Kenneth E. Ugen - Publications

Affiliations: 
University of South Florida, Tampa, FL, United States 
Area:
Immunology, Microbiology

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Choi H, Kudchodkar SB, Ho M, Reuschel EL, Reynolds E, Xu Z, Bordoloi D, Ugen KE, Tebas P, Kim J, Abdel-Mohsen M, Thangamani S, Weiner DB, Muthumani K. A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus. Plos Neglected Tropical Diseases. 14: e0008788. PMID 33119599 DOI: 10.1371/journal.pntd.0008788  0.385
2020 Zankharia US, Kudchodkar S, Khoshnejad M, Perales-Puchalt A, Choi H, Ho M, Zaidi F, Ugen KE, Kim JJ, Weiner DB, Muthumani K. Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody. Human Vaccines & Immunotherapeutics. 1-9. PMID 32463327 DOI: 10.1080/21645515.2020.1763686  0.347
2019 Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Agarwal S, Van Gorder L, Reed CC, Gulendran G, Ramos S, Broderick KE, Kim JJ, Ugen KE, Kobinger G, Siegel DL, et al. Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge. Human Vaccines & Immunotherapeutics. 1-12. PMID 31799896 DOI: 10.1080/21645515.2019.1688038  0.465
2017 Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, et al. Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody. Cancer Immunology, Immunotherapy : Cii. PMID 28819703 DOI: 10.1007/S00262-017-2042-7  0.319
2017 Cao C, Lin X, Hong Y, Ugen K, Brown B. [P2-056]: AN IMMUNOMODULATORY VACCINE AGAINST Aβ FOR ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P626-P626. DOI: 10.1016/J.Jalz.2017.06.705  0.319
2016 Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, ... ... Ugen KE, et al. In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine. Npj Vaccines. 1: 16021. PMID 29263859 DOI: 10.1038/npjvaccines.2016.21  0.4
2016 Chung C, Ugen KE, Sardesai NY, Weiner DB, Muthumani K. Protocols for Developing Novel Chikungunya Virus DNA Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1426: 311-32. PMID 27233283 DOI: 10.1007/978-1-4939-3618-2_28  0.416
2016 Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya IK, Tingey C, Wise M, Reuschel EL, Chung C, Muthumani A, Sarangan G, Srikanth P, Khan AS, Vijayachari P, Sardesai NY, ... ... Ugen KE, et al. Rapid and long-term immunity elicited by DNA encoded antibody prophylaxis and DNA vaccination against Chikungunya virus. The Journal of Infectious Diseases. PMID 27001960 DOI: 10.1093/Infdis/Jiw111  0.443
2016 Muthumani K, Chung C, Agarwal S, Plyler R, Kudchodkar S, Flingai S, Ugen K, Kim J, Sardesai N, Weiner DB. 401. In Vivo Expression of Plasmid Encoded IgG for PD-1 or LAG3 by Synthetic DNA as a New Tool for Cancer Immunotherapy Molecular Therapy. 24: S159. DOI: 10.1016/S1525-0016(16)33210-5  0.39
2016 Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya I, Sarangan G, Srikanth P, Vijayachari P, Sardesai N, Kim J, Ugen K, Weiner D. Synthetic DNA encoded antibody prophylaxis confers rapid protective immunity in vivo against Chikungunya virus infection International Journal of Infectious Diseases. 45: 185. DOI: 10.1016/J.Ijid.2016.02.432  0.437
2015 Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, ... ... Ugen KE, et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Science Translational Medicine. 7: 301ra132. PMID 26290414 DOI: 10.1016/J.Ijid.2016.02.083  0.457
2015 Ugen KE, Weiner DB. DNA vaccines 2014 meeting: Highlights and overview. Human Vaccines & Immunotherapeutics. 11: 1887-8. PMID 26158530 DOI: 10.1080/21645515.2015.1066947  0.465
2015 Kudrna JJ, Ugen KE. Gene-based vaccines and immunotherapeutic strategies against neurodegenerative diseases: Potential utility and limitations. Human Vaccines & Immunotherapeutics. 11: 1921-6. PMID 26125436 DOI: 10.1080/21645515.2015.1065364  0.406
2015 Vijayachari P, Vedhagiri K, Mallilankaraman K, Mathur PP, Sardesai NY, Weiner DB, Ugen KE, Muthumani K. Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45. Human Vaccines & Immunotherapeutics. 11: 1945-53. PMID 26020621 DOI: 10.1080/21645515.2015.1047117  0.477
2015 Ugen KE, Lin X, Bai G, Liang Z, Cai J, Li K, Song S, Cao C, Sanchez-Ramos J. Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease. Human Vaccines & Immunotherapeutics. 11: 922-30. PMID 25714663 DOI: 10.1080/21645515.2015.1012033  0.353
2014 Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity. Vaccines. 2: 196-215. PMID 26344618 DOI: 10.3390/Vaccines2020196  0.474
2014 Lin X, Bai G, Lin L, Wu H, Cai J, Ugen KE, Cao C. Vaccination induced changes in pro-inflammatory cytokine levels as an early putative biomarker for cognitive improvement in a transgenic mouse model for Alzheimer disease. Human Vaccines & Immunotherapeutics. 10: 2024-31. PMID 25424812 DOI: 10.4161/Hv.28735  0.37
2014 Ugen KE. Review of gene vaccines book. Human Vaccines & Immunotherapeutics. 10: 1926. PMID 25424800 DOI: 10.4161/Hv.28856  0.389
2014 Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, et al. Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model. Cancer Gene Therapy. 21: 507-17. PMID 25394503 DOI: 10.1038/Cgt.2014.56  0.418
2013 Ugen K, Weiner DB. DNA vaccines onward and upward! 20 years and counting! Highlights of the DNA vaccines 2012 meeting. Human Vaccines & Immunotherapeutics. 9: 2038-40. PMID 24131943 DOI: 10.4161/Hv.26628  0.37
2013 Muthumani K, Flingai S, Wise M, Tingey C, Ugen KE, Weiner DB. Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab. Human Vaccines & Immunotherapeutics. 9: 2253-62. PMID 24045230 DOI: 10.4161/Hv.26498  0.433
2013 Bao H, Ramanathan AA, Kawalakar O, Sundaram SG, Tingey C, Bian CB, Muruganandam N, Vijayachari P, Sardesai NY, Weiner DB, Ugen KE, Muthumani K. Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine. Viral Immunology. 26: 75-83. PMID 23409931 DOI: 10.1089/Vim.2012.0061  0.491
2012 Shah K, Connolly RJ, Chapman T, Jaroszeski MJ, Ugen KE. Electrogenetherapy of B16.F10 murine melanoma tumors with an interleukin-28 expressing DNA plasmid. Human Vaccines & Immunotherapeutics. 8: 1722-8. PMID 23151446 DOI: 10.4161/Hv.22560  0.334
2012 Connolly RJ, Chapman T, Hoff AM, Kutzler MA, Jaroszeski MJ, Ugen KE. Non-contact helium-based plasma for delivery of DNA vaccines. Enhancement of humoral and cellular immune responses. Human Vaccines & Immunotherapeutics. 8: 1729-33. PMID 22894954 DOI: 10.4161/Hv.21624  0.469
2012 Ugen KE, Weiner DB. Highlights of the DNA Vaccines 2011 Meeting Human Vaccines and Immunotherapeutics. 8: 1554. DOI: 10.4161/Hv.22752  0.444
2011 Ugen KE, Sardesai N, Weiner DB. DNA vaccines 2010: a gumbo of accomplishment and excitement in New Orleans. Vaccine. 29: 6721-2. PMID 21763382 DOI: 10.1016/J.Vaccine.2011.07.026  0.354
2011 Connolly RJ, Rey JI, Lambert VM, Wegerif G, Jaroszeski MJ, Ugen KE. Enhancement of antigen specific humoral immune responses after delivery of a DNA plasmid based vaccine through a contact-independent helium plasma. Vaccine. 29: 6781-4. PMID 21195804 DOI: 10.1016/J.Vaccine.2010.12.054  0.409
2010 Muthumani K, Lambert VM, Kawalekar O, Heller R, Kim JJ, Weiner DB, Ugen KE. Anti-cancer activity of the HIV accessory molecule viral protein R (Vpr): Delivery as a DNA expression plasmid or biologically active peptides. Vaccine. 28: 2005-10. PMID 20188256 DOI: 10.1016/J.Vaccine.2009.10.060  0.395
2010 Li QY, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. Virus-like peptide vaccines against Abeta N-terminal or C-terminal domains reduce amyloid deposition in APP transgenic mice without addition of adjuvant. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 133-42. PMID 20066498 DOI: 10.1007/S11481-009-9183-1  0.365
2010 Marshall WG, Boone BA, Burgos JD, Gografe SI, Baldwin MK, Danielson ML, Larson MJ, Caretto DR, Cruz Y, Ferraro B, Heller LC, Ugen KE, Jaroszeski MJ, Heller R. Electroporation-mediated delivery of a naked DNA plasmid expressing VEGF to the porcine heart enhances protein expression. Gene Therapy. 17: 419-23. PMID 19956270 DOI: 10.1038/Gt.2009.153  0.633
2010 Kutzler MA, Kraynyak KA, Nagle SJ, Parkinson RM, Zharikova D, Chattergoon M, Maguire H, Muthumani K, Ugen K, Weiner DB. Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo. Gene Therapy. 17: 72-82. PMID 19847203 DOI: 10.1038/Gt.2009.112  0.449
2009 Muthumani K, Lambert VM, Sardesai NY, Kim JJ, Heller R, Weiner DB, Ugen KE. Analysis of the potential for HIV-1 Vpr as an anti-cancer agent. Current Hiv Research. 7: 144-52. PMID 19275583 DOI: 10.2174/157016209787581481  0.409
2009 Muthumani K, Lambert VM, Shanmugam M, Thieu KP, Choo AY, Chung JC, Satishchandran A, Kim JJ, Weiner DB, Ugen KE. Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr). Cancer Biology & Therapy. 8: 180-7. PMID 19029839 DOI: 10.4161/Cbt.8.2.7205  0.372
2008 Fiala M, Singer EJ, Commins D, Mirzapoiazova T, Verin A, Espinosa A, Ugen K, Bernas M, Witte M, Weinand M, Lossinsky AS. HIV-1 Antigens in Neurons of Cocaine-Abusing Patients. The Open Virology Journal. 2: 24-31. PMID 19440461 DOI: 10.2174/1874357900802010024  0.309
2008 Li Q, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. P2-342: Vaccination of amyloid precursor protein transgenic mice with a bacteriophage-based short amyloid-β peptide vaccines without adjuvant induce a strong Th2-type anti-amyloid-β IgG and IgM response and reduce amyloid-β burden Alzheimer's & Dementia. 4: T473-T473. DOI: 10.1016/J.Jalz.2008.05.1419  0.328
2007 McCray AN, Ugen KE, Heller R. Enhancement of anti-melanoma activity of a plasmid expressing HIV-1 Vpr delivered through in vivo electroporation. Cancer Biology & Therapy. 6: 1269-75. PMID 17700061 DOI: 10.4161/Cbt.6.8.4476  0.348
2006 Ugen KE, Nyland SB. Injecting drugs of abuse and immunity: implications for HIV vaccine testing and efficacy. Springer Seminars in Immunopathology. 28: 281-7. PMID 17109182 DOI: 10.1007/S00281-006-0045-0  0.771
2006 McCray AN, Ugen KE, Muthumani K, Kim JJ, Weiner DB, Heller R. Complete regression of established subcutaneous B16 murine melanoma tumors after delivery of an HIV-1 Vpr-expressing plasmid by in vivo electroporation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 647-55. PMID 16950655 DOI: 10.1016/J.Ymthe.2006.06.010  0.353
2006 Ugen KE, Kutzler MA, Marrero B, Westover J, Coppola D, Weiner DB, Heller R. Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation. Cancer Gene Therapy. 13: 969-74. PMID 16763607 DOI: 10.1038/Sj.Cgt.7700973  0.684
2006 Kutzler MA, Cao C, Bai Y, Dong H, Choe PY, Saulino V, McLaughlin L, Whelan A, Choo AY, Weiner DB, Ugen KE. Mapping of immune responses following wild-type and mutant ABeta42 plasmid or peptide vaccination in different mouse haplotypes and HLA Class II transgenic mice. Vaccine. 24: 4630-9. PMID 16157426 DOI: 10.1016/J.Vaccine.2005.08.036  0.398
2006 Kutzler MA, Schoenly KA, Muthumani K, Parkinson RM, Maquire H, Ugen K, Weiner D. Novel strategy for generation of mucosal immune responses against HIV-1 following systemic vaccination Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S30  0.477
2005 MacGregor RR, Boyer JD, Ugen KE, Tebas P, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, Weiner DB. Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips". Vaccine. 23: 2066-73. PMID 15755572 DOI: 10.1016/J.Vaccine.2005.01.010  0.543
2005 Ugen KE, Wang B. Severe acute respiratory syndrome: Pathology, animal models, and vaccine development Dna and Cell Biology. 24: 477-478. DOI: 10.1089/Dna.2005.24.477  0.312
2004 Muthumani K, Choo AY, Hwang DS, Ugen KE, Weiner DB. HIV-1 Vpr: enhancing sensitivity of tumors to apoptosis. Current Drug Delivery. 1: 335-44. PMID 16305395 DOI: 10.2174/1567201043334614  0.369
2004 Cao C, Bai Y, Holloway MJ, Edgeworth RL, Jackson EA, Cotropia J, Ugen KE. Characterization of a novel human anti-HIV-1 gp41 IgM monoclonal antibody designated clone 37. Dna and Cell Biology. 23: 836-41. PMID 15684710 DOI: 10.1089/Dna.2004.23.836  0.456
2004 Li Q, Cao C, Chackerian B, Schiller J, Gordon M, Ugen KE, Morgan D. Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice. Bmc Neuroscience. 5: 21. PMID 15186505 DOI: 10.1186/1471-2202-5-21  0.348
2004 Giri M, Ugen KE, Weiner DB. DNA vaccines against human immunodeficiency virus type 1 in the past decade. Clinical Microbiology Reviews. 17: 370-89. PMID 15084506 DOI: 10.1128/Cmr.17.2.370-389.2004  0.535
2004 Ferrantelli F, Kitabwalla M, Rasmussen RA, Cao C, Chou TC, Katinger H, Stiegler G, Cavacini LA, Bai Y, Cotropia J, Ugen KE, Ruprecht RM. Potent cross-group neutralization of primary human immunodeficiency virus isolates with monoclonal antibodies--implications for acquired immunodeficiency syndrome vaccine. The Journal of Infectious Diseases. 189: 71-4. PMID 14702155 DOI: 10.1086/380102  0.482
2004 McCray AN, Cao C, Muthumani K, Weiner DB, Ugen K, Heller R. 948. Regression of Established Melanoma Tumors through Intratumoral Delivery of HIV-1 Vpr Using In Vivo Electroporation Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.891  0.312
2003 Ugen KE, Heller R. Electroporation as a method for the efficient in vivo delivery of therapeutic genes. Dna and Cell Biology. 22: 753. PMID 14683585 DOI: 10.1089/104454903322624957  0.343
2003 Manoutcharian K, Acero G, Munguia ME, Montero JA, Govezensky T, Cao C, Ugen K, Gevorkian G. Amyloid-beta peptide-specific single chain Fv antibodies isolated from an immune phage display library Journal of Neuroimmunology. 145: 12-17. PMID 14644026 DOI: 10.1016/J.Jneuroim.2003.08.038  0.339
2003 Nyland SB, Cao C, Bai Y, Loughran TP, Ugen KE. Modulation of infection and type 1 cytokine expression parameters by morphine during in vitro coinfection with human T-cell leukemia virus type I and HIV-1. Journal of Acquired Immune Deficiency Syndromes (1999). 32: 406-16. PMID 12640199 DOI: 10.1097/00126334-200304010-00010  0.771
2003 Muthumani K, Bagarazzi M, Conway D, Hwang DS, Manson K, Ciccarelli R, Israel Z, Montefiori DC, Ugen K, Miller N, Kim J, Boyer J, Weiner DB. A Gag-Pol/Env-Rev SIV239 DNA vaccine improves CD4 counts, and reduce viral loads after pathogenic intrarectal SIV(mac)251 challenge in rhesus Macaques. Vaccine. 21: 629-37. PMID 12531331 DOI: 10.1016/S0264-410X(02)00571-6  0.491
2003 Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation The Journal of Neuroscience. 23: 3745-3751. DOI: 10.1523/Jneurosci.23-09-03745.2003  0.309
2002 MacGregor RR, Ginsberg R, Ugen KE, Baine Y, Kang CU, Tu XM, Higgins T, Weiner DB, Boyer JD. T-cell responses induced in normal volunteers immunized with a DNA-based vaccine containing HIV-1 env and rev. Aids (London, England). 16: 2137-43. PMID 12409734 DOI: 10.1097/00002030-200211080-00005  0.549
2002 Gómez-Román VR, Cao C, Bai Y, Santamaría H, Acero G, Manoutcharian K, Weiner DB, Ugen KE, Gevorkian G. Phage-displayed mimotopes recognizing a biologically active anti-HIV-1 gp120 murine monoclonal antibody. Journal of Acquired Immune Deficiency Syndromes (1999). 31: 147-53. PMID 12394792 DOI: 10.1097/00126334-200210010-00004  0.444
2002 Edgeworth RL, San JH, Rosenzweig JA, Nguyen NL, Boyer JD, Ugen KE. Vaccine development against HIV-1: current perspectives and future directions. Immunologic Research. 25: 53-74. PMID 11868934 DOI: 10.1385/Ir:25:1:53  0.488
2001 Wilcock DM, Gordon MN, Ugen KE, Gottschall PE, DiCarlo G, Dickey C, Boyett KW, Jantzen PT, Connor KE, Melachrino J, Hardy J, Morgan D. Number of Abeta inoculations in APP+PS1 transgenic mice influences antibody titers, microglial activation, and congophilic plaque levels. Dna and Cell Biology. 20: 731-6. PMID 11788051 DOI: 10.1089/10445490152717596  0.345
2001 Dickey CA, Morgan DG, Kudchodkar S, Weiner DB, Bai Y, Cao C, Gordon MN, Ugen KE. Duration and specificity of humoral immune responses in mice vaccinated with the Alzheimer's disease-associated beta-amyloid 1-42 peptide. Dna and Cell Biology. 20: 723-9. PMID 11788050 DOI: 10.1089/10445490152717587  0.375
2001 Han TK, Yoder S, Cao C, Ugen KE, Dao ML. Expression of Streptococcus mutans wall-associated protein A gene in Chinese hamster ovary cells: prospect for a dental caries DNA vaccine. Dna and Cell Biology. 20: 595-601. PMID 11747611 DOI: 10.1089/104454901317095016  0.381
2001 Nyland SB, Specter S, Ugen KE. Direct vs. indirect modulation of complex in vitro human retroviral infections by morphine. Advances in Experimental Medicine and Biology. 493: 49-58. PMID 11727780 DOI: 10.1007/0-306-47611-8_6  0.779
2001 Kim JJ, Yang JS, Nottingham LK, Lee DJ, Lee M, Manson KH, Wyand MS, Boyer JD, Ugen KE, Weiner DB. Protection from immunodeficiency virus challenges in rhesus macaques by multicomponent DNA immunization. Virology. 285: 204-17. PMID 11437655 DOI: 10.1006/Viro.2001.0958  0.513
2001 Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. Erratum: correction: Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature. 412: 660-660. DOI: 10.1038/35088102  0.305
2001 Boyer J, Im-Sin J, Kimusa J, Chattergoon M, Chalian A, McCallus D, Conway D, Ugen K, Ginsberg R, Patcuk C, Satishchandran C, Boyer JD, Weiner DB. Engineering a DNA vaccine for HIV-1 Japanese Journal of Chemotherapy. 49: 112.  0.376
2000 Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408: 982-5. PMID 11140686 DOI: 10.1038/35050116  0.329
2000 Boyer JD, Cohen AD, Ugen KE, Edgeworth RL, Bennett M, Shah A, Schumann K, Nath B, Javadian A, Bagarazzi ML, Kim J, Weiner DB. Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids. Aids (London, England). 14: 1515-22. PMID 10983638 DOI: 10.1097/00002030-200007280-00007  0.559
2000 Yoder S, Cao C, Ugen KE, Dao ML. High-level expression of a truncated wall-associated protein A from the dental cariogenic Streptococcus mutans Dna and Cell Biology. 19: 401-408. PMID 10945230 DOI: 10.1089/10445490050085898  0.301
2000 Edgeworth RL, Ugen KE. Immunopathological factors for vertical transmission of HIV-1 Pathobiology. 68: 53-67. PMID 10878502 DOI: 10.1159/000028115  0.465
2000 Dickey C, Ziegner U, Agadjanyan MG, Srikantan V, Refaeli Y, Prabhu A, Sato A, Williams WV, Weiner DB, Ugen KE. Murine monoclonal antibodies biologically active against the amino region of HIV-1 gp120: isolation and characterization. Dna and Cell Biology. 19: 243-52. PMID 10798448 DOI: 10.1089/104454900314519  0.473
2000 Viveros M, Dickey C, Cotropia JP, Gevorkian G, Larralde C, Broliden K, Levi M, Burgess A, Cao C, Weiner DB, Agadjanyan MG, Ugen KE. Characterization of a novel human immunodeficiency virus type 1 neutralizable epitope within the immunodominant region of gp41. Virology. 270: 135-45. PMID 10772986 DOI: 10.1006/Viro.2000.0269  0.352
2000 Kim JJ, Yang JS, VanCott TC, Lee DJ, Manson KH, Wyand MS, Boyer JD, Ugen KE, Weiner DB. Modulation of antigen-specific humoral responses in rhesus macaques by using cytokine cDNAs as DNA vaccine adjuvants. Journal of Virology. 74: 3427-9. PMID 10708463 DOI: 10.1128/Jvi.74.7.3427-3429.2000  0.444
1999 Kim JJ, Nottingham LK, Tsai A, Lee DJ, Maguire HC, Oh J, Dentchev T, Manson KH, Wyand MS, Agadjanyan MG, Ugen KE, Weiner DB. Antigen-specific humoral and cellular immune responses can be modulated in rhesus macaques through the use of IFN-gamma, IL-12, or IL-18 gene adjuvants. Journal of Medical Primatology. 28: 214-23. PMID 10593488 DOI: 10.1111/J.1600-0684.1999.Tb00272.X  0.425
1999 Boyer JD, Kim J, Ugen K, Cohen AD, Ahn L, Schumann K, Lacy K, Bagarazzi ML, Javadian A, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. HIV-1 DNA vaccines and chemokines. Vaccine. 17: S53-64. PMID 10506409 DOI: 10.1016/S0264-410X(99)00235-2  0.51
1999 Bagarazzi ML, Boyer JD, Javadian MA, Chattergoon MA, Shah AR, Cohen AD, Bennett MK, Ciccarelli RB, Ugen KE, Weiner DB. Systemic and mucosal immunity is elicited after both intramuscular and intravaginal delivery of human immunodeficiency virus type 1 DNA plasmid vaccines to pregnant chimpanzees. The Journal of Infectious Diseases. 180: 1351-5. PMID 10479171 DOI: 10.1086/314978  0.535
1999 Kang LC, Kerben MJ, Ugen KE, Specter SC. Modulation of ex vivo cytokine production by splenocytes using in vitro combined therapeutics in murine retroviral model. Dna and Cell Biology. 18: 585-92. PMID 10433557 DOI: 10.1089/104454999315132  0.393
1999 Nyland SB, Specter S, Ugen KE. Morphine effects on HTLV-I infection in the presence or absence of concurrent HIV-1 infection. Dna and Cell Biology. 18: 285-91. PMID 10235111 DOI: 10.1089/104454999315349  0.779
1999 Boyer JD, Chattergoon MA, Ugen KE, Shah A, Bennett M, Cohen A, Nyland S, Lacy KE, Bagarazzi ML, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. Enhancement of cellular immune response in HIV-1 seropositive individuals: A DNA-based trial. Clinical Immunology (Orlando, Fla.). 90: 100-7. PMID 9884357 DOI: 10.1006/Clim.1998.4616  0.78
1998 Sin JI, Kim JJ, Ugen KE, Ciccarelli RB, Higgins TJ, Weiner DB. Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes. European Journal of Immunology. 28: 3530-40. PMID 9842896 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3530::Aid-Immu3530>3.0.Co;2-C  0.438
1998 Bagarazzi ML, Boyer JD, Ugen KE, Javadian MA, Chattergoon M, Shah A, Bennett M, Ciccarelli R, Carrano R, Coney L, Weiner DB. Safety and immunogenicity of HIV-1 DNA constructs in chimpanzees. Vaccine. 16: 1836-41. PMID 9795389 DOI: 10.1016/S0264-410X(98)00178-9  0.502
1998 Ugen KE, Nyland SB, Boyer JD, Vidal C, Lera L, Rasheid S, Chattergoon M, Bagarazzi ML, Ciccarelli R, Higgins T, Baine Y, Ginsberg R, Macgregor RR, Weiner DB. DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans. Vaccine. 16: 1818-21. PMID 9795386 DOI: 10.1016/S0264-410X(98)00180-7  0.803
1998 Noe SN, Nyland SB, Ugen K, Friedman H, Klein TW. Cannabinoid receptor agonists enhance syncytia formation in MT-2 cells infected with cell free HIV-1MN. Advances in Experimental Medicine and Biology. 437: 223-9. PMID 9666275 DOI: 10.1007/978-1-4615-5347-2_25  0.769
1998 Nyland SB, Specter S, Im-Sin J, Ugen KE. Opiate effects on in vitro human retroviral infection. Advances in Experimental Medicine and Biology. 437: 91-100. PMID 9666261 DOI: 10.1007/978-1-4615-5347-2_11  0.774
1998 MacGregor RR, Boyer JD, Ugen KE, Lacy KE, Gluckman SJ, Bagarazzi ML, Chattergoon MA, Baine Y, Higgins TJ, Ciccarelli RB, Coney LR, Ginsberg RS, Weiner DB. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. The Journal of Infectious Diseases. 178: 92-100. PMID 9652427 DOI: 10.1086/515613  0.554
1998 Boyer J, Ugen K, Wang B, Chattergoon M, Tsai A, Merva M, Weiner DB. Induction of a TH1 type cellular immune response to the human immunodeficiency type 1 virus by in vivo DNA inoculation. Developments in Biological Standardization. 92: 169-74. PMID 9554272  0.462
1998 Agadjanyan MG, Chattergoon MA, Petrushina I, Bennett M, Kim J, Ugen KE, Kieber-Emmons T, Weiner DB. Monoclonal antibodies define a cellular antigen involved in HTLV-I infection. Hybridoma. 17: 9-19. PMID 9523233 DOI: 10.1089/Hyb.1998.17.9  0.385
1998 Agadjanyan MG, Wang B, Nyland SB, Weiner DB, Ugen KE. DNA plasmid based vaccination against the oncogenic human T cell leukemia virus type 1. Current Topics in Microbiology and Immunology. 226: 175-92. PMID 9479842 DOI: 10.1007/978-3-642-80475-5_11  0.772
1997 Agadjanyan MG, Trivedi NN, Kudchodkar S, Bennett M, Levine W, Lin A, Boyer J, Levy D, Ugen KE, Kim JJ, Weiner DB. An HIV type 2 DNA vaccine induces cross-reactive immune responses against HIV type 2 and SIV. Aids Research and Human Retroviruses. 13: 1561-72. PMID 9430248 DOI: 10.1089/Aid.1997.13.1561  0.558
1997 Boyer JD, Ugen KE, Chattergoon M, Wang B, Shah A, Agadjanyan M, Bagarazzi ML, Javadian A, Carrano R, Coney L, Williams WV, Weiner DB. DNA vaccination as anti-human immunodeficiency virus immunotherapy in infected chimpanzees. The Journal of Infectious Diseases. 176: 1501-9. PMID 9395361 DOI: 10.1086/514148  0.563
1997 Ugen KE, Boyer JD, Wang B, Bagarazzi M, Javadian A, Frost P, Merva MM, Agadjanyan MG, Nyland S, Williams WV, Coney L, Ciccarelli R, Weiner DB. Nucleic acid immunization of chimpanzees as a prophylactic/immunotherapeutic vaccination model for HIV-1: prelude to a clinical trial. Vaccine. 15: 927-30. PMID 9234550 DOI: 10.1016/S0264-410X(96)00254-X  0.797
1997 Wang B, Dang K, Agadjanyan MG, Srikantan V, Li F, Ugen KE, Boyer J, Merva M, Williams WV, Weiner DB. Mucosal immunization with a DNA vaccine induces immune responses against HIV-1 at a mucosal site. Vaccine. 15: 821-5. PMID 9234524 DOI: 10.1016/S0264-410X(96)00259-9  0.546
1997 Boyer JD, Ugen KE, Wang B, Agadjanyan M, Gilbert L, Bagarazzi ML, Chattergoon M, Frost P, Javadian A, Williams WV, Refaeli Y, Ciccarelli RB, McCallus D, Coney L, Weiner DB. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nature Medicine. 3: 526-32. PMID 9142121 DOI: 10.1038/Nm0597-526  0.554
1997 Mahalingam S, MacDonald B, Ugen KE, Ayyavoo V, Agadjanyan MG, Williams WV, Weiner DB. In vitro and in vivo tumor growth suppression by HIV-1 Vpr. Dna and Cell Biology. 16: 137-43. PMID 9052734 DOI: 10.1089/Dna.1997.16.137  0.391
1997 Ugen KE, Srikantan V, Goedert JJ, Nelson RP, Williams WV, Weiner DB. Vertical transmission of human immunodeficiency virus type 1: seroreactivity by maternal antibodies to the carboxy region of the gp41 envelope glycoprotein. The Journal of Infectious Diseases. 175: 63-9. PMID 8985197 DOI: 10.1093/Infdis/175.1.63  0.431
1996 Boyer JD, Wang B, Ugen KE, Agadjanyan M, Javadian A, Frost P, Dang K, Carrano RA, Ciccarelli R, Coney L, Williams WV, Weiner DB. In vivo protective anti-HIV immune responses in non-human primates through DNA immunization. Journal of Medical Primatology. 25: 242-50. PMID 8892046 DOI: 10.1111/J.1600-0684.1996.Tb00022.X  0.574
1996 Ayyavoo V, Ugen KE, Fernandes LS, Goedert JJ, Rubinstein A, Williams WV, Weiner DB. Analysis of genetic heterogeneity, antigenicity, and biological characteristics of HIV-1 in a maternal transmitter and nontransmitter patient pair. Dna and Cell Biology. 15: 571-80. PMID 8756338 DOI: 10.1089/Dna.1996.15.571  0.444
1996 Cotropia J, Ugen KE, Kliks S, Broliden K, Broliden PA, Hoxie JA, Srikantan V, Williams WV, Weiner DB. A human monoclonal antibody to HIV-1 gp41 with neutralizing activity against diverse laboratory isolates. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 12: 221-32. PMID 8673526 DOI: 10.1097/00042560-199607000-00002  0.466
1995 Wang B, Boyer JD, Ugen KE, Srikantan V, Ayyaroo V, Agadjanyan MG, Williams WV, Newman M, Coney L, Carrano R. Nucleic acid-based immunization against HIV-I: induction of protective in vivo immune responses Aids (London, England). 9: S159-170. PMID 8819582  0.354
1995 Ugen KE, Noble CD. Vertical transmission of HIV-1 infection. Diagnosis and prevention Journal of the Florida Medical Association. 82: 825-826. PMID 8568507  0.376
1995 Wang B, Boyer J, Srikantan V, Ugen K, Agadjanian M, Merva M, Gilbert L, Dang K, McCallus D, Moelling K, Carrano R, Williams WV, Coney L, Weiner DB. DNA inoculation induces cross clade anti-HIV-1 responses Annals of the New York Academy of Sciences. 772: 186-197. PMID 8546392 DOI: 10.1111/J.1749-6632.1995.Tb44744.X  0.569
1995 Wang B, Boyer J, Srikantan V, Ugen K, Gilbert L, Phan C, Dang K, Merva M, Agadjanyan MG, Newman M, Carrano R, McCallus D, Coney L, Villiams WV, Weiner DB. Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation Virology. 211: 102-112. PMID 7645204 DOI: 10.1006/Viro.1995.1383  0.561
1995 Wang B, Merva M, Dang K, Ugen KE, Williams WV, Weiner DB. Immunization by direct DNA inoculation induces rejection of tumor cell challenge. Human Gene Therapy. 6: 407-18. PMID 7612698 DOI: 10.1089/Hum.1995.6.4-407  0.395
1994 Agadjanyan MG, Ugen KE, Wang B, Williams WV, Weiner DB. Identification of an 80-kilodalton membrane glycoprotein important for human T-cell leukemia virus type I and type II syncytium formation and infection Journal of Virology. 68: 485-493. PMID 8254759 DOI: 10.1128/Jvi.68.1.485-493.1994  0.36
1994 Coney L, Wang B, Ugen KE, Boyer J, McCallus D, Srikantan V, Agadjanyan M, Pachuk CJ, Herold K, Merva M, Gilbert L, Deng K, Moelling K, Newman M, Williams WV, et al. Facilitated DNA inoculation induces anti-HIV-1 immunity in vivo Vaccine. 12: 1545-1550. PMID 7879423 DOI: 10.1016/0264-410X(94)90082-5  0.56
1994 Wang B, Merva M, Dang K, Ugen KE, Boyer J, Williams WV, Weiner DB. DNA inoculation induces protective in vivo immune responses against cellular challenge with HIV-1 antigen-expressing cells Aids Research and Human Retroviruses. 10: S35-S41. PMID 7865331  0.455
1994 Srikantan V, Wang B, Satre MA, Ugen KE, Dang K, Scales F, Godillot AP, Williams WV, Weiner DB. Cloning and biological characterization of human single-chain Fv fragments that mediate neutralization of HIV-1 Aids. 8: 1525-1532. PMID 7848589 DOI: 10.1097/00002030-199411000-00002  0.488
1994 Ugen KE, Von Feldt JM, Weiner DB, Ziegner UHM. Diagnosis and prediction of pediatric HIV-1 infection and AIDS: Current status Journal of Clinical Laboratory Analysis. 8: 309-314. PMID 7807285 DOI: 10.1002/Jcla.1860080509  0.492
1994 Ugen KE, Wang B, Ayyavoo V, Agadjanyan M, Boyer J, Li F, Kudchodkar S, Lin J, Merva M, Fernandes L, Williams WV, Weiner DB. DNA inoculation as a novel vaccination method against human retroviruses with rheumatic disease associations Immunologic Research. 13: 154-162. PMID 7775806 DOI: 10.1007/Bf02918276  0.553
1994 Eaton AM, Ugen KE, Weiner DB, Wildes T, Levy JA. An anti-gp41 human monoclonal antibody that enhances HIV-1 infection in the absence of complement. Aids Research and Human Retroviruses. 10: 13-8. PMID 7514015 DOI: 10.1089/Aid.1994.10.13  0.494
1994 Sato AI, Balamuth FB, Ugen KE, Williams WV, Weiner DB. Identification of CD7 glycoprotein as an accessory molecule in HIV-1- mediated syncytium formation and cellfree infection Journal of Immunology. 152: 5142-5152. PMID 7513730  0.305
1993 Wang B, Ugen KE, Srikantan V, Agadjanyan MG, Dang K, Refaeli Y, Sato AI, Boyer J, Williams WV, Weiner DB. Gene inoculation generates immune responses against human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 90: 4156-4160. PMID 8483929 DOI: 10.1073/Pnas.90.9.4156  0.566
1993 Bhat S, Mettus RV, Reddy EP, Ugen KE, Srikanthan V, Williams WV, Weiner DB. The galactosyl ceramide/sulfatide receptor binding region of HIV-1 gp120 maps to amino acids 206-275 Aids Research and Human Retroviruses. 9: 175-181. PMID 8457384 DOI: 10.1089/Aid.1993.9.175  0.342
1993 Wang B, Agadjanyan MG, Srikantan V, Ugen KE, Hall W, Kaplan MH, Dang K, Williams WV, Weiner DB. Molecular cloning, expression, and biological characterization of an HTLV- II envelope glycoprotein: HIV-1 expression is permissive for HTLV-II-induced cell fusion Aids Research and Human Retroviruses. 9: 849-860. PMID 8257634 DOI: 10.1089/Aid.1993.9.849  0.449
1993 Wang B, Boyer J, Srikantan V, Coney L, Carrano R, Phan C, Merva M, Dang K, Agadjanan M, Gilbert L, Ugen KE, Williams WV, Weiner DB. DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates Dna and Cell Biology. 12: 799-805. PMID 8216851 DOI: 10.1089/Dna.1993.12.799  0.523
1993 Ugen KE, Goedert JJ, Weiner DB. Maternal antibodies against HIV-1 envelope glycoprotein: Model to evaluate vertical transmission/potential vaccine efficacy Archives of Std/Hiv Research. 7: 223-228.  0.438
1992 Ugen KE, Goedert JJ, Boyer J, Refaeli Y, Frank I, Williams WV, Willoughby A, Landesman S, Mendez H, Rubinstein A. Vertical transmission of human immunodeficiency virus (HIV) infection. Reactivity of maternal sera with glycoprotein 120 and 41 peptides from HIV type 1. The Journal of Clinical Investigation. 89: 1923-30. PMID 1601999 DOI: 10.1172/Jci115798  0.503
1992 Ugen KE, McCallus DE, Von Feldt JM, Williams WV, Greene MI, Weiner DB. Ocular tissue involvement in HIV infection: Immunological and pathological aspects Immunologic Research. 11: 141-153. PMID 1431423 DOI: 10.1007/Bf02918619  0.464
1992 Kieber-Emmons T, Krowka JF, Boyer J, Ugen KE, Williams WV, Morrow WJW, Weiner DB. Immunological characteristics of the putative CD4-binding site of the HIV-1 envelope protein Pathobiology. 60: 187-194. PMID 1388715 DOI: 10.1159/000163722  0.4
1992 Osther K, Wiik A, Black F, Skinhøj P, Kellermann G, Ugen KE, Williams WV, Weiner DB. PASSHIV-1 treatment of patients with HIV-1 infection. A preliminary report of a Phase I trial of hyperimmune porcine immunoglobulin to HIV-1 Aids. 6: 1457-1464. PMID 1362878 DOI: 10.1097/00002030-199212000-00006  0.44
1992 McCallus DE, Ugen KE, Sato AI, Williams WV, Weiner DB. Construction of a recombinant bacterial human CD4 expression system producing a bioactive CD4 molecule Viral Immunology. 5: 163-172. PMID 1319711 DOI: 10.1089/Vim.1992.5.163  0.319
1991 Osther K, Kellermann G, Ugen KE, Williams WV, Weiner DB. Protective humoral immune responses to the human immunodeficiency virus induced in immunized pigs: A possible source of therapeutic immunoglobulin preparations Hybridoma. 10: 673-683. PMID 1816071 DOI: 10.1089/Hyb.1991.10.673  0.532
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