cached image

Danesh Moazed - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Website:
https://moazed.med.harvard.edu/

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yuan AH, Moazed D. Minimal requirements for the epigenetic inheritance of engineered silent chromatin domains. Proceedings of the National Academy of Sciences of the United States of America. 121: e2318455121. PMID 38198529 DOI: 10.1073/pnas.2318455121  0.823
2023 Zhou H, Feng W, Yu J, Shafiq TA, Paulo JA, Zhang J, Luo Z, Gygi SP, Moazed D. SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions. Cell Reports. 42: 112339. PMID 37014752 DOI: 10.1016/j.celrep.2023.112339  0.366
2022 Zhou H, Stein CB, Shafiq TA, Shipkovenska G, Kalocsay M, Paulo JA, Zhang J, Luo Z, Gygi SP, Adelman K, Moazed D. Rixosomal RNA degradation contributes to silencing of Polycomb target genes. Nature. 604: 167-174. PMID 35355014 DOI: 10.1038/s41586-022-04598-0  0.433
2021 Wang X, Paulo JA, Li X, Zhou H, Yu J, Gygi SP, Moazed D. A composite DNA element that functions as a maintainer required for epigenetic inheritance of heterochromatin. Molecular Cell. PMID 34375584 DOI: 10.1016/j.molcel.2021.07.017  0.344
2020 Shipkovenska G, Durango A, Kalocsay M, Gygi SP, Moazed D. A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin. Elife. 9. PMID 32491985 DOI: 10.7554/Elife.54341  0.548
2020 Shipkovenska G, Durango A, Kalocsay M, Gygi SP, Moazed D. Author response: A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin Elife. DOI: 10.7554/Elife.54341.Sa2  0.496
2019 Iglesias N, Paulo JA, Tatarakis A, Wang X, Edwards AL, Bhanu NV, Garcia BA, Haas W, Gygi SP, Moazed D. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. Molecular Cell. PMID 31784357 DOI: 10.1016/J.Molcel.2019.10.018  0.488
2018 Iglesias N, Currie MA, Jih G, Paulo JA, Siuti N, Kalocsay M, Gygi SP, Moazed D. Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability. Nature. PMID 30051891 DOI: 10.1038/S41586-018-0398-2  0.484
2018 Yu R, Wang X, Moazed D. Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation. Nature. PMID 29925950 DOI: 10.1038/S41586-018-0239-3  0.505
2017 Iglesias N, Moazed D. Silencing repetitive DNA. Elife. 6. PMID 28760198 DOI: 10.7554/Elife.29503  0.408
2017 Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. PMID 28682306 DOI: 10.1038/Nature23267  0.591
2017 Wang X, Moazed D. DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation. Science (New York, N.Y.). PMID 28302794 DOI: 10.1126/Science.Aaj2114  0.458
2017 Kusevic D, Kudithipudi S, Iglesias N, Moazed D, Jeltsch A. Clr4 specificity and catalytic activity beyond H3K9 methylation. Biochimie. PMID 28143796 DOI: 10.1016/J.Biochi.2017.01.013  0.421
2017 Huang J, Iglesias N, Moazed D. Evaluation of the Nucleolar Localization of the RENT Complex to Ribosomal DNA by Chromatin Immunoprecipitation Assays. Methods in Molecular Biology (Clifton, N.J.). 1505: 195-213. PMID 27826866 DOI: 10.1007/978-1-4939-6502-1_15  0.401
2016 Behrouzi R, Lu C, Currie M, Jih G, Iglesias N, Moazed D. Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes. Elife. 5. PMID 27835568 DOI: 10.7554/Elife.17556  0.521
2016 Jain R, Iglesias N, Moazed D. Distinct Functions of Argonaute Slicer in siRNA Maturation and Heterochromatin Formation. Molecular Cell. PMID 27397687 DOI: 10.1016/J.Molcel.2016.05.039  0.549
2016 Behrouzi R, Lu C, Currie MA, Jih G, Iglesias N, Moazed D. Author response: Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes Elife. DOI: 10.7554/Elife.17556.026  0.32
2015 Martienssen R, Moazed D. RNAi and Heterochromatin Assembly. Cold Spring Harbor Perspectives in Biology. 7. PMID 26238358 DOI: 10.1101/Cshperspect.A019323  0.449
2015 Gerace E, Moazed D. Affinity Pull-Down of Proteins Using Anti-FLAG M2 Agarose Beads. Methods in Enzymology. 559: 99-110. PMID 26096505 DOI: 10.1016/Bs.Mie.2014.11.010  0.772
2015 Gerace E, Moazed D. Affinity Purification of Protein Complexes Using TAP Tags. Methods in Enzymology. 559: 37-52. PMID 26096502 DOI: 10.1016/Bs.Mie.2014.11.007  0.795
2015 Ragunathan K, Jih G, Moazed D. Epigenetics. Epigenetic inheritance uncoupled from sequence-specific recruitment. Science (New York, N.Y.). 348: 1258699. PMID 25831549 DOI: 10.1126/Science.1258699  0.79
2015 Holoch D, Moazed D. Small-RNA loading licenses Argonaute for assembly into a transcriptional silencing complex. Nature Structural & Molecular Biology. 22: 328-35. PMID 25730778 DOI: 10.1038/Nsmb.2979  0.515
2015 Holoch D, Moazed D. RNA-mediated epigenetic regulation of gene expression. Nature Reviews. Genetics. 16: 71-84. PMID 25554358 DOI: 10.1038/Nrg3863  0.525
2014 Egan ED, Braun CR, Gygi SP, Moazed D. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Rna (New York, N.Y.). 20: 867-81. PMID 24713849 DOI: 10.1261/Rna.044479.114  0.552
2014 Gerace E, Moazed D. Coimmunoprecipitation of proteins from yeast. Methods in Enzymology. 541: 13-26. PMID 24674059 DOI: 10.1016/B978-0-12-420119-4.00002-1  0.775
2014 Yu R, Jih G, Iglesias N, Moazed D. Determinants of heterochromatic siRNA biogenesis and function. Molecular Cell. 53: 262-76. PMID 24374313 DOI: 10.1016/J.Molcel.2013.11.014  0.534
2013 Johnson A, Wu R, Peetz M, Gygi SP, Moazed D. Heterochromatic gene silencing by activator interference and a transcription elongation barrier. The Journal of Biological Chemistry. 288: 28771-82. PMID 23940036 DOI: 10.1074/Jbc.M113.460071  0.661
2013 Moazed D. Chromatin: a tail of repression. Current Biology : Cb. 23: R456-9. PMID 23701691 DOI: 10.1016/J.Cub.2013.04.033  0.39
2013 Wang F, Li G, Altaf M, Lu C, Currie MA, Johnson A, Moazed D. Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proceedings of the National Academy of Sciences of the United States of America. 110: 8495-500. PMID 23650358 DOI: 10.1073/Pnas.1300126110  0.671
2012 Moazed D. A piRNA to remember. Cell. 149: 512-4. PMID 22541425 DOI: 10.1016/J.Cell.2012.04.008  0.356
2012 Holoch D, Moazed D. RNAi in fission yeast finds new targets and new ways of targeting at the nuclear periphery. Genes & Development. 26: 741-5. PMID 22508721 DOI: 10.1101/Gad.191155.112  0.427
2012 Tung SY, Hong JY, Walz T, Moazed D, Liou GG. Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose. Cellular and Molecular Life Sciences : Cmls. 69: 641-50. PMID 21796450 DOI: 10.1007/S00018-011-0771-X  0.396
2011 Moazed D. Mechanisms for the inheritance of chromatin states. Cell. 146: 510-8. PMID 21854979 DOI: 10.1016/J.Cell.2011.07.013  0.481
2011 Gullerova M, Moazed D, Proudfoot NJ. Autoregulation of convergent RNAi genes in fission yeast. Genes & Development. 25: 556-68. PMID 21357674 DOI: 10.1101/Gad.618611  0.364
2010 Gerace EL, Moazed D. Histone demethylation and timely DNA replication. Molecular Cell. 40: 683-4. PMID 21145476 DOI: 10.1016/J.Molcel.2010.11.036  0.807
2010 Gerace EL, Halic M, Moazed D. The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation. Molecular Cell. 39: 360-72. PMID 20705239 DOI: 10.1016/J.Molcel.2010.07.017  0.847
2010 Mekhail K, Moazed D. The nuclear envelope in genome organization, expression and stability. Nature Reviews. Molecular Cell Biology. 11: 317-28. PMID 20414256 DOI: 10.1038/Nrm2894  0.701
2010 Halic M, Moazed D. Dicer-independent primal RNAs trigger RNAi and heterochromatin formation. Cell. 140: 504-16. PMID 20178743 DOI: 10.1016/J.Cell.2010.01.019  0.499
2009 Moazed D. Molecular biology. Rejoice--RNAi for yeast. Science (New York, N.Y.). 326: 533-4. PMID 19900888 DOI: 10.1126/Science.1182102  0.521
2009 Halic M, Moazed D. 22G-RNAs in transposon silencing and centromere function. Molecular Cell. 36: 170-1. PMID 19854125 DOI: 10.1016/J.Molcel.2009.10.010  0.323
2009 Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Molecular Cell. 35: 769-81. PMID 19782027 DOI: 10.1016/J.Molcel.2009.07.030  0.724
2009 Sinha M, Watanabe S, Johnson A, Moazed D, Peterson CL. Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell. 138: 1109-21. PMID 19766565 DOI: 10.1016/J.Cell.2009.07.013  0.579
2009 Halic M, Moazed D. Transposon silencing by piRNAs. Cell. 138: 1058-60. PMID 19766558 DOI: 10.1016/J.Cell.2009.08.030  0.39
2009 Li H, Motamedi MR, Yip CK, Wang Z, Walz T, Patel DJ, Moazed D. An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Molecular Cell. 34: 155-67. PMID 19394293 DOI: 10.1016/J.Molcel.2009.02.032  0.695
2009 Tomson BN, Rahal R, Reiser V, Monje-Casas F, Mekhail K, Moazed D, Amon A. Regulation of Spo12 phosphorylation and its essential role in the FEAR network. Current Biology : Cb. 19: 449-60. PMID 19268588 DOI: 10.1016/J.Cub.2009.02.024  0.654
2009 Moazed D. Small RNAs in transcriptional gene silencing and genome defence. Nature. 457: 413-20. PMID 19158787 DOI: 10.1038/Nature07756  0.53
2008 Motamedi MR, Hong EJ, Li X, Gerber S, Denison C, Gygi S, Moazed D. HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. Molecular Cell. 32: 778-90. PMID 19111658 DOI: 10.1016/J.Molcel.2008.10.026  0.731
2008 Mekhail K, Seebacher J, Gygi SP, Moazed D. Role for perinuclear chromosome tethering in maintenance of genome stability. Nature. 456: 667-70. PMID 18997772 DOI: 10.1038/Nature07460  0.744
2008 Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K. Epigenomics: a roadmap, but to where? Science (New York, N.Y.). 322: 43-4. PMID 18832628 DOI: 10.1126/Science.322.5898.43B  0.384
2008 Buchberger JR, Onishi M, Li G, Seebacher J, Rudner AD, Gygi SP, Moazed D. Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae. Molecular and Cellular Biology. 28: 6903-18. PMID 18794362 DOI: 10.1128/Mcb.01210-08  0.789
2008 Bühler M, Spies N, Bartel DP, Moazed D. TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway. Nature Structural & Molecular Biology. 15: 1015-23. PMID 18776903 DOI: 10.1038/Nsmb.1481  0.672
2008 Iida T, Nakayama J, Moazed D. siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription. Molecular Cell. 31: 178-89. PMID 18657501 DOI: 10.1016/J.Molcel.2008.07.003  0.555
2008 Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine JC, de Cabo R, Cohen HY. Regulation of SIRT6 protein levels by nutrient availability. Febs Letters. 582: 543-8. PMID 18242175 DOI: 10.1016/J.Febslet.2008.01.019  0.32
2007 Onishi M, Liou GG, Buchberger JR, Walz T, Moazed D. Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly. Molecular Cell. 28: 1015-28. PMID 18158899 DOI: 10.1016/J.Molcel.2007.12.004  0.8
2007 Bühler M, Moazed D. Transcription and RNAi in heterochromatic gene silencing. Nature Structural & Molecular Biology. 14: 1041-8. PMID 17984966 DOI: 10.1038/Nsmb1315  0.7
2007 Colmenares SU, Buker SM, Buhler M, Dlaki? M, Moazed D. Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi. Molecular Cell. 27: 449-61. PMID 17658285 DOI: 10.1016/J.Molcel.2007.07.007  0.799
2007 Skiniotis G, Moazed D, Walz T. Acetylated histone tail peptides induce structural rearrangements in the RSC chromatin remodeling complex. The Journal of Biological Chemistry. 282: 20804-8. PMID 17535815 DOI: 10.1074/Jbc.C700081200  0.471
2007 Niu H, Li X, Job E, Park C, Moazed D, Gygi SP, Hollingsworth NM. Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis. Molecular and Cellular Biology. 27: 5456-67. PMID 17526735 DOI: 10.1128/Mcb.00416-07  0.351
2007 Bühler M, Haas W, Gygi SP, Moazed D. RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing. Cell. 129: 707-21. PMID 17512405 DOI: 10.1016/J.Cell.2007.03.038  0.711
2007 Lan F, Zaratiegui M, Villén J, Vaughn MW, Verdel A, Huarte M, Shi Y, Gygi SP, Moazed D, Martienssen RA, Shi Y. S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Molecular Cell. 26: 89-101. PMID 17434129 DOI: 10.1016/J.Molcel.2007.02.023  0.727
2007 Morris CA, Moazed D. Centromere assembly and propagation. Cell. 128: 647-50. PMID 17320502 DOI: 10.1016/J.Cell.2007.02.002  0.622
2007 Buker SM, Iida T, Bühler M, Villén J, Gygi SP, Nakayama J, Moazed D. Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast. Nature Structural & Molecular Biology. 14: 200-7. PMID 17310250 DOI: 10.1038/Nsmb1211  0.849
2006 Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP. Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harbor Symposia On Quantitative Biology. 71: 461-71. PMID 17381328 DOI: 10.1101/Sqb.2006.71.044  0.799
2006 Huang J, Brito IL, Villén J, Gygi SP, Amon A, Moazed D. Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. Genes & Development. 20: 2887-901. PMID 17043313 DOI: 10.1101/Gad.1472706  0.484
2006 Matecic M, Martins-Taylor K, Hickman M, Tanny J, Moazed D, Holmes SG. New alleles of SIR2 define cell-cycle-specific silencing functions. Genetics. 173: 1939-50. PMID 16783021 DOI: 10.1534/Genetics.106.055491  0.641
2006 Bühler M, Verdel A, Moazed D. Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing. Cell. 125: 873-86. PMID 16751098 DOI: 10.1016/J.Cell.2006.04.025  0.832
2006 Huang J, Moazed D. Sister chromatid cohesion in silent chromatin: each sister to her own ring. Genes & Development. 20: 132-7. PMID 16418479 DOI: 10.1101/Gad.1398106  0.34
2005 Hong EJ, Villén J, Gerace EL, Gygi SP, Moazed D. A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation. Rna Biology. 2: 106-11. PMID 17114925 DOI: 10.4161/Rna.2.3.2131  0.855
2005 Verdel A, Moazed D. RNAi-directed assembly of heterochromatin in fission yeast. Febs Letters. 579: 5872-8. PMID 16223485 DOI: 10.1016/J.Febslet.2005.08.083  0.778
2005 Buratowski S, Moazed D. Gene regulation: expression and silencing coupled. Nature. 435: 1174-5. PMID 15988510 DOI: 10.1038/4351174B  0.355
2005 Liou GG, Tanny JC, Kruger RG, Walz T, Moazed D. Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell. 121: 515-27. PMID 15907466 DOI: 10.1016/J.Cell.2005.03.035  0.722
2005 Rudner AD, Hall BE, Ellenberger T, Moazed D. A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin. Molecular and Cellular Biology. 25: 4514-28. PMID 15899856 DOI: 10.1128/Mcb.25.11.4514-4528.2005  0.815
2005 Verdel A, Moazed D. Labeling and characterization of small RNAs associated with the RNA interference effector complex RITS. Methods in Enzymology. 392: 297-307. PMID 15644188 DOI: 10.1016/S0076-6879(04)92017-4  0.736
2005 Sugiyama T, Cam H, Verdel A, Moazed D, Grewal SI. RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production. Proceedings of the National Academy of Sciences of the United States of America. 102: 152-7. PMID 15615848 DOI: 10.1073/Pnas.0407641102  0.745
2005 Denison C, Rudner AD, Gerber SA, Bakalarski CE, Moazed D, Gygi SP. A proteomic strategy for gaining insights into protein sumoylation in yeast. Molecular & Cellular Proteomics : McP. 4: 246-54. PMID 15542864 DOI: 10.1074/Mcp.M400154-Mcp200  0.74
2004 Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell. 119: 789-802. PMID 15607976 DOI: 10.1016/J.Cell.2004.11.034  0.824
2004 Noma K, Sugiyama T, Cam H, Verdel A, Zofall M, Jia S, Moazed D, Grewal SI. RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nature Genetics. 36: 1174-80. PMID 15475954 DOI: 10.1038/Ng1452  0.771
2004 Tanny JC, Kirkpatrick DS, Gerber SA, Gygi SP, Moazed D. Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions. Molecular and Cellular Biology. 24: 6931-46. PMID 15282295 DOI: 10.1128/Mcb.24.16.6931-6946.2004  0.724
2004 Moazed D, Rudner AD, Huang J, Hoppe GJ, Tanny JC. A model for step-wise assembly of heterochromatin in yeast. Novartis Foundation Symposium. 259: 48-56; discussion 56. PMID 15171246 DOI: 10.1002/0470862637.Ch4  0.849
2004 Stegmeier F, Huang J, Rahal R, Zmolik J, Moazed D, Amon A. The replication fork block protein Fob1 functions as a negative regulator of the FEAR network. Current Biology : Cb. 14: 467-80. PMID 15043811 DOI: 10.1016/J.Cub.2004.03.009  0.342
2004 Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D. RNAi-mediated targeting of heterochromatin by the RITS complex. Science (New York, N.Y.). 303: 672-6. PMID 14704433 DOI: 10.1126/Science.1093686  0.775
2004 Chang JF, Hall BE, Tanny JC, Moazed D, Filman D, Ellenberger T. Erratum: Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3 (Structure 11 (637-649)) Structure. 12. DOI: 10.1016/J.Str.2004.07.005  0.584
2003 Huang J, Moazed D. Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing. Genes & Development. 17: 2162-76. PMID 12923057 DOI: 10.1101/Gad.1108403  0.51
2003 Grewal SI, Moazed D. Heterochromatin and epigenetic control of gene expression. Science (New York, N.Y.). 301: 798-802. PMID 12907790 DOI: 10.1126/Science.1086887  0.536
2003 Shankaranarayana GD, Motamedi MR, Moazed D, Grewal SI. Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast. Current Biology : Cb. 13: 1240-6. PMID 12867036 DOI: 10.1016/S0960-9822(03)00489-5  0.672
2003 Chang JF, Hall BE, Tanny JC, Moazed D, Filman D, Ellenberger T. Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3. Structure (London, England : 1993). 11: 637-49. PMID 12791253 DOI: 10.1016/S0969-2126(03)00093-5  0.71
2002 Li J, Moazed D, Gygi SP. Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation. The Journal of Biological Chemistry. 277: 49383-8. PMID 12381723 DOI: 10.1074/Jbc.M209294200  0.496
2002 Tanny JC, Moazed D. Recognition of acetylated proteins: lessons from an ancient family of enzymes. Structure (London, England : 1993). 10: 1290-2. PMID 12377115 DOI: 10.1016/S0969-2126(02)00862-6  0.592
2002 Kellogg DR, Moazed D. Protein- and immunoaffinity purification of multiprotein complexes. Methods in Enzymology. 351: 172-83. PMID 12073344 DOI: 10.1016/S0076-6879(02)51847-4  0.374
2002 Hoppe GJ, Tanny JC, Rudner AD, Gerber SA, Danaie S, Gygi SP, Moazed D. Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Molecular and Cellular Biology. 22: 4167-80. PMID 12024030 DOI: 10.1128/Mcb.22.12.4167-4180.2002  0.849
2001 Moazed D. Common themes in mechanisms of gene silencing. Molecular Cell. 8: 489-98. PMID 11583612 DOI: 10.1016/S1097-2765(01)00340-9  0.559
2001 Shou W, Sakamoto KM, Keener J, Morimoto KW, Traverso EE, Azzam R, Hoppe GJ, Feldman RM, DeModena J, Moazed D, Charbonneau H, Nomura M, Deshaies RJ. Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. Molecular Cell. 8: 45-55. PMID 11511359 DOI: 10.1016/S1097-2765(01)00291-X  0.461
2001 Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. The Journal of Biological Chemistry. 276: 38837-43. PMID 11483616 DOI: 10.1074/Jbc.M106779200  0.35
2001 Moazed D. Enzymatic activities of Sir2 and chromatin silencing. Current Opinion in Cell Biology. 13: 232-8. PMID 11248558 DOI: 10.1016/S0955-0674(00)00202-7  0.486
2001 Tanny JC, Moazed D. Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product. Proceedings of the National Academy of Sciences of the United States of America. 98: 415-20. PMID 11134535 DOI: 10.1073/Pnas.98.2.415  0.658
1999 Tanny JC, Dowd GJ, Huang J, Hilz H, Moazed D. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell. 99: 735-45. PMID 10619427 DOI: 10.1016/S0092-8674(00)81671-2  0.701
1999 Straight AF, Shou W, Dowd GJ, Turck CW, Deshaies RJ, Johnson AD, Moazed D. Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell. 97: 245-56. PMID 10219245 DOI: 10.1016/S0092-8674(00)80734-5  0.724
1999 Shou W, Seol JH, Shevchenko A, Baskerville C, Moazed D, Chen ZW, Jang J, Shevchenko A, Charbonneau H, Deshaies RJ. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell. 97: 233-44. PMID 10219244 DOI: 10.1016/S0092-8674(00)80733-3  0.437
1999 Merryman C, Moazed D, Daubresse G, Noller HF. Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunits. Journal of Molecular Biology. 285: 107-13. PMID 9878392 DOI: 10.1006/Jmbi.1998.2243  0.569
1999 Merryman C, Moazed D, McWhirter J, Noller HF. Nucleotides in 16S rRNA protected by the association of 30S and 50S ribosomal subunits. Journal of Molecular Biology. 285: 97-105. PMID 9878391 DOI: 10.1006/Jmbi.1998.2242  0.567
1997 Moazed D, Kistler A, Axelrod A, Rine J, Johnson AD. Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proceedings of the National Academy of Sciences of the United States of America. 94: 2186-91. PMID 9122169 DOI: 10.1073/Pnas.94.6.2186  0.682
1996 Moazed D, Johnson D. A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae. Cell. 86: 667-77. PMID 8752220 DOI: 10.1016/S0092-8674(00)80139-7  0.467
1995 Moazed D, Samaha RR, Gualerzi C, Noller HF. Specific protection of 16 S rRNA by translational initiation factors. Journal of Molecular Biology. 248: 207-10. PMID 7739034 DOI: 10.1016/S0022-2836(95)80042-5  0.553
1992 Moazed D, O'Farrell PH. Maintenance of the engrailed expression pattern by Polycomb group genes in Drosophila. Development (Cambridge, England). 116: 805-10. PMID 1363229  0.455
1991 Moazed D, Noller HF. Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA. Proceedings of the National Academy of Sciences of the United States of America. 88: 3725-8. PMID 2023922 DOI: 10.1073/Pnas.88.9.3725  0.543
1991 Woodcock J, Moazed D, Cannon M, Davies J, Noller HF. Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA. The Embo Journal. 10: 3099-103. PMID 1915283 DOI: 10.1002/J.1460-2075.1991.Tb07863.X  0.537
1990 Moazed D, Noller HF. Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA. Journal of Molecular Biology. 211: 135-45. PMID 2405162 DOI: 10.1016/0022-2836(90)90016-F  0.529
1989 Moazed D, Noller HF. Intermediate states in the movement of transfer RNA in the ribosome. Nature. 342: 142-8. PMID 2682263 DOI: 10.1038/342142A0  0.618
1989 De Stasio EA, Moazed D, Noller HF, Dahlberg AE. Mutations in 16S ribosomal RNA disrupt antibiotic--RNA interactions. The Embo Journal. 8: 1213-6. PMID 2472961 DOI: 10.1002/J.1460-2075.1989.Tb03494.X  0.582
1989 Moazed D, Noller HF. Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites. Cell. 57: 585-97. PMID 2470511 DOI: 10.1016/0092-8674(89)90128-1  0.581
1988 Stern S, Moazed D, Noller HF. Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension. Methods in Enzymology. 164: 481-9. PMID 2468070 DOI: 10.1016/S0076-6879(88)64064-X  0.598
1988 Moazed D, Robertson JM, Noller HF. Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. Nature. 334: 362-4. PMID 2455872 DOI: 10.1038/334362A0  0.647
1987 Noller HF, Stern S, Moazed D, Powers T, Svensson P, Changchien LM. Studies on the architecture and function of 16S rRNA. Cold Spring Harbor Symposia On Quantitative Biology. 52: 695-708. PMID 3454283 DOI: 10.1101/Sqb.1987.052.01.079  0.485
1987 Moazed D, Noller HF. Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie. 69: 879-84. PMID 3122849 DOI: 10.1016/0300-9084(87)90215-X  0.58
1987 Moazed D, Noller HF. Interaction of antibiotics with functional sites in 16S ribosomal RNA. Nature. 327: 389-94. PMID 2953976 DOI: 10.1038/327389A0  0.606
1986 Moazed D, Van Stolk BJ, Douthwaite S, Noller HF. Interconversion of active and inactive 30 S ribosomal subunits is accompanied by a conformational change in the decoding region of 16 S rRNA. Journal of Molecular Biology. 191: 483-93. PMID 2434656 DOI: 10.1016/0022-2836(86)90143-9  0.548
1986 Moazed D, Noller HF. Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes. Cell. 47: 985-94. PMID 2430725 DOI: 10.1016/0092-8674(86)90813-5  0.535
1986 Moazed D, Stern S, Noller HF. Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extension. Journal of Molecular Biology. 187: 399-416. PMID 2422386 DOI: 10.1016/0022-2836(86)90441-9  0.588
1985 Noller HF, Van Stolk BJ, Moazed D, Douthwaite S, Gutell RR. Studies on the structure and function of 16S ribosomal RNA using structure-specific chemical probes Journal of Biosciences. 8: 747-755. DOI: 10.1007/Bf02702773  0.608
Show low-probability matches.