Hendrix MJC. An altered gene expression profile is associated with tumour vasculogenesis by human melanoma cells Nature Genetics. 23: 62-62. DOI: 10.1038/14364  0.353
1999 Li H, Chen Y, Jiang Y, Bittner ML, Meltzer PS, Trent JM, Yamada KM, Yamada Y. Profiling expression patterns of 2,214 unigenes in mouse craniofacial development by cDNA microarray analysis Nature Genetics. 23: 57-58. DOI: 10.1038/14349  0.364
1999 Jiang Y, Chen Y, Su Y, Wang E, Marincola FM, Dougherty ER, Meltzer PS, Bittner M, Trent JM. Evaluating altered levels of gene expression in cancer cells Nature Genetics. 23: 54-54. DOI: 10.1038/14335  0.386
1999 Fornace AJ, Amundson SA, Bittner M, Weinstein J, Meltzer P, Trent J, Myers TG. Stress gene expression: analysis by informatics and functional genomics approaches Nature Genetics. 23: 45-45. DOI: 10.1038/14305  0.316
1999 Dougherty ER, Kim S, Bittner ML, Chen Y, Sivakumar K, Meltzer P, Trent JM. Nonlinear stochastic determination for gene expressions via cDNA microarrays Nature Genetics. 23: 41-41. DOI: 10.1038/14294  0.307
1999 Chin K, Kudoh K, Ramanna M, Elkahloun AG, Bittner ML, Meltzer PS, Trent JM, Dalton WS. Analysis of the mechanisms of drug resistance in cancer by cDNA microarray Nature Genetics. 23: 38-38. DOI: 10.1038/14284  0.351
1998 Guan XY, Zhang H, Yang JM, Wang J, Taetle R, Meltzer PS, Trent JM. Detection of chromosome 6 abnormalities in melanoma cell lines by chromosome arm painting probes Cancer Genetics and Cytogenetics. 107: 89-92. PMID 9844599 DOI: 10.1016/S0165-4608(98)00080-6  0.31
1998 Ermolaeva O, Rastogi M, Pruitt KD, Schuler GD, Bittner ML, Chen Y, Simon R, Meltzer P, Trent JM, Boguski MS. Data management and analysis for gene expression arrays. Nature Genetics. 20: 19-23. PMID 9731524 DOI: 10.1038/1670  0.331
1998 Teichmann U, Ray ME, Ellison J, Graham C, Wistow G, Meltzer PS, Trent JM, Pavan WJ. Cloning and tissue expression of the mouse ortholog of AIM1, a βγ-crystallin superfamily member Mammalian Genome. 9: 715-720. PMID 9716656 DOI: 10.1007/S003359900852  0.36
1998 Khan J, Parsa NZ, Harada T, Meltzer PS, Carter NP. Detection of Gains and Losses in 18 Meningiomas by Comparative Genomic Hybridization Cancer Genetics and Cytogenetics. 103: 95-100. PMID 9614906 DOI: 10.1016/S0165-4608(97)00394-4  0.326
1997 Su YA, Lee MM, Hutter CM, Meltzer PS. Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas. Oncogene. 15: 1289-1294. PMID 9315096 DOI: 10.1038/Sj.Onc.1201294  0.343
1997 Oda T, Elkahloun AG, Meltzer PS, Chandrasekharappa SC. Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12. Genomics. 43: 376-379. PMID 9268641 DOI: 10.1006/Geno.1997.4820  0.35
1997 Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, Sauter G, Kallioniemi OP, Trent JM, Meltzer PS. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science (New York, N.Y.). 277: 965-8. PMID 9252329 DOI: 10.1126/Science.277.5328.965  0.7
1997 DeYoung KL, Ray ME, Su YA, Anzick SL, Johnstone RW, Trapani JA, Meltzer PS, Trent JM. Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. Oncogene. 15: 453-7. PMID 9242382 DOI: 10.1038/Sj.Onc.1201206  0.708
1997 Oda T, Elkahloun AG, Pike BL, Okajima K, Krantz ID, Genin A, Piccoli DA, Meltzer PS, Spinner NB, Collins FS, Chandrasekharappa SC. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nature Genetics. 16: 235-42. PMID 9207787 DOI: 10.1038/Ng0797-235  0.355
1997 Elkahloun AG, Krizman DB, Wang Z, Hofmann TA, Roe B, Meltzer PS. Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers. Genomics. 42: 295-301. PMID 9192850 DOI: 10.1006/Geno.1997.4727  0.382
1997 Walker RL, Anziano P, Meltzer PS. A PAC containing the human mitochondrial DNA polymerase gamma gene (POLG) maps to chromosome 15q25 Genomics. 40: 376-378. PMID 9119411 DOI: 10.1006/Geno.1996.4580  0.314
1997 Ray ME, Wistow G, Su YA, Meltzer PS, Trent JM. AIM1, a novel non-lens member of the βγ-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma Proceedings of the National Academy of Sciences of the United States of America. 94: 3229-3234. PMID 9096375 DOI: 10.1073/Pnas.94.7.3229  0.326
1997 Meltzer PS, Guan XY, Su YA, Gracia E, Trent JM. Identification of region specific genes by chromosome microdissection Cancer Genetics and Cytogenetics. 93: 29-32. PMID 9062577 DOI: 10.1016/S0165-4608(96)00269-5  0.359
1997 Gracia E, Ray ME, Polymeropoulos MH, Dehejia A, Meltzer PS, Trent JM. Isolation of chromosome-specific ESTs by microdissection-mediated cDNA capture Genome Research. 7: 100-107. PMID 9049628 DOI: 10.1101/Gr.7.2.100  0.335
1997 Wiltshire RN, Duray P, Meltzer PS, Liotta LA, Trent JM. A study of the genetic progression of human cutaneous malignant melanoma by comparative genomic hybridization Cancer Genetics and Cytogenetics. 98: 170. DOI: 10.1016/S0165-4608(97)90321-6  0.31
1996 Berner JM, Forus A, Elkahloun A, Meltzer PS, Fodstad Ø, Myklebost O. Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas Genes, Chromosomes and Cancer. 17: 254-259. PMID 8946207 DOI: 10.1002/(Sici)1098-2264(199612)17:4<254::Aid-Gcc7>3.0.Co;2-2  0.417
1996 Elkahloun AG, Bittner M, Hoskins K, Gemmill R, Meltzer PS. Molecular cytogenetic characterization and physical mapping of 12q13-15 amplification in human cancers. Genes, Chromosomes and Cancer. 17: 205-214. PMID 8946202 DOI: 10.1002/(Sici)1098-2264(199612)17:4<205::Aid-Gcc2>3.0.Co;2-7  0.414
1996 Noble-Topham SE, Burrow SR, Eppert K, Kandel RA, Meltzer PS, Bell RS, Andrulis IL. SAS is amplified predominantly in surface osteosarcoma Journal of Orthopaedic Research. 14: 700-705. PMID 8893761 DOI: 10.1002/Jor.1100140504  0.383
1996 Fischer U, Meltzer P, Meese E. Twelve amplified and expressed genes localized in a single domain in glioma. Human Genetics. 98: 625-628. PMID 8882887 DOI: 10.1007/S004390050271  0.38
1996 Elkahloun AG, Meltzer PS, Guan XY, McNinch JS, Trent JM, de Jong PJ. Isolation of a cosmid sublibrary for a region of chromosome 12 frequently amplified in human cancers using a complex chromosome microdissection probe. Genomics. 31: 343-7. PMID 8838316 DOI: 10.1006/Geno.1996.0057  0.334
1996 Guan XY, Xu J, Anzick SL, Zhang H, Trent JM, Meltzer PS. Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer. Cancer Research. 56: 3446-50. PMID 8758910  0.682
1996 Gracia E, Fischer U, Elkahloun A, Trent JM, Meese E, Meltzer PS. Isolation of genes amplified in human cancers by microdissection mediated cDNA capture Human Molecular Genetics. 5: 595-600. PMID 8733125 DOI: 10.1093/Hmg/5.5.595  0.407
1996 McKeever PE, Dennis TR, Burgess AC, Meltzer PS, Marchuk DA, Trent JM. Chromosome breakpoint at 17q11.2 and insertion of DNA from three different chromosomes in a glioblastoma with exceptional glial fibrillary acidic protein expression. Cancer Genetics and Cytogenetics. 87: 41-7. PMID 8646740 DOI: 10.1016/0165-4608(95)00237-5  0.32
1996 Su AY, Hutter CM, Trent JM, Meltzer PS. Complete sequence analysis of a gene (OS-9) ubiquitously expressed in human tissues and amplified in sarcomas Molecular Carcinogenesis. 15: 270-275. PMID 8634085 DOI: 10.1002/(Sici)1098-2744(199604)15:4<270::Aid-Mc4>3.0.Co;2-K  0.384
1996 Guan X, Horsman D, Zhang HE, Parsa NZ, Meltzer PS, Trent JM. Localization by chromosome microdissection of a recurrent breakpoint region on chromosome 6 in human B-cell lymphoma Blood. 88: 1418-1422. DOI: 10.1182/Blood.V88.4.1418.Bloodjournal8841418  0.324
1995 Jankowski SA, Jong Pd, Meltzer PS. Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas Genomics. 25: 501-506. PMID 7789984 DOI: 10.1016/0888-7543(95)80051-M  0.341
1995 Guan XY, Meltzer PS, Burgess AC, Trent JM. Coverage of chromosome 6 by chromosome microdissection: generation of 14 subregion-specific probes Human Genetics. 95: 637-640. PMID 7789947 DOI: 10.1007/Bf00209479  0.302
1995 Trent JM, Weber B, Guan XY, Zhang J, Collins F, Abel K, Diamond A, Meltzer P. Microdissection and microcloning of chromosomal alterations in human breast cancer. Breast Cancer Research and Treatment. 33: 95-102. PMID 7749145 DOI: 10.1007/Bf00682717  0.4
1995 Piontek K, Müller HW, Fischer U, Götten E, Batzer MA, Meltzer PS, Trent JM, Meese E. Generation and characterization of a human chromosome 6-specific hncDNA library from a somatic cell hybrid Cytogenetic and Genome Research. 69: 273-278. PMID 7698027 DOI: 10.1159/000133978  0.346
1995 Liang BC, Meltzer PS, Guan XY, Trent JM. Gene amplification elucidated by combined chromosomal microdissection and comparative genomic hybridization Cancer Genetics and Cytogenetics. 80: 55-59. PMID 7697633 DOI: 10.1016/0165-4608(94)00153-3  0.394
1995 Nilbert M, Rydholm A, Mitelman F, Meltzer PS, Mandahl N. Characterization of the 12q13-15 amplicon in soft tissue tumors Cancer Genetics and Cytogenetics. 83: 32-36. PMID 7656201 DOI: 10.1016/S0165-4608(95)00016-X  0.367
1995 Moscow JA, Gong M, He R, Sgagias MK, Dixon KH, Anzick SL, Meltzer PS, Cowan KH. Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells. Cancer Research. 55: 3790-4. PMID 7641195  0.691
1995 Guan XY, Cargile CB, Anzick SL, Thompson FH, Meltzer PS, Bittner ML, Taetle R, McGill JR, Trent JM. Chromosome microdissection identifies cryptic sites of DNA sequence amplification in human ovarian carcinoma. Cancer Research. 55: 3380-5. PMID 7614475  0.69
1995 Schutte M, da Costa LT, Hahn SA, Moskaluk C, Hoque AT, Rozenblum E, Weinstein CL, Bittner M, Meltzer PS, Trent JM. Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. Proceedings of the National Academy of Sciences of the United States of America. 92: 5950-4. PMID 7597059 DOI: 10.1073/Pnas.92.13.5950  0.419
1995 Krizman DB, Hofmann TA, DeSilva U, Green ED, Meltzer PS, Trent JM. Identification of 3'-terminal exons from yeast artificial chromosomes Pcr Methods and Applications. 4: 322-326. PMID 7580924 DOI: 10.1101/Gr.4.6.322  0.341
1994 Mitchell DS, Guan X, Meltzer PS. Detection of chromosome 12q amplification in sarcomas by chromosome microdissection and interphase fish. International Journal of Oncology. 5: 787-792. PMID 21559643 DOI: 10.3892/Ijo.5.4.787  0.327
1994 Su YA, Trent JM, Guan XY, Meltzer PS. Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection Proceedings of the National Academy of Sciences of the United States of America. 91: 9121-9125. PMID 8090779 DOI: 10.1073/Pnas.91.19.9121  0.365
1994 Guan XY, Meltzer PS, Trent JM. Rapid Generation of Whole Chromosome Painting Probes (WCPs) by Chromosome Microdissection Genomics. 22: 101-107. PMID 7959755 DOI: 10.1006/Geno.1994.1350  0.306
1994 Guan XY, Meltzer PS, Dalton WS, Trent JM. Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection. Nature Genetics. 8: 155-61. PMID 7842014 DOI: 10.1038/Ng1094-155  0.374
1994 Meese E, Müller H, Göttart E, Zang KD, Batzer MA, Meltzer PS, Trent JM, Piontek K. Isolation and regional assignment of chromosome 6 specific HNCDNA clones to analyze human malignant melanoma Cancer Genetics and Cytogenetics. 77: 182. DOI: 10.1016/0165-4608(94)90366-2  0.315
1991 Meese EU, Meltzer PS, Ferguson PW, Trent JM. Selective amplification of chromosome 6 specific DNA sequences by Alu-based PCR Cancer Genetics and Cytogenetics. 56: 95-96. DOI: 10.1016/0165-4608(91)90373-3  0.304
1986 Kinzler KW, Zehnbauer BA, Brodeur GM, Seeger RC, Trent JM, Meltzer PS, Vogelstein B. Amplification units containing human N-myc and c-myc genes Proceedings of the National Academy of Sciences of the United States of America. 83: 1031-1035. PMID 3006024 DOI: 10.1073/Pnas.83.4.1031  0.355
1985 Trent J, Casper J, Meltzer P, Thompson F, Fogh J. Nonrandom chromosome alterations in rhabdomyosarcoma Cancer Genetics and Cytogenetics. 16: 189-197. PMID 3978590 DOI: 10.1016/0165-4608(85)90045-7  0.313
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