Timothy Arthur James Haystead - Publications

Affiliations: 
1991-1999 Pharmacology University of Virginia, Charlottesville, VA 
 2000- Pharmacology & Cancer Biology Duke University, Durham, NC 
Area:
Biochemistry
Website:
https://medschool.duke.edu/about-us/our-faculty/timothy-arthur-james-haystead

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Damhofer H, Tatar T, Southgate B, Scarneo S, Agger K, Shlyueva D, Uhrbom L, Morrison GM, Hughes PF, Haystead T, Pollard SM, Helin K. TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers. Cell Death & Disease. 15: 273. PMID 38632238 DOI: 10.1038/s41419-024-06654-1  0.654
2023 Haystead T, Lee E, Cho K, Gullickson G, Hughes P, Krafsur G, Freeze R, Scarneo S. Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein. Scientific Reports. 13: 22873. PMID 38129491 DOI: 10.1038/s41598-023-49077-2  0.788
2023 Freeze R, Yang KW, Haystead T, Hughes P, Scarneo S. Delineation of the distinct inflammatory signaling roles of TAK1 and JAK1/3 in the CIA model of rheumatoid arthritis. Pharmacology Research & Perspectives. 11: e01124. PMID 37564034 DOI: 10.1002/prp2.1124  0.789
2023 Bale S, Verma P, Yalavarthi B, Scarneo SA, Hughes PF, Amin MA, Tsou PS, Khanna D, Haystead TA, Bhattacharyya S, Varga J. Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis. Jci Insight. PMID 37306632 DOI: 10.1172/jci.insight.165358  0.777
2022 Kaneko K, Nagata H, Yang XY, Ginzel J, Hartman Z, Everitt J, Hughes P, Haystead T, Morse M, Lyerly HK, Osada T. A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity. Cancers. 14. PMID 36497243 DOI: 10.3390/cancers14235762  0.614
2022 Scarneo S, Hughes P, Freeze R, Yang K, Totzke J, Haystead T. Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis. Acs Chemical Biology. PMID 35234444 DOI: 10.1021/acschembio.1c00788  0.775
2021 Wang Y, Scarneo SA, Kim SH, Zhang X, Chen J, Yang KW, Hughes P, Haystead T, Nackley AG. Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain. Pain. PMID 34995041 DOI: 10.1097/j.pain.0000000000002511  0.786
2021 Goswami R, Russell VS, Tu JJ, Thomas C, Hughes P, Kelly F, Langel SN, Steppe J, Palmer SM, Haystead T, Blasi M, Permar SR. Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells. Iscience. 103412. PMID 34786537 DOI: 10.1016/j.isci.2021.103412  0.62
2021 Osada T, Crosby EJ, Kaneko K, Snyder JC, Ginzel JD, Acharya CR, Yang XY, Polascik TJ, Spasojevic I, Nelson RC, Hobeika A, Hartman ZC, Neckers LM, Rogatko A, Hughes PF, ... ... Haystead T, et al. HSP90-specific nIR probe identifies aggressive prostate cancers: translation from preclinical models to a human phase I study. Molecular Cancer Therapeutics. PMID 34675120 DOI: 10.1158/1535-7163.MCT-21-0334  0.611
2021 Woodford MR, Baker-Williams AJ, Sager RA, Backe SJ, Blanden AR, Hashmi F, Kancherla P, Gori A, Loiselle DR, Castelli M, Serapian SA, Colombo G, Haystead TA, Jensen SM, Stetler-Stevenson WG, et al. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology. 28: 662-670. PMID 34381247 DOI: 10.1038/s41594-021-00633-2  0.714
2021 Wang R, Alvarez DA, Crouch BT, Pilani A, Lam C, Zhu C, Hughes P, Katz D, Haystead T, Ramanujam N. Understanding the sources of errors in Hsp90 molecular imaging for rapid-on-site breast cancer diagnosis. Biomedical Optics Express. 12: 2299-2311. PMID 33996230 DOI: 10.1364/BOE.418818  0.612
2021 Smith AD, Garcia-Santamarina S, Ralle M, Loiselle DR, Haystead TA, Thiele DJ. Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase. The Journal of Biological Chemistry. 100391. PMID 33567338 DOI: 10.1016/j.jbc.2021.100391  0.715
2020 Dong B, Jaeger AM, Hughes PF, Loiselle DR, Hauck JS, Fu Y, Haystead TA, Huang J, Thiele DJ. Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1. Science Translational Medicine. 12. PMID 33328331 DOI: 10.1126/scitranslmed.abb5647  0.774
2020 Kaneko K, Osada T, Morse MA, Gwin WR, Ginzel JD, Snyder JC, Yang XY, Liu CX, Diniz MA, Bodoor K, Hughes PF, Haystead TA, Lyerly HK. Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors. Communications Biology. 3: 226. PMID 32385408 DOI: 10.1038/s42003-020-0956-7  0.789
2019 Crouch BT, Gallagher J, Wang R, Duer J, Hall A, Soo MS, Hughes P, Haystead T, Ramanujam N. Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer. Scientific Reports. 9: 3461. PMID 30837677 DOI: 10.1038/S41598-019-40252-Y  0.657
2019 Sager RA, Woodford MR, Backe SJ, Makedon AM, Baker-Williams AJ, DiGregorio BT, Loiselle DR, Haystead TA, Zachara NE, Prodromou C, Bourboulia D, Schmidt LS, Linehan WM, Bratslavsky G, Mollapour M. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Reports. 26: 1344-1356.e5. PMID 30699359 DOI: 10.1016/J.Celrep.2019.01.018  0.735
2018 Neckers L, Blagg B, Haystead T, Trepel JB, Whitesell L, Picard D. Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development. Cell Stress & Chaperones. PMID 29392504 DOI: 10.1007/S12192-018-0877-2  0.41
2018 Bellaye PS, Shimbori C, Yanagihara T, Carlson DA, Hughes P, Upagupta C, Sato S, Wheildon N, Haystead T, Ask K, Kolb M. Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis. The European Respiratory Journal. 51. PMID 29386344 DOI: 10.1183/13993003.00386-2017  0.702
2018 Posfai D, Eubanks AL, Keim AI, Lu KY, Wang GZ, Hughes PF, Kato N, Haystead TA, Derbyshire ER. Identification of Hsp90 inhibitors with anti-Plasmodium activity. Antimicrobial Agents and Chemotherapy. PMID 29339390 DOI: 10.1128/Aac.01799-17  0.636
2018 Dushukyan N, Daneshvar M, Sager R, Woodford M, Baker-Williams A, Chisholm J, Loiselle D, Truman A, Haystead T, Shapiro O, Bourboulia D, Bratslavsky G, Mollapour M. PD46-11 PHOSPHORYLATION AND UBIQUITINATION REGULATE PROTEIN PHOSPHATASE-5 ACTIVITY AND ITS PROSURVIVAL ROLE IN KIDNEY CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2159  0.711
2017 Crouch B, Murphy H, Belonwu S, Martinez A, Gallagher J, Hall A, Soo MS, Lee M, Hughes P, Haystead T, Ramanujam N. Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens. Scientific Reports. 7: 17487. PMID 29235516 DOI: 10.1038/S41598-017-17832-X  0.669
2017 Dushukyan N, Dunn DM, Sager RA, Woodford MR, Loiselle DR, Daneshvar M, Baker-Williams AJ, Chisholm JD, Truman AW, Vaughan CK, Haystead TA, Bratslavsky G, Bourboulia D, Mollapour M. Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer. Cell Reports. 21: 1883-1895. PMID 29141220 DOI: 10.1016/J.Celrep.2017.10.074  0.739
2017 Osada T, Kaneko K, Gwin WR, Morse MA, Hobeika A, Pogue BW, Hartman ZC, Hughes PF, Haystead T, Lyerly HK. In vivo detection of HSP90 identifies breast cancers with aggressive behavior. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28993342 DOI: 10.1158/1078-0432.Ccr-17-1453  0.655
2017 Kulkarni MM, Ratcliff AN, Bhat M, Alwarawrah Y, Hughes P, Arcos J, Loiselle D, Torrelles JB, Funderburg NT, Haystead TA, Kwiek JJ. Cellular fatty acid synthase is required for late stages of HIV-1 replication. Retrovirology. 14: 45. PMID 28962653 DOI: 10.1186/S12977-017-0368-Z  0.774
2017 Crowe LB, Hughes PF, Alcorta DA, Osada T, Smith AP, Totzke J, Loiselle DR, Lutz ID, Gargesha M, Roy D, Roques J, Darr D, Lyerly HK, Spector NL, Haystead TA. A fluorescent Hsp90 probe demonstrates the unique association between extracellular Hsp90 and malignancy in vivo. Acs Chemical Biology. PMID 28103010 DOI: 10.1021/Acschembio.7B00006  0.767
2017 Ogawa M, Tomita Y, Nakamura Y, Lee MJ, Lee S, Tomita S, Nagaya T, Sato K, Yamauchi T, Iwai H, Kumar A, Haystead T, Shroff H, Choyke PL, Trepel JB, et al. Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity. Oncotarget. PMID 28060726 DOI: 10.18632/Oncotarget.14425  0.319
2017 Cobb M, Hunter L, Carlson D, Darr D, Haystead T, Baines AT. Abstract 524: Characterizing thein vitroandin vivoeffects of the PIM kinase inhibitor HS140 in triple-negative human breast cancer Cancer Research. 77: 524-524. DOI: 10.1158/1538-7445.Am2017-524  0.362
2017 Osada T, Kaneko K, Hartman Z, Hobeika A, Hughes P, Haystead T, Morse M, Lyerly HK. Abstract 1859: Hsp90 targeted near infrared molecular imaging to detect mammografically occult invasive lobular breast cancer Cancer Research. 77: 1859-1859. DOI: 10.1158/1538-7445.Am2017-1859  0.677
2016 Woodford MR, Dunn DM, Blanden AR, Capriotti D, Loiselle D, Prodromou C, Panaretou B, Hughes PF, Smith A, Ackerman W, Haystead TA, Loh SN, Bourboulia D, Schmidt LS, Marston Linehan W, et al. The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding. Nature Communications. 7: 12037. PMID 27353360 DOI: 10.1038/Ncomms12037  0.811
2016 Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chemical Biology. PMID 27265747 DOI: 10.1016/J.Chembiol.2016.04.011  0.777
2016 Martin MD, Baker JD, Suntharalingam A, Nordhues BA, Shelton LB, Zheng D, Sabbagh JJ, Haystead TA, Gestwicki JE, Dickey CA. Inhibition of Both Hsp70 Activity and Tau Aggregation In Vitro Best Predicts Tau Lowering Activity of Small Molecules. Acs Chemical Biology. PMID 27177119 DOI: 10.1021/Acschembio.6B00223  0.326
2016 Howe MK, Speer BL, Hughes PF, Loiselle DR, Vasudevan S, Haystead TA. An Inducible Heat Shock Protein 70 Small Molecule Inhibitor Demonstrates Anti-Dengue Virus Activity, Validating Hsp70 as a Host Antiviral Target. Antiviral Research. PMID 27058774 DOI: 10.1016/J.Antiviral.2016.03.017  0.782
2015 MacDonald JA, Sutherland C, Carlson DA, Bhaidani S, Al-Ghabkari A, Sward K, Haystead TA, Walsh MP. A Small Molecule Pyrazolo[3,4-d]pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle. Molecular Pharmacology. PMID 26464323 DOI: 10.1124/Mol.115.100529  0.62
2015 Dunn DM, Woodford MR, Truman AW, Jensen SM, Schulman J, Caza T, Remillard TC, Loiselle D, Wolfgeher D, Blagg BS, Franco L, Haystead TA, Daturpalli S, Mayer MP, Trepel JB, et al. c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells. Cell Reports. 12: 1006-18. PMID 26235616 DOI: 10.1016/J.Celrep.2015.07.004  0.739
2015 Lontay B, Bodoor K, Sipos A, Weitzel DH, Loiselle D, Safi R, Zheng D, Devente J, Hickner RC, McDonnell DP, Ribar T, Haystead TA. Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice. The Journal of Biological Chemistry. 290: 17985-98. PMID 26048986 DOI: 10.1074/Jbc.M115.658120  0.775
2015 Darr D, Alwarawrah Y, Hunter L, Loiselle D, Hughes P, Haystead T. Abstract 4457: Novel fatty-acid synthase inhibitor in combination with platinum-based therapy provides increased tumor killing efficacy in luminal breast murine model Cancer Research. 75: 4457-4457. DOI: 10.1158/1538-7445.Am2015-4457  0.777
2014 Howe MK, Bodoor K, Carlson DA, Hughes PF, Alwarawrah Y, Loiselle DR, Jaeger AM, Darr DB, Jordan JL, Hunter LM, Molzberger ET, Gobillot TA, Thiele DJ, Brodsky JL, Spector NL, ... Haystead TA, et al. Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70. Chemistry & Biology. 21: 1648-59. PMID 25500222 DOI: 10.1016/J.Chembiol.2014.10.016  0.805
2014 Rathore AP, Haystead T, Das PK, Merits A, Ng ML, Vasudevan SG. Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo. Antiviral Research. 103: 7-16. PMID 24388965 DOI: 10.1016/J.Antiviral.2013.12.010  0.347
2013 Yasuda K, Zhang H, Loiselle D, Haystead T, Macara IG, Mili S. The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules. The Journal of Cell Biology. 203: 737-46. PMID 24297750 DOI: 10.1083/Jcb.201306058  0.71
2013 Carlson DA, Franke AS, Weitzel DH, Speer BL, Hughes PF, Hagerty L, Fortner CN, Veal JM, Barta TE, Zieba BJ, Somlyo AV, Sutherland C, Deng JT, Walsh MP, MacDonald JA, ... Haystead TA, et al. Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. Acs Chemical Biology. 8: 2715-23. PMID 24070067 DOI: 10.1021/Cb400407C  0.795
2013 Barrott JJ, Hughes PF, Osada T, Yang XY, Hartman ZC, Loiselle DR, Spector NL, Neckers L, Rajaram N, Hu F, Ramanujam N, Vaidyanathan G, Zalutsky MR, Lyerly HK, Haystead TA. Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells. Chemistry & Biology. 20: 1187-97. PMID 24035283 DOI: 10.1016/J.Chembiol.2013.08.004  0.804
2013 Barrott JJ, Haystead TA. Hsp90, an unlikely ally in the war on cancer. The Febs Journal. 280: 1381-96. PMID 23356585 DOI: 10.1111/Febs.12147  0.776
2012 LaMonte G, Philip N, Reardon J, Lacsina JR, Majoros W, Chapman L, Thornburg CD, Telen MJ, Ohler U, Nicchitta CV, Haystead T, Chi JT. Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance. Cell Host & Microbe. 12: 187-99. PMID 22901539 DOI: 10.1016/J.Chom.2012.06.007  0.719
2012 Hughes PF, Barrott JJ, Carlson DA, Loiselle DR, Speer BL, Bodoor K, Rund LA, Haystead TA. A highly selective Hsp90 affinity chromatography resin with a cleavable linker. Bioorganic & Medicinal Chemistry. 20: 3298-305. PMID 22520629 DOI: 10.1016/J.Bmc.2012.03.043  0.788
2012 Duncan JS, Haystead TA, Litchfield DW. Chemoproteomic characterization of protein kinase inhibitors using immobilized ATP. Methods in Molecular Biology (Clifton, N.J.). 795: 119-34. PMID 21960219 DOI: 10.1007/978-1-61779-337-0_8  0.46
2011 Bodoor K, Lontay B, Safi R, Weitzel DH, Loiselle D, Wei Z, Lengyel S, McDonnell DP, Haystead TA. Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. The Journal of Biological Chemistry. 286: 31839-51. PMID 21771785 DOI: 10.1074/Jbc.M111.270397  0.785
2011 Iioka H, Loiselle D, Haystead TA, Macara IG. Efficient detection of RNA-protein interactions using tethered RNAs. Nucleic Acids Research. 39: e53. PMID 21300640 DOI: 10.1093/Nar/Gkq1316  0.675
2011 Weitzel DH, Chambers J, Haystead TA. Phosphorylation-dependent control of ZIPK nuclear import is species specific. Cellular Signalling. 23: 297-303. PMID 20854903 DOI: 10.1016/J.Cellsig.2010.09.016  0.648
2010 Fadden P, Huang KH, Veal JM, Steed PM, Barabasz AF, Foley B, Hu M, Partridge JM, Rice J, Scott A, Dubois LG, Freed TA, Silinski MA, Barta TE, Hughes PF, ... ... Haystead TA, et al. Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90. Chemistry & Biology. 17: 686-94. PMID 20659681 DOI: 10.1016/J.Chembiol.2010.04.015  0.767
2010 Lontay B, Bodoor K, Weitzel DH, Loiselle D, Fortner C, Lengyel S, Zheng D, Devente J, Hickner R, Haystead TA. Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy. The Journal of Biological Chemistry. 285: 29357-66. PMID 20634291 DOI: 10.1074/Jbc.M110.143966  0.787
2009 Borman MA, Freed TA, Haystead TA, Macdonald JA. The role of the calponin homology domain of smoothelin-like 1 (SMTNL1) in myosin phosphatase inhibition and smooth muscle contraction. Molecular and Cellular Biochemistry. 327: 93-100. PMID 19219534 DOI: 10.1007/S11010-009-0047-Z  0.777
2008 Doerig C, Billker O, Haystead T, Sharma P, Tobin AB, Waters NC. Protein kinases of malaria parasites: an update. Trends in Parasitology. 24: 570-7. PMID 18845480 DOI: 10.1016/J.Pt.2008.08.007  0.387
2008 Howard BA, Sempowski GD, Scearce RM, Liao HX, Lee DM, Lam GK, Chen H, Fadden P, Haystead T, Haynes BF. Murine CD7 shares antigenic cross-reactivity with HSP-60. Hybridoma (2005). 27: 81-9. PMID 18642672 DOI: 10.1089/Hyb.2007.0553  0.748
2008 Higgins MJ, Loiselle D, Haystead TA, Graves LM. Human cytidine triphosphate synthetase 1 interacting proteins Nucleosides, Nucleotides and Nucleic Acids. 27: 850-857. PMID 18600551 DOI: 10.1080/15257770802146502  0.709
2008 Wooldridge AA, Fortner CN, Lontay B, Akimoto T, Neppl RL, Facemire C, Datto MB, Kwon A, McCook E, Li P, Wang S, Thresher RJ, Miller SE, Perriard JC, Gavin TP, ... ... Haystead TA, et al. Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. The Journal of Biological Chemistry. 283: 11850-9. PMID 18310078 DOI: 10.1074/Jbc.M708628200  0.706
2008 Duncan JS, Gyenis L, Lenehan J, Bretner M, Graves LM, Haystead TA, Litchfield DW. An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets. Molecular & Cellular Proteomics : McP. 7: 1077-88. PMID 18258654 DOI: 10.1074/Mcp.M700559-Mcp200  0.323
2007 Borman MA, MacDonald JA, Haystead TA. Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 85: 111-20. PMID 17464351 DOI: 10.1139/o06-209  0.73
2007 Philip N, Haystead TA. Characterization of a UBC13 kinase in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America. 104: 7845-50. PMID 17452636 DOI: 10.1073/Pnas.0611601104  0.778
2007 Walker JR, Gnanam AJ, Blinkova AL, Hermandson MJ, Karymov MA, Lyubchenko YL, Graves PR, Haystead TA, Linse KD. Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. Molecular Microbiology. 63: 629-43. PMID 17302797 DOI: 10.1111/J.1365-2958.2006.05494.X  0.632
2007 Moorhead GB, Haystead TA, MacKintosh C. Synthesis and use of the protein phosphatase affinity matrices microcystin-sepharose and microcystin-biotin-sepharose. Methods in Molecular Biology (Clifton, N.J.). 365: 39-45. PMID 17200552 DOI: 10.1385/1-59745-267-X:39  0.357
2007 Wooldridge AA, Haystead TA. Real-time in vivo proteomic identification of novel kinase substrates in smooth muscle. Methods in Molecular Biology (Clifton, N.J.). 357: 235-52. PMID 17172692 DOI: 10.1385/1-59745-214-9:235  0.682
2007 Hagerty L, Weitzel DH, Chambers J, Fortner CN, Brush MH, Loiselle D, Hosoya H, Haystead TA. ROCK1 phosphorylates and activates zipper-interacting protein kinase. The Journal of Biological Chemistry. 282: 4884-93. PMID 17158456 DOI: 10.1074/Jbc.M609990200  0.799
2007 Kwiek NC, Thacker DF, Haystead TA. Dual kinase-mediated regulation of PITK by CaMKII and GSK3. Cellular Signalling. 19: 593-9. PMID 17023142 DOI: 10.1016/J.Cellsig.2006.08.009  0.803
2006 Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. The Journal of Clinical Investigation. 116: 2218-25. PMID 16878172 DOI: 10.1172/Jci16980  0.711
2006 Haystead TA. The purinome, a complex mix of drug and toxicity targets. Current Topics in Medicinal Chemistry. 6: 1117-27. PMID 16842150 DOI: 10.2174/156802606777812059  0.436
2006 Kwiek NC, Thacker DF, Datto MB, Megosh HB, Haystead TA. PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K. Cellular Signalling. 18: 1769-78. PMID 16564677 DOI: 10.1016/J.Cellsig.2006.01.019  0.798
2006 Hagerty L, Haystead TA. Delineating signal transduction pathways in smooth muscle through focused proteomics. Expert Review of Proteomics. 3: 75-85. PMID 16445352 DOI: 10.1586/14789450.3.1.75  0.78
2005 Hilder TL, Carlson GM, Haystead TA, Krebs EG, Graves LM. Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase. Molecular and Cellular Biochemistry. 275: 233-42. PMID 16335803 DOI: 10.1007/S11010-005-2411-Y  0.548
2005 Kremer BE, Haystead T, Macara IG. Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Molecular Biology of the Cell. 16: 4648-59. PMID 16093351 DOI: 10.1091/Mbc.E05-03-0267  0.312
2005 Haystead TA. ZIP kinase, a key regulator of myosin protein phosphatase 1. Cellular Signalling. 17: 1313-22. PMID 16005610 DOI: 10.1016/J.Cellsig.2005.05.008  0.388
2005 Graves PR, Winkfield KM, Haystead TA. Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. The Journal of Biological Chemistry. 280: 9363-74. PMID 15611134 DOI: 10.1074/Jbc.M412538200  0.782
2004 Lascola CD, Song AW, Haystead TA, Warner DS, Verleysen K, Freed TA, Provenzale JM. Changes in magnetization transfer MRI correlate with spreading depression-induced astroglial reactivity and increased protein expression in mice. Ajr. American Journal of Roentgenology. 183: 1791-7. PMID 15547231 DOI: 10.2214/Ajr.183.6.01831791  0.76
2004 Borman MA, MacDonald JA, Haystead TA. Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins. Febs Letters. 573: 207-13. PMID 15327999 DOI: 10.1016/J.Febslet.2004.08.002  0.738
2004 Wooldridge AA, MacDonald JA, Erdodi F, Ma C, Borman MA, Hartshorne DJ, Haystead TA. Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides. The Journal of Biological Chemistry. 279: 34496-504. PMID 15194681 DOI: 10.1074/Jbc.M405957200  0.803
2004 Erikson E, Haystead TA, Qian YW, Maller JL. A feedback loop in the polo-like kinase activation pathway. The Journal of Biological Chemistry. 279: 32219-24. PMID 15166215 DOI: 10.1074/Jbc.M403840200  0.621
2004 Kwiek JJ, Haystead TA, Rudolph J. Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines. Biochemistry. 43: 4538-47. PMID 15078100 DOI: 10.1021/Bi035923W  0.667
2003 Ray R, Haystead TA. Phosphoproteome analysis in yeast. Methods in Enzymology. 366: 95-103. PMID 14674242 DOI: 10.1016/S0076-6879(03)66008-8  0.776
2003 Ray R, Haystead TA. Mixed peptide sequencing and the FASTF/FASTS algorithms. Methods in Enzymology. 366: 84-95. PMID 14674241 DOI: 10.1016/S0076-6879(03)66007-6  0.753
2003 Mackey AJ, Haystead TA, Pearson WR. CRP: Cleavage of Radiolabeled Phosphoproteins. Nucleic Acids Research. 31: 3859-61. PMID 12824437 DOI: 10.1093/Nar/Gkg513  0.322
2003 Graves PR, Haystead TA. A functional proteomics approach to signal transduction. Recent Progress in Hormone Research. 58: 1-24. PMID 12795412 DOI: 10.1210/Rp.58.1.1  0.706
2003 Soti C, Vermes A, Haystead TA, Csermely P. Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site. European Journal of Biochemistry / Febs. 270: 2421-8. PMID 12755697 DOI: 10.1046/J.1432-1033.2003.03610.X  0.33
2003 Corcoran EE, Joseph JD, MacDonald JA, Kane CD, Haystead TA, Means AR. Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences. The Journal of Biological Chemistry. 278: 10516-22. PMID 12538590 DOI: 10.1074/Jbc.M210642200  0.399
2002 Graves PR, Kwiek JJ, Fadden P, Ray R, Hardeman K, Coley AM, Foley M, Haystead TA. Discovery of novel targets of quinoline drugs in the human purine binding proteome. Molecular Pharmacology. 62: 1364-72. PMID 12435804 DOI: 10.1124/Mol.62.6.1364  0.788
2002 MacDonald JA, Mackey AJ, Pearson WR, Haystead TA. A strategy for the rapid identification of phosphorylation sites in the phosphoproteome. Molecular & Cellular Proteomics : McP. 1: 314-22. PMID 12096113 DOI: 10.1074/Mcp.M200002-Mcp200  0.345
2002 Murányi A, MacDonald JA, Deng JT, Wilson DP, Haystead TA, Walsh MP, Erdodi F, Kiss E, Wu Y, Hartshorne DJ. Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase. The Biochemical Journal. 366: 211-6. PMID 12030846 DOI: 10.1042/Bj20020401  0.385
2002 Borman MA, MacDonald JA, Murányi A, Hartshorne DJ, Haystead TA. Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition. The Journal of Biological Chemistry. 277: 23441-6. PMID 11976330 DOI: 10.1074/Jbc.M201597200  0.733
2002 Graves PR, Haystead TA. Molecular biologist's guide to proteomics. Microbiology and Molecular Biology Reviews : Mmbr. 66: 39-63; table of cont. PMID 11875127 DOI: 10.1128/Mmbr.66.1.39-63.2002  0.684
2001 Joberty G, Perlungher RR, Sheffield PJ, Kinoshita M, Noda M, Haystead T, Macara IG. Borg proteins control septin organization and are negatively regulated by Cdc42 Nature Cell Biology. 3: 861-866. PMID 11584266 DOI: 10.1038/Ncb1001-861  0.361
2001 MacDonald JA, Eto M, Borman MA, Brautigan DL, Haystead TA. Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase. Febs Letters. 493: 91-4. PMID 11287002 DOI: 10.1016/S0014-5793(01)02277-3  0.729
2001 De Nadal E, Fadden RP, Ruiz A, Haystead T, Ariño J. A Role for the Ppz Ser/Thr Protein Phosphatases in the Regulation of Translation Elongation Factor 1Bα Journal of Biological Chemistry. 276: 14829-14834. PMID 11278758 DOI: 10.1074/Jbc.M010824200  0.409
2000 Mothe-Satney I, Yang D, Fadden P, Haystead TA, Lawrence JC. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression. Molecular and Cellular Biology. 20: 3558-67. PMID 10779345 DOI: 10.1128/Mcb.20.10.3558-3567.2000  0.769
2000 Sanz P, Alms GR, Haystead TA, Carlson M. Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase. Molecular and Cellular Biology. 20: 1321-8. PMID 10648618 DOI: 10.1128/Mcb.20.4.1321-1328.2000  0.755
2000 Terry-Lorenzo RT, Inoue M, Connor JH, Haystead TA, Armbruster BN, Gupta RP, Oliver CJ, Shenolikar S. Neurofilament-L is a protein phosphatase-1-binding protein associated with neuronal plasma membrane and post-synaptic density. The Journal of Biological Chemistry. 275: 2439-46. PMID 10644697 DOI: 10.1074/Jbc.275.4.2439  0.345
1999 Alms GR, Sanz P, Carlson M, Haystead TA. Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome. The Embo Journal. 18: 4157-68. PMID 10428955 DOI: 10.1093/Emboj/18.15.4157  0.763
1998 Kihm AJ, Hershey JC, Haystead TA, Madsen CS, Owens GK. Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 14816-20. PMID 9843972 DOI: 10.1073/Pnas.95.25.14816  0.369
1998 Fadden P, Haystead TA, Lawrence JC. Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2. Febs Letters. 435: 105-9. PMID 9755868 DOI: 10.1016/S0014-5793(98)01047-3  0.778
1997 Brunn GJ, Fadden P, Haystead TA, Lawrence JC. The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus. The Journal of Biological Chemistry. 272: 32547-50. PMID 9405468 DOI: 10.1074/Jbc.272.51.32547  0.791
1997 Lawrence JC, Fadden P, Haystead TA, Lin TA. PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation. Advances in Enzyme Regulation. 37: 239-67. PMID 9381973 DOI: 10.1016/S0065-2571(96)00016-7  0.789
1997 Vernon SM, Campos MJ, Haystead T, Thompson MM, DiCorleto PE, Owens GK. Endothelial cell-conditioned medium downregulates smooth muscle contractile protein expression American Journal of Physiology - Cell Physiology. 272. PMID 9124302 DOI: 10.1152/Ajpcell.1997.272.2.C582  0.313
1997 Fadden P, Haystead TA, Lawrence JC. Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes. The Journal of Biological Chemistry. 272: 10240-7. PMID 9092573 DOI: 10.1074/Jbc.272.15.10240  0.774
1995 Hershey JC, Hautmann M, Thompson MM, Rothblum LI, Haystead TA, Owens GK. Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. The Journal of Biological Chemistry. 270: 25096-101. PMID 7559641 DOI: 10.1074/Jbc.270.42.25096  0.329
1994 Davies SP, Hawley SA, Woods A, Carling D, Haystead TA, Hardie DG. Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure. European Journal of Biochemistry / Febs. 223: 351-7. PMID 8055903 DOI: 10.1111/J.1432-1033.1994.Tb19001.X  0.556
1994 Lin TA, Kong X, Haystead TA, Pause A, Belsham G, Sonenberg N, Lawrence JC. PHAS-I as a link between mitogen-activated protein kinase and translation initiation. Science (New York, N.Y.). 266: 653-6. PMID 7939721 DOI: 10.1126/Science.7939721  0.39
1992 Wu J, Michel H, Rossomando A, Haystead T, Shabanwitz J, Hunt DF, Sturgill TW. Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle Biochemical Journal. 285: 701-705. PMID 1379797 DOI: 10.1042/Bj2850701  0.407
1991 Meier KE, Licciardi KA, Haystead TA, Krebs EG. Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells. The Journal of Biological Chemistry. 266: 1914-20. PMID 1988454  0.545
1990 Haystead TA, Weiel JE, Litchfield DW, Tsukitani Y, Fischer EH, Krebs EG. Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal. The Journal of Biological Chemistry. 265: 16571-80. PMID 2168895  0.523
1989 Haystead TA, Sim AT, Carling D, Honnor RC, Tsukitani Y, Cohen P, Hardie DG. Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature. 337: 78-81. PMID 2562908 DOI: 10.1038/337078A0  0.578
1986 Munday MR, Haystead TA, Holland R, Carling DA, Hardie DG. The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis. Biochemical Society Transactions. 14: 559-62. PMID 2874088  0.444
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