Keiko Ozato - Publications

Affiliations: 
University of Maryland, College Park, College Park, MD 
Area:
Molecular Biology, Genetics, Biochemistry

290 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kurotaki D, Kikuchi K, Cui K, Kawase W, Saeki K, Fukumoto J, Nishiyama A, Nagamune K, Zhao K, Ozato K, Rocha PP, Tamura T. Chromatin structure undergoes global and local reorganization during murine dendritic cell development and activation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207009119. PMID 35969760 DOI: 10.1073/pnas.2207009119  0.324
2021 Murakami K, Sasaki H, Nishiyama A, Kurotaki D, Kawase W, Ban T, Nakabayashi J, Kanzaki S, Sekita Y, Nakajima H, Ozato K, Kimura T, Tamura T. A RUNX-CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes. Nature Immunology. PMID 33603226 DOI: 10.1038/s41590-021-00871-y  0.313
2020 Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, Osako F, Kobayashi M, Nishiyama A, Kataoka Y, Takai T, Udagawa N, Jung S, Ozato K, Tamura T, et al. Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction. The Embo Journal. e104464. PMID 32959911 DOI: 10.15252/Embj.2020104464  0.34
2020 Das A, Wang X, Kang J, Coulter A, Shetty AC, Bachu M, Brooks SR, Dell'Orso S, Foster BL, Fan X, Ozato K, Somerman MJ, Thumbigere-Math V. Monocyte Subsets with High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32804442 DOI: 10.1002/Jbmr.4165  0.429
2020 Kunishita Y, Yoshimi R, Kamiyama R, Kishimoto D, Yoshida K, Hashimoto E, Komiya T, Sakurai N, Sugiyama Y, Kirino Y, Ozato K, Nakajima H. TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis. Frontiers in Immunology. 11: 98. PMID 32117252 DOI: 10.3389/Fimmu.2020.00098  0.322
2020 Chen C, Sun MA, Warzecha C, Bachu M, Dey A, Wu T, Adams PD, Macfarlan T, Love P, Ozato K. HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis. Cell Reports. PMID 32075733 DOI: 10.1016/J.Celrep.2020.01.062  0.396
2019 Inoue T, Hariya N, Imamochi Y, Dey A, Ozato K, Goda T, Kubota T, Mochizuki K. Epigenetic regulation of lipoprotein lipase gene via BRD4, which is potentially associated with adipocyte differentiation and insulin resistance. European Journal of Pharmacology. 858: 172492. PMID 31233750 DOI: 10.1016/J.Ejphar.2019.172492  0.384
2019 Panda D, Gjinaj E, Bachu M, Squire E, Novatt H, Ozato K, Rabin RL. IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response. Frontiers in Immunology. 10: 1019. PMID 31156620 DOI: 10.3389/Fimmu.2019.01019  0.423
2019 Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, Grinberg A, Finkelman FD, Pfeifer K, Zhu J, Singer D, Zhu J, Ozato K. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. The Embo Journal. PMID 30842097 DOI: 10.15252/Embj.2018100293  0.373
2019 Thumbigere-Math V, Foster BL, Bachu M, Yoshii H, Brooks SR, Coulter A, Chavez MB, Togi S, Neely AL, Deng Z, Mansky KC, Ozato K, Somerman MJ. Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30840779 DOI: 10.1002/Jbmr.3690  0.388
2019 Kurotaki D, Kawase W, Sasaki H, Nakabayashi J, Nishiyama A, Morse HC, Ozato K, Suzuki Y, Tamura T. Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice. Blood. PMID 30796024 DOI: 10.1182/Blood-2018-06-857789  0.414
2019 Klement JD, Paschall AV, Redd PS, Ibrahim ML, Lu C, Yang D, Celis E, Abrams SI, Ozato K, Liu K. Abstract 3226: The IRF8-osteopontin-CD44 axis functions as an immune checkpoint to control CD8+ T cell activation and tumor immune evasion Cancer Research. 79: 3226-3226. DOI: 10.1158/1538-7445.Am2019-3226  0.36
2019 Kawase W, Kurotaki D, Sasaki H, Nakabayashi J, Nishiyama A, Morse H, Ozato K, Suzuki Y, Tamura T. The Transcription Factor Irf8 Epigenetically Regulates Early Dendritic Cell Specification Experimental Hematology. 76. DOI: 10.1016/J.Exphem.2019.06.374  0.415
2018 Bachu M, Tamura T, Chen C, Narain A, Nehru V, Sarai N, Ghosh SB, Ghosh A, Kavarthapu R, Dufau ML, Ozato K. A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics. The Journal of Biological Chemistry. PMID 30552116 DOI: 10.1074/Jbc.Ra118.005550  0.398
2018 Klement JD, Paschall AV, Redd PS, Ibrahim ML, Lu C, Yang D, Celis E, Abrams SI, Ozato K, Liu K. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. The Journal of Clinical Investigation. PMID 30395540 DOI: 10.1172/Jci123360  0.368
2018 Zhang R, Qi CF, Hu Y, Shan Y, Hsieh YP, Xu F, Lu G, Dai J, Gupta M, Cui M, Peng L, Yang J, Xue Q, Chen-Liang R, Chen K, ... ... Ozato K, et al. T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation. Journal of Autoimmunity. PMID 30241692 DOI: 10.1016/J.Jaut.2018.09.001  0.307
2018 Kamada R, Yang W, Zhang Y, Patel MC, Yang Y, Ouda R, Dey A, Wakabayashi Y, Sakaguchi K, Fujita T, Tamura T, Zhu J, Ozato K. Interferon stimulation creates chromatin marks and establishes transcriptional memory. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201712 DOI: 10.1073/Pnas.1720930115  0.309
2018 Gegonne A, Chen QR, Dey A, Etzensperger R, Tai X, Singer A, Meerzaman D, Ozato K, Singer DS. Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation. Cell Reports. 24: 117-129. PMID 29972774 DOI: 10.1016/J.Celrep.2018.06.007  0.34
2018 Ouda R, Sarai N, Nehru V, Patel MC, Debrosse M, Bachu M, Chereji RV, Eriksson PR, Clark DJ, Ozato K. SPT6 interacts with NSD2 and facilitates interferon-induced transcription. Febs Letters. PMID 29683485 DOI: 10.1002/1873-3468.13069  0.452
2018 Haque N, Ouda R, Chen C, Ozato K, Hogg JR. ZFR coordinates crosstalk between RNA decay and transcription in innate immunity. Nature Communications. 9: 1145. PMID 29559679 DOI: 10.1038/S41467-018-03326-5  0.414
2018 Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kawase W, Kaneko N, Ochiai K, Igarashi K, Ozato K, Suzuki Y, Tamura T. Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors. Cell Reports. 22: 2628-2641. PMID 29514092 DOI: 10.1016/J.Celrep.2018.02.048  0.429
2018 Klement JD, Paschall AV, Zimmerman MA, Ibrahim ML, Redd PS, Lu C, Sultan H, Celis E, Ozato K, Liu K. Abstract 4682: IRF8 controls T cell development and survival to regulate T cell antitumor activity Cancer Research. 78: 4682-4682. DOI: 10.1158/1538-7445.Am2018-4682  0.36
2017 Lee JE, Park YK, Park S, Jang Y, Waring N, Dey A, Ozato K, Lai B, Peng W, Ge K. Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis. Nature Communications. 8: 2217. PMID 29263365 DOI: 10.1038/S41467-017-02403-5  0.447
2017 Yu X, Chen H, Zuo C, Jin X, Yin Y, Wang H, Jin M, Ozato K, Xu S. Chromatin remodeling: demethylating H3K4me3 of type I IFNs gene by Rbp2 through interacting with Piasy for transcriptional attenuation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28970247 DOI: 10.1096/Fj.201700088Rr  0.467
2017 Valanparambil RM, Tam M, Gros PP, Auger JP, Segura M, Gros P, Jardim A, Geary TG, Ozato K, Stevenson MM. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. Plos Pathogens. 13: e1006647. PMID 28968468 DOI: 10.1371/Journal.Ppat.1006647  0.335
2017 Sakurai N, Inamochi Y, Inoue T, Hariya N, Kawamura M, Yamada M, Dey A, Nishiyama A, Kubota T, Ozato K, Goda T, Mochizuki K. BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene. Scientific Reports. 7: 11962. PMID 28931940 DOI: 10.1038/S41598-017-12342-2  0.405
2016 Inamochi Y, Dey A, Nishiyama A, Kubota T, Ozato K, Goda T, Mochizuki K. Transcription elongation factor Brd4-P-TEFb accelerates intestinal differentiation-associated SLC2A5 gene expression. Biochemistry and Biophysics Reports. 7: 150-156. PMID 28955901 DOI: 10.1016/J.Bbrep.2016.05.016  0.401
2016 Mace EM, Bigley V, Gunesch JT, Chinn IK, Angelo LS, Care MA, Maisuria S, Keller MD, Togi S, Watkin LB, LaRosa DF, Jhangiani SN, Muzny DM, Stray-Pedersen A, Coban Akdemir Z, ... ... Ozato K, et al. Biallelic mutations in IRF8 impair human NK cell maturation and function. The Journal of Clinical Investigation. PMID 27893462 DOI: 10.1172/Jci86276  0.34
2016 Miyagawa F, Tagaya Y, Ozato K, Asada H. Essential Requirement for IFN Regulatory Factor 7 in Autoantibody Production but Not Development of Nephritis in Murine Lupus. Journal of Immunology (Baltimore, Md. : 1950). PMID 27527596 DOI: 10.4049/Jimmunol.1502445  0.371
2016 Bachu M, Dey A, Ozato K. Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 36: 470-475. PMID 27379869 DOI: 10.1089/Jir.2015.0179  0.385
2016 Ozato K. Introduction to a Special Issue on IFN Regulatory Factors in Innate Immune Responses. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 36: 413. PMID 27379863 DOI: 10.1089/Jir.2016.29002.Koz  0.314
2016 Huang XF, Nandakumar V, Tumurkhuu G, Wang T, Jiang X, Hong B, Jones L, Won H, Yoshii H, Ozato K, Masumi A, Chen SY. Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development. Cell Death & Disease. 7: e2260. PMID 27277682 DOI: 10.1038/Cddis.2016.162  0.424
2016 Devaiah BN, Case-Borden C, Gegonne A, Hsu CH, Chen Q, Meerzaman D, Dey A, Ozato K, Singer DS. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin. Nature Structural & Molecular Biology. PMID 27159561 DOI: 10.1038/Nsmb.3228  0.415
2016 White CL, Kessler PM, Dickerman BK, Ozato K, Sen GC. Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members. The Journal of Biological Chemistry. PMID 27137933 DOI: 10.1074/Jbc.M115.705467  0.455
2016 Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, et al. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular Cell. 61: 720-733. PMID 26942676 DOI: 10.1016/J.Molcel.2016.02.007  0.326
2015 Chang TH, Yoshimi R, Ozato K. Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6. Journal of Immunology (Baltimore, Md. : 1950). PMID 26503954 DOI: 10.4049/Jimmunol.1402064  0.424
2015 Bradfute SB, Anthony SM, Stuthman KS, Ayithan N, Tailor P, Shaia CI, Bray M, Ozato K, Bavari S. Mechanisms of immunity in post-exposure vaccination against Ebola virus infection. Plos One. 10: e0118434. PMID 25785602 DOI: 10.1371/Journal.Pone.0118434  0.307
2015 Gupta M, Shin DM, Ramakrishna L, Goussetis DJ, Platanias LC, Xiong H, Morse HC, Ozato K. IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes. Nature Communications. 6: 6379. PMID 25775030 DOI: 10.1038/Ncomms7379  0.39
2015 Ayithan N, Bradfute SB, Anthony SM, Stuthman KS, Bavari S, Bray M, Ozato K. Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection. Plos One. 10: e0118345. PMID 25719445 DOI: 10.1371/Journal.Pone.0118345  0.338
2015 Paschall AV, Zhang R, Qi CF, Bardhan K, Peng L, Lu G, Yang J, Merad M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse HC, Ozato K, Xiong H, et al. IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2369-79. PMID 25646302 DOI: 10.4049/Jimmunol.1402412  0.41
2015 Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes & Development. 29: 394-408. PMID 25637355 DOI: 10.1101/Gad.257592.114  0.422
2015 Sasaki H, Kurotaki D, Osato N, Sato H, Sasaki I, Koizumi S, Wang H, Kaneda C, Nishiyama A, Kaisho T, Aburatani H, Morse HC, Ozato K, Tamura T. Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells. Blood. 125: 358-69. PMID 25398936 DOI: 10.1182/Blood-2014-02-557983  0.404
2015 Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kaneko N, Koizumi S, Ozato K, Suzuki Y, Tamura T. Enhancer Landscape Dynamics and the Role of IRF8 in Mononuclear Phagocyte Development Blood. 126: 2384-2384. DOI: 10.1182/Blood.V126.23.2384.2384  0.448
2015 Paschall A, Zhang R, Bardhan K, Qi C, Peng L, Lu G, Yang J, Merad M, Zimmerman M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse H, Ozato K, et al. Abstract PR05: IRF8 regulates GM-CSF expression in T cells and tumor cells to mediate myeloid-derived suppressor cell differentiation Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr05  0.425
2015 Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kaneko N, Koizumi S, Ozato K, Suzuki Y, Tamura T. Enhancer landscape dynamics during monocyte and dendritic cell development and the role of the transcription factor IRF8 Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.266  0.379
2015 Sasaki H, Kurotaki D, Osato N, Sato H, Sasaki I, Koizumi S, Wang H, Kaneda C, Nishiyama A, Kaisho T, Aburatani H, Morse HC, Ozato K, Tamura T. A role of the transcription factor IRF8 in basophil and mast cell development Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.247  0.394
2015 Ozato K, Gupta M, Sarai N, Morse H, Platanias L, Xiong H, Bachu M. ID: 211 Cytokine. 76: 103. DOI: 10.1016/J.Cyto.2015.08.215  0.438
2014 Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K. BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nature Structural & Molecular Biology. 21: 1047-57. PMID 25383670 DOI: 10.1038/Nsmb.2912  0.384
2014 Kurotaki D, Yamamoto M, Nishiyama A, Uno K, Ban T, Ichino M, Sasaki H, Matsunaga S, Yoshinari M, Ryo A, Nakazawa M, Ozato K, Tamura T. IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils. Nature Communications. 5: 4978. PMID 25236377 DOI: 10.1038/Ncomms5978  0.388
2014 Wang H, Yan M, Sun J, Jain S, Yoshimi R, Abolfath SM, Ozato K, Coleman WG, Ng AP, Metcalf D, DiRago L, Nutt SL, Morse HC. A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 193: 1766-77. PMID 25024380 DOI: 10.4049/Jimmunol.1301939  0.385
2014 Yoshida Y, Yoshimi R, Yoshii H, Kim D, Dey A, Xiong H, Munasinghe J, Yazawa I, O'Donovan MJ, Maximova OA, Sharma S, Zhu J, Wang H, Morse HC, Ozato K. The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation. Immunity. 40: 187-98. PMID 24485804 DOI: 10.1016/J.Immuni.2013.11.022  0.381
2014 Ayithan N, Bradfute SB, Anthony SM, Stuthman KS, Dye JM, Bavari S, Bray M, Ozato K. Ebola virus-like particles stimulate type I interferons and proinflammatory cytokine expression through the toll-like receptor and interferon signaling pathways. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 79-89. PMID 24102579 DOI: 10.1089/Jir.2013.0035  0.37
2014 Wang H, Yan M, Sun J, Jain S, Yoshimi R, Abolfath SM, Ozato K, Coleman WG, Ng AP, Metcalf D, DiRago L, Nutt SL, Morse HC. Correction: A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation The Journal of Immunology. 193: 4749-4749. DOI: 10.4049/Jimmunol.1490036  0.367
2014 Yoshimi R, Yoshida Y, Yoshii H, Kim D, Dey A, Xiong H, Munasinghe J, Yazawa I, O'Donovan M, Maximova O, Sharma S, Zhu J, Wang H, Morse H, Ishigatsubo Y, ... Ozato K, et al. AB0050 Irf8 Promotes TH17 Differentiation via Activation of Integrin-Mediated Tgfbeta Signaling in Neuroinflammation Annals of the Rheumatic Diseases. 73: 820.2-820. DOI: 10.1136/Annrheumdis-2014-Eular.3457  0.389
2014 Ozato K, Kamada R, Patel M, Fujita T, Zhang Y, Tamura T, Zhu J. S-19 : Epigenetic regulation of interferon response Cytokine. 70: 25. DOI: 10.1016/J.Cyto.2014.07.239  0.422
2013 Alsarraj J, Faraji F, Geiger TR, Mattaini KR, Williams M, Wu J, Ha NH, Merlino T, Walker RC, Bosley AD, Xiao Z, Andresson T, Esposito D, Smithers N, Lugo D, ... ... Ozato K, et al. BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane. Plos One. 8: e80746. PMID 24260471 DOI: 10.1371/Journal.Pone.0080746  0.315
2013 Jaiswal H, Kaushik M, Sougrat R, Gupta M, Dey A, Verma R, Ozato K, Tailor P. Batf3 and Id2 have a synergistic effect on Irf8-directed classical CD8α+ dendritic cell development. Journal of Immunology (Baltimore, Md. : 1950). 191: 5993-6001. PMID 24227775 DOI: 10.4049/Jimmunol.1203541  0.388
2013 Raetz M, Kibardin A, Sturge CR, Pifer R, Li H, Burstein E, Ozato K, Larin S, Yarovinsky F. Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin. Journal of Immunology (Baltimore, Md. : 1950). 191: 4818-27. PMID 24078692 DOI: 10.4049/Jimmunol.1301301  0.352
2013 Sarai N, Nimura K, Tamura T, Kanno T, Patel MC, Heightman TD, Ura K, Ozato K. WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition. The Embo Journal. 32: 2392-406. PMID 23921552 DOI: 10.1038/Emboj.2013.176  0.424
2013 Jianjun Yang, Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, ... ... Ozato K, et al. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. The Journal of Experimental Medicine. 210: 1447-62. PMID 23797094 DOI: 10.1084/Jem.20122494  0.379
2013 Ng SS, Li A, Pavlakis GN, Ozato K, Kino T. Viral infection increases glucocorticoid-induced interleukin-10 production through ERK-mediated phosphorylation of the glucocorticoid receptor in dendritic cells: potential clinical implications. Plos One. 8: e63587. PMID 23667643 DOI: 10.1371/Journal.Pone.0063587  0.344
2013 Patel MC, Debrosse M, Smith M, Dey A, Huynh W, Sarai N, Heightman TD, Tamura T, Ozato K. BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genes. Molecular and Cellular Biology. 33: 2497-507. PMID 23589332 DOI: 10.1128/Mcb.01180-12  0.416
2013 Baccala R, Gonzalez-Quintial R, Blasius AL, Rimann I, Ozato K, Kono DH, Beutler B, Theofilopoulos AN. Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus. Proceedings of the National Academy of Sciences of the United States of America. 110: 2940-5. PMID 23382217 DOI: 10.1073/Pnas.1222798110  0.399
2013 Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Miyake N, Matsumoto N, Nakazawa M, Ozato K, Tamura T. Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood. 121: 1839-49. PMID 23319570 DOI: 10.1182/Blood-2012-06-437863  0.468
2013 Kurotaki D, Yamamoto M, Nishiyama A, Uno K, Sasaki H, Ozato K, Tamura T. IRF8 Restrains Monocyte-Dendritic Cell Progenitors from Differentiating into Neutrophils by Inhibiting C/EBPα Activity Blood. 122: 2438-2438. DOI: 10.1182/Blood.V122.21.2438.2438  0.4
2013 Sasaki H, Osato N, Sasaki I, Kaneda C, Sato H, Nishiyama A, Kaisho T, Aburatani H, Morse HC, Ozato K, Tamura T. The Transcription Factor IRF8 is a Key Transcription Factor for Basophil Development Blood. 122: 1197-1197. DOI: 10.1182/Blood.V122.21.1197.1197  0.414
2013 Sasaki H, Kurotak D, Sato H, Morse HC, Ozato K, Tamura T. 226: The transcription factor IRF8 is required for the development of basophils Cytokine. 63: 296. DOI: 10.1016/J.Cyto.2013.06.229  0.363
2013 Ozato K, Yoshimi R, Yoshida Y, Gupta M, Yoshii H, Munasinghe J, Maximova O, Xiong H, Wang H, Morse HC. 194: IRF8 regulates autophagy and activates microglia to exacerbate neuroinflammation Cytokine. 63: 288-289. DOI: 10.1016/J.Cyto.2013.06.197  0.377
2013 Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Nakazawa M, Miyake N, Matsumoto N, Ozato K, Tamura T. 154 : The IRF8-KLF4 transcription factor cascade is essential for the development of monocytes Cytokine. 63: 279. DOI: 10.1016/J.Cyto.2013.06.157  0.469
2012 Okamura D, Maeda I, Taniguchi H, Tokitake Y, Ikeda M, Ozato K, Mise N, Abe K, Noce T, Izpisua Belmonte JC, Matsui Y. Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells. Genes & Development. 26: 2477-82. PMID 23154982 DOI: 10.1101/Gad.202242.112  0.422
2012 Horiuchi M, Wakayama K, Itoh A, Kawai K, Pleasure D, Ozato K, Itoh T. Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia. Journal of Neuroinflammation. 9: 227. PMID 23020843 DOI: 10.1186/1742-2094-9-227  0.384
2012 Chang TH, Xu S, Tailor P, Kanno T, Ozato K. The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation. Journal of Immunology (Baltimore, Md. : 1950). 189: 3548-56. PMID 22942423 DOI: 10.4049/Jimmunol.1201104  0.429
2012 Masuda T, Tsuda M, Yoshinaga R, Tozaki-Saitoh H, Ozato K, Tamura T, Inoue K. IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype. Cell Reports. 1: 334-40. PMID 22832225 DOI: 10.1016/J.Celrep.2012.02.014  0.357
2012 Miyagawa F, Zhang H, Terunuma A, Ozato K, Tagaya Y, Katz SI. Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 12123-8. PMID 22783014 DOI: 10.1073/Pnas.1201453109  0.341
2012 Xu H, Zhu J, Smith S, Foldi J, Zhao B, Chung AY, Outtz H, Kitajewski J, Shi C, Weber S, Saftig P, Li Y, Ozato K, Blobel CP, Ivashkiv LB, et al. Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nature Immunology. 13: 642-50. PMID 22610140 DOI: 10.1038/Ni.2304  0.378
2012 Nishiyama A, Dey A, Tamura T, Ko M, Ozato K. Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress. Plos One. 7: e34719. PMID 22567088 DOI: 10.1371/Journal.Pone.0034719  0.301
2012 Devaiah BN, Lewis BA, Cherman N, Hewitt MC, Albrecht BK, Robey PG, Ozato K, Sims RJ, Singer DS. BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain. Proceedings of the National Academy of Sciences of the United States of America. 109: 6927-32. PMID 22509028 DOI: 10.1073/Pnas.1120422109  0.32
2012 Ozato K, Sarai N, Patel M, Debrosse M, Heightman T, Tamura T, Ura K. O029 Chromatin exchange in interferon induced transcription Cytokine. 59: 511. DOI: 10.1016/J.Cyto.2012.06.063  0.414
2011 Phung TT, Sugamata R, Uno K, Aratani Y, Ozato K, Kawachi S, Thanh Nguyen L, Nakayama T, Suzuki K. Key role of regulated upon activation normal T-cell expressed and secreted, nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells. Microbiology and Immunology. 55: 874-84. PMID 22039999 DOI: 10.1111/J.1348-0421.2011.00396.X  0.326
2011 Yamamoto M, Kato T, Hotta C, Nishiyama A, Kurotaki D, Yoshinari M, Takami M, Ichino M, Nakazawa M, Matsuyama T, Kamijo R, Kitagawa S, Ozato K, Tamura T. Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development. Plos One. 6: e25812. PMID 22003407 DOI: 10.1371/Journal.Pone.0025812  0.467
2011 Liang Q, Deng H, Li X, Wu X, Tang Q, Chang TH, Peng H, Rauscher FJ, Ozato K, Zhu F. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7. Journal of Immunology (Baltimore, Md. : 1950). 187: 4754-63. PMID 21940674 DOI: 10.4049/Jimmunol.1101704  0.42
2011 Ouyang X, Zhang R, Yang J, Li Q, Qin L, Zhu C, Liu J, Ning H, Shin MS, Gupta M, Qi CF, He JC, Lira SA, Morse HC, Ozato K, et al. Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nature Communications. 2: 314. PMID 21587231 DOI: 10.1038/Ncomms1311  0.367
2011 Ng SS, Chang TH, Tailor P, Ozato K, Kino T. Virus-induced differential expression of nuclear receptors and coregulators in dendritic cells: implication to interferon production. Febs Letters. 585: 1331-7. PMID 21492741 DOI: 10.1016/J.Febslet.2011.04.001  0.378
2011 Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, Szulc Z, Bielawska A, Ozato K, Bhalla K, Liu K. IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia. Cancer Research. 71: 2882-91. PMID 21487040 DOI: 10.1158/0008-5472.Can-10-2493  0.432
2011 Kim JY, Anderson ED, Huynh W, Dey A, Ozato K. Proteomic survey of ubiquitin-linked nuclear proteins in interferon-stimulated macrophages. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 619-28. PMID 21428739 DOI: 10.1089/Jir.2011.0006  0.372
2011 Alsarraj J, Walker RC, Webster JD, Geiger TR, Crawford NP, Simpson RM, Ozato K, Hunter KW. Deletion of the proline-rich region of the murine metastasis susceptibility gene Brd4 promotes epithelial-to-mesenchymal transition- and stem cell-like conversion. Cancer Research. 71: 3121-31. PMID 21389092 DOI: 10.1158/0008-5472.Can-10-4417  0.348
2011 Patel SR, Hendrickson JE, Smith NH, Cadwell CM, Ozato K, Morse HC, Yoshimi R, Zimring JC. Alloimmunization against RBC or PLT antigens is independent of TRIM21 expression in a murine model. Molecular Immunology. 48: 909-13. PMID 21269695 DOI: 10.1016/J.Molimm.2010.12.017  0.325
2011 Horiuchi M, Itoh A, Pleasure D, Ozato K, Itoh T. Cooperative contributions of interferon regulatory factor 1 (IRF1) and IRF8 to interferon-γ-mediated cytotoxic effects on oligodendroglial progenitor cells. Journal of Neuroinflammation. 8: 8. PMID 21261980 DOI: 10.1186/1742-2094-8-8  0.4
2011 Fragale A, Stellacci E, Ilari R, Remoli AL, Lanciotti A, Perrotti E, Shytaj I, Orsatti R, Lawrence HR, Lawrence NJ, Wu J, Rehli M, Ozato K, Battistini A. Critical role of IRF-8 in negative regulation of TLR3 expression by Src homology 2 domain-containing protein tyrosine phosphatase-2 activity in human myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 1951-62. PMID 21220691 DOI: 10.4049/Jimmunol.1000918  0.427
2011 Smith MA, Wright G, Wu J, Tailor P, Ozato K, Chen X, Wei S, Piskurich JF, Ting JP, Wright KL. Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation. The Journal of Biological Chemistry. 286: 7893-904. PMID 21216962 DOI: 10.1074/Jbc.M110.165431  0.463
2011 Kubota T, Matsuoka M, Xu S, Otsuki N, Takeda M, Kato A, Ozato K. PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms. The Journal of Biological Chemistry. 286: 8165-75. PMID 21199872 DOI: 10.1074/Jbc.M110.195255  0.449
2011 Ozato K, Chang T, Xu SX, Kubota T, Matsuoka M. CS13-1. SUMO Modification of IRF Family Proteins and Regulation of Anti-Viral Innate Immunity Cytokine. 56: 99. DOI: 10.1016/J.Cyto.2011.07.383  0.31
2011 Kurotaki D, Ichino M, Nishiyama A, Sato GR, Yamamoto M, Ozato K, Tamura T. PS2-016. Selective regulation of monocyte subsets by the transcription factor Interferon Regulatory Factor 8 Cytokine. 56: 67. DOI: 10.1016/J.Cyto.2011.07.176  0.362
2010 Umehara T, Nakamura Y, Wakamori M, Ozato K, Yokoyama S, Padmanabhan B. Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2. Febs Letters. 584: 3901-8. PMID 20709061 DOI: 10.1016/J.Febslet.2010.08.013  0.35
2010 Umehara T, Nakamura Y, Jang MK, Nakano K, Tanaka A, Ozato K, Padmanabhan B, Yokoyama S. Structural basis for acetylated histone H4 recognition by the human BRD2 bromodomain. The Journal of Biological Chemistry. 285: 7610-8. PMID 20048151 DOI: 10.1074/Jbc.M109.062422  0.385
2010 Alsarraj J, Walker RC, Crawford NPS, Webster JD, Simpson RM, Ozato K, Hunter KW. Abstract 5761: An alternative isoform of the metastasis susceptibility gene Brd4 promotes EMT and metastatic progression Cancer Research. 70: 5761-5761. DOI: 10.1158/1538-7445.Am10-5761  0.339
2010 Patel M, Debrosse M, Smith M, Dey A, WalterHuynh, Tamura T, Heightman T, Ozato K. SS3-7 Transcriptional regulation of interferon stimulated genes: Role of chromatin binding protein Brd4 Cytokine. 52: 16-16. DOI: 10.1016/J.Cyto.2010.07.071  0.427
2010 Ozato K, Sarai N, Patel M, Ayithan N, Tamura T. SS3-1 Chromatin dynamics in interferon signaling: Analysis of the histone H3.3 deposition Cytokine. 52: 15-15. DOI: 10.1016/J.Cyto.2010.07.065  0.301
2009 Kwon H, Thierry-Mieg D, Thierry-Mieg J, Kim HP, Oh J, Tunyaplin C, Carotta S, Donovan CE, Goldman ML, Tailor P, Ozato K, Levy DE, Nutt SL, Calame K, Leonard WJ. Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity. 31: 941-52. PMID 20064451 DOI: 10.1016/J.Immuni.2009.10.008  0.399
2009 Ozato K, Yoshimi R, Chang TH, Wang H, Atsumi T, Morse HC. Comment on "Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappa B-dependent cytokine expression in fibroblasts". Journal of Immunology (Baltimore, Md. : 1950). 183: 7619; author reply 7. PMID 20007569 DOI: 10.4049/Jimmunol.0990103  0.346
2009 Byun JS, Wong MM, Cui W, Idelman G, Li Q, De Siervi A, Bilke S, Haggerty CM, Player A, Wang YH, Thirman MJ, Kaberlein JJ, Petrovas C, Koup RA, Longo D, ... Ozato K, et al. Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. Proceedings of the National Academy of Sciences of the United States of America. 106: 19286-91. PMID 19880750 DOI: 10.1073/Pnas.0905469106  0.38
2009 Dey A, Nishiyama A, Karpova T, McNally J, Ozato K. Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription. Molecular Biology of the Cell. 20: 4899-909. PMID 19812244 DOI: 10.1091/Mbc.E09-05-0380  0.394
2009 Zhao B, Takami M, Yamada A, Wang X, Koga T, Hu X, Tamura T, Ozato K, Choi Y, Ivashkiv LB, Takayanagi H, Kamijo R. Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nature Medicine. 15: 1066-71. PMID 19718038 DOI: 10.1038/Nm.2007  0.357
2009 Chang TH, Kubota T, Matsuoka M, Jones S, Bradfute SB, Bray M, Ozato K. Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery. Plos Pathogens. 5: e1000493. PMID 19557165 DOI: 10.1371/Journal.Ppat.1000493  0.39
2009 Ozato K. PLZF outreach: a finger in interferon's pie. Immunity. 30: 757-8. PMID 19538924 DOI: 10.1016/J.Immuni.2009.06.003  0.409
2009 Yoshimi R, Chang TH, Wang H, Atsumi T, Morse HC, Ozato K. Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts. Journal of Immunology (Baltimore, Md. : 1950). 182: 7527-38. PMID 19494276 DOI: 10.4049/Jimmunol.0804121  0.429
2009 la Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. The Journal of Experimental Medicine. 206: 1227-35. PMID 19487420 DOI: 10.1084/Jem.20080912  0.371
2009 Kubota T, Matsuoka M, Chang TH, Bray M, Jones S, Tashiro M, Kato A, Ozato K. Ebolavirus VP35 interacts with the cytoplasmic dynein light chain 8. Journal of Virology. 83: 6952-6. PMID 19403681 DOI: 10.1128/Jvi.00480-09  0.306
2009 Tamura T, Smith M, Kanno T, Dasenbrock H, Nishiyama A, Ozato K. Inducible deposition of the histone variant H3.3 in interferon-stimulated genes. The Journal of Biological Chemistry. 284: 12217-25. PMID 19244243 DOI: 10.1074/Jbc.M805651200  0.42
2009 Kim JY, Ozato K. The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity. Journal of Immunology (Baltimore, Md. : 1950). 182: 2131-40. PMID 19201866 DOI: 10.4049/Jimmunol.0802755  0.395
2009 Huang B, Yang XD, Zhou MM, Ozato K, Chen LF. Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Molecular and Cellular Biology. 29: 1375-87. PMID 19103749 DOI: 10.1128/Mcb.01365-08  0.392
2009 La Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function (Journal of Experimental Medicine (2009) 206, 6, (1227-1235)) Journal of Experimental Medicine. 206: 1635. DOI: 10.1084/Jem.2008091262209C  0.303
2009 Carter SL, Kanno T, Ozato K, Campbell IL. IRF8 is present in microglia in the CNS and modulates the response of these cells to IFN-γ Cytokine. 48: 122. DOI: 10.1016/J.Cyto.2009.07.516  0.331
2009 Ozato K, Chang T, Kubota T, Matsuoka M, Bray M, Jones S. Inhibition of type I interferon transcription by IRF3/7 SUMOylation the process hijacked by the Ebola virus VP35 Cytokine. 48: 15. DOI: 10.1016/J.Cyto.2009.07.064  0.309
2008 Ozato K, Shin DM, Chang TH, Morse HC. TRIM family proteins and their emerging roles in innate immunity. Nature Reviews. Immunology. 8: 849-60. PMID 18836477 DOI: 10.1038/Nri2413  0.347
2008 Porrás A, Kozar S, Russanova V, Salpea P, Hirai T, Sammons N, Mittal P, Kim JY, Ozato K, Romero R, Howard BH. Developmental and epigenetic regulation of the human TLR3 gene. Molecular Immunology. 46: 27-36. PMID 18715647 DOI: 10.1016/J.Molimm.2008.06.030  0.415
2008 Kubota T, Matsuoka M, Chang TH, Tailor P, Sasaki T, Tashiro M, Kato A, Ozato K. Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression. The Journal of Biological Chemistry. 283: 25660-70. PMID 18635538 DOI: 10.1074/Jbc.M804479200  0.401
2008 Toyama R, Rebbert ML, Dey A, Ozato K, Dawid IB. Brd4 associates with mitotic chromosomes throughout early zebrafish embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 1636-44. PMID 18498094 DOI: 10.1002/Dvdy.21576  0.369
2008 Crawford NP, Alsarraj J, Lukes L, Walker RC, Officewala JS, Yang HH, Lee MP, Ozato K, Hunter KW. Bromodomain 4 activation predicts breast cancer survival. Proceedings of the National Academy of Sciences of the United States of America. 105: 6380-5. PMID 18427120 DOI: 10.1073/Pnas.0710331105  0.313
2008 Nishiyama A, Mochizuki K, Mueller F, Karpova T, McNally JG, Ozato K. Intracellular delivery of acetyl-histone peptides inhibits native bromodomain-chromatin interactions and impairs mitotic progression. Febs Letters. 582: 1501-7. PMID 18396160 DOI: 10.1016/J.Febslet.2008.03.044  0.333
2008 Mochizuki K, Nishiyama A, Jang MK, Dey A, Ghosh A, Tamura T, Natsume H, Yao H, Ozato K. The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase. The Journal of Biological Chemistry. 283: 9040-8. PMID 18223296 DOI: 10.1074/Jbc.M707603200  0.412
2008 Tailor P, Tamura T, Morse HC, Ozato K. The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse. Blood. 111: 1942-5. PMID 18055870 DOI: 10.1182/Blood-2007-07-100750  0.384
2008 Alter-Koltunoff M, Goren S, Nousbeck J, Feng CG, Sher A, Ozato K, Azriel A, Levi BZ. Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc. The Journal of Biological Chemistry. 283: 2724-33. PMID 18045875 DOI: 10.1074/Jbc.M707704200  0.432
2008 Maurice T, Duclot F, Meunier J, Naert G, Givalois L, Meffre J, Célérier A, Jacquet C, Copois V, Mechti N, Ozato K, Gongora C. Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1584-602. PMID 17805310 DOI: 10.1038/Sj.Npp.1301551  0.322
2008 Ozato K, Tailor P, Ramakrishna L, Chang T, Kubota T, Mayumimatsuoka, Herbertmorse C. PL-13 The mechanism of interferon gene transcription in dendritic cells Cytokine. 43: 277-277. DOI: 10.1016/J.Cyto.2008.07.219  0.401
2007 Gabriele L, Ozato K. The role of the interferon regulatory factor (IRF) family in dendritic cell development and function. Cytokine & Growth Factor Reviews. 18: 503-10. PMID 17702640 DOI: 10.1016/J.Cytogfr.2007.06.008  0.375
2007 Tailor P, Tamura T, Kong HJ, Kubota T, Kubota M, Borghi P, Gabriele L, Ozato K. The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8. Immunity. 27: 228-39. PMID 17702615 DOI: 10.1016/J.Immuni.2007.06.009  0.419
2007 Cho WK, Zhou M, Jang MK, Huang K, Jeong SJ, Ozato K, Brady JN. Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein. Journal of Virology. 81: 11179-86. PMID 17686863 DOI: 10.1128/Jvi.00408-07  0.369
2007 Kong HJ, Anderson DE, Lee CH, Jang MK, Tamura T, Tailor P, Cho HK, Cheong J, Xiong H, Morse HC, Ozato K. Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 179: 26-30. PMID 17579016 DOI: 10.4049/Jimmunol.179.1.26  0.4
2007 Ozato K, Tailor P, Kubota T. The interferon regulatory factor family in host defense: mechanism of action. The Journal of Biological Chemistry. 282: 20065-9. PMID 17502370 DOI: 10.1074/Jbc.R700003200  0.393
2007 Chen L, Calomeni E, Wen J, Ozato K, Shen R, Gao JX. Natural killer dendritic cells are an intermediate of developing dendritic cells. Journal of Leukocyte Biology. 81: 1422-33. PMID 17332372 DOI: 10.1189/Jlb.1106674  0.345
2007 Nagashima T, Maruyama T, Furuya M, Kajitani T, Uchida H, Masuda H, Ono M, Arase T, Ozato K, Yoshimura Y. Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis. Molecular Human Reproduction. 13: 141-8. PMID 17267518 DOI: 10.1093/Molehr/Gal115  0.312
2007 Dror N, Rave-Harel N, Burchert A, Azriel A, Tamura T, Tailor P, Neubauer A, Ozato K, Levi BZ. Interferon regulatory factor-8 is indispensable for the expression of promyelocytic leukemia and the formation of nuclear bodies in myeloid cells. The Journal of Biological Chemistry. 282: 5633-40. PMID 17189268 DOI: 10.1074/Jbc.M607825200  0.463
2007 Nakamura Y, Umehara T, Nakano K, Jang MK, Shirouzu M, Morita S, Uda-Tochio H, Hamana H, Terada T, Adachi N, Matsumoto T, Tanaka A, Horikoshi M, Ozato K, Padmanabhan B, et al. Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone H4. The Journal of Biological Chemistry. 282: 4193-201. PMID 17148447 DOI: 10.1074/Jbc.M605971200  0.377
2007 Dror N, Alter-Koltunoff M, Azriel A, Amariglio N, Jacob-Hirsch J, Zeligson S, Morgenstern A, Tamura T, Hauser H, Rechavi G, Ozato K, Levi BZ. Identification of IRF-8 and IRF-1 target genes in activated macrophages. Molecular Immunology. 44: 338-46. PMID 16597464 DOI: 10.1016/J.Molimm.2006.02.026  0.448
2006 Samarasinghe R, Tailor P, Tamura T, Kaisho T, Akira S, Ozato K. Induction of an anti-inflammatory cytokine, IL-10, in dendritic cells after toll-like receptor signaling. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 893-900. PMID 17238832 DOI: 10.1089/Jir.2006.26.893  0.315
2006 Masumi A, Fukazawa H, Shimazu T, Yoshida M, Ozato K, Komuro K, Yamaguchi K. Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation Oncogene. 25: 5113-5124. PMID 16582966 DOI: 10.1038/Sj.Onc.1209522  0.469
2006 Zhao J, Kong HJ, Li H, Huang B, Yang M, Zhu C, Bogunovic M, Zheng F, Mayer L, Ozato K, Unkeless J, Xiong H. IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. The Journal of Biological Chemistry. 281: 10073-80. PMID 16484229 DOI: 10.1074/Jbc.M507788200  0.352
2006 Tailor P, Tamura T, Ozato K. IRF family proteins and type I interferon induction in dendritic cells. Cell Research. 16: 134-40. PMID 16474425 DOI: 10.1038/Sj.Cr.7310018  0.371
2006 Nishiyama A, Dey A, Miyazaki J, Ozato K. Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin. Molecular Biology of the Cell. 17: 814-23. PMID 16339075 DOI: 10.1091/Mbc.E05-08-0729  0.352
2005 Kanno Y, Levi BZ, Tamura T, Ozato K. Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 770-9. PMID 16375605 DOI: 10.1089/Jir.2005.25.770  0.427
2005 Laricchia-Robbio L, Tamura T, Karpova T, Sprague BL, McNally JG, Ozato K. Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 14368-73. PMID 16183743 DOI: 10.1073/Pnas.0504014102  0.412
2005 Yang Z, Yik JH, Chen R, He N, Jang MK, Ozato K, Zhou Q. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Molecular Cell. 19: 535-45. PMID 16109377 DOI: 10.1016/J.Molcel.2005.06.029  0.344
2005 Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Molecular Cell. 19: 523-34. PMID 16109376 DOI: 10.1016/J.Molcel.2005.06.027  0.368
2005 Ishii KJ, Ito S, Tamura T, Hemmi H, Conover J, Ozato K, Akira S, Klinman DM. CpG-activated Thy1.2+ dendritic cells protect against lethal Listeria monocytogenes infection. European Journal of Immunology. 35: 2397-405. PMID 16047338 DOI: 10.1002/Eji.200425795  0.367
2005 McPhillips MG, Ozato K, McBride AA. Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin. Journal of Virology. 79: 8920-32. PMID 15994786 DOI: 10.1128/Jvi.79.14.8920-8932.2005  0.3
2005 Tamura T, Thotakura P, Tanaka TS, Ko MS, Ozato K. Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. Blood. 106: 1938-47. PMID 15947094 DOI: 10.1182/Blood-2005-01-0080  0.439
2005 Xiong H, Li H, Kong HJ, Chen Y, Zhao J, Xiong S, Huang B, Gu H, Mayer L, Ozato K, Unkeless JC. Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression. The Journal of Biological Chemistry. 280: 23531-9. PMID 15837792 DOI: 10.1074/Jbc.M414296200  0.409
2005 Baxter MK, McPhillips MG, Ozato K, McBride AA. The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4. Journal of Virology. 79: 4806-18. PMID 15795266 DOI: 10.1128/Jvi.79.8.4806-4818.2005  0.316
2005 Tamura T, Tailor P, Yamaoka K, Kong HJ, Tsujimura H, O'Shea JJ, Singh H, Ozato K. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. Journal of Immunology (Baltimore, Md. : 1950). 174: 2573-81. PMID 15728463 DOI: 10.4049/Jimmunol.174.5.2573  0.363
2005 Wang H, Lee CH, Qi C, Kerrikatte N, Tailor P, Ozato K, Morse HC. Transcription Factor ICSBP/IRF8 Regulates B Cell Development at Multiple Checkpoints. Blood. 106: 3314-3314. DOI: 10.1182/Blood.V106.11.3314.3314  0.379
2004 Liu J, Guan X, Tamura T, Ozato K, Ma X. Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein Journal of Biological Chemistry. 279: 55609-55617. PMID 15489234 DOI: 10.1074/Jbc.M406565200  0.402
2004 Farina A, Hattori M, Qin J, Nakatani Y, Minato N, Ozato K. Bromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localization. Molecular and Cellular Biology. 24: 9059-69. PMID 15456879 DOI: 10.1128/Mcb.24.20.9059-9069.2004  0.385
2004 Phair RD, Scaffidi P, Elbi C, Vecerová J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T. Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Molecular and Cellular Biology. 24: 6393-402. PMID 15226439 DOI: 10.1128/Mcb.24.14.6393-6402.2004  0.355
2004 Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM, Ozato K. Toll-Like Receptor 9 Signaling Activates NF-κB through IFN Regulatory Factor-8/IFN Consensus Sequence Binding Protein in Dendritic Cells Journal of Immunology. 172: 6820-6827. PMID 15153500 DOI: 10.4049/Jimmunol.172.11.6820  0.37
2004 Cui K, Tailor P, Liu H, Chen X, Ozato K, Zhao K. The chromatin-remodeling BAF complex mediates cellular antiviral activities by promoter priming. Molecular and Cellular Biology. 24: 4476-86. PMID 15121865 DOI: 10.1128/Mcb.24.10.4476-4486.2004  0.424
2004 Schmidt M, Bies J, Tamura T, Ozato K, Wolff L. The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells. Blood. 103: 4142-9. PMID 14976051 DOI: 10.1182/Blood-2003-01-0285  0.463
2004 Kanno T, Kanno Y, Siegel RM, Jang MK, Lenardo MJ, Ozato K. Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. Molecular Cell. 13: 33-43. PMID 14731392 DOI: 10.1016/S1097-2765(03)00482-9  0.363
2003 Tamura T, Kong HJ, Tunyaplin C, Tsujimura H, Calame K, Ozato K. ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells Blood. 102: 4547-4554. PMID 12933588 DOI: 10.1182/Blood-2003-01-0291  0.419
2003 Alter-Koltunoff M, Ehrlich S, Dror N, Azriel A, Eilers M, Hauser H, Bowen H, Barton CH, Tamura T, Ozato K, Levi BZ. Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1. The Journal of Biological Chemistry. 278: 44025-32. PMID 12904288 DOI: 10.1074/Jbc.M307954200  0.406
2003 Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 8758-63. PMID 12840145 DOI: 10.1073/Pnas.1433065100  0.766
2003 Masumi A, Yamakawa Y, Fukazawa H, Ozato K, Komuro K. Interferon regulatory factor-2 regulates cell growth through its acetylation. The Journal of Biological Chemistry. 278: 25401-7. PMID 12738767 DOI: 10.1074/Jbc.M213037200  0.432
2003 Tsujimura H, Tamura T, Ozato K. Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells Journal of Immunology. 170: 1131-1135. PMID 12538667 DOI: 10.4049/Jimmunol.170.3.1131  0.389
2003 Yamagoe S, Kanno T, Kanno Y, Sasaki S, Siegel RM, Lenardo MJ, Humphrey G, Wang Y, Nakatani Y, Howard BH, Ozato K. Interaction of histone acetylases and deacetylases in vivo. Molecular and Cellular Biology. 23: 1025-33. PMID 12529406 DOI: 10.1128/Mcb.23.3.1025-1033.2003  0.37
2003 Xiong H, Zhu C, Li H, Chen F, Mayer L, Ozato K, Unkeless JC, Plevy SE. Complex formation of the interferon (IFN) consensus sequence-binding protein with IRF-1 is essential for murine macrophage IFN-gamma-induced iNOS gene expression. The Journal of Biological Chemistry. 278: 2271-7. PMID 12429737 DOI: 10.1074/Jbc.M209583200  0.324
2003 Aliberti J, Schulz O, Pennington DJ, Tsujimura H, Sousa CRe, Ozato K, Sher A. Essential role for ICSBP in the in vivo development of murine CD8α+ dendritic cells Blood. 101: 305-310. PMID 12393690 DOI: 10.1182/Blood-2002-04-1088  0.383
2003 Tsujimura H, Tamura T, Gongora C, Aliberti J, Sousa CRe, Sher A, Ozato K. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood. 101: 961-969. PMID 12393459 DOI: 10.1182/Blood-2002-05-1327  0.435
2002 Masumi A, Tamaoki S, Wang IM, Ozato K, Komuro K. IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. Febs Letters. 531: 348-53. PMID 12417340 DOI: 10.1016/S0014-5793(02)03556-1  0.354
2002 Kuwata T, Gongora C, Kanno Y, Sakaguchi K, Tamura T, Kanno T, Basrur V, Martinez R, Appella E, Golub T, Ozato K. Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element. Molecular and Cellular Biology. 22: 7439-48. PMID 12370291 DOI: 10.1128/Mcb.22.21.7439-7448.2002  0.436
2002 Maruyama T, Farina A, Dey A, Cheong J, Bermudez VP, Tamura T, Sciortino S, Shuman J, Hurwitz J, Ozato K. A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase. Molecular and Cellular Biology. 22: 6509-20. PMID 12192049 DOI: 10.1128/Mcb.22.18.6509-6520.2002  0.383
2002 Tsujimura H, Nagamura-Inoue T, Tamura T, Ozato K. IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage Journal of Immunology. 169: 1261-1269. PMID 12133947 DOI: 10.4049/Jimmunol.169.3.1261  0.447
2002 Lefebvre B, Ozato K, Lefebvre P. Phosphorylation of histone H3 is functionally linked to retinoic acid receptor beta promoter activation. Embo Reports. 3: 335-40. PMID 11897660 DOI: 10.1093/Embo-Reports/Kvf066  0.414
2002 Tamura T, Ozato K. ICSBP/IRF-8: Its regulatory roles in the development of myeloid cells Journal of Interferon and Cytokine Research. 22: 145-152. PMID 11846985 DOI: 10.1089/107999002753452755  0.458
2002 Lefebvre B, Brand C, Lefebvre P, Ozato K. Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid X receptor. Molecular and Cellular Biology. 22: 1446-59. PMID 11839811 DOI: 10.1128/Mcb.22.5.1446-1459.2002  0.399
2002 Ozato K, Tsujimura H, Tamura T. Toll-like receptor signaling and regulation of cytokine gene expression in the immune system Biotechniques. 33. DOI: 10.2144/Oct0208  0.379
2001 Sciortino S, Gurtner A, Manni I, Fontemaggi G, Dey A, Sacchi A, Ozato K, Piaggio G. The cyclin B1 gene is actively transcribed during mitosis in HeLa cells Embo Reports. 2: 1018-1023. PMID 11606417 DOI: 10.1093/Embo-Reports/Kve223  0.396
2001 Ung TL, Cao C, Lu J, Ozato K, Dever TE. Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR Embo Journal. 20: 3728-3737. PMID 11447114 DOI: 10.1093/Emboj/20.14.3728  0.326
2001 Morse HC, Qi CF, Chattopadhyay SK, Hori M, Taddesse-Heath L, Ozato K, Hartley JW, Taylor BA, Ward JM, Jenkins NA, Copeland NG, Fredrickson TN. Combined histologic and molecular features reveal previously unappreciated subsets of lymphoma in AKXD recombinant inbred mice. Leukemia Research. 25: 719-33. PMID 11397479 DOI: 10.1016/S0145-2126(01)00022-4  0.306
2001 Nagamura-Inoue T, Tamura T, Ozato K. Transcription factors that regulate growth and differentiation of myeloid cells International Reviews of Immunology. 20: 83-105. PMID 11342299 DOI: 10.3109/08830180109056724  0.431
2001 Masumi A, Ozato K. Coactivator p300 Acetylates the Interferon Regulatory Factor-2 in U937 Cells following Phorbol Ester Treatment Journal of Biological Chemistry. 276: 20973-20980. PMID 11304541 DOI: 10.1074/Jbc.M101707200  0.454
2000 Kawagishi-Kobayashi M, Cao C, Lu J, Ozato K, Dever TE. Pseudosubstrate inhibition of protein kinase PKR by swine pox virus C8L gene product Virology. 276: 424-434. PMID 11040133 DOI: 10.1006/Viro.2000.0561  0.369
2000 Yamauchi T, Yamauchi J, Kuwata T, Tamura T, Yamashita T, Bae N, Westphal H, Ozato K, Nakatani Y. Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis Proceedings of the National Academy of Sciences of the United States of America. 97: 11303-11306. PMID 11027331 DOI: 10.1073/Pnas.97.21.11303  0.376
2000 Li M, Damania B, Alvarez X, Ogryzko V, Ozato K, Jung JU. Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor Molecular and Cellular Biology. 20: 8254-8263. PMID 11027294 DOI: 10.1128/Mcb.20.21.8254-8263.2000  0.308
2000 Tamura T, Nagamura-Inoue T, Shmeltzer Z, Kuwata T, Ozato K. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages Immunity. 13: 155-165. PMID 10981959 DOI: 10.1016/S1074-7613(00)00016-9  0.434
2000 Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K. A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G2-to-M transition Molecular and Cellular Biology. 20: 6537-6549. PMID 10938129 DOI: 10.1128/Mcb.20.17.6537-6549.2000  0.324
2000 Xu RH, Peng Y, Fan J, Yan D, Yamagoe S, Princler G, Sredni D, Ozato K, Kung HF. Histone acetylation is a checkpoint in FGF-stimulated mesoderm induction. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 628-35. PMID 10906781 DOI: 10.1002/1097-0177(2000)9999:9999<::Aid-Dvdy1024>3.0.Co;2-H  0.385
2000 Katagiri Y, Takeda K, Yu ZX, J. Ferrans V, Ozato K, Guroff G. Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B Nature Cell Biology. 2: 435-440. PMID 10878809 DOI: 10.1038/35017072  0.3
2000 Wang I, Contursi C, Masumi A, Ma X, Trinchieri G, Ozato K. An IFN-γ-Inducible Transcription Factor, IFN Consensus Sequence Binding Protein (ICSBP), Stimulates IL-12 p40 Expression in Macrophages Journal of Immunology. 165: 271-279. PMID 10861061 DOI: 10.4049/Jimmunol.165.1.271  0.396
2000 Blanco JC, Contursi C, Salkowski CA, DeWitt DL, Ozato K, Vogel SN. Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression. The Journal of Experimental Medicine. 191: 2131-44. PMID 10859338 DOI: 10.1084/Jem.191.12.2131  0.44
2000 Rubinstein YR, Driggers PH, Ogryzko VV, Thornton AM, Ozato K, Pontzer CH. An IFN regulatory factor-2 DNA-binding domain dominant negative mutant exhibits altered cell growth and gene expression. Oncogene. 19: 1411-8. PMID 10723132 DOI: 10.1038/Sj.Onc.1203435  0.395
2000 Contursi C, Wang I, Gabriele L, Gadina M, O'Shea J, Morse HC, Ozato K. IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages Proceedings of the National Academy of Sciences of the United States of America. 97: 91-96. PMID 10618376 DOI: 10.1073/Pnas.97.1.91  0.443
2000 Kuwata T, Wang I, Tamura T, Ponnamperuma RM, Levine R, Holmes KL, Morse HC, Luca LMD, Ozato K. Vitamin A deficiency in mice causes a systemic expansion of myeloid cells Blood. 95: 3349-3356. DOI: 10.1182/Blood.V95.11.3349.011K46_3349_3356  0.333
1999 Sasaki S, Lesoon-Wood LA, Dey A, Kuwata T, Weintraub BD, Humphrey G, Yang WM, Seto E, Yen PM, Howard BH, Ozato K. Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene. The Embo Journal. 18: 5389-98. PMID 10508171 DOI: 10.1093/Emboj/18.19.5389  0.396
1999 Gabriele L, Phung J, Fukumoto J, Segal D, Wang IM, Giannakakou P, Giese NA, Ozato K, Morse HC. Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein. The Journal of Experimental Medicine. 190: 411-21. PMID 10430629 DOI: 10.1084/Jem.190.3.411  0.373
1999 Masumi A, Wang I, Lefebvre B, Yang X, Nakatani Y, Ozato K. The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness Molecular and Cellular Biology. 19: 1810-1820. PMID 10022868 DOI: 10.1128/Mcb.19.3.1810  0.486
1998 Morawetz RA, Giese NA, Gabriele L, Rothman PB, Horak I, Ozato K, Morse HC. Relationship of cytokines and cytokine signaling to immunodeficiency disorders in the mouse Brazilian Journal of Medical and Biological Research. 31: 61-67. PMID 9686180 DOI: 10.1590/S0100-879X1998000100008  0.329
1998 Li M, Lee H, Guo J, Neipel F, Fleckenstein B, Ozato K, Jung JU. Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor Journal of Virology. 72: 5433-5440. PMID 9620998 DOI: 10.1128/Jvi.72.7.5433-5440.1998  0.417
1998 Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, Evans RM, Nakatani Y, Ozato K. The histone acetylase PCAF is a nuclear receptor coactivator. Genes & Development. 12: 1638-51. PMID 9620851 DOI: 10.1101/Gad.12.11.1638  0.358
1998 Pemrick SM, Abarzúa P, Kratzeisen C, Marks MS, Medin JA, Ozato K, Grippo JF. Characterization of the chimeric retinoic acid receptor RARalpha/VDR. Leukemia. 12: 554-62. PMID 9557614 DOI: 10.1038/Sj.Leu.2400937  0.354
1998 Minucci S, Wong J, Blanco JCG, Shi Y, Wolffe AP, Ozato K. Retinoid Receptor-Induced Alteration of the Chromatin Assembled on a Ligand-Responsive Promoter in Xenopus Oocytes Molecular Endocrinology. 12: 315-324. PMID 9514149 DOI: 10.1210/Mend.12.3.0074  0.381
1998 Leong GM, Wang KS, Marton MJ, Blanco JCG, Wang I, Rolfes RJ, Ozato K, Segars JH. Interaction between the retinoid X receptor and transcription factor IIB is ligand-dependent in vivo. Journal of Biological Chemistry. 273: 2296-2305. PMID 9442074 DOI: 10.1074/Jbc.273.4.2296  0.416
1997 Scharton-Kersten T, Contursi C, Masumi A, Sher A, Ozato K. Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction Journal of Experimental Medicine. 186: 1523-1534. PMID 9348310 DOI: 10.1084/Jem.186.9.1523  0.341
1997 Bhattacharyya N, Dey A, Minucci S, Zimmer A, John S, Hager G, Ozato K. Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter. Molecular and Cellular Biology. 17: 6481-90. PMID 9343411 DOI: 10.1128/Mcb.17.11.6481  0.338
1997 Minucci S, Horn V, Bhattacharyya N, Russanova V, Ogryzko VV, Gabriele L, Howard BH, Ozato K. A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 94: 11295-11300. PMID 9326603 DOI: 10.1073/Pnas.94.21.11295  0.358
1997 Martin BK, Chin KC, Olsen JC, Skinner CA, Dey A, Ozato K, Ting JP. Induction of MHC class I expression by the MHC class II transactivator CIITA. Immunity. 6: 591-600. PMID 9175837 DOI: 10.1016/S1074-7613(00)80347-7  0.329
1997 Jurutka PW, Hsieh JC, Remus LS, Whitfield GK, Thompson PD, Haussler CA, Blanco JC, Ozato K, Haussler MR. Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription factor IIB, in vitro. The Journal of Biological Chemistry. 272: 14592-9. PMID 9169418 DOI: 10.1074/Jbc.272.23.14592  0.388
1997 Nuñez SB, Medin JA, Braissant O, Kemp L, Wahli W, Ozato K, Segars JH. Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor Molecular and Cellular Endocrinology. 127: 27-40. PMID 9099898 DOI: 10.1016/S0303-7207(96)03980-9  0.357
1997 Sharf R, Meraro D, Azriel A, Thornton AM, Ozato K, Petricoin EF, Larner AC, Schaper F, Hauser H, Levi BZ. Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA. The Journal of Biological Chemistry. 272: 9785-92. PMID 9092512 DOI: 10.1074/Jbc.272.15.9785  0.429
1997 Sunaga S, Maki K, Lagasse E, Blanco JC, Ozato K, Miyazaki J, Ikuta K. Myeloid differentiation is impaired in transgenic mice with targeted expression of a dominant negative form of retinoid X receptor beta. British Journal of Haematology. 96: 19-30. PMID 9012684 DOI: 10.1046/J.1365-2141.1997.8692483.X  0.311
1997 Minucci S, Leid M, Toyama R, Saint-Jeannet JP, Peterson VJ, Horn V, Ishmael JE, Bhattacharyya N, Dey A, Dawid IB, Ozato K. Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression. Molecular and Cellular Biology. 17: 644-55. PMID 9001218 DOI: 10.1128/Mcb.17.2.644  0.346
1997 Dey A, Ozato K. Genomic footprinting of retinoic acid regulated promoters in embryonal carcinoma cells Methods: a Companion to Methods in Enzymology. 11: 197-204. PMID 8993032 DOI: 10.1006/Meth.1996.0406  0.399
1996 Blanco JCG, Dey A, Leid M, Minucci S, Park BK, Jurutka PW, Haussler MR, Ozato K. Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR. Genes to Cells. 1: 209-221. PMID 9140065 DOI: 10.1046/J.1365-2443.1996.D01-229.X  0.381
1996 Samuel CE, Ozato K. Induction of interferons and interferon-induced genes Biotherapy. 8: 183-187. PMID 8962798 DOI: 10.1007/Bf01877203  0.373
1996 Minucci S, Ozato K. Retinoid receptors in transcriptional regulation Current Opinion in Genetics and Development. 6: 567-574. PMID 8939720 DOI: 10.1016/S0959-437X(96)80085-2  0.319
1996 Wang IM, Blanco JCG, Tsai SY, Tsai MJ, Ozato K. Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro Molecular and Cellular Biology. 16: 6313-6324. PMID 8887661  0.379
1996 Holtschke T, Löhler J, Kanno Y, Fehr T, Giese N, Rosenbauer F, Lou J, Knobeloch KP, Gabriele L, Waring JF, Bachmann MF, Zinkernagel RM, Morse HC, Ozato K, Horak I. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell. 87: 307-17. PMID 8861914 DOI: 10.1016/S0092-8674(00)81348-3  0.382
1996 Horn V, Minucci S, Ogryzko VV, Adamson ED, Howard BH, Levin AA, Ozato K. Rar And Rxr Selective Ligands Cooperatively Induce Apoptosis And Neuronal Differentiation In P19 Embryonal Carcinoma Cells The Faseb Journal. 10: 1071-1077. PMID 8801169 DOI: 10.1096/Fasebj.10.9.8801169  0.311
1996 Hallenbeck PL, Minucci S, Lippoldt R, Phyillaier M, Horn V, Ozato K, Nikodem VM. Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor α (RXRα) and RXRβ: Role of cell type and RXR domains Journal of Biological Chemistry. 271: 10503-10507. PMID 8631847 DOI: 10.1074/Jbc.271.18.10503  0.43
1996 Thornton AM, Buller RML, DeVico AL, Wang IM, Ozato K. Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells Proceedings of the National Academy of Sciences of the United States of America. 93: 383-387. PMID 8552643 DOI: 10.1073/Pnas.93.1.383  0.381
1996 Minucci S, Botquin V, Yeom YI, Dey A, Sylvester I, Zand DJ, Ohbo K, Ozato K, Schöler HR. Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo. The Embo Journal. 15: 888-899. DOI: 10.1002/J.1460-2075.1996.Tb00423.X  0.425
1996 Drew PP, Franzogo G, Biddison, Siebenlist U, Ozato K. Interferon regulatory factor and nfkb proteins physically interact and coordinately regulate major histocompatibility class I gene expression Faseb Journal. 10.  0.314
1995 Drew PD, Franzoso G, Becker KG, Bours V, Carlson LM, Siebenlist U, Ozato K. NF kappa B and interferon regulatory factor 1 physically interact and synergistically induce major histocompatibility class I gene expression. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 15: 1037-45. PMID 8746784 DOI: 10.1089/Jir.1995.15.1037  0.388
1995 Drew PD, Franzoso G, Carlson LM, Biddison WE, Siebenlist U, Ozato K. Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells. Journal of Neuroimmunology. 63: 157-62. PMID 8550813 DOI: 10.1016/0165-5728(95)00140-9  0.418
1995 Blanco JC, Wang IM, Tsai SY, Tsai MJ, O'Malley BW, Jurutka PW, Haussler MR, Ozato K. Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America. 92: 1535-9. PMID 7878015 DOI: 10.1073/Pnas.92.5.1535  0.389
1995 Nagata T, Weiss EH, Abe K, Kitagawa K, Ando A, Yara-Kikuti Y, Seldin MF, Ozato K, Inoko H, Taketo M. Physical mapping of the retinoid X receptor B gene in mouse and human Immunogenetics. 41: 83-90. PMID 7806300 DOI: 10.1007/Bf00182317  0.357
1995 Nunez SB, Medin JA, Wang HKK, Ozato K, Wahli W, Segars J. Retinoid X receptor β and peroxisome proliferator-activated receptor activate an estrogen response element Recent Progress in Hormone Research. 50: 409-415. PMID 7740175 DOI: 10.1016/B978-0-12-571150-0.50029-9  0.341
1995 Yang Y, Minucci S, Ozato K, Heyman RA, Ashwell JD. Efficient inhibition of activation-induced Fas ligand up-regulation and T cell apoptosis by retinoids requires occupancy of both retinoid X receptors and retinoic acid receptors Journal of Biological Chemistry. 270: 18672-18677. PMID 7629199 DOI: 10.1074/Jbc.270.31.18672  0.324
1995 Martínez-Balbás MA, Dey A, Rabindran SK, Ozato K, Wu C. Displacement of sequence-specific transcription factors from mitotic chromatin Cell. 83: 29-38. PMID 7553870 DOI: 10.1016/0092-8674(95)90231-7  0.431
1995 Bovolenta C, Lou J, Kanno Y, Park BK, Thornton AM, Coligan JE, Schubert M, Ozato K. Vesicular stomatitis virus infection induces a nuclear DNA-binding factor specific for the interferon-stimulated response element. Journal of Virology. 69: 4173-81. PMID 7539506 DOI: 10.1128/Jvi.69.7.4173-4181.1995  0.442
1995 Jungwirth C, Rebbert M, Ozato K, Degen HJ, Schultz U, Dawid IB. Chicken interferon consensus sequence-binding protein (ICSBP) and interferon regulatory factor (IRF) 1 genes reveal evolutionary conservation in the IRF gene family. Proceedings of the National Academy of Sciences of the United States of America. 92: 3105-9. PMID 7536924 DOI: 10.1073/Pnas.92.8.3105  0.4
1994 Krey G, Keller H, Mahfoudi A, Medin J, Ozato K, Dreyer C, Wahli W. Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids. The Journal of Steroid Biochemistry and Molecular Biology. 47: 65-73. PMID 8274443 DOI: 10.1016/0960-0760(93)90058-5  0.345
1994 Minucci S, Zand DJ, Dey A, Marks MS, Nagata T, Grippo JF, Ozato K. Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells. Molecular and Cellular Biology. 14: 360-72. PMID 8264603 DOI: 10.1128/Mcb.14.1.360  0.355
1994 Nagata T, Kanno Y, Ozato K, Taketo M. The mouse Rxrb gene encoding RXRβ: genomic organization and two mRNA isoforms generated by alternative splicing of transcripts initiated from CpG island promoters Gene. 142: 183-189. PMID 8194750 DOI: 10.1016/0378-1119(94)90259-3  0.36
1994 Politis AD, Ozato K, Coligan JE, Vogel SN. Regulation of IFN-γ-induced nuclear expression of IFN consensus sequence binding protein in murine peritoneal macrophages Journal of Immunology. 152: 2270-2278. PMID 8133040  0.314
1994 Lee IJ, Driggers PH, Medin JA, Nikodem VM, Ozato K. Recombinant thyroid hormone receptor and retinoid X receptor stimulate ligand-dependent transcription in vitro Proceedings of the National Academy of Sciences of the United States of America. 91: 1647-1651. PMID 8127860 DOI: 10.1073/Pnas.91.5.1647  0.352
1994 Dey A, Minucci S, Ozato K. Ligand-dependent occupancy of the retinoic acid receptor β2 promoter in vivo Molecular and Cellular Biology. 14: 8191-8201. PMID 7969156 DOI: 10.1128/Mcb.14.12.8191  0.309
1994 Yang Y, Minucci S, Zand DJ, Ozato K, Ashwell JD. T cell activation and increases in protein kinase C activity enhance retinoic acid-induced gene transcription Molecular Endocrinology. 8: 1370-1376. PMID 7854354 DOI: 10.1210/Mend.8.10.7854354  0.376
1994 Kalvakolanu DV, Mannino SB, Thornton A, Ozato K, Borden EC. Transcriptional induction of genes by IFN-β in mouse cells is regulated by a transcription factor similar to human ISGF-3 Antiviral Research. 25: 91-103. PMID 7847880 DOI: 10.1016/0166-3542(94)90099-X  0.428
1994 Medin JA, Minucci S, Driggers PH, Lee IJ, Ozato K. Quantitative increases in DNA binding affinity and positional effects determine 9-cis retinoic acid induced activation of the retinoid X receptorβ homodimer Molecular and Cellular Endocrinology. 105: 27-35. PMID 7821715 DOI: 10.1016/0303-7207(94)90032-9  0.351
1993 Kantorow M, Becker K, Sax CM, Ozato K, Piatigorsky J. Binding of tissue-specific forms of αA-CRYBP1 to their regulatory sequence in the mouse αA-crystallin-encoding gene: double-label immunoblotting of UV-crosslinked complexes Gene. 131: 159-165. PMID 8406008 DOI: 10.1016/0378-1119(93)90289-F  0.391
1993 Keller H, Mahfoudi A, Dreyer C, Hihi AK, Medin J, Ozato K, Wahli W. Peroxisome proliferator-activated receptors and lipid metabolism. Annals of the New York Academy of Sciences. 684: 157-73. PMID 8391237 DOI: 10.1111/J.1749-6632.1993.Tb32279.X  0.327
1993 Segars JH, Marks MS, Hirschfeld S, Driggers PH, Martinez E, Grippo JF, Brown M, Wahli W, Ozato K. Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways. Molecular and Cellular Biology. 13: 2258-68. PMID 8384307 DOI: 10.1128/Mcb.13.4.2258  0.321
1993 Kanno Y, Kozak CA, Schindler C, Driggers PH, Ennist DL, Gleason SL, Darnell JE, Ozato K. The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds. Molecular and Cellular Biology. 13: 3951-63. PMID 8321202 DOI: 10.1128/Mcb.13.7.3951  0.405
1993 Massa PT, Ozato K, McFarlin DE. Cell type-specific regulation of major histocompatibility complex (MHC) class I gene expression in astrocytes, oligodendrocytes, and neurons Glia. 8: 201-207. PMID 8225560 DOI: 10.1002/Glia.440080307  0.395
1993 Nelson N, Marks MS, Driggers PH, Ozato K. Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription. Molecular and Cellular Biology. 13: 588-99. PMID 7678054 DOI: 10.1128/Mcb.13.1.588  0.467
1993 Massa PT, Hirschfeld S, Levi BZ, Quigley LA, Ozato K, McFarlin DE. Expression of major histocompatibility complex (MHC) class I genes in astrocytes correlates with the presence of nuclear factors that bind to constitutive and inducible enhancers. Journal of Neuroimmunology. 41: 35-42. PMID 1460091 DOI: 10.1016/0165-5728(92)90193-O  0.387
1992 Nagata T, Segars JH, Levi BZ, Ozato K. Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 89: 937-941. PMID 1736309 DOI: 10.1073/Pnas.89.3.937  0.441
1992 Miller AE, Ennist DL, Ozato K, Westphal H. Activation of immunoglobulin control elements in transgenic mice. Immunogenetics. 35: 24-32. PMID 1729170 DOI: 10.1007/Bf00216623  0.414
1992 Dey A, Thornton AM, Lonergan M, Weissman SM, Chamberlain JW, Ozato K. Occupancy of upstream regulatory sites in vivo coincides with major histocompatibility complex class I gene expression in mouse tissues. Molecular and Cellular Biology. 12: 3590-9. PMID 1630463 DOI: 10.1128/mcb.12.8.3590-3599.1992  0.397
1992 Hallenbeck PL, Marks MS, Lippoldt RE, Ozato K, Nikodem VM. Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXR beta) enhances DNA binding and TH-dependent transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 89: 5572-6. PMID 1608968 DOI: 10.1073/Pnas.89.12.5572  0.368
1992 Driggers PH, Elenbaas BA, An Jb, Lee IJ, Ozato K. Two upstream elements activate transcription of a major histocompatibility complex class I gene in vitro Nucleic Acids Research. 20: 2533-2540. PMID 1598211 DOI: 10.1093/Nar/20.10.2533  0.42
1992 Marks MS, Levi BZ, Segars JH, Driggers PH, Hirschfeld S, Nagata T, Appella E, Ozato K. H-2RIIBP expressed from a baculovirus vector binds to multiple hormone response elements. Molecular Endocrinology (Baltimore, Md.). 6: 219-30. PMID 1569965 DOI: 10.1210/Mend.6.2.1569965  0.38
1992 Zoller B, Ozato K, Kroemer G, Auffray C, Jungwirth C. Interferon induction of chicken MHC class I gene expression: Phylogenetic conservation of the interferon-responsive element Virology. 191: 141-149. PMID 1384229 DOI: 10.1016/0042-6822(92)90175-O  0.368
1992 Flanagan JR, Becker KG, Ennist DL, Gleason SL, Driggers PH, Levi BZ, Appella E, Ozato K. Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus. Molecular and Cellular Biology. 12: 38-44. PMID 1309593 DOI: 10.1128/Mcb.12.1.38  0.444
1992 Marks MS, Hallenbeck PL, Nagata T, Segars J, Appella E, Nikodem VM, Ozato K. H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes. The Embo Journal. 11: 1419-1435. DOI: 10.1002/J.1460-2075.1992.Tb05187.X  0.355
1991 Flanagan JR, Murata M, Burke PA, Shirayoshi Y, Appella E, Sharp PA, Ozato K. Negative regulation of the major histocompatibility complex class I promoter in embryonal carcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 88: 3145-3149. PMID 2014233 DOI: 10.1073/Pnas.88.8.3145  0.405
1991 Dey A, Nebert DW, Ozato K. The AP-1 site and the cAMP- and serum response elements of the c-fos gene are constitutively occupied in vivo Dna and Cell Biology. 10: 537-544. PMID 1832543 DOI: 10.1089/Dna.1991.10.537  0.361
1990 Driggers PH, Ennist DL, Gleason SL, Mak WH, Marks MS, Levi BZ, Flanagan JR, Appella E, Ozato K. An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proceedings of the National Academy of Sciences of the United States of America. 87: 3743-7. PMID 2111015 DOI: 10.1073/Pnas.87.10.3743  0.438
1990 Rosner MH, Vigano MA, Ozato K, Timmons PM, Poirier F, Rigby PW, Staudt LM. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 345: 686-92. PMID 1972777 DOI: 10.1038/345686A0  0.403
1990 Nakamura T, Donovan DM, Hamada K, Sax CM, Norman B, Flanagan JR, Ozato K, Westphal H, Piatigorsky J. Regulation of the Mouse αA-Crystallin Gene: Isolation of a cDNA Encoding a Protein That Binds to a cis Sequence Motif Shared with the Major Histocompatibility Complex Class I Gene and Other Genes Molecular and Cellular Biology. 10: 3700-3708. PMID 1694016 DOI: 10.1128/mcb.10.7.3700-3708.1990  0.39
1989 Levi BZ, Kasik JW, Burke PA, Prywes R, Roeder RG, Appella E, Ozato K. Neonatal induction of a nuclear protein that binds to the c-fos enhancer. Proceedings of the National Academy of Sciences of the United States of America. 86: 2262-6. PMID 2928331 DOI: 10.1073/Pnas.86.7.2262  0.329
1989 Burke PA, Hirschfeld S, Shirayoshi Y, Kasik JW, Hamada K, Appella E, Ozato K. Developmental and tissue-specific expression of nuclear proteins that bind the regulatory element of the major histocompatibility complex class I gene Journal of Experimental Medicine. 169: 1309-1321. PMID 2926327 DOI: 10.1084/Jem.169.4.1309  0.395
1989 Hamada K, Gleason SL, Levi BZ, Hirschfeld S, Appella E, Ozato K. H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element Proceedings of the National Academy of Sciences of the United States of America. 86: 8289-8293. PMID 2554307 DOI: 10.1073/Pnas.86.21.8289  0.382
1989 Neuhold LA, Shirayoshi Y, Ozato K, Jones JE, Nebert DW. Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction Molecular and Cellular Biology. 9: 2378-2386. PMID 2548080 DOI: 10.1128/Mcb.9.6.2378  0.383
1989 Massa PT, Cowan EP, Levi BZ, Ozato K, McFarlin DE. Genetic regulation of class I major histocompatibility complex (MHC) antigen induction on astrocytes Journal of Neuroimmunology. 24: 125-132. PMID 2478575 DOI: 10.1016/0165-5728(89)90106-9  0.35
1988 Levi BZ, Kasik JW, Ozato K. c-fos antisense RNA blocks expression of c-fos gene in F9 embryonal carcinoma cells Cell Differentiation and Development. 25: 95-101. PMID 2463066 DOI: 10.1016/0922-3371(88)90105-0  0.33
1988 Shirayoshi Y, Burke PA, Appella E, Ozato K. Interferon-induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence Proceedings of the National Academy of Sciences of the United States of America. 85: 5884-5888. PMID 2457903 DOI: 10.1073/Pnas.85.16.5884  0.421
1988 Levi BZ, Ozato K. Constitutive expression of c-fos antisense RNA blocks c-fos gene induction by interferon and by phorbol ester and reduces c-myc expression in F9 embryonal carcinoma cells Genes &Amp; Development. 2: 554-566. PMID 2454869 DOI: 10.1101/Gad.2.5.554  0.305
1988 Wan YJY, Levi BZ, Ozato K. Induction of c-fos gene expression by interferons Journal of Interferon Research. 8: 105-112. PMID 2452846 DOI: 10.1089/Jir.1988.8.105  0.372
1988 Kaufmann Y, Silverman T, Levi B-, Ozato K. Induction of c‐ets and c‐fos Gene Expression upon Antigenic Stimulation of a Memory‐like Cytolytic Hybridoma Annals of the New York Academy of Sciences. 532: 432-435. DOI: 10.1111/J.1749-6632.1988.Tb36366.X  0.335
1987 Shirayoshi Y, Miyazaki J, Burke PA, Hamada K, Appella E, Ozato K. Binding of multiple nuclear factors to the 5' upstream regulatory element of the murine major histocompatibility class I gene Molecular and Cellular Biology. 7: 4542-4548. PMID 3501825 DOI: 10.1128/Mcb.7.12.4542  0.424
1987 Kaufmann Y, Silverman T, Levi BZ, Ozato K. Induction of c-ets and c-fos gene expression upon antigenic stimulation of a T cell hybridoma with inducible cytolytic capacity Journal of Experimental Medicine. 166: 810-815. PMID 3498003 DOI: 10.1084/Jem.166.3.810  0.323
1987 Sugita K, Miyazaki J, Appella E, Ozato K. Interferons increase transcription of a major histocompatibility class I gene via a 5' interferon consensus sequence Molecular and Cellular Biology. 7: 2625-2630. PMID 3475569 DOI: 10.1128/Mcb.7.7.2625  0.388
1987 Kasik JW, Wan YJ, Ozato K. A burst of c-fos gene expression in the mouse occurs at birth Molecular and Cellular Biology. 7: 3349-3352. PMID 3313015 DOI: 10.1128/Mcb.7.9.3349  0.304
1987 Wan YJY, Orrison BM, Lieberman R, Lazarovici P, Ozato K. Induction of major histocompatibility Class I antigens by interferons in undifferentiated F9 cells Journal of Cellular Physiology. 130: 276-283. PMID 3102507 DOI: 10.1002/Jcp.1041300214  0.395
1987 Koeller D, Lieberman R, Miyazaki JI, Appella E, Ozato K, Mann DW, Forman J. Introduction of H-2Dd determinants into the H-2Ld antigen by site-directed mutagenesis. Journal of Experimental Medicine. 166: 744-760. PMID 2442290 DOI: 10.1084/Jem.166.3.744  0.303
1986 Miyazaki JI, Appella E, Ozato K. Intracellular transport blockade caused by disruption of the disulfide bridge in the third external domain of major histocompatibility complex class I antigen Proceedings of the National Academy of Sciences of the United States of America. 83: 757-761. PMID 3080749 DOI: 10.1073/Pnas.83.3.757  0.315
1986 Miyazaki JI, Appella E, Zhao H, Forman J, Ozato K. Expression and function of a nonglycosylated major histocompatibility class I antigen Journal of Experimental Medicine. 163: 856-871. PMID 2419473 DOI: 10.1084/Jem.163.4.856  0.349
1985 Ozato K, Wan YJ, Orrison BM. Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon Proceedings of the National Academy of Sciences of the United States of America. 82: 2427-2431. PMID 2581247 DOI: 10.1073/Pnas.82.8.2427  0.335
1984 Shiroishi T, Evans GA, Appella E, Ozato K. Role of a disulfide bridge in the immune function of major histocompatibility class I antigen as studied by in vitro mutagenesis Proceedings of the National Academy of Sciences of the United States of America. 81: 7544-7548. PMID 6334311 DOI: 10.1073/Pnas.81.23.7544  0.338
1984 Murre C, Choi E, Weis J, Seidman JG, Ozato K, Liu L, Burakoff SJ, Reiss CS. Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains Journal of Experimental Medicine. 160: 167-178. PMID 6203998 DOI: 10.1084/Jem.160.1.167  0.316
1983 Hansen TH, Ozato K, Sachs DH. Heterogeneity of H-2D region associated genes and gene products. Advances in Immunology. 34: 39-70. PMID 6195894 DOI: 10.1016/S0065-2776(08)60376-4  0.311
1983 Tanaka K, Ozato K, Jay G, Parnes JR, Ramanathan L, Seidman JG, Chang KS, Appella E. Control of H-2 antigen and beta 2-microglobulin gene expression in mouse trophoblast cell clones. Proceedings of the National Academy of Sciences of the United States of America. 80: 5597-601. PMID 6193518 DOI: 10.1073/Pnas.80.18.5597  0.362
1983 Ozato K, Evans GA, Shykind B, Margulies DH, Seidman JG. Hybrid H-2 histocompatibility gene products assign domains recognized by alloreactive T cells Proceedings of the National Academy of Sciences of the United States of America. 80: 2040-2043. PMID 6188160 DOI: 10.1073/Pnas.80.7.2040  0.339
1982 Evans GA, Margulies DH, Camerini-Otero RD, Ozato K, Seidman JG. Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld. Proceedings of the National Academy of Sciences of the United States of America. 79: 1994-8. PMID 6952248 DOI: 10.1073/Pnas.79.6.1994  0.332
1982 Evans GA, Margulies DH, Shykind B, Seidman JG, Ozato K. Exon shuffling: Mapping polymorphic determinants on hybrid mouse transplantation antigens Nature. 300: 755-757. PMID 6184620 DOI: 10.1038/300755A0  0.336
1981 Epstein SL, Ozato K, Bluestone JA, Sachs DH. Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses Journal of Experimental Medicine. 154: 397-410. PMID 6790657 DOI: 10.1084/Jem.154.2.397  0.303
1977 Ozato K, Cebra J, Ebert JD. Cell-mediated mitogenic response induced by leukoagglutinin and Lens culinaris lectin in mouse lymphocytes. The Journal of Experimental Medicine. 146: 779-91. PMID 302308 DOI: 10.1084/Jem.146.3.779  0.364
1976 Ozato K, Ebert JD, Adler WH. The differentiation of suppressor cell populations as revealed by studies of the effects of mitogens on the mixed lymphocyte reaction and on the generation of cytotoxic lymphocytes. Cellular Immunology. 22: 323-33. PMID 132276 DOI: 10.1016/0008-8749(76)90033-2  0.355
1976 Ozato K, Ebert JD. Concanavalin A potentiates syngeneic response in murine lymphocytes. The Journal of Experimental Medicine. 143: 1-14. PMID 127828 DOI: 10.1084/Jem.143.1.1  0.355
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