Kathryn Haskins - Publications

Affiliations: 
Molecular Biology University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology, Molecular Biology, Cell Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Callebaut A, Guyer P, Baker RL, Gallegos JB, Hohenstein AC, Gottlieb PA, Mathieu C, Overbergh L, Haskins K, James EA. An Insulin-Chromogranin A Hybrid Peptide activates DR11 restricted T cells in human type 1 diabetes. Diabetes. PMID 38295386 DOI: 10.2337/db23-0622  0.449
2023 Wenzlau JM, Gu Y, Michels A, Rewers M, Haskins K, Yu L. Identification of Autoantibodies to a Hybrid Insulin Peptide in Type 1 Diabetes. Diagnostics (Basel, Switzerland). 13. PMID 37685398 DOI: 10.3390/diagnostics13172859  0.314
2022 Crawford SA, Wiles TA, Wenzlau JM, Powell RL, Barbour G, Dang M, Groegler J, Barra JM, Burnette KS, Hohenstein AC, Baker RL, Tse HM, Haskins K, Delong T. Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes. Diabetes. PMID 36041196 DOI: 10.2337/db22-0303  0.451
2022 Wenzlau JM, DiLisio JE, Barbour G, Dang M, Hohenstein AC, Nakayama M, Delong T, Baker RL, Haskins K. Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes. Frontiers in Immunology. 13: 926650. PMID 36032090 DOI: 10.3389/fimmu.2022.926650  0.436
2022 Jamison BL, DiLisio JE, Beard KS, Neef T, Bradley B, Goodman J, Gill RG, Miller SD, Baker RL, Haskins K. Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the Non-Obese Diabetic (NOD) Mouse. Diabetes. PMID 35007324 DOI: 10.2337/db20-1170  0.491
2021 Neef T, Ifergan I, Beddow S, Penaloza-MacMaster P, Haskins K, Shea LD, Podojil JR, Miller SD. Tolerance Induced by Antigen-Loaded PLG Nanoparticles Affects the Phenotype and Trafficking of Transgenic CD4 and CD8 T Cells. Cells. 10. PMID 34943952 DOI: 10.3390/cells10123445  0.458
2021 Wiles TA, Hohenstein A, Landry LG, Dang M, Powell R, Guyer P, James EA, Nakayama M, Haskins K, Delong T, Baker RL. Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide. Frontiers in Immunology. 12: 668680. PMID 34113344 DOI: 10.3389/fimmu.2021.668680  0.486
2021 DiLisio JE, Haskins K. Induction of Antigen-Specific Tolerance in Autoimmune Diabetes with Nanoparticles Containing Hybrid Insulin Peptides. Biomedicines. 9. PMID 33673706 DOI: 10.3390/biomedicines9030240  0.493
2020 Haskins K, Wenzlau J. Cluster of Differentiation 4 T Cells and Neoantigens in Autoimmune Diabetes. Critical Reviews in Immunology. 40: 441-446. PMID 33463955 DOI: 10.1615/CritRevImmunol.2020034833  0.508
2020 Dai YD, Dias P, Margosiak A, Marquardt K, Bashratyan R, Hu WY, Haskins K, Evans LH. Endogenous retrovirus gag antigen and its gene variants are unique autoantigens expressed in the pancreatic islets of non-obese diabetic mice. Immunology Letters. PMID 32335144 DOI: 10.1016/J.Imlet.2020.04.007  0.534
2020 Arribas-Layton D, Guyer P, Delong T, Dang M, Chow IT, Speake C, Greenbaum CJ, Kwok WW, Baker RL, Haskins K, James EA. Hybrid Insulin Peptides are Recognized by Human T Cells in the Context of DRB1*04:01. Diabetes. PMID 32291282 DOI: 10.2337/Db19-0620  0.558
2019 Dirice E, Kahraman S, De Jesus DF, El Ouaamari A, Basile G, Baker RL, Yigit B, Piehowski PD, Kim MJ, Dwyer AJ, Ng RWS, Schuster C, Vethe H, Martinov T, Ishikawa Y, ... ... Haskins K, et al. Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes. Nature Metabolism. 1: 509-518. PMID 31423480 DOI: 10.1038/s42255-019-0061-8  0.474
2019 Baker RL, Rihanek M, Hohenstein AC, Nakayama M, Michels A, Gottlieb PA, Haskins K, Delong T. Hybrid Insulin Peptides are Autoantigens in Type 1 Diabetes. Diabetes. PMID 31175101 DOI: 10.2337/Db19-0128  0.58
2019 Baker RL, Jamison BL, Haskins K. Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 31166225 DOI: 10.1097/Med.0000000000000490  0.521
2019 Jamison BL, Neef T, Goodspeed A, Bradley B, Baker RL, Miller SD, Haskins K. Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31109955 DOI: 10.4049/Jimmunol.1900127  0.643
2019 Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS. CD11c Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. Frontiers in Immunology. 10: 99. PMID 30766536 DOI: 10.3389/Fimmu.2019.00099  0.659
2018 Wiles TA, Powell R, Michel CR, Beard KS, Hohenstein A, Bradley B, Reisdorph N, Haskins K, Delong T. Identification of hybrid insulin peptides (HIPs) in mouse and human islets by mass spectrometry. Journal of Proteome Research. PMID 30585061 DOI: 10.1021/Acs.Jproteome.8B00875  0.403
2018 Jamison BL, Haskins K. Tissue Crosstalk in T1D: Is Insulin Special? Immunity. 49: 394-396. PMID 30231981 DOI: 10.1016/J.Immuni.2018.09.001  0.369
2018 Baker RL, Jamison BL, Wiles TA, Lindsay RS, Barbour G, Bradley B, Delong T, Friedman RS, Nakayama M, Haskins K. CD4 T Cells Reactive to Hybrid Insulin Peptides are Indicators of Disease Activity in the NOD Mouse. Diabetes. PMID 29976617 DOI: 10.2337/Db18-0200  0.611
2018 BAKER RL, DELONG T, GOTTLIEB P, HASKINS KM. Characterization of T Cells Reactive to Hybrid Insulin Peptides in the Peripheral Blood of in Type 1 Diabetes Patients Diabetes. 67: 98-OR. DOI: 10.2337/db18-98-OR  0.414
2017 Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, ... ... Haskins K, et al. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. 23: 1004. PMID 28777787 DOI: 10.1038/nm0817-1004a  0.482
2017 Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, ... ... Haskins K, et al. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. 23: 264. PMID 28170374 DOI: 10.1038/Nm0217-264A  0.564
2016 Haskins K, Buckner JH. Editorial overview: Autoimmunity. Current Opinion in Immunology. PMID 27839940 DOI: 10.1016/J.Coi.2016.10.002  0.325
2016 Wiles TA, Delong T, Baker RL, Bradley B, Barbour G, Powell RL, Reisdorph N, Haskins K. An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse. Journal of Autoimmunity. PMID 27802879 DOI: 10.1016/J.Jaut.2016.10.007  0.546
2016 Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, ... ... Haskins K, et al. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. PMID 27798614 DOI: 10.1038/Nm.4203  0.662
2016 Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, ... ... Haskins K, et al. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science (New York, N.Y.). 351: 711-4. PMID 26912858 DOI: 10.1126/Science.Aad2791  0.645
2015 Baker RL, Bradley B, Wiles TA, Lindsay RS, Barbour G, Delong T, Friedman RS, Haskins K. Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes. Journal of Immunology (Baltimore, Md. : 1950). PMID 26608914 DOI: 10.4049/Jimmunol.1501190  0.664
2015 Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S. The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens. Journal of Immunology (Baltimore, Md. : 1950). 195: 1964-73. PMID 26209627 DOI: 10.4049/Jimmunol.1401683  0.591
2015 Lindsay RS, Corbin K, Mahne A, Levitt BE, Gebert MJ, Wigton EJ, Bradley BJ, Haskins K, Jacobelli J, Tang Q, Krummel MF, Friedman RS. Antigen recognition in the islets changes with progression of autoimmune islet infiltration. Journal of Immunology (Baltimore, Md. : 1950). 194: 522-30. PMID 25505281 DOI: 10.4049/Jimmunol.1400626  0.615
2014 Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K. Chromogranin A is a T cell antigen in human type 1 diabetes. Journal of Autoimmunity. 50: 38-41. PMID 24239002 DOI: 10.1016/J.Jaut.2013.10.003  0.559
2013 Baker RL, Delong T, Barbour G, Bradley B, Nakayama M, Haskins K. Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 3990-4. PMID 24043895 DOI: 10.4049/Jimmunol.1301480  0.671
2013 Cordova KN, Willis VC, Haskins K, Holers VM. A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis. Journal of Immunology (Baltimore, Md. : 1950). 190: 1457-65. PMID 23319740 DOI: 10.4049/Jimmunol.1201517  0.524
2013 Delong T, Baker RL, He J, Haskins K. Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes. Immunologic Research. 55: 167-72. PMID 22971988 DOI: 10.1007/S12026-012-8375-6  0.673
2012 Delong T, Baker RL, He J, Barbour G, Bradley B, Haskins K. Diabetogenic T-cell clones recognize an altered peptide of chromogranin A. Diabetes. 61: 3239-46. PMID 22912420 DOI: 10.2337/Db12-0112  0.639
2012 Baker RL, Mallevaey T, Gapin L, Haskins K. T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes. European Journal of Immunology. 42: 672-80. PMID 22488364 DOI: 10.1002/Eji.201142071  0.562
2012 Hume PS, He J, Haskins K, Anseth KS. Strategies to reduce dendritic cell activation through functional biomaterial design. Biomaterials. 33: 3615-25. PMID 22361099 DOI: 10.1016/J.Biomaterials.2012.02.009  0.445
2012 Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS. Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes. 61: 857-65. PMID 22315318 DOI: 10.2337/Db11-1113  0.431
2011 Haskins K, Cooke A. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes. Current Opinion in Immunology. 23: 739-45. PMID 21917439 DOI: 10.1016/J.Coi.2011.08.004  0.579
2011 Delong T, Baker RL, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Barbour G, Bradley B, Haskins K. Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells. Diabetes. 60: 2325-30. PMID 21734016 DOI: 10.2337/Db11-0288  0.597
2011 Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC. Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus. The Journal of Surgical Research. 168: e195-202. PMID 21470634 DOI: 10.1016/J.Jss.2011.01.021  0.435
2010 Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nature Immunology. 11: 225-31. PMID 20139986 DOI: 10.1038/Ni.1844  0.593
2009 Tonkin DR, Haskins K. Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner. European Journal of Immunology. 39: 1313-22. PMID 19404982 DOI: 10.1002/Eji.200838916  0.828
2009 Zhang L, Jasinski JM, Kobayashi M, Davenport B, Johnson K, Davidson H, Nakayama M, Haskins K, Eisenbarth GS. Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains. Journal of Autoimmunity. 33: 42-9. PMID 19286348 DOI: 10.1016/J.Jaut.2009.02.003  0.445
2009 Dai Y, Marrero I, Li Y, Wilson D, Haskins K, Sercarz E. OR.89. C-terminus of GAD65 is Capable of Inducing Diabetic Effector T Cells After Processing and Presentation of Apoptotic Islet Beta Cells in NOD Mice Clinical Immunology. 131: S37. DOI: 10.1016/J.Clim.2009.03.104  0.599
2009 Nakayama M, Castoe T, Jasinski J, He X, Johnson K, Haskins K, Pollock D, Vignali D, Eisenbarth G. OR.66. Pathogenic T Cell Receptor Valpha Germline Sequence Targeting Primary Peptide Insulin B:9-23 Clinical Immunology. 131: S28. DOI: 10.1016/J.Clim.2009.03.078  0.405
2008 Baker RL, Wagner DH, Haskins K. CD40 on NOD CD4 T cells contributes to their activation and pathogenicity. Journal of Autoimmunity. 31: 385-92. PMID 18951762 DOI: 10.1016/J.Jaut.2008.09.001  0.535
2008 Tonkin DR, He J, Barbour G, Haskins K. Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo. Journal of Immunology (Baltimore, Md. : 1950). 181: 4516-22. PMID 18802054 DOI: 10.4049/Jimmunol.181.7.4516  0.828
2008 Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes. 57: 1321-30. PMID 18299317 DOI: 10.2337/Db07-1129  0.627
2008 He J, Haskins K. Pathogenicity of T helper 2 T-cell clones from T-cell receptor transgenic non-obese diabetic mice is determined by tumour necrosis factor-alpha. Immunology. 123: 108-17. PMID 17983440 DOI: 10.1111/J.1365-2567.2007.02715.X  0.597
2007 Cantor J, Haskins K. Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1. Journal of Immunology (Baltimore, Md. : 1950). 179: 5760-7. PMID 17947648 DOI: 10.4049/Jimmunol.179.9.5760  0.79
2007 Nicolls MR, Haskins K, Flores SC. Oxidant stress, immune dysregulation, and vascular function in type I diabetes. Antioxidants & Redox Signaling. 9: 879-89. PMID 17508913 DOI: 10.1089/Ars.2007.1631  0.381
2007 Weber LM, Hayda KN, Haskins K, Anseth KS. The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials. 28: 3004-11. PMID 17391752 DOI: 10.1016/J.Biomaterials.2007.03.005  0.361
2007 Baker R, Wagner D, Haskins K. Regulation of Pathogenicity Through CD40 Expressed on CD4 T Cells Clinical Immunology. 123: S25. DOI: 10.1016/J.Clim.2007.03.238  0.474
2007 Tonkin D, Bradley B, Barbour G, Haskins K. TGF-β-induced TCR-Tg/NOD Regulatory T Cells Suppress Both Diabetes Transfer and Islet Graft Destruction in an Antigen-dependent Manner Clinical Immunology. 123: S4-S5. DOI: 10.1016/J.Clim.2007.03.184  0.811
2006 Weber LM, He J, Bradley B, Haskins K, Anseth KS. PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomaterialia. 2: 1-8. PMID 16701853 DOI: 10.1016/J.Actbio.2005.10.005  0.376
2006 Quinn A, McInerney M, Huffman D, McInerney B, Mayo S, Haskins K, Sercarz E. T cells to a dominant epitope of GAD65 express a public CDR3 motif. International Immunology. 18: 967-79. PMID 16641112 DOI: 10.1093/Intimm/Dxl033  0.617
2006 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. Journal of Immunology (Baltimore, Md. : 1950). 176: 2683-90. PMID 16493022 DOI: 10.1016/0092-8674(83)90232-5  0.337
2006 Cantor J, Haskins K. Interactions of macrophages and T cells in autoimmune diabetes Drug Discovery Today: Disease Mechanisms. 3: 381-385. DOI: 10.1016/J.Ddmec.2006.09.009  0.774
2006 He J, Haskins K. Su.41. Th2 T-Cell Clones from Tcr Transgenic Mice Are Diabetogenic Clinical Immunology. 119: S173-S174. DOI: 10.1016/J.Clim.2006.04.468  0.552
2006 Baker R, Wagner D, Haskins K. Su.33. Cd40 Is Expressed On a Subpopulation of Cd4hi T-Cells from Nod Mice Clinical Immunology. 119: S171. DOI: 10.1016/J.Clim.2006.04.460  0.561
2006 Tonkin D, Haskins K. Su.29. Tgfβ-Induced Tregs from a Tcr-Tg Nod Suppress Th1 Cytokines and Macrophage Recruitment in the Pancreas Clinical Immunology. 119: S169-S170. DOI: 10.1016/J.Clim.2006.04.456  0.762
2006 Cantor J, Haskins K. OR.30. Recruitment and Activation of Macrophages in the Pancreas After Adoptive Transfer By Diabetogenic CD4 Th1 T-Cells Involves Interaction of CCL1 and CCR8 Clinical Immunology. 119: S15. DOI: 10.1016/J.Clim.2006.04.032  0.745
2005 Phillips JM, Haskins K, Cooke A. MAdCAM-1 is needed for diabetes development mediated by the T cell clone, BDC-2.5. Immunology. 116: 525-31. PMID 16313366 DOI: 10.1111/J.1365-2567.2005.02254.X  0.581
2005 Cantor J, Haskins K. Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha. Journal of Immunology (Baltimore, Md. : 1950). 175: 7738-45. PMID 16301684 DOI: 10.4049/Jimmunol.175.11.7738  0.789
2005 Ling X, Cota-Gomez A, Flores NC, Hernandez-Saavedra D, McCord JM, Marecki JC, Haskins K, McDuffie M, Powers K, Kench J, Oka M, McMurtry I, Flores SC. Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. Free Radical Biology & Medicine. 39: 1089-98. PMID 16198235 DOI: 10.1016/J.Freeradbiomed.2005.05.027  0.353
2005 Haskins K. Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse. Advances in Immunology. 87: 123-62. PMID 16102573 DOI: 10.1016/S0065-2776(05)87004-X  0.636
2004 Pauza ME, Dobbs CM, He J, Patterson T, Wagner S, Anobile BS, Bradley BJ, Lo D, Haskins K. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes. 53: 978-88. PMID 15047613 DOI: 10.2337/Diabetes.53.4.978  0.63
2004 Haskins K, Kench J, Powers K, Bradley B, Pugazhenthi S, Reusch J, McDuffie M. Role for oxidative stress in the regeneration of islet beta cells? Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 52: 45-9. PMID 14989369 DOI: 10.1136/jim-52-01-25  0.356
2004 Haskins K. T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones. Journal of Autoimmunity. 22: 107-9. PMID 14987737 DOI: 10.1016/J.Jaut.2003.10.006  0.619
2003 Haskins K, Bradley B, Powers K, Fadok V, Flores S, Ling X, Pugazhenthi S, Reusch J, Kench J. Oxidative stress in type 1 diabetes. Annals of the New York Academy of Sciences. 1005: 43-54. PMID 14679039 DOI: 10.1196/Annals.1288.006  0.384
2003 Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. The Journal of Clinical Investigation. 112: 902-14. PMID 12975475 DOI: 10.1172/Jci18337  0.622
2003 Roberts SA, Barbour G, Matarrese MR, Mason DL, Leiter EH, Haskins K, Hanson MS. Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells. Journal of Autoimmunity. 21: 139-47. PMID 12935783 DOI: 10.1016/S0896-8411(03)00090-8  0.62
2003 Vaitaitis GM, Poulin M, Sanderson RJ, Haskins K, Wagner DH. Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery. Journal of Immunology (Baltimore, Md. : 1950). 170: 3455-9. PMID 12646605 DOI: 10.4049/Jimmunol.170.7.3455  0.804
2002 Yoshida K, Martin T, Yamamoto K, Dobbs C, Münz C, Kamikawaji N, Nakano N, Rammensee HG, Sasazuki T, Haskins K, Kikutani H. Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones. International Immunology. 14: 1439-47. PMID 12456592 DOI: 10.1093/Intimm/Dxf106  0.574
2002 Wagner DH, Vaitaitis G, Sanderson R, Poulin M, Dobbs C, Haskins K. Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 99: 3782-7. PMID 11891296 DOI: 10.1073/Pnas.052247099  0.816
2002 Piganelli JD, Flores SC, Cruz C, Koepp J, Batinic-Haberle I, Crapo J, Day B, Kachadourian R, Young R, Bradley B, Haskins K. A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. Diabetes. 51: 347-55. PMID 11812741 DOI: 10.2337/Diabetes.51.2.347  0.615
2001 Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, Von Herrath M, Wegmann D, Wen L, Zekzer D. Report from the 1st International NOD Mouse T-Cell Workshop and the Follow-Up Mini-Workshop Diabetes. 50: 2459-2463. PMID 11679422 DOI: 10.2337/Diabetes.50.11.2459  0.547
2001 Haskins K, Atkinson M. Prediction of diabetes and response to therapy in individual animals: Are there lessons for man? Report on the JDF/Snow Mountain meeting, 5-7 October 2000, Winter Park, CO, USA Journal of Autoimmunity. 16: 15-19. PMID 11221992 DOI: 10.1006/Jaut.2000.0467  0.329
2001 Dobbs CM, Haskins K. Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical Journal of Immunology. 166: 2495-2504. PMID 11160310 DOI: 10.4049/Jimmunol.166.4.2495  0.671
2000 Phillips JM, Harach SZ, Parish NM, Fehervari Z, Haskins K, Cooke A. Nondepleting anti-CD4 has an immediate action on diabetogenic effector cells, halting their destruction of pancreatic beta cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 1949-55. PMID 10925277 DOI: 10.4049/Jimmunol.165.4.1949  0.57
2000 Tree TIM, O'Byrne D, Tremble JM, MacFarlane WM, Haskins K, James RFL, Docherty K, Hutton JC, Banga JP. Evidence for recognition of novel islet T cell antigens by granule- specific T cell lines from new onset type 1 diabetic patients Clinical and Experimental Immunology. 121: 100-105. PMID 10886245 DOI: 10.1046/J.1365-2249.2000.01279.X  0.597
2000 Bergman B, McManaman JL, Haskins K. Biochemical characterization of a beta cell membrane fraction antigenic for autoreactive T cell clones Journal of Autoimmunity. 14: 343-351. PMID 10882061 DOI: 10.1006/Jaut.2000.0377  0.458
2000 Poulin M, Haskins K. Induction of diabetes in nonobese diabetic mice by Th2 T cell clones from a TCR transgenic mouse Journal of Immunology. 164: 3072-3078. PMID 10706696 DOI: 10.4049/Jimmunol.164.6.3072  0.834
2000 Piganelli JD, Poulin M, Martin T, Allison JP, Haskins K. Cytotoxic T lymphocyte antigen 4 (CD152)regulates self-reactive T cells in BALB/c but not in the autoimmune nod mouse Journal of Autoimmunity. 14: 123-131. PMID 10677243 DOI: 10.1006/Jaut.1999.0353  0.808
2000 Rosmalen JGM, Martin T, Dobbs C, Voerman JSA, Drexhage HA, Haskins K, Leenen PJM. Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: Correlation with the development of diabetes Laboratory Investigation. 80: 23-30. PMID 10652999 DOI: 10.1038/Labinvest.3780004  0.632
1999 Haskins K. T cell receptor gene usage in autoimmune diabetes International Reviews of Immunology. 18: 61-81. PMID 10614739 DOI: 10.3109/08830189909043019  0.567
1999 Fossati G, Cooke A, Papafio RQ, Haskins K, Stockinger B. Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes Journal of Experimental Medicine. 190: 577-583. PMID 10449528 DOI: 10.1084/Jem.190.4.577  0.597
1999 Zaccone P, Phillips J, Conget I, Gomis R, Haskins K, Minty A, Bendtzen K, Cooke A, Nicoletti F. Interleukin-13 prevents autoimmune diabetes in NOD mice Diabetes. 48: 1522-1528. PMID 10426368 DOI: 10.2337/Diabetes.48.8.1522  0.521
1999 Crawford M, Haskins K, Gill RG. FAS (CD95)-INDEPENDENT ISLET ALLOGRAFT DESTRUCTION MEDIATED BY CD4+ ISLET-SPECIFIC T CELLS Transplantation. 67: S36. DOI: 10.1097/00007890-199904150-00148  0.52
1998 Peterson JD, Berg R, Piganelli JD, Poulin M, Haskins K. Analysis of leukocytes recruited to the pancreas by diabetogenic T cell clones. Cellular Immunology. 189: 92-8. PMID 9790722 DOI: 10.1006/Cimm.1998.1377  0.829
1998 Piganelli JD, Martin T, Haskins K. Splenic macrophages from the NOD mouse are defective in the ability to present antigen Diabetes. 47: 1212-1218. PMID 9703319 DOI: 10.2337/Diab.47.8.1212  0.621
1998 Haskins K, Poulin M, Dobbs C. Th2 T cell clones from a TCR transgenic NOD mouse Faseb Journal. 12.  0.531
1998 Piganelli JD, Poulin M, Martin T, Allison JP, Haskins K. Lack of regulation by CTLA-4 in the autoimmune NOD mouse Faseb Journal. 12.  0.533
1997 McKeever U, Khandekar S, Jesson M, Newcomb J, Gregory P, Naylor J, Haskins K, Jones B. Maternal Immunization with a Soluble TCR-Ig Chimeric Protein: Long Term, Vβ-8 Family-Specific Suppression of T Cells by Maternally Transferred Antibodies Journal of Immunology. 159: 5936-5945. PMID 9550391  0.515
1997 Bergman B, Haskins K. Autoreactive T-cell clones from the nonobese diabetic mouse Proceedings of the Society For Experimental Biology and Medicine. 214: 41-48. PMID 9012359 DOI: 10.3181/00379727-214-44067  0.675
1997 Ferguson PJ, Poulin M, Haskins K, McDuffie MJ. Genetic control of resistance to insulin-dependent diabetes in NOD mice.• 382 Pediatric Research. 41: 66-66. DOI: 10.1203/00006450-199704001-00402  0.733
1996 McKeever U, Khandekar S, Newcomb J, Naylor J, Gregory P, Brauer P, Jesson M, Bettencourt B, Burke E, Alderson A, Banerji J, Haskins K, Jones B. Immunization with soluble BDC 2.5 T cell receptor-immunoglobulin chimeric protein:antibody specificity and protection of nonobese diabetic mice against adoptive transfer of diabetes by maternal immunization. The Journal of Experimental Medicine. 184: 1755-68. PMID 8920864 DOI: 10.1084/Jem.184.5.1755  0.62
1996 Haskins K, Wegmann D. Diabetogenic T-cell clones. Diabetes. 45: 1299-305. PMID 8826963 DOI: 10.2337/Diab.45.10.1299  0.653
1996 Peterson JD, Haskins K. Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells. Diabetes. 45: 328-36. PMID 8593938 DOI: 10.2337/Diab.45.3.328  0.654
1995 Dallas-Pedretti A, Mcduffie M, Haskins K. A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6 Proceedings of the National Academy of Sciences of the United States of America. 92: 1386-1390. PMID 7877988 DOI: 10.1073/Pnas.92.5.1386  0.589
1995 Peterson JD, Haskins K. Immunotherapy of animal models of insulin-dependent diabetes mellitus Current Opinion in Endocrinology and Diabetes. 2: 17-23. DOI: 10.1097/00060793-199502000-00004  0.401
1994 Bergman B, Haskins K. Islet-specific T-cell clones from the NOD mouse respond to β-granule antigen Diabetes. 43: 197-203. PMID 8288043  0.423
1994 Peterson JD, Pike B, McDuffie M, Haskins K. Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) F1 mice. Journal of Immunology (Baltimore, Md. : 1950). 153: 2800-6. PMID 8077683  0.466
1993 Katz JD, Wang B, Haskins K, Benoist C, Mathis D. Following a diabetogenic T cell from genesis through pathogenesis. Cell. 74: 1089-100. PMID 8402882 DOI: 10.1016/0092-8674(93)90730-E  0.609
1992 Bradley BJ, Haskins K, La Rosa FG, Lafferty KJ. CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone Diabetes. 41: 1603-1608. PMID 1446802 DOI: 10.2337/Diab.41.12.1603  0.662
1992 Wegmann D, Norbury-Glaser M, Bergman B, Haskins K. High efficiency presentation of TNP-conjugated islet antigen to islet- specific T cells by a hybrid B cell line expressing TNP-specific surface Ig Journal of Immunology. 149: 77-82. PMID 1318906  0.552
1991 Candeias S, Katz J, Benoist C, Mathis D, Haskins K. Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors Proceedings of the National Academy of Sciences of the United States of America. 88: 6167-6170. PMID 2068098 DOI: 10.1073/Pnas.88.14.6167  0.643
1990 Supon P, Stecha P, Haskins K. Anti-islet cell antibodies from NOD mice Diabetes. 39: 1366-1372. PMID 2227111 DOI: 10.2337/Diab.39.11.1366  0.415
1990 Haskins K, Mcduffie M. Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone Science. 249: 1433-1436. PMID 2205920 DOI: 10.1126/Science.2205920  0.594
1990 Bradley BJ, Wang Y, Lafferty KJ, Haskins K. In vivo activity of an islet-reactive T-cell clone Journal of Autoimmunity. 3: 449-456. PMID 1977404 DOI: 10.1016/S0896-8411(05)80012-5  0.571
1989 Haskins K, Portas M, Bergman B, Lafferty K, Bradley B. Pancreatic islet-specific T-cell clones from nonobese diabetic mice Proceedings of the National Academy of Sciences of the United States of America. 86: 8000-8004. PMID 2510155 DOI: 10.1073/Pnas.86.20.8000  0.597
1989 Bohme J, Haskins K, Stecha P, Van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant Science. 244: 1179-183. PMID 2499048 DOI: 10.1126/Science.2499048  0.48
1988 Haskins K, Portas M, Bradley B, Wegmann D, Lafferty K. T-lymphocyte clone specific for pancreatic islet antigen Diabetes. 37: 1444-1448. PMID 2458291 DOI: 10.2337/Diab.37.10.1444  0.589
1987 Kubo RT, Haskins K, Shu Man Fu. Serologic identification of the murine T3 homologue by cross-reactive xenogeneic anti-human T3 antisera Molecular Immunology. 24: 201-204. PMID 2956499 DOI: 10.1016/0161-5890(87)90093-9  0.404
1985 Haskins K. The T-cell receptor for antigen The Year in Immunology. 74-79. PMID 3879908  0.416
1984 Roehm N, Herron L, Cambier J, Diguisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells Cell. 38: 577-584. PMID 6331891 DOI: 10.1016/0092-8674(84)90512-9  0.508
1984 Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype Journal of Experimental Medicine. 160: 452-471. PMID 6206178 DOI: 10.1084/Jem.160.2.452  0.476
1984 Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells Annual Review of Immunology. 2: 51-66. PMID 6085752 DOI: 10.1146/Annurev.Iy.02.040184.000411  0.487
1983 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 35: 295-302. PMID 6605199 DOI: 10.1016/0092-8674(83)90232-5  0.483
1983 Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas Cell. 34: 727-737. PMID 6605198 DOI: 10.1016/0092-8674(83)90529-9  0.433
1983 Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody Journal of Experimental Medicine. 157: 1149-1169. PMID 6601175 DOI: 10.1084/Jem.157.4.1149  0.512
1983 Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunological Reviews. 76: 131-45. PMID 6363275 DOI: 10.1111/J.1600-065X.1983.Tb01100.X  0.414
1983 Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity Journal of Experimental Medicine. 158: 1635-1646. PMID 6195288 DOI: 10.1084/Jem.158.5.1635  0.467
1983 White J, Haskins KM, Marrack P, Kappler J. Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies Journal of Immunology. 130: 1033-1037. PMID 6185566  0.365
Show low-probability matches.