David Oupicky - Publications

Affiliations: 
Biomedical Engineering Wayne State University, Detroit, MI, United States 
Area:
Biomedical Engineering

49/175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wu P, Luo X, Wu H, Zhang Q, Wang K, Sun M, Oupicky D. Combined Hydrophobization of Polyethylenimine with Cholesterol and Perfluorobutyrate Improves siRNA Delivery. Bioconjugate Chemistry. PMID 31967460 DOI: 10.1021/Acs.Bioconjchem.9B00834  0.338
2019 Li Z, Chen G, Ding L, Wang Y, Zhu C, Wang K, Li J, Sun M, Oupicky D. Increased Survival by Pulmonary Treatment of Established Lung Metastases with Dual STAT3/CXCR4 Inhibition by siRNA Nanoemulsions. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31481310 DOI: 10.1016/J.Ymthe.2019.08.008  0.306
2019 Zou Y, Wan L, Blacklock J, Xie L, Carroll S, Oupicky D, Mao G. In Situ AFM Analysis Investigating Disassembly of DNA Nanoparticles and Nanofilms. Methods in Molecular Biology (Clifton, N.J.). 1943: 199-209. PMID 30838618 DOI: 10.1007/978-1-4939-9092-4_13  0.325
2018 Zhou Z, Zhang Q, Zhang M, Li H, Chen G, Qian C, Oupicky D, Sun M. ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy. Theranostics. 8: 4604-4619. PMID 30279726 DOI: 10.7150/Thno.26889  0.375
2018 Wu P, Luo X, Wu H, Yu F, Wang K, Sun M, Oupicky D. Cholesterol Modification Enhances Antimetastatic Activity and siRNA Delivery Efficacy of Poly(ethylenimine)-Based CXCR4 Antagonists. Macromolecular Bioscience. e1800234. PMID 30259651 DOI: 10.1002/Mabi.201800234  0.356
2018 Zhou Z, Li C, Zhang M, Zhang Q, Qian C, Oupicky D, Sun M. Charge and Assembly Reversible Micelles Fuelled by Intracellular ATP for Improved siRNA Transfection. Acs Applied Materials & Interfaces. PMID 30179452 DOI: 10.1021/Acsami.8B13300  0.38
2018 Zhou Z, Zhang M, Liu Y, Li C, Zhang Q, Oupicky D, Sun M. Reversible Covalent-Crosslinked Polycations with Enhanced Stability and ATP-Responsive Behavior for Improved siRNA Delivery. Biomacromolecules. PMID 30081638 DOI: 10.1021/Acs.Biomac.8B00922  0.364
2018 Yang X, Li H, Qian C, Guo Y, Li C, Gao F, Yang Y, Wang K, Oupicky D, Sun M. Near-infrared light-activated IR780-loaded liposomes for anti-tumor angiogenesis and Photothermal therapy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29981460 DOI: 10.1016/J.Nano.2018.06.011  0.324
2018 Li H, Yang X, Gao F, Qian C, Li C, Oupicky D, Sun M. Bioreduction-ruptured nanogel for switch on/off release of Bcl2 siRNA in breast tumor therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29499219 DOI: 10.1016/J.Jconrel.2018.02.036  0.403
2018 Kularatne RN, Washington KE, Bulumulla C, Calubaquib EL, Biewer MC, Oupicky D, Stefan MC. Histone Deacetylase Inhibitor (HDACi) Conjugated Polycaprolactone for Combination Cancer Therapy. Biomacromolecules. PMID 29485283 DOI: 10.1021/Acs.Biomac.8B00221  0.375
2018 Li H, Zhou Z, Zhang F, Guo Y, Yang X, Jiang H, Tan F, Oupicky D, Sun M. A networked swellable dextrin nanogels loading Bcl2 siRNA for melanoma tumor therapy Nano Research. 11: 4627-4642. DOI: 10.1007/S12274-018-2044-6  0.359
2017 Li H, Yang X, Zhou Z, Wang K, Li C, Qiao H, Oupicky D, Sun M. Near-infrared light-triggered drug release from a multiple lipid carrier complex using an all-in-one strategy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28666728 DOI: 10.1016/J.Jconrel.2017.06.029  0.334
2017 Senevirathne SA, Washington KE, Miller JB, Biewer MC, Oupicky D, Siegwart DJ, Stefan MC. HDAC Inhibitor Conjugated Polymeric Prodrug Micelles for Doxorubicin Delivery. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 5: 2106-2114. PMID 28630710 DOI: 10.1039/C6Tb03038F  0.363
2017 Wani A, Savithra GHL, Abyad A, Kanvinde S, Li J, Brock S, Oupický D. Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells. Scientific Reports. 7: 2274. PMID 28536462 DOI: 10.1038/S41598-017-02531-4  0.498
2017 Zhang F, Gong S, Wu J, Li H, Oupicky D, Sun M. CXCR4-targeted and Redox Responsive Dextrin Nanogel for Metastatic Breast Cancer Therapy. Biomacromolecules. PMID 28445650 DOI: 10.1021/Acs.Biomac.7B00208  0.303
2017 Murray-Stewart T, Ferrari E, Xie Y, Yu F, Marton LJ, Oupicky D, Casero RA. Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047. Plos One. 12: e0175917. PMID 28423064 DOI: 10.1371/Journal.Pone.0175917  0.368
2017 Zhou Z, Li H, Wang K, Guo Q, Li C, Jiang HL, Hu Y, Oupicky D, Sun M. Bioreducible Cross-Linked Hyaluronic Acid/Calcium Phosphate Hybrid Nanoparticles for Specific Delivery of siRNA in Melanoma Tumor Therapy. Acs Applied Materials & Interfaces. PMID 28393529 DOI: 10.1021/Acsami.6B15347  0.361
2017 Li H, Wang K, Yang X, Zhou Y, Ping Q, Oupicky D, Sun M. Dual-function nanostructured lipid carriers to deliver IR780 for breast cancer treatment: anti-metastatic and photothermal anti-tumor therapy. Acta Biomaterialia. PMID 28159715 DOI: 10.1016/J.Actbio.2017.01.070  0.327
2017 Zhou Z, Li H, Oupicky D, Sun M. Target-specific delivery of Bcl2 siRNA by bioreducible crosslinked hyaluronic acid/ calcium phosphate hybrid nanoparticles for melanoma tumor therapy Journal of Controlled Release. 259: e188. DOI: 10.1016/J.Jconrel.2017.03.369  0.327
2017 Li H, Zhou Z, Zhang F, Yang X, Oupicky D, Sun M. Reduction-responsive disulfide cross-linked dextrin nanogel mediated Bcl-2 siRNA delivery for anticancer therapy Journal of Controlled Release. 259: e52. DOI: 10.1016/J.Jconrel.2017.03.126  0.308
2016 Oupicky D. Utilizing polydrug and polymeric drug concepts in development of nucleic acid delivery vectors Nanomedicine: Nanotechnology, Biology and Medicine. 12: 449. DOI: 10.1016/J.Nano.2015.12.003  0.361
2015 Senevirathne SA, Boonsith S, Oupicky D, Biewer MC, Stefan MC. Synthesis and characterization of valproic acid ester pro-drug micelles via an amphiphilic polycaprolactone block copolymer design Polymer Chemistry. 6: 2386-2389. DOI: 10.1039/C4Py01808G  0.349
2013 Zou Y, Wan L, Blacklock J, Oupicky D, Mao G. In situ AFM analysis investigating disassembly of DNA nanoparticles and nano-films. Methods in Molecular Biology (Clifton, N.J.). 948: 183-93. PMID 23070771 DOI: 10.1007/978-1-62703-140-0_13  0.427
2013 You YZ, Yan JJ, Yu ZQ, Oupicky D. Synthesis of bioreducible polycations with controlled topologies. Methods in Molecular Biology (Clifton, N.J.). 948: 121-32. PMID 23070767 DOI: 10.1007/978-1-62703-140-0_9  0.358
2012 Wani A, Muthuswamy E, Savithra GH, Mao G, Brock S, Oupický D. Surface functionalization of mesoporous silica nanoparticles controls loading and release behavior of mitoxantrone. Pharmaceutical Research. 29: 2407-18. PMID 22555380 DOI: 10.1007/S11095-012-0766-9  0.464
2012 Li J, Manickam DS, Chen J, Oupicky D. Effect of cell membrane thiols and reduction-triggered disassembly on transfection activity of bioreducible polyplexes. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 173-80. PMID 22406090 DOI: 10.1016/J.Ejps.2012.02.020  0.443
2012 Dewal MB, Wani AS, Vidaillac C, Oupický D, Rybak MJ, Firestine SM. Thieno[2,3-d]pyrimidinedione derivatives as antibacterial agents. European Journal of Medicinal Chemistry. 51: 145-53. PMID 22405289 DOI: 10.1016/J.Ejmech.2012.02.035  0.421
2012 Oupicky D, Read ML, Bettinger T. Stabilization of Polycation-DNA Complexes by Surface Modification with Hydrophilic Polymers. Methods in Molecular Medicine. 65: 61-78. PMID 21318745 DOI: 10.1385/1-59259-139-6:61  0.313
2010 Rahbek UL, Nielsen AF, Dong M, You Y, Chauchereau A, Oupicky D, Besenbacher F, Kjems J, Howard KA. Bioresponsive hyperbranched polymers for siRNA and miRNA delivery. Journal of Drug Targeting. 18: 812-20. PMID 20979442 DOI: 10.3109/1061186X.2010.527982  0.332
2010 Oupicky D. Polymeric biomaterials for gene and drug delivery. Pharmaceutical Research. 27: 2517-9. PMID 20967489 DOI: 10.1007/S11095-010-0302-8  0.338
2010 Bhattarai SR, Muthuswamy E, Wani A, Brichacek M, Castañeda AL, Brock SL, Oupicky D. Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine. Pharmaceutical Research. 27: 2556-68. PMID 20730557 DOI: 10.1007/S11095-010-0245-0  0.612
2010 Andersen MØ, Lichawska A, Arpanaei A, Rask Jensen SM, Kaur H, Oupicky D, Besenbacher F, Kingshott P, Kjems J, Howard KA. Surface functionalisation of PLGA nanoparticles for gene silencing. Biomaterials. 31: 5671-7. PMID 20434215 DOI: 10.1016/J.Biomaterials.2010.03.069  0.313
2010 Blacklock J, Mao G, Oupický D, Möhwald H. DNA release dynamics from bioreducible layer-by-layer films. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 8597-605. PMID 20131916 DOI: 10.1021/La904673R  0.306
2009 Zhou QH, You YZ, Wu C, Huang Y, Oupický D. Cyclic RGD-targeting of reversibly stabilized DNA nanoparticles enhances cell uptake and transfection in vitro. Journal of Drug Targeting. 17: 364-73. PMID 19263264 DOI: 10.1080/10611860902807046  0.302
2009 Blacklock J, You YZ, Zhou QH, Mao G, Oupický D. Gene delivery in vitro and in vivo from bioreducible multilayered polyelectrolyte films of plasmid DNA. Biomaterials. 30: 939-50. PMID 19013638 DOI: 10.1016/J.Biomaterials.2008.10.012  0.304
2009 Kakade S, Manickam DS, Handa H, Mao G, Oupický D. Transfection activity of layer-by-layer plasmid DNA/poly(ethylenimine) films deposited on PLGA microparticles. International Journal of Pharmaceutics. 365: 44-52. PMID 18786622 DOI: 10.1016/J.Ijpharm.2008.08.019  0.3
2008 Wan L, Manickam DS, Oupický D, Mao G. DNA release dynamics from reducible polyplexes by atomic force microscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 12474-82. PMID 18839970 DOI: 10.1021/La802088Y  0.305
2008 Oupicky D. Design and development strategies of polymer materials for drug and gene delivery applications. Advanced Drug Delivery Reviews. 60: 957. PMID 18378351 DOI: 10.1016/J.Addr.2008.02.003  0.341
2007 You YZ, Manickam DS, Zhou QH, Oupický D. Reducible poly(2-dimethylaminoethyl methacrylate): synthesis, cytotoxicity, and gene delivery activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 122: 217-25. PMID 17574292 DOI: 10.1016/j.jconrel.2007.04.020  0.324
2007 Howard KA, Dong M, Oupicky D, Bisht HS, Buss C, Besenbacher F, Kjems J. Nanocarrier stimuli-activated gene delivery. Small (Weinheim An Der Bergstrasse, Germany). 3: 54-7. PMID 17294468 DOI: 10.1002/Smll.200600328  0.333
2007 Blacklock J, Handa H, Soundara Manickam D, Mao G, Mukhopadhyay A, Oupický D. Disassembly of layer-by-layer films of plasmid DNA and reducible TAT polypeptide. Biomaterials. 28: 117-24. PMID 16962657 DOI: 10.1016/J.Biomaterials.2006.08.035  0.644
2007 Dong M, Howard KA, Oupicky D, Bisht H, Kjems J, Besenbacher F. Visualization of thermally activated nanocarriers using in situ atomic force microscopy Nanotechnology. 18. DOI: 10.1088/0957-4484/18/18/185501  0.301
2006 Soundara Manickam D, Oupický D. Polyplex gene delivery modulated by redox potential gradients. Journal of Drug Targeting. 14: 519-26. PMID 17050118 DOI: 10.1080/10611860600834409  0.668
2006 Bisht HS, Manickam DS, You Y, Oupicky D. Temperature-controlled properties of DNA complexes with poly(ethylenimine)-graft-poly(N-isopropylacrylamide). Biomacromolecules. 7: 1169-78. PMID 16602735 DOI: 10.1021/Bm0509927  0.372
2005 Oupicky D, Bisht HS, Manickam DS, Zhou QH. Stimulus-controlled delivery of drugs and genes. Expert Opinion On Drug Delivery. 2: 653-65. PMID 16296792 DOI: 10.1517/17425247.2.4.653  0.374
2005 Zhou QH, Miller DL, Carlisle RC, Seymour LW, Oupicky D. Ultrasound-enhanced transfection activity of HPMA-stabilized DNA polyplexes with prolonged plasma circulation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 106: 416-27. PMID 15967534 DOI: 10.1016/J.Jconrel.2005.05.002  0.433
2005 Soundara Manickam D, Bisht HS, Wan L, Mao G, Oupicky D. Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 102: 293-306. PMID 15653153 DOI: 10.1016/J.Jconrel.2004.09.018  0.658
2005 Howard KA, Liu X, Oupicky D, Zoffmann S, Besenbacher F, Kjems J. Small interfering RNA delivery and gene silencing using polymeric nanocarrier systems Nanobiotechnology. 1: 299-299. DOI: 10.1007/S12030-005-0050-8  0.359
2002 Ward CM, Pechar M, Oupicky D, Ulbrich K, Seymour LW. Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. The Journal of Gene Medicine. 4: 536-47. PMID 12221647 DOI: 10.1002/Jgm.296  0.313
Low-probability matches (unlikely to be authored by this person)
1998 Toncheva V, Wolfert MA, Dash PR, Oupicky D, Ulbrich K, Seymour LW, Schacht EH. Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochimica Et Biophysica Acta. 1380: 354-68. PMID 9555094 DOI: 10.1016/S0304-4165(98)00004-X  0.298
2018 Chen G, Wang Y, Wu P, Zhou Y, Yu F, Zhu C, Li Z, Hang Y, Wang K, Li J, Sun M, Oupicky D. Reversibly Stabilized Polycation Nanoparticles for Combination Treatment of Early- and Late-Stage Metastatic Breast Cancer. Acs Nano. PMID 29985577 DOI: 10.1021/Acsnano.8B01482  0.296
2007 Wan L, Bisht HS, You YZ, Oupicky D, Mao G. Temperature-reversible ultrathin films of N-isopropylacrylamide terpolymer adsorbed at the solid-liquid interface. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 12159-66. PMID 17963410 DOI: 10.1021/La701819Q  0.292
2008 Rahbek UL, Howard KA, Oupicky D, Manickam DS, Dong M, Nielsen AF, Hansen TB, Besenbacher F, Kjems J. Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides. The Journal of Gene Medicine. 10: 81-93. PMID 18000993 DOI: 10.1002/Jgm.1120  0.291
2006 Manickam DS, Oupický D. Multiblock reducible copolypeptides containing histidine-rich and nuclear localization sequences for gene delivery. Bioconjugate Chemistry. 17: 1395-403. PMID 17105216 DOI: 10.1021/bc060104k  0.289
2010 Regmi R, Bhattarai SR, Sudakar C, Wani AS, Cunningham R, Vaishnava PP, Naik R, Oupicky D, Lawes G. Hyperthermia controlled rapid drug release from thermosensitive magnetic microgels Journal of Materials Chemistry. 20: 6158-6163. DOI: 10.1039/C0Jm00844C  0.284
2005 Parker AL, Fisher KD, Oupicky D, Read ML, Nicklin SA, Baker AH, Seymour LW. Enhanced gene transfer activity of peptide-targeted gene-delivery vectors. Journal of Drug Targeting. 13: 39-51. PMID 15848953 DOI: 10.1080/10611860400020449  0.282
2009 Wan L, You Y, Zou Y, Oupický D, Mao G. DNA release dynamics from bioreducible poly(amido amine) polyplexes. The Journal of Physical Chemistry. B. 113: 13735-41. PMID 19522487 DOI: 10.1021/Jp901835U  0.282
2002 Parker AL, Oupicky D, Dash PR, Seymour LW. Methodologies for monitoring nanoparticle formation by self-assembly of DNA with poly(l-lysine). Analytical Biochemistry. 302: 75-80. PMID 11846378 DOI: 10.1006/Abio.2001.5507  0.278
2015 Zhu Y, Li J, Kanvinde S, Lin Z, Hazeldine S, Singh RK, Oupický D. Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer. Molecular Pharmaceutics. 12: 332-41. PMID 25153488 DOI: 10.1021/mp500469n  0.276
2002 Oupicky D, Ogris M, Howard KA, Dash PR, Ulbrich K, Seymour LW. Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 463-72. PMID 11945074 DOI: 10.1006/Mthe.2002.0568  0.274
2017 Chen G, Wang K, Wang Y, Wu P, Sun M, Oupický D. Fluorination Enhances Serum Stability of Bioreducible Poly(amido amine) Polyplexes and Enables Efficient Intravenous siRNA Delivery. Advanced Healthcare Materials. PMID 29280311 DOI: 10.1002/adhm.201700978  0.273
2018 Chen Y, Li J, Oupický D. Conjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In Vivo. Bioconjugate Chemistry. PMID 29338191 DOI: 10.1021/acs.bioconjchem.7b00622  0.271
2009 Zhou QH, Wu C, Manickam DS, Oupický D. Evaluation of pharmacokinetics of bioreducible gene delivery vectors by real-time PCR. Pharmaceutical Research. 26: 1581-9. PMID 19240986 DOI: 10.1007/s11095-009-9847-9  0.27
2008 Zhang H, Thomas R, Oupicky D, Peng F. Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on cisplatin-resistant neuroblastoma cells. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 47-55. PMID 17909866 DOI: 10.1007/S00775-007-0299-6  0.269
2007 You YZ, Manickam DS, Zhou QH, Oupický D. A versatile approach to reducible vinyl polymers via oxidation of telechelic polymers prepared by reversible addition fragmentation chain transfer polymerization. Biomacromolecules. 8: 2038-44. PMID 17518443 DOI: 10.1021/Bm0702049  0.268
2005 Bisht HS, Wan L, Mao G, Oupicky D. pH-Controlled association of PEG-containing terpolymers of N-isopropylacrylamide and 1-vinylimidazole Polymer. 46: 7945-7952. DOI: 10.1016/J.Polymer.2005.06.080  0.268
2013 Yuan J, Zhang H, Kaur H, Oupicky D, Peng F. Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymer targeting tumor angiogenesis: tumor localization visualized by positron emission tomography. Molecular Imaging. 12: 203-12. PMID 23490439 DOI: 10.2310/7290.2012.00038  0.264
2017 Sun M, Li J, Zhang C, Xie Y, Qiao H, Su Z, Oupický D, Ping Q. Arginine-Modified Nanostructured Lipid Carriers with Charge-Reversal and pH-Sensitive Membranolytic Properties for Anticancer Drug Delivery. Advanced Healthcare Materials. PMID 28187243 DOI: 10.1002/adhm.201600693  0.264
2000 Dash PR, Read ML, Fisher KD, Howard KA, Wolfert M, Oupicky D, Subr V, Strohalm J, Ulbrich K, Seymour LW. Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin. The Journal of Biological Chemistry. 275: 3793-802. PMID 10660529 DOI: 10.1074/Jbc.275.6.3793  0.263
2020 Li Z, Wang Y, Shen Y, Qian C, Oupicky D, Sun M. Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti-PD-L1 immunotherapy. Science Advances. 6: eaaz9240. PMID 32440550 DOI: 10.1126/Sciadv.Aaz9240  0.263
2007 Yuan J, You Y, Lu X, Muzik O, Oupicky D, Peng F. Synthesis of Poly[APMA]-DOTA-64Cu conjugates for interventional radionuclide therapy of prostate cancer: assessment of intratumoral retention by micro-positron emission tomography. Molecular Imaging. 6: 10-7. PMID 17311761 DOI: 10.2310/7290.2006.00030  0.261
2005 Read ML, Singh S, Ahmed Z, Stevenson M, Briggs SS, Oupicky D, Barrett LB, Spice R, Kendall M, Berry M, Preece JA, Logan A, Seymour LW. A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids. Nucleic Acids Research. 33: e86. PMID 15914665 DOI: 10.1093/nar/gni085  0.259
2012 Wu Y, Wang S, Farooq SM, Castelvetere MP, Hou Y, Gao JL, Navarro JV, Oupicky D, Sun F, Li C. A chemokine receptor CXCR2 macromolecular complex regulates neutrophil functions in inflammatory diseases. The Journal of Biological Chemistry. 287: 5744-55. PMID 22203670 DOI: 10.1074/Jbc.M111.315762  0.257
2012 Read ML, Bettinger T, Oupicky D. Methods for Studying the Formation of Polycation-DNA Complexes and Properties Useful for Gene Delivery. Methods in Molecular Medicine. 65: 131-48. PMID 21318751 DOI: 10.1385/1-59259-139-6:131  0.255
2017 Sleightholm RL, Neilsen BK, Li J, Steele MM, Singh RK, Hollingsworth MA, Oupicky D. Emerging Roles of the CXCL12/CXCR4 Axis in Pancreatic Cancer Progression and Therapy. Pharmacology & Therapeutics. PMID 28549596 DOI: 10.1016/J.Pharmthera.2017.05.012  0.254
2022 Jogdeo CM, Panja S, Kanvinde S, Kapoor E, Siddhanta K, Oupický D. Advances in Lipid-Based Codelivery Systems for Cancer and Inflammatory Diseases. Advanced Healthcare Materials. e2202400. PMID 36453542 DOI: 10.1002/adhm.202202400  0.253
2019 Wang Y, Ding L, Li Z, Chen G, Sun M, Oupicky D. Treatment of acute lung injury and early- and late-stage pulmonary fibrosis with combination emulsion siRNA polyplexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31644934 DOI: 10.1016/J.Jconrel.2019.10.030  0.249
2010 Blacklock J, Vetter A, Lankenau A, Oupický D, Möhwald H. Tuning the mechanical properties of bioreducible multilayer films for improved cell adhesion and transfection activity. Biomaterials. 31: 7167-74. PMID 20580430 DOI: 10.1016/J.Biomaterials.2010.06.002  0.249
2018 Chen G, Ding L, Wu P, Zhou Y, Sun M, Wang K, Oupický D. Polymeric micelleplexes for improved photothermal endosomal escape and delivery of siRNA Polymers For Advanced Technologies. 29: 2593-2600. DOI: 10.1002/PAT.4372  0.248
2017 Chen G, Wang K, Hu Q, Ding L, Yu F, Zhou Z, Zhou Y, Li J, Sun M, Oupický D. Combining Fluorination and Bioreducibility for Improved siRNA Polyplex Delivery. Acs Applied Materials & Interfaces. PMID 28135066 DOI: 10.1021/acsami.6b14184  0.245
2018 Routhu NK, Xie Y, Dunworth M, Casero RA, Oupicky D, Byrareddy SN. Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication. Molecular Pharmaceutics. PMID 30040423 DOI: 10.1021/Acs.Molpharmaceut.8B00068  0.245
2022 Yu A, Tang S, Ding L, Foley J, Tang W, Jia H, Panja S, Holbert CE, Hang Y, Stewart TM, Smith LM, Sil D, Casero RA, Oupický D. Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers. Biomaterials Advances. 136. PMID 35813988 DOI: 10.1016/j.bioadv.2022.212755  0.244
2010 Blacklock J, Sievers TK, Handa H, You YZ, Oupický D, Mao G, Möhwald H. Cross-linked bioreducible layer-by-layer films for increased cell adhesion and transgene expression. The Journal of Physical Chemistry. B. 114: 5283-91. PMID 20369813 DOI: 10.1021/Jp100486H  0.244
2009 Chen J, Wu C, Oupický D. Bioreducible hyperbranched poly(amido amine)s for gene delivery. Biomacromolecules. 10: 2921-7. PMID 19743843 DOI: 10.1021/bm900724c  0.243
2019 You YZ, Yan JJ, Yu F, Yu ZQ, Oupicky D. Synthesis of Bioreducible Polycations with Controlled Topologies. Methods in Molecular Biology (Clifton, N.J.). 1943: 27-38. PMID 30838607 DOI: 10.1007/978-1-4939-9092-4_2  0.242
2017 Murray-Stewart T, Ferrari E, Xie Y, Yu F, Marton LJ, Oupicky D, Casero RA. Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047. Plos One. 12: e0178102. PMID 28520822 DOI: 10.1371/Journal.Pone.0178102  0.242
2019 Jang HS, Noh MR, Jung EM, Kim WY, Guda C, Foster KW, Oupicky D, Ferrer FA, Padanilam BJ. Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury. Kidney International. PMID 31733829 DOI: 10.1016/J.Kint.2019.08.019  0.241
2000 Read ML, Dash PR, Clark A, Howard KA, Oupicky D, Toncheva V, Alpar HO, Schacht EH, Ulbrich K, Seymour LW. Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 10: 169-77. PMID 10767594 DOI: 10.1016/S0928-0987(00)00069-5  0.238
2017 Sleightholm R, Yang B, Yu F, Xie Y, Oupický D. Chloroquine-Modified Hydroxyethyl Starch as a Polymeric Drug for Cancer Therapy. Biomacromolecules. PMID 28708385 DOI: 10.1021/acs.biomac.7b00023  0.238
2022 Yu A, Tang S, Ding L, Foley J, Tang W, Jia H, Panja S, Holbert CE, Hang Y, Stewart TM, Smith LM, Sil D, Casero RA, Oupický D. Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers. Biomaterials Advances. 136: 212755. PMID 35929290 DOI: 10.1016/j.bioadv.2022.212755  0.238
2014 Li J, Lepadatu AM, Zhu Y, Ciobanu M, Wang Y, Asaftei SC, Oupický D. Examination of structure-activity relationship of viologen-based dendrimers as CXCR4 antagonists and gene carriers. Bioconjugate Chemistry. 25: 907-17. PMID 24821372 DOI: 10.1021/bc500191q  0.235
2019 Flores L, Sleightholm R, Neilsen B, Baine M, Drincic A, Thorell W, Shonka N, Oupicky D, Zhang C. Highly Aggressive and Radiation-Resistant, "Atypical" and Silent Pituitary Corticotrophic Carcinoma: A Case Report and Review of the Literature. Case Reports in Oncology. 12: 139-146. PMID 31043952 DOI: 10.1159/000496019  0.235
2022 Kumari N, Siddhanta K, Panja S, Joshi V, Jogdeo C, Kapoor E, Khan R, Kollala SS, Kumar B, Sil D, Singh AB, Murry DJ, Oupický D. Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action. Pharmaceutical Research. PMID 36271204 DOI: 10.1007/s11095-022-03415-7  0.235
2017 Sun M, Wang K, Oupický D. Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids. Advanced Healthcare Materials. PMID 29227047 DOI: 10.1002/adhm.201701070  0.234
2021 Hang Y, Tang S, Tang W, Větvička D, Zhang C, Xie Y, Yu F, Yu A, Sil D, Li J, Singh RK, Oupický D. Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33774121 DOI: 10.1016/j.jconrel.2021.03.028  0.232
2019 Ullah A, Wang K, Wu P, Oupicky D, Sun M. CXCR4-targeted liposomal mediated co-delivery of pirfenidone and AMD3100 for the treatment of TGFβ-induced HSC-T6 cells activation. International Journal of Nanomedicine. 14: 2927-2944. PMID 31118614 DOI: 10.2147/IJN.S171280  0.229
1999 Wolfert MA, Dash PR, Nazarova O, Oupicky D, Seymour LW, Smart S, Strohalm J, Ulbrich K. Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA. Bioconjugate Chemistry. 10: 993-1004. PMID 10563768 DOI: 10.1021/Bc990025R  0.228
2010 Dong Y, Li J, Wu C, Oupický D. Bisethylnorspermine lipopolyamine as potential delivery vector for combination drug/gene anticancer therapies. Pharmaceutical Research. 27: 1927-38. PMID 20577786 DOI: 10.1007/s11095-010-0197-4  0.223
2016 Wang Y, Xie Y, Oupický D. Potential of CXCR4/CXCL12 Chemokine Axis in Cancer Drug Delivery. Current Pharmacology Reports. 2: 1-10. PMID 27088072 DOI: 10.1007/s40495-015-0044-8  0.22
2014 Roggers R, Kanvinde S, Boonsith S, Oupický D. The practicality of mesoporous silica nanoparticles as drug delivery devices and progress toward this goal. Aaps Pharmscitech. 15: 1163-71. PMID 24871552 DOI: 10.1208/S12249-014-0142-7  0.22
2014 Wang Y, Li J, Oupický D. Polymeric Plerixafor: effect of PEGylation on CXCR4 antagonism, cancer cell invasion, and DNA transfection. Pharmaceutical Research. 31: 3538-48. PMID 24942536 DOI: 10.1007/s11095-014-1440-1  0.22
2016 Yu F, Xie Y, Sleightholm RL, Li J, Oupický D. Polymeric chloroquine as an inhibitor of cancer cell migration and experimental lung metastasis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27473763 DOI: 10.1016/j.jconrel.2016.07.040  0.217
2012 Li J, Zhu Y, Hazeldine ST, Li C, Oupický D. Dual-function CXCR4 antagonist polyplexes to deliver gene therapy and inhibit cancer cell invasion. Angewandte Chemie (International Ed. in English). 51: 8740-3. PMID 22855422 DOI: 10.1002/Anie.201203463  0.215
2021 Vetvicka D, Sivak L, Jogdeo CM, Kumar R, Khan R, Hang Y, Oupický D. Gene silencing delivery systems for the treatment of pancreatic cancer: Where and what to target next? Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33482273 DOI: 10.1016/j.jconrel.2021.01.020  0.214
2014 Zhu Y, Hazeldine S, Li J, Oupický D. Dendritic polyglycerol with secondary amine shell as an efficient gene delivery vector with reduced toxicity Polymers For Advanced Technologies. 25: 940-947. DOI: 10.1002/pat.3331  0.214
2014 Oupický D, Li J. Bioreducible polycations in nucleic acid delivery: past, present, and future trends. Macromolecular Bioscience. 14: 908-22. PMID 24678057 DOI: 10.1002/mabi.201400061  0.213
2017 Li J, Oupicky D, Ping Q, Sun M. Lysosomal disruptive nanocarrier based on pH-sensitive charge-reversal for tumor targeted anticancer drug delivery Journal of Controlled Release. 259: e66. DOI: 10.1016/j.jconrel.2017.03.152  0.209
2020 Xie Y, Hang Y, Wang Y, Sleightholm R, Prajapati DR, Bader J, Yu A, Tang W, Jaramillo L, Li J, Singh RK, Oupický D. Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy. Acs Nano. PMID 31927946 DOI: 10.1021/acsnano.9b03978  0.207
2013 Li J, Wang Y, Zhu Y, Oupický D. Recent advances in delivery of drug-nucleic acid combinations for cancer treatment. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 589-600. PMID 23624358 DOI: 10.1016/j.jconrel.2013.04.010  0.203
2015 Li J, Yu F, Chen Y, Oupický D. Polymeric drugs: Advances in the development of pharmacologically active polymers. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26410809 DOI: 10.1016/j.jconrel.2015.09.043  0.198
2012 Li J, Zhu Y, Hazeldine ST, Firestine SM, Oupický D. Cyclam-based polymeric copper chelators for gene delivery and potential PET imaging. Biomacromolecules. 13: 3220-7. PMID 23004346 DOI: 10.1021/Bm3009999  0.198
2017 Wang Y, Xie Y, Li J, Peng ZH, Sheinin Y, Zhou J, Oupický D. Tumor-Penetrating Nanoparticles for Enhanced Anticancer Activity of Combined Photodynamic and Hypoxia-Activated Therapy. Acs Nano. PMID 28165223 DOI: 10.1021/acsnano.6b08731  0.197
2010 Shin L, Basi N, Jeremic A, Lee JS, Cho WJ, Chen Z, Abu-Hamdah R, Oupicky D, Jena BP. Involvement of vH(+)-ATPase in synaptic vesicle swelling. Journal of Neuroscience Research. 88: 95-101. PMID 19610106 DOI: 10.1002/Jnr.22180  0.196
2021 Kumar R, Butreddy A, Kommineni N, Reddy PG, Bunekar N, Sarkar C, Dutt S, Mishra VK, Aadil KR, Mishra YK, Oupicky D, Kaushik A. Lignin: Drug/Gene Delivery and Tissue Engineering Applications. International Journal of Nanomedicine. 16: 2419-2441. PMID 33814908 DOI: 10.2147/IJN.S303462  0.195
2016 Yu F, Xie Y, Wang Y, Peng ZH, Li J, Oupický D. Chloroquine-Containing HPMA Copolymers as Polymeric Inhibitors of Cancer Cell Migration Mediated by the CXCR4/SDF-1 Chemokine Axis. Acs Macro Letters. 5: 342-345. PMID 27795873 DOI: 10.1021/acsmacrolett.5b00857  0.193
2018 Xie Y, Wang Y, Li J, Hang Y, Oupický D. Promise of chemokine network-targeted nanoparticles in combination nucleic acid therapies of metastatic cancer. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1528. PMID 29700990 DOI: 10.1002/wnan.1528  0.191
2018 Sun M, Wang K, Oupický D. Therapeutic Nucleic Acids: Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids (Adv. Healthcare Mater. 4/2018) Advanced Healthcare Materials. 7: 1870018. DOI: 10.1002/adhm.201870018  0.191
2020 Wang Y, Xie Y, Kilchrist KV, Li J, Duvall CL, Oupický D. Endosomolytic and Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy. Acs Applied Materials & Interfaces. PMID 31939276 DOI: 10.1021/Acsami.9B21214  0.19
2019 Wang Y, Xie Y, Williams J, Hang Y, Richter L, Becker M, Amador C, Oupický D, Hyde RK. Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia. Cancer Gene Therapy. PMID 31028289 DOI: 10.1038/s41417-019-0095-9  0.19
2015 Wang Y, Li J, Chen Y, Oupický D. Balancing polymer hydrophobicity for ligand presentation and siRNA delivery in dual function CXCR4 inhibiting polyplexes. Biomaterials Science. 3: 1114-1123. PMID 26146552 DOI: 10.1039/C5BM00003C  0.189
2016 Yu F, Xie Y, Wang Y, Peng ZH, Li J, Oupický D. Chloroquine-Containing HPMA Copolymers as Polymeric Inhibitors of Cancer Cell Migration Mediated by the CXCR4/SDF-1 Chemokine Axis Acs Macro Letters. 5: 342-345. DOI: 10.1021/acsmacrolett.5b00857  0.189
2021 Machhi J, Shahjin F, Das S, Patel M, Abdelmoaty MM, Cohen JD, Singh PA, Baldi A, Bajwa N, Kumar R, Vora LK, Patel TA, Oleynikov MD, Soni D, Yeapuri P, ... ... Oupicky D, et al. A Role for Extracellular Vesicles in SARS-CoV-2 Therapeutics and Prevention. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 33544324 DOI: 10.1007/s11481-020-09981-0  0.179
2008 You YZ, Kalebaila KK, Brock SL, Oupický D. Temperature-controlled uptake and release in PNIPAM-modified porous silica nanoparticles Chemistry of Materials. 20: 3354-3359. DOI: 10.1021/Cm703363W  0.177
2022 Sil D, Panja S, Jogdeo CM, Kumar R, Yu A, Holbert CE, Ding L, Foley JR, Stewart TM, Casero RA, Oupický D. Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents. Molecules (Basel, Switzerland). 27. PMID 35458639 DOI: 10.3390/molecules27082441  0.174
2003 Oupický D, Diwadkar V. Stimuli-responsive gene delivery vectors. Current Opinion in Molecular Therapeutics. 5: 345-50. PMID 14513676  0.173
2022 Ding L, Tang S, Yu A, Wang A, Tang W, Jia H, Oupický D. Nanoemulsion-Assisted siRNA Delivery to Modulate the Nervous Tumor Microenvironment in the Treatment of Pancreatic Cancer. Acs Applied Materials & Interfaces. 14: 10015-10029. PMID 35188730 DOI: 10.1021/acsami.1c21997  0.171
2020 Ding L, Tang S, Wyatt TA, Knoell DL, Oupický D. Pulmonary siRNA delivery for lung disease: Review of recent progress and challenges. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33181203 DOI: 10.1016/j.jconrel.2020.11.005  0.171
2018 Xie Y, Wang Y, Li J, Hang Y, Jaramillo L, Wehrkamp CJ, Phillippi MA, Mohr AM, Chen Y, Talmon GA, Mott JL, Oupický D. Cholangiocarcinoma therapy with nanoparticles that combine downregulation of MicroRNA-210 with inhibition of cancer cell invasiveness. Theranostics. 8: 4305-4320. PMID 30214622 DOI: 10.7150/Thno.26506  0.17
2014 Li J, Oupický D. Effect of biodegradability on CXCR4 antagonism, transfection efficacy and antimetastatic activity of polymeric Plerixafor. Biomaterials. 35: 5572-9. PMID 24726746 DOI: 10.1016/j.biomaterials.2014.03.047  0.168
2021 Tang S, Hang Y, Ding L, Tang W, Yu A, Zhang C, Sil D, Xie Y, Oupický D. Intraperitoneal siRNA Nanoparticles for Augmentation of Gemcitabine Efficacy in the Treatment of Pancreatic Cancer. Molecular Pharmaceutics. PMID 34699242 DOI: 10.1021/acs.molpharmaceut.1c00653  0.167
2007 You YZ, Zhou QH, Manickam DS, Wan L, Mao GZ, Oupický D. Dually responsive multiblock copolymers via RAFT polymerization: Synthesis of temperature- and redox-responsive copolymers of PNIPAM and PDMAEMA. Macromolecules. 40: 8617-8624. PMID 18779877 DOI: 10.1021/Ma071176P  0.164
2022 Tang W, Panja S, Jogdeo CM, Tang S, Yu A, Oupický D. Study of Renal Accumulation of Targeted Polycations in Acute Kidney Injury. Biomacromolecules. PMID 35394757 DOI: 10.1021/acs.biomac.2c00079  0.163
2022 Tang S, Kapoor E, Ding L, Yu A, Tang W, Hang Y, Smith LM, Sil D, Oupický D. Effect of tocopherol conjugation on polycation-mediated siRNA delivery to orthotopic pancreatic tumors. Biomaterials Advances. 145: 213236. PMID 36512927 DOI: 10.1016/j.bioadv.2022.213236  0.162
2015 Wang Y, Hazeldine ST, Li J, Oupický D. Development of functional poly(amido amine) CXCR4 antagonists with the ability to mobilize leukocytes and deliver nucleic acids. Advanced Healthcare Materials. 4: 729-38. PMID 25491178 DOI: 10.1002/adhm.201400608  0.161
2019 Wang Y, Xie Y, Li J, Peng ZH, Sheinin Y, Zhou J, Oupický D. Correction to Tumor-Penetrating Nanoparticles for Enhanced Anticancer Activity of Combined Photodynamic and Hypoxia-Activated Therapy. Acs Nano. PMID 30888139 DOI: 10.1021/acsnano.9b01888  0.161
2016 Chen G, Wang K, Zhou Y, Ding L, Ullah A, Hu Q, Sun M, Oupický D. Oral Nanostructured Lipid Carriers Loaded with Near-Infrared Dye for Image-Guided Photothermal Therapy. Acs Applied Materials & Interfaces. PMID 27626389 DOI: 10.1021/acsami.6b07425  0.158
2012 Dong Y, Zhu Y, Li J, Zhou QH, Wu C, Oupický D. Synthesis of bisethylnorspermine lipid prodrug as gene delivery vector targeting polyamine metabolism in breast cancer. Molecular Pharmaceutics. 9: 1654-64. PMID 22545813 DOI: 10.1021/mp300001m  0.156
2005 Wan L, Bisht HS, Oupicky D, Mao G. In situ monitoring of phase transition of a temperature and pH responsive copolymer Aiche Annual Meeting, Conference Proceedings. 14384.  0.156
2003 Seymour LW, Fisher KD, Green NK, Hale SJ, Lyons M, Mautner V, Nicum S, Onion D, Oupicky D, Stevenson M, Ulbrich K. Adenovirus retargeting and systemic delivery. Ernst Schering Research Foundation Workshop. 107-14. PMID 12894454 DOI: 10.1007/978-3-662-05352-2_8  0.155
2017 Peng ZH, Xie Y, Wang Y, Li J, Oupický D. Dual-Function Polymeric HPMA Prodrugs for the Delivery of miRNA. Molecular Pharmaceutics. PMID 28134535 DOI: 10.1021/acs.molpharmaceut.6b00999  0.155
2022 Tang W, Panja S, Jogdeo CM, Tang S, Ding L, Yu A, Foster KW, Dsouza DL, Chhonker YS, Jensen-Smith H, Jang HS, Boesen EI, Murry DJ, Padanilam B, Oupický D. Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury. Biomaterials. 285: 121562. PMID 35552115 DOI: 10.1016/j.biomaterials.2022.121562  0.153
2017 Wang K, Chen G, Ullah A, Zhou Y, Ding L, Hu Q, Sun M, Oupický D. Oral delivery of NIR dye for photothermal therapy based on self-assembled hemoglobin nanoparticles Journal of Controlled Release. 259: e73-e74. DOI: 10.1016/j.jconrel.2017.03.165  0.153
2017 Wang K, Chen G, Hu Q, Zhen Y, Li H, Chen J, Di B, Hu Y, Sun M, Oupický D. Self-assembled hemoglobin nanoparticles for improved oral photosensitizer delivery and oral photothermal therapy in vivo. Nanomedicine (London, England). PMID 28440689 DOI: 10.2217/nnm-2016-0411  0.151
2019 Chen Y, Tang W, Yu F, Xie Y, Jaramillo L, Jang HS, Li J, Padanilam BJ, Oupický D. Determinants of preferential renal accumulation of synthetic polymers in acute kidney injury. International Journal of Pharmaceutics. 118555. PMID 31344445 DOI: 10.1016/J.Ijpharm.2019.118555  0.151
2016 Xie Y, Murray-Stewart T, Wang Y, Yu F, Li J, Marton LJ, Casero RA, Oupický D. Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28017891 DOI: 10.1016/j.jconrel.2016.12.017  0.149
2018 Chen G, Wang K, Wu P, Wang Y, Zhou Z, Yin L, Sun M, Oupický D. Development of fluorinated polyplex nanoemulsions for improved small interfering RNA delivery and cancer therapy Nano Research. 11: 3746-3761. DOI: 10.1007/s12274-017-1946-z  0.149
2022 Jia H, Ding L, Yu A, Tang W, Tang S, Zhang C, Oupický D. A boronate-based modular assembly nanosystem to block the undesirable crosstalk between hepatic stellate cells and Kupffer cells. Bioactive Materials. 25: 569-579. PMID 37056257 DOI: 10.1016/j.bioactmat.2022.07.018  0.146
2023 Yu SY, Luan Y, Tang S, Abazarikia A, Dong R, Caffrey TC, Hollingsworth MA, Oupicky D, Kim SY. Uncovering Tumor-Promoting Roles of Activin A in Pancreatic Ductal Adenocarcinoma. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2207010. PMID 37083240 DOI: 10.1002/advs.202207010  0.146
2022 Ding L, Tang S, Tang W, Mosley DD, Yu A, Sil D, Romanova S, Bailey KL, Knoell DL, Wyatt TA, Oupický D. Perfluorocarbon Nanoemulsions Enhance Therapeutic siRNA Delivery in the Treatment of Pulmonary Fibrosis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2103676. PMID 34994102 DOI: 10.1002/advs.202103676  0.143
2021 Kumar R, Aadil KR, Mondal K, Mishra YK, Oupicky D, Ramakrishna S, Kaushik A. Neurodegenerative disorders management: state-of-art and prospects of nano-biotechnology. Critical Reviews in Biotechnology. 1-33. PMID 34823433 DOI: 10.1080/07388551.2021.1993126  0.143
2017 Zhang F, Gong S, Li H, Oupicky D, Sun M. A dual inhibition of tumor growth and metastasis by CXCR-4 targeting based on redox sensitive dextrin nanogel Journal of Controlled Release. 259: e32. DOI: 10.1016/j.jconrel.2017.03.091  0.142
2018 Zhou Y, Yu F, Zhang F, Chen G, Wang K, Sun M, Li J, Oupický D. Cyclam-Modified PEI for Combined VEGF siRNA Silencing and CXCR4 Inhibition To Treat Metastatic Breast Cancer. Biomacromolecules. PMID 29350899 DOI: 10.1021/acs.biomac.7b01487  0.141
2016 Wang Y, Kumar S, Rachagani S, Sajja BR, Xie Y, Hang Y, Jain M, Li J, Boska MD, Batra SK, Oupický D. Polyplex-mediated inhibition of chemokine receptor CXCR4 and chromatin-remodeling enzyme NCOA3 impedes pancreatic cancer progression and metastasis. Biomaterials. 101: 108-120. PMID 27267632 DOI: 10.1016/J.Biomaterials.2016.05.042  0.138
2022 Khan R, Panja S, Ding L, Tang S, Tang W, Kapoor E, Bennett RG, Oupický D. Polymeric Chloroquine as an Effective Antimigration Agent in the Treatment of Pancreatic Cancer. Molecular Pharmaceutics. PMID 36346968 DOI: 10.1021/acs.molpharmaceut.2c00596  0.136
2022 Peng ZH, Jogdeo CM, Li J, Xie Y, Wang Y, Sheinin YM, Kopeček J, Oupický D. Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model. Pharmaceutics. 14. PMID 36015351 DOI: 10.3390/pharmaceutics14081725  0.136
2018 Ling Ding BS, Chenfei Zhu BS, Fei Yu MS, Pengkai Wu MS, Gang Chen MS, Aftab Ullah BS, Wang K, Sun M, Li J, Oupický D. Pulmonary delivery of polyplexes for combined PAI-1 gene silencing and CXCR4 inhibition to treat lung fibrosis. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29777878 DOI: 10.1016/j.nano.2018.05.005  0.134
2017 Xie Y, Yu F, Tang W, Alade BO, Peng ZH, Wang Y, Li J, Oupický D. Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells. Macromolecular Bioscience. PMID 28776937 DOI: 10.1002/mabi.201700194  0.132
2013 Yuan J, Zhang H, Kaur H, Oupicky D, Peng F. Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA- 64Cu copolymer targeting tumor angiogenesis: Tumor localization visualized by positron emission tomography Molecular Imaging. 12. DOI: 10.2310/7290.2012.00038  0.125
2007 You YZ, Oupický D. Synthesis of temperature-responsive heterobifunctional block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide). Biomacromolecules. 8: 98-105. PMID 17206794 DOI: 10.1021/bm060635b  0.123
2022 Holbert CE, Foley JR, Yu A, Murray Stewart T, Phanstiel O, Oupicky D, Casero RA. Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy. Medical Sciences (Basel, Switzerland). 10. PMID 35997336 DOI: 10.3390/medsci10030044  0.121
2021 Tang W, Chen Y, Jang HS, Hang Y, Jogdeo CM, Li J, Ding L, Zhang C, Yu A, Yu F, Foster KW, Padanilam BJ, Oupický D. Preferential siRNA delivery to injured kidneys for combination treatment of acute kidney injury. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34826532 DOI: 10.1016/j.jconrel.2021.11.029  0.108
2018 Kanvinde S, Chhonker YS, Ahmad R, Yu F, Sleightholm R, Tang W, Jaramillo L, Chen Y, Sheinin Y, Li J, Murry DJ, Singh AB, Oupický D. Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease. Acta Biomaterialia. PMID 30342282 DOI: 10.1016/j.actbio.2018.10.027  0.107
2017 Li J, Zhang C, He W, Qiao H, Chen J, Wang K, Oupický D, Sun M. Coordination-driven assembly of catechol-modified chitosan for the kidney-specific delivery of salvianolic acid B to treat renal fibrosis. Biomaterials Science. PMID 29170782 DOI: 10.1039/c7bm00811b  0.105
2013 Wu C, Li J, Zhu Y, Chen J, Oupický D. Opposing influence of intracellular and membrane thiols on the toxicity of reducible polycations. Biomaterials. 34: 8843-50. PMID 23948163 DOI: 10.1016/j.biomaterials.2013.07.095  0.102
2021 Kumar B, Ahmad R, Sharma S, Gowrikumar S, Primeaux M, Rana S, Natarajan A, Oupicky D, Hopkins CR, Dhawan P, Singh AB. PIK3C3 Inhibition Promotes Sensitivity to Colon Cancer Therapy by Inhibiting Cancer Stem Cells. Cancers. 13. PMID 33946505 DOI: 10.3390/cancers13092168  0.093
2021 Machhi J, Shahjin F, Das S, Patel M, Abdelmoaty MM, Cohen JD, Singh PA, Baldi A, Bajwa N, Kumar R, Vora LK, Patel TA, Oleynikov MD, Soni D, Yeapuri P, ... ... Oupicky D, et al. Nanocarrier Vaccines for SARS-CoV-2. Advanced Drug Delivery Reviews. PMID 33428995 DOI: 10.1016/j.addr.2021.01.002  0.092
2022 Zhang C, Hang Y, Tang W, Sil D, Jensen-Smith HC, Bennett RG, McVicker BL, Oupický D. Dually Active Polycation/miRNA Nanoparticles for the Treatment of Fibrosis in Alcohol-Associated Liver Disease. Pharmaceutics. 14. PMID 35336043 DOI: 10.3390/pharmaceutics14030669  0.091
2017 Ullah A, Wang K, Chen G, Zhou Y, Ding L, Hu Q, Oupický D. CXCR4-targeted combination therapy for the treatment of liver fibrosis Journal of Controlled Release. 259: e5-e6. DOI: 10.1016/j.jconrel.2017.03.044  0.082
2000 Konâk C, Oupicky D, Chytry V, Ulbrich K, Helmstedt M. Thermally controlled association in aqueous solutions of diblock copolymers of poly[Ar-(2-hydroxypropyl)methacrylamide] and polyCW-isopropylacrylamide Macromolecules. 33: 5318-5320.  0.076
2021 Chhonker YS, Kanvinde S, Ahmad R, Singh AB, Oupický D, Murry DJ. Simultaneous Quantitation of Lipid Biomarkers for Inflammatory Bowel Disease Using LC-MS/MS. Metabolites. 11. PMID 33673198 DOI: 10.3390/metabo11020106  0.075
2018 Chhonker YS, Sleightholm RL, Li J, Oupický D, Murry DJ. Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC-ESI-MS/MS: An application for pharmacokinetic studies. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1072: 320-327. PMID 29207305 DOI: 10.1016/j.jchromb.2017.11.026  0.074
2016 Xie Y, Wehrkamp CJ, Li J, Wang Y, Wang Y, Mott JL, Oupický D. Delivery of miR-200c Mimic with Poly(amido amine) CXCR4 Antagonists for Combined Inhibition of Cholangiocarcinoma Cell Invasiveness. Molecular Pharmaceutics. PMID 26855082 DOI: 10.1021/Acs.Molpharmaceut.5B00894  0.072
2017 Chen G, Wang K, Ullah A, Zhou Y, Ding L, Hu Q, Sun M, Oupický D. Self-assembled fluoropolycation nanomicelles for improved siRNA silencing Journal of Controlled Release. 259: e35-e36. DOI: 10.1016/j.jconrel.2017.03.097  0.071
2019 Baine MJ, Sleightholm R, Neilsen BK, Oupický D, Smith LM, Verma V, Lin C. Stereotactic Body Radiation Therapy Versus Nonradiotherapeutic Ablative Procedures (Laser/Cryoablation and Electrocautery) for Early-Stage Non-Small Cell Lung Cancer. Journal of the National Comprehensive Cancer Network : Jnccn. 17: 450-458. PMID 31085762 DOI: 10.6004/Jnccn.2018.7269  0.069
2013 Ogris M, Oupicky D. Preface Methods in Molecular Biology. 948.  0.01
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