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Nigel J. Cairns, PhD, FRCP - Publications

Affiliations: 
Pathology, Neurology and Immunology Washington University, Saint Louis, St. Louis, MO 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=97
Website:
http://neuro.wustl.edu/aboutus/facultybiographies/cairns.htm

328 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vöglein J, Franzmeier N, Morris JC, Dieterich M, McDade E, Simons M, Preische O, Hofmann A, Hassenstab J, Benzinger TL, Fagan A, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, ... ... Cairns N, et al. Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35609137 DOI: 10.1002/alz.12684  0.33
2022 Morris JC, Weiner M, Xiong C, Beckett L, Coble D, Saito N, Aisen PS, Allegri R, Benzinger TLS, Berman SB, Cairns NJ, Carrillo MC, Chui HC, Chhatwal JP, Cruchaga C, et al. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a Journal of Neurology. PMID 35580594 DOI: 10.1093/brain/awac181  0.414
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Cairns NJ, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.34
2021 Arezoumandan S, Cai X, Kalkarni P, Davis SM, Wilson K, Ferris CF, Cairns NJ, Gitcho MA. Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background. Neuroscience Letters. 136010. PMID 34090937 DOI: 10.1016/j.neulet.2021.136010  0.327
2020 Hannon E, Shireby GL, Brookes K, Attems J, Sims R, Cairns NJ, Love S, Thomas AJ, Morgan K, Francis PT, Mill J. Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways. Brain Communications. 2: fcaa167. PMID 33376986 DOI: 10.1093/braincomms/fcaa167  0.37
2020 Chen CD, Holden TR, Gordon BA, Franklin EE, Li Y, Coble DW, Luo H, Bateman RJ, Ances BM, Perrin RJ, Benzinger TLS, Cairns NJ, Morris JC. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 33150749 DOI: 10.1002/acn3.51237  0.389
2020 Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, ... ... Cairns NJ, et al. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications. 8: 5. PMID 31996268 DOI: 10.1186/S40478-020-0879-Z  0.457
2019 Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, ... ... Cairns NJ, et al. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. PMID 31631020 DOI: 10.1016/J.Stemcr.2019.09.006  0.374
2019 Del-Aguila JL, Benitez BA, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Farias FHG, Fernández MV, Ibanez L, Jiang S, Perrin RJ, Cairns NJ, Morris JC, Harari O, Cruchaga C. TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers. Molecular Neurodegeneration. 14: 18. PMID 31068200 DOI: 10.1186/S13024-019-0319-3  0.423
2019 Wang Q, Wang Y, Liu J, Sutphen CL, Cruchaga C, Blazey T, Gordon BA, Su Y, Chen C, Shimony JS, Ances BM, Cairns NJ, Fagan AM, Morris JC, Benzinger TLS. Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease. Neuroimage. Clinical. 22: 101767. PMID 30901713 DOI: 10.1016/J.Nicl.2019.101767  0.417
2019 Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, ... ... Cairns N, et al. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30897203 DOI: 10.1093/Brain/Awz050  0.412
2019 Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, ... ... Cairns NJ, et al. Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers. Brain : a Journal of Neurology. PMID 30753379 DOI: 10.1093/Brain/Awz019  0.486
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Cairns NJ, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9  0.317
2019 Joseph-Mathurin N, Perrin RJ, Cairns NJ, Franklin EE, Xiong C, Preboske GM, Jack CR, Morris JC, Bateman R, Benzinger TLS. Ic-P-046: Cerebral Amyloid Angiopathy Is More Severe In Autosomal Dominant Ad Cases With Cerebral Microhemorrhages: Results From The Dian Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4208  0.364
2018 Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ. Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 30564964 DOI: 10.1007/S10072-018-3686-6  0.443
2018 Jiang S, Wen N, Li Z, Dube U, Del Aguila J, Budde J, Martinez R, Hsu S, Fernandez MV, Cairns NJ, Harari O, Cruchaga C, Karch CM. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Translational Psychiatry. 8: 265. PMID 30546007 DOI: 10.1038/S41398-018-0319-Z  0.363
2018 Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, ... ... Cairns NJ, et al. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiology of Aging. PMID 30448004 DOI: 10.1016/J.Neurobiolaging.2018.10.019  0.375
2018 Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Tick-Chong MS, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, et al. Distinct cytokine profiles in human brains resilient to Alzheimer's pathology. Neurobiology of Disease. PMID 30336198 DOI: 10.1016/J.Nbd.2018.10.009  0.448
2018 Veitch DP, Weiner MW, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ, et al. Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321505 DOI: 10.1016/J.Jalz.2018.08.005  0.463
2018 Schultz SA, Gordon BA, Mishra S, Su Y, Perrin RJ, Cairns NJ, Morris JC, Ances BM, Benzinger TLS. Widespread distribution of tauopathy in preclinical Alzheimer's disease. Neurobiology of Aging. 72: 177-185. PMID 30292840 DOI: 10.1016/J.Neurobiolaging.2018.08.022  0.396
2018 Ihara R, Vincent BD, Baxter MR, Franklin EE, Hassenstab JJ, Xiong C, Morris JC, Cairns NJ. Relative neuron loss in hippocampal sclerosis of aging and Alzheimer disease. Annals of Neurology. PMID 30246887 DOI: 10.1002/Ana.25344  0.349
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277  0.334
2018 Esparza TJ, Gangolli M, Cairns NJ, Brody DL. Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls. Plos One. 13: e0200251. PMID 29979775 DOI: 10.1371/Journal.Pone.0200251  0.31
2018 Besser LM, Kukull WA, Teylan MA, Bigio EH, Cairns NJ, Kofler JK, Montine TJ, Schneider JA, Nelson PT. The Revised National Alzheimer's Coordinating Center's Neuropathology Form-Available Data and New Analyses. Journal of Neuropathology and Experimental Neurology. PMID 29945202 DOI: 10.1093/Jnen/Nly049  0.436
2018 Li Z, Del-Aguila JL, Dube U, Budde J, Martinez R, Black K, Xiao Q, Cairns NJ, Dougherty JD, Lee JM, Morris JC, Bateman RJ, Karch CM, Cruchaga C, et al. Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure. Genome Medicine. 10: 43. PMID 29880032 DOI: 10.1186/S13073-018-0551-4  0.363
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838  0.362
2018 Wildburger NC, Gyngard F, Guillermier C, Patterson BW, Elbert D, Mawuenyega KG, Schneider T, Green K, Roth R, Schmidt RE, Cairns NJ, Benzinger TLS, Steinhauser ML, Bateman RJ. Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracerand Exhibit Nanoscale Heterogeneity. Frontiers in Neurology. 9: 169. PMID 29623063 DOI: 10.3389/Fneur.2018.00169  0.36
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Cairns NJ, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  0.322
2018 Day GS, Gordon BA, Perrin RJ, Cairns NJ, Beaumont H, Schwetye K, Ferguson C, Sinha N, Bucelli R, Musiek ES, Ghoshal N, Ponisio MR, Vincent B, Mishra S, Jackson K, et al. In vivo [18F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease. Neurology. PMID 29438042 DOI: 10.1212/Wnl.0000000000005064  0.343
2018 Gordon BA, Blazey TM, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Marcus DS, Fagan AM, Jack CR, et al. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. The Lancet. Neurology. PMID 29397305 DOI: 10.1016/S1474-4422(18)30028-0  0.476
2018 Chou CC, Zhang Y, Umoh ME, Vaughan SW, Lorenzini I, Liu F, Sayegh M, Donlin-Asp PG, Chen YH, Duong DM, Seyfried NT, Powers MA, Kukar T, Hales CM, Gearing M, ... Cairns NJ, et al. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature Neuroscience. PMID 29311743 DOI: 10.1038/S41593-017-0047-3  0.372
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, ... ... Cairns NJ, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.384
2018 Vöglein J, Paumier KL, Cairns NJ, Franklin EE, Perrin RJ, Xiong C, Jucker M, Bateman RJ, Danek A, Morris JC, Levin J. P1-497: Clinical Correlates Of Lewy Body Pathology In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.507  0.431
2018 Wang Q, Wang Y, Shimony JS, Liu J, Fagan AM, Cairns NJ, Ances BM, Morris JC, Benzinger TLS. Ic-P-195: Quantification Of White Matter Cellularity In Preclinical And Early Symptomatic Alzheimer Disease Using Neuro-Immnue Imaging Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2262  0.372
2017 Hortobágyi T, Cairns NJ. Amyotrophic lateral sclerosis and non-tau frontotemporal lobar degeneration. Handbook of Clinical Neurology. 145: 369-381. PMID 28987183 DOI: 10.1016/B978-0-12-802395-2.00026-2  0.413
2017 Nilsson P, Shirani H, Appelqvist H, Bäck M, Klingstedt T, Cairns N. Synthesis of thiophene based optical ligands that selectively detect tau pathology in Alzheimer´s disease. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28926133 DOI: 10.1002/Chem.201703846  0.41
2017 Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL. Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. Scientific Reports. 7: 9520. PMID 28842697 DOI: 10.1038/S41598-017-10422-X  0.338
2017 Mishra S, Gordon BA, Su Y, Christensen J, Friedrichsen K, Jackson K, Hornbeck R, Balota DA, Cairns NJ, Morris JC, Ances BM, Benzinger TLS. AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure. Neuroimage. PMID 28756238 DOI: 10.1016/J.Neuroimage.2017.07.050  0.327
2017 Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ, Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T, Masters CL, Weiner M, ... Cairns N, et al. Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28501451 DOI: 10.1016/J.Jalz.2017.03.008  0.431
2017 Yanamandra K, Patel TK, Jiang H, Schindler S, Ulrich JD, Boxer AL, Miller BL, Kerwin DR, Gallardo G, Stewart F, Finn MB, Cairns NJ, Verghese PB, Fogelman I, West T, et al. Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy. Science Translational Medicine. 9. PMID 28424326 DOI: 10.1126/Scitranslmed.Aal2029  0.338
2017 Davis SA, Gan KA, Dowell JA, Cairns NJ, Gitcho MA. TDP-43 expression influences amyloidβ plaque deposition and tau aggregation. Neurobiology of Disease. PMID 28416393 DOI: 10.1016/J.Nbd.2017.04.012  0.443
2017 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ, et al. Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28342697 DOI: 10.1016/J.Jalz.2016.11.007  0.419
2017 Martin WR, Hartlein J, Racette BA, Cairns N, Perlmutter JS. Pathologic correlates of supranuclear gaze palsy with parkinsonism. Parkinsonism & Related Disorders. PMID 28256434 DOI: 10.1016/J.Parkreldis.2017.02.027  0.324
2017 Day GS, Lim TS, Hassenstab J, Goate AM, Grant EA, Roe CM, Cairns NJ, Morris JC. Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease. Neurology. PMID 28235814 DOI: 10.1212/Wnl.0000000000003770  0.426
2017 McDade E, Wang G, Benzinger TL, Buckles VD, Fagan AM, Gordon BA, Hassenstab J, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier KL, Xiong C, Ricardo A, et al. LONGITUDINAL BIOMARKER CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE FROM THE DIAN STUDY Alzheimer's & Dementia. 13: P879-P880. DOI: 10.1016/J.Jalz.2017.07.265  0.442
2017 Cairns NJ, Perrin RJ, Vincent BD, Baxter MR, Franklin EE, Bateman RJ, Morris JC. NEUROPATHOLOGIC HETEROGENEITY IN FAMILIAL AND LATE-ONSET ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P877. DOI: 10.1016/J.Jalz.2017.07.255  0.437
2017 Day GS, Gordon BA, Perrin RJ, Cairns NJ, Schwetye KE, Ferguson CJ, Sinha N, Ponisio MR, Vincent BD, Beaumont H, Bucelli RC, Ghoshal N, Musiek ES, Morris JC, Benzinger TL, et al. FLORTAUCIPIR TAU-PET SPECIFICITY IS MAINTAINED IN PATIENTS WITH PATHOLOGICALLY CONFIRMED CREUTZFELDT-JAKOB DISEASE Alzheimer's & Dementia. 13: P900-P901. DOI: 10.1016/J.Jalz.2017.06.2555  0.403
2017 Yablonskiy DA, Zhao Y, Cairns NJ, Hassenstab J, Benzinger TL, Astafiev SV, Wen J, Raichle ME, Morris JC. [IC-P-169]: GRADIENT ECHO PLURAL CONTRAST MRI PROVIDES NEW SURROGATE MARKERS OF BRAIN PATHOLOGY IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P127-P128. DOI: 10.1016/J.Jalz.2017.06.2544  0.408
2017 Joseph-Mathurin N, Kantarci K, Jack CR, Ringman JM, Salloway S, McDade E, Clifford D, Blazey T, Friedrichsen KA, Su Y, Gordon BA, Hornbeck RC, Mills S, Ances BM, Raichle ME, ... ... Cairns NJ, et al. Clinical Risk Related To Cerebral Microhemorrhages In Autosomal Dominant Alzheimer’S Disease: Longitudinal Results From The Dian Study Alzheimers & Dementia. 13: 47. DOI: 10.1016/J.Jalz.2017.06.2330  0.338
2017 Gordon BA, Blazey T, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Fagan AM, Marcus DS, Jack CR, et al. [IC-P-054]: EXAMINING LONGITUDINAL NEUROIMAGING PATTERNS IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE: RESULTS FROM THE DOMINANTLY INHERITED ALZHEIMER NETWORK Alzheimer's & Dementia. 13: P44-P45. DOI: 10.1016/J.Jalz.2017.06.2327  0.414
2017 Joseph-Mathurin N, Su Y, Blazey T, Jasielec MS, Vlassenko AG, Friedrichsen KA, Gordon BA, Hornbeck RC, Cash L, Ances BM, Raichle ME, Brickman AM, Buckles V, Cairns NJ, Cruchaga C, et al. Utility Of Perfusion Pet Models As Measures Of Neurodegeneration In An Autosomal Dominant Alzheimer’S Disease Population: Report From The Dian Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1027  0.308
2016 Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, et al. Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28017827 DOI: 10.1016/J.Jalz.2016.11.003  0.459
2016 Zhao Y, Raichle ME, Wen J, Benzinger TL, Fagan AM, Hassenstab J, Vlassenko AG, Luo J, Cairns NJ, Christensen JJ, Morris JC, Yablonskiy DA. In vivo Detection of Microstructural Correlates of Brain Pathology in Preclinical and Early Alzheimer Disease with Magnetic Resonance Imaging. Neuroimage. PMID 27989773 DOI: 10.1016/J.Neuroimage.2016.12.026  0.438
2016 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Morris JC, Petersen RC, Salazar J, Saykin AJ, Shaw LM, Toga AW, et al. The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27931796 DOI: 10.1016/J.Jalz.2016.10.006  0.34
2016 Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL. Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains. Scientific Reports. 6: 38187. PMID 27917876 DOI: 10.1038/srep38187  0.426
2016 Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Ellingson SR, Morris JC, Goate AM, Kukull WA. Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology. Alzheimer Disease and Associated Disorders. PMID 27849641 DOI: 10.1097/Wad.0000000000000179  0.457
2016 Sundaram GS, Dhavale DD, Prior JL, Yan P, Cirrito J, Rath NP, Laforest R, Cairns NJ, Lee JM, Kotzbauer PT, Sharma V. Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease. Scientific Reports. 6: 35636. PMID 27805057 DOI: 10.1038/Srep35636  0.434
2016 Baker-Nigh AT, Mawuenyega KG, Bollinger JG, Ovod V, Kasten T, Franklin EE, Liao F, Jiang H, Holtzman D, Cairns NJ, Morris JC, Bateman RJ. Human Central Nervous System (CNS) ApoE Isoforms are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared to Plasma. The Journal of Biological Chemistry. PMID 27793990 DOI: 10.1074/Jbc.M116.721779  0.39
2016 Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, et al. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 27777020 DOI: 10.1016/S1474-4422(16)30229-0  0.412
2016 Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, ... ... Cairns NJ, et al. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging. PMID 27666590 DOI: 10.1016/J.Neurobiolaging.2016.08.023  0.398
2016 Wang L, Benzinger TL, Su Y, Christensen J, Friedrichsen K, Aldea P, McConathy J, Cairns NJ, Fagan AM, Morris JC, Ances BM. Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy. Jama Neurology. PMID 27454922 DOI: 10.1001/Jamaneurol.2016.2078  0.458
2016 Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC. Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study. Jama Neurology. PMID 27454811 DOI: 10.1016/J.Jalz.2016.06.1371  0.341
2016 Gordon BA, Friedrichsen K, Brier M, Blazey T, Su Y, Christensen J, Aldea P, McConathy J, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances BM, Benzinger TL. The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging. Brain : a Journal of Neurology. PMID 27286736 DOI: 10.1093/Brain/Aww139  0.438
2016 Brier MR, Gordon B, Friedrichsen K, McCarthy J, Stern A, Christensen J, Owen C, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, Benzinger TL, et al. Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease. Science Translational Medicine. 8: 338ra66. PMID 27169802 DOI: 10.1126/Scitranslmed.Aaf2362  0.481
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  0.467
2016 Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ. A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy. Neuropathology and Applied Neurobiology. PMID 26998921 DOI: 10.1111/Nan.12323  0.346
2016 Wildburger NC, Esparza TJ, Cairns NJ, Bateman R, Brody DL. P1-100: Amyloid-Beta (Aβ) Isoforms and Ptms of Soluble Aβ Oligomers from Human Brain Alzheimer's & Dementia. 12: P439-P440. DOI: 10.1016/J.Jalz.2016.06.848  0.359
2016 Esparza TJ, Wildburger NC, Cairns NJ, Roth R, Brody DL. P1-099: Purification and Quantitative Characterization of Amyloid-Beta Oligomers from Alzheimer's Disease Brain Lysates Alzheimer's & Dementia. 12: P439-P439. DOI: 10.1016/J.Jalz.2016.06.847  0.423
2016 McDade E, Weng H, Wang G, Xiong C, Fagan AM, Hassenstab J, Marcus DS, Morris JC, Benzinger TL, Cairns NJ, Goate AM, Buckles V, Holtzman DM, Berman S, Ghetti B, et al. O5-02-01: Longitudinal Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease: The Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 12: P378-P379. DOI: 10.1016/J.Jalz.2016.06.710  0.413
2016 Benzinger TLS, Gordon BA, Friedrichsen KA, Su Y, Christensen J, Hornbeck RC, Mishra S, Aldea P, Cash L, Ances B, McConathy J, Koeppe RA, McDade E, Cairns NJ, Morris JC, et al. Tau Pet Imaging With Av-1451 In Autosomal Dominant Alzheimer'S Disease: Update From The Dominantly Inherited Alzheimer Network (Dian) Alzheimers & Dementia. 12: 378. DOI: 10.1016/J.Jalz.2016.06.709  0.444
2016 Lee S, Zimmerman ME, Viqar F, Narkhede A, Tosto G, Lee Smith Benzinger T, Marcus DS, Goate AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, et al. O2-03-02: are White Matter Hyperintensities a Core Feature of Alzheimer’s Disease or Just a Reflection of Amyloid Angiopathy? Evidence From the Dominantly Inherited Alzheimer Network (DIAN) Alzheimer's & Dementia. 12: P226-P226. DOI: 10.1016/J.Jalz.2016.06.406  0.384
2016 Friedrichsen KA, Mishra S, Gordon BA, Ghoshal N, Su Y, Joseph-Mathurin N, Christensen J, Aldea P, McConathy J, Ances B, Cairns NJ, Morris JC, Benzinger TL. IC-P-204: Principal Component Analysis of [18F]-Av-1451 TAU PET in Alzheimer’s Disease and Frontotemporal Dementia Alzheimer's & Dementia. 12: P145-P146. DOI: 10.1016/J.Jalz.2016.06.236  0.361
2016 Wang Q, Wang Y, Christensen J, Shimony JS, Liu J, Fagan AM, Cairns NJ, Ances B, Morris JC, Benzinger TLS. Imaging Marker Of Neuroinflammation Predicts Progression In Alzheimer'S Disease Alzheimers & Dementia. 12: 1076. DOI: 10.1016/J.Jalz.2016.06.2252  0.394
2016 Ances B, Brier MR, Gordon BA, Friedrichsen KA, McCarthy JE, Stern A, Christensen J, Owen CJ, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, et al. IC-P-179: TAU Imaging Relationships With Amyloid B Imaging, CSF TAU/AB42 , and Cognition in Alzheimer’s Disease Alzheimer's & Dementia. 12: P130-P131. DOI: 10.1016/J.Jalz.2016.06.210  0.373
2016 Wang Q, Wang Y, Shimony JS, Owen CJ, Liu J, Fagan AM, Cairns NJ, Ances B, Morris JC, Benzinger TLS. Simultaneous Quantification Of White Matter Abnormalities And Vasogenic Edema In Early Alzheimer Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.203  0.42
2016 Wang Q, Wang Y, Christensen J, Liu J, Fagan AM, Cairns NJ, Ances B, Morris JC, Benzinger TLS. Imaging Marker Of Neuroinflammation Predicts Disease Progression In Alzheimer Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.200  0.398
2016 Kim S, Nho K, Shen L, Franklin EE, Morris JC, Cairns NJ, Saykin AJ. Influence Of Parkinson’S Disease Candidate Genes On Lewy Body Pathology In Autopsy-Confirmed Alzheimer'S Disease Cases Alzheimers & Dementia. 12: 854. DOI: 10.1016/J.Jalz.2016.06.1748  0.446
2016 Wang Q, Wang Y, Shimony JS, Liu J, Fagan AM, Cairns NJ, Ances B, Morris JC, Benzinger TL. White Matter Neuroinflammation In Preclinical Alzheimer Disease Can Be Quantified By Diffusion Basis Spectrum Imaging Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1025  0.36
2016 Gordon BA, Friedrichsen KA, Brier MR, Blazey T, Su Y, Christensen J, McConathy J, Aldea P, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances B, Benzinger TL. P1-263: Relating PET and CSF Measure of TAU Pathology Alzheimer's & Dementia. 12: P513-P514. DOI: 10.1016/J.Jalz.2016.06.1012  0.327
2016 Mishra S, Gordon BA, Friedrichsen KA, Su Y, Christensen J, Aldea P, Cairns NJ, Morris JC, Ances B, Benzinger TL. IC-01-03: Classifying TAU Pet Positivity With [18F]-AV-1451 in Preclinical Alzheimer's Disease Alzheimer's & Dementia. 12: P2-P3. DOI: 10.1016/J.Jalz.2016.06.063  0.381
2015 McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Dirk Keene C, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, et al. The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Acta Neuropathologica. PMID 26667418 DOI: 10.1007/S00401-015-1515-Z  0.451
2015 Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/S00401-015-1509-X  0.397
2015 Guerreiro R, Escott-Price V, Darwent L, Parkkinen L, Ansorge O, Hernandez DG, Nalls MA, Clark L, Honig L, Marder K, van der Flier W, Holstege H, Louwersheimer E, Lemstra A, Scheltens P, ... ... Cairns NJ, et al. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiology of Aging. PMID 26643944 DOI: 10.1016/J.Neurobiolaging.2015.10.028  0.424
2015 Benitez BA, Cairns NJ, Schmidt RE, Morris JC, Norton JB, Cruchaga C, Sands MS. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathologica Communications. 3: 73. PMID 26610600 DOI: 10.1186/S40478-015-0256-5  0.406
2015 Buddhala C, Loftin SK, Kuley BM, Cairns NJ, Campbell MC, Perlmutter JS, Kotzbauer PT. Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease. Annals of Clinical and Translational Neurology. 2: 949-59. PMID 26478895 DOI: 10.1002/Acn3.246  0.313
2015 Hassenstab J, Monsell SE, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W. Neuropsychological Markers of Cognitive Decline in Persons With Alzheimer Disease Neuropathology. Journal of Neuropathology and Experimental Neurology. 74: 1086-92. PMID 26469250 DOI: 10.1097/Nen.0000000000000254  0.384
2015 Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492  0.448
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903  0.372
2015 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Cedarbaum J, Donohue MC, Green RC, Harvey D, Jack CR, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw L, et al. Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 865-84. PMID 26194320 DOI: 10.1016/J.Jalz.2015.04.005  0.474
2015 Franklin EE, Perrin RJ, Vincent B, Baxter M, Morris JC, Cairns NJ. Brain collection, standardized neuropathologic assessment, and comorbidity in Alzheimer's Disease Neuroimaging Initiative 2 participants. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 815-22. PMID 26194314 DOI: 10.1016/J.Jalz.2015.05.010  0.459
2015 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Cedarbaum J, Green RC, Harvey D, Jack CR, Jagust W, Luthman J, Morris JC, Petersen RC, Saykin AJ, Shaw L, et al. 2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: e1-e120. PMID 26073027 DOI: 10.1016/J.Jalz.2014.11.001  0.464
2015 Chung EJ, Babulal GM, Monsell SE, Cairns NJ, Roe CM, Morris JC. Clinical Features of Alzheimer Disease With and Without Lewy Bodies. Jama Neurology. PMID 25985321 DOI: 10.1016/J.Jalz.2015.06.406  0.354
2015 Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC, et al. Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 25964057 DOI: 10.1111/Neup.12205  0.361
2015 Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/S00401-015-1407-2  0.478
2015 Irwin DJ, Cairns NJ, Grossman M, McMillan CT, Lee EB, Van Deerlin VM, Lee VM, Trojanowski JQ. Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine. Acta Neuropathologica. 129: 469-91. PMID 25549971 DOI: 10.1007/S00401-014-1380-1  0.409
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Cairns NJ, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.447
2015 Shim YS, Yang DW, Roe CM, Coats MA, Benzinger TL, Xiong C, Galvin JE, Cairns NJ, Morris JC. Pathological correlates of white matter hyperintensities on magnetic resonance imaging. Dementia and Geriatric Cognitive Disorders. 39: 92-104. PMID 25401390 DOI: 10.1159/000366411  0.413
2015 Russ J, Liu EY, Wu K, Neal D, Suh E, Irwin DJ, McMillan CT, Harms MB, Cairns NJ, Wood EM, Xie SX, Elman L, McCluskey L, Grossman M, Van Deerlin VM, et al. Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier. Acta Neuropathologica. 129: 39-52. PMID 25388784 DOI: 10.1007/S00401-014-1365-0  0.355
2015 Hurth K, Tarawneh R, Ghoshal N, Benzinger TL, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ. Whipple's disease masquerades as dementia with Lewy bodies. Alzheimer Disease and Associated Disorders. 29: 85-9. PMID 23995819 DOI: 10.1097/Wad.0B013E3182A715Da  0.397
2015 Cairns NJ, Perrin RJ, Franklin EE, Vincent B, Carter D, Morris JC. O4-02-01: Age-related neuropathology helps distinguish autosomal dominant from late-onset Alzheimer disease Alzheimer's & Dementia. 11: P269-P269. DOI: 10.1016/J.Jalz.2015.07.351  0.389
2015 Monsell SE, Hassenstab J, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W. Neuropsychological markers of cognitive decline in persons with Alzheimer’s disease neuropathology Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.291  0.325
2015 Day GS, Lim TS, Hassenstab J, Grant EA, Goate A, Morris JC, Cairns NJ. Differentiating corticobasal degeneration and Alzheimer disease by longitudinal clinical and cognitive features Alzheimers & Dementia. 11: 525. DOI: 10.1016/J.Jalz.2015.06.646  0.39
2015 Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Morris JC, Goate A, Kukull W. Genetic differences between symptomatic and asymptomatic persons with Alzheimer's disease neuropathologic change Alzheimers & Dementia. 11: 767. DOI: 10.1016/J.Jalz.2015.06.1711  0.406
2015 Wang Q, Wang Y, Shimony JS, Fagan AM, Cairns NJ, Ances B, Morris JC, Benzinger TLS. Diffusion tensor imaging detected neurodegeneration in preclinical Alzheimer disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.1525  0.368
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.479
2014 Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI. Proteopathic tau seeding predicts tauopathy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: E4376-85. PMID 25261551 DOI: 10.1073/Pnas.1411649111  0.42
2014 Ringman JM, Goate A, Masters CL, Cairns NJ, Danek A, Graff-Radford N, Ghetti B, Morris JC. Genetic heterogeneity in Alzheimer disease and implications for treatment strategies. Current Neurology and Neuroscience Reports. 14: 499. PMID 25217249 DOI: 10.1007/S11910-014-0499-8  0.426
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Cairns NJ, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.373
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, ... ... Cairns NJ, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/Jamaneurol.2014.1654  0.451
2014 Sundaram GS, Garai K, Rath NP, Yan P, Cirrito JR, Cairns NJ, Lee JM, Sharma V. Characterization of a brain permeant fluorescent molecule and visualization of Aβ parenchymal plaques, using real-time multiphoton imaging in transgenic mice. Organic Letters. 16: 3640-3. PMID 25003699 DOI: 10.1021/Ol501264Q  0.394
2014 Bras J, Guerreiro R, Darwent L, Parkkinen L, Ansorge O, Escott-Price V, Hernandez DG, Nalls MA, Clark LN, Honig LS, Marder K, Van Der Flier WM, Lemstra A, Scheltens P, Rogaeva E, ... ... Cairns N, et al. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human Molecular Genetics. 23: 6139-46. PMID 24973356 DOI: 10.1093/Hmg/Ddu334  0.428
2014 Monsell SE, Mock C, Hassenstab J, Roe CM, Cairns NJ, Morris JC, Kukull W. Neuropsychological changes in asymptomatic persons with Alzheimer disease neuropathology. Neurology. 83: 434-40. PMID 24951474 DOI: 10.1212/Wnl.0000000000000650  0.435
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, ... ... Cairns NJ, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  0.341
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, ... ... Cairns NJ, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901  0.489
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Cairns NJ, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.345
2014 Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, ... ... Cairns N, et al. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 505: 550-4. PMID 24336208 DOI: 10.1038/Nature12825  0.41
2014 Cairns N, Perrin RJ, Householder E, Carter D, Vincent B, Morris J. P1-318: NEUROPATHOLOGIC HETEROGENEITY IN ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE (ADNI) SUBJECTS Alzheimer's & Dementia. 10: P428-P428. DOI: 10.1016/J.Jalz.2014.05.559  0.431
2014 Ghetti BF, Newell KL, Abrahamson EE, Cairns NJ, Murrell JR, Oblak AL, Unverzagt FW, Farlow MR, Epperson F, Richardson R, Dupree B, Morris JC, Klunk WE, Saykin AJ, Risacher SL, et al. IC-P-032: COMPARATIVE ANALYSIS OF PIB IN VIVO WITH 6-CN-PIB AND Aβ-IMMUNOHISTOCHEMISTRY POSTMORTEM IN FAMILIAL ALZHEIMER DISEASE ASSOCIATED WITH THE PSEN1 I229F MUTATION Alzheimer's & Dementia. 10: P20-P21. DOI: 10.1016/J.Jalz.2014.05.036  0.421
2013 Toledo JB, Cairns NJ, Da X, Chen K, Carter D, Fleisher A, Householder E, Ayutyanont N, Roontiva A, Bauer RJ, Eisen P, Shaw LM, Davatzikos C, Weiner MW, Reiman EM, et al. Clinical and multimodal biomarker correlates of ADNI neuropathological findings. Acta Neuropathologica Communications. 1: 65. PMID 24252435 DOI: 10.1186/2051-5960-1-65  0.48
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110  0.396
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... ... Cairns NJ, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/Wnl.0B013E3182A841C6  0.433
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/J.Neurol.2013.07.017  0.338
2013 Vos SJ, Xiong C, Visser PJ, Jasielec MS, Hassenstab J, Grant EA, Cairns NJ, Morris JC, Holtzman DM, Fagan AM. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. The Lancet. Neurology. 12: 957-65. PMID 24012374 DOI: 10.1016/S1474-4422(13)70194-7  0.454
2013 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Liu E, Morris JC, Petersen RC, Saykin AJ, Schmidt ME, Shaw L, et al. The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: e111-94. PMID 23932184 DOI: 10.1016/j.jalz.2013.05.1769  0.356
2013 Cheng H, Wang M, Li JL, Cairns NJ, Han X. Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis. Journal of Neurochemistry. 127: 733-8. PMID 23865640 DOI: 10.1111/Jnc.12368  0.441
2013 Campbell MC, Markham J, Flores H, Hartlein JM, Goate AM, Cairns NJ, Videen TO, Perlmutter JS. Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases. Neurology. 81: 520-7. PMID 23825179 DOI: 10.1212/Wnl.0B013E31829E6F94  0.368
2013 Klingstedt T, Shirani H, Ã…slund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP. The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 10179-92. PMID 23780508 DOI: 10.1002/Chem.201301463  0.34
2013 Monsell SE, Mock C, Roe CM, Ghoshal N, Morris JC, Cairns NJ, Kukull W. Comparison of symptomatic and asymptomatic persons with Alzheimer disease neuropathology. Neurology. 80: 2121-9. PMID 23645594 DOI: 10.1212/Wnl.0B013E318295D7A1  0.463
2013 Harms M, Benitez BA, Cairns N, Cooper B, Cooper P, Mayo K, Carrell D, Faber K, Williamson J, Bird T, Diaz-Arrastia R, Foroud TM, Boeve BF, Graff-Radford NR, Mayeux R, et al. C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease. Jama Neurology. 70: 736-41. PMID 23588422 DOI: 10.1001/2013.Jamaneurol.537  0.456
2013 Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL. Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls. Annals of Neurology. 73: 104-19. PMID 23225543 DOI: 10.1002/Ana.23748  0.426
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003  0.368
2013 Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002  0.39
2013 Armstrong RA, Hamilton RL, Mackenzie IR, Hedreen J, Cairns NJ. Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting. Neuropathology and Applied Neurobiology. 39: 335-47. PMID 22804696 DOI: 10.1111/J.1365-2990.2012.01291.X  0.381
2013 Armstrong RA, Cairns NJ. Spatial patterns of the tau pathology in progressive supranuclear palsy. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 34: 337-44. PMID 22411688 DOI: 10.1007/S10072-012-1006-0  0.357
2013 Mills S, Mallmann J, Santacruz A, Fuqua A, Carril M, Aisen P, Althage M, Belyew S, Benzinger T, Brooks W, Buckles V, Cairns N, Clifford D, Danek A, Fagan A, et al. Erratum to “Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial” [Rev. Neurol. 169 (10) (2013) 737–743] Revue Neurologique. 169: 1018. DOI: 10.1016/J.Neurol.2013.10.005  0.332
2013 Chasse R, Benzinger T, Grant E, Cairns N, Fagan A, Morris J, Hassenstab J. Alzheimer's disease biomarkers and normative cognitive data: The SuperNorms approach Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.08.220  0.389
2013 Thomas J, Brier M, Bateman R, Snyder A, Benzinger T, Xiong C, Raichle M, Sperling R, Mayeux R, Ghetti B, Ringman J, Salloway S, McDade E, Rossor M, Schofield P, ... ... Cairns N, et al. IC-P-184: Resting state functional connectivity in autosomal dominant and sporadic Alzheimer's disease Alzheimer's & Dementia. 9: P105-P105. DOI: 10.1016/J.Jalz.2013.05.181  0.377
2013 Gitcho M, Joshi G, Cairns N, Johnson J. Age-dependent accumulation of phosphorylated TDP-43 in an Alzheimer's disease mouse model Alzheimers & Dementia. 9: 721. DOI: 10.1016/J.Jalz.2013.05.1440  0.404
2013 Blazey T, Jack C, Kantarci K, Preboske G, Ringman J, Brickman A, Raichle M, Hornbeck R, Saykin A, Salloway S, McDade E, Rossor M, Fox N, Thompson P, Correia S, ... ... Cairns N, et al. Prevalence and growth of cerebral microhemorrhages in autosomal dominant Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.100  0.408
2013 Vos S, Xiong C, Grant E, Visser PJ, Cairns N, Morris J, Holtzman D, Fagan A. O4-02-03: Using cerebrospinal fluid markers to identify stages of National Institute on Aging and Alzheimer's Association proposed criteria for preclinical Alzheimer's disease and its prognosis Alzheimer's & Dementia. 9: P682-P682. DOI: 10.1016/J.Jalz.2013.04.342  0.397
2013 Kinnunen K, Ryan N, Cash D, Leite AB, Finnegan S, Cardoso M, Leung K, Modat M, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Ringman J, Ghetti B, ... ... Cairns N, et al. Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent? Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.017  0.403
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93  0.318
2012 Halliday G, Bigio EH, Cairns NJ, Neumann M, Mackenzie IR, Mann DM. Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects. Acta Neuropathologica. 124: 373-82. PMID 22878865 DOI: 10.1007/S00401-012-1030-4  0.388
2012 Kotzbauer PT, Cairns NJ, Campbell MC, Willis AW, Racette BA, Tabbal SD, Perlmutter JS. Pathologic accumulation of α-synuclein and Aβ in Parkinson disease patients with dementia. Archives of Neurology. 69: 1326-31. PMID 22825369 DOI: 10.1001/Archneurol.2012.1608  0.381
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753  0.438
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7  0.443
2012 McDonald JM, Cairns NJ, Taylor-Reinwald L, Holtzman D, Walsh DM. The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain. Brain Research. 1450: 138-47. PMID 22440675 DOI: 10.1016/J.Brainres.2012.02.041  0.411
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/J.Jalz.2011.10.007  0.498
2012 Rademakers R, Baker M, Nicholson AM, Rutherford NJ, Finch N, Soto-Ortolaza A, Lash J, Wider C, Wojtas A, DeJesus-Hernandez M, Adamson J, Kouri N, Sundal C, Shuster EA, Aasly J, ... ... Cairns NJ, et al. Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids. Nature Genetics. 44: 200-5. PMID 22197934 DOI: 10.1038/Ng.1027  0.308
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/S00401-011-0910-3  0.485
2012 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Liu E, Morris JC, Petersen RC, Saykin AJ, Schmidt ME, Shaw L, et al. The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: S1-68. PMID 22047634 DOI: 10.1016/J.Jalz.2011.09.172  0.461
2012 Ghoshal N, Dearborn JT, Wozniak DF, Cairns NJ. Core features of frontotemporal dementia recapitulated in progranulin knockout mice. Neurobiology of Disease. 45: 395-408. PMID 21933710 DOI: 10.1016/J.Nbd.2011.08.029  0.319
2012 Armstrong RA, Carter D, Cairns NJ. A quantitative study of the neuropathology of 32 sporadic and familial cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP). Neuropathology and Applied Neurobiology. 38: 25-38. PMID 21696412 DOI: 10.1111/J.1365-2990.2011.01188.X  0.334
2012 Brody D, Esparza T, Zhao H, Cirrito J, Cairns N, Bateman R, Holtzman D. P4-266: BETA-AMYLOID oligomerization in Alzheimer's DISEASE DEMENTIA versus high pathology controls Alzheimer's & Dementia. 8: S752-S752. DOI: 10.1016/J.Jalz.2013.08.047  0.444
2012 Becker J, Koeppe R, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, Brickman A, Ghetti B, Masters C, ... ... Cairns N, et al. FDG metabolism in the DIAN study of autosomal dominant Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.655  0.405
2012 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, ... ... Cairns N, et al. O2-06-01: Disrupted functional connectivity in autosomal dominant Alzheimer's disease: Preliminary findings from the DIAN study Alzheimer's & Dementia. 8: P244-P245. DOI: 10.1016/J.Jalz.2012.05.654  0.391
2012 Benzinger T, Blazey T, Ances B, Raichle M, Ances B, Snyder A, Su Y, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Cairns N, et al. IC-P-128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study Alzheimer's & Dementia. 8: P68-P69. DOI: 10.1016/j.jalz.2012.05.1858  0.406
2012 Benzinger T, Blazey T, Koeppe R, Jack C, Raichle M, Su Y, Snyder A, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Cairns N, et al. Elevated PiB precedes dementia in autosomal dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.132  0.479
2012 Cash D, Ridgway G, Ryan N, Kinnunen K, Yeatman T, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, Salloway S, ... ... Cairns N, et al. A voxel-based morphometry study of volumetric MRI in familial Alzheimer’s disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.052  0.37
2012 Bateman R, Benzinger T, Cairns N, Fagan A, Goate A, Marcus D, Storandt M, Xiong C, Buckles V, Holtzman D, Moulder K, Oliver A, Santacruz A, Fox N, Ghetti B, et al. Presymptomatic Alzheimer's disease in the Dominantly Inherited Alzheimer's Network (DIAN) Alzheimers & Dementia. 8: 4. DOI: 10.1016/J.Jalz.2012.05.015  0.425
2011 Zhu L, Cairns NJ, Tabbal SD, Racette BA. Pregnancy in multiple system atrophy: a case report. Journal of Medical Case Reports. 5: 599. PMID 22208291 DOI: 10.1186/1752-1947-5-599  0.36
2011 Tarawneh R, D'Angelo G, Macy E, Xiong C, Carter D, Cairns NJ, Fagan AM, Head D, Mintun MA, Ladenson JH, Lee JM, Morris JC, Holtzman DM. Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease. Annals of Neurology. 70: 274-85. PMID 21823155 DOI: 10.1002/Ana.22448  0.443
2011 Armstrong RA, Cairns NJ. Spatial patterns of TDP-43 neuronal cytoplasmic inclusions (NCI) in fifteen cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP). Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 32: 653-9. PMID 21647631 DOI: 10.1007/S10072-011-0639-8  0.36
2011 Page T, Gitcho MA, Mosaheb S, Carter D, Chakraverty S, Perry RH, Bigio EH, Gearing M, Ferrer I, Goate AM, Cairns NJ, Thorpe JR. FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience : Mn. 45: 409-21. PMID 21603978 DOI: 10.1007/S12031-011-9549-8  0.35
2011 Mackenzie IR, Neumann M, Cairns NJ, Munoz DG, Isaacs AM. Novel types of frontotemporal lobar degeneration: beyond tau and TDP-43. Journal of Molecular Neuroscience : Mn. 45: 402-8. PMID 21603977 DOI: 10.1007/S12031-011-9551-1  0.324
2011 Armstrong RA, Cairns NJ. A morphometric study of the spatial patterns of TDP-43 immunoreactive neuronal inclusions in frontotemporal lobar degeneration (FTLD) with progranulin (GRN) mutation. Histology and Histopathology. 26: 185-90. PMID 21154232 DOI: 10.14670/Hh-26.185  0.303
2011 Mackenzie IR, Munoz DG, Kusaka H, Yokota O, Ishihara K, Roeber S, Kretzschmar HA, Cairns NJ, Neumann M. Distinct pathological subtypes of FTLD-FUS. Acta Neuropathologica. 121: 207-18. PMID 21052700 DOI: 10.1007/S00401-010-0764-0  0.396
2011 Dequen F, Cairns NJ, Bigio EH, Julien JP. Gigaxonin mutation analysis in patients with NIFID. Neurobiology of Aging. 32: 1528-9. PMID 19782434 DOI: 10.1016/J.Neurobiolaging.2009.08.018  0.386
2011 Taylor-Reinwald L, Grant E, Goate A, Morris J, Cairns N. Neuropathology of preclinical and incipient Alzheimer's dementia Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.881  0.441
2010 Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, et al. YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biological Psychiatry. 68: 903-12. PMID 21035623 DOI: 10.1016/J.Biopsych.2010.08.025  0.465
2010 Foster ER, Campbell MC, Burack MA, Hartlein J, Flores HP, Cairns NJ, Hershey T, Perlmutter JS. Amyloid imaging of Lewy body-associated disorders. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 2516-23. PMID 20922808 DOI: 10.1002/Mds.23393  0.386
2010 Cairns NJ, Perrin RJ, Schmidt RE, Gru A, Green KG, Carter D, Taylor-Reinwald L, Morris JC, Gitcho MA, Baloh RH. TDP-43 proteinopathy in familial motor neurone disease with TARDBP A315T mutation: a case report. Neuropathology and Applied Neurobiology. 36: 673-9. PMID 20819167 DOI: 10.1111/J.1365-2990.2010.01121.X  0.344
2010 Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, et al. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Annals of Neurology. 68: 162-72. PMID 20695009 DOI: 10.1002/Ana.22094  0.367
2010 Cairns NJ, Taylor-Reinwald L, Morris JC. Autopsy consent, brain collection, and standardized neuropathologic assessment of ADNI participants: the essential role of the neuropathology core. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 274-9. PMID 20451876 DOI: 10.1016/J.Jalz.2010.03.012  0.369
2010 Weiner MW, Aisen PS, Jack CR, Jagust WJ, Trojanowski JQ, Shaw L, Saykin AJ, Morris JC, Cairns N, Beckett LA, Toga A, Green R, Walter S, Soares H, Snyder P, et al. The Alzheimer's disease neuroimaging initiative: progress report and future plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 202-11.e7. PMID 20451868 DOI: 10.1016/J.Jalz.2010.03.007  0.431
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Cairns NJ, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.306
2010 Armstrong RA, Cairns NJ. Analysis of beta-amyloid (Abeta) deposition in the temporal lobe in Alzheimer's disease using Fourier (spectral) analysis. Neuropathology and Applied Neurobiology. 36: 248-57. PMID 20132489 DOI: 10.1111/J.1365-2990.2010.01071.X  0.399
2010 Burack MA, Hartlein J, Flores HP, Taylor-Reinwald L, Perlmutter JS, Cairns NJ. In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia. Neurology. 74: 77-84. PMID 20038776 DOI: 10.1212/Wnl.0B013E3181C7Da8E  0.464
2010 Armstrong RA, Ellis W, Hamilton RL, Mackenzie IR, Hedreen J, Gearing M, Montine T, Vonsattel JP, Head E, Lieberman AP, Cairns NJ. Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 227-39. PMID 20012109 DOI: 10.1007/S00702-009-0350-6  0.38
2010 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica. 119: 1-4. PMID 19924424 DOI: 10.1007/S00401-009-0612-2  0.326
2010 Tarawneh R, Ohlendorf MF, Macy EM, McQuillan J, Head D, Cairns NJ, Fagan AM, Mintun MA, Ladenson JH, Lee J, Morris JC, Holtzman DM. P4-060: The Novel Neuronal Injury Marker, Visinin-like Protein-1 (VILIP-1), as a Diagnostic and Prognostic Marker in Alzheimer's Disease Alzheimer's & Dementia. 6: e38-e39. DOI: 10.1016/J.Jalz.2010.08.120  0.378
2010 Craig-Schapiro R, Perrin RJ, Roe CM, Grant EA, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, et al. P3-190: A novel diagnostic and prognostic fluid biomarker for early Alzheimer's disease: YKL-40 Alzheimer's & Dementia. 6: S506-S506. DOI: 10.1016/J.Jalz.2010.05.1688  0.393
2009 Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah AR, Reinwald LT, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report. Archives of Neurology. 66: 1557-62. PMID 20008664 DOI: 10.1001/Archneurol.2009.279  0.435
2009 Wegorzewska I, Bell S, Cairns NJ, Miller TM, Baloh RH. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proceedings of the National Academy of Sciences of the United States of America. 106: 18809-14. PMID 19833869 DOI: 10.1073/Pnas.0908767106  0.348
2009 Armstrong RA, Cairns NJ. Size frequency distribution of the beta-amyloid (abeta) deposits in dementia with Lewy bodies with associated Alzheimer's disease pathology. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 30: 471-7. PMID 19768369 DOI: 10.1007/S10072-009-0135-6  0.412
2009 Norton JB, Cairns NJ, Chakraverty S, Wang J, Levitch D, Galvin JE, Goate A. Presenilin1 G217R mutation linked to Alzheimer disease with cotton wool plaques. Neurology. 73: 480-2. PMID 19667325 DOI: 10.1212/Wnl.0B013E3181B163Ba  0.379
2009 Gitcho MA, Bigio EH, Mishra M, Johnson N, Weintraub S, Mesulam M, Rademakers R, Chakraverty S, Cruchaga C, Morris JC, Goate AM, Cairns NJ. TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy. Acta Neuropathologica. 118: 633-45. PMID 19618195 DOI: 10.1007/S00401-009-0571-7  0.34
2009 Gitcho MA, Strider J, Carter D, Taylor-Reinwald L, Forman MS, Goate AM, Cairns NJ. VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death. The Journal of Biological Chemistry. 284: 12384-98. PMID 19237541 DOI: 10.1074/Jbc.M900992200  0.357
2009 Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, Traynor BJ, Ruano D, Cairns N, Rohrer JD, Mead S, Collinge J, Rossor M, Akay E, Guerreiro R, et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiology of Aging. 30: 656-65. PMID 19217189 DOI: 10.1016/J.Neurobiolaging.2009.01.009  0.345
2009 Armstrong RA, Ironside JW, Lantos PL, Cairns NJ. A quantitative study of the pathological changes in the cerebellum in 15 cases of variant Creutzfeldt-Jakob disease (vCJD). Neuropathology and Applied Neurobiology. 35: 36-45. PMID 19187059 DOI: 10.1111/J.1365-2990.2008.00979.X  0.356
2009 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathologica. 117: 15-8. PMID 19015862 DOI: 10.1007/S00401-008-0460-5  0.335
2009 Liščić RM, Behrens MI, Morris JC, Cairns NJ. HDDD with Alzheimer's disease as common comorbidity: A clinicopathologic case report Journal of the Neurological Sciences. 283: 256-257. DOI: 10.1016/J.Jns.2009.02.071  0.474
2008 Thorpe JR, Tang H, Atherton J, Cairns NJ. Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy. Journal of Neural Transmission (Vienna, Austria : 1996). 115: 1661-71. PMID 18974920 DOI: 10.1007/S00702-008-0137-1  0.36
2008 Liscic RM, Grinberg LT, Zidar J, Gitcho MA, Cairns NJ. ALS and FTLD: two faces of TDP-43 proteinopathy. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 15: 772-80. PMID 18684309 DOI: 10.1111/J.1468-1331.2008.02195.X  0.335
2008 Roe CM, Xiong C, Miller JP, Cairns NJ, Morris JC. Interaction of neuritic plaques and education predicts dementia. Alzheimer Disease and Associated Disorders. 22: 188-93. PMID 18525294 DOI: 10.1097/Wad.0B013E3181610Fff  0.384
2008 Armstrong RA, Lantos PL, Cairns NJ. What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease? Neuropathology : Official Journal of the Japanese Society of Neuropathology. 28: 351-65. PMID 18433435 DOI: 10.1111/J.1440-1789.2008.00916.X  0.425
2008 Hatanpaa KJ, Bigio EH, Cairns NJ, Womack KB, Weintraub S, Morris JC, Foong C, Xiao G, Hladik C, Mantanona TY, White CL. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of Neuropathology and Experimental Neurology. 67: 271-9. PMID 18379440 DOI: 10.1097/Nen.0B013E31816A12A6  0.413
2008 Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, ... ... Cairns NJ, et al. TDP-43 A315T mutation in familial motor neuron disease. Annals of Neurology. 63: 535-8. PMID 18288693 DOI: 10.1002/Ana.21344  0.349
2008 Mukherjee O, Wang J, Gitcho M, Chakraverty S, Taylor-Reinwald L, Shears S, Kauwe JS, Norton J, Levitch D, Bigio EH, Hatanpaa KJ, White CL, Morris JC, Cairns NJ, Goate A. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia. Human Mutation. 29: 512-21. PMID 18183624 DOI: 10.1002/Humu.20681  0.402
2008 Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, et al. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Human Molecular Genetics. 17: 759-67. PMID 18063669 DOI: 10.1093/Hmg/Ddm348  0.378
2008 Wippold FJ, Cairns N, Vo K, Holtzman DM, Morris JC. Neuropathology for the neuroradiologist: plaques and tangles. Ajnr. American Journal of Neuroradiology. 29: 18-22. PMID 17925367 DOI: 10.3174/Ajnr.A0781  0.482
2008 Taylor-Reinwald L, Carter D, Felton A, Grant E, Morris JC, Cairns NJ. P4-159: Postmortem neuropathologic assessment of Aβ-deposition in the precuneus of cognitively normal individuals Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2226  0.335
2008 Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CH, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, ... ... Cairns NJ, et al. P3-287: TDP-43 A315T mutation in familial motor neuron disease Alzheimer's & Dementia. 4: T606-T607. DOI: 10.1016/J.Jalz.2008.05.1855  0.322
2007 Hu Y, Hosseini A, Kauwe JS, Gross J, Cairns NJ, Goate AM, Fagan AM, Townsend RR, Holtzman DM. Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease. Proteomics. Clinical Applications. 1: 1373-84. PMID 21136637 DOI: 10.1002/Prca.200600999  0.435
2007 Armstrong RA, Lantos PL, Cairns NJ. Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 1569-77. PMID 17680229 DOI: 10.1007/S00702-007-0796-3  0.364
2007 Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. The American Journal of Pathology. 171: 227-40. PMID 17591968 DOI: 10.2353/Ajpath.2007.070182  0.377
2007 Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathologica. 114: 5-22. PMID 17579875 DOI: 10.1007/S00401-007-0237-2  0.438
2007 Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/Ana.21147  0.309
2007 Liscic RM, Storandt M, Cairns NJ, Morris JC. Clinical and psychometric distinction of frontotemporal and Alzheimer dementias. Archives of Neurology. 64: 535-40. PMID 17420315 DOI: 10.1001/Archneur.64.4.535  0.451
2007 Behrens MI, Mukherjee O, Tu PH, Liscic RM, Grinberg LT, Carter D, Paulsmeyer K, Taylor-Reinwald L, Gitcho M, Norton JB, Chakraverty S, Goate AM, Morris JC, Cairns NJ. Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation. Alzheimer Disease and Associated Disorders. 21: 1-7. PMID 17334266 DOI: 10.1097/Wad.0B013E31803083F2  0.453
2007 Neumann M, Mackenzie IR, Cairns NJ, Boyer PJ, Markesbery WR, Smith CD, Taylor JP, Kretzschmar HA, Kimonis VE, Forman MS. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. Journal of Neuropathology and Experimental Neurology. 66: 152-7. PMID 17279000 DOI: 10.1096/Fasebj.21.5.A25  0.415
2007 Armstrong RA, Cairns NJ. Spatial patterns of the pathological changes in neuronal intermediate filament inclusion disease (NIFID): an alpha-internexin immunohistochemical study. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 451-6. PMID 17109074 DOI: 10.1007/S00702-006-0595-2  0.32
2007 Armstrong RA, Lantos PL, Cairns NJ. Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy. Parkinsonism & Related Disorders. 13: 50-4. PMID 17046313 DOI: 10.1016/J.Parkreldis.2006.07.004  0.309
2007 Hatanpaa KJ, Bigio EH, Cairns NJ, Schneider JA, Foong C, Hladik C, Shang P, White CL. TDP-43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a Midwest-Southwest Consortium for FTLD study Journal of Neuropathology and Experimental Neurology. 66: 425. DOI: 10.1096/Fasebj.21.5.A24-C  0.361
2006 Mukherjee O, Pastor P, Cairns NJ, Chakraverty S, Kauwe JS, Shears S, Behrens MI, Budde J, Hinrichs AL, Norton J, Levitch D, Taylor-Reinwald L, Gitcho M, Tu PH, Tenenholz Grinberg L, et al. HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin. Annals of Neurology. 60: 314-22. PMID 16983685 DOI: 10.1002/Ana.20963  0.376
2006 Armstrong RA, Cairns NJ, Ironside JW. Size frequency distributions of the florid prion protein aggregates in variant Creutzfeldt-Jakob disease follow a power-law function. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 27: 104-9. PMID 16816906 DOI: 10.1007/S10072-006-0608-9  0.317
2006 Forman MS, Mackenzie IR, Cairns NJ, Swanson E, Boyer PJ, Drachman DA, Jhaveri BS, Karlawish JH, Pestronk A, Smith TW, Tu PH, Watts GD, Markesbery WR, Smith CD, Kimonis VE. Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations. Journal of Neuropathology and Experimental Neurology. 65: 571-81. PMID 16783167 DOI: 10.1097/00005072-200606000-00005  0.388
2006 Armstrong RA, Cairns NJ, Lantos PL. Multiple system atrophy (MSA): topographic distribution of the alpha-synuclein-associated pathological changes. Parkinsonism & Related Disorders. 12: 356-62. PMID 16723266 DOI: 10.1016/J.Parkreldis.2006.02.005  0.305
2006 Armstrong RA, Cairns NJ. Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 13: 528-32. PMID 16722980 DOI: 10.1111/J.1468-1331.2006.01284.X  0.342
2006 Hashemzadeh-Bonehi L, Phillips RG, Cairns NJ, Mosaheb S, Thorpe JR. Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration. Experimental Neurology. 199: 328-38. PMID 16480979 DOI: 10.1016/J.Expneurol.2005.12.030  0.432
2006 Armstrong RA, Kerty E, Skullerud K, Cairns NJ. Neuropathological changes in ten cases of neuronal intermediate filament inclusion disease (NIFID): a study using alpha-internexin immunohistochemistry and principal components analysis (PCA). Journal of Neural Transmission (Vienna, Austria : 1996). 113: 1207-15. PMID 16362634 DOI: 10.1007/S00702-005-0387-0  0.305
2006 Momeni P, Cairns NJ, Perry RH, Bigio EH, Gearing M, Singleton AB, Hardy J. Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID). Neurobiology of Aging. 27: 778.e1-778.e6. PMID 16005115 DOI: 10.1016/J.Neurobiolaging.2005.03.030  0.423
2006 Sinha N, Zhou A, Xiong C, Morris JC, Bateman RJ, Benzinger TL, Cairns NJ. P2-436: PIB-PET NEUROIMAGING CORRELATES WITH β-AMYLOIDOSIS IN BOTH LATE-ONSET AND AUTOSOMAL DOMINANT ALZHEIMER DISEASE Alzheimer's & Dementia. 14: P881-P881. DOI: 10.1016/J.Jalz.2018.06.1128  0.392
2006 Grinberg LT, Liscic RM, Pang-hsien T, McKeel D, Carter D, Taylor-Reinwald LM, Morris JC, Cairns NJ. P4-117: Extending the neuropathological spectrum of frontotemporal lobar degenerations: A review of 833 prospectively assessed dementia cases Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1856  0.345
2006 Cairns NJ, Tu P, Pastor P, Norton J, Chakraverty S, Mukherjee O, Carter D, Behrens MI, Morris JC, Goate A. P4-108: Hereditary dysphasic disinhibition dementia 2 is a chromosome 17q21-linked frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions Alzheimer's & Dementia. 2: S546-S546. DOI: 10.1016/J.Jalz.2006.05.1847  0.318
2005 Cairns NJ, Armstrong RA. Spatial patterns of the pathological changes in the temporal lobe of patients with neuronal intermediate filament inclusion disease. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 25: 298-303. PMID 16382778 DOI: 10.1111/J.1440-1789.2005.00639.X  0.315
2005 Rezaie P, Pontikis CC, Hudson L, Cairns NJ, Lantos PL. Expression of cellular prion protein in the frontal and occipital lobe in Alzheimer's disease, diffuse Lewy body disease, and in normal brain: an immunohistochemical study. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 929-40. PMID 16055747 DOI: 10.1369/Jhc.4A6551.2005  0.381
2005 Mosaheb S, Thorpe JR, Hashemzadeh-Bonehi L, Bigio EH, Gearing M, Cairns NJ. Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease. Acta Neuropathologica. 110: 360-8. PMID 16025283 DOI: 10.1007/S00401-005-1057-X  0.366
2005 Sudo S, Shiozawa M, Cairns NJ, Wada Y. Aberrant accentuation of neurofibrillary degeneration in the hippocampus of Alzheimer's disease with amyloid precursor protein 717 and presenilin-1 gene mutations. Journal of the Neurological Sciences. 234: 55-65. PMID 15946688 DOI: 10.1016/j.jns.2005.03.043  0.348
2005 Armstrong RA, Cairns NJ, Ironside JW, Lantos PL. Size frequency distribution of prion protein (PrP) aggregates in variant Creutzfeldt-Jakob disease (vCJD). Journal of Neural Transmission (Vienna, Austria : 1996). 112: 1565-73. PMID 15785857 DOI: 10.1007/S00702-005-0296-2  0.361
2005 Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain. Neurobiology of Aging. 26: 795-802. PMID 15718037 DOI: 10.1016/J.Neurobiolaging.2004.07.011  0.355
2004 Cairns NJ, Lee VM, Trojanowski JQ. The cytoskeleton in neurodegenerative diseases. The Journal of Pathology. 204: 438-49. PMID 15495240 DOI: 10.1002/Path.1650  0.336
2004 Schuessel K, Leutner S, Cairns NJ, Müller WE, Eckert A. Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain. Journal of Neural Transmission (Vienna, Austria : 1996). 111: 1167-82. PMID 15338332 DOI: 10.1007/s00702-004-0156-5  0.305
2004 Cairns NJ, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Lee VM, Trojanowski JQ. alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. The American Journal of Pathology. 164: 2153-61. PMID 15161649 DOI: 10.1016/S0002-9440(10)63773-X  0.311
2004 Katzov H, Chalmers K, Palmgren J, Andreasen N, Johansson B, Cairns NJ, Gatz M, Wilcock GK, Love S, Pedersen NL, Brookes AJ, Blennow K, Kehoe PG, Prince JA. Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism. Human Mutation. 23: 358-67. PMID 15024730 DOI: 10.1002/Humu.20012  0.306
2004 Kehoe PG, Katzov H, Andreasen N, Gatz M, Wilcock GK, Cairns NJ, Palmgren J, de Faire U, Brookes AJ, Pedersen NL, Blennow K, Prince JA. Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease. Human Genetics. 114: 478-83. PMID 14986105 DOI: 10.1007/S00439-004-1093-Y  0.319
2004 Momeni P, Cairns N, Perry R, Jaros E, Singleton AB, Hardy J. P4-164 Molecular study of dementia with neurofilament inclusions Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81722-6  0.328
2003 Armstrong RA, Lantos PL, Cairns NJ. A quantitative study of the pathological changes in cortical neurons in sporadic Creutzfeldt-Jakob disease. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 23: 181-7. PMID 14570284 DOI: 10.1046/J.1440-1789.2003.00495.X  0.321
2003 Cairns NJ, Perry RH, Jaros E, Burn D, McKeith IG, Lowe JS, Holton J, Rossor MN, Skullerud K, Duyckaerts C, Cruz-Sanchez FF, Lantos PL. Patients with a novel neurofilamentopathy: dementia with neurofilament inclusions. Neuroscience Letters. 341: 177-80. PMID 12697277 DOI: 10.1016/S0304-3940(03)00100-9  0.35
2003 Kehoe PG, Katzov H, Feuk L, Bennet AM, Johansson B, Wiman B, de Faire U, Cairns NJ, Wilcock GK, Brookes AJ, Blennow K, Prince JA. Haplotypes extending across ACE are associated with Alzheimer's disease. Human Molecular Genetics. 12: 859-67. PMID 12668609 DOI: 10.1093/Hmg/Ddg094  0.383
2002 Cook L, Brayne CE, Easton D, Evans JG, Xuereb J, Cairns NJ, Rubinsztein DC. No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease. Annals of Neurology. 52: 690-1. PMID 12402275 DOI: 10.1002/ana.10362  0.31
2002 Emilsson L, Saetre P, Balciuniene J, Castensson A, Cairns N, Jazin EE. Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimer's disease patients. Neuroscience Letters. 326: 56-60. PMID 12052537 DOI: 10.1016/s0304-3940(02)00307-5  0.321
2002 Lantos PL, Cairns NJ, Khan MN, King A, Revesz T, Janssen JC, Morris H, Rossor MN. Neuropathologic variation in frontotemporal dementia due to the intronic tau 10(+16) mutation. Neurology. 58: 1169-75. PMID 11971082 DOI: 10.1212/Wnl.58.8.1169  0.442
2001 Mann DM, Takeuchi A, Sato S, Cairns NJ, Lantos PL, Rossor MN, Haltia M, Kalimo H, Iwatsubo T. Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques. Neuropathology and Applied Neurobiology. 27: 189-96. PMID 11489138 DOI: 10.1046/J.1365-2990.2001.00316.X  0.401
2001 Ishii K, Lippa C, Tomiyama T, Miyatake F, Ozawa K, Tamaoka A, Hasegawa T, Fraser PE, Shoji S, Nee LE, Pollen DA, St George-Hyslop PH, Ii K, Ohtake T, Kalaria RN, ... ... Cairns NJ, et al. Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition. Neurobiology of Aging. 22: 367-76. PMID 11378241 DOI: 10.1016/S0197-4580(01)00216-0  0.409
2001 Taylor AE, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. Journal of Medical Genetics. 38: 232-3. PMID 11283204 DOI: 10.1136/Jmg.38.4.232  0.442
2001 Yoo BC, Cairns N, Fountoulakis M, Lubec G. Synaptosomal Proteins, Beta-Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein (Beta-SNAP), Gamma-SNAP and Synaptotagmin I in Brain of Patients with Down Syndrome and Alzheimer’s Disease Dementia and Geriatric Cognitive Disorders. 12: 219-225. PMID 11244216 DOI: 10.1159/000051261  0.386
2001 Murphy T, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease. Neuroreport. 12: 631-4. PMID 11234778 DOI: 10.1097/00001756-200103050-00040  0.434
2000 Bell K, Cairns NJ, Lantos PL, Rossor MN. Immunohistochemistry distinguishes: between Pick's disease and corticobasal degeneration. Journal of Neurology, Neurosurgery, and Psychiatry. 69: 835-6. PMID 11185644 DOI: 10.1136/Jnnp.69.6.835  0.484
2000 Morris HR, Vaughan JR, Datta SR, Bandopadhyay R, Rohan De Silva HA, Schrag A, Cairns NJ, Burn D, Nath U, Lantos PL, Daniel S, Lees AJ, Quinn NP, Wood NW. Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE. Neurology. 55: 1918-20. PMID 11134398 DOI: 10.1212/Wnl.55.12.1918  0.313
2000 Pickering-Brown S, Baker M, Yen SH, Liu WK, Hasegawa M, Cairns N, Lantos PL, Rossor M, Iwatsubo T, Davies Y, Allsop D, Furlong R, Owen F, Hardy J, Mann D, et al. Pick's disease is associated with mutations in the tau gene. Annals of Neurology. 48: 859-67. PMID 11117542 DOI: 10.1002/1531-8249(200012)48:6<859::Aid-Ana6>3.0.Co;2-1  0.416
2000 Fukutani Y, Cairns NJ, Shiozawa M, Sasaki K, Sudo S, Isaki K, Lantos PL. Neuronal loss and neurofibrillary degeneration in the hippocampal cortex in late-onset sporadic Alzheimer's disease. Psychiatry and Clinical Neurosciences. 54: 523-9. PMID 11043800 DOI: 10.1046/J.1440-1819.2000.00747.X  0.351
2000 Narain Y, Yip A, Murphy T, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Furlong RA, Rubinsztein DC. The ACE gene and Alzheimer's disease susceptibility. Journal of Medical Genetics. 37: 695-7. PMID 10978362 DOI: 10.1136/Jmg.37.9.695  0.393
2000 Armstrong RA, Cairns NJ, Lantos PL. Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 11: 187-92. PMID 10867443 DOI: 10.1159/000017235  0.452
2000 Eckert GP, Cairns NJ, Maras A, Gattaz WF, Müller WE. Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 11: 181-6. PMID 10867442 DOI: 10.1159/000017234  0.352
2000 Pickering-Brown SM, Owen F, Isaacs A, Snowden J, Varma A, Neary D, Furlong R, Daniel SE, Cairns NJ, Mann DM. Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology. Experimental Neurology. 163: 452-6. PMID 10833320 DOI: 10.1006/Exnr.2000.7387  0.453
2000 Armstrong RA, Cairns NJ, Lantos PL. A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration. Experimental Neurology. 163: 348-56. PMID 10833308 DOI: 10.1006/Exnr.2000.7392  0.366
2000 McAuley DF, Johnston GD, Marra C, Silveri MC, Gainotti G, Ólafsdóttir M, Skoog I, Marcusson J, Armstrong RA, Cairns NJ, Lantos PL, McGleenon BM, Passmore AP, Eckert GP, Maras A, et al. APOE Genotype and Alzheimer´s Disease Dementia and Geriatric Cognitive Disorders. 11: 237-237. DOI: 10.1159/000017243  0.366
2000 Ballard C, Piggott M, Johnson M, Cairns N, Perry R, McKeith I, Jaros E, O'Brien J, Holmes C, Perry E. Delusions associated with elevated muscarinic binding in dementia with Lewy bodies Annals of Neurology. 48: 868-876. DOI: 10.1002/1531-8249(200012)48:6<868::Aid-Ana7>3.0.Co;2-0  0.398
1999 Armstrong R, Cairns N, Lantos P. The spatial patterns of Pick bodies, Pick cells and Alzheimer's disease pathology in Pick's disease. Neuropathology. 19: 64-70. PMID 19519649 DOI: 10.1046/J.1440-1789.1999.00219.X  0.368
1999 Eckert GP, Cairns NJ, Müller WE. Piracetam reverses hippocampal membrane alterations in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 106: 757-61. PMID 10907734 DOI: 10.1007/S007020050196  0.346
1999 Yeghiazaryan K, Turhani-Schatzmann D, Labudova O, Schuller E, Olson EN, Cairns N, Lubec G. Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome. Journal of Neural Transmission. Supplementum. 57: 305-14. PMID 10666685 DOI: 10.1007/978-3-7091-6380-1_21  0.389
1999 Labudova O, Cairns N, Kitzmüller E, Lubec G. Impaired brain glucose metabolism in patients with Down syndrome. Journal of Neural Transmission-Supplement. 57: 247-256. PMID 10666680 DOI: 10.1007/978-3-7091-6380-1_16  0.324
1999 Cairns NJ. Neuropathology. Journal of Neural Transmission. Supplementum. 57: 61-74. PMID 10666668  0.312
1999 Kovács T, Cairns NJ, Lantos PL. Alpha-2-macroglobulin intronic polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease. Neuroscience Letters. 273: 61-83. PMID 10505652 DOI: 10.1016/S0304-3940(99)00604-7  0.417
1999 Armstrong RA, Cairns NJ, Lantos PL. Laminar distribution of pick bodies, pick cells and Alzheimer disease pathology in the frontal and temporal cortex in Pick's disease. Neuropathology and Applied Neurobiology. 25: 266-71. PMID 10476043 DOI: 10.1046/J.1365-2990.1999.00173.X  0.354
1999 Gómez-Isla T, Growdon WB, McNamara MJ, Nochlin D, Bird TD, Arango JC, Lopera F, Kosik KS, Lantos PL, Cairns NJ, Hyman BT. The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors. Brain : a Journal of Neurology. 122: 1709-19. PMID 10468510 DOI: 10.1093/Brain/122.9.1709  0.363
1999 Guan Z, Wang Y, Cairns NJ, Lantos PL, Dallner G, Sindelar PJ. Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 740-7. PMID 10411344 DOI: 10.1097/00005072-199907000-00008  0.364
1999 Ballard C, Holmes C, McKeith I, Neill D, O'Brien J, Cairns N, Lantos P, Perry E, Ince P, Perry R. Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease. The American Journal of Psychiatry. 156: 1039-45. PMID 10401449 DOI: 10.1176/Ajp.156.7.1039  0.43
1999 Armstrong RA, Cairns NJ, Lantos PL. Clustering of cerebral cortical lesions in patients with corticobasal degeneration. Neuroscience Letters. 268: 5-8. PMID 10400064 DOI: 10.1016/S0304-3940(99)00309-2  0.361
1999 Greber S, Lubec G, Cairns N, Fountoulakis M. Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down Syndrome and Alzheimer's disease Electrophoresis. 20: 928-934. PMID 10344268 DOI: 10.1002/(Sici)1522-2683(19990101)20:4/5<928::Aid-Elps928>3.0.Co;2-Z  0.416
1999 Holmes C, Cairns N, Lantos PL, Mann A. Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies. British Journal of Psychiatry. 174: 45-50. PMID 10211150 DOI: 10.1192/Bjp.174.1.45  0.421
1999 Labudova O, Cairns N, Koeck T, Kitzmueller E, Rink H, Lubec G. Thyroid stimulating hormone — Receptor overexpression in brain of patients with Down Syndrome and Alzheimer's disease Life Sciences. 64: 1037-1044. PMID 10210286 DOI: 10.1016/S0024-3205(99)00030-2  0.322
1999 Fukutani Y, Cairns NJ, Everall IP, Chadwick A, Isaki K, Lantos PL. Cerebellar dentate nucleus in Alzheimer's disease with myoclonus. Dementia and Geriatric Cognitive Disorders. 10: 81-8. PMID 10026380  0.325
1999 Lubec G, Labudova O, Cairns N, Fountoulakis M. Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome. Neuroscience Letters. 260: 141-145. PMID 10025719 DOI: 10.1016/S0304-3940(98)00952-5  0.366
1999 Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C, Liolitsa D, Vahidassr D, Powell J, McGleenon B, Liddell M, Plomin R, Dynan K, Williams N, Neal J, ... Cairns NJ, et al. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genetics. 21: 71-2. PMID 9916793 DOI: 10.1038/5009  0.425
1999 Lantos PL, Cairns NJ, Harvev R, Rossor MN. Familial Alzheimer's disease and Lewy body pathology Journal of Neuropathology and Experimental Neurology. 58: 514. DOI: 10.1097/00005072-199905000-00031  0.43
1999 Labudova O, Kitzmueller E, Rink H, Cairns N, Lubec G. Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease. Clinical Science. 96: 279-285. DOI: 10.1042/Cs0960279  0.342
1999 Armstrong RA, Cairns NJ, Lantos PL. Degeneration of cortical neurons associated with diffuse beta-amyloid (Abeta) deposits in Alzheimer’s disease Neuroscience Research Communications. 24: 89-97. DOI: 10.1002/(Sici)1520-6769(199903/04)24:2<89::Aid-Nrc4>3.0.Co;2-E  0.358
1998 Armstrong RA, Cairns NJ, Lantos PL. Spatial distribution of diffuse, primitive, and classic amyloid-beta deposits and blood vessels in the upper laminae of the frontal cortex in Alzheimer disease. Alzheimer Disease and Associated Disorders. 12: 378-83. PMID 9876969 DOI: 10.1097/00002093-199812000-00021  0.327
1998 Kehoe PG, Williams H, Holmans P, Wilcock G, Cairns NJ, Neal J, Owen MJ. The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease. Journal of Medical Genetics. 35: 1034-5. PMID 9863603 DOI: 10.1136/Jmg.35.12.1034  0.385
1998 Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, et al. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. The American Journal of Pathology. 153: 1365-70. PMID 9811326 DOI: 10.1016/S0002-9440(10)65722-7  0.363
1998 Labudova O, Krapfenbauer K, Moenkemann H, Rink H, Kitzmüller E, Cairns N, Lubec G. Decreased transcription factor junD in brains of patients with Down syndrome Neuroscience Letters. 252: 159-162. PMID 9739985 DOI: 10.1016/S0304-3940(98)00569-2  0.383
1998 Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neuroscience Letters. 251: 205-8. PMID 9726379 DOI: 10.1016/S0304-3940(98)00504-7  0.359
1998 Hermon M, Cairns N, Egly JM, Fery A, Labudova O, Lubec G. Expression of DNA excision-repair-cross-complementing proteins p80 and p89 in brain of patients with Down Syndrome and Alzheimer's disease. Neuroscience Letters. 251: 45-8. PMID 9714461 DOI: 10.1016/S0304-3940(98)00488-1  0.344
1998 Armstrong RA, Cairns NJ, Lantos PL. Clustering of Pick bodies in patients with Pick's disease. Neuroscience Letters. 242: 81-4. PMID 9533399 DOI: 10.1016/S0304-3940(98)00052-4  0.355
1998 Armstrong RA, Cairns NJ, Lantos PL. The spatial patterns of Lewy bodies, senile plaques, and neurofibrillary tangles in dementia with Lewy bodies. Experimental Neurology. 150: 122-7. PMID 9514834 DOI: 10.1006/Exnr.1997.6761  0.376
1998 Armstrong R, Cairns N, Lantos P. A comparison of histological and immunohistochemical methods for quantifying the pathological lesions of Pick's disease Neuropathology. 18: 295-300. DOI: 10.1111/J.1440-1789.1998.Tb00118.X  0.333
1998 Armstrong RA, Cairns NJ, Lantos PL. The spatial pattern of β‐amyloid (Aβ) deposits in Alzheimer's disease patients is related to apolipoprotein genotype Neuroscience Research Communications. 22: 99-106. DOI: 10.1002/(Sici)1520-6769(199803/04)22:2<99::Aid-Nrc5>3.0.Co;2-K  0.358
1997 Marshall KA, Daniel SE, Cairns N, Jenner P, Halliwell B. Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: studies on Parkinson's and incidental Lewy body disease. Biochemical and Biophysical Research Communications. 240: 84-7. PMID 9367887 DOI: 10.1006/Bbrc.1997.7604  0.356
1997 Fukutani Y, Sasaki K, Mukai M, Matsubara R, Isaki K, Cairns NJ. Neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial Alzheimer's disease: a case study. Psychiatry and Clinical Neurosciences. 51: 227-31. PMID 9316169 DOI: 10.1111/J.1440-1819.1997.Tb02588.X  0.372
1997 Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL. Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease. Neuroscience Letters. 230: 49-52. PMID 9259461 DOI: 10.1016/S0304-3940(97)00474-6  0.427
1997 Armstrong RA, Cairns NJ, Lantos PL. beta-Amyloid (A beta) deposition in the medial temporal lobe of patients with dementia with Lewy bodies. Neuroscience Letters. 227: 193-6. PMID 9185683 DOI: 10.1016/S0304-3940(97)00343-1  0.426
1997 Fukutani Y, Cairns NJ, Rossor MN, Lantos PL. Cerebellar pathology in sporadic and familial Alzheimer's disease including APP 717 (Val-->Ile) mutation cases: a morphometric investigation. Journal of the Neurological Sciences. 149: 177-84. PMID 9171327 DOI: 10.1016/S0022-510X(97)05399-9  0.413
1997 Armstrong RA, Cairns NJ, Lantos PL. Dementia with Lewy bodies: clustering of Lewy bodies in human patients. Neuroscience Letters. 224: 41-4. PMID 9132686 DOI: 10.1016/S0304-3940(97)13451-6  0.347
1997 Tysoe C, Whittaker J, Cairns NJ, Atkinson PF, Harrington CR, Xuereb J, Wilcock G, Rubinsztein DC. Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease. Neuroscience Letters. 222: 68-9. PMID 9121726 DOI: 10.1016/S0304-3940(97)13339-0  0.383
1997 Cairns NJ, Atkinson PF, Kovács T, Lees AJ, Daniel SE, Lantos PL. Apolipoprotein E e4 allele frequency in patients with multiple system atrophy. Neuroscience Letters. 221: 161-4. PMID 9121689 DOI: 10.1016/S0304-3940(96)13316-4  0.371
1997 Lyras L, Cairns NJ, Jenner A, Jenner P, Halliwell B. An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease. Journal of Neurochemistry. 68: 2061-9. PMID 9109533 DOI: 10.1046/J.1471-4159.1997.68052061.X  0.362
1997 Sasaki K, Fukutani Y, Mukai M, Cairns NJ, Isaki K. Neurons and neurofibrillary tangles in the hippocampal cortex in familial and sporadic Alzheimer's disease Neuropathology. 17: 301-306. DOI: 10.1111/J.1440-1789.1997.Tb00057.X  0.343
1997 Armstrong RA, Cairns NJ, Lantos PL. Laminar distribution of cortical Lewy bodies and neurofibrillary tangles in dementia with Lewy bodies Neuroscience Research Communications. 21: 145-152. DOI: 10.1002/(Sici)1520-6769(199709/10)21:2<145::Aid-Nrc218>3.0.Co;2-L  0.313
1996 Bernert G, Nemethova M, Herrera-Marschitz M, Cairns N, Lubec G. Decreased cyclin dependent kinase in brain of patients with Down syndrome. Neuroscience Letters. 216: 68-70. PMID 8892394 DOI: 10.1016/0304-3940(96)12988-8  0.382
1996 Fukutani Y, Cairns NJ, Rossor MN, Lantos PL. Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease. Neuroscience Letters. 214: 33-6. PMID 8873125 DOI: 10.1016/0304-3940(96)12875-5  0.377
1996 Gattaz WF, Levy R, Cairns NJ, Förstl H, Braus DF, Maras A. [Relevance of metabolism of membrane phospholipids for Alzheimer dementia]. Fortschritte Der Neurologie-Psychiatrie. 64: 8-12. PMID 8850090 DOI: 10.1055/S-2007-996367  0.314
1996 Rezaie P, Cairns NJ, Chadwick A, Lantos PL. Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease. Neuroscience Letters. 212: 111-4. PMID 8832651 DOI: 10.1016/0304-3940(96)12775-0  0.37
1996 Gattaz WF, Cairns NJ, Levy R, Förstl H, Braus DF, Maras A. Decreased phospholipase A2 activity in the brain and in platelets of patients with Alzheimer's disease. European Archives of Psychiatry and Clinical Neuroscience. 246: 129-31. PMID 8739397 DOI: 10.1007/Bf02189113  0.336
1996 Armstrong RA, Cairns NJ, Myers D, Smith CU, Lantos PL, Rossor MN. A comparison of beta-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 35-41. PMID 8731380 DOI: 10.1006/Neur.1996.0005  0.314
1996 Armstrong RA, Cairns NJ, Patel R, Lantos PL, Rossor MN. Relationships between beta-amyloid (A beta) deposits and blood vessels in patients with sporadic and familial Alzheimer's disease. Neuroscience Letters. 207: 171-4. PMID 8728477 DOI: 10.1016/0304-3940(96)12525-8  0.348
1996 Anwar R, Moynihan TP, Ardley H, Brindle N, Coletta PL, Cairns N, Markham AF, Robinson PA. Molecular analysis of the presenilin 1 (S182) gene in "sporadic" cases of Alzheimer's disease: identification and characterisation of unusual splice variants. Journal of Neurochemistry. 66: 1774-7. PMID 8627338 DOI: 10.1046/J.1471-4159.1996.66041774.X  0.441
1996 Cairns NJ, Fukutani Y, Chadwick A, Lantos PL. 777 Apolipoprotein E, phosphorylated tau and amyloid β-peptide deposition in Alzheimer's disease Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80779-2  0.391
1996 Fukutani Y, Cairns NJ, Everall IP, Chadwick A, Isaki K, Lantos PL. 471 The cerebellar dentate nucleus in Alzheimer's disease with and without myoclonus Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80473-8  0.435
1995 Fukutani Y, Kobayashi K, Nakamura I, Watanabe K, Isaki K, Cairns NJ. Neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and Alzheimer's disease. Neuroscience Letters. 200: 57-60. PMID 8584267 DOI: 10.1016/0304-3940(95)12083-G  0.4
1995 Gattaz WF, Maras A, Cairns NJ, Levy R, Förstl H. Decreased phospholipase A2 activity in Alzheimer brains. Biological Psychiatry. 37: 13-7. PMID 7893853 DOI: 10.1016/0006-3223(94)00123-K  0.453
1994 Förstl H, Levy R, Burns A, Luthert P, Cairns N. Pathways and patterns of cell loss in verified Alzheimer's disease : a factor and cluster analysis of clinico-pathological subgroups Behavioural Neurology. 7: 175-180. PMID 24487333 DOI: 10.3233/Ben-1994-73-411  0.366
1994 Oyama F, Cairns NJ, Shimada H, Oyama R, Titani K, Ihara Y. Down's syndrome: up-regulation of beta-amyloid protein precursor and tau mRNAs and their defective coordination. Journal of Neurochemistry. 62: 1062-6. PMID 8113792 DOI: 10.1046/J.1471-4159.1994.62031062.X  0.384
1994 Förstl H, Burns A, Levy R, Cairns N. Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease. British Journal of Psychiatry. 165: 53-59. PMID 7953058 DOI: 10.1192/Bjp.165.1.53  0.44
1993 Cairns NJ, Chadwick A, Lantos PL, Levy R, Rossor MN. Beta A4 protein deposition in familial Alzheimer's disease with the mutation in codon 717 of the beta A4 amyloid precursor protein gene and sporadic Alzheimer's disease. Neuroscience Letters. 149: 137-40. PMID 8474686 DOI: 10.1016/0304-3940(93)90755-A  0.441
1993 Förstl H, Burns A, Luthert P, Cairns N, Levy R. The Lewy-body variant of Alzheimer's disease : clinical and pathological findings British Journal of Psychiatry. 162: 385-392. PMID 8453435 DOI: 10.1192/Bjp.162.3.385  0.472
1993 Förstl H, Burns A, Levy R, Cairns N, Luthert P, Lantos P. Neuropathological correlates of behavioural disturbance in confirmed Alzheimer's disease. British Journal of Psychiatry. 163: 364-368. PMID 8401967 DOI: 10.1192/Bjp.163.3.364  0.45
1993 Förstl H, Burns A, Levy R, Cairns N. Neuropathological basis for drawing disability (constructional apraxia) in Alzheimer's disease Psychological Medicine. 23: 623-629. PMID 8234569 DOI: 10.1017/S003329170002540X  0.41
1992 Förstl H, Burns A, Cairns N, Luthert P, Levy R. Basal ganglia mineralization in Alzheimer's disease : a comparative study of clinical, neuroradiological and neuropathological findings Behavioural Neurology. 5: 53-57. PMID 24487663 DOI: 10.3233/Ben-1992-5110  0.444
1992 Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron. 8: 159-68. PMID 1530909 DOI: 10.1016/0896-6273(92)90117-V  0.385
1992 Förstl H, Burns A, Luthert P, Cairns N, Lantos P, Levy R. Clinical and neuropathological correlates of depression in Alzheimer's disease. Psychological Medicine. 22: 877-884. PMID 1488485 DOI: 10.1017/S0033291700038459  0.383
1992 Cairns NJ, Chadwick A, Luthert PJ, Lantos PL. Astrocytosis, beta A4-protein deposition and paired helical filament formation in Alzheimer's disease. Journal of the Neurological Sciences. 112: 68-75. PMID 1469442 DOI: 10.1016/0022-510X(92)90134-7  0.394
1992 Förstl H, Burns A, Levy R, Cairns N, Luthert P, Lantos P. Neurologic signs in Alzheimer's disease. Results of a prospective clinical and neuropathologic study. Jama Neurology. 49: 1038-1042. PMID 1417511 DOI: 10.1001/Archneur.1992.00530340054018  0.402
1991 Cairns NJ, Chadwick A, Luthert PJ, Lantos PL. beta-Amyloid protein load is relatively uniform throughout neocortex and hippocampus in elderly Alzheimer's disease patients. Neuroscience Letters. 129: 115-8. PMID 1922960 DOI: 10.1016/0304-3940(91)90733-A  0.414
1991 Hanger DP, Brion JP, Gallo JM, Cairns NJ, Luthert PJ, Anderton BH. Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated. The Biochemical Journal. 275: 99-104. PMID 1826835 DOI: 10.1042/Bj2750099  0.441
1991 Förstl H, Cairns N, Burns A, Luthert P. Medical disorders in Alzheimer's disease and vascular dementia. Postgraduate Medical Journal. 67: 742-744. PMID 1754524 DOI: 10.1136/Pgmj.67.790.742  0.416
1991 Armstrong RA, Myers D, Smith CUM, Cairns NJ, Luthert PJ. Alzheimer's disease: the relationship between the density of senile plaques, neurofibrillary tangles and A4 protein in human patients Neuroscience Letters. 123: 141-143. PMID 1709265 DOI: 10.1016/0304-3940(91)90915-G  0.325
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