| Year |
Citation |
Score |
| 2020 |
Charubin K, Modla S, Caplan JL, Papoutsakis ET. Interspecies Microbial Fusion and Large-Scale Exchange of Cytoplasmic Proteins and RNA in a Syntrophic Clostridium Coculture. Mbio. 11. PMID 32873766 DOI: 10.1128/Mbio.02030-20 |
0.322 |
|
| 2020 |
Bennett RK, Agee A, Gerald Har JR, von Hagel B, Siu KH, Antoniewicz MR, Papoutsakis ET. Triggering the stringent response enhances synthetic methanol utilization in Escherichia coli. Metabolic Engineering. 61: 1-10. PMID 32360074 DOI: 10.1016/J.Ymben.2020.04.007 |
0.322 |
|
| 2020 |
Bennett RK, Dillon M, Gerald Har JR, Agee A, von Hagel B, Rohlhill J, Antoniewicz MR, Papoutsakis ET. Engineering Escherichia coli for methanol-dependent growth on glucose for metabolite production. Metabolic Engineering. PMID 32179162 DOI: 10.1016/J.Ymben.2020.03.003 |
0.341 |
|
| 2019 |
Rohlhill J, Gerald Har JR, Antoniewicz MR, Papoutsakis ET. Improving synthetic methylotrophy via dynamic formaldehyde regulation of pentose phosphate pathway genes and redox perturbation. Metabolic Engineering. PMID 31881281 DOI: 10.1016/J.Ymben.2019.12.006 |
0.425 |
|
| 2019 |
Streett HE, Kalis KM, Papoutsakis ET. A strongly fluorescing anaerobic reporter and protein-tagging system for organisms based on the Fluorescence-Activating and Absorption-Shifting Tag (FAST) protein. Applied and Environmental Microbiology. PMID 31076434 DOI: 10.1128/Aem.00622-19 |
0.332 |
|
| 2018 |
Diaz CAC, Bennett RK, Papoutsakis ET, Antoniewicz MR. Deletion of four genes in Escherichia coli enables preferential consumption of xylose and secretion of glucose. Metabolic Engineering. 52: 168-177. PMID 30529131 DOI: 10.1016/J.Ymben.2018.12.003 |
0.311 |
|
| 2018 |
Kao CY, Papoutsakis ET. Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and progenitor cells. Science Advances. 4: eaau6762. PMID 30417099 DOI: 10.1126/Sciadv.Aau6762 |
0.304 |
|
| 2018 |
Charubin K, Papoutsakis ET. Direct cell-to-cell exchange of matter in a synthetic Clostridium syntrophy enables CO fixation, superior metabolite yields, and an expanded metabolic space. Metabolic Engineering. 52: 9-19. PMID 30391511 DOI: 10.1016/J.Ymben.2018.10.006 |
0.376 |
|
| 2018 |
Jones AJ, Fast AG, Clupper M, Papoutsakis ET. Small, low, but potent: the complex regulatory role of the small RNA SolB on solventogenesis in . Applied and Environmental Microbiology. PMID 29728392 DOI: 10.1128/Aem.00597-18 |
0.416 |
|
| 2018 |
Fast AG, Papoutsakis ET. Functional Expression of the Clostridium ljungdahlii Acetyl-CoA Synthase in Clostridium acetobutylicum as Demonstrated by a Novel In Vivo CO Exchange Activity, on the Way to Heterologous Installation of a Functional Wood-Ljungdahl Pathway. Applied and Environmental Microbiology. PMID 29374033 DOI: 10.1128/Aem.02307-17 |
0.319 |
|
| 2017 |
Bennett RK, Gonzalez JE, Whitaker WB, Antoniewicz MR, Papoutsakis ET. Expression of heterologous non-oxidative pentose phosphate pathway from Bacillus methanolicus and phosphoglucose isomerase deletion improves methanol assimilation and metabolite production by a synthetic Escherichia coli methylotroph. Metabolic Engineering. 45: 75-85. PMID 29203223 DOI: 10.1016/J.Ymben.2017.11.016 |
0.351 |
|
| 2017 |
Carlson ED, Papoutsakis ET. Heterologous expression of the Clostridium carboxidivorans CO dehydrogenase alone or together with the acetyl-CoA synthase enables Clostridium acetobutylicum to both reduce CO2 and oxidize CO. Applied and Environmental Microbiology. PMID 28625981 DOI: 10.1128/Aem.00829-17 |
0.311 |
|
| 2017 |
Rohlhill J, Sandoval NR, Papoutsakis ET. Sort-Seq Approach to Engineering a Formaldehyde-Inducible Promoter for Dynamically Regulated Escherichia coli Growth on Methanol. Acs Synthetic Biology. PMID 28463494 DOI: 10.1021/Acssynbio.7B00114 |
0.771 |
|
| 2016 |
Jiang J, Kao CY, Papoutsakis ET. How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells? Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28024915 DOI: 10.1016/J.Jconrel.2016.12.021 |
0.317 |
|
| 2016 |
Whitaker WB, Jones JA, Bennett K, Gonzalez J, Vernacchio VR, Collins SM, Palmer MA, Schmidt S, Antoniewicz MR, Koffas MA, Papoutsakis ET. Engineering the Biological Conversion of Methanol to Specialty Chemicals in Escherichia coli. Metabolic Engineering. PMID 27815193 DOI: 10.1016/J.Ymben.2016.10.015 |
0.303 |
|
| 2016 |
Jones SW, Fast AG, Carlson ED, Wiedel CA, Au J, Antoniewicz MR, Papoutsakis ET, Tracy BP. CO2 fixation by anaerobic non-photosynthetic mixotrophy for improved carbon conversion. Nature Communications. 7: 12800. PMID 27687501 DOI: 10.1038/Ncomms12800 |
0.77 |
|
| 2016 |
Sandoval NR, Papoutsakis ET. Engineering membrane and cell-wall programs for tolerance to toxic chemicals: Beyond solo genes. Current Opinion in Microbiology. 33: 56-66. PMID 27376665 DOI: 10.1016/J.Mib.2016.06.005 |
0.745 |
|
| 2016 |
Lee J, Jang YS, Papoutsakis ET, Lee SY. Stable and Enhanced Gene Expression in Clostridium acetobutylicum Using Synthetic Untranslated Regions with a Stem-Loop. Journal of Biotechnology. PMID 27188957 DOI: 10.1016/J.Jbiotec.2016.05.020 |
0.4 |
|
| 2016 |
Luff SA, Papoutsakis ET. Megakaryocytic Maturation in Response to Shear Flow is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-Activated Protein Kinase (MAPK) Mechanotransduction. The Journal of Biological Chemistry. PMID 26814129 DOI: 10.1074/Jbc.M115.707174 |
0.334 |
|
| 2015 |
Sandoval NR, Venkataramanan KP, Groth TS, Papoutsakis ET. Whole-genome sequence of an evolved Clostridium pasteurianum strain reveals Spo0A deficiency responsible for increased butanol production and superior growth. Biotechnology For Biofuels. 8: 227. PMID 26705421 DOI: 10.1186/S13068-015-0408-7 |
0.764 |
|
| 2015 |
Venkataramanan KP, Min L, Hou S, Jones SW, Ralston MT, Lee KH, Papoutsakis ET. Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum. Biotechnology For Biofuels. 8: 81. PMID 26269711 DOI: 10.1186/S13068-015-0260-9 |
0.732 |
|
| 2015 |
Gaida SM, Sandoval NR, Nicolaou SA, Chen Y, Venkataramanan KP, Papoutsakis ET. Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries. Nature Communications. 6: 7045. PMID 25944046 DOI: 10.1038/Ncomms8045 |
0.8 |
|
| 2015 |
Whitaker WB, Sandoval NR, Bennett RK, Fast AG, Papoutsakis ET. Synthetic methylotrophy: engineering the production of biofuels and chemicals based on the biology of aerobic methanol utilization. Current Opinion in Biotechnology. 33: 165-75. PMID 25796071 DOI: 10.1016/J.Copbio.2015.01.007 |
0.741 |
|
| 2015 |
Al-Hinai MA, Jones SW, Papoutsakis ET. The Clostridium sporulation programs: diversity and preservation of endospore differentiation. Microbiology and Molecular Biology Reviews : Mmbr. 79: 19-37. PMID 25631287 DOI: 10.1128/Mmbr.00025-14 |
0.795 |
|
| 2015 |
Venkataramanan KP, Min L, Hou S, Jones SW, Ralston MT, Lee KH, Papoutsakis ET. Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum Biotechnology For Biofuels. 8. DOI: 10.1186/s13068-015-0260-9 |
0.724 |
|
| 2015 |
Zingaro KA, Papoutsakis ET. Building cellular pathways and programs enabled by the genetic diversity of allo-genomes and meta-genomes Current Opinion in Biotechnology. 36: 16-31. DOI: 10.1016/J.Copbio.2015.08.005 |
0.339 |
|
| 2015 |
Whitaker WB, Sandoval NR, Bennett RK, Fast AG, Papoutsakis ET. Synthetic methylotrophy: Engineering the production of biofuels and chemicals based on the biology of aerobic methanol utilization Current Opinion in Biotechnology. 33: 165-175. DOI: 10.1016/j.copbio.2015.01.007 |
0.7 |
|
| 2014 |
Dash S, Mueller TJ, Venkataramanan KP, Papoutsakis ET, Maranas CD. Capturing the response of Clostridium acetobutylicum to chemical stressors using a regulated genome-scale metabolic model. Biotechnology For Biofuels. 7: 144. PMID 25379054 DOI: 10.1186/S13068-014-0144-4 |
0.356 |
|
| 2014 |
Yuan Y, Bi C, Nicolaou SA, Zingaro KA, Ralston M, Papoutsakis ET. Overexpression of the Lactobacillus plantarum peptidoglycan biosynthesis murA2 gene increases the tolerance of Escherichia coli to alcohols and enhances ethanol production. Applied Microbiology and Biotechnology. 98: 8399-411. PMID 25173692 DOI: 10.1007/S00253-014-6004-0 |
0.797 |
|
| 2014 |
Jiang J, Woulfe DS, Papoutsakis ET. Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells. Blood. 124: 2094-103. PMID 24948658 DOI: 10.1182/Blood-2014-01-547927 |
0.3 |
|
| 2014 |
Zingaro KA, Nicolaou SA, Yuan Y, Papoutsakis ET. Exploring the heterologous genomic space for building, stepwise, complex, multicomponent tolerance to toxic chemicals Acs Synthetic Biology. 3: 476-486. PMID 24933690 DOI: 10.1021/Sb400156V |
0.793 |
|
| 2014 |
Jang YS, Han MJ, Lee J, Im JA, Lee YH, Papoutsakis ET, Bennett G, Lee SY. Proteomic analyses of the phase transition from acidogenesis to solventogenesis using solventogenic and non-solventogenic Clostridium acetobutylicum strains. Applied Microbiology and Biotechnology. 98: 5105-15. PMID 24743985 DOI: 10.1007/S00253-014-5738-Z |
0.338 |
|
| 2014 |
Al-Hinai MA, Jones SW, Papoutsakis ET. σK of Clostridium acetobutylicum is the first known sporulation-specific sigma factor with two developmentally separated roles, one early and one late in sporulation. Journal of Bacteriology. 196: 287-99. PMID 24187083 DOI: 10.1128/Jb.01103-13 |
0.788 |
|
| 2013 |
Venkataramanan KP, Jones SW, McCormick KP, Kunjeti SG, Ralston MT, Meyers BC, Papoutsakis ET. The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. Bmc Genomics. 14: 849. PMID 24299206 DOI: 10.1186/1471-2164-14-849 |
0.743 |
|
| 2013 |
Wang Q, Venkataramanan KP, Huang H, Papoutsakis ET, Wu CH. Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress. Bmc Systems Biology. 7: 120. PMID 24196194 DOI: 10.1186/1752-0509-7-120 |
0.365 |
|
| 2013 |
Zingaro KA, Nicolaou SA, Papoutsakis ET. Dissecting the assays to assess microbial tolerance to toxic chemicals in bioprocessing. Trends in Biotechnology. 31: 643-53. PMID 24094862 DOI: 10.1016/J.Tibtech.2013.08.005 |
0.771 |
|
| 2013 |
Nicolaou SA, Fast AG, Nakamaru-Ogiso E, Papoutsakis ET. Overexpression of fetA (ybbL) and fetB (ybbM), encoding an iron exporter, enhances resistance to oxidative stress in Escherichia coli Applied and Environmental Microbiology. 79: 7210-7219. PMID 24038693 DOI: 10.1128/Aem.02322-13 |
0.768 |
|
| 2013 |
Gaida SM, Al-Hinai MA, Indurthi DC, Nicolaou SA, Papoutsakis ET. Synthetic tolerance: three noncoding small RNAs, DsrA, ArcZ and RprA, acting supra-additively against acid stress. Nucleic Acids Research. 41: 8726-37. PMID 23892399 DOI: 10.1093/Nar/Gkt651 |
0.794 |
|
| 2013 |
Hou S, Jones SW, Choe LH, Papoutsakis ET, Lee KH. Workflow for quantitative proteomic analysis of Clostridium acetobutylicum ATCC 824 using iTRAQ tags. Methods (San Diego, Calif.). 61: 269-76. PMID 23523702 DOI: 10.1016/J.Ymeth.2013.03.013 |
0.739 |
|
| 2013 |
Konieczna IM, Panuganti S, DeLuca TA, Papoutsakis ET, Eklund EA, Miller WM. Administration of nicotinamide does not increase platelet levels in mice. Blood Cells, Molecules & Diseases. 50: 171-6. PMID 23265740 DOI: 10.1016/J.Bcmd.2012.11.007 |
0.782 |
|
| 2013 |
Panuganti S, Schlinker AC, Lindholm PF, Papoutsakis ET, Miller WM. Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production. Tissue Engineering. Part A. 19: 998-1014. PMID 23190353 DOI: 10.1089/Ten.Tea.2011.0111 |
0.792 |
|
| 2013 |
Zingaro KA, Papoutsakis ET. GroESL overexpression imparts Escherichia coli tolerance to i-, n-, and 2-butanol, 1,2,4-butanetriol and ethanol with complex and unpredictable patterns. Metabolic Engineering. 15: 196-205. PMID 22898718 DOI: 10.1016/J.Ymben.2012.07.009 |
0.338 |
|
| 2013 |
Papoutsakis ET, Alsaker KV. Towards a synthetic biology of the stress-response and the tolerance phenotype: Systems understanding and engineering of the clostridium acetobutylicum stress-response and tolerance to toxic metabolites Systems Metabolic Engineering. 193-219. DOI: 10.1007/978-94-007-4534-6_7 |
0.784 |
|
| 2012 |
Zingaro KA, Papoutsakis ET. Toward a semisynthetic stress response system to engineer microbial solvent tolerance Mbio. 3. PMID 23033472 DOI: 10.1128/Mbio.00308-12 |
0.366 |
|
| 2012 |
Al-Hinai MA, Fast AG, Papoutsakis ET. Novel system for efficient isolation of clostridium double-crossover allelic exchange mutants enabling markerless chromosomal gene deletions and DNA integration Applied and Environmental Microbiology. 78: 8112-8121. PMID 22983967 DOI: 10.1128/Aem.02214-12 |
0.803 |
|
| 2012 |
Nicolaou SA, Gaida SM, Papoutsakis ET. Exploring the combinatorial genomic space in Escherichia coli for ethanol tolerance. Biotechnology Journal. 7: 1337-45. PMID 22847918 DOI: 10.1002/Biot.201200227 |
0.773 |
|
| 2012 |
Lindsey S, Papoutsakis ET. The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis. Stem Cell Reviews. 8: 1223-35. PMID 22628113 DOI: 10.1007/S12015-012-9384-5 |
0.327 |
|
| 2012 |
Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation. Physiological Genomics. 44: 638-50. PMID 22548738 DOI: 10.1152/Physiolgenomics.00028.2012 |
0.8 |
|
| 2012 |
Tracy BP, Jones SW, Fast AG, Indurthi DC, Papoutsakis ET. Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications. Current Opinion in Biotechnology. 23: 364-81. PMID 22079352 DOI: 10.1016/J.Copbio.2011.10.008 |
0.786 |
|
| 2012 |
Apostolidis PA, Woulfe DS, Chavez M, Miller WM, Papoutsakis ET. Role of tumor suppressor p53 in megakaryopoiesis and platelet function. Experimental Hematology. 40: 131-42.e4. PMID 22024107 DOI: 10.1016/J.Exphem.2011.10.006 |
0.777 |
|
| 2012 |
Collins PC, Nielsen LK, Wong CK, Papoutsakis ET, Miller WM. Real-time method for determining the colony-forming cell content of human hematopoietic cell cultures. Biotechnology and Bioengineering. 55: 693-700. PMID 18636579 DOI: 10.1002/(Sici)1097-0290(19970820)55:4<693::Aid-Bit11>3.0.Co;2-D |
0.327 |
|
| 2012 |
Cherry RS, Papoutsakis ET. Physical mechanisms of cell damage in microcarrier cell culture bioreactors. Biotechnology and Bioengineering. 32: 1001-14. PMID 18587818 DOI: 10.1002/Bit.260320808 |
0.333 |
|
| 2012 |
Fast AG, Papoutsakis ET. Stoichiometric and energetic analyses of non-photosynthetic CO 2-fixation pathways to support synthetic biology strategies for production of fuels and chemicals Current Opinion in Chemical Engineering. 1: 380-395. DOI: 10.1016/J.Coche.2012.07.005 |
0.328 |
|
| 2011 |
Nicolaou SA, Gaida SM, Papoutsakis ET. Coexisting/Coexpressing Genomic Libraries (CoGeL) identify interactions among distantly located genetic loci for developing complex microbial phenotypes. Nucleic Acids Research. 39: e152. PMID 21976725 DOI: 10.1093/Nar/Gkr817 |
0.792 |
|
| 2011 |
Bi C, Jones SW, Hess DR, Tracy BP, Papoutsakis ET. SpoIIE is necessary for asymmetric division, sporulation, and expression of sigmaF, sigmaE, and sigmaG but does not control solvent production in Clostridium acetobutylicum ATCC 824. Journal of Bacteriology. 193: 5130-7. PMID 21784928 DOI: 10.1128/Jb.05474-11 |
0.804 |
|
| 2011 |
Jones SW, Tracy BP, Gaida SM, Papoutsakis ET. Inactivation of σF in Clostridium acetobutylicum ATCC 824 blocks sporulation prior to asymmetric division and abolishes σE and σG protein expression but does not block solvent formation. Journal of Bacteriology. 193: 2429-40. PMID 21421765 DOI: 10.1128/Jb.00088-11 |
0.813 |
|
| 2011 |
Crown SB, Indurthi DC, Ahn WS, Choi J, Papoutsakis ET, Antoniewicz MR. Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnology Journal. 6: 300-5. PMID 21370473 DOI: 10.1002/Biot.201000282 |
0.371 |
|
| 2011 |
Chen Y, Indurthi DC, Jones SW, Papoutsakis ET. Small RNAs in the genus Clostridium. Mbio. 2: e00340-10. PMID 21264064 DOI: 10.1128/Mbio.00340-10 |
0.743 |
|
| 2011 |
Lindsey S, Papoutsakis ET. The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization. British Journal of Haematology. 152: 469-84. PMID 21226706 DOI: 10.1111/J.1365-2141.2010.08548.X |
0.364 |
|
| 2011 |
Tracy BP, Jones SW, Papoutsakis ET. Inactivation of σE and σG in Clostridium acetobutylicum illuminates their roles in clostridial-cell-form biogenesis, granulose synthesis, solventogenesis, and spore morphogenesis. Journal of Bacteriology. 193: 1414-26. PMID 21217008 DOI: 10.1128/Jb.01380-10 |
0.793 |
|
| 2011 |
Jiang J, Papoutsakis ET. The Importance of Matrix Elasticity and Shear Force on Megakaryocytic Differentiation Blood. 118: 1329-1329. DOI: 10.1182/Blood.V118.21.1329.1329 |
0.353 |
|
| 2011 |
Lindsey SC, Papoutsakis ET. The Aryl Hydrocarbon Receptor Influences Multiple Stages of Megakaryocyte Differentiation Blood. 118: 1298-1298. DOI: 10.1182/Blood.V118.21.1298.1298 |
0.307 |
|
| 2010 |
Sepúlveda DE, Andrews BA, Papoutsakis ET, Asenjo JA. Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns. Biotechnology Progress. 26: 1222-9. PMID 20945480 DOI: 10.1002/Btpr.448 |
0.386 |
|
| 2010 |
Panuganti S, Papoutsakis ET, Miller WM. Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential. Cytotherapy. 12: 767-82. PMID 20482285 DOI: 10.3109/14653241003786148 |
0.786 |
|
| 2010 |
Nicolaou SA, Gaida SM, Papoutsakis ET. A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: From biofuels and chemicals, to biocatalysis and bioremediation. Metabolic Engineering. 12: 307-31. PMID 20346409 DOI: 10.1016/J.Ymben.2010.03.004 |
0.791 |
|
| 2010 |
Tracy BP, Gaida SM, Papoutsakis ET. Flow cytometry for bacteria: enabling metabolic engineering, synthetic biology and the elucidation of complex phenotypes. Current Opinion in Biotechnology. 21: 85-99. PMID 20206495 DOI: 10.1016/J.Copbio.2010.02.006 |
0.779 |
|
| 2010 |
Borden JR, Jones SW, Indurthi D, Chen Y, Papoutsakis ET. A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing. Metabolic Engineering. 12: 268-81. PMID 20060060 DOI: 10.1016/J.Ymben.2009.12.004 |
0.804 |
|
| 2010 |
Alsaker KV, Paredes C, Papoutsakis ET. Metabolite stress and tolerance in the production of biofuels and chemicals: gene-expression-based systems analysis of butanol, butyrate, and acetate stresses in the anaerobe Clostridium acetobutylicum. Biotechnology and Bioengineering. 105: 1131-47. PMID 19998280 DOI: 10.1002/Bit.22628 |
0.807 |
|
| 2010 |
Lee JY, Jang YS, Lee J, Papoutsakis ET, Lee SY. Metabolic engineering of Clostridium acetobutylicum M5 for highly selective butanol production. Biotechnology Journal. 4: 1432-40. PMID 19830716 DOI: 10.1002/Biot.200900142 |
0.348 |
|
| 2010 |
Lindsey SC, Papoutsakis E. Hes1 Expression Impacts Megakaryocytic Polyploidization and May Contribute to the Platelet Defects Found In Aryl Hydrocarbon Receptor (AhR)-Null Mice. Blood. 116: 2612-2612. DOI: 10.1182/Blood.V116.21.2612.2612 |
0.355 |
|
| 2009 |
Giammona LM, Panuganti S, Kemper JM, Apostolidis PA, Lindsey S, Papoutsakis ET, Miller WM. Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. Experimental Hematology. 37: 1340-1352.e3. PMID 19715739 DOI: 10.1016/J.Exphem.2009.08.004 |
0.782 |
|
| 2009 |
Wang M, Senger RS, Paredes C, Banik GG, Lin A, Papoutsakis ET. Microarray-based gene expression analysis as a process characterization tool to establish comparability of complex biological products: scale-up of a whole-cell immunotherapy product. Biotechnology and Bioengineering. 104: 796-808. PMID 19591186 DOI: 10.1002/Bit.22441 |
0.72 |
|
| 2009 |
Sillers R, Al-Hinai MA, Papoutsakis ET. Aldehyde-alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations. Biotechnology and Bioengineering. 102: 38-49. PMID 18726959 DOI: 10.1002/Bit.22058 |
0.787 |
|
| 2009 |
Sandstrom CE, Miller WM, Papoutsakis ET. Serum-free media for cultures of primitive and mature hematopoietic cells. Biotechnology and Bioengineering. 43: 706-33. PMID 18615795 DOI: 10.1002/Bit.260430806 |
0.309 |
|
| 2009 |
Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Thrombopoietin Stimulation Leads to Enhanced Polyploidization in p53-/- Bone Marrow Megakaryocytes: In Vivo and in Vitro Studies. Blood. 114: 2531-2531. DOI: 10.1182/Blood.V114.22.2531.2531 |
0.777 |
|
| 2009 |
Lindsey S, Papoutsakis E. In Megakaryocytic Differentiation, the Aryl Hydrocarbon Receptor (AhR) Transcription Factor Regulates Hes1 Expression and Megakaryocytic Polyploidization. Blood. 114: 2519-2519. DOI: 10.1182/Blood.V114.22.2519.2519 |
0.408 |
|
| 2008 |
Wang M, Windgassen D, Papoutsakis ET. A global transcriptional view of apoptosis in human T-cell activation. Bmc Medical Genomics. 1: 53. PMID 18947405 DOI: 10.1186/1755-8794-1-53 |
0.438 |
|
| 2008 |
Tracy BP, Gaida SM, Papoutsakis ET. Development and application of flow-cytometric techniques for analyzing and sorting endospore-forming clostridia. Applied and Environmental Microbiology. 74: 7497-506. PMID 18931289 DOI: 10.1128/Aem.01626-08 |
0.783 |
|
| 2008 |
Senger RS, Papoutsakis ET. Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis. Biotechnology and Bioengineering. 101: 1036-52. PMID 18767192 DOI: 10.1002/Bit.22010 |
0.654 |
|
| 2008 |
Senger RS, Papoutsakis ET. Genome-scale model for Clostridium acetobutylicum: Part II. Development of specific proton flux states and numerically determined sub-systems. Biotechnology and Bioengineering. 101: 1053-71. PMID 18767191 DOI: 10.1002/Bit.22009 |
0.652 |
|
| 2008 |
Papoutsakis ET. Engineering solventogenic clostridia. Current Opinion in Biotechnology. 19: 420-9. PMID 18760360 DOI: 10.1016/J.Copbio.2008.08.003 |
0.339 |
|
| 2008 |
Sillers R, Chow A, Tracy B, Papoutsakis ET. Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. Metabolic Engineering. 10: 321-32. PMID 18725313 DOI: 10.1016/J.Ymben.2008.07.005 |
0.8 |
|
| 2008 |
Jones SW, Paredes CJ, Tracy B, Cheng N, Sillers R, Senger RS, Papoutsakis ET. The transcriptional program underlying the physiology of clostridial sporulation. Genome Biology. 9: R114. PMID 18631379 DOI: 10.1186/Gb-2008-9-7-R114 |
0.793 |
|
| 2008 |
Wang M, Windgassen D, Papoutsakis ET. Comparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells identifies novel immune response players in T-cell activation. Bmc Genomics. 9: 225. PMID 18485203 DOI: 10.1186/1471-2164-9-225 |
0.401 |
|
| 2008 |
Sepulveda DE, Andrews BA, Asenjo JA, Papoutsakis ET. Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells. Tissue Engineering. Part A. 14: 1603-14. PMID 18433312 DOI: 10.1089/Ten.Tea.2007.0331 |
0.386 |
|
| 2008 |
Fuhrken PG, Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis. The Journal of Biological Chemistry. 283: 15589-600. PMID 18397889 DOI: 10.1074/Jbc.M801923200 |
0.796 |
|
| 2008 |
Fuhrken PG, Chen C, Apostolidis PA, Wang M, Miller WM, Papoutsakis ET. Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis. Physiological Genomics. 33: 159-69. PMID 18252802 DOI: 10.1152/Physiolgenomics.00127.2007 |
0.806 |
|
| 2008 |
Panuganti S, Papoutsakis ET, Miller WM. Nicotinamide increases the megakaryocytic maturation of human hematopoietic stem cells primarily due to sirtuin inhibition Aiche Annual Meeting, Conference Proceedings. DOI: 10.1182/Blood.V112.11.2445.2445 |
0.811 |
|
| 2008 |
Senger RS, Papoutsakis ET. The dynamic biomass constituting equation for the genome-scale model of the biofuels producer clostridium acetobutylicum Aiche Annual Meeting, Conference Proceedings. |
0.59 |
|
| 2007 |
Chen C, Fuhrken PG, Huang LT, Apostolidis P, Wang M, Paredes CJ, Miller WM, Papoutsakis ET. A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis. Bmc Genomics. 8: 384. PMID 17953764 DOI: 10.1186/1471-2164-8-384 |
0.806 |
|
| 2007 |
Thomas R, Paredes CJ, Mehrotra S, Hatzimanikatis V, Papoutsakis ET. A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data. Bmc Bioinformatics. 8: 228. PMID 17603872 DOI: 10.1186/1471-2105-8-228 |
0.333 |
|
| 2007 |
Huang LT, Paredes CJ, Papoutsakis ET, Miller WM. Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes. Physiological Genomics. 31: 114-25. PMID 17550995 DOI: 10.1152/Physiolgenomics.00053.2007 |
0.449 |
|
| 2007 |
Paredes CJ, Senger RS, Spath IS, Borden JR, Sillers R, Papoutsakis ET. A general framework for designing and validating oligomer-based DNA microarrays and its application to Clostridium acetobutylicum. Applied and Environmental Microbiology. 73: 4631-8. PMID 17526797 DOI: 10.1128/Aem.00144-07 |
0.784 |
|
| 2007 |
Pascoe DE, Arnott D, Papoutsakis ET, Miller WM, Andersen DC. Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles. Biotechnology and Bioengineering. 98: 391-410. PMID 17461427 DOI: 10.1002/Bit.21460 |
0.789 |
|
| 2007 |
Wang H, Lu Y, Huang W, Papoutsakis ET, Fuhrken P, Eklund EA. HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells. The Journal of Biological Chemistry. 282: 16164-76. PMID 17430893 DOI: 10.1074/Jbc.M610556200 |
0.817 |
|
| 2007 |
Borden JR, Papoutsakis ET. Dynamics of genomic-library enrichment and identification of solvent tolerance genes for Clostridium acetobutylicum. Applied and Environmental Microbiology. 73: 3061-8. PMID 17337545 DOI: 10.1128/Aem.02296-06 |
0.825 |
|
| 2007 |
Fuhrken PG, Chen C, Miller WM, Papoutsakis ET. Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation. Experimental Hematology. 35: 476-489. PMID 17309828 DOI: 10.1016/J.Exphem.2006.10.017 |
0.831 |
|
| 2007 |
Ramsborg CG, Papoutsakis ET. Global transcriptional analysis delineates the differential inflammatory response interleukin-15 elicits from cultured human T cells. Experimental Hematology. 35: 454-464. PMID 17309826 DOI: 10.1016/J.Exphem.2006.11.013 |
0.786 |
|
| 2007 |
Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K, Heerema NA, Franks R, Tsai SY, Papoutsakis ET, Kiyokawa H. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Research. 67: 984-91. PMID 17283130 DOI: 10.1158/0008-5472.Can-06-3927 |
0.795 |
|
| 2007 |
Sullivan L, Paredes CJ, Papoutsakis ET, Bennett GN. Analysis of the clostridial hydrophobic with a conserved tryptophan family (ChW) of proteins in Clostridium acetobutylicum with emphasis on ChW14 and ChW16/17 Enzyme and Microbial Technology. 42: 29-43. DOI: 10.1016/J.Enzmictec.2007.07.022 |
0.343 |
|
| 2006 |
Giammona LM, Fuhrken PG, Papoutsakis ET, Miller WM. Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes. British Journal of Haematology. 135: 554-66. PMID 17054670 DOI: 10.1111/J.1365-2141.2006.06341.X |
0.8 |
|
| 2006 |
Wang M, Papoutsakis E. Global Transcriptional Analysis Details Prior Knowledge and Identifies New Genes and Processes Associated with T-Cell Activation in the Context of Ex Vivo Expansion. Blood. 108: 1725-1725. DOI: 10.1182/Blood.V108.11.1725.1725 |
0.458 |
|
| 2005 |
Paredes CJ, Alsaker KV, Papoutsakis ET. A comparative genomic view of clostridial sporulation and physiology. Nature Reviews. Microbiology. 3: 969-78. PMID 16261177 DOI: 10.1038/Nrmicro1288 |
0.794 |
|
| 2005 |
Alsaker KV, Papoutsakis ET. Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum. Journal of Bacteriology. 187: 7103-18. PMID 16199581 DOI: 10.1128/Jb.187.20.7103-7118.2005 |
0.821 |
|
| 2005 |
Borden JR, Paredes CJ, Papoutsakis ET. Diffusion, mixing, and associated dye effects in DNA-microarray hybridizations. Biophysical Journal. 89: 3277-84. PMID 16100268 DOI: 10.1529/Biophysj.105.067934 |
0.765 |
|
| 2005 |
Zhao Y, Tomas CA, Rudolph FB, Papoutsakis ET, Bennett GN. Intracellular butyryl phosphate and acetyl phosphate concentrations in Clostridium acetobutylicum and their implications for solvent formation. Applied and Environmental Microbiology. 71: 530-7. PMID 15640230 DOI: 10.1128/Aem.71.1.530-537.2005 |
0.809 |
|
| 2005 |
Miller WM, Huang LT, Chen C, Papoutsakis ET. Developmental Plasticity Revealed by Lineage Switch from Committed Megakaryocytic Cells to Granulocytic Cells. Blood. 106: 3610-3610. DOI: 10.1182/Blood.V106.11.3610.3610 |
0.327 |
|
| 2005 |
Giammona LM, Papoutsakis E, Miller WM. Nicotinamide Enhances the Polyploidization of Primary Megakaryocytes. Blood. 106: 1366-1366. DOI: 10.1182/Blood.V106.11.1366.1366 |
0.8 |
|
| 2005 |
Alsaker KV, Paredes CJ, Papoutsakis ET. Design, optimization and validation of genomic DNA microarrays for examining the Clostridium acetobutylicum transcriptome Biotechnology and Bioprocess Engineering. 10: 432-443. DOI: 10.1007/Bf02989826 |
0.815 |
|
| 2005 |
Papoutsakis ET, Alsaker KV. The transcriptional program of early sporulation and stationary phase events in Clostridium acetobutylicum Aiche Annual Meeting, Conference Proceedings. 11608. |
0.313 |
|
| 2005 |
Fuhrken PG, Miller WM, Papoutsakis ET. Leveraging large-scale transcriptional analysis in cell culture engineering Aiche Annual Meeting, Conference Proceedings. 3494. |
0.345 |
|
| 2004 |
Ramsborg CG, Windgassen D, Fallon JK, Paredes CJ, Papoutsakis ET. Molecular insights into the pleiotropic effects of plasma on ex vivo-expanded T cells using DNA-microarray analysis. Experimental Hematology. 32: 970-90. PMID 15504553 DOI: 10.1016/J.Exphem.2004.07.012 |
0.81 |
|
| 2004 |
Haddad H, Windgassen D, Ramsborg CG, Paredes CJ, Papoutsakis ET. Molecular understanding of oxygen-tension and patient-variability effects on ex vivo expanded T cells. Biotechnology and Bioengineering. 87: 437-50. PMID 15286980 DOI: 10.1002/Bit.20166 |
0.804 |
|
| 2004 |
Thomas R, Mehrotra S, Papoutsakis ET, Hatzimanikatis V. A model-based optimization framework for the inference on gene regulatory networks from DNA array data. Bioinformatics (Oxford, England). 20: 3221-35. PMID 15247105 DOI: 10.1093/Bioinformatics/Bth389 |
0.305 |
|
| 2004 |
Tomas CA, Beamish J, Papoutsakis ET. Transcriptional analysis of butanol stress and tolerance in Clostridium acetobutylicum. Journal of Bacteriology. 186: 2006-18. PMID 15028684 DOI: 10.1128/Jb.186.7.2006-2018.2004 |
0.822 |
|
| 2004 |
Alsaker KV, Spitzer TR, Papoutsakis ET. Transcriptional analysis of spo0A overexpression in Clostridium acetobutylicum and its effect on the cell's response to butanol stress. Journal of Bacteriology. 186: 1959-71. PMID 15028679 DOI: 10.1128/Jb.186.7.1959-1971.2004 |
0.828 |
|
| 2003 |
Tummala SB, Junne SG, Paredes CJ, Papoutsakis ET. Transcriptional analysis of product-concentration driven changes in cellular programs of recombinant Clostridium acetobutylicumstrains. Biotechnology and Bioengineering. 84: 842-54. PMID 14708125 DOI: 10.1002/Bit.10851 |
0.822 |
|
| 2003 |
Tomas CA, Welker NE, Papoutsakis ET. Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program. Applied and Environmental Microbiology. 69: 4951-65. PMID 12902291 DOI: 10.1128/Aem.69.8.4951-4965.2003 |
0.829 |
|
| 2003 |
Tomas CA, Alsaker KV, Bonarius HP, Hendriksen WT, Yang H, Beamish JA, Paredes CJ, Papoutsakis ET. DNA array-based transcriptional analysis of asporogenous, nonsolventogenic Clostridium acetobutylicum strains SKO1 and M5. Journal of Bacteriology. 185: 4539-47. PMID 12867463 DOI: 10.1128/Jb.185.15.4539-4547.2003 |
0.808 |
|
| 2003 |
Tummala SB, Junne SG, Papoutsakis ET. Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde dehydrogenase overexpression leads to predominantly alcohologenic Clostridium acetobutylicum fermentations. Journal of Bacteriology. 185: 3644-53. PMID 12775702 DOI: 10.1128/Jb.185.12.3644-3653.2003 |
0.816 |
|
| 2003 |
Tummala SB, Welker NE, Papoutsakis ET. Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. Journal of Bacteriology. 185: 1923-34. PMID 12618456 DOI: 10.1128/Jb.185.6.1923-1934.2003 |
0.793 |
|
| 2003 |
Yang H, Haddad H, Tomas C, Alsaker K, Papoutsakis ET. A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 1122-7. PMID 12529501 DOI: 10.1073/Pnas.0237337100 |
0.786 |
|
| 2002 |
Yang H, Miller WM, Papoutsakis ET. Higher pH promotes megakaryocytic maturation and apoptosis Stem Cells. 20: 320-328. PMID 12110701 DOI: 10.1634/Stemcells.20-4-320 |
0.317 |
|
| 2002 |
Harris LM, Welker NE, Papoutsakis ET. Northern, morphological, and fermentation analysis of spo0A inactivation and overexpression in Clostridium acetobutylicum ATCC 824. Journal of Bacteriology. 184: 3586-97. PMID 12057953 DOI: 10.1128/Jb.184.13.3586-3597.2002 |
0.666 |
|
| 2002 |
Hevehan DL, Miller WM, Papoutsakis ET. Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation. Blood. 99: 1627-37. PMID 11861277 DOI: 10.1182/Blood.V99.5.1627 |
0.795 |
|
| 2001 |
Haddad H, Papoutsakis ET. Low oxygen tension and autologous plasma enhance T-cell proliferation and CD49d expression density in serum-free media Cytotherapy. 3: 435-447. PMID 11953028 DOI: 10.1080/146532401317248045 |
0.785 |
|
| 2001 |
Harris LM, Blank L, Desai RP, Welker NE, Papoutsakis ET. Fermentation characterization and flux analysis of recombinant strains of Clostridium acetobutylicum with an inactivated solR gene. Journal of Industrial Microbiology & Biotechnology. 27: 322-8. PMID 11781808 DOI: 10.1038/Sj.Jim.7000191 |
0.64 |
|
| 2001 |
Mostafa SS, Papoutsakis ET, Miller WM. Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes. Experimental Hematology. 29: 873-83. PMID 11438210 DOI: 10.1016/S0301-472X(01)00658-0 |
0.788 |
|
| 2001 |
Yang H, Papoutsakis ET, Miller WM. Model-based estimation of myeloid hematopoietic progenitor cells in ex vivo cultures for cell and gene therapies Biotechnology and Bioengineering. 72: 144-155. PMID 11114652 DOI: 10.1002/1097-0290(20000120)72:2<144::Aid-Bit3>3.0.Co;2-4 |
0.359 |
|
| 2000 |
Carswell KS, Weiss JW, Papoutsakis ET. Low oxygen tension enhances the stimulation and proliferation of human T lymphocytes in the presence of IL-2 Cytotherapy. 2: 25-37. PMID 12042052 DOI: 10.1080/146532400539026 |
0.309 |
|
| 2000 |
Patel SD, Miller WM, Winter JN, Papoutsakis ET. Cell density-dependent proliferation in frequently-fed peripheral blood mononuclear cell cultures Cytotherapy. 2: 267-280. PMID 12042036 DOI: 10.1080/146532400539206 |
0.33 |
|
| 2000 |
Carswell KS, Papoutsakis ET. Extracellular pH affects the proliferation of cultured human T cells and their expression of the interleukin-2 receptor Journal of Immunotherapy. 23: 669-674. PMID 11186155 DOI: 10.1097/00002371-200011000-00008 |
0.321 |
|
| 2000 |
Patel SD, Papoutsakis ET, Winter JN, Miller WM. The lactate issue revisited: novel feeding protocols to examine inhibition of cell proliferation and glucose metabolism in hematopoietic cell cultures. Biotechnology Progress. 16: 885-92. PMID 11027185 DOI: 10.1021/Bp000080A |
0.337 |
|
| 2000 |
Hevehan DL, Wenning LA, Miller WM, Papoutsakis ET. Dynamic model of ex vivo granulocytic kinetics to examine the effects of oxygen tension, pH, and interleukin-3. Experimental Hematology. 28: 1016-28. PMID 11008014 DOI: 10.1016/S0301-472X(00)00505-1 |
0.787 |
|
| 2000 |
Carswell KS, Papoutsakis ET. Culture of human T cells in stirred bioreactors for cellular immunotherapy applications: Shear, proliferation, and the IL-2 receptor Biotechnology and Bioengineering. 68: 328-338. PMID 10745201 DOI: 10.1002/(Sici)1097-0290(20000505)68:3<328::Aid-Bit11>3.0.Co;2-V |
0.336 |
|
| 2000 |
Hevehan DL, Papoutsakis ET, Miller WM. Physiologically significant effects of pH and oxygen tension on granulopoiesis Experimental Hematology. 28: 267-275. PMID 10720691 DOI: 10.1016/S0301-472X(99)00150-2 |
0.783 |
|
| 2000 |
Harris LM, Desai RP, Welker NE, Papoutsakis ET. Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: need for new phenomenological models for solventogenesis and butanol inhibition? Biotechnology and Bioengineering. 67: 1-11. PMID 10581430 DOI: 10.1002/(Sici)1097-0290(20000105)67:1<1::Aid-Bit1>3.0.Co;2-G |
0.647 |
|
| 2000 |
Mostafa SS, Miller WM, Papoutsakis ET. Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes British Journal of Haematology. 111: 879-889. DOI: 10.1111/J.1365-2141.2000.02457.X |
0.785 |
|
| 2000 |
Hevehan DL, Wenning LA, Papoutsakis E, Miller WM. A dynamic model of ex vivo granulopoiesis Experimental Hematology. 28: 1498. DOI: 10.1016/S0301-472X(00)00661-5 |
0.789 |
|
| 2000 |
Mostafa S, Papoutsakis E, Miller W. Oxygen tension has significant effects on human megakaryocyte maturation Experimental Hematology. 28: 1498. DOI: 10.1016/S0301-472X(00)00631-7 |
0.302 |
|
| 1999 |
Collins PC, Patel SD, Papoutsakis ET, Miller WM. Nuclei-size distributions as predictive tools of hematopoietic cell proliferation Cytotherapy. 1: 99-110. PMID 19746586 DOI: 10.1080/0032472031000141247 |
0.342 |
|
| 1999 |
Guo M, Miller WM, Papoutsakis ET, Patel S, James C, Goolsby C, Winter JN. Ex-vivo expansion of CFU-GM and BFU-E in unselected PBMC cultures with Flt3L is enhanced by autologous plasma. Cytotherapy. 1: 183-94. PMID 12881174 DOI: 10.1080/14653249910001591266 |
0.308 |
|
| 1999 |
Desai RP, Harris LM, Welker NE, Papoutsakis ET. Metabolic flux analysis elucidates the importance of the acid-formation pathways in regulating solvent production by Clostridium acetobutylicum. Metabolic Engineering. 1: 206-13. PMID 10937935 DOI: 10.1006/Mben.1999.0118 |
0.639 |
|
| 1999 |
Desai RP, Nielsen LK, Papoutsakis ET. Stoichiometric modeling of Clostridium acetobutylicum fermentations with non-linear constraints Journal of Biotechnology. 71: 191-205. PMID 10483106 DOI: 10.1016/S0168-1656(99)00022-X |
0.304 |
|
| 1999 |
Tummala SB, Welker NE, Papoutsakis ET. Development and characterization of a gene expression reporter system for Clostridium acetobutylicum ATCC 824. Applied and Environmental Microbiology. 65: 3793-9. PMID 10473377 DOI: 10.1128/Aem.65.9.3793-3799.1999 |
0.802 |
|
| 1999 |
Desai RP, Papoutsakis ET. Antisense RNA strategies for metabolic engineering of Clostridium acetobutylicum Applied and Environmental Microbiology. 65: 936-945. PMID 10049845 DOI: 10.1128/Aem.65.3.936-945.1999 |
0.36 |
|
| 1999 |
Nair RV, Green EM, Watson DE, Bennett GN, Papoutsakis ET. Regulation of the sol locus genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 by a putative transcriptional repressor. Journal of Bacteriology. 181: 319-30. PMID 9864345 DOI: 10.1128/Jb.181.1.319-330.1999 |
0.435 |
|
| 1999 |
Nair RV, Green EM, Watson DE, Bennett GN, Papoutsakis ET. Regulation of the sol Locus Genes for Butanol and Acetone Formation in Clostridium acetobutylicumATCC 824 by a Putative Transcriptional Repressor Journal of Bacteriology. 181: 319-330. DOI: 10.1128/jb.181.1.319-330.1999 |
0.321 |
|
| 1998 |
Mcadams TA, Miller WM, Papoutsakis ET. pH is a potent modulator of erythroid differentiation British Journal of Haematology. 103: 317-325. PMID 9827900 DOI: 10.1046/J.1365-2141.1998.00975.X |
0.307 |
|
| 1998 |
McDowell CL, Papoutsakis ET. Decreasing extracellular pH increases CD13 receptor surface content and alters the metabolism of HL60 cells cultured in stirred tank bioreactors. Biotechnology Progress. 14: 567-72. PMID 9694677 DOI: 10.1021/Bp980050W |
0.31 |
|
| 1998 |
Bermejo LL, Welker NE, Papoutsakis ET. Expression of Clostridium acetobutylicum ATCC 824 genes in Escherichia coli for acetone production and acetate detoxification Applied and Environmental Microbiology. 64: 1079-1085. PMID 9501448 DOI: 10.1128/Aem.64.3.1079-1085.1998 |
0.402 |
|
| 1997 |
Cornillot E, Nair RV, Papoutsakis ET, Soucaille P. The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain Journal of Bacteriology. 179: 5442-5447. PMID 9286999 DOI: 10.1128/Jb.179.17.5442-5447.1997 |
0.389 |
|
| 1997 |
LaIuppa JA, Papoutsakis ET, Miller WM. Ex vivo expansion of hematopoietic stem and progenitor cells for transplantation Cancer Treatment and Research. 77: 159-186. PMID 9071503 DOI: 10.1007/978-1-4615-6349-5_8 |
0.324 |
|
| 1996 |
Green EM, Boynton ZL, Harris LM, Rudolph FB, Papoutsakis ET, Bennett GN. Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824. Microbiology (Reading, England). 142: 2079-86. PMID 8760920 DOI: 10.1099/13500872-142-8-2079 |
0.637 |
|
| 1996 |
Stim-Herndon K, Nair R, Papoutsakis E, Bennett G. Analysis of Degenerate Variants ofClostridium acetobutylicumATCC 824 Anaerobe. 2: 11-18. DOI: 10.1006/Anae.1996.0002 |
0.358 |
|
| 1995 |
Sandstrom C, Bender J, Papoutsakis E, Miller W. Effects of CD34+ cell selection and perfusion on ex vivo expansion of peripheral blood mononuclear cells Blood. 86: 958-970. DOI: 10.1182/Blood.V86.3.958.Bloodjournal863958 |
0.324 |
|
| 1994 |
Nair RV, Bennett GN, Papoutsakis ET. Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824 Journal of Bacteriology. 176: 871-885. PMID 8300540 DOI: 10.1128/Jb.176.3.871-885.1994 |
0.327 |
|
| 1994 |
Nair RV, Papoutsakis ET. Expression of plasmid-encoded aad in Clostridium acetobutylicum M5 restores vigorous butanol production Journal of Bacteriology. 176: 5843-5846. PMID 8083176 DOI: 10.1128/Jb.176.18.5843-5846.1994 |
0.34 |
|
| 1994 |
Walter KA, Mermelstein LD, Papoutsakis ET. Studies of recombinant clostridium acetobutylicum with increased dosages of butyrate formation genes Annals of the New York Academy of Sciences. 721: 69-72. PMID 8010698 DOI: 10.1111/J.1749-6632.1994.Tb47377.X |
0.366 |
|
| 1994 |
Borys MC, Linzer DI, Papoutsakis ET. Cell aggregation in a Chinese hamster ovary cell microcarrier culture affects the expression rate and N-linked glycosylation of recombinant mouse placental lactogen-1 Annals of the New York Academy of Sciences. 745: 360-371. PMID 7832523 DOI: 10.1111/J.1749-6632.1994.Tb44388.X |
0.344 |
|
| 1994 |
Walter KA, Mermelstein LD, Papoutsakis ET. Host-plasmid interactions in recombinant strains of Clostridium acetobutylicum ATCC 824 Fems Microbiology Letters. 123: 335-341. DOI: 10.1111/J.1574-6968.1994.Tb07245.X |
0.373 |
|
| 1994 |
Papoutsakis ET, Linzer DIH, Borys MC. Culture pH and ammonia affect expression rates and glycosylation of recombinant mouse placental lactogen proteins by CHO cells Animal Cell Technologyproducts of Today, Prospects For Tomorrow. 658-660. DOI: 10.1016/B978-0-7506-1845-8.50149-6 |
0.309 |
|
| 1993 |
Lee SY, Mermelstein LD, Papoutsakis ET. Determination of plasmid copy number and stability in Clostridium acetobutylicum ATCC 824 Fems Microbiology Letters. 108: 319-323. PMID 8514119 DOI: 10.1111/J.1574-6968.1993.Tb06122.X |
0.381 |
|
| 1993 |
Mermelstein LD, Papoutsakis ET. In vivo methylation in Escherichia coli by the Bacillus subtilis phage φ3T I methyltransferase to protect plasmids from restriction upon transformation of Clostridium acetobutylicum ATCC 824 Applied and Environmental Microbiology. 59: 1077-1081. PMID 8386500 DOI: 10.1128/Aem.59.4.1077-1081.1993 |
0.325 |
|
| 1993 |
Walter KA, Nair RV, Cary JW, Bennett GN, Papoutsakis ET. Sequence and arrangement of two genes of the butyrate-synthesis pathway of Clostridium acetobutylicum ATCC 824 Gene. 134: 107-111. PMID 8244020 DOI: 10.1016/0378-1119(93)90182-3 |
0.363 |
|
| 1993 |
Borys MC, Linzer DIH, Papoutsakis ET. Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by chinese hamster ovary (CHO) cells Bio/Technology. 11: 720-724. PMID 7763675 DOI: 10.1038/Nbt0693-720 |
0.353 |
|
| 1993 |
Mermelstein LD, Papoutsakis ET, Petersen DJ, Bennett GN. Metabolic engineering of Clostridium acetobutylicum ATCC 824 for increased solvent production by enhancement of acetone formation enzyme activities using a synthetic acetone operon Biotechnology and Bioengineering. 42: 1053-1060. DOI: 10.1002/Bit.260420906 |
0.367 |
|
| 1992 |
Lee SY, Mermelstein LD, Bennett GN, Papoutsakis ET. Vector construction, transformation, and gene amplification in Clostridium acetobutylicum ATCC 824 Annals of the New York Academy of Sciences. 665: 39-51. PMID 1416617 DOI: 10.1111/J.1749-6632.1992.Tb42572.X |
0.343 |
|
| 1992 |
Walter KA, Bennett GN, Papoutsakis ET. Molecular characterization of two Clostridium acetobutylicum ATCC 824 butanol dehydrogenase isozyme genes Journal of Bacteriology. 174: 7149-7158. PMID 1385386 DOI: 10.1128/Jb.174.22.7149-7158.1992 |
0.361 |
|
| 1992 |
Borys MC, Papoutsakis ET. Formation of bridges and large cellular clumps in CHO-cell microcarrier cultures: Effects of agitation dimethyl sulfoxide and calf serum Cytotechnology. 8: 237-248. PMID 1368821 DOI: 10.1007/Bf02522041 |
0.318 |
|
| 1992 |
MICHAELS JD, KUNAS KT, PAPOUTSAKIS ET. FLUID-MECHANICAL DAMAGE OF FREELY-SUSPENDED ANIMAL CELLS IN AGITATED BIOREACTORS: EFFECTS OF DEXTRAN, DERIVATIZED CELLULOSES AND POLYVINYL ALCOHOL Chemical Engineering Communications. 118: 341-360. DOI: 10.1080/00986449208936102 |
0.313 |
|
| 1992 |
Mermelstein LD, Welker NE, Bennett GN, Papoutsakis ET. Expression of cloned homologous fermentative genes in Clostridium Acetobutylicum ATCC 824 Nature Biotechnology. 10: 190-195. DOI: 10.1038/Nbt0292-190 |
0.383 |
|
| 1992 |
Lakhotia S, Bauer KD, Papoutsakis ET. Damaging agitation intensities increase DNA synthesis rate and alter cell-cycle phase distributions of CHO cells Biotechnology and Bioengineering. 40: 978-990. DOI: 10.1002/Bit.260400814 |
0.334 |
|
| 1992 |
Lakhotia S, Papoutsakis ET. Agitation induced cell injury in microcarrier cultures. Protective effect of viscosity is agitation intensity dependent: Experiments and modeling Biotechnology and Bioengineering. 39: 95-107. DOI: 10.1002/Bit.260390114 |
0.305 |
|
| 1991 |
Petersen DJ, Welch RW, Walter KA, Mermelstein LD, Papoutsakis ET, Rudolph FB, Bennett GN. Cloning of an NADH-dependent butanol dehydrogenase gene from Clostridium acetobutylicum. Annals of the New York Academy of Sciences. 646: 94-8. PMID 1809209 DOI: 10.1111/J.1749-6632.1991.Tb18567.X |
0.354 |
|
| 1991 |
Michaels JD, Papoutsakis ET. Polyvinyl alcohol and polyethylene glycol as protectants against fluid-mechanical injury of freely-suspended animal cells (CRL 8018) Journal of Biotechnology. 19: 241-257. PMID 1367239 DOI: 10.1016/0168-1656(91)90062-Z |
0.304 |
|
| 1990 |
Cary JW, Petersen DJ, Papoutsakis ET, Bennett GN. Cloning and expression of Clostridium acetobutylicum ATCC 824 acetoacetyl-coenzyme A:Acetate/Butyrate:Coenzyme A-transferase in Escherichia coli Applied and Environmental Microbiology. 56: 1576-1583. PMID 2383002 DOI: 10.1128/Aem.56.6.1576-1583.1990 |
0.367 |
|
| 1990 |
Hüsemann MH, Papoutsakis ET. Effects of propionate and acetate additions on solvent production in batch cultures of Clostridium acetobutylicum. Applied and Environmental Microbiology. 56: 1497-500. PMID 2339898 DOI: 10.1128/Aem.56.5.1497-1500.1990 |
0.313 |
|
| 1990 |
Cary JW, Petersen DJ, Bennett GN, Papoutsakis ET. Methods for cloning key primary metabolic enzymes and ancillary proteins associated with the acetone-butanol fermentation of Clostridium acetobutylicum Annals of the New York Academy of Sciences. 589: 67-81. PMID 2192667 DOI: 10.1111/J.1749-6632.1990.Tb24235.X |
0.328 |
|
| 1990 |
Petersen JF, McIntire LV, Papoutsakis ET. Shear sensitivity of hybridoma cells in batch, fed-batch, and continuous cultures Biotechnology Progress. 6: 114-120. PMID 1366545 DOI: 10.1021/Bp00002A004 |
0.342 |
|
| 1989 |
Houston CLM, Papoutsakis ET. Continuous and biomass recycle fermentations of Clostridium acetobutylicum - Part 2: Novel patterns in energetics and product-formation kinetics Bioprocess Engineering. 4: 49-55. DOI: 10.1007/Bf00373731 |
0.31 |
|
| 1989 |
Hüsemann MHW, Papoutsakis ET. Enzymes limiting butanol and acetone formation in continuous and batch cultures of Clostridium acetobutylicum Applied Microbiology and Biotechnology. 31: 435-444. DOI: 10.1007/Bf00270772 |
0.344 |
|
| 1989 |
Hüsemann MHW, Papoutsakis ET. Comparison between in vivo and in vitro enzyme activities in continuous and batch fermentations of Clostridium acetobutylicum Applied Microbiology and Biotechnology. 30: 585-595. DOI: 10.1007/Bf00255364 |
0.342 |
|
| 1988 |
Cary JW, Petersen DJ, Papoutsakis ET, Bennett GN. Cloning and expression of Clostridium acetobutylicum phosphotransbutyrylase and butyrate kinase genes in Escherichia coli Journal of Bacteriology. 170: 4613-4618. PMID 2844725 DOI: 10.1128/Jb.170.10.4613-4618.1988 |
0.385 |
|
| 1987 |
Papoutsakis ET, Bussineau CM, Chu IM, Diwan AR, Huesemann M. TRANSPORT OF SUBSTRATES AND METABOLITES AND THEIR EFFECT ON CELL METABOLISM (IN BUTYRIC-ACID AND METHYLOTROPHIC FERMENTATIONS) Annals of the New York Academy of Sciences. 506: 24-50. PMID 2829684 DOI: 10.1111/J.1749-6632.1987.Tb23808.X |
0.514 |
|
| 1987 |
Chu IM, Keuer TA, Papoutsakis ET. Formate transport, growth inhibition and the membrane protonmotive force in two methylotrophs (T15 and L3) Applied Microbiology and Biotechnology. 26: 70-77. DOI: 10.1007/Bf00282151 |
0.302 |
|
| 1987 |
Bussineau CM, Keuer TA, Chu IM, Papoutsakis ET. Effect of growth conditions on enzyme activities, intracellular kinetics and biomass yields of a new RuMP-type methylotroph (T15) Applied Microbiology and Biotechnology. 26: 61-69. DOI: 10.1007/Bf00282150 |
0.336 |
|
| 1986 |
Huesemann M, Papoutsakis ET. Effect of acetoacetate, butyrate, and uncoupling ionophores on growth and product formation of Clostridium acetobutylicum Biotechnology Letters. 8: 37-42. DOI: 10.1007/Bf01044399 |
0.305 |
|
| 1986 |
Meyer CL, Roos JW, Papoutsakis ET. Carbon monoxide gasing leads to alcohol production and butyrate uptake without acetone formation in continuous cultures of Clostridium acetobutylicum Applied Microbiology and Biotechnology. 24: 159-167. DOI: 10.1007/Bf00250066 |
0.302 |
|
| 1985 |
Meyer CL, McLaughlin JK, Papoutsakis ET. The effect of CO on growth and product formation in batch cultures of Clostridium acetobutylicum Biotechnology Letters. 7: 37-42. DOI: 10.1007/Bf01032417 |
0.305 |
|
| 1982 |
Ramkrishna D, Papoutsakis E. Response to ?comments on the extended Graetz problem with Dirichlet boundary conditions?, by A.S. Jones Applied Scientific Research. 39: 259-259. DOI: 10.1007/Bf00388668 |
0.451 |
|
| 1981 |
Papoutsakis E, Ramkrishna D. Heat Transfer in a Capillary Flow Emerging from a Reservoir Journal of Heat Transfer. 103: 429-435. DOI: 10.1115/1.3244481 |
0.46 |
|
| 1981 |
Papoutsakis E, Lim HC. Single cell protein production on C1 compounds. The bioefficiency Industrial & Engineering Chemistry Fundamentals. 20: 307-314. DOI: 10.1021/i100004a001 |
0.585 |
|
| 1981 |
Papoutsakis E, Ramkrishna D. Conjugated Graetz problems—II Chemical Engineering Science. 36: 1393-1399. DOI: 10.1016/0009-2509(81)80173-X |
0.458 |
|
| 1981 |
Papoutsakis E, Ramkrishna D. Conjugated Graetz problems—I Chemical Engineering Science. 36: 1381-1391. DOI: 10.1016/0009-2509(81)80172-8 |
0.474 |
|
| 1980 |
Papoutsakis E, Ramkrishna D, Lim HC. The extended Graetz problem with Dirichlet wall boundary conditions Applied Scientific Research. 36. DOI: 10.1007/Bf00420067 |
0.667 |
|
| 1980 |
Papoutsakis E, Ramkrishna D, Lim HC. The extended Graetz problem with prescribed wall flux Aiche Journal. 26: 779-787. DOI: 10.1002/Aic.690260511 |
0.465 |
|
| 1978 |
Hirt W, Papoutsakis E, Krug E, Lim HC, Tsao GT. Formaldehyde incorporation by a new methylotroph (L3) Applied and Environmental Microbiology. 36: 56-62. PMID 567956 DOI: 10.1128/Aem.36.1.56-62.1978 |
0.342 |
|
| 1978 |
Papoutsakis E, Lim HC, Tsao GT. Role of formaldehyde in the utilization of C1 compounds via the ribulose monophosphate cycle Biotechnology and Bioengineering. 20: 421-442. DOI: 10.1002/Bit.260200307 |
0.641 |
|
| 1978 |
Papoutsakis E, Lim HC, Tsao GT. SCP production on C1 compounds Aiche Journal. 24: 406-417. DOI: 10.1002/Aic.690240304 |
0.635 |
|
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