Thomas G. Beach, MD PhD - Publications

Affiliations: 
Civin Laboratory of Neuropathology Sun Health Research Institute, Sun City, AZ, United States 
Area:
Alzheimer disease
Website:
http://www.bannerhealth.com/Innovations/Sun+Health+Research+Institute/Research+Programs/Neuropathology.htm

277 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, ... ... Beach TG, et al. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models. Nature Neuroscience. PMID 38539014 DOI: 10.1038/s41593-024-01610-w  0.311
2024 Haney MS, Pálovics R, Munson CN, Long C, Johansson PK, Yip O, Dong W, Rawat E, West E, Schlachetzki JCM, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, ... ... Beach TG, et al. APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia. Nature. PMID 38480892 DOI: 10.1038/s41586-024-07185-7  0.348
2024 Wang H, Chang TS, Dombroski BA, Cheng PL, Si YQ, Tucci A, Patil V, Valiente-Banuet L, Farrell K, Mclean C, Molina-Porcel L, Alex R, Paul De Deyn P, Le Bastard N, Gearing M, ... ... Beach TG, et al. Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and Sub-haplotypes. Medrxiv : the Preprint Server For Health Sciences. PMID 38464214 DOI: 10.1101/2024.02.26.24303379  0.413
2024 Adler CH, Serrano GE, Shill HA, Driver-Dunckley E, Mehta SH, Zhang N, Glass M, Sue LI, Intorcia A, Beach TG. Symmetry of synuclein density in autopsied Parkinson's disease submandibular glands. Neuroscience Letters. 825: 137702. PMID 38395191 DOI: 10.1016/j.neulet.2024.137702  0.552
2024 Wennström M, Schultz N, Gallardo PM, Serrano GE, Beach TG, Bose S, Hansson O. The Relationship between p-tau217, p-tau231, and p-tau205 in the Human Brain Is Affected by the Cellular Environment and Alzheimer's Disease Pathology. Cells. 13. PMID 38391945 DOI: 10.3390/cells13040331  0.544
2024 Omidsalar AA, McCullough CG, Xu L, Boedijono S, Gerke D, Webb MG, Manojlovic Z, Sequeira A, Lew MF, Santorelli M, Serrano GE, Beach TG, Limon A, Vawter MP, Hjelm BE. Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets. Communications Biology. 7: 200. PMID 38368460 DOI: 10.1038/s42003-024-05877-4  0.464
2024 Reho P, Saez-Atienzar S, Ruffo P, Solaiman S, Shah Z, Chia R, Kaivola K, Traynor BJ, Tilley BS, Gentleman SM, Hodges AK, Aarsland D, Monuki ES, Newell KL, Woltjer R, ... ... Beach TG, et al. Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies. Communications Biology. 7: 35. PMID 38182665 DOI: 10.1038/s42003-023-05725-x  0.507
2023 Wang H, Chang TS, Dombroski BA, Cheng PL, Patil V, Valiente-Banuet L, Farrell K, Mclean C, Molina-Porcel L, Rajput A, Paul De Deyn P, Le Bastard N, Gearing M, Donker Kaat L, Van Swieten JC, ... ... Beach TG, et al. Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy. Medrxiv : the Preprint Server For Health Sciences. PMID 38234807 DOI: 10.1101/2023.12.28.23300612  0.553
2023 Singh V, Menard MA, Serrano GE, Beach TG, Zhao HT, Riley-DiPaolo A, Subrahmanian N, LaVoie MJ, Volpicelli-Daley LA. Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain. Acta Neuropathologica Communications. 11: 201. PMID 38110990 DOI: 10.1186/s40478-023-01704-9  0.536
2023 Mastenbroek SE, Vogel JW, Collij LE, Serrano GE, Tremblay C, Young AL, Arce RA, Shill HA, Driver-Dunckley ED, Mehta SH, Belden CM, Atri A, Choudhury P, Barkhof F, Adler CH, ... ... Beach TG, et al. Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Biorxiv : the Preprint Server For Biology. PMID 38106128 DOI: 10.1101/2023.12.05.569878  0.587
2023 Wang Q, Antone J, Alsop E, Reiman R, Funk C, Bendl J, Dudley JT, Liang WS, Karr TL, Roussos P, Bennett DA, De Jager PL, Serrano GE, Beach TG, Keuren-Jensen KV, et al. A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease. Biorxiv : the Preprint Server For Biology. PMID 37961404 DOI: 10.1101/2023.10.20.563319  0.578
2023 Beach TG, Adler CH, Shill HA, Serrano GE, Zhang N. α-synuclein seed amplification in Parkinson's disease. The Lancet. Neurology. 22: 985. PMID 37863604 DOI: 10.1016/S1474-4422(23)00373-3  0.524
2023 Walker JE, Oliver JC, Stewart AM, Beh ST, Arce RA, Glass MJ, Vargas DE, Qiji SH, Intorcia AJ, Borja CI, Cline MP, Hemmingsen SJ, Krupp AN, McHattie RD, Mariner MR, ... ... Beach TG, et al. Measuring Up: A Comparison of TapeStation 4200 and Bioanalyzer 2100 as Measurement Tools for RNA Quality in Postmortem Human Brain Samples. International Journal of Molecular Sciences. 24. PMID 37762097 DOI: 10.3390/ijms241813795  0.444
2023 Dong X, Bai Y, Liao Z, Gritsch D, Liu X, Wang T, Borges-Monroy R, Ehrlich A, Serrano GE, Feany MB, Beach TG, Scherzer CR. Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease. Nature Communications. 14: 5327. PMID 37723137 DOI: 10.1038/s41467-023-40348-0  0.521
2023 Coomans EM, van Westen D, Pichet Binette A, Strandberg O, Spotorno N, Serrano GE, Beach TG, Palmqvist S, Stomrud E, Ossenkoppele R, Hansson O. Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation. Brain : a Journal of Neurology. PMID 37721482 DOI: 10.1093/brain/awad317  0.57
2023 Blusztajn JK, Aytan N, Rajendiran T, Mellott TJ, Soni T, Burant CF, Serrano GE, Beach TG, Lin H, Stein TD. Cerebral Gray and White Matter Monogalactosyl Diglyceride Levels Rise with the Progression of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 37718815 DOI: 10.3233/JAD-230543  0.599
2023 Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Kc A, Li W, Huang H, Lim SA, Hu H, Wang Y, Liu D, ... ... Beach TG, et al. CXCR6 orchestrates brain CD8 T cell residency and limits mouse Alzheimer's disease pathology. Nature Immunology. PMID 37679549 DOI: 10.1038/s41590-023-01604-z  0.524
2023 Sepulveda-Falla D, Villegas Lanau CA, White C, Serrano GE, Acosta-Uribe J, Mejía-Cupajita B, Villalba-Moreno ND, Lu P, Glatzel M, Kofler JK, Ghetti B, Frosch MP, Lopera Restrepo F, Kosik KS, Beach TG. Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes. Medrxiv : the Preprint Server For Health Sciences. PMID 37646002 DOI: 10.1101/2023.08.14.23294081  0.59
2023 Beach TG, Adler CH, Shill HA, Zhang N, Driver-Dunckley ED, Mehta SH, Serrano GE. Accuracy of the Early Diagnosis of Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. 38: 1573-1574. PMID 37565398 DOI: 10.1002/mds.29556  0.542
2023 Judd JM, Jasbi P, Winslow W, Serrano GE, Beach TG, Klein-Seetharaman J, Velazquez R. Inflammation and the pathological progression of Alzheimer's disease are associated with low circulating choline levels. Acta Neuropathologica. PMID 37548694 DOI: 10.1007/s00401-023-02616-7  0.572
2023 Haney MS, Pálovics R, Munson CN, Long C, Johansson P, Yip O, Dong W, Rawat E, West E, Schlachetzki JC, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, ... ... Beach TG, et al. APOE4/4 is linked to damaging lipid droplets in Alzheimer's microglia. Biorxiv : the Preprint Server For Biology. PMID 37546938 DOI: 10.1101/2023.07.21.549930  0.567
2023 Walker JE, Oliver JC, Stewart AM, Beh ST, Arce RA, Glass MJ, Vargas DE, Qiji SH, Intorcia AJ, Borja CI, Cline MP, Hemmingsen SJ, Krupp AN, McHattie RD, Mariner MR, ... ... Beach TG, et al. Measuring up: A Comparison of Tapestation 4200 and Bioanalyzer 2100 as Measurement Tools for RNA Quality in Postmortem Human Brain Samples. Medrxiv : the Preprint Server For Health Sciences. PMID 37461632 DOI: 10.1101/2023.07.03.23291969  0.444
2023 Choudhury P, Zhang N, Adler CH, Chen K, Belden C, Driver-Dunckley E, Mehta SH, Shprecher DR, Serrano GE, Shill HA, Beach TG, Atri A. Longitudinal motor decline in dementia with Lewy bodies, Parkinson disease dementia, and Alzheimer's dementia in a community autopsy cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37422286 DOI: 10.1002/alz.13357  0.6
2023 Mrdjen D, Amouzgar M, Cannon B, Liu C, Spence A, McCaffrey E, Bharadwaj A, Tebaykin D, Bukhari S, Hartmann F, Kagel A, Vijayaragavan K, Oliveria JP, Yakabi K, Serrano G, ... ... Beach T, et al. Spatial proteomics reveals human microglial states shaped by anatomy and neuropathology. Research Square. PMID 37398389 DOI: 10.21203/rs.3.rs-2987263/v1  0.523
2023 Kaivola K, Chia R, Ding J, Rasheed M, Fujita M, Menon V, Walton RL, Collins RL, Billingsley K, Brand H, Talkowski M, Zhao X, Dewan R, Stark A, Ray A, ... ... Beach TG, et al. Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias. Cell Genomics. 3: 100316. PMID 37388914 DOI: 10.1016/j.xgen.2023.100316  0.51
2023 Zaman M, Fu Y, Chen PC, Sun H, Yang S, Wu Z, Wang Z, Poudel S, Serrano GE, Beach TG, Li L, Wang X, Peng J. Dissecting detergent-insoluble proteome in Alzheimer's disease by TMTc-corrected quantitative mass spectrometry. Molecular & Cellular Proteomics : McP. 100608. PMID 37356496 DOI: 10.1016/j.mcpro.2023.100608  0.529
2023 Makarious MB, Lake J, Pitz V, Fu AY, Guidubaldi JL, Solsberg CW, Bandres-Ciga S, Leonard HL, Kim JJ, Billingsley KJ, Grenn FP, Alvarez Jerez P, Alvarado C, Iwaki H, Ta M, ... ... Beach TG, et al. Large-scale rare variant burden testing in Parkinson's disease. Brain : a Journal of Neurology. PMID 37348876 DOI: 10.1093/brain/awad214  0.528
2023 Hamsafar Y, Chen Q, Borowsky AD, Beach TG, Serrano GE, Sue LI, Adler CH, Walker DG, Dugger BN. Biochemical analyses of tau and other neuronal markers in the submandibular gland and frontal cortex across stages of Alzheimer's disease. Neuroscience Letters. 137330. PMID 37330193 DOI: 10.1016/j.neulet.2023.137330  0.587
2023 Tremblay C, Choudhury P, Belden CM, Goldfarb D, Lorenzini I, Beach TG, Serrano GE. The role of sex differences in depression in pathologically defined Alzheimer's disease. Frontiers in Aging Neuroscience. 15: 1156764. PMID 37234269 DOI: 10.3389/fnagi.2023.1156764  0.553
2023 Judd JM, Jasbi P, Winslow W, Serrano GE, Beach TG, Klein-Seetharaman J, Velazquez R. Low circulating choline, a modifiable dietary factor, is associated with the pathological progression and metabolome dysfunction in Alzheimer's disease. Biorxiv : the Preprint Server For Biology. PMID 37214864 DOI: 10.1101/2023.05.06.539713  0.557
2023 Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, ... ... Beach TG, et al. Creating the Pick's disease International Consortium: Association study of H2 haplotype with risk of Pick's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37163045 DOI: 10.1101/2023.04.17.23288471  0.565
2023 Beach TG, Sue LI, Scott S, Intorcia AJ, Walker JE, Arce RA, Glass MJ, Borja CI, Cline MP, Hemmingsen SJ, Qiji S, Stewart A, Martinez KN, Krupp A, McHattie R, et al. Cerebral white matter rarefaction has both neurodegenerative and vascular causes and may primarily be a distal axonopathy. Journal of Neuropathology and Experimental Neurology. PMID 37071794 DOI: 10.1093/jnen/nlad026  0.598
2023 Driver-Dunckley ED, Zhang N, Serrano GE, Dunckley NA, Sue LI, Shill HA, Mehta SH, Belden C, Tremblay C, Atri A, Adler CH, Beach TG. Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. PMID 37040756 DOI: 10.1093/jnen/nlad025  0.479
2023 Chahine LM, Beach TG, Adler CH, Hepker M, Kanthasamy A, Appel S, Pritzkow S, Pinho M, Mosovsky S, Serrano GE, Coffey C, Brumm MC, Oliveira LMA, Eberling J, Mollenhauer B. Central and peripheral α-synuclein in Parkinson disease detected by seed amplification assay. Annals of Clinical and Translational Neurology. PMID 36972727 DOI: 10.1002/acn3.51753  0.489
2023 Tremblay C, Serrano GE, Dunckley N, Zhang N, Fiock KL, Adler CH, Driver-Dunckley E, Mehta SH, Shill HA, Beach TG. Postmortem Cerebellar Volume Is Not Reduced in Essential Tremor: A Comparison with Multiple System Atrophy and Controls. Journal of Parkinson's Disease. PMID 36938740 DOI: 10.3233/JPD-225033  0.426
2023 Salvadó G, Ossenkoppele R, Ashton NJ, Beach TG, Serrano GE, Reiman EM, Zetterberg H, Mattsson-Carlgren N, Janelidze S, Blennow K, Hansson O. Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads. Embo Molecular Medicine. e2463. PMID 36912178 DOI: 10.15252/emmm.202217123  0.536
2023 Billingsley KJ, Ding J, Alvarez Jerez P, Illarionova A, Levine K, Grenn FP, Makarious MB, Moore A, Vitale D, Reed X, Hernandez D, Torkamani A, Ryten M, Hardy J, Chia R, ... ... Beach TG, et al. Genome-wide analysis of Structural Variants in Parkinson's Disease. Annals of Neurology. PMID 36695634 DOI: 10.1002/ana.26608  0.498
2023 Piras IS, Brokaw D, Kong Y, Weisenberger DJ, Krate J, Delvaux E, Mahurkar S, Blattler A, Siegmund KD, Sue L, Serrano GE, Beach TG, Laird PW, Huentelman MJ, Coleman PD. Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer's Disease. Cellular and Molecular Neurobiology. PMID 36596913 DOI: 10.1007/s10571-022-01307-3  0.527
2023 Hasan S, Adler CH, Zhang N, Serrano GE, Sue LI, Shill HA, Mehta SH, Beach TG, Driver-Dunckley ED. Olfactory Dysfunction in Incidental Lewy Body Disease and Parkinson's Disease: An Update. Innovations in Clinical Neuroscience. 19: 19-23. PMID 36591548  0.567
2022 Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, ... ... Beach TG, et al. Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nature Aging. 2: 923-940. PMID 36636325 DOI: 10.1038/s43587-022-00290-0  0.531
2022 Chen S, Chang Y, Li L, Acosta D, Li Y, Guo Q, Wang C, Turkes E, Morrison C, Julian D, Hester ME, Scharre DW, Santiskulvong C, Song SX, Plummer JT, ... ... Beach TG, et al. Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease. Acta Neuropathologica Communications. 10: 188. PMID 36544231 DOI: 10.1186/s40478-022-01494-6  0.571
2022 Mohebpour I, Malek-Ahmadi M, Virden T, Breitmeyer A, Sabbagh MN, Auman B, Belden CM, Choudhury P, Arch A, Davis K, Cline C, Moorley N, Atri A, Serrano G, Beach TG. Neuropathologic validation of the Alzheimer's Questionnaire. Aging Clinical and Experimental Research. PMID 36031683 DOI: 10.1007/s40520-022-02222-9  0.528
2022 Billingsley KJ, Alvarez Jerez P, Grenn FP, Bandres-Ciga S, Malik L, Hernandez D, Torkamani A, Ryten M, Hardy J, Scholz SW, Traynor BJ, Dalgard CL, Ehrlich DJ, Tanaka T, Ferrucci L, ... Beach TG, et al. Profiling the NOTCH2NLC GGC Repeat Expansion in Parkinson's Disease in the European Population. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35866887 DOI: 10.1002/mds.29155  0.515
2022 Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, Villegas A, Beach TG, White CL, Ellisman M, et al. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia. Acta Neuropathologica. PMID 35838824 DOI: 10.1007/s00401-022-02467-8  0.325
2022 Serrano GE, Walker JE, Tremblay C, Piras IS, Huentelman MJ, Belden CM, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Caselli R, Woodruff BK, ... ... Beach TG, et al. SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19. Journal of Neuropathology and Experimental Neurology. PMID 35818336 DOI: 10.1093/jnen/nlac056  0.473
2022 Tremblay C, Serrano GE, Intorcia AJ, Mariner MR, Sue LI, Arce RA, Atri A, Adler CH, Belden CM, Shill HA, Driver-Dunckley E, Mehta SH, Beach TG. Olfactory Bulb Amyloid-β Correlates With Brain Thal Amyloid Phase and Severity of Cognitive Impairment. Journal of Neuropathology and Experimental Neurology. PMID 35751438 DOI: 10.1093/jnen/nlac042  0.582
2022 Hall S, Orrù CD, Serrano GE, Galasko D, Hughson AG, Groveman BR, Adler CH, Beach TG, Caughey B, Hansson O. Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease. Acta Neuropathologica Communications. 10: 90. PMID 35733234 DOI: 10.1186/s40478-022-01388-7  0.558
2022 Beach TG. A History of Senile Plaques: From Alzheimer to Amyloid Imaging. Journal of Neuropathology and Experimental Neurology. 81: 387-413. PMID 35595841 DOI: 10.1093/jnen/nlac030  0.314
2022 Helboe L, Rosenqvist N, Volbracht C, Pedersen LØ, Pedersen JT, Christensen S, Egebjerg J, Christoffersen CT, Bang-Andersen B, Beach TG, Serrano GE, Falsig J. Highly Specific and Sensitive Target Binding by the Humanized pS396-Tau Antibody hC10.2 Across a Wide Spectrum of Alzheimer's Disease and Primary Tauopathy Postmortem Brains. Journal of Alzheimer's Disease : Jad. PMID 35570492 DOI: 10.3233/JAD-220125  0.601
2022 Tremblay C, Serrano GE, Intorcia AJ, Sue LI, Wilson JR, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Beach TG. Effect of olfactory bulb pathology on olfactory function in normal aging. Brain Pathology (Zurich, Switzerland). e13075. PMID 35485279 DOI: 10.1111/bpa.13075  0.526
2022 Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, ... ... Beach TG, et al. Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathologica. PMID 35389045 DOI: 10.1007/s00401-022-02417-4  0.564
2022 Alsop E, Meechoovet B, Kitchen R, Sweeney T, Beach TG, Serrano GE, Hutchins E, Ghiran I, Reiman R, Syring M, Hsieh M, Courtright-Lim A, Valkov N, Whitsett TG, Rakela J, et al. A Novel Tissue Atlas and Online Tool for the Interrogation of Small RNA Expression in Human Tissues and Biofluids. Frontiers in Cell and Developmental Biology. 10: 804164. PMID 35317387 DOI: 10.3389/fcell.2022.804164  0.45
2022 Tremblay C, Serrano GE, Intorcia AJ, Curry J, Sue LI, Nelson CM, Walker JE, Glass MJ, Arce RA, Fleisher AS, Pontecorvo MJ, Atri A, Montine TJ, Chen K, Beach TG. Hemispheric Asymmetry and Atypical Lobar Progression of Alzheimer-Type Tauopathy. Journal of Neuropathology and Experimental Neurology. 81: 158-171. PMID 35191506 DOI: 10.1093/jnen/nlac008  0.554
2022 Signaevsky M, Marami B, Prastawa M, Tabish N, Iida MA, Zhang XF, Sawyer M, Duran I, Koenigsberg DG, Bryce CH, Chahine LM, Mollenhauer B, Mosovsky S, Riley L, Dave KD, ... ... Beach TG, et al. Antemortem detection of Parkinson's disease pathology in peripheral biopsies using artificial intelligence. Acta Neuropathologica Communications. 10: 21. PMID 35164870 DOI: 10.1186/s40478-022-01318-7  0.513
2022 Röltgen K, Nielsen SCA, Silva O, Younes SF, Zaslavsky M, Costales C, Yang F, Wirz OF, Solis D, Hoh RA, Wang A, Arunachalam PS, Colburg D, Zhao S, Haraguchi E, ... ... Beach TG, et al. Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination. Cell. PMID 35148837 DOI: 10.1016/j.cell.2022.01.018  0.386
2022 Lea R, Benge JF, Adler CH, Beach TG, Belden CM, Zhang N, Shill HA, Driver-Dunckley E, Mehta SH, Atri A. An initial exploration of the convergent and ecological validity of the UDS 3.0 neuropsychological battery in Parkinson's Disease. Journal of Clinical and Experimental Neuropsychology. 1-8. PMID 35138228 DOI: 10.1080/13803395.2022.2034753  0.335
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.584
2022 Wennström M, Janelidze S, Nilsson KPR, Serrano GE, Beach TG, Dage JL, Hansson O. Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levels. Acta Neuropathologica Communications. 10: 3. PMID 34991721 DOI: 10.1186/s40478-021-01307-2  0.545
2021 Tiklová K, Gillberg L, Volakakis N, Lundén-Miguel H, Dahl L, Serrano GE, Adler CH, Beach TG, Perlmann T. Disease Duration Influences Gene Expression in Neuromelanin-Positive Cells From Parkinson's Disease Patients. Frontiers in Molecular Neuroscience. 14: 763777. PMID 34867188 DOI: 10.3389/fnmol.2021.763777  0.544
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Beach TG, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.345
2021 Hay M, Ryan L, Huentelman M, Konhilas J, Hoyer-Kimura C, Beach TG, Serrano GE, Reiman EM, Blennow K, Zetterberg H, Parthasarathy S. Serum Neurofilament Light is elevated in COVID-19 Positive Adults in the ICU and is associated with Co-Morbid Cardiovascular Disease, Neurological Complications, and Acuity of Illness. Cardiology and Cardiovascular Medicine. 5: 551-565. PMID 34708189 DOI: 10.26502/fccm.92920221  0.481
2021 Piras IS, Huentelman MJ, Walker JE, Arce R, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Suszczewicz KE, Borja CL, Desforges M, Deture M, Dickson DW, Beach TG, et al. Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 34545375 DOI: 10.1101/2021.09.12.21263291  0.44
2021 Adler CH, Beach TG, Zhang N, Shill HA, Driver-Dunckley E, Mehta SH, Atri A, Caviness JN, Serrano G, Shprecher DR, Sue LI, Belden CM. Clinical Diagnostic Accuracy of Early/Advanced Parkinson Disease: An Updated Clinicopathologic Study. Neurology. Clinical Practice. 11: e414-e421. PMID 34484939 DOI: 10.1212/CPJ.0000000000001016  0.532
2021 Arias JC, Edwards M, Vitali F, Beach TG, Serrano GE, Weinkauf CC. Extracranial carotid atherosclerosis is associated with increased neurofibrillary tangle accumulation. Journal of Vascular Surgery. PMID 34478810 DOI: 10.1016/j.jvs.2021.07.238  0.596
2021 Mendsaikhan A, Tooyama I, Serrano GE, Beach TG, Walker DG. Loss of Lysosomal Proteins Progranulin and Prosaposin Associated with Increased Neurofibrillary Tangle Development in Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 34374777 DOI: 10.1093/jnen/nlab056  0.602
2021 Jasbi P, Shi X, Chu P, Elliott N, Hudson H, Jones D, Serrano G, Chow B, Beach TG, Liu L, Jentarra G, Gu H. Metabolic Profiling of Neocortical Tissue Discriminates Alzheimer's Disease from Mild Cognitive Impairment, High Pathology Controls, and Normal Controls. Journal of Proteome Research. PMID 34355917 DOI: 10.1021/acs.jproteome.1c00290  0.565
2021 Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, et al. Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study. Acta Neuropathologica Communications. 9: 134. PMID 34353357 DOI: 10.1186/s40478-021-01233-3  0.316
2021 Chen X, Sun G, Tian E, Zhang M, Davtyan H, Beach TG, Reiman EM, Blurton-Jones M, Holtzman DM, Shi Y. Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101462. PMID 34337898 DOI: 10.1002/advs.202101462  0.333
2021 Hartlage-Rübsamen M, Bluhm A, Moceri S, Machner L, Köppen J, Schenk M, Hilbrich I, Holzer M, Weidenfeller M, Richter F, Coras R, Serrano GE, Beach TG, Schilling S, von Hörsten S, et al. A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies. Acta Neuropathologica. PMID 34309760 DOI: 10.1007/s00401-021-02349-5  0.517
2021 Beach TG, Adler CH, Sue LI, Shill HA, Driver-Dunckley E, Mehta SH, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Serrano GE. Vagus Nerve and Stomach Synucleinopathy in Parkinson's Disease, Incidental Lewy Body Disease, and Normal Elderly Subjects: Evidence Against the "Body-First" Hypothesis. Journal of Parkinson's Disease. PMID 34151862 DOI: 10.3233/JPD-212733  0.539
2021 Gu J, Barrera J, Yun Y, Murphy SK, Beach TG, Woltjer RL, Serrano GE, Kantor B, Chiba-Falek O. Cell-Type Specific Changes in DNA Methylation of Intron 1 in Synucleinopathy Brains. Frontiers in Neuroscience. 15: 652226. PMID 33994928 DOI: 10.3389/fnins.2021.652226  0.514
2021 Dave N, Vural AS, Piras IS, Winslow W, Surendra L, Winstone JK, Beach TG, Huentelman MJ, Velazquez R. Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer's disease and related tauopathies. Acta Neuropathologica. PMID 33978814 DOI: 10.1007/s00401-021-02323-1  0.317
2021 Mattsson-Carlgren N, Janelidze S, Bateman RJ, Smith R, Stomrud E, Serrano GE, Reiman EM, Palmqvist S, Dage JL, Beach TG, Hansson O. Soluble P-tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau. Embo Molecular Medicine. e14022. PMID 33949133 DOI: 10.15252/emmm.202114022  0.563
2021 Beach TG, Sue LI, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Serrano GE. Acute Brain Ischemia, Infarction and Hemorrhage in Subjects Dying with or Without Autopsy-Proven Acute Pneumonia. Medrxiv : the Preprint Server For Health Sciences. PMID 33791728 DOI: 10.1101/2021.03.22.21254139  0.435
2021 Shill HA, Zhang N, Driver-Dunckley E, Mehta S, Adler CH, Beach TG. Olfaction in Neuropathologically Defined Progressive Supranuclear Palsy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33755262 DOI: 10.1002/mds.28568  0.355
2021 Gupta HV, Beach TG, Mehta SH, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Liebsack C, Dugger BN, Serrano GE, Sue LI, Siderowf A, Pontecorvo MJ, Mintun MA, Joshi AD, et al. Clinicopathological Correlation: Dopamine and Amyloid PET Imaging with Neuropathology in Three Subjects Clinically Diagnosed with Alzheimer's Disease or Dementia with Lewy Bodies. Journal of Alzheimer's Disease : Jad. PMID 33720879 DOI: 10.3233/JAD-200323  0.577
2021 Serrano GE, Walker JE, Arce R, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Papa J, Russell A, Suszczewicz KE, Borja CI, Belden C, Goldfarb D, ... ... Beach TG, et al. Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 33619496 DOI: 10.1101/2021.02.15.21251511  0.515
2021 Nichols JB, Malek-Ahmadi M, Tariot PN, Serrano GE, Sue LI, Beach TG. Vascular Lesions, APOE ε4, and Tau Pathology in Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. 80: 240-246. PMID 33617650 DOI: 10.1093/jnen/nlaa160  0.564
2021 Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, ... ... Beach TG, et al. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. PMID 33589841 DOI: 10.1038/s41588-021-00785-3  0.514
2021 Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, et al. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature Genetics. PMID 33510477 DOI: 10.1038/s41588-020-00773-z  0.33
2021 Beach TG, Russell A, Sue LI, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Hidalgo T, Chiarolanza G, Mariner M, Scroggins A, Pullen J, Souders L, Sivananthan K, et al. Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 33442709 DOI: 10.1101/2021.01.07.21249410  0.573
2021 Beach TG, Malek-Ahmadi M. Alzheimer's Disease Neuropathological Comorbidities are Common in the Younger-Old. Journal of Alzheimer's Disease : Jad. 79: 389-400. PMID 33285640 DOI: 10.3233/JAD-201213  0.363
2020 Liu D, Yang S, Kavdia K, Sifford JM, Wu Z, Xie B, Wang Z, Pagala VR, Wang H, Yu K, Dey KK, High AA, Serrano GE, Beach TG, Peng J. Deep Profiling of Microgram-Scale Proteome by Tandem Mass Tag Mass Spectrometry. Journal of Proteome Research. PMID 33175545 DOI: 10.1021/acs.jproteome.0c00426  0.469
2020 Beh ST, Frisch C, Brafman DA, Churko J, Walker JE, Serrano GE, Sue LI, Reiman EM, Beach TG, Lue LF. Human Autopsy-Derived Scalp Fibroblast Biobanking for Age-Related Neurodegenerative Disease Research. Cells. 9. PMID 33143239 DOI: 10.3390/cells9112383  0.535
2020 Manne S, Kondru N, Jin H, Serrano GE, Anantharam V, Kanthasamy A, Adler CH, Beach TG, Kanthasamy AG. Blinded RT-QuIC Analysis of α-Synuclein Biomarker in Skin Tissue from Parkinson's Disease Patients. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32960470 DOI: 10.1002/Mds.28242  0.533
2020 Ortuño-Lizarán I, Sánchez-Sáez X, Lax P, Serrano GE, Beach TG, Adler CH, Cuenca N. Dopaminergic retinal cell loss and visual dysfunction in Parkinson's disease. Annals of Neurology. PMID 32881029 DOI: 10.1002/ana.25897  0.502
2020 Migrino RQ, Karamanova N, Truran S, Serrano GE, Davies HA, Madine J, Beach TG. Cerebrovascular medin is associated with Alzheimer's disease and vascular dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12072. PMID 32875054 DOI: 10.1002/dad2.12072  0.593
2020 Sekar S, Geiger P, Adkins J, Tassone E, Serrano G, Beach TG, Liang WS. ACValidator: A novel assembly-based approach for verification of circular RNAs. Biology Methods & Protocols. 5: bpaa010. PMID 32793805 DOI: 10.1093/biomethods/bpaa010  0.412
2020 Chahine LM, Beach TG, Brumm MC, Adler CH, Coffey CS, Mosovsky S, Caspell-Garcia C, Serrano GE, Munoz DG, White CL, Crary JF, Jennings D, Taylor P, Foroud T, Arnedo V, et al. In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease. Neurology. PMID 32747521 DOI: 10.1212/Wnl.0000000000010404  0.515
2020 Brokaw DL, Piras IS, Mastroeni D, Weisenberger DJ, Nolz J, Delvaux E, Serrano GE, Beach TG, Huentelman MJ, Coleman PD. Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets. Neurobiology of Aging. 95: 15-25. PMID 32745806 DOI: 10.1016/J.Neurobiolaging.2020.06.022  0.513
2020 Palmqvist S, Janelidze S, Quiroz YT, Zetterberg H, Lopera F, Stomrud E, Su Y, Chen Y, Serrano GE, Leuzy A, Mattsson-Carlgren N, Strandberg O, Smith R, Villegas A, Sepulveda-Falla D, ... ... Beach TG, et al. Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders. Jama. PMID 32722745 DOI: 10.1001/Jama.2020.12134  0.584
2020 Wang H, Dey KK, Chen PC, Li Y, Niu M, Cho JH, Wang X, Bai B, Jiao Y, Chepyala SR, Haroutunian V, Zhang B, Beach TG, Peng J. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. Molecular Neurodegeneration. 15: 43. PMID 32711556 DOI: 10.1186/S13024-020-00384-6  0.305
2020 Srinivasan K, Friedman BA, Etxeberria A, Huntley MA, van der Brug MP, Foreman O, Paw JS, Modrusan Z, Beach TG, Serrano GE, Hansen DV. Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation. Cell Reports. 31: 107843. PMID 32610143 DOI: 10.1016/J.Celrep.2020.107843  0.567
2020 Pontecorvo MJ, Keene CD, Beach TG, Montine TJ, Arora AK, Devous MD, Navitsky M, Kennedy I, Joshi AD, Lu M, Serrano GE, Sue LI, Intorcia AJ, Rose SE, Wilson A, et al. Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer's disease pathology: a clinicopathological study. Ejnmmi Research. 10: 65. PMID 32542468 DOI: 10.1186/S13550-020-00653-X  0.571
2020 Piras IS, Bleul C, Schrauwen I, Talboom J, Llaci L, De Both MD, Naymik MA, Halliday G, Bettencourt C, Holton JL, Serrano GE, Sue LI, Beach TG, Stefanova N, Huentelman MJ. Transcriptional profiling of multiple system atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease. Acta Neuropathologica Communications. 8: 76. PMID 32493431 DOI: 10.1186/S40478-020-00950-5  0.542
2020 Yin J, Reiman EM, Beach TG, Serrano GE, Sabbagh MN, Nielsen M, Caselli RJ, Shi J. Effect of ApoE isoforms on mitochondria in Alzheimer disease. Neurology. PMID 32457210 DOI: 10.1212/WNL.0000000000009582  0.541
2020 Fleisher AS, Pontecorvo MJ, Devous MD, Lu M, Arora AK, Truocchio SP, Aldea P, Flitter M, Locascio T, Devine M, Siderowf A, Beach TG, Montine TJ, Serrano GE, Curtis C, et al. Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes. Jama Neurology. PMID 32338734 DOI: 10.1001/Jamaneurol.2020.0528  0.524
2020 Beach TG, Adler CH, Zhang N, Serrano GE, Sue LI, Driver-Dunckley E, Mehta SH, Zamrini EE, Sabbagh MN, Shill HA, Belden CM, Shprecher DR, Caselli RJ, Reiman EM, Davis KJ, et al. Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer's disease dementia. Plos One. 15: e0231720. PMID 32320406 DOI: 10.1371/Journal.Pone.0231720  0.589
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  0.353
2020 Schechter M, Grigoletto J, Abd-Elhadi S, Glickstein H, Friedman A, Serrano GE, Beach TG, Sharon R. A role for α-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson's disease. Molecular Neurodegeneration. 15: 24. PMID 32228705 DOI: 10.1186/s13024-020-00370-y  0.506
2020 Piras IS, Bleul C, Talboom JS, De Both MD, Schrauwen I, Halliday G, Myers AJ, Serrano GE, Beach TG, Huentelman MJ. ESHRD: deconvolution of brain homogenate RNA expression data to identify cell-type-specific alterations in Alzheimer's disease. Aging. 12. PMID 32125278 DOI: 10.18632/aging.102840  0.512
2020 Janelidze S, Mattsson N, Palmqvist S, Smith R, Beach TG, Serrano GE, Chai X, Proctor NK, Eichenlaub U, Zetterberg H, Blennow K, Reiman EM, Stomrud E, Dage JL, Hansson O. Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia. Nature Medicine. PMID 32123385 DOI: 10.1038/s41591-020-0755-1  0.587
2020 Serrano GE, Shprecher D, Callan M, Cutler B, Glass M, Zhang N, Walker J, Intorcia A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Belden CM, Zamrini E, Sue LI, ... ... Beach TG, et al. Cardiac sympathetic denervation and synucleinopathy in Alzheimer's disease with brain Lewy body disease. Brain Communications. 2: fcaa004. PMID 32064463 DOI: 10.1093/braincomms/fcaa004  0.6
2020 Knox MG, Adler CH, Shill HA, Driver-Dunckley E, Mehta SA, Belden C, Zamrini E, Serrano G, Sabbagh MN, Caviness JN, Sue LI, Davis KJ, Dugger BN, Beach TG. Neuropathological Findings in Parkinson's Disease With Mild Cognitive Impairment. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32034933 DOI: 10.1002/Mds.27991  0.581
2020 Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, et al. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nature Communications. 11: 667. PMID 32015339 DOI: 10.1038/S41467-019-14279-8  0.358
2020 Ornelas AS, Adler CH, Serrano GE, Curry JR, Shill HA, Kopyov O, Beach TG. Co-Existence of tau and α-synuclein pathology in fetal graft tissue at autopsy: A case report. Parkinsonism & Related Disorders. 71: 36-39. PMID 32004818 DOI: 10.1016/j.parkreldis.2019.12.013  0.547
2020 Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, ... ... Beach TG, et al. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications. 8: 5. PMID 31996268 DOI: 10.1186/S40478-020-0879-Z  0.58
2020 Walker DG, Tang TM, Mendsaikhan A, Tooyama I, Serrano GE, Sue LI, Beach TG, Lue LF. Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. International Journal of Molecular Sciences. 21. PMID 31968618 DOI: 10.3390/ijms21020678  0.571
2020 Shprecher DR, Serrano GE, Zhang N, Intorcia A, Davis KJ, Glass M, Curry J, Walker J, Cutler B, Callan M, Garcia A, Sue LI, Beach TG. Prevalence of REM sleep behavior disorder in Sun City, Arizona. Heliyon. 6: e03140. PMID 31938745 DOI: 10.1016/J.Heliyon.2019.E03140  0.415
2020 Karamanova N, Truran S, Serrano GE, Beach TG, Madine J, Weissig V, Davies HA, Veldhuizen J, Nikkhah M, Hansen M, Zhang W, D'Souza K, Franco DA, Migrino RQ. Endothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside-Containing Nanoliposomes. Journal of the American Heart Association. 9: e014810. PMID 31928157 DOI: 10.1161/Jaha.119.014810  0.485
2020 Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Beach TG, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. PMID 31926610 DOI: 10.1016/J.Neuron.2019.12.015  0.33
2019 Mendsaikhan A, Tooyama I, Bellier JP, Serrano GE, Sue LI, Lue LF, Beach TG, Walker DG. Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology. Acta Neuropathologica Communications. 7: 215. PMID 31864418 DOI: 10.1186/s40478-019-0862-8  0.595
2019 Sekar S, Geiger P, Cuyugan L, Boyle A, Serrano G, Beach TG, Liang WS. Identification of Circular RNAs using RNA Sequencing. Journal of Visualized Experiments : Jove. PMID 31789321 DOI: 10.3791/59981  0.427
2019 Thal DR, Ronisz A, Tousseyn T, Rijal Upadhaya A, Balakrishnan K, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Otto M, Beach TG, Lilja J, Heurling K, Chakrabarty A, Ismail A, Buckley C, et al. Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia. Acta Neuropathologica Communications. 7: 178. PMID 31727169 DOI: 10.1186/S40478-019-0837-9  0.336
2019 Adler CH, Serrano GE, Zhang N, Hinni ML, Lott DG, Mehta SH, Sue LI, Intorcia A, Beach TG. Feasibility of repeat and bilateral submandibular gland needle biopsies in Parkinson's disease. Parkinsonism & Related Disorders. 68: 69-72. PMID 31621624 DOI: 10.1016/j.parkreldis.2019.10.006  0.523
2019 Adler CH, Beach TG, Zhang N, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Belden CM, Powell J, Jacobson SA, Zamrini E, Shprecher D, et al. Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging. Journal of Neuropathology and Experimental Neurology. PMID 31504679 DOI: 10.1093/Jnen/Nlz080  0.48
2019 Lue LF, Beach TG, Walker DG. Alzheimer's Disease Research Using Human Microglia. Cells. 8. PMID 31387311 DOI: 10.3390/cells8080838  0.315
2019 Driver-Dunckley ED, Zhang N, Adler CH, Serrano GE, Sue LI, Shill HA, Mehta SH, Belden CM, Zamrini EY, Davis K, Beach TG. Brain Lewy-Type Synucleinopathy Density Is Associated with a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients with Parkinson's Disease1. Journal of Parkinson's Disease. PMID 31282425 DOI: 10.3233/JPD-191610  0.534
2019 Malek-Ahmadi M, Beach TG, Zamrini E, Adler CH, Sabbagh MN, Shill HA, Jacobson SA, Belden CM, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Caviness JN, Driver-Dunckley E, et al. Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease. Plos One. 14: e0217566. PMID 31237877 DOI: 10.1371/Journal.Pone.0217566  0.61
2019 Piras IS, Krate J, Delvaux E, Nolz J, De Both MD, Mastroeni DF, Serrano GE, Sue LI, Beach TG, Coleman PD, Huentelman MJ. Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus. Brain Research. 1719: 217-224. PMID 31176712 DOI: 10.1016/J.Brainres.2019.06.004  0.547
2019 El-Nazer R, Adler CH, Beach TG, Belden CM, Artz J, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Zamrini E, Benge JF. Regional neuropathology distribution and verbal fluency impairments in Parkinson's disease. Parkinsonism & Related Disorders. PMID 31109728 DOI: 10.1016/j.parkreldis.2019.05.014  0.55
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong DM, Troncosco JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature Communications. 10: 1619. PMID 30962425 DOI: 10.1038/S41467-019-09613-Z  0.456
2019 Li S, Yin J, Nielsen M, Beach TG, Guo L, Shi J. Sirtuin 3 Mediates Tau Deacetylation. Journal of Alzheimer's Disease : Jad. PMID 30958373 DOI: 10.3233/JAD-190014  0.342
2019 Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, ... ... Beach TG, et al. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease. PMID 30953760 DOI: 10.1016/J.Nbd.2019.04.004  0.539
2019 Christensen KR, Beach TG, Serrano GE, Kanaan NM. Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways. Acta Neuropathologica Communications. 7: 29. PMID 30819250 DOI: 10.1186/S40478-019-0675-9  0.514
2019 Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, et al. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of Disease. PMID 30798004 DOI: 10.1016/J.Nbd.2019.02.016  0.563
2018 Dugger BN, Hoffman BR, Scroggins A, Serrano GE, Adler CH, Shill HA, Belden CM, Sabbagh MN, Caviness JN, Driver Dunckley E, Beach TG. Tau immunoreactivity in peripheral tissues of human aging and select tauopathies. Neuroscience Letters. 696: 132-139. PMID 30579993 DOI: 10.1016/J.Neulet.2018.12.031  0.531
2018 Cicognola C, Brinkmalm G, Wahlgren J, Portelius E, Gobom J, Cullen NC, Hansson O, Parnetti L, Constantinescu R, Wildsmith K, Chen HH, Beach TG, Lashley T, Zetterberg H, Blennow K, et al. Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease. Acta Neuropathologica. PMID 30547227 DOI: 10.1007/s00401-018-1948-2  0.324
2018 Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, ... ... Beach TG, et al. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiology of Aging. PMID 30448004 DOI: 10.1016/J.Neurobiolaging.2018.10.019  0.532
2018 Chen HH, Liu P, Auger P, Lee SH, Adolfsson O, Rey-Bellet L, Lafrance-Vanasse J, Friedman BA, Pihlgren M, Muhs A, Pfeifer A, Ernst J, Ayalon G, Wildsmith KR, Beach TG, et al. Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression. Scientific Reports. 8: 16725. PMID 30425303 DOI: 10.1038/s41598-018-35130-y  0.379
2018 Gupta HV, Mehta SH, Zhang N, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Dugger BN, Beach TG, Serrano GE, Sue LI, Davis K, Adler CH. Are Clinical Certainty Ratings Helpful in the Diagnosis of Parkinson's Disease? Movement Disorders Clinical Practice. 5: 165-170. PMID 30363433 DOI: 10.1002/Mdc3.12589  0.51
2018 Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, et al. Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4). Journal of Parkinson's Disease. PMID 30248065 DOI: 10.3233/Jpd-181434  0.525
2018 Savica R, Beach TG, Hentz JG, Sabbagh MN, Serrano GE, Sue LI, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Jacobson SA, Belden CM, Davis KJ, Zamrini E, et al. Lewy Body P:athology in Alzheimer's Disease: A Clinicopathological Prospective Study. Acta Neurologica Scandinavica. PMID 30229861 DOI: 10.1111/Ane.13028  0.572
2018 Ortuño-Lizarán I, Esquiva G, Beach TG, Serrano GE, Adler CH, Lax P, Cuenca N. Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson's disease. Acta Neuropathologica Communications. 6: 90. PMID 30201049 DOI: 10.1186/s40478-018-0596-z  0.501
2018 Maarouf CL, Walker JE, Sue LI, Dugger BN, Beach TG, Serrano GE. Impaired hepatic amyloid-beta degradation in Alzheimer's disease. Plos One. 13: e0203659. PMID 30192871 DOI: 10.1371/Journal.Pone.0203659  0.569
2018 Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, ... ... Beach TG, et al. The human brainome: network analysis identifies HSPA2 as a novel Alzheimer's disease target. Brain : a Journal of Neurology. PMID 30137212 DOI: 10.1093/Brain/Awy215  0.576
2018 Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL, Schneider J, Crary JF, Sue LI, Adler CH, et al. Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). Journal of Neuropathology and Experimental Neurology. PMID 30107604 DOI: 10.1093/Jnen/Nly056  0.502
2018 Shprecher DR, Adler CH, Zhang N, Hentz JG, Serrano GE, Dugger BN, Shill HA, Savica R, Caviness JN, Sabbagh MN, Belden CM, Driver-Dunckley E, Mehta SH, Sue LI, Davis KJ, ... ... Beach TG, et al. Predicting alpha-synuclein pathology by REM sleep behavior disorder diagnosis. Parkinsonism & Related Disorders. PMID 29779682 DOI: 10.1016/J.Parkreldis.2018.05.020  0.443
2018 Migrino RQ, Truran S, Karamanova N, Serrano G, Madrigal C, Davies HA, Madine J, Reaven P, Beach TG. Human cerebral collateral arteriole function in normal cognition, mild cognitive impairment and dementia subjects. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29775413 DOI: 10.1152/ajpheart.00206.2018  0.539
2018 Ortuño-Lizarán I, Beach TG, Serrano GE, Walker DG, Adler CH, Cuenca N. Phosphorylated α-synuclein in the retina is a biomarker of Parkinson's disease pathology severity. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29737566 DOI: 10.1002/mds.27392  0.53
2018 Yin J, Han P, Song M, Nielsen M, Beach TG, Serrano GE, Liang WS, Caselli RJ, Shi J. Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer's Disease. Molecular Neurobiology. PMID 29574628 DOI: 10.1007/s12035-018-0977-0  0.601
2018 Pal G, Ouyang B, Verhagen L, Serrano G, Shill HA, Adler CH, Beach TG, Kordower JH. Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29380902 DOI: 10.1002/Mds.27280  0.507
2018 Beach TG, Maarouf CL, Intorcia A, Sue LI, Serrano GE, Lu M, Joshi A, Pontecorvo MJ, Roher AE. Antemortem-Postmortem Correlation of Florbetapir (18F) PET Amyloid Imaging with Quantitative Biochemical Measures of Aβ42 but not Aβ40. Journal of Alzheimer's Disease : Jad. 61: 1509-1516. PMID 29376867 DOI: 10.3233/JAD-170762  0.548
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, ... ... Beach TG, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.544
2017 Park HJ, Lee KW, Oh S, Yan R, Zhang J, Beach TG, Adler CH, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 29281045 DOI: 10.1093/Jnen/Nlx110  0.305
2017 Mastroeni D, Nolz J, Sekar S, Delvaux E, Serrano G, Cuyugan L, Liang WS, Beach TG, Rogers J, Coleman PD. Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain. Neurobiology of Aging. 63: 12-21. PMID 29207277 DOI: 10.1016/j.neurobiolaging.2017.10.019  0.59
2017 Caviness JN, Beach TG, Hentz JG, Shill HA, Driver-Dunckley ED, Adler CH. Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease. Clinical Eeg and Neuroscience. 1550059417696179. PMID 29161906 DOI: 10.1177/1550059417696179  0.385
2017 Gerkin RC, Adler CH, Hentz JG, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Caviness JN, Dugger BN, Serrano G, Belden C, Smith BH, Sue L, Davis KJ, Zamrini E, ... Beach TG, et al. Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype. Annals of Clinical and Translational Neurology. 4: 714-721. PMID 29046880 DOI: 10.1002/Acn3.447  0.531
2017 Migrino RQ, Davies HA, Truran S, Karamanova N, Franco DA, Beach TG, Serrano GE, Truong D, Nikkhah M, Madine J. Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts. Cardiovascular Research. 113: 1389-1402. PMID 28859297 DOI: 10.1093/Cvr/Cvx135  0.431
2017 Roher AE, Kokjohn TA, Clarke SG, Sierks MR, Maarouf CL, Serrano GE, Sabbagh MS, Beach TG. APP/Aβ structural diversity and Alzheimer's disease pathogenesis. Neurochemistry International. PMID 28811267 DOI: 10.1016/J.Neuint.2017.08.007  0.572
2017 Beach TG. A Review of Biomarkers for Neurodegenerative Disease: Will They Swing Us Across the Valley? Neurology and Therapy. 6: 5-13. PMID 28733961 DOI: 10.1007/s40120-017-0072-x  0.343
2017 Cabrera E, Mathews P, Mezhericher E, Beach TG, Deng J, Neubert TA, Rostagno A, Ghiso J. Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition. Biochimica Et Biophysica Acta. PMID 28711595 DOI: 10.1016/J.Bbadis.2017.07.005  0.303
2017 Dashtipour K, Tafreshi A, Adler C, Beach T, Chen X, Serrano G, Tashiro S, Wang C. Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson's Disease. Brain Sciences. 7. PMID 28653979 DOI: 10.3390/brainsci7070074  0.531
2017 Caselli RJ, Beach TG, Knopman DS, Graff-Radford NR. Alzheimer Disease: Scientific Breakthroughs and Translational Challenges. Mayo Clinic Proceedings. 92: 978-994. PMID 28578785 DOI: 10.1016/j.mayocp.2017.02.011  0.366
2017 Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings. Movement Disorders : Official Journal of the Movement Disorder Society. 32: 722-723. PMID 28513078 DOI: 10.1002/Mds.27044  0.545
2017 Hosokawa M, Kondo H, Serrano GE, Beach TG, Robinson AC, Mann DM, Akiyama H, Hasegawa M, Arai T. Accumulation of multiple neurodegenerative disease-related proteins in familial frontotemporal lobar degeneration associated with granulin mutation. Scientific Reports. 7: 1513. PMID 28473694 DOI: 10.1038/s41598-017-01587-6  0.562
2017 Tagliafierro L, Glenn OC, Zamora ME, Beach TG, Woltjer RL, Lutz MW, Chiba-Falek O. Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's compared to dementia with Lewy bodies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28431219 DOI: 10.1016/j.jalz.2017.03.001  0.32
2017 Walker DG, Lue LF, Tang TM, Adler CH, Caviness JN, Sabbagh MN, Serrano GE, Sue LI, Beach TG. Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology. Neurobiology of Aging. PMID 28390825 DOI: 10.1016/j.neurobiolaging.2017.03.007  0.609
2017 Piras IS, Krate J, Schrauwen I, Corneveaux JJ, Serrano GE, Sue L, Beach TG, Huentelman MJ. Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway. Hippocampus. PMID 28380666 DOI: 10.1002/Hipo.22731  0.476
2017 Visanji NP, Mollenhauer B, Beach TG, Adler CH, Coffey CS, Kopil CM, Dave KD, Foroud T, Chahine L, Jennings D. The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease. Biomarkers in Medicine. PMID 28353371 DOI: 10.2217/Bmm-2016-0366  0.301
2017 Tanaka Y, Suzuki G, Matsuwaki T, Hosokawa M, Serrano G, Beach TG, Yamanouchi K, Hasegawa M, Nishihara M. Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes. Human Molecular Genetics. PMID 28073925 DOI: 10.1093/hmg/ddx011  0.481
2017 Lee JM, Derkinderen P, Kordower JH, Freeman R, Munoz DG, Kremer T, Zago W, Hutten SJ, Adler CH, Serrano GE, Beach TG. The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease. Journal of Neuropathology and Experimental Neurology. PMID 28069931 DOI: 10.1093/Jnen/Nlw103  0.529
2017 Han P, Serrano G, Beach TG, Caselli RJ, Yin J, Zhuang N, Shi J. A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor. Journal of Neuropathology and Experimental Neurology. PMID 28069930 DOI: 10.1093/jnen/nlw105  0.573
2017 Dugger BN, Malek-Ahmadi M, Monsell SE, Kukull WA, Woodruff BK, Reiman EM, Beach TG, Wilson J. A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases. Alzheimer Disease and Associated Disorders. 30: 223-9. PMID 26756386 DOI: 10.1097/WAD.0000000000000138  0.361
2016 Pal GD, Ouyang B, Serrano G, Shill HA, Goetz C, Stebbins G, Metman LV, Driver-Dunckley E, Mehta SH, Caviness JN, Sabbagh MN, Adler CH, Beach TG. Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27911008 DOI: 10.1002/Mds.26882  0.538
2016 Roher AE, Maarouf CL, Kokjohn TA, Belden C, Serrano G, Sabbagh MS, Beach TG. Chemical and neuropathological analyses of an Alzheimer's disease patient treated with solanezumab. American Journal of Neurodegenerative Disease. 5: 158-170. PMID 27725918  0.573
2016 Dugger BN, Whiteside CM, Maarouf CL, Walker DG, Beach TG, Sue LI, Garcia A, Dunckley T, Meechoovet B, Reiman EM, Roher AE. The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 54: 1249. PMID 27716678 DOI: 10.3233/JAD-169007  0.301
2016 Nguyen TV, Frye JB, Zbesko JC, Stepanovic K, Hayes M, Urzua A, Serrano G, Beach TG, Doyle KP. Erratum to: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. Acta Neuropathologica Communications. 4: 104. PMID 27669748 DOI: 10.1186/s40478-016-0376-6  0.416
2016 Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, ... ... Beach TG, et al. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging. PMID 27666590 DOI: 10.1016/J.Neurobiolaging.2016.08.023  0.537
2016 Nguyen TV, Frye JB, Zbesko JC, Stepanovic K, Hayes M, Urzua A, Serrano G, Beach TG, Doyle KP. Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. Acta Neuropathologica Communications. 4: 100. PMID 27600707 DOI: 10.1186/S40478-016-0371-Y  0.424
2016 Beach TG, Corbillé AG, Letournel F, Kordower JH, Kremer T, Munoz DG, Intorcia A, Hentz J, Adler CH, Sue LI, Walker J, Serrano G, Derkinderen P. Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects. Journal of Parkinson's Disease. PMID 27589538 DOI: 10.3233/Jpd-160888  0.539
2016 Chen Y, Liu C, Parker WD, Chen H, Beach TG, Liu X, Serrano GE, Lu Y, Huang J, Yang K, Wang C. Mitochondrial DNA Rearrangement Spectrum in Brain Tissue of Alzheimer's Disease: Analysis of 13 Cases. Plos One. 11: e0154582. PMID 27299301 DOI: 10.1371/journal.pone.0154582  0.562
2016 Filon JR, Intorcia AJ, Sue LI, Vazquez Arreola E, Wilson J, Davis KJ, Sabbagh MN, Belden CM, Caselli RJ, Adler CH, Woodruff BK, Rapscak SZ, Ahern GL, Burke AD, Jacobson S, ... ... Beach TG, et al. Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition. Journal of Neuropathology and Experimental Neurology. PMID 27297671 DOI: 10.1093/jnen/nlw047  0.573
2016 Walker DG, Whetzel AM, Serrano G, Sue LI, Lue LF, Beach TG. Characterization of RNA isolated from eighteen different human tissues: results from a rapid human autopsy program. Cell and Tissue Banking. PMID 27083469 DOI: 10.1007/s10561-016-9555-8  0.439
2016 Hoss AG, Labadorf A, Beach TG, Latourelle JC, Myers RH. microRNA Profiles in Parkinson's Disease Prefrontal Cortex. Frontiers in Aging Neuroscience. 8: 36. PMID 26973511 DOI: 10.3389/Fnagi.2016.00036  0.301
2016 Dugger BN, Whiteside CM, Maarouf CL, Walker DG, Beach TG, Sue LI, Garcia A, Dunckley T, Meechoovet B, Reiman EM, Roher AE. The Presence of Select Tau Speciesin Human Peripheral Tissues and Their Relation to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26890756 DOI: 10.3233/Jad-150859  0.332
2016 Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26799362 DOI: 10.1002/Mds.26476  0.502
2016 Beach TG, Adler CH, Serrano G, Sue LI, Walker DG, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Intorcia A, Filon J, Scott S, Garcia A, Hoffman B, Belden CM, et al. Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders. Journal of Parkinson's Disease. PMID 26756744 DOI: 10.3233/Jpd-150680  0.553
2015 Shill HA, Hentz JG, Caviness JN, Driver-Dunckley E, Jacobson S, Belden C, Sabbagh MN, Beach TG, Adler CH. Unawareness of Hyposmia in Elderly People With and Without Parkinson's Disease. Movement Disorders Clinical Practice. 3: 43-47. PMID 30363525 DOI: 10.1002/mdc3.12220  0.3
2015 Walker DG, Lue LF, Serrano G, Adler CH, Caviness JN, Sue LI, Beach TG. Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases. Frontiers in Neuroscience. 9: 507. PMID 26834537 DOI: 10.3389/fnins.2015.00507  0.546
2015 Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, ... ... Beach TG, et al. Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathologica. PMID 26721587 DOI: 10.1007/S00401-015-1526-9  0.371
2015 Truran S, Weissig V, Madine J, Davies HA, Guzman-Villanueva D, Franco DA, Karamanova N, Burciu C, Serrano G, Beach TG, Migrino RQ. Nanoliposomes protect against human arteriole endothelial dysfunction induced by β-amyloid peptide. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661197 DOI: 10.1177/0271678X15610134  0.515
2015 Janelidze S, Lindqvist D, Francardo V, Hall S, Zetterberg H, Blennow K, Adler CH, Beach TG, Serrano GE, van Westen D, Londos E, Cenci MA, Hansson O. Increased CSF biomarkers of angiogenesis in Parkinson disease. Neurology. PMID 26511451 DOI: 10.1212/Wnl.0000000000002151  0.533
2015 Bien-Ly N, Boswell CA, Jeet S, Beach TG, Hoyte K, Luk W, Shihadeh V, Ulufatu S, Foreman O, Lu Y, DeVoss J, van der Brug M, Watts RJ. Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron. 88: 289-97. PMID 26494278 DOI: 10.1016/J.Neuron.2015.09.036  0.312
2015 Iacono D, Geraci-Erck M, Rabin ML, Adler CH, Serrano G, Beach TG, Kurlan R. Parkinson disease and incidental Lewy body disease: Just a question of time? Neurology. 85: 1670-9. PMID 26468408 DOI: 10.1212/WNL.0000000000002102  0.555
2015 Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492  0.348
2015 Monsell SE, Kukull WA, Roher AE, Maarouf CL, Serrano G, Beach TG, Caselli RJ, Montine TJ, Reiman EM. Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques. Jama Neurology. PMID 26302353 DOI: 10.1001/Jamaneurol.2015.1721  0.564
2015 Dugger BN, Davis K, Malek-Ahmadi M, Hentz JG, Sandhu S, Beach TG, Adler CH, Caselli RJ, Johnson TA, Serrano GE, Shill HA, Belden C, Driver-Dunckley E, Caviness JN, Sue LI, et al. Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment. Bmc Neurology. 15: 146. PMID 26289075 DOI: 10.1186/S12883-015-0403-4  0.552
2015 Postuma RB, Adler CH, Dugger BN, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Jacobson SA, Belden CM, Sue LI, Serrano G, Beach TG. REM sleep behavior disorder and neuropathology in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1413-7. PMID 26265105 DOI: 10.1002/Mds.26347  0.513
2015 Serrano GE, Intorcia A, Carew J, Chiarolanza G, Hidalgo JA, Sue LI, Dugger BN, Saxon-LaBelle M, Filon J, Scroggins A, Pullen J, Fornwalt BE, Scott S, Sabbagh MN, Adler CH, ... ... Beach TG, et al. Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases. Journal of Neuropathology and Experimental Neurology. 74: 934-42. PMID 26230581 DOI: 10.1097/Nen.0000000000000235  0.511
2015 Sabri O, Sabbagh MN, Seibyl J, Barthel H, Akatsu H, Ouchi Y, Senda K, Murayama S, Ishii K, Takao M, Beach TG, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, et al. Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer disease: Phase 3 study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25824567 DOI: 10.1016/j.jalz.2015.02.004  0.309
2015 Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/S00401-015-1407-2  0.367
2015 Kato T, Konishi Y, Shimohama S, Beach TG, Akatsu H, Tooyama I. Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Neuroscience Letters. 591: 19-24. PMID 25676811 DOI: 10.1016/J.Neulet.2015.02.013  0.346
2015 Curtis C, Gamez JE, Singh U, Sadowsky CH, Villena T, Sabbagh MN, Beach TG, Duara R, Fleisher AS, Frey KA, Walker Z, Hunjan A, Holmes C, Escovar YM, Vera CX, et al. Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density. Jama Neurology. 72: 287-94. PMID 25622185 DOI: 10.1001/Jamaneurol.2014.4144  0.305
2015 Beach TG, Adler CH, Sue LI, Serrano G, Shill HA, Walker DG, Lue L, Roher AE, Dugger BN, Maarouf C, Birdsill AC, Intorcia A, Saxon-Labelle M, Pullen J, Scroggins A, et al. Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 35: 354-89. PMID 25619230 DOI: 10.1111/Neup.12189  0.531
2015 Han P, Caselli RJ, Baxter L, Serrano G, Yin J, Beach TG, Reiman EM, Shi J. Association of pituitary adenylate cyclase-activating polypeptide with cognitive decline in mild cognitive impairment due to Alzheimer disease. Jama Neurology. 72: 333-9. PMID 25599520 DOI: 10.1001/jamaneurol.2014.3625  0.569
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Beach TG, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.329
2015 Walker DG, Whetzel AM, Serrano G, Sue LI, Beach TG, Lue LF. Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex. Neurobiology of Aging. 36: 571-82. PMID 25448602 DOI: 10.1016/j.neurobiolaging.2014.09.023  0.529
2015 Sekar S, McDonald J, Cuyugan L, Aldrich J, Kurdoglu A, Adkins J, Serrano G, Beach TG, Craig DW, Valla J, Reiman EM, Liang WS. Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes. Neurobiology of Aging. 36: 583-91. PMID 25448601 DOI: 10.1016/j.neurobiolaging.2014.09.027  0.57
2015 Lue LF, Schmitz CT, Serrano G, Sue LI, Beach TG, Walker DG. TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices. Brain Pathology (Zurich, Switzerland). 25: 469-80. PMID 25186950 DOI: 10.1111/bpa.12190  0.594
2014 Roher AE, Maarouf CL, Kokjohn TA, Whiteside CM, Kalback WM, Serrano G, Belden C, Liebsack C, Jacobson SA, Sabbagh MN, Beach TG. Neuropathological and biochemical assessments of an Alzheimer's disease patient treated with the γ-secretase inhibitor semagacestat. American Journal of Neurodegenerative Disease. 3: 115-33. PMID 25628963  0.57
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.379
2014 Beach TG, Schneider JA, Sue LI, Serrano G, Dugger BN, Monsell SE, Kukull W. Theoretical impact of Florbetapir (18F) amyloid imaging on diagnosis of alzheimer dementia and detection of preclinical cortical amyloid. Journal of Neuropathology and Experimental Neurology. 73: 948-53. PMID 25192053 DOI: 10.1097/Nen.0000000000000114  0.555
2014 Driver-Dunckley E, Adler CH, Hentz JG, Dugger BN, Shill HA, Caviness JN, Sabbagh MN, Beach TG. Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease. Parkinsonism & Related Disorders. 20: 1260-2. PMID 25172126 DOI: 10.1016/J.Parkreldis.2014.08.006  0.31
2014 Maarouf CL, Kokjohn TA, Walker DG, Whiteside CM, Kalback WM, Whetzel A, Sue LI, Serrano G, Jacobson SA, Sabbagh MN, Reiman EM, Beach TG, Roher AE. Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease. Plos One. 9: e105784. PMID 25166759 DOI: 10.1371/journal.pone.0105784  0.542
2014 Truran S, Franco DA, Roher AE, Beach TG, Burciu C, Serrano G, Maarouf CL, Schwab S, Anderson J, Georges J, Reaven P, Migrino RQ. Adipose and leptomeningeal arteriole endothelial dysfunction induced by β-amyloid peptide: a practical human model to study Alzheimer's disease vasculopathy. Journal of Neuroscience Methods. 235: 123-9. PMID 25004204 DOI: 10.1016/J.Jneumeth.2014.06.014  0.55
2014 Serrano GE, Sabbagh MN, Sue LI, Hidalgo JA, Schneider JA, Bedell BJ, Van Deerlin VM, Suh E, Akiyama H, Joshi AD, Pontecorvo MJ, Mintun MA, Beach TG. Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions. Journal of Alzheimer's Disease : Jad. 42: 813-21. PMID 24927705 DOI: 10.3233/Jad-140162  0.578
2014 Beach TG, Carew J, Serrano G, Adler CH, Shill HA, Sue LI, Sabbagh MN, Akiyama H, Cuenca N. Phosphorylated α-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects. Neuroscience Letters. 571: 34-8. PMID 24785101 DOI: 10.1016/j.neulet.2014.04.027  0.522
2014 Han P, Tang Z, Yin J, Maalouf M, Beach TG, Reiman EM, Shi J. Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity. Neurobiology of Aging. 35: 2064-71. PMID 24726470 DOI: 10.1016/j.neurobiolaging.2014.03.022  0.321
2014 Han P, Liang W, Baxter LC, Yin J, Tang Z, Beach TG, Caselli RJ, Reiman EM, Shi J. Pituitary adenylate cyclase-activating polypeptide is reduced in Alzheimer disease. Neurology. 82: 1724-8. PMID 24719484 DOI: 10.1212/WNL.0000000000000417  0.367
2014 Adler CH, Dugger BN, Hinni ML, Lott DG, Driver-Dunckley E, Hidalgo J, Henry-Watson J, Serrano G, Sue LI, Nagel T, Duffy A, Shill HA, Akiyama H, Walker DG, Beach TG. Submandibular gland needle biopsy for the diagnosis of Parkinson disease. Neurology. 82: 858-64. PMID 24500652 DOI: 10.1212/Wnl.0000000000000204  0.537
2014 Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. Journal of Neuropathology and Experimental Neurology. 73: 244-52. PMID 24487796 DOI: 10.1097/Nen.0000000000000046  0.35
2014 Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, Doraiswamy PM, Lu M, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Zehntner SP, Carpenter AP, ... ... Beach TG, et al. Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates. Journal of Neuropathology and Experimental Neurology. 73: 72-80. PMID 24335535 DOI: 10.1097/Nen.0000000000000028  0.561
2013 Maarouf CL, Kokjohn TA, Whiteside CM, Macias MP, Kalback WM, Sabbagh MN, Beach TG, Vassar R, Roher AE. Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis. Biochemistry Insights. 6: 1-10. PMID 25210460 DOI: 10.4137/BCI.S13025  0.311
2013 Roher AE, Maarouf CL, Malek-Ahmadi M, Wilson J, Kokjohn TA, Daugs ID, Whiteside CM, Kalback WM, Macias MP, Jacobson SA, Sabbagh MN, Ghetti B, Beach TG. Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations. American Journal of Neurodegenerative Disease. 2: 187-207. PMID 24093083  0.328
2013 van Blitterswijk M, DeJesus-Hernandez M, Niemantsverdriet E, Murray ME, Heckman MG, Diehl NN, Brown PH, Baker MC, Finch NA, Bauer PO, Serrano G, Beach TG, Josephs KA, Knopman DS, Petersen RC, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. The Lancet. Neurology. 12: 978-88. PMID 24011653 DOI: 10.1016/S1474-4422(13)70210-2  0.515
2013 Sabbagh MN, Malek-Ahmadi M, Dugger BN, Lee K, Sue LI, Serrano G, Walker DG, Davis K, Jacobson SA, Beach TG. The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease. Bmc Neurology. 13: 44. PMID 23663404 DOI: 10.1186/1471-2377-13-44  0.605
2013 Malek-Ahmadi M, Beach T, Obradov A, Sue L, Belden C, Davis K, Walker DG, Lue L, Adem A, Sabbagh MN. Increased Alzheimer's disease neuropathology is associated with type 2 diabetes and ApoE ε.4 carrier status. Current Alzheimer Research. 10: 654-9. PMID 23627755 DOI: 10.2174/15672050113109990006  0.326
2013 Arnold SJ, Dugger BN, Beach TG. TDP-43 deposition in prospectively followed, cognitively normal elderly individuals: correlation with argyrophilic grains but not other concomitant pathologies. Acta Neuropathologica. 126: 51-7. PMID 23604587 DOI: 10.1007/S00401-013-1110-0  0.335
2013 Davies P, Hinkle KM, Sukar NN, Sepulveda B, Mesias R, Serrano G, Alessi DR, Beach TG, Benson DL, White CL, Cowell RM, Das SS, West AB, Melrose HL. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies. The Biochemical Journal. 453: 101-13. PMID 23560750 DOI: 10.1042/Bj20121742  0.472
2013 Roher AE, Cribbs DH, Kim RC, Maarouf CL, Whiteside CM, Kokjohn TA, Daugs ID, Head E, Liebsack C, Serrano G, Belden C, Sabbagh MN, Beach TG. Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy. Plos One. 8: e59735. PMID 23555764 DOI: 10.1371/journal.pone.0059735  0.569
2013 Maarouf CL, Beach TG, Adler CH, Malek-Ahmadi M, Kokjohn TA, Dugger BN, Walker DG, Shill HA, Jacobson SA, Sabbagh MN, Roher AE. Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology. Biomarker Insights. 8: 19-28. PMID 23533154 DOI: 10.4137/Bmi.S11422  0.387
2013 Beach TG, Adler CH, Dugger BN, Serrano G, Hidalgo J, Henry-Watson J, Shill HA, Sue LI, Sabbagh MN, Akiyama H. Submandibular gland biopsy for the diagnosis of Parkinson disease. Journal of Neuropathology and Experimental Neurology. 72: 130-6. PMID 23334596 DOI: 10.1097/Nen.0B013E3182805C72  0.554
2013 Kokjohn TA, Maarouf CL, Daugs ID, Hunter JM, Whiteside CM, Malek-Ahmadi M, Rodriguez E, Kalback W, Jacobson SA, Sabbagh MN, Beach TG, Roher AE. Neurochemical profile of dementia pugilistica. Journal of Neurotrauma. 30: 981-97. PMID 23268705 DOI: 10.1089/Neu.2012.2699  0.364
2013 Walker DG, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG. Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains. Experimental Neurology. 240: 190-204. PMID 23201181 DOI: 10.1016/j.expneurol.2012.11.020  0.53
2013 Decourt B, Gonzales A, Beach TG, Malek-Ahmadi M, Walker A, Sue L, Walker DG, Sabbagh MN. BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains. Current Alzheimer Research. 10: 309-15. PMID 23036023 DOI: 10.2174/1567205011310030010  0.315
2012 Roher AE, Debbins JP, Malek-Ahmadi M, Chen K, Pipe JG, Maze S, Belden C, Maarouf CL, Thiyyagura P, Mo H, Hunter JM, Kokjohn TA, Walker DG, Kruchowsky JC, Belohlavek M, ... ... Beach TG, et al. Cerebral blood flow in Alzheimer's disease. Vascular Health and Risk Management. 8: 599-611. PMID 23109807 DOI: 10.2147/Vhrm.S34874  0.372
2012 Dugger BN, Serrano GE, Sue LI, Walker DG, Adler CH, Shill HA, Sabbagh MN, Caviness JN, Hidalgo J, Saxon-Labelle M, Chiarolanza G, Mariner M, Henry-Watson J, Beach TG. Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging. Journal of Parkinson's Disease. 2: 57-65. PMID 22924088 DOI: 10.3233/Jpd-2012-11073  0.631
2012 Hunter JM, Kwan J, Malek-Ahmadi M, Maarouf CL, Kokjohn TA, Belden C, Sabbagh MN, Beach TG, Roher AE. Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease. Plos One. 7: e36893. PMID 22615835 DOI: 10.1371/Journal.Pone.0036893  0.379
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Beach TG, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.337
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, ... ... Beach TG, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7  0.336
2012 Prasad K, Beach TG, Hedreen J, Richfield EK. Critical role of truncated α-synuclein and aggregates in Parkinson's disease and incidental Lewy body disease. Brain Pathology (Zurich, Switzerland). 22: 811-25. PMID 22452578 DOI: 10.1111/J.1750-3639.2012.00597.X  0.303
2012 Beach TG, Monsell SE, Phillips LE, Kukull W. Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010. Journal of Neuropathology and Experimental Neurology. 71: 266-73. PMID 22437338 DOI: 10.1097/NEN.0b013e31824b211b  0.377
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/J.Jalz.2011.10.007  0.407
2012 Beach TG, Sue LI, Walker DG, Sabbagh MN, Serrano G, Dugger BN, Mariner M, Yantos K, Henry-Watson J, Chiarolanza G, Hidalgo JA, Souders L. Striatal amyloid plaque density predicts Braak neurofibrillary stage and clinicopathological Alzheimer's disease: implications for amyloid imaging. Journal of Alzheimer's Disease : Jad. 28: 869-76. PMID 22112552 DOI: 10.3233/Jad-2011-111340  0.583
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/S00401-011-0910-3  0.388
2011 Maarouf CL, Daugs ID, Kokjohn TA, Walker DG, Hunter JM, Kruchowsky JC, Woltjer R, Kaye J, Castaño EM, Sabbagh MN, Beach TG, Roher AE. Alzheimer's disease and non-demented high pathology control nonagenarians: comparing and contrasting the biochemistry of cognitively successful aging. Plos One. 6: e27291. PMID 22087282 DOI: 10.1371/journal.pone.0027291  0.376
2011 Hunter JM, Bowers WJ, Maarouf CL, Mastrangelo MA, Daugs ID, Kokjohn TA, Kalback WM, Luehrs DC, Valla J, Beach TG, Roher AE. Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 361-76. PMID 21860086 DOI: 10.3233/Jad-2011-110608  0.338
2011 Caviness JN, Lue LF, Beach TG, Hentz JG, Adler CH, Sue L, Sadeghi R, Driver-Dunckley E, Evidente VG, Sabbagh MN, Shill HA, Walker DG. Parkinson's disease, cortical dysfunction, and alpha-synuclein. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1436-42. PMID 21542019 DOI: 10.1002/mds.23697  0.307
2011 Potter PE, Rauschkolb PK, Pandya Y, Sue LI, Sabbagh MN, Walker DG, Beach TG. Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease. Acta Neuropathologica. 122: 49-60. PMID 21533854 DOI: 10.1007/s00401-011-0831-1  0.337
2011 Roher AE, Tyas SL, Maarouf CL, Daugs ID, Kokjohn TA, Emmerling MR, Garami Z, Belohlavek M, Sabbagh MN, Sue LI, Beach TG. Intracranial atherosclerosis as a contributing factor to Alzheimer's disease dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 436-44. PMID 21388893 DOI: 10.1016/j.jalz.2010.08.228  0.352
2011 Roher AE, Garami Z, Tyas SL, Maarouf CL, Kokjohn TA, Belohlavek M, Vedders LJ, Connor D, Sabbagh MN, Beach TG, Emmerling MR. Transcranial doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 445-55. PMID 21388892 DOI: 10.1016/j.jalz.2010.09.002  0.324
2011 Morimoto K, Horio J, Satoh H, Sue L, Beach T, Arita S, Tooyama I, Konishi Y. Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology. Journal of Alzheimer's Disease : Jad. 25: 59-76. PMID 21368376 DOI: 10.3233/JAD-2011-101815  0.333
2011 Adler CH, Shill HA, Beach TG. Essential tremor and Parkinson's disease: lack of a link. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 372-7. PMID 21284040 DOI: 10.1002/mds.23509  0.304
2011 Beach TG, Maarouf CL, Brooks RG, Shirohi S, Daugs ID, Sue LI, Sabbagh MN, Walker DG, Lue L, Roher AE. Reduced clinical and postmortem measures of cardiac pathology in subjects with advanced Alzheimer's Disease. Bmc Geriatrics. 11: 3. PMID 21266042 DOI: 10.1186/1471-2318-11-3  0.357
2011 Roher AE, Maarouf CL, Daugs ID, Kokjohn TA, Hunter JM, Sabbagh MN, Beach TG. Neuropathology and amyloid-β spectrum in a bapineuzumab immunotherapy recipient. Journal of Alzheimer's Disease : Jad. 24: 315-25. PMID 21263194 DOI: 10.3233/JAD-2011-101809  0.312
2010 Maarouf CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Masliah E, Nicoll JA, Sabbagh MN, Beach TG, Castaño EM, Roher AE. The biochemical aftermath of anti-amyloid immunotherapy. Molecular Neurodegeneration. 5: 39. PMID 20929585 DOI: 10.1186/1750-1326-5-39  0.325
2010 Valla J, Yaari R, Wolf AB, Kusne Y, Beach TG, Roher AE, Corneveaux JJ, Huentelman MJ, Caselli RJ, Reiman EM. Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene. Journal of Alzheimer's Disease : Jad. 22: 307-13. PMID 20847408 DOI: 10.3233/Jad-2010-100129  0.303
2010 Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, ... Beach TG, et al. Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiology of Aging. 31: 901-9. PMID 18789830 DOI: 10.1016/J.Neurobiolaging.2008.07.014  0.307
2010 Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. Neurobiology of Aging. 31: 549-66. PMID 18572275 DOI: 10.1016/J.Neurobiolaging.2008.05.013  0.367
2009 Roher AE, Maarouf CL, Sue LI, Hu Y, Wilson J, Beach TG. Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 14: 493-501. PMID 19863188 DOI: 10.3109/13547500903108423  0.31
2009 Sabbagh MN, Adler CH, Lahti TJ, Connor DJ, Vedders L, Peterson LK, Caviness JN, Shill HA, Sue LI, Ziabreva I, Perry E, Ballard CG, Aarsland D, Walker DG, Beach TG. Parkinson disease with dementia: comparing patients with and without Alzheimer pathology. Alzheimer Disease and Associated Disorders. 23: 295-7. PMID 19812474 DOI: 10.1097/Wad.0B013E31819C5Ef4  0.388
2009 Maarouf CL, Andacht TM, Kokjohn TA, Castaño EM, Sue LI, Beach TG, Roher AE. Proteomic analysis of Alzheimer's disease cerebrospinal fluid from neuropathologically diagnosed subjects. Current Alzheimer Research. 6: 399-406. PMID 19689240  0.32
2009 Thompson PW, Ye L, Morgenstern JL, Sue L, Beach TG, Judd DJ, Shipley NJ, Libri V, Lockhart A. Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer's disease pathologies. Journal of Neurochemistry. 109: 623-30. PMID 19226369 DOI: 10.1111/j.1471-4159.2009.05996.x  0.327
2009 Beach TG, White CL, Hladik CL, Sabbagh MN, Connor DJ, Shill HA, Sue LI, Sasse J, Bachalakuri J, Henry-Watson J, Akiyama H, Adler CH. Olfactory bulb alpha-synucleinopathy has high specificity and sensitivity for Lewy body disorders. Acta Neuropathologica. 117: 169-74. PMID 18982334 DOI: 10.1007/s00401-008-0450-7  0.305
2008 Stamper C, Siegel A, Liang WS, Pearson JV, Stephan DA, Shill H, Connor D, Caviness JN, Sabbagh M, Beach TG, Adler CH, Dunckley T. Neuronal gene expression correlates of Parkinson's disease with dementia. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 1588-95. PMID 18649390 DOI: 10.1002/mds.22184  0.315
2008 Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiological Genomics. 33: 240-56. PMID 18270320 DOI: 10.1152/Physiolgenomics.00242.2007  0.337
2008 Webster JA, Myers AJ, Pearson JV, Craig DW, Hu-Lince D, Coon KD, Zismann VL, Beach T, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Huentelman MJ, Joshipura K, et al. Sorl1 as an Alzheimer's disease predisposition gene? Neuro-Degenerative Diseases. 5: 60-4. PMID 17975299 DOI: 10.1159/000110789  0.326
2007 Weeraratna AT, Kalehua A, Deleon I, Bertak D, Maher G, Wade MS, Lustig A, Becker KG, Wood W, Walker DG, Beach TG, Taub DD. Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Experimental Cell Research. 313: 450-61. PMID 17188679 DOI: 10.1016/j.yexcr.2006.10.028  0.315
2007 Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette C, Schmechel D, Alexander GE, Reiman EM, Rogers J, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiological Genomics. 28: 311-22. PMID 17077275 DOI: 10.1152/Physiolgenomics.00208.2006  0.303
2007 Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiology of Aging. 28: 1821-33. PMID 17052803 DOI: 10.1016/J.Neurobiolaging.2006.08.014  0.343
2007 Beach TG, Wilson JR, Sue LI, Newell A, Poston M, Cisneros R, Pandya Y, Esh C, Connor DJ, Sabbagh M, Walker DG, Roher AE. Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles. Acta Neuropathologica. 113: 13-21. PMID 17021755 DOI: 10.1007/s00401-006-0136-y  0.352
2006 Sabbagh MN, Farlow MR, Relkin N, Beach TG. Do cholinergic therapies have disease-modifying effects in Alzheimer's disease? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 118-25. PMID 19595868 DOI: 10.1016/J.Jalz.2006.02.001  0.334
2006 Caselli RJ, Beach TG, Yaari R, Reiman EM. Alzheimer's disease a century later. The Journal of Clinical Psychiatry. 67: 1784-800. PMID 17196061  0.35
2006 Sabbagh MN, Shah F, Reid RT, Sue L, Connor DJ, Peterson LK, Beach TG. Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging. Archives of Neurology. 63: 1771-6. PMID 17172618 DOI: 10.1001/archneur.63.12.1771  0.301
2006 Roher AE, Garami Z, Alexandrov AV, Kokjohn TA, Esh CL, Kalback WM, Vedders LJ, Wilson JR, Sabbagh MN, Beach TG. Interaction of cardiovascular disease and neurodegeneration: transcranial Doppler ultrasonography and Alzheimer's disease. Neurological Research. 28: 672-8. PMID 16945221 DOI: 10.1179/016164106X130470  0.311
2006 Castaño EM, Roher AE, Esh CL, Kokjohn TA, Beach T. Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects. Neurological Research. 28: 155-63. PMID 16551433 DOI: 10.1179/016164106X98035  0.369
2006 Roher AE, Kokjohn TA, Beach TG. An association with great implications: vascular pathology and Alzheimer disease. Alzheimer Disease and Associated Disorders. 20: 73-5. PMID 16493240 DOI: 10.1097/01.wad.0000201855.39246.2d  0.334
2004 Kalback W, Esh C, Castaño EM, Rahman A, Kokjohn T, Luehrs DC, Sue L, Cisneros R, Gerber F, Richardson C, Bohrmann B, Walker DG, Beach TG, Roher AE. Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease. Neurological Research. 26: 525-39. PMID 15265270 DOI: 10.1179/016164104225017668  0.311
2003 Beach TG, Sue L, Scott S, Layne K, Newell A, Walker D, Baker M, Sahara N, Yen SH, Hutton M, Caselli R, Adler C, Connor D, Sabbagh M. Hippocampal sclerosis dementia with tauopathy. Brain Pathology (Zurich, Switzerland). 13: 263-78. PMID 12946017 DOI: 10.1111/J.1750-3639.2003.Tb00027.X  0.309
2003 Konishi Y, Beach T, Sue LI, Hampel H, Lindholm K, Shen Y. The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology. Neuroscience Letters. 348: 46-50. PMID 12893422 DOI: 10.1016/s0304-3940(03)00567-6  0.338
2003 Roher AE, Kuo YM, Esh C, Knebel C, Weiss N, Kalback W, Luehrs DC, Childress JL, Beach TG, Weller RO, Kokjohn TA. Cortical and leptomeningeal cerebrovascular amyloid and white matter pathology in Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 9: 112-22. PMID 12865947  0.331
2002 Caselli RJ, Beach TG, Sue LI, Connor DJ, Sabbagh MN. Progressive aphasia with Lewy bodies. Dementia and Geriatric Cognitive Disorders. 14: 55-8. PMID 12145451  0.349
2001 Kuo YM, Kokjohn TA, Beach TG, Sue LI, Brune D, Lopez JC, Kalback WM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Roher AE. Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. The Journal of Biological Chemistry. 276: 12991-8. PMID 11152675 DOI: 10.1074/jbc.M007859200  0.303
1989 Beach TG, Walker R, McGeer EG. Lamina-selective A68 immunoreactivity in primary visual cortex of Alzheimer's disease patients. Brain Research. 501: 171-4. PMID 2804692 DOI: 10.1016/0006-8993(89)91038-X  0.318
1988 Beach TG, McGeer EG. Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex. Brain Research. 463: 357-61. PMID 3196922 DOI: 10.1016/0006-8993(88)90410-6  0.308
1987 Beach TG. The history of Alzheimer's disease: three debates. Journal of the History of Medicine and Allied Sciences. 42: 327-49. PMID 3305698  0.351
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