| Year |
Citation |
Score |
| 2012 |
Zhao M, Sachs PC, Wang X, Dumur CI, Idowu MO, Robila V, Francis MP, Ware J, Beckman M, Rizki A, Holt SE, Elmore LW. Mesenchymal stem cells in mammary adipose tissue stimulate progression of breast cancer resembling the basal-type. Cancer Biology & Therapy. 13: 782-92. PMID 22669576 DOI: 10.4161/Cbt.20561 |
0.751 |
|
| 2012 |
Sachs PC, Francis MP, Zhao M, Brumelle J, Rao RR, Elmore LW, Holt SE. Defining essential stem cell characteristics in adipose-derived stromal cells extracted from distinct anatomical sites. Cell and Tissue Research. 349: 505-15. PMID 22628159 DOI: 10.1007/S00441-012-1423-7 |
0.737 |
|
| 2012 |
Francis MP, Sachs PC, Madurantakam PA, Sell SA, Elmore LW, Bowlin GL, Holt SE. Electrospinning adipose tissue-derived extracellular matrix for adipose stem cell culture. Journal of Biomedical Materials Research. Part A. 100: 1716-24. PMID 22447769 DOI: 10.1002/Jbm.A.34126 |
0.703 |
|
| 2012 |
Holt S, Gollahon L, Willingham T, Barbosa M, Shay J. p53 levels in human mammary epithelial cells expressing wild-type and mutant human papillomavirus type 16 (HPV-16) E6 proteins. International Journal of Oncology. 8: 263-70. PMID 21544354 DOI: 10.3892/Ijo.8.2.263 |
0.448 |
|
| 2011 |
Chen MY, Clark AJ, Chan DC, Ware JL, Holt SE, Chidambaram A, Fillmore HL, Broaddus WC. Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression. Journal of Neuro-Oncology. 103: 87-102. PMID 20820871 DOI: 10.1007/S11060-010-0374-7 |
0.366 |
|
| 2011 |
Diehl MC, Idowu MO, Kimmelshue KN, York TP, Jackson-Cook CK, Turner KC, Holt SE, Elmore LW. Elevated TRF2 in advanced breast cancers with short telomeres. Breast Cancer Research and Treatment. 127: 623-30. PMID 20625812 DOI: 10.1007/S10549-010-0988-7 |
0.771 |
|
| 2011 |
Kmieciak M, Worschech A, Nikizad H, Gowda M, Habibi M, Depcrynski A, Wang E, Godder K, Holt SE, Marincola FM, Manjili MH. CD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancer. Breast Cancer Research and Treatment. 126: 385-94. PMID 20480224 DOI: 10.1007/S10549-010-0942-8 |
0.359 |
|
| 2010 |
Zhao M, Dumur CI, Holt SE, Beckman MJ, Elmore LW. Multipotent adipose stromal cells and breast cancer development: Think globally, act locally. Molecular Carcinogenesis. 49: 923-7. PMID 20842668 DOI: 10.1002/Mc.20675 |
0.446 |
|
| 2010 |
Francis MP, Sachs PC, Elmore LW, Holt SE. Isolating adipose-derived mesenchymal stem cells from lipoaspirate blood and saline fraction. Organogenesis. 6: 11-4. PMID 20592860 DOI: 10.4161/Org.6.1.10019 |
0.714 |
|
| 2009 |
Nguyen BN, Elmore LW, Holt SE. Mechanism of dominant-negative telomerase function. Cell Cycle (Georgetown, Tex.). 8: 3227-33. PMID 19738429 DOI: 10.4161/Cc.8.19.9788 |
0.395 |
|
| 2009 |
Diehl MC, Idowu MO, Kimmelshue K, York TP, Elmore LW, Holt SE. Elevated expression of nuclear Hsp90 in invasive breast tumors. Cancer Biology & Therapy. 8: 1952-61. PMID 19738418 DOI: 10.4161/Cbt.8.20.9639 |
0.759 |
|
| 2009 |
Poynter KR, Sachs PC, Bright AT, Breed MS, Nguyen BN, Elmore LW, Holt SE. Genetic inhibition of telomerase results in sensitization and recovery of breast tumor cells. Molecular Cancer Therapeutics. 8: 1319-27. PMID 19417141 DOI: 10.1158/1535-7163.Mct-08-0849 |
0.768 |
|
| 2009 |
Au DW, Mok HO, Elmore LW, Holt SE. Japanese medaka: a new vertebrate model for studying telomere and telomerase biology. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 149: 161-7. PMID 18790082 DOI: 10.1016/J.Cbpc.2008.08.005 |
0.399 |
|
| 2008 |
Elmore LW, Forsythe R, Forsythe H, Bright AT, Nasim S, Endo K, Holt SE. Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas. Oncology Reports. 20: 613-7. PMID 18695913 DOI: 10.3892/Or_00000049 |
0.327 |
|
| 2008 |
Gewirtz DA, Holt SE, Elmore LW. Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. Biochemical Pharmacology. 76: 947-57. PMID 18657518 DOI: 10.1016/J.Bcp.2008.06.024 |
0.381 |
|
| 2008 |
Strub GM, Depcrynski A, Elmore LW, Holt SE. Recovery from stress is a function of age and telomere length. Cell Stress & Chaperones. 13: 475-82. PMID 18491040 DOI: 10.1007/S12192-008-0047-Z |
0.398 |
|
| 2008 |
Elmore LW, Norris MW, Sircar S, Bright AT, McChesney PA, Winn RN, Holt SE. Upregulation of telomerase function during tissue regeneration. Experimental Biology and Medicine (Maywood, N.J.). 233: 958-67. PMID 18480423 DOI: 10.3181/0712-Rm-345 |
0.424 |
|
| 2008 |
Xing JG, Lee LE, Fan L, Collodi P, Holt SE, Bols NC. Initiation of a zebrafish blastula cell line on rainbow trout stromal cells and subsequent development under feeder-free conditions into a cell line, ZEB2J. Zebrafish. 5: 49-63. PMID 18399791 DOI: 10.1089/Zeb.2007.0512 |
0.417 |
|
| 2008 |
Di X, Bright AT, Bellott R, Gaskins E, Robert J, Holt S, Gewirtz D, Elmore L. A chemotherapy-associated senescence bystander effect in breast cancer cells. Cancer Biology & Therapy. 7: 864-72. PMID 18340112 DOI: 10.4161/Cbt.7.6.5861 |
0.491 |
|
| 2008 |
Di X, Bright AT, Bellott R, Gaskins E, Robert J, Holt S, Gewirtz D, Elmore L. A chemotherapy-associated senescence bystander effect in breast cancer cells Cancer Biology and Therapy. 7: 682-690. |
0.317 |
|
| 2007 |
Richardson RM, Nguyen B, Holt SE, Broaddus WC, Fillmore HL. Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells. Neuroscience Letters. 421: 168-72. PMID 17566647 DOI: 10.1016/J.Neulet.2007.03.079 |
0.409 |
|
| 2007 |
Elmore LW, Holt SE. Telomerase inhibition as an adjuvant anticancer therapy: it is more than just a waiting game. Expert Opinion On Therapeutic Targets. 11: 427-30. PMID 17373872 DOI: 10.1517/14728222.11.4.427 |
0.447 |
|
| 2006 |
Compton SA, Elmore LW, Haydu K, Jackson-Cook CK, Holt SE. Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells. Molecular and Cellular Biology. 26: 1452-62. PMID 16449656 DOI: 10.1128/Mcb.26.4.1452-1462.2006 |
0.732 |
|
| 2006 |
Poynter KR, Elmore LW, Holt SE. Telomeres and telomerase in aging and cancer: Lessons learned from experimental model systems Drug Discovery Today: Disease Models. 3: 155-160. DOI: 10.1016/J.Ddmod.2006.05.004 |
0.388 |
|
| 2005 |
McChesney PA, Elmore LW, Holt SE. Vertebrate marine species as model systems for studying telomeres and telomerase. Zebrafish. 1: 349-55. PMID 18248213 DOI: 10.1089/Zeb.2005.1.349 |
0.422 |
|
| 2005 |
Lai GH, Zhang Z, Shen XN, Ward DJ, Dewitt JL, Holt SE, Rozich RA, Hixson DC, Sirica AE. erbB-2/neu transformed rat cholangiocytes recapitulate key cellular and molecular features of human bile duct cancer. Gastroenterology. 129: 2047-57. PMID 16344070 DOI: 10.1053/J.Gastro.2005.10.010 |
0.346 |
|
| 2005 |
Jones KR, Elmore LW, Jackson-Cook C, Demasters G, Povirk LF, Holt SE, Gewirtz DA. p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells. International Journal of Radiation Biology. 81: 445-58. PMID 16308915 DOI: 10.1080/09553000500168549 |
0.498 |
|
| 2005 |
Elmore LW, Di X, Dumur C, Holt SE, Gewirtz DA. Evasion of a single-step, chemotherapy-induced senescence in breast cancer cells: implications for treatment response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2637-43. PMID 15814644 DOI: 10.1158/1078-0432.Ccr-04-1462 |
0.409 |
|
| 2004 |
Leach NT, Rehder C, Jensen K, Holt S, Jackson-Cook C. Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy Mechanisms of Ageing and Development. 125: 563-573. PMID 15336914 DOI: 10.1016/J.Mad.2004.06.006 |
0.617 |
|
| 2004 |
McChesney PA, Turner KC, Jackson-Cook C, Elmore LW, Holt SE. Telomerase resets the homeostatic telomere length and prevents telomere dysfunction in immortalized human cells. Dna and Cell Biology. 23: 293-300. PMID 15199944 DOI: 10.1089/104454904323090921 |
0.502 |
|
| 2004 |
Wise SS, Elmore LW, Holt SE, Little JE, Antonucci PG, Bryant BH, Wise JP. Telomerase-mediated lifespan extension of human bronchial cells does not affect hexavalent chromium-induced cytotoxicity or genotoxicity. Molecular and Cellular Biochemistry. 255: 103-11. PMID 14971651 DOI: 10.1023/B:Mcbi.0000007266.82705.D9 |
0.402 |
|
| 2003 |
Nguyen B, Elmore LW, Holt SE. Telomerase as a target for cancer immunotherapy. Cancer Biology & Therapy. 2: 131-6. PMID 12750550 DOI: 10.4161/Cbt.2.2.255 |
0.488 |
|
| 2002 |
McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells. Cancer Biology & Therapy. 1: 243-53. PMID 12432271 DOI: 10.4161/Cbt.75 |
0.363 |
|
| 2002 |
Elmore LW, Turner KC, Gollahon LS, Landon MR, Jackson-Cook CK, Holt SE. Telomerase protects cancer-prone human cells from chromosomal instability and spontaneous immortalization. Cancer Biology & Therapy. 1: 391-7. PMID 12432253 DOI: 10.4161/Cbt.1.4.13 |
0.497 |
|
| 2002 |
Elmore LW, Forsythe HL, Ferreira-Gonzalez A, Garrett CT, Clark GM, Holt SE. Real-time quantitative analysis of telomerase activity in breast tumor specimens using a highly specific and sensitive fluorescent-based assay. Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 11: 177-85. PMID 12218458 DOI: 10.1097/00019606-200209000-00009 |
0.408 |
|
| 2002 |
Elmore LW, Rehder CW, Di X, McChesney PA, Jackson-Cook CK, Gewirtz DA, Holt SE. Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction. The Journal of Biological Chemistry. 277: 35509-15. PMID 12101184 DOI: 10.1074/Jbc.M205477200 |
0.501 |
|
| 2002 |
Forsythe HL, Elmore LW, Jensen KO, Landon MR, Holt SE. Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage. International Journal of Oncology. 20: 1137-43. PMID 12011990 DOI: 10.3892/Ijo.20.6.1137 |
0.458 |
|
| 2002 |
Holt SE, Brown EJ, Zipursky A. Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome. Journal of Pediatric Hematology/Oncology. 24: 14-7. PMID 11902731 DOI: 10.1097/00043426-200201000-00005 |
0.326 |
|
| 2001 |
Morales CP, Holt SE. Detection of telomerase by in situ hybridization and by the polymerase chain reaction-based telomerase activity assay. Methods in Molecular Medicine. 49: 43-58. PMID 21370132 DOI: 10.1385/1-59259-081-0:43 |
0.422 |
|
| 2001 |
Akalin A, Elmore LW, Forsythe HL, Amaker BA, McCollum ED, Nelson PS, Ware JL, Holt SE. A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression. Cancer Research. 61: 4791-6. PMID 11406554 |
0.573 |
|
| 2001 |
Forsythe HL, Jarvis JL, Turner JW, Elmore LW, Holt SE. Stable association of hsp90 and p23, but Not hsp70, with active human telomerase. The Journal of Biological Chemistry. 276: 15571-4. PMID 11274138 DOI: 10.1074/Jbc.C100055200 |
0.333 |
|
| 2001 |
Elmore LW, Holt SE. Cell. proliferation, telomerase, and cancer Advances in Cell Aging and Gerontology. 8: 89-102. DOI: 10.1016/S1566-3124(01)08005-1 |
0.539 |
|
| 2000 |
Gollahon LS, Holt SE. Alternative methods of extracting telomerase activity from human tumor samples. Cancer Letters. 159: 141-9. PMID 10996725 DOI: 10.1016/S0304-3835(00)00544-9 |
0.327 |
|
| 2000 |
Elmore LW, Holt SE. Telomerase and telomere stability: a new class of tumor suppressor? Molecular Carcinogenesis. 28: 1-4. PMID 10820482 DOI: 10.1002/(Sici)1098-2744(200005)28:1<1::Aid-Mc1>3.0.Co;2-N |
0.432 |
|
| 2000 |
Ouellette MM, Liao M, Herbert BS, Johnson M, Holt SE, Liss HS, Shay JW, Wright WE. Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. The Journal of Biological Chemistry. 275: 10072-6. PMID 10744686 DOI: 10.1074/Jbc.275.14.10072 |
0.581 |
|
| 2000 |
Savre-Train I, Gollahon LS, Holt SE. Clonal heterogeneity in telomerase activity and telomere length in tumor-derived cell lines. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 223: 379-88. PMID 10721008 |
0.412 |
|
| 2000 |
Elmore L, Akalin A, Gollahon L, Clarke G, Grimes M, Burks R, Ferreira-Gonzalez A, Garrett C, Holt S. Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues Breast Cancer Research. 2: 1-1. DOI: 10.1186/Bcr120 |
0.439 |
|
| 1999 |
Tesmer VM, Ford LP, Holt SE, Frank BC, Yi X, Aisner DL, Ouellette M, Shay JW, Wright WE. Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro. Molecular and Cellular Biology. 19: 6207-16. PMID 10454567 DOI: 10.1128/Mcb.19.9.6207 |
0.511 |
|
| 1999 |
Holt SE, Glinsky VV, Ivanova AB, Glinsky GV. Resistance to apoptosis in human cells conferred by telomerase function and telomere stability. Molecular Carcinogenesis. 25: 241-8. PMID 10449030 DOI: 10.1002/(Sici)1098-2744(199908)25:4<241::Aid-Mc2>3.0.Co;2-9 |
0.411 |
|
| 1999 |
Holt SE, Shay JW. Role of telomerase in cellular proliferation and cancer. Journal of Cellular Physiology. 180: 10-8. PMID 10362013 DOI: 10.1002/(Sici)1097-4652(199907)180:1<10::Aid-Jcp2>3.0.Co;2-D |
0.651 |
|
| 1999 |
Holt SE, Aisner DL, Baur J, Tesmer VM, Dy M, Ouellette M, Trager JB, Morin GB, Toft DO, Shay JW, Wright WE, White MA. Functional requirement of p23 and Hsp90 in telomerase complexes. Genes & Development. 13: 817-26. PMID 10197982 DOI: 10.1101/Gad.13.7.817 |
0.554 |
|
| 1999 |
Morales CP, Holt SE, Ouellette M, Kaur KJ, Yan Y, Wilson KS, White MA, Wright WE, Shay JW. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nature Genetics. 21: 115-8. PMID 9916803 DOI: 10.1038/5063 |
0.583 |
|
| 1998 |
Norton JC, Holt SE, Wright WE, Shay JW. Enhanced detection of human telomerase activity. Dna and Cell Biology. 17: 217-9. PMID 9539101 DOI: 10.1089/Dna.1998.17.217 |
0.527 |
|
| 1998 |
Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE. Extension of life-span by introduction of telomerase into normal human cells. Science (New York, N.Y.). 279: 349-52. PMID 9454332 DOI: 10.1126/Science.279.5349.349 |
0.596 |
|
| 1997 |
Weinrich SL, Pruzan R, Ma L, Ouellette M, Tesmer VM, Holt SE, Bodnar AG, Lichtsteiner S, Kim NW, Trager JB, Taylor RD, Carlos R, Andrews WH, Wright WE, Shay JW, et al. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nature Genetics. 17: 498-502. PMID 9398860 DOI: 10.1038/Ng1297-498 |
0.604 |
|
| 1997 |
Holt SE, Aisner DL, Shay JW, Wright WE. Lack of cell cycle regulation of telomerase activity in human cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 10687-92. PMID 9380696 DOI: 10.1073/Pnas.94.20.10687 |
0.58 |
|
| 1997 |
Holt SE, Wright WE, Shay JW. Multiple pathways for the regulation of telomerase activity. European Journal of Cancer (Oxford, England : 1990). 33: 761-6. PMID 9282114 DOI: 10.1016/S0959-8049(97)00066-X |
0.648 |
|
| 1996 |
Holt SE, Shay JW, Wright WE. Refining the telomere-telomerase hypothesis of aging and cancer. Nature Biotechnology. 14: 836-9. PMID 9631006 DOI: 10.1038/Nbt0796-836 |
0.523 |
|
| 1996 |
Holt SE, Wright WE, Shay JW. Regulation of telomerase activity in immortal cell lines. Molecular and Cellular Biology. 16: 2932-9. PMID 8649404 DOI: 10.1128/Mcb.16.6.2932 |
0.628 |
|
| 1996 |
Holt SE, Norton JC, Wright WE, Shay JW. Comparison of the telomeric repeat amplification protocol (TRAP) to the new TRAP-eze telomerase detection kit Methods in Cell Science. 18: 237-248. DOI: 10.1007/BF00132889 |
0.389 |
|
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