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Jeffery M. Klco, Ph.D. - Publications

Affiliations: 
2007 Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology
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56/127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Michmerhuizen NL, Klco JM, Mullighan CG. Mechanistic insights and potential therapeutic targets for NUP98-rearranged hematologic malignancies. Blood. PMID 32766874 DOI: 10.1182/Blood.2020007093  0.322
2020 Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, Hoshitsuki K, Bloom M, Verbist KC, Burns MA, Li Z, Lin TN, Qian M, Moriyama T, Gastier-Foster JM, ... ... Klco JM, et al. Molecular Basis of ETV6-Mediated Predisposition to Childhood Acute Lymphoblastic Leukemia. Blood. PMID 32693409 DOI: 10.1182/Blood.2020006164  0.379
2020 Schwartz JR, Connelly JP, Pruett-Miller SM, Klco JM. Abstract B49: Modeling a pathogenic SAMD9 mutation in human induced pluripotent stem cells Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B49  0.359
2020 Hiltenbrand R, Miller J, Klco J. Abstract B34: Cord blood CD34+ HSPCs: An in vitro model system for characterizing NUP98 fusions Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B34  0.339
2020 Lamprecht T, Schwartz JR, Ma J, Walsh MP, Klco JM. Abstract B16: MECOM dysregulation is associated with poor outcome in pediatric therapy-related myeloid neoplasms Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B16  0.332
2019 Elsayed AH, Rafiee R, Cao X, Raimondi S, Downing JR, Ribeiro R, Fan Y, Gruber TA, Baker S, Klco J, Rubnitz JE, Pounds S, Lamba JK. A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia. Leukemia. PMID 31645648 DOI: 10.1038/S41375-019-0604-8  0.313
2019 Miller J, Hiltenbrand R, Lamprecht T, Seth A, Abdelhamed S, Iacobucci I, Mullighan CG, Klco JM. NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation Blood. 134: 3775-3775. DOI: 10.1182/Blood-2019-130768  0.357
2019 Schwartz JR, Ma J, Walsh MP, Chen X, Lamprecht T, Kamens J, Newman S, Zhang J, Gruber TA, Ma X, Klco JM. Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome Blood. 134: 1394-1394. DOI: 10.1182/Blood-2019-128665  0.372
2019 Gruber TA, Ma J, Noort S, Liu Y, Walsh MP, Nance S, Liu Y, Wang Y, Song G, Lamprecht T, Easton J, Pigazzi M, Jarosova M, Charikleia K, Rubnitz J, ... ... Klco JM, et al. Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses Blood. 134: 918-918. DOI: 10.1182/Blood-2019-127411  0.405
2019 Schwartz JR, Wlodarski MW, Klco JM. Role of Genetic Evolution and Germline Mutations in SAMD9 and SAMD9L Genes Blood. 134: SCI-33-SCI-33. DOI: 10.1182/Blood-2019-121042  0.374
2018 Galera P, Hsu AP, Wang W, Droll S, Chen R, Schwartz JR, Klco JM, Arai S, Maese L, Zerbe C, Parta MJ, Young NS, Holland SM, Hickstein DD, Calvo KR. Donor-derived MDS/AML in families with germline GATA2 mutation. Blood. PMID 30232126 DOI: 10.1182/Blood-2018-07-861070  0.345
2018 Wong JC, Bryant V, Lamprecht T, Ma J, Walsh M, Schwartz J, Del Pilar Alzamora M, Mullighan CG, Loh ML, Ribeiro R, Downing JR, Carroll WL, Davis J, Gold S, Rogers PC, ... ... Klco JM, et al. Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes. Jci Insight. 3. PMID 30046003 DOI: 10.1172/Jci.Insight.121086  0.361
2018 Malireddi RKS, Gurung P, Mavuluri J, Dasari TK, Klco JM, Chi H, Kanneganti TD. TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation. The Journal of Experimental Medicine. PMID 29500178 DOI: 10.1084/Jem.20171922  0.302
2018 Ortolano R, Parekh DS, Rosen BJ, Bryant V, Chen D, Klco JM, Raskind WH, Lieuw K. Novel V1551L Mutation in SAMD9L Inhibits Cell Cycle Progression and Results in Pancytopenia That Progresses to MDS with Monosomy 7 Blood. 132: 3863-3863. DOI: 10.1182/Blood-2018-99-120250  0.38
2018 Schwartz JR, Walsh MP, Ma J, Lamprecht T, Ribeiro RC, Klco JM. The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms Blood. 132: 2775-2775. DOI: 10.1182/Blood-2018-99-118995  0.371
2018 Bryant V, Wong J, Schwartz J, Lamprecht T, Ma J, Mullighan C, Loh M, Shannon K, Klco J. Abstract 2063: SAMD9/SAMD9L mutations in familial monosomy 7 Cancer Research. 78: 2063-2063. DOI: 10.1158/1538-7445.Am2018-2063  0.347
2017 Schwartz JR, Ma J, Lamprecht T, Walsh M, Wang S, Bryant V, Song G, Wu G, Easton J, Kesserwan C, Nichols KE, Mullighan CG, Ribeiro RC, Klco JM. The genomic landscape of pediatric myelodysplastic syndromes. Nature Communications. 8: 1557. PMID 29146900 DOI: 10.1038/S41467-017-01590-5  0.345
2017 Cole CB, Russler-Germain DA, Ketkar S, Verdoni AM, Smith AM, Bangert CV, Helton NM, Guo M, Klco JM, O'Laughlin S, Fronick C, Fulton R, Chang GS, Petti AA, Miller CA, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. The Journal of Clinical Investigation. PMID 28872462 DOI: 10.1172/Jci93041  0.367
2016 Faber ZJ, Chen X, Gedman AL, Boggs K, Cheng J, Ma J, Radtke I, Chao JR, Walsh MP, Song G, Andersson AK, Dang J, Dong L, Liu Y, Huether R, ... ... Klco JM, et al. The genomic landscape of core-binding factor acute myeloid leukemias. Nature Genetics. PMID 27798625 DOI: 10.1038/Ng.3709  0.375
2016 Drenberg CD, Buelow DR, Pounds SB, Wang YD, Finkelstein D, Rahija RJ, Shurtleff SA, Rubnitz JE, Inaba H, Gruber TA, Klco JM, Baker SD. Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation. Leukemia & Lymphoma. 1-4. PMID 27248844 DOI: 10.1080/10428194.2016.1187272  0.34
2016 Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, et al. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology. PMID 27181063 DOI: 10.1016/J.Exphem.2016.04.011  0.35
2015 Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, et al. Rapid expansion of pre-existing non-leukemic hematopoietic clones frequently follows induction therapy for de novo AML. Blood. PMID 26631115 DOI: 10.1182/Blood-2015-10-677021  0.361
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, et al. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. Jama. 314: 811-22. PMID 26305651 DOI: 10.1001/Jama.2015.9643  0.31
2015 Li C, Klco JM, Helton NM, George DR, Mudd JL, Miller CA, Lu C, Fulton R, O'Laughlin M, Fronick C, Wilson RK, Ley TJ. Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse. Plos One. 10: e0120585. PMID 25799070 DOI: 10.1371/Journal.Pone.0120585  0.304
2015 Spencer DH, Young MA, Lamprecht TL, Helton NM, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Miller CA, Klco JM, Wilson RK, Ley TJ. Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells. Leukemia. 29: 1279-89. PMID 25600023 DOI: 10.1038/Leu.2015.6  0.323
2015 Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/Nature13968  0.344
2015 Celik H, Mallaney C, Kothari A, Ostrander EL, Eultgen E, Martens A, Miller CA, Hundal J, Klco JM, Challen GA. Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation. Blood. 125: 619-28. PMID 25416276 DOI: 10.1182/Blood-2014-08-594564  0.351
2015 Wong TN, Klco JM, Demeter R, Miller CA, Petti A, Havey N, Fulton R, Heath S, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert T, Wilson RK, et al. Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Cytoreductive Chemotherapy in Adult De Novo AML Patients Blood. 126: 686-686. DOI: 10.1182/Blood.V126.23.686.686  0.376
2015 Verdoni AM, Venezia C, Klco J, Ley TJ. DNMT3A R882H Can Cooperate with FLT3-ITD to Cause AML in Mice Blood. 126: 2458-2458. DOI: 10.1182/Blood.V126.23.2458.2458  0.33
2015 Spencer D, George DR, Klco JM, Ley TJ. Reprogramming of Leukemic and Pre-Leukemic Cells from Primary Human De Novo Acute Myeloid Leukemia Samples into Induced Pluripotent Stem (iPS) Cells Blood. 126: 1862-1862. DOI: 10.1182/Blood.V126.23.1862.1862  0.392
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, et al. Abstract PR11: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr11  0.373
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, et al. Abstract PR03: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr03  0.372
2014 Sarkaria SM, Christopher MJ, Klco JM, Ley TJ. Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro. Leukemia. 28: 2403-6. PMID 25092143 DOI: 10.1038/Leu.2014.235  0.339
2014 Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell. 25: 379-92. PMID 24613412 DOI: 10.1016/J.Ccr.2014.01.031  0.339
2013 Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson G, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, ... Klco JM, et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia New England Journal of Medicine. 368: 2059-2074. PMID 23634996 DOI: 10.1056/Nejmoa1301689  0.35
2013 Grieselhuber NR, Klco JM, Verdoni AM, Lamprecht T, Sarkaria SM, Wartman LD, Ley TJ. Notch signaling in acute promyelocytic leukemia. Leukemia. 27: 1548-57. PMID 23455394 DOI: 10.1038/Leu.2013.68  0.327
2013 Klco JM, Spencer DH, Lamprecht TL, Sarkaria SM, Wylie T, Magrini V, Hundal J, Walker J, Varghese N, Erdmann-Gilmore P, Lichti CF, Meyer MR, Townsend RR, Wilson RK, Mardis ER, et al. Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood. 121: 1633-43. PMID 23297133 DOI: 10.1182/Blood-2012-09-459313  0.322
2013 Verdoni AM, Cole CB, Klco JM, Ley TJ. DNMT3A R882H Overexpression Leads To Hematopoietic and Skin Alterations In Transgenic Mice Blood. 122: 479-479. DOI: 10.1182/Blood.V122.21.479.479  0.305
2013 Spencer DH, Young MA, Klco JM, Ley TJ. Comprehensive Analysis Of HOX Gene Expression and DNA Methylation From 189 Primary AMLs Demonstrates Canonical Patterns Associated With Hematopoietic Stem/Progenitors and Recurrent AML Mutations Blood. 122: 2496-2496. DOI: 10.1182/Blood.V122.21.2496.2496  0.352
2013 Li C, George DR, Helton NM, Klco JM, Mudd JL, Ley TJ. Functional Early Hematopoietic Progenitor Cells Derived From Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells Blood. 122: 2421-2421. DOI: 10.1182/Blood.V122.21.2421.2421  0.317
2012 Wartman LD, Welch JS, Uy GL, Klco JM, Lamprecht T, Varghese N, Nagarajan R, Ley TJ. Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice. Plos One. 7: e46529. PMID 23056333 DOI: 10.1371/Journal.Pone.0046529  0.32
2012 Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, ... ... Klco JM, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/J.Cell.2012.06.023  0.37
2012 Mardis ER, Ding L, Westervelt P, Welch JS, Klco JM, DiPersio JF, Wilson RK, Ley TJ. Next-Generation Sequencing: A Discovery Tool for Blood Disorders Blood. 120: SCI-10-SCI-10. DOI: 10.1182/Blood.V120.21.Sci-10.Sci-10  0.366
2012 Klco JM, Spencer DH, Miller C, Lamprecht T, Fulton RS, Welch JS, Ding L, Wilson RK, Ley TJ. Deep Digital Sequencing Identifies an AML Subclone with Enhanced in Vitro and in Vivo Growth Properties Associated with Disease Relapse Blood. 120: 407-407. DOI: 10.1182/Blood.V120.21.407.407  0.372
2012 Li C, George DR, Havey NM, Klco JM, Ley TJ. Functional Hematopoietic Cells Derived From Mouse Embryonic Stem Cells. Blood. 120: 2304-2304. DOI: 10.1182/Blood.V120.21.2304.2304  0.301
2011 Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. Jama. 305: 1577-84. PMID 21505136 DOI: 10.1001/Jama.2011.497  0.312
2011 Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, et al. Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. The Journal of Clinical Investigation. 121: 1445-55. PMID 21436584 DOI: 10.1172/Jci45284  0.398
2011 Welch JS, Klco JM, Varghese N, Nagarajan R, Ley TJ. Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice. Blood. 117: 2460-8. PMID 21190992 DOI: 10.1182/Blood-2010-08-300087  0.336
2011 Grieselhuber NR, Klco JM, Verdoni AM, Ley TJ. Activation of Notch Signaling Is An Early Event in the Development of PML-Rara-Induced Acute Promyelocytic Leukemia (APL) Blood. 118: 2468-2468. DOI: 10.1182/Blood.V118.21.2468.2468  0.341
2010 Welch JS, Ding L, Chen K, Larson DE, Kulkarni S, Payton JE, Wallis J, Veizer J, McLellan MD, Vickery TL, Reed JP, Koboldt DC, Klco J, DiPersio JF, Mardis ER, et al. Resolution of a Clinical Dilemma with Whole Genome Sequencing, and Discovery of a New Mechanism for Generating PML-Rara: Insertional Fusion Blood. 116: 2755-2755. DOI: 10.1182/Blood.V116.21.2755.2755  0.343
2009 Klco JM, Sen S, Hansen JL, Lyngsø C, Nikiforovich GV, Sheikh SP, Baranski TJ. Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence. The Febs Journal. 276: 2786-800. PMID 19459935 DOI: 10.1111/J.1742-4658.2009.07002.X  0.645
2008 Hagemann IS, Miller DL, Klco JM, Nikiforovich GV, Baranski TJ. Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling. The Journal of Biological Chemistry. 283: 7763-75. PMID 18195008 DOI: 10.1074/Jbc.M709467200  0.703
2007 Sen S, Klco JM, Hansen JL, Nikiforovich GV, Sheikh SP, Baranski TJ. Dimerization/oligomerization in G protein‐coupled receptors (GPCRs) involve the participation of all transmembrane domains The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A613-A  0.626
2006 Klco JM, Nikiforovich GV, Baranski TJ. Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop. The Journal of Biological Chemistry. 281: 12010-9. PMID 16505476 DOI: 10.1074/Jbc.M600548200  0.658
2005 Klco JM, Wiegand CB, Narzinski K, Baranski TJ. Essential role for the second extracellular loop in C5a receptor activation. Nature Structural & Molecular Biology. 12: 320-6. PMID 15768031 DOI: 10.1038/Nsmb913  0.664
2003 Klco JM, Lassere TB, Baranski TJ. C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor. The Journal of Biological Chemistry. 278: 35345-53. PMID 12835319 DOI: 10.1074/Jbc.M305606200  0.657
Low-probability matches (unlikely to be authored by this person)
2020 Elsayed AH, Rafiee R, Cao X, Raimondi S, Downing JR, Ribeiro R, Fan Y, Gruber TA, Baker S, Klco J, Rubnitz JE, Pounds S, Lamba JK. Correction: A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia. Leukemia. PMID 32300185 DOI: 10.1038/S41375-020-0822-0  0.3
2017 Schwartz JR, Wang S, Ma J, Lamprecht T, Walsh M, Song G, Raimondi SC, Wu G, Walsh MF, McGee RB, Kesserwan C, Nichols KE, Cauff BE, Ribeiro RC, Wlodarski M, ... Klco JM, et al. Germline SAMD9 mutation in siblings with monosomy 7 and myelodysplastic syndrome. Leukemia. PMID 28487541 DOI: 10.1038/Leu.2017.142  0.296
2018 Rusch M, Nakitandwe J, Shurtleff S, Newman S, Zhang Z, Edmonson MN, Parker M, Jiao Y, Ma X, Liu Y, Gu J, Walsh MF, Becksfort J, Thrasher A, Li Y, ... ... Klco JM, et al. Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. Nature Communications. 9: 3962. PMID 30262806 DOI: 10.1038/S41467-018-06485-7  0.295
2011 Klco JM, Welch JS, Nguyen TT, Hurley MY, Kreisel FH, Hassan A, Lind AC, Frater JL. State of the art in myeloid sarcoma International Journal of Laboratory Hematology. 33: 555-565. PMID 21883967 DOI: 10.1111/J.1751-553X.2011.01361.X  0.294
2012 Spencer DH, Klco JM, Lamprecht T, Wylie T, Magrini V, Hundal J, Walker J, Varghese N, Meyer MR, Gilmore P, Townsend R, Mardis ER, Ley TJ. In Vitro Decitabine Treatment Demonstrates Heterogeneous Changes in Methylation and Gene Expression in Primary AML Samples. Blood. 120: 2527-2527. DOI: 10.1182/Blood.V120.21.2527.2527  0.292
2010 Welch JS, Klco J, Gao F, Hassan A, Vij R. A Phase I Dose-Escalation Study of Combination Decitabine, Arsenic Trioxide and Ascorbic Acid In Patients with MDS and AML Blood. 116: 2148-2148. DOI: 10.1182/Blood.V116.21.2148.2148  0.29
2019 Karol SE, Alexander T, Budraja A, Pounds S, Canavera KE, Wang L, Wolf J, Klco JM, Salem AH, Palenski T, Lacayo NJ, Pui C, Opferman JT, Rubnitz J. Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid Leukemia Blood. 134: 178-178. DOI: 10.1182/Blood-2019-127716  0.284
2008 Klco JM, Kreisel FH, Zehnbauer BA, Kulkarni S, Hassan A, Frater JL. The spectrum of adult B-lymphoid leukemias with BCR-ABL: molecular diagnostic, cytogenetic, and clinical laboratory perspectives. American Journal of Hematology. 83: 901-7. PMID 18932238 DOI: 10.1002/Ajh.21291  0.283
2020 Karol SE, Alexander TB, Budhraja A, Pounds SB, Canavera K, Wang L, Wolf J, Klco JM, Mead PE, Das Gupta S, Kim SY, Salem AH, Palenski T, Lacayo NJ, Pui CH, et al. Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study. The Lancet. Oncology. PMID 32171069 DOI: 10.1016/S1470-2045(20)30060-7  0.283
2010 Klco JM, Vij R, Kreisel FH, Hassan A, Frater JL. Molecular pathology of myeloproliferative neoplasms. American Journal of Clinical Pathology. 133: 602-15. PMID 20231614 DOI: 10.1309/Ajcpppz1Wfvgne4A  0.281
2004 Stickle NH, Chung J, Klco JM, Hill RP, Kaelin WG, Ohh M. pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development. Molecular and Cellular Biology. 24: 3251-61. PMID 15060148 DOI: 10.1128/Mcb.24.8.3251-3261.2004  0.28
2020 Karol SE, Cooper TM, Mead PE, Crews KR, Panetta JC, Alexander TB, Taub JW, Lacayo NJ, Heym KM, Kuo DJ, Schiff DE, Bhojwani D, Ge Y, Klco JM, Ribeiro RC, et al. Safety, pharmacokinetics, and pharmacodynamics of panobinostat in children, adolescents, and young adults with relapsed acute myeloid leukemia. Cancer. PMID 32809242 DOI: 10.1002/Cncr.33156  0.278
2018 Brown AL, Armstrong M, Lawrence D, Wang P, Arts P, Duployez N, Churpek J, Tawana K, Degelman E, Natsoulis G, Guzman ML, Patnaik MM, Shimamura A, Cantor AB, Ripperger T, ... ... Klco JM, et al. Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB Blood. 132: 5241-5241. DOI: 10.1182/Blood-2018-99-118017  0.274
2015 Griffith M, Miller CA, Griffith OL, Krysiak K, Skidmore ZL, Ramu A, Walker JR, Dang HX, Trani L, Larson DE, Demeter RT, Wendl MC, McMichael JF, Austin RE, Magrini V, ... ... Klco JM, et al. Optimizing cancer genome sequencing and analysis. Cell Systems. 1: 210-223. PMID 26645048 DOI: 10.7490/F1000Research.1110088.1  0.273
2011 Capoccia BJ, Lennerz JK, Bredemeyer AJ, Klco JM, Frater JL, Mills JC. Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells. Physiological Genomics. 43: 174-86. PMID 21098683 DOI: 10.1152/Physiolgenomics.00084.2010  0.273
2004 Olenyuk BZ, Zhang GJ, Klco JM, Nickols NG, Kaelin WG, Dervan PB. Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist. Proceedings of the National Academy of Sciences of the United States of America. 101: 16768-73. PMID 15556999 DOI: 10.1073/Pnas.0407617101  0.273
2018 Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, et al. Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. The New England Journal of Medicine. PMID 30380364 DOI: 10.1056/Nejmoa1808777  0.27
2022 Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Tian L, Liu Y, Chen X, Kolekar P, Tran Q, ... ... Klco JM, et al. Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia. Blood Cancer Discovery. PMID 35176137 DOI: 10.1158/2643-3230.BCD-21-0160  0.266
2021 Fornerod M, Ma J, Noort S, Liu Y, Walsh MP, Shi L, Nance S, Liu Y, Wang Y, Song G, Lamprecht T, Easton J, Mulder HL, Yergeau D, Myers J, ... ... Klco JM, et al. Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators. Blood Cancer Discovery. 2: 586-599. PMID 34778799 DOI: 10.1158/2643-3230.BCD-21-0049  0.266
2000 Kung AL, Wang S, Klco JM, Kaelin W.G. J, Livingston DM. Suppression of tumor growth through disruption of hypoxia-inducible transcription Nature Medicine. 6: 1335-1340. PMID 11100117 DOI: 10.1038/82146  0.265
2022 Abdelhamed S, Thomas Iii ME, Westover T, Umeda M, Xiong E, Rolle C, Walsh MP, Wu H, Schwartz JR, Valentine V, Valentine M, Pounds S, Ma J, Janke LJ, Klco JM. Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice. The Journal of Clinical Investigation. PMID 36074606 DOI: 10.1172/JCI158869  0.264
2019 Karol SE, Alexander T, Das Gupta S, Pounds SB, Canavera K, Klco JM, Lacayo NJ, Pui C, Opferman JT, Rubnitz JE. Safety and activity of venetoclax in combination with high-dose cytarabine in children with relapsed or refractory acute myeloid leukemia. Journal of Clinical Oncology. 37: 10004-10004. DOI: 10.1200/Jco.2019.37.15_Suppl.10004  0.263
2016 Schwartz J, Walsh M, Ma J, Lamprecht T, Ribeiro R, Klco J. Identifying the Genomic Landscape of Pediatric Myelodysplastic Syndromes (MDS) Clinical Lymphoma Myeloma and Leukemia. 16: S83. DOI: 10.1016/J.Clml.2016.07.117  0.261
2021 Thomas ME, Abdelhamed S, Hiltenbrand R, Schwartz JR, Sakurada SM, Walsh M, Song G, Ma J, Pruett-Miller SM, Klco JM. Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells. Leukemia. PMID 33731850 DOI: 10.1038/s41375-021-01212-6  0.258
2010 Klco JM, Geng B, Brunt EM, Hassan A, Nguyen TD, Kreisel FH, Lisker-Melman M, Frater JL. Bone marrow biopsy in patients with hepatitis C virus infection: spectrum of findings and diagnostic utility. American Journal of Hematology. 85: 106-10. PMID 20095034 DOI: 10.1002/Ajh.21600  0.257
2011 Welch JS, Klco JM, Gao F, Procknow E, Uy GL, Stockerl-Goldstein KE, Abboud CN, Westervelt P, DiPersio JF, Hassan A, Cashen AF, Vij R. Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study. American Journal of Hematology. 86: 796-800. PMID 21815182 DOI: 10.1002/Ajh.22092  0.257
2023 Klco J, Thomas M, Qi W, Walsh M, Ma J, Westover T, Abdelhamed S, Ezzell L, Rolle C, Xiong E, Rosikiewicz W, Xu B, Pruett-Miller S, Loughran A, Janke L. Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia. Research Square. PMID 37790524 DOI: 10.21203/rs.3.rs-3315059/v1  0.256
2023 Barajas JM, Umeda M, Contreras L, Khanlari M, Westover T, Walsh MP, Xiong E, Yang C, Otero B, Arribas-Layton M, Abdelhamed S, Song G, Ma X, Thomas ME, Ma J, ... Klco JM, et al. Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis. Medrxiv : the Preprint Server For Health Sciences. PMID 38014207 DOI: 10.1101/2023.11.13.23298320  0.256
2024 Thomas ME, Qi W, Walsh MP, Ma J, Westover T, Abdelhamed S, Ezzell LJ, Rolle C, Xiong E, Rosikiewicz W, Xu B, Loughran AJ, Pruett-Miller SM, Janke LJ, Klco JM. Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia. Leukemia. PMID 38454121 DOI: 10.1038/s41375-024-02193-y  0.255
2024 Barajas JM, Umeda M, Contreras L, Khanlari M, Westover T, Walsh MP, Xiong E, Yang C, Otero B, Arribas-Layton M, Abdelhamed S, Song G, Ma X, Thomas Rd ME, Ma J, ... Klco JM, et al. tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis. Haematologica. PMID 38426285 DOI: 10.3324/haematol.2023.284683  0.254
2023 Kirkham JK, Liu YC, Foy SG, Ma J, Gheorghe G, Furtado LV, Popescu MI, Klco JM, Karol SE, Blackburn PR. Clinical and genomic characterization of an ATRA-insensitive acute promyelocytic leukemia variant with a FNDC3B::RARB fusion. Genes, Chromosomes & Cancer. PMID 37283355 DOI: 10.1002/gcc.23180  0.25
2023 Barajas JM, Rasouli M, Umeda M, Hiltenbrand RL, Abdelhamed S, Mohnani R, Arthur B, Westover T, Thomas ME, Ashtiani M, Janke LJ, Xu B, Chang TC, Rosikiewicz W, Xiong E, ... ... Klco JM, et al. Acute myeloid leukemias with UBTF tandem duplications are sensitive to Menin inhibitors. Blood. PMID 37890156 DOI: 10.1182/blood.2023021359  0.248
2011 Klco JM, Kulkarni S, Kreisel FH, Nguyen TD, Hassan A, Frater JL. Immunohistochemical analysis of monocytic leukemias: usefulness of CD14 and Kruppel-like factor 4, a novel monocyte marker. American Journal of Clinical Pathology. 135: 720-30. PMID 21502426 DOI: 10.1309/Ajcpz46Pmmawjrot  0.233
2011 Amador-Ortiz C, Hurley MY, Ghahramani GK, Frisch S, Klco JM, Lind AC, Nguyen TT, Hassan A, Kreisel FH, Frater JL. Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma. Journal of Cutaneous Pathology. 38: 945-53. PMID 22050091 DOI: 10.1111/J.1600-0560.2011.01809.X  0.23
2017 Zhang J, Griffith M, Miller CA, Griffith OL, Spencer DH, Walker JR, Magrini V, McGrath SD, Ly A, Helton NM, Trissal M, Link DC, Dang HX, Larson DE, Kulkarni S, ... ... Klco JM, et al. Comprehensive discovery of non-coding RNAs in acute myeloid leukemia cell transcriptomes. Experimental Hematology. PMID 28760689 DOI: 10.1016/J.Exphem.2017.07.008  0.228
2018 Schwartz JR, Walsh MP, Ma J, Lamprecht T, Wang S, Wu G, Raimondi S, Triplett B, Klco J. Clonal Dynamics of Donor-Derived MDS after Unrelated-HCT for High-Risk Pediatric B-Lymphoblastic Leukemia. Cold Spring Harbor Molecular Case Studies. PMID 29891567 DOI: 10.1101/mcs.a002980  0.219
2021 Montefiori LE, Bendig S, Gu Z, Chen X, Polonen P, Ma X, Murison A, Zeng A, Garcia-Prat L, Dickerson K, Iacobucci I, Abdelhamed S, Hiltenbrand R, Mead PE, Mehr CM, ... ... Klco JM, et al. Enhancer hijacking drives oncogenic BCL11B expression in lineage ambiguous stem cell leukemia. Cancer Discovery. PMID 34103329 DOI: 10.1158/2159-8290.CD-21-0145  0.219
2020 Klco JM, Mullighan CG. Advances in germline predisposition to acute leukaemias and myeloid neoplasms. Nature Reviews. Cancer. PMID 33328584 DOI: 10.1038/s41568-020-00315-z  0.218
2024 Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Yang W, Fan Y, ... ... Klco JM, et al. A new genomic framework to categorize pediatric acute myeloid leukemia. Nature Genetics. PMID 38212634 DOI: 10.1038/s41588-023-01640-3  0.217
2023 Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek J, Rusch M, Rahbarinia D, Foy S, Huang B, Walsh M, Kumar P, Liu Y, Fan Y, Wu G, ... ... Klco J, et al. Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis. Research Square. PMID 37398194 DOI: 10.21203/rs.3.rs-2925426/v1  0.217
2024 Ma J, Liu YC, Voss RK, Ma J, Palagani A, Caldwell E, Rosikiewicz W, Cardenas M, Foy S, Umeda M, Wilkinson MR, Inaba H, Klco JM, Rubnitz JE, Wang L. Genomic and global gene expression profiling in pediatric and young adult acute leukemia with PICALM::MLLT10 Fusion. Leukemia. PMID 38429501 DOI: 10.1038/s41375-024-02194-x  0.214
2022 Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, ... ... Klco JM, et al. Genomic Profiling for Clinical Decision Making in Myeloid Neoplasms and Acute Leukemia. Blood. PMID 36130297 DOI: 10.1182/blood.2022015853  0.211
2021 Yang F, Brady SW, Tang C, Sun H, Du L, Barz MJ, Ma X, Chen Y, Fang H, Li X, Kolekar P, Pathak O, Cai J, Ding L, Wang T, ... ... Klco JM, et al. Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse. Nature Cancer. 2: 819-834. PMID 35122027 DOI: 10.1038/s43018-021-00230-8  0.205
2021 Schwartz JR, Ma J, Kamens J, Westover T, Walsh MP, Brady SW, Robert Michael J, Chen X, Montefiori L, Song G, Wu G, Wu H, Branstetter C, Hiltenbrand R, Walsh MF, ... ... Klco JM, et al. The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms. Nature Communications. 12: 985. PMID 33579957 DOI: 10.1038/s41467-021-21255-8  0.198
2024 Wong JC, Weinfurtner KM, Westover T, Kim J, Lebish EJ, Del Pilar Alzamora M, Huang BJ, Walsh M, Abdelhamed S, Ma J, Klco JM, Shannon K. 5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies. Leukemia. PMID 38443608 DOI: 10.1038/s41375-024-02205-x  0.181
2023 Khanlari M, Wang L, Bolen CY, Otanez FSB, Furtado LV, Key L, Irwin L, Wang W, Klco JM. -positive acute leukemia with RAM and mixed T/megakaryocytic phenotype. Ejhaem. 4: 765-769. PMID 37601875 DOI: 10.1002/jha2.741  0.18
2022 Ryland G, Umeda M, Holmfeldt L, Lehmann S, Herlin MK, Ma JJ, Khanlari M, Rubnitz JE, Ries RE, Kosasih HJ, Ekert PG, Goh HN, Tiong IS, Grimmond SM, Haferlach C, ... ... Klco JM, et al. Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions. Blood. PMID 36179268 DOI: 10.1182/blood.2022017874  0.176
2023 Liu Y, Klein J, Bajpai R, Dong L, Tran Q, Kolekar P, Smith JL, Ries RE, Huang BJ, Wang YC, Alonzo TA, Tian L, Mulder HL, Shaw TI, Ma J, ... ... Klco JM, et al. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication. Nature Communications. 14: 1739. PMID 37019972 DOI: 10.1038/s41467-023-37438-4  0.17
2021 Newman S, Nakitandwe J, Kesserwan CA, Azzato EM, Wheeler DA, Rusch M, Shurtleff S, Hedges DJ, Hamilton KV, Foy SG, Edmonson MN, Thrasher A, Bahrami A, Orr BA, Klco JM, et al. Genomes for Kids: The scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing. Cancer Discovery. PMID 34301788 DOI: 10.1158/2159-8290.CD-20-1631  0.169
2024 Zoine JT, Immadisetty K, Ibanez-Vega J, Moore SE, Nevitt C, Thanekar U, Tian L, Karouni A, Chockley PJ, Arthur B, Sheppard H, Klco JM, Langfitt DM, Krenciute G, Gottschalk S, et al. Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity. Cell Reports. Medicine. 101422. PMID 38350450 DOI: 10.1016/j.xcrm.2024.101422  0.161
2022 Hebbar N, Epperly R, Vaidya A, Thanekar U, Moore SE, Umeda M, Ma J, Patil SL, Langfitt D, Huang S, Cheng C, Klco JM, Gottschalk S, Velasquez MP. CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells. Nature Communications. 13: 587. PMID 35102167 DOI: 10.1038/s41467-022-28243-6  0.16
2001 Hoffman MA, Ohh M, Yang H, Klco JM, Ivan M, Kaelin WG. von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF. Human Molecular Genetics. 10: 1019-27. PMID 11331612 DOI: 10.1093/Hmg/10.10.1019  0.16
2022 Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, ... ... Klco JM, et al. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nature Communications. 13: 5487. PMID 36123353 DOI: 10.1038/s41467-022-33244-6  0.159
2021 Chandra B, Michmerhuizen NL, Shirnekhi HK, Tripathi S, Pioso BJ, Baggett DW, Mitrea DM, Iacobucci I, White MR, Chen J, Park CG, Wu H, Pounds S, Medyukhina A, Khairy K, ... ... Klco JM, et al. Phase Separation mediates NUP98 Fusion Oncoprotein Leukemic Transformation. Cancer Discovery. PMID 34903620 DOI: 10.1158/2159-8290.CD-21-0674  0.157
2023 Marrero RJ, Cao X, Wu H, Elsayed AH, Klco JM, Ribeiro RC, Rubnitz JE, Ma X, Meshinchi S, Aplenc R, Kolb EA, Ries RE, Alonzo T, Pounds SB, Lamba JK. SAMHD1 Single Nucleotide Polymorphisms Impact Outcome in Children with Newly Diagnosed Acute Myeloid Leukemia. Blood Advances. PMID 36689724 DOI: 10.1182/bloodadvances.2022009088  0.152
2023 Homan CC, Drazer MW, Yu K, Lawrence DM, Feng J, Arriola-Martinez LA, Pozsgai MJ, McNeely KE, Ha TT, Venugopal P, Arts P, King-Smith S, Cheah JJ, Armstrong M, Wang P, ... ... Klco JM, et al. Somatic mutational landscape of hereditary hematopoietic malignancies caused by germ line RUNX1, GATA2, and DDX41 variants. Blood Advances. PMID 37406166 DOI: 10.1182/bloodadvances.2023010045  0.151
2021 Caldwell KJ, Budhraja A, Opferman JT, Pui CH, Klco JM, Rubnitz JE. Activity of venetoclax against relapsed acute undifferentiated leukemia. Cancer. PMID 33823069 DOI: 10.1002/cncr.33531  0.147
2021 Liu APY, Smith KS, Kumar R, Paul L, Bihannic L, Lin T, Maass KK, Pajtler KW, Chintagumpala M, Su JM, Bouffet E, Fisher MJ, Gururangan S, Cohn R, Hassall T, ... ... Klco JM, et al. Serial assessment of measurable residual disease in medulloblastoma liquid biopsies. Cancer Cell. PMID 34678152 DOI: 10.1016/j.ccell.2021.09.012  0.146
2021 Abdelhamed S, Butler JT, Jung S, Chen DW, Jenkins GN, Gao L, Lim J, Klco JM, Horton TM, Kurre P. Rational biomarker development for the early and minimally invasive monitoring of AML. Blood Advances. PMID 34587228 DOI: 10.1182/bloodadvances.2021004621  0.145
2003 Jiang Y, Zhang W, Kondo K, Klco JM, St Martin TB, Dufault MR, Madden SL, Kaelin WG, Nacht M. Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways. Molecular Cancer Research : McR. 1: 453-62. PMID 12692265  0.136
2023 Karol SE, Coustan-Smith E, Pounds SB, Wang L, Inaba H, Ribeiro RC, Pui CH, Klco JM, Rubnitz JE. Clinical Impact of Minimal Residual Disease in Blood and Bone Marrow of Children with Acute Myeloid Leukemia. Blood Advances. PMID 37058475 DOI: 10.1182/bloodadvances.2022009534  0.136
2019 Rubnitz JE, Lacayo NJ, Inaba H, Heym K, Ribeiro RC, Taub J, McNeer J, Degar B, Schiff D, Yeoh AE, Coustan-Smith E, Wang L, Triplett B, Raimondi SC, Klco J, et al. Clofarabine Can Replace Anthracyclines and Etoposide in Remission Induction Therapy for Childhood Acute Myeloid Leukemia: The AML08 Multicenter, Randomized Phase III Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1900327. PMID 31246522 DOI: 10.1200/Jco.19.00327  0.134
2024 Nishiguchi G, Mascibroda LG, Young SM, Caine EA, Abdelhamed S, Kooijman JJ, Miller DJ, Das S, McGowan K, Mayasundari A, Shi Z, Barajas JM, Hiltenbrand R, Aggarwal A, Chang Y, ... ... Klco JM, et al. Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines. Nature Communications. 15: 482. PMID 38228616 DOI: 10.1038/s41467-024-44698-1  0.133
2023 Kolekar P, Balagopal V, Dong L, Liu Y, Foy S, Tran Q, Mulder H, Huskey AL, Plyler E, Liang Z, Ma J, Nakitandwe J, Gu J, Maciaszek J, Payne-Turner D, ... ... Klco JM, et al. SJPedPanel: A pan-cancer gene panel for childhood malignancies. Medrxiv : the Preprint Server For Health Sciences. PMID 38076942 DOI: 10.1101/2023.11.27.23299068  0.118
2022 Freiwan A, Zoine J, Crawford JC, Vaidya A, Schattgen SA, Myers J, Patil SL, Khanlari M, Inaba H, Klco JM, Mullighan CG, Krenciute G, Chockley P, Naik S, Langfitt D, et al. Engineering Naturally Occurring CD7 Negative T Cells for the Immunotherapy of Hematological Malignancies. Blood. PMID 35914226 DOI: 10.1182/blood.2021015020  0.117
2023 Khanlari M, Wang W, Liu YC, Wang L, Rubnitz JE, Dixon S, Orr BA, Anelo OM, Cheng Z, Balagopal V, Klco JM. Concurrent peripheral T-cell lymphoma and T-cell lymphoblastic leukemia/lymphoma with identical :: fusion events. Haematologica. PMID 37767572 DOI: 10.3324/haematol.2023.283585  0.112
2023 Koravovic M, Mayasundari A, Tasic G, Keramatnia F, Stachowski TR, Cui H, Chai SC, Jonchere B, Yang L, Li Y, Fu X, Hiltenbrand R, Paul L, Mishra V, Klco JM, et al. From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors. European Journal of Medicinal Chemistry. 251: 115246. PMID 36898329 DOI: 10.1016/j.ejmech.2023.115246  0.108
2015 Griffith M, Miller CA, Griffith OL, Krysiak K, Skidmore ZL, Ramu A, Walker JR, Dang HX, Trani L, Larson DE, Demeter RT, Wendl MC, McMichael JF, Austin RE, Magrini V, ... ... Klco JM, et al. Optimizing Cancer Genome Sequencing and Analysis Cell Systems. 1: 210-223. DOI: 10.1016/j.cels.2015.08.015  0.089
2021 Homan CC, King-Smith SL, Lawrence DM, Arts P, Feng J, Andrews J, Armstrong M, Ha T, Dobbins J, Drazer MW, Yu K, Bödör C, Cantor A, Cazzola M, Degelman E, ... ... Klco JM, et al. The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy. Haematologica. PMID 34233450 DOI: 10.3324/haematol.2021.278762  0.088
2021 Davis EM, Sun Y, Liu Y, Kolekar P, Shao Y, Szlachta K, Mulder HL, Ren D, Rice SV, Wang Z, Nakitandwe J, Gout AM, Shaner B, Hall S, Robison LL, ... ... Klco JM, et al. SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data. Genome Biology. 22: 37. PMID 33487172 DOI: 10.1186/s13059-020-02254-2  0.085
2017 Francis OL, Chaudhry KK, Lamprecht T, Klco JM. Impact of Notch disruption on myeloid development. Blood Cancer Journal. 7: e598. PMID 28841212 DOI: 10.1038/bcj.2017.73  0.081
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