Hongwu Chen - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Molecular Biology, Oncology

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kong X, Yan W, Sun W, Zhang Y, Yang HJ, Chen M, Chen H, de Vere White RW, Zhang J, Chen X. Isoform-specific disruption of the gene reveals a critical role for TAp73γ in tumorigenesis via leptin. Elife. 12. PMID 37650871 DOI: 10.7554/eLife.82115  0.326
2023 Zou H, Yang Y, Chen HW. Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner. Frontiers in Pharmacology. 14: 1146741. PMID 37180705 DOI: 10.3389/fphar.2023.1146741  0.399
2022 Ning S, Zhao J, Lombard AP, D'Abronzo LS, Leslie AR, Sharifi M, Lou W, Liu C, Yang JC, Evans CP, Corey E, Chen HW, Yu A, Ghosh PM, Gao AC. Activation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes. Communications Medicine. 2: 118. PMID 36159187 DOI: 10.1038/s43856-022-00182-9  0.304
2022 Yang N, Yang Y, Huang Z, Chen HW. Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer. Cancers. 14. PMID 35804882 DOI: 10.3390/cancers14133110  0.302
2022 Zou H, Yang Y, Shi Z, Wu X, Liu R, Yu AM, Chen HW. Nuclear receptor RORγ inverse agonists/antagonists display tissue- and gene-context selectivity through distinct activities in altering chromatin accessibility and master regulator SREBP2 occupancy. Pharmacological Research. 182: 106324. PMID 35750301 DOI: 10.1016/j.phrs.2022.106324  0.301
2021 Wang H, Wang Q, Cai G, Duan Z, Nugent Z, Huang J, Zheng J, Borowsky AD, Li JJ, Liu P, Kung HJ, Murphy L, Chen HW, Wang J. Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop NRF2 in cancer therapeutic resistance. Acta Pharmaceutica Sinica. B. 12: 1871-1884. PMID 35847493 DOI: 10.1016/j.apsb.2021.10.015  0.339
2021 Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, Li CF, Wang LH, Chen HW, Yen Y, Ann DK, et al. Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes. Theranostics. 11: 7527-7545. PMID 34158865 DOI: 10.7150/thno.54695  0.309
2021 Zhang X, Huang Z, Wang J, Ma Z, Yang J, Corey E, Evans CP, Yu AM, Chen HW. Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling. Cancers. 13. PMID 33916325 DOI: 10.3390/cancers13071672  0.371
2020 Zheng J, Wang J, Wang Q, Zou H, Wang H, Zhang Z, Chen J, Wang Q, Wang P, Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, ... Chen HW, et al. Targeting castration-resistant prostate cancer with a novel ROR antagonist elaiophylin. Acta Pharmaceutica Sinica. B. 10: 2313-2322. PMID 33354503 DOI: 10.1016/J.Apsb.2020.07.001  0.483
2020 Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, ... ... Chen HW, et al. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nature Communications. 11: 4591. PMID 32929084 DOI: 10.1038/S41467-020-18245-7  0.382
2020 Wang Q, Zheng J, Zou JX, Xu J, Han F, Xiang S, Liu P, Chen HW, Wang J. S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis. Chemico-Biological Interactions. 108965. PMID 32001260 DOI: 10.1016/j.cbi.2020.108965  0.318
2019 Duan Z, Andrews NP, Chen CZ, Fan M, Wang J, Shen J, Li JJ, Chen HW. Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation. Oncology Reports. PMID 31789405 DOI: 10.3892/Or.2019.7418  0.367
2019 Wang Y, Huang Z, Chen CZ, Liu C, Evans CP, Gao AC, Zhou F, Chen HW. Therapeutic targeting MDR1 expression by RORγ antagonists resensitizes cross-resistant CRPC to taxane via coordinated induction of cell death programs. Molecular Cancer Therapeutics. PMID 31712394 DOI: 10.1158/1535-7163.MCT-19-0327  0.311
2019 Lombard AP, Liu C, Armstrong CM, D'Abronzo LS, Lou W, Chen H, Dall'Era M, Ghosh PM, Evans CP, Gao AC. Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer. Translational Oncology. 12: 871-878. PMID 31075528 DOI: 10.1016/J.Tranon.2019.04.007  0.361
2019 Zhang Y, Wu X, Xue X, Li C, Wang J, Wang R, Zhang C, Wang C, Shi Y, Zou L, Li Q, Huang Z, Hao X, Loomes KM, Wu D, ... Chen H, et al. Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer (CRPC). Journal of Medicinal Chemistry. PMID 30964293 DOI: 10.1021/Acs.Jmedchem.9B00327  0.431
2019 Wang JJ, Zou JX, Wang H, Duan ZJ, Wang HB, Chen P, Liu PQ, Xu JZ, Chen HW. Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling. Acta Pharmacologica Sinica. PMID 30670815 DOI: 10.1038/S41401-018-0199-Z  0.436
2019 Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel OD, Tepper CG, Chen H, Dall’Era M, Evans CP, Gao AC. Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone Cancer Research. 79: 334-334. DOI: 10.1158/1538-7445.Am2019-334  0.456
2019 Liu* C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel OD, Tepper CG, Dall’Era M, Chen H, Evans CP, Gao AC. MP22-08 PROTEOSTASIS BY HSP70/STUB1 COMPLEX REGULATES ANDROGEN RECEPTOR VARIANTS EXPRESSION AND CONFERS RESISTANCE TO ENZALUTAMIDE AND ABIRATERONE Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555593.31745.C3  0.438
2018 Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel ODV, Tepper CG, Chen HW, Dall'Era M, Evans CP, Gao AC. Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer. Nature Communications. 9: 4700. PMID 30446660 DOI: 10.1038/S41467-018-07178-X  0.425
2018 Wang HJ, Pochampalli M, Wang LY, Zou JX, Li PS, Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, ... ... Chen HW, et al. KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene. PMID 30072740 DOI: 10.1038/S41388-018-0414-X  0.375
2018 Xue X, Zhang Y, Wang C, Zhang M, Xiang Q, Wang J, Wang A, Li C, Zhang C, Zou L, Wang R, Wu S, Lu Y, Chen H, Ding K, et al. Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer. European Journal of Medicinal Chemistry. 152: 542-559. PMID 29758518 DOI: 10.1016/J.Ejmech.2018.04.034  0.408
2018 Zhang M, Zhang Y, Song M, Xue X, Wang J, Wang C, Zhang C, Li C, Xiang Q, Zou L, Wu X, Wu C, Dong B, Xue W, Zhou Y, ... Chen H, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). Journal of Medicinal Chemistry. PMID 29566488 DOI: 10.1021/Acs.Jmedchem.8B00103  0.372
2017 Candas D, Zhang L, Menaa C, Fan M, Zhang Y, Liu L, Zhou W, Azghadi S, Sweeney C, Shen R, Lin T, Pan C, Vaughan AT, Wang JM, Chen H, et al. Abstract LB-226: Dual inhibition of CD47 and HER2 to radiosensitize breast cancer cells Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-226  0.355
2016 Wang J, Wang H, Wang LY, Cai D, Duan Z, Zhang Y, Chen P, Zou JX, Xu J, Chen X, Kung HJ, Chen HW. Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy. Cell Death and Differentiation. PMID 27612013 DOI: 10.1038/Cdd.2016.92  0.336
2016 Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, ... ... Chen HW, et al. Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. 22: 692. PMID 27270780 DOI: 10.1038/Nm0616-692B  0.67
2016 Chen P, Wang H, Yang F, Chen H, He W, Wang J. Curcumin Promotes Osteosarcoma Cell Death by Activating miR-125a/ERRα Signal Pathway. Journal of Cellular Biochemistry. PMID 27231954 DOI: 10.1002/Jcb.25612  0.369
2016 Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, ... ... Chen HW, et al. ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. PMID 27019329 DOI: 10.1038/Nm.4070  0.684
2016 Wang J, Wang H, Wang L, Cai D, Duan Z, Chen P, Zou JX, Xu J, Chen X, Kung H, Chen H. Abstract 3062: Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy Cancer Research. 76: 3062-3062. DOI: 10.1158/1538-7445.Am2016-3062  0.449
2015 Krakstad C, Tangen IL, Hoivik EA, Halle MK, Berg A, Werner HM, Ræder MB, Kusonmano K, Zou JX, Øyan AM, Stefansson I, Trovik J, Kalland KH, Chen HW, Salvesen HB. ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma. Oncotarget. 6: 28440-52. PMID 26308378 DOI: 10.18632/Oncotarget.4955  0.387
2015 Wang Y, Stokes A, Duan Z, Hui J, Xu Y, Chen Y, Chen HW, Lam K, Zhou CJ. LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia. Journal of the American Society of Nephrology : Jasn. PMID 26047795 DOI: 10.1681/Asn.2014100998  0.306
2015 Huang X, Zhang S, Qi H, Wang Z, Chen HW, Shao J, Shen J. JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation. Biochimica Et Biophysica Acta. PMID 26025680 DOI: 10.1016/J.Bbamcr.2015.05.026  0.419
2015 Wang L, Hung C, Yu Y, Chen H, Srivastava S, Petrovics G, Kung H. Abstract B16: A novel long non-coding RNA connects c-Myc to tumor metabolism Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B16  0.43
2014 Hung CL, Wang LY, Yu YL, Chen HW, Srivastava S, Petrovics G, Kung HJ. A long noncoding RNA connects c-Myc to tumor metabolism. Proceedings of the National Academy of Sciences of the United States of America. 111: 18697-702. PMID 25512540 DOI: 10.1073/pnas.1415669112  0.329
2014 Chen P, Wang H, Duan Z, Zou JX, Chen H, He W, Wang J. Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. Biomed Research International. 2014: 616025. PMID 24967384 DOI: 10.1155/2014/616025  0.374
2014 Zou JX, Duan Z, Wang J, Sokolov A, Xu J, Chen CZ, Li JJ, Chen HW. Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance. Molecular Cancer Research : McR. 12: 539-49. PMID 24391143 DOI: 10.1158/1541-7786.Mcr-13-0459  0.479
2014 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ. Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells (Dayton, Ohio). 32: 45-58. PMID 24115331 DOI: 10.1002/Stem.1561  0.303
2014 Krakstad C, Tangen IL, Raeder MB, Hoivik E, Kusonmano K, Zou JX, Øyan AM, Trovik J, Chen H, Kalland KH, Salvesen HB. Abstract 2875: ATAD2 overexpression indentifies aggressive endometrial carcinomas Cancer Research. 74: 2875-2875. DOI: 10.1158/1538-7445.Am2014-2875  0.378
2014 Zou JX, Wang J, Duan Z, Chen H, Kung H, Chen X, Murphy LC, Borowsky A. Abstract 2433: Metabolic reprogramming by an epigenetic mechanism in endocrine therapy resistance of breast cancer Cancer Research. 74: 2433-2433. DOI: 10.1158/1538-7445.Am2014-2433  0.429
2013 Tummala R, Nadiminty N, Lou W, Zhu Y, Gandour-Edwards R, Chen HW, Evans CP, Gao AC. Lin28 promotes growth of prostate cancer cells and activates the androgen receptor. The American Journal of Pathology. 183: 288-95. PMID 23790802 DOI: 10.1016/J.Ajpath.2013.03.011  0.469
2013 Chen NT, Kuwabara Y, Conley C, Liao YC, Hong SY, Chen M, Shih YP, Chen HW, Hsieh F, Lo SH. Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene. Gene. 520: 90-7. PMID 23500447 DOI: 10.1016/J.Gene.2013.02.041  0.391
2013 Duan Z, Zou JX, Yang P, Wang Y, Borowsky AD, Gao AC, Chen HW. Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex. The Prostate. 73: 455-66. PMID 23038103 DOI: 10.1002/Pros.22587  0.404
2012 Berger CE, Qian Y, Liu G, Chen H, Chen X. p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells. The Journal of Biological Chemistry. 287: 30117-27. PMID 22787161 DOI: 10.1074/Jbc.M112.367326  0.417
2012 Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X, Kung HJ, Gao AC, Zou JX, Chen HW. Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Molecular and Cellular Biology. 32: 3121-31. PMID 22645312 DOI: 10.1128/Mcb.00204-12  0.411
2012 Nadiminty N, Tummala R, Lou W, Zhu Y, Shi XB, Zou JX, Chen H, Zhang J, Chen X, Luo J, deVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. Plos One. 7: e32832. PMID 22479342 DOI: 10.1371/Journal.Pone.0032832  0.395
2011 Zhang J, Cho SJ, Shu L, Yan W, Guerrero T, Kent M, Skorupski K, Chen H, Chen X. Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes & Development. 25: 1528-43. PMID 21764855 DOI: 10.1101/Gad.2069311  0.307
2010 Hsia EY, Goodson ML, Zou JX, Privalsky ML, Chen HW. Nuclear receptor coregulators as a new paradigm for therapeutic targeting. Advanced Drug Delivery Reviews. 62: 1227-37. PMID 20933027 DOI: 10.1016/J.Addr.2010.09.016  0.384
2010 Kalashnikova EV, Revenko AS, Gemo AT, Andrews NP, Tepper CG, Zou JX, Cardiff RD, Borowsky AD, Chen HW. ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2. Cancer Research. 70: 9402-12. PMID 20864510 DOI: 10.1158/0008-5472.Can-10-1199  0.651
2010 Revenko AS, Kalashnikova EV, Gemo AT, Zou JX, Chen HW. Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Molecular and Cellular Biology. 30: 5260-72. PMID 20855524 DOI: 10.1128/Mcb.00484-10  0.664
2010 Hsia EY, Kalashnikova EV, Revenko AS, Zou JX, Borowsky AD, Chen HW. Deregulated E2F and the AAA+ coregulator ANCCA drive proto-oncogene ACTR/AIB1 overexpression in breast cancer. Molecular Cancer Research : McR. 8: 183-93. PMID 20124470 DOI: 10.1158/1541-7786.Mcr-09-0095  0.65
2009 Hsia EYC, Zou JX, Chen HW. Chapter 8 The Roles and Action Mechanisms of p160/SRC Coactivators and the ANCCA Coregulator in Cancer Progress in Molecular Biology and Translational Science. 87: 261-298. PMID 20374707 DOI: 10.1016/S1877-1173(09)87008-7  0.49
2009 Qin L, Liu Z, Chen H, Xu J. The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Research. 69: 3819-27. PMID 19383905 DOI: 10.1158/0008-5472.Can-08-4389  0.454
2009 Zou JX, Guo L, Revenko AS, Tepper CG, Gemo AT, Kung HJ, Chen HW. Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Research. 69: 3339-46. PMID 19318566 DOI: 10.1158/0008-5472.CAN-08-3440  0.387
2008 Shi XB, Xue L, Zou JX, Gandour-Edwards R, Chen H, deVere White RW. Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells. The Prostate. 68: 1816-26. PMID 18780293 DOI: 10.1002/Pros.20849  0.443
2008 Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and Cellular Biology. 28: 5937-50. PMID 18644862 DOI: 10.1128/Mcb.00579-08  0.364
2008 Li LB, Louie MC, Chen HW, Zou JX. Proto-oncogene ACTR/AIB1 promotes cancer cell invasion by up-regulating specific matrix metalloproteinase expression. Cancer Letters. 261: 64-73. PMID 18162290 DOI: 10.1016/J.Canlet.2007.11.013  0.661
2007 Zou JX, Revenko AS, Li LB, Gemo AT, Chen HW. ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification. Proceedings of the National Academy of Sciences of the United States of America. 104: 18067-72. PMID 17998543 DOI: 10.1073/Pnas.0705814104  0.445
2006 Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ. Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Research. 66: 10449-59. PMID 17079466 DOI: 10.1158/0008-5472.Can-06-2582  0.31
2006 Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ. Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Cancer Research. 66: 8439-47. PMID 16951154 DOI: 10.1158/0008-5472.Can-06-1636  0.445
2006 Zou JX, Zhong Z, Shi XB, Tepper CG, deVere White RW, Kung HJ, Chen H. ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes. The Prostate. 66: 1474-86. PMID 16921507 DOI: 10.1002/Pros.20477  0.499
2006 Louie MC, Revenko AS, Zou JX, Yao J, Chen HW. Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity. Molecular and Cellular Biology. 26: 3810-23. PMID 16648476 DOI: 10.1128/Mcb.26.10.3810-3823.2006  0.698
2004 Louie MC, Zou JX, Rabinovich A, Chen HW. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Molecular and Cellular Biology. 24: 5157-71. PMID 15169882 DOI: 10.1128/Mcb.24.12.5157-5171.2004  0.713
2004 Lee LF, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, Kung HJ. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene. 23: 2197-205. PMID 14767470 DOI: 10.1038/Sj.Onc.1207344  0.648
2003 Louie MC, Yang HQ, Ma AH, Xu W, Zou JX, Kung HJ, Chen HW. Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex. Proceedings of the National Academy of Sciences of the United States of America. 100: 2226-30. PMID 12589022 DOI: 10.1073/Pnas.0437824100  0.652
2002 Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature. 415: 549-53. PMID 11823864 DOI: 10.1038/415549A  0.41
2001 Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961  0.318
2001 Chen H, Tini M, Evans RM. HATs on and beyond chromatin. Current Opinion in Cell Biology. 13: 218-24. PMID 11248556 DOI: 10.1016/S0955-0674(00)00200-3  0.313
1999 Chen H, Lin RJ, Xie W, Wilpitz D, Evans RM. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell. 98: 675-86. PMID 10490106 DOI: 10.1016/S0092-8674(00)80054-9  0.39
1999 Chakravarti D, Ogryzko V, Kao HY, Nash A, Chen H, Nakatani Y, Evans RM. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell. 96: 393-403. PMID 10025405 DOI: 10.1016/S0092-8674(00)80552-8  0.339
1998 Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, Evans RM, Nakatani Y, Ozato K. The histone acetylase PCAF is a nuclear receptor coactivator. Genes & Development. 12: 1638-51. PMID 9620851 DOI: 10.1101/Gad.12.11.1638  0.374
1998 Blumberg B, Kang H, Bolado J, Chen H, Craig AG, Moreno TA, Umesono K, Perlmann T, De Robertis EM, Evans RM. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes & Development. 12: 1269-77. PMID 9573044 DOI: 10.1101/Gad.12.9.1269  0.337
1998 Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93: 229-40. PMID 9568715 DOI: 10.1016/S0092-8674(00)81574-3  0.345
1997 Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4  0.371
1997 Chen HW, Privalsky ML. Retinoid X and retinoic acid receptors interact with transcription factor II-B by distinct mechanisms Molecular and Cellular Endocrinology. 129: 55-61. PMID 9175629 DOI: 10.1016/S0303-7207(97)04040-9  0.371
1997 Lin BC, Wong CW, Chen HW, Privalsky ML. Plasticity of tetramer formation by retinoid X receptors. An alternative paradigm for DNA recognition. The Journal of Biological Chemistry. 272: 9860-7. PMID 9092522 DOI: 10.1074/Jbc.272.15.9860  0.331
1995 Chen H, Privalsky ML. Cooperative formation of high-order oligomers by retinoid X receptors: An unexpected mode of DNA recognition Proceedings of the National Academy of Sciences of the United States of America. 92: 422-426. PMID 7831303 DOI: 10.1073/Pnas.92.2.422  0.373
1993 Chen HW, Privalsky ML. The erbA oncogene represses the actions of both retinoid X and retinoid A receptors but does so by distinct mechanisms Molecular and Cellular Biology. 13: 5970-5980. PMID 8105369 DOI: 10.1128/Mcb.13.10.5970  0.372
1993 Chen H, Smit-Mcbride Z, Lewis S, Sharif M, Privalsky ML. Nuclear hormone receptors involved in neoplasia: Erb A exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domain Molecular and Cellular Biology. 13: 2366-2376. PMID 8096060 DOI: 10.1128/Mcb.13.4.2366  0.37
1993 Sande S, Sharif M, Chen H, Privalsky M. v-erbA acts on retinoic acid receptors in immature avian erythroid cells. Journal of Virology. 67: 1067-74. PMID 8093487 DOI: 10.1128/Jvi.67.2.1067-1074.1993  0.377
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