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John W. Kappler - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Biochemistry, Immunology
Website:
https://www.nationaljewish.org/doctors-departments/providers/researchers/john-w-kappler
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175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ramos SA, Morton JJ, Yadav P, Reed B, Alizadeh SI, Shilleh AH, Perrenoud L, Jaggers J, Kappler J, Jimeno A, Russ HA. Generation of functional human thymic cells from induced pluripotent stem cells. The Journal of Allergy and Clinical Immunology. PMID 34331993 DOI: 10.1016/j.jaci.2021.07.021  0.354
2021 Reed BK, Kappler JW. Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes. Frontiers in Immunology. 12: 669986. PMID 33986758 DOI: 10.3389/fimmu.2021.669986  0.469
2021 Falta MT, Crawford JC, Tinega AN, Landry LG, Crawford F, Mack DG, Martin AK, Atif SM, Li L, Santos RG, Nakayama M, Kappler JW, Maier LA, Thomas PG, Pinilla C, et al. Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation. The Journal of Clinical Investigation. PMID 33630763 DOI: 10.1172/JCI144864  0.46
2021 Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine. 218. PMID 33095259 DOI: 10.1084/jem.20192135  0.43
2020 Cepeda JR, Sekhar NS, Han J, Xiong W, Zhang N, Yu L, Dai S, Davidson HW, Kappler JW, An Z, Zhang L. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. Mabs. 12: 1836714. PMID 33151102 DOI: 10.1080/19420862.2020.1836714  0.47
2020 Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MK. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. PMID 32931017 DOI: 10.1111/Imm.13263  0.362
2020 Phalke S, Aviszus K, Rubtsova K, Rubtsov A, Barkes B, Powers L, Warner B, Crooks JL, Kappler JW, Fernández-Pérez ER, Maier LA, Hamzeh N, Marrack P. Age Associated B Cells Appear in Patients with Granulomatous Lung Diseases. American Journal of Respiratory and Critical Care Medicine. PMID 32501729 DOI: 10.1164/Rccm.201911-2151Oc  0.72
2019 Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570608 DOI: 10.1073/Pnas.1909504116  0.503
2019 Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, et al. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4. PMID 30952805 DOI: 10.1126/sciimmunol.aav7517  0.499
2018 Williams T, Krovi H, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama M. Development of T cell lines sensitive to antigen stimulation. Journal of Immunological Methods. PMID 30165064 DOI: 10.1016/j.jim.2018.08.011  0.518
2018 Rozanov DV, Rozanov ND, Chiotti K, Reddy A, Wilmarth PA, David LL, Cha SW, Woo S, Pevzner P, Bafna V, Burrows GG, Rantala JK, Levin T, Anur P, Johnson-Camacho K, ... ... Kappler JW, et al. MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection. Journal of Proteomics. PMID 29331515 DOI: 10.1016/J.Jprot.2018.01.004  0.302
2017 Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255035 DOI: 10.2210/Pdb6Blx/Pdb  0.436
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of the T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor. Elife. 6. PMID 29148973 DOI: 10.7554/Elife.30918  0.456
2017 Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. The Journal of Clinical Investigation. PMID 28240602 DOI: 10.1172/Jci91250  0.774
2017 Dai S, Wang Y, Kappler J, Novikov A, Crawford F. Diabetogenic T cell recognition of an insulin antigen Acta Crystallographica Section a Foundations and Advances. 73: C519-C519. DOI: 10.1107/S2053273317090544  0.371
2016 Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Islet-derived CD4 T-cells targeting proinsulin in human autoimmune diabetes. Diabetes. PMID 27920090 DOI: 10.2337/Db16-1025  0.49
2016 Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. Plos One. 11: e0166322. PMID 27880772 DOI: 10.1371/Journal.Pone.0166322  0.773
2016 Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine αβ T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. Journal of Immunology (Baltimore, Md. : 1950). 197: 3437-3443. PMID 27824590  0.344
2016 Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, ... ... Kappler JW, et al. Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion. Immunity. 45: 917-930. PMID 27760342 DOI: 10.1016/J.Immuni.2016.09.015  0.407
2016 Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588903 DOI: 10.1073/Pnas.1609717113  0.431
2016 Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS. Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation. Journal of Immunology (Baltimore, Md. : 1950). 196: 22-7. PMID 26685315 DOI: 10.4049/jimmunol.1502011  0.344
2015 Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26453556 DOI: 10.1073/Pnas.1517862112  0.48
2015 Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4(+) T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunology. PMID 26129650 DOI: 10.1038/Mi.2015.54  0.466
2015 Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. Journal of Immunology (Baltimore, Md. : 1950). 195: 71-9. PMID 26034175 DOI: 10.4049/Jimmunol.1500055  0.779
2015 Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proceedings of the National Academy of Sciences of the United States of America. 112: 4429-34. PMID 25831495 DOI: 10.1073/Pnas.1502967112  0.465
2014 Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, et al. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science (New York, N.Y.). 346: 363-8. PMID 25324392 DOI: 10.1126/science.1259077  0.434
2014 Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 14840-5. PMID 25267644 DOI: 10.1073/Pnas.1416864111  0.522
2014 Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 158: 132-42. PMID 24995984 DOI: 10.1016/J.Cell.2014.04.048  0.486
2014 Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 8553-8. PMID 24912188 DOI: 10.1073/Pnas.1408048111  0.443
2014 Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the αβ T cell receptor. Journal of Molecular Medicine (Berlin, Germany). 92: 735-41. PMID 24848996 DOI: 10.1007/S00109-014-1145-2  0.455
2014 David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7735-40. PMID 24821788 DOI: 10.1073/Pnas.1406218111  0.454
2014 Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP. Identification of multiple public TCR repertoires in chronic beryllium disease. Journal of Immunology (Baltimore, Md. : 1950). 192: 4571-80. PMID 24719461 DOI: 10.4049/Jimmunol.1400007  0.468
2014 Zhang L, Crawford F, Yu L, Michels A, Nakayama M, Davidson HW, Kappler JW, Eisenbarth GS. Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 2656-61. PMID 24550292 DOI: 10.1073/pnas.1323436111  0.476
2014 Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proceedings of the National Academy of Sciences of the United States of America. 111: E119-28. PMID 24344267 DOI: 10.1073/Pnas.1320777110  0.458
2013 Buhrman JD, Jordan KR, Munson DJ, Moore BL, Kappler JW, Slansky JE. Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor. The Journal of Biological Chemistry. 288: 33213-25. PMID 24106273 DOI: 10.1074/Jbc.M113.509554  0.337
2013 Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proceedings of the National Academy of Sciences of the United States of America. 110: E3216-24. PMID 23922396 DOI: 10.1073/Pnas.1312348110  0.781
2013 Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. The Journal of Experimental Medicine. 210: 1403-18. PMID 23797096 DOI: 10.1084/Jem.20122426  0.506
2013 Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. Plos One. 8: e57435. PMID 23483882 DOI: 10.1371/Journal.Pone.0057435  0.666
2013 McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1122-31. PMID 23447566 DOI: 10.1073/Pnas.1300392110  0.321
2013 Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. Plos One. 8: e53789. PMID 23342002 DOI: 10.1371/Journal.Pone.0053789  0.354
2013 Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein & Cell. 4: 8-16. PMID 23307779 DOI: 10.1007/S13238-012-2077-7  0.334
2013 Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. European Journal of Immunology. 43: 521-32. PMID 23172374 DOI: 10.1002/Eji.201242757  0.664
2013 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunologic Research. 55: 210-6. PMID 22945807 DOI: 10.1007/S12026-012-8365-8  0.71
2012 Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proceedings of the National Academy of Sciences of the United States of America. 109: 18517-22. PMID 23091041 DOI: 10.1073/Pnas.1215928109  0.445
2012 Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunological Reviews. 250: 49-60. PMID 23046122 DOI: 10.1111/Imr.12004  0.436
2012 Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harbor Perspectives in Medicine. 2: a007765. PMID 22951444 DOI: 10.1101/Cshperspect.A007765  0.494
2012 Jordan KR, Buhrman JD, Sprague J, Moore BL, Gao D, Kappler JW, Slansky JE. TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines. Cancer Immunology, Immunotherapy : Cii. 61: 1627-38. PMID 22350070 DOI: 10.1007/S00262-012-1217-5  0.392
2011 Zhang L, Stadinski BD, Michels A, Kappler JW, Eisenbarth GS. Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice. Diabetes/Metabolism Research and Reviews. 27: 784-9. PMID 22069260 DOI: 10.1002/dmrr.1252  0.759
2011 Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to αβ T cell receptor specificity. Immunity. 35: 526-35. PMID 21962492 DOI: 10.1016/J.Immuni.2011.09.005  0.394
2011 Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proceedings of the National Academy of Sciences of the United States of America. 108: 16729-34. PMID 21949373 DOI: 10.1073/Pnas.1113954108  0.798
2011 Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. Journal of Immunology (Baltimore, Md. : 1950). 187: 3694-703. PMID 21873524 DOI: 10.4049/Jimmunol.1101872  0.357
2011 Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 35: 23-33. PMID 21683626 DOI: 10.1016/J.Immuni.2011.04.017  0.757
2011 Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. Blood. 118: 1305-15. PMID 21543762 DOI: 10.1182/Blood-2011-01-331462  0.752
2011 MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 2889-96. PMID 21270407 DOI: 10.4049/Jimmunol.1002955  0.379
2010 Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proceedings of the National Academy of Sciences of the United States of America. 107: 10978-83. PMID 20534455 DOI: 10.1073/Pnas.1006545107  0.784
2010 Falta MT, Bowerman NA, Dai S, Kappler JW, Fontenot AP. Linking genetic susceptibility and T cell activation in beryllium-induced disease. Proceedings of the American Thoracic Society. 7: 126-9. PMID 20427584 DOI: 10.1513/pats.201002-022RM  0.321
2010 Stadinski B, Kappler J, Eisenbarth GS. Molecular targeting of islet autoantigens. Immunity. 32: 446-56. PMID 20412755 DOI: 10.1016/j.immuni.2010.04.008  0.795
2010 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. Journal of Immunology (Baltimore, Md. : 1950). 184: 4592-5. PMID 20410496  0.313
2010 Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 7425-30. PMID 20356827 DOI: 10.1073/Pnas.1001772107  0.362
2010 MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 130: 10-5. PMID 20331469 DOI: 10.1111/J.1365-2567.2010.03260.X  0.31
2010 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmunity Reviews. 9: 494-8. PMID 20144912 DOI: 10.1016/J.Autrev.2010.02.008  0.682
2010 Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nature Immunology. 11: 225-31. PMID 20139986 DOI: 10.1038/Ni.1844  0.788
2010 Jordan KR, McMahan RH, Kemmler CB, Kappler JW, Slansky JE. Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens. Proceedings of the National Academy of Sciences of the United States of America. 107: 4652-7. PMID 20133772 DOI: 10.1073/Pnas.0914879107  0.4
2010 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in β2M, MHC class I proteins, and CD8+ T cells Journal of Immunology. 184: 1227-1230. DOI: 10.1126/science.2112266  0.354
2009 Macdonald WA, Chen Z, Gras S, Archbold JK, Tynan FE, Clements CS, Bharadwaj M, Kjer-Nielsen L, Saunders PM, Wilce MC, Crawford F, Stadinsky B, Jackson D, Brooks AG, Purcell AW, ... Kappler JW, et al. T cell allorecognition via molecular mimicry. Immunity. 31: 897-908. PMID 20064448 DOI: 10.1016/J.Immuni.2009.09.025  0.455
2009 Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. Plos Biology. 7: e1000253. PMID 19956738 DOI: 10.1371/Journal.Pbio.1000253  0.419
2009 McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 4403-14. PMID 19734227 DOI: 10.4049/Jimmunol.0900164  0.319
2009 Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proceedings of the National Academy of Sciences of the United States of America. 106: 7951-6. PMID 19416894 DOI: 10.1073/Pnas.0902728106  0.763
2009 Jordan KR, Crawford F, Kappler JW, Slansky JE. Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 2.15. PMID 19347845 DOI: 10.1002/0471142735.Im0215S85  0.304
2009 Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 458: 1043-6. PMID 19262510 DOI: 10.1038/Nature07812  0.473
2009 Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. International Immunology. 21: 339-48. PMID 19208752 DOI: 10.1093/Intimm/Dxp002  0.395
2008 Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nature Immunology. 9: 1356-63. PMID 18931680 DOI: 10.1038/Ni.1670  0.458
2008 Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proceedings of the National Academy of Sciences of the United States of America. 105: 12997-3002. PMID 18728183 DOI: 10.1073/Pnas.0805465105  0.314
2008 Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proceedings of the National Academy of Sciences of the United States of America. 105: 11893-7. PMID 18697946 DOI: 10.1073/Pnas.0805810105  0.416
2008 Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Current Opinion in Immunology. 20: 203-7. PMID 18456484 DOI: 10.1016/J.Coi.2008.03.008  0.785
2008 McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. International Immunology. 20: 659-69. PMID 18343889 DOI: 10.1093/Intimm/Dxn025  0.387
2008 Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 28: 324-34. PMID 18308592 DOI: 10.1016/J.Immuni.2008.01.008  0.775
2008 Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annual Review of Immunology. 26: 171-203. PMID 18304006 DOI: 10.1146/Annurev.Immunol.26.021607.090421  0.41
2008 Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE. Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity. Journal of Immunology (Baltimore, Md. : 1950). 180: 188-97. PMID 18097019 DOI: 10.4049/Jimmunol.180.1.188  0.362
2008 Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Molecular Immunology. 45: 599-606. PMID 17920446 DOI: 10.1016/J.Molimm.2006.03.025  0.379
2007 Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. The Journal of Clinical Investigation. 117: 1270-81. PMID 17476359 DOI: 10.1172/Jci30513  0.342
2007 Clambey ET, Kappler JW, Marrack P. CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome. Experimental Gerontology. 42: 407-11. PMID 17197145 DOI: 10.1016/J.Exger.2006.11.008  0.34
2006 Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. The Journal of Experimental Medicine. 203: 2953-61. PMID 17158961 DOI: 10.1084/Jem.20061151  0.304
2006 Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 25: 929-40. PMID 17137798 DOI: 10.1016/J.Immuni.2006.10.012  0.402
2006 Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nature Immunology. 7: 1191-9. PMID 17041605 DOI: 10.1038/Ni1401  0.409
2006 Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proceedings of the National Academy of Sciences of the United States of America. 103: 12063-8. PMID 16880405 DOI: 10.1073/pnas.0605130103  0.504
2006 Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunological Reviews. 211: 49-57. PMID 16824116 DOI: 10.1111/J.0105-2896.2006.00383.X  0.32
2006 Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. The Journal of Experimental Medicine. 203: 1147-52. PMID 16651384 DOI: 10.1084/Jem.20051736  0.446
2006 Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunological Reviews. 210: 156-70. PMID 16623770 DOI: 10.1111/J.0105-2896.2006.00365.X  0.771
2006 Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. The Journal of Experimental Medicine. 203: 731-41. PMID 16520387 DOI: 10.1084/Jem.20051407  0.4
2006 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. Journal of Immunology (Baltimore, Md. : 1950). 176: 2683-90. PMID 16493022 DOI: 10.1016/0092-8674(83)90232-5  0.47
2006 Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. International Archives of Allergy and Immunology. 139: 63-74. PMID 16319493 DOI: 10.1159/000090000  0.321
2005 Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 122: 247-60. PMID 16051149 DOI: 10.1016/J.Cell.2005.05.013  0.505
2005 Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis and Rheumatism. 52: 1885-96. PMID 15934080 DOI: 10.1002/Art.21098  0.471
2005 Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunological Reviews. 205: 170-89. PMID 15882353 DOI: 10.1111/J.0105-2896.2005.00265.X  0.315
2005 Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proceedings of the National Academy of Sciences of the United States of America. 102: 2476-81. PMID 15699351 DOI: 10.1073/Pnas.0409798102  0.447
2004 Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science (New York, N.Y.). 304: 1808-10. PMID 15205534 DOI: 10.1126/Science.1089926  0.344
2004 Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7681-6. PMID 15136728 DOI: 10.1073/Pnas.0402293101  0.333
2004 Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. Plos Biology. 2: E90. PMID 15094798 DOI: 10.1371/Journal.Pbio.0020090  0.416
2004 Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 104: 735-43. PMID 15069016 DOI: 10.1182/Blood-2003-10-3413  0.317
2004 Marrack P, Kappler J. Control of T cell viability. Annual Review of Immunology. 22: 765-87. PMID 15032596 DOI: 10.1146/Annurev.Immunol.22.012703.104554  0.4
2004 Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1004-9. PMID 14724296 DOI: 10.1073/Pnas.0307858100  0.303
2003 Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 100: 15035-40. PMID 14657380 DOI: 10.1073/Pnas.1936213100  0.353
2003 Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proceedings of the National Academy of Sciences of the United States of America. 100: 11565-70. PMID 14504410 DOI: 10.1073/Pnas.1934636100  0.484
2003 Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nature Immunology. 4: 974-81. PMID 12949532 DOI: 10.1038/Ni971  0.384
2003 Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. The Journal of Clinical Investigation. 111: 575-81. PMID 12618509 DOI: 10.1172/Jci18007  0.368
2003 Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. The Journal of Experimental Medicine. 197: 567-74. PMID 12615898 DOI: 10.1084/Jem.20021762  0.794
2003 Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Current Opinion in Immunology. 15: 120-7. PMID 12495743 DOI: 10.1016/S0952-7915(02)00009-2  0.423
2002 Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Annals of the New York Academy of Sciences. 975: 114-31. PMID 12538159 DOI: 10.1111/J.1749-6632.2002.Tb05946.X  0.357
2002 Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 17: 605-15. PMID 12433367 DOI: 10.1016/S1074-7613(02)00456-9  0.315
2002 de Souza AR, Swanson B, Robertson J, Bender J, Kappler J, Marrack P. Some properties of T cells in animals. Advances in Experimental Medicine and Biology. 512: 121-8. PMID 12405195 DOI: 10.1007/978-1-4615-0757-4_16  0.4
2002 Freiberg BA, Kupfer H, Maslanik W, Delli J, Kappler J, Zaller DM, Kupfer A. Staging and resetting T cell activation in SMACs. Nature Immunology. 3: 911-7. PMID 12244310 DOI: 10.1038/Ni836  0.415
2002 Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 16: 759-67. PMID 12121658 DOI: 10.1016/S1074-7613(02)00322-9  0.423
2002 Liu X, Dai S, Crawford F, Fruge R, Marrack P, Kappler J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proceedings of the National Academy of Sciences of the United States of America. 99: 8820-5. PMID 12084926 DOI: 10.1073/Pnas.132272099  0.324
2002 Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Current Opinion in Immunology. 14: 354-9. PMID 11973134 DOI: 10.1016/S0952-7915(02)00335-7  0.35
2002 Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). The Journal of Experimental Medicine. 195: 1043-52. PMID 11956295 DOI: 10.1084/Jem.20011971  0.356
2002 Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nature Immunology. 3: 27-32. PMID 11731800 DOI: 10.1038/Ni742  0.524
2001 Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nature Immunology. 2: 397-402. PMID 11323692 DOI: 10.1038/87692  0.376
2001 Lang P, Stolpa JC, Freiberg BA, Crawford F, Kappler J, Kupfer A, Cambier JC. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science (New York, N.Y.). 291: 1537-40. PMID 11222857 DOI: 10.1126/Science.291.5508.1537  0.348
2000 Fassò M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. The Journal of Experimental Medicine. 192: 1719-30. PMID 11120769 DOI: 10.1084/Jem.192.12.1719  0.443
2000 Kedl RM, Rees WA, Hildeman DA, Schaefer B, Mitchell T, Kappler J, Marrack P. T cells compete for access to antigen-bearing antigen-presenting cells. The Journal of Experimental Medicine. 192: 1105-13. PMID 11034600 DOI: 10.1084/Jem.192.8.1105  0.51
1999 Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America. 96: 9781-6. PMID 10449771 DOI: 10.1073/Pnas.96.17.9781  0.505
1999 Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. The Journal of Experimental Medicine. 190: 367-74. PMID 10430625 DOI: 10.1084/Jem.190.3.367  0.49
1999 Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. The Journal of Experimental Medicine. 189: 521-30. PMID 9927514 DOI: 10.1084/Jem.189.3.521  0.319
1998 Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 8: 675-82. PMID 9655481 DOI: 10.1016/S1074-7613(00)80572-5  0.533
1998 Liu CP, Crawford F, Marrack P, Kappler J. T cell positive selection by a high density, low affinity ligand. Proceedings of the National Academy of Sciences of the United States of America. 95: 4522-6. PMID 9539770 DOI: 10.1073/Pnas.95.8.4522  0.479
1998 Ku CC, Kotzin B, Kappler J, Marrack P. CD8+ T-cell clones in old mice. Immunological Reviews. 160: 139-44. PMID 9476672 DOI: 10.1111/J.1600-065X.1997.Tb01034.X  0.319
1997 Seibel JL, Wilson N, Kozono H, Marrack P, Kappler JW. Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition. The Journal of Experimental Medicine. 185: 1919-27. PMID 9166421 DOI: 10.1084/Jem.185.11.1919  0.422
1996 Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. The Journal of Experimental Medicine. 184: 1619-30. PMID 8920852 DOI: 10.1084/Jem.184.5.1619  0.303
1996 Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 84: 521-9. PMID 8598039 DOI: 10.1016/S0092-8674(00)81028-4  0.428
1995 Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 3: 187-96. PMID 7648392 DOI: 10.1016/1074-7613(95)90088-8  0.305
1995 Scherer MT, Ignatowicz L, Pullen A, Kappler J, Marrack P. The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. The Journal of Experimental Medicine. 182: 1493-504. PMID 7595219 DOI: 10.1084/Jem.182.5.1493  0.373
1995 Vella AT, McCormack JE, Linsley PS, Kappler JW, Marrack P. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity. 2: 261-70. PMID 7535182 DOI: 10.1016/1074-7613(95)90050-0  0.44
1994 Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 369: 151-4. PMID 8177320 DOI: 10.1038/369151A0  0.438
1994 Kappler J, White J, Kozono H, Clements J, Marrack P. Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proceedings of the National Academy of Sciences of the United States of America. 91: 8462-6. PMID 8078904 DOI: 10.1073/Pnas.91.18.8462  0.39
1994 Hamad AR, Herman A, Marrack P, Kappler JW. Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B. The Journal of Experimental Medicine. 180: 615-21. PMID 7519243 DOI: 10.1084/Jem.180.2.615  0.419
1993 Kotzin BL, Leung DY, Kappler J, Marrack P. Superantigens and their potential role in human disease. Advances in Immunology. 54: 99-166. PMID 8397479 DOI: 10.1016/S0065-2776(08)60534-9  0.304
1993 Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II Journal of Experimental Medicine. 178: 2173-2183. PMID 8245790 DOI: 10.1084/Jem.178.6.2173  0.328
1993 Hugo P, Kappler JW, Godfrey DI, Marrack PC. A cell line that can induce thymocyte positive selection. Nature. 360: 679-82. PMID 1465132 DOI: 10.1038/360679a0  0.376
1992 Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. The Journal of Experimental Medicine. 175: 387-96. PMID 1370682 DOI: 10.1084/Jem.175.2.387  0.453
1992 Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a) Cell. 71: 719-730. PMID 1330323 DOI: 10.1016/0092-8674(92)90549-R  0.346
1991 Marrack P, Kushnir E, Kappler J. A maternally inherited superantigen encoded by a mammary tumour virus. Nature. 349: 524-6. PMID 1846947 DOI: 10.1038/349524A0  0.347
1991 Herman A, Kappler JW, Marrack P, Pullen AM. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annual Review of Immunology. 9: 745-72. PMID 1832875 DOI: 10.1146/Annurev.Iy.09.040191.003525  0.433
1990 Burgert HG, White J, Weltzien HU, Marrack P, Kappler JW. Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner. The Journal of Experimental Medicine. 170: 1887-904. PMID 2511267 DOI: 10.1084/Jem.170.6.1887  0.347
1990 Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 346: 471-3. PMID 2377208 DOI: 10.1038/346471A0  0.347
1990 Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science (New York, N.Y.). 248: 705-11. PMID 2185544 DOI: 10.1126/Science.2185544  0.378
1990 Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells Journal of Experimental Medicine. 172: 709-717. PMID 2117633 DOI: 10.1084/Jem.172.3.709  0.363
1990 Pullen AM, Wade T, Marrack P, Kappler JW. Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell. 61: 1365-74. PMID 1694725 DOI: 10.1016/0092-8674(90)90700-O  0.381
1989 Marrack P, McCormack J, Kappler J. Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium. Nature. 338: 503-5. PMID 2784543 DOI: 10.1038/338503A0  0.434
1989 Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 58: 1047-54. PMID 2673539 DOI: 10.1016/0092-8674(89)90503-5  0.353
1989 Kappler J, Kotzin B, Herron L, Gelfand EW, Bigler RD, Boylston A, Carrel S, Posnett DN, Choi Y, Marrack P. Vβ-specific stimulation of human T cells by staphylococcal toxins Science. 244: 811-813. PMID 2524876 DOI: 10.1126/Science.2524876  0.427
1989 Pullen AM, Kappler JW, Marrack P. Tolerance to self antigens shapes the T-cell repertoire. Immunological Reviews. 107: 125-39. PMID 2522084 DOI: 10.1111/J.1600-065X.1989.Tb00006.X  0.348
1989 Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8941-5. PMID 2479030 DOI: 10.1073/Pnas.86.22.8941  0.35
1988 Born W, Miles C, White J, O'Brien R, Freed JH, Marrack P, Kappler J, Kubo RT. Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins. Nature. 330: 572-4. PMID 3500416 DOI: 10.1038/330572A0  0.401
1988 Pullen AM, Marrack P, Kappler JW. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature. 335: 796-801. PMID 3263572 DOI: 10.1038/335796A0  0.342
1988 Marrack P, Kappler J. T cells can distinguish between allogeneic major histocompatibility complex products on different cell types. Nature. 332: 840-3. PMID 3258650 DOI: 10.1038/332840A0  0.477
1988 Kappler JW, Staerz U, White J, Marrack PC. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature. 332: 35-40. PMID 3126396 DOI: 10.1038/332035a0  0.415
1987 Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking Nature. 330: 179-181. PMID 3499573 DOI: 10.1038/330179A0  0.4
1987 Kappler JW, Wade T, White J, Kushnir E, Blackman M, Bill J, Roehm N, Marrack P. A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell. 49: 263-71. PMID 3471350 DOI: 10.1016/0092-8674(87)90567-8  0.371
1987 Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 328: 626-9. PMID 3112582 DOI: 10.1038/328626A0  0.383
1985 Sim GK, Yagüe J, Nelson J, Marrack P, Palmer E, Augustin A, Kappler J. Primary structure of human T-cell receptor alpha-chain. Nature. 312: 771-5. PMID 6440030 DOI: 10.1038/312771A0  0.324
1985 Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunological Reviews. 81: 161-76. PMID 6392066 DOI: 10.1111/J.1600-065X.1984.Tb01109.X  0.354
1985 Golde WT, Kappler JW, Greenstein J, Malissen B, Hood L, Marrack P. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. The Journal of Experimental Medicine. 161: 635-40. PMID 3919144 DOI: 10.1084/Jem.161.3.635  0.475
1984 Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, Cambier JC. Interleukin-induced increase in Ia expression by normal mouse B cells. The Journal of Experimental Medicine. 160: 679-94. PMID 6432933 DOI: 10.1084/Jem.160.3.679  0.367
1984 Hannum CH, Kappler JW, Trowbridge IS, Marrack P, Freed JH. Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor. Nature. 312: 65-7. PMID 6333642 DOI: 10.1038/312065A0  0.356
1984 Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype Journal of Experimental Medicine. 160: 452-471. PMID 6206178 DOI: 10.1084/Jem.160.2.452  0.426
1983 Sunshine GH, Gold DP, Wortis HH, Marrack P, Kappler JW. Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas Journal of Experimental Medicine. 158: 1745-1750. PMID 6605410 DOI: 10.1084/Jem.158.5.1745  0.406
1983 Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas Cell. 34: 727-737. PMID 6605198 DOI: 10.1016/0092-8674(83)90529-9  0.405
1983 Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody Journal of Experimental Medicine. 157: 1149-1169. PMID 6601175 DOI: 10.1084/Jem.157.4.1149  0.454
1983 Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. The Journal of Experimental Medicine. 157: 600-12. PMID 6600488 DOI: 10.1084/Jem.157.2.600  0.365
1983 Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunological Reviews. 76: 131-45. PMID 6363275 DOI: 10.1111/J.1600-065X.1983.Tb01100.X  0.437
1982 Kappler J, White J, Wegmann D, Mustain E, Marrack P. Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas. Proceedings of the National Academy of Sciences of the United States of America. 79: 3604-7. PMID 6980413 DOI: 10.1073/Pnas.79.11.3604  0.408
1982 Zlotnik A, Roberts W, Blumenthal E, Marrack P, Kappler J. T-cell hybridomas as sources of lymphokines Cellular Immunology. 70: 403. DOI: 10.1016/0008-8749(82)90409-9  0.367
1978 Horan PK, Kappler JW. Automated fluorescent analysis for cytotoxicity assays. Journal of Immunological Methods. 18: 309-16. PMID 73561 DOI: 10.1016/0022-1759(77)90184-3  0.327
1977 Marrack P, Kappler JW. Anti-Ia inhibits the activity of B cells but not a T cell-derived helper mediator Immunogenetics. 4: 541-555. DOI: 10.1007/Bf01575688  0.391
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