| Year |
Citation |
Score |
| 2022 |
Grogan A, Lucero EY, Jiang H, Rockman HA. Pathophysiology and pharmacology of G protein-coupled receptors in the heart. Cardiovascular Research. PMID 36534965 DOI: 10.1093/cvr/cvac171 |
0.369 |
|
| 2020 |
McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. Synthetic nanobodies as angiotensin receptor blockers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32753386 DOI: 10.1073/Pnas.2009029117 |
0.326 |
|
| 2020 |
Kim J, Grotegut CA, Wisler JW, Mao L, Rosenberg PB, Rockman HA, Lefkowitz RJ. The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility. Proceedings of the National Academy of Sciences of the United States of America. PMID 32414934 DOI: 10.1073/Pnas.1920310117 |
0.327 |
|
| 2020 |
Nielsen NR, Rangarajan KV, Mao L, Rockman HA, Caron KM. A Murine Model of Increased Coronary Sinus Pressure Induces Myocardial Edema with Cardiac Lymphatic Dilation and Fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32142379 DOI: 10.1152/Ajpheart.00436.2019 |
0.373 |
|
| 2018 |
Yu SM, Jean-Charles PY, Abraham DM, Kaur S, Gareri C, Mao L, Rockman HA, Shenoy SK. The deubiquitinase ubiquitin specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling. The Journal of Biological Chemistry. PMID 30538132 DOI: 10.1074/Jbc.Ra118.004926 |
0.468 |
|
| 2018 |
Wang J, Gareri C, Rockman HA. G-Protein-Coupled Receptors in Heart Disease. Circulation Research. 123: 716-735. PMID 30355236 DOI: 10.1161/Circresaha.118.311403 |
0.422 |
|
| 2018 |
Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, ... ... Rockman HA, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650 |
0.362 |
|
| 2018 |
Abraham DM, Lee TE, Watson LJ, Mao L, Chandok GS, Wang HG, Frangakis S, Pitt GS, Shah SH, Wolf MJ, Rockman HA. The two-pore-domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. The Journal of Clinical Investigation. PMID 30153110 DOI: 10.1172/Jci95945 |
0.442 |
|
| 2018 |
Wisler JW, Rockman HA, Lefkowitz RJ. Biased G Protein-Coupled Receptor Signaling: Changing the Paradigm of Drug Discovery. Circulation. 137: 2315-2317. PMID 29844068 DOI: 10.1161/Circulationaha.117.028194 |
0.36 |
|
| 2017 |
Wang J, Hanada K, Gareri C, Rockman HA. Mechanoactivation of the angiotensin II type 1 receptor induces β-arrestin-biased signaling through Gαi coupling. Journal of Cellular Biochemistry. PMID 29231251 DOI: 10.1002/Jcb.26552 |
0.348 |
|
| 2017 |
Wang J, Hanada K, Staus DP, Makara MA, Dahal GR, Chen Q, Ahles A, Engelhardt S, Rockman HA. Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling. Nature Communications. 8: 1706. PMID 29167435 DOI: 10.1038/S41467-017-01855-Z |
0.34 |
|
| 2017 |
Jean-Charles PY, Yu SM, Abraham D, Kommaddi RP, Mao L, Strachan RT, Zhang ZS, Bowles DE, Brian L, Stiber JA, Jones SN, Koch WJ, Rockman HA, Shenoy SK. Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling. Jci Insight. 2. PMID 28878120 DOI: 10.1172/Jci.Insight.95998 |
0.477 |
|
| 2016 |
Abraham DM, Davis RT, Warren CM, Mao L, Wolska BM, Solaro RJ, Rockman HA. β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911784 DOI: 10.1073/Pnas.1609308113 |
0.414 |
|
| 2016 |
Watson LJ, Alexander KM, Mohan ML, Bowman AL, Mangmool S, Xiao K, Prasad SV, Rockman HA. Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor mediated EGFR transactivation. Cellular Signalling. PMID 27169346 DOI: 10.1016/J.Cellsig.2016.05.006 |
0.313 |
|
| 2016 |
Hodavance SY, Gareri C, Torok RD, Rockman HA. G Protein-Coupled Receptor Biased Agonism. Journal of Cardiovascular Pharmacology. PMID 26751266 DOI: 10.1097/Fjc.0000000000000356 |
0.327 |
|
| 2015 |
Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA. Pacemaker-induced transient asynchrony suppresses heart failure progression. Science Translational Medicine. 7: 319ra207. PMID 26702095 DOI: 10.1126/Scitranslmed.Aad2899 |
0.434 |
|
| 2015 |
Xu W, Barrientos T, Mao L, Rockman HA, Sauve AA, Andrews NC. Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart. Cell Reports. 13: 533-45. PMID 26456827 DOI: 10.1016/J.Celrep.2015.09.023 |
0.405 |
|
| 2015 |
Wisler JW, Harris EM, Raisch M, Mao L, Kim J, Rockman HA, Lefkowitz RJ. The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1516-27. PMID 26371162 DOI: 10.1152/Ajpheart.00291.2015 |
0.338 |
|
| 2015 |
Pironti G, Strachan RT, Abraham D, Mon-Wei Yu S, Chen M, Chen W, Hanada K, Mao L, Watson LJ, Rockman HA. Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors. Circulation. 131: 2120-30. PMID 25995315 DOI: 10.1161/Circulationaha.115.015687 |
0.402 |
|
| 2014 |
Tang W, Strachan RT, Lefkowitz RJ, Rockman HA. Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch. The Journal of Biological Chemistry. 289: 28271-83. PMID 25170081 DOI: 10.1074/Jbc.M114.585067 |
0.328 |
|
| 2014 |
Lee TE, Yu L, Wolf MJ, Rockman HA. Galactokinase is a novel modifier of calcineurin-induced cardiomyopathy in Drosophila. Genetics. 198: 591-603. PMID 25081566 DOI: 10.1534/Genetics.114.166777 |
0.46 |
|
| 2014 |
Ashton JR, Befera N, Clark D, Qi Y, Mao L, Rockman HA, Johnson GA, Badea CT. Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent. Contrast Media & Molecular Imaging. 9: 161-8. PMID 24523061 DOI: 10.1002/Cmmi.1557 |
0.319 |
|
| 2014 |
Santacruz L, Hernandez A, Nienaber J, Mishra R, Pinilla M, Burchette J, Mao L, Rockman HA, Jacobs DO. Normal cardiac function in mice with supraphysiological cardiac creatine levels. American Journal of Physiology. Heart and Circulatory Physiology. 306: H373-81. PMID 24271489 DOI: 10.1152/Ajpheart.00411.2013 |
0.468 |
|
| 2014 |
Wisler J, Harris E, Raisch M, Mao L, Kim J, Rockman H, Lefkowitz R. NON-CANONICAL ANGIOTENSIN II TYPE 1A RECEPTOR-MEDIATED, BETA-ARRESTIN2-DEPENDENT SIGNALING CONTRIBUTES TO THORACIC AORTIC ANEURYSM FORMATION IN A MURINE MODEL OF MARFAN SYNDROME Journal of the American College of Cardiology. 63: A2148. DOI: 10.1016/S0735-1097(14)62151-3 |
0.323 |
|
| 2014 |
Grotegut C, Mao L, Heine RP, Murtha A, Rockman H. 748: Mice lacking G protein-coupled receptor kinase 6 (GRK6) exhibit an enhanced uterine contractile phenotype resulting in stillbirth American Journal of Obstetrics and Gynecology. 210: S367-S368. DOI: 10.1016/J.Ajog.2013.10.781 |
0.368 |
|
| 2013 |
Tang H, Xiao K, Mao L, Rockman HA, Marchuk DA. Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 54: 101-11. PMID 23085512 DOI: 10.1016/J.Yjmcc.2012.10.004 |
0.439 |
|
| 2012 |
Kim KS, Abraham D, Williams B, Violin JD, Mao L, Rockman HA. β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1001-10. PMID 22886417 DOI: 10.1152/Ajpheart.00475.2012 |
0.414 |
|
| 2012 |
Lee CL, Moding EJ, Cuneo KC, Li Y, Sullivan JM, Mao L, Washington I, Jeffords LB, Rodrigues RC, Ma Y, Das S, Kontos CD, Kim Y, Rockman HA, Kirsch DG. p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice. Science Signaling. 5: ra52. PMID 22827996 DOI: 10.1126/Scisignal.2002918 |
0.412 |
|
| 2012 |
Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/Res.0B013E3182582523 |
0.351 |
|
| 2012 |
Casad ME, Yu L, Daniels JP, Wolf MJ, Rockman HA. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Molecular Genetics and Genomics : Mgg. 287: 351-60. PMID 22398840 DOI: 10.1007/S00438-012-0684-X |
0.768 |
|
| 2011 |
Shenoy SK, Rockman HA. Cardiovascular biology: heart fails without pump partner. Nature. 477: 546-7. PMID 21956327 DOI: 10.1038/477546A |
0.434 |
|
| 2011 |
Wolf MJ, Rockman HA. Drosophila, genetic screens, and cardiac function. Circulation Research. 109: 794-806. PMID 21921272 DOI: 10.1161/Circresaha.111.244897 |
0.362 |
|
| 2011 |
Casad ME, Abraham D, Kim IM, Frangakis S, Dong B, Lin N, Wolf MJ, Rockman HA. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Genetics. 189: 861-70. PMID 21890737 DOI: 10.1534/Genetics.111.131482 |
0.745 |
|
| 2011 |
Lin N, Badie N, Yu L, Abraham D, Cheng H, Bursac N, Rockman HA, Wolf MJ. A method to measure myocardial calcium handling in adult Drosophila. Circulation Research. 108: 1306-15. PMID 21493892 DOI: 10.1161/Circresaha.110.238105 |
0.342 |
|
| 2011 |
Grotegut CA, Feng L, Mao L, Heine RP, Murtha AP, Rockman HA. β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration. American Journal of Physiology. Endocrinology and Metabolism. 300: E468-77. PMID 21139074 DOI: 10.1152/Ajpendo.00390.2010 |
0.324 |
|
| 2011 |
Noor N, Patel CB, Rockman HA. Β-arrestin: a signaling molecule and potential therapeutic target for heart failure. Journal of Molecular and Cellular Cardiology. 51: 534-41. PMID 21074538 DOI: 10.1016/J.Yjmcc.2010.11.005 |
0.462 |
|
| 2011 |
Rajagopal S, Kovacs J, Badea C, Johnson GA, Rockman HA, Piantadosi CA, Lefkowitz RJ. BETA-ARRESTINS REGULATE SIGNALING BY BONE MORPHOGENETIC PROTEIN TYPE II RECEPTOR IN PULMONARY ARTERIAL HYPERTENSION Journal of the American College of Cardiology. 57: E2046. DOI: 10.1016/S0735-1097(11)62046-9 |
0.308 |
|
| 2010 |
Patel CB, Noor N, Rockman HA. Functional selectivity in adrenergic and angiotensin signaling systems. Molecular Pharmacology. 78: 983-92. PMID 20855464 DOI: 10.1124/Mol.110.067066 |
0.389 |
|
| 2010 |
Rakesh K, Yoo B, Kim IM, Salazar N, Kim KS, Rockman HA. beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. Science Signaling. 3: ra46. PMID 20530803 DOI: 10.1126/Scisignal.2000769 |
0.392 |
|
| 2010 |
Tilley DG, Nguyen AD, Rockman HA. Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor. Biochemical and Biophysical Research Communications. 396: 921-6. PMID 20460106 DOI: 10.1016/J.Bbrc.2010.05.023 |
0.338 |
|
| 2010 |
Kim BE, Turski ML, Nose Y, Casad M, Rockman HA, Thiele DJ. Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs. Cell Metabolism. 11: 353-63. PMID 20444417 DOI: 10.1016/J.Cmet.2010.04.003 |
0.717 |
|
| 2010 |
Mangmool S, Shukla AK, Rockman HA. beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation. The Journal of Cell Biology. 189: 573-87. PMID 20421423 DOI: 10.1083/Jcb.200911047 |
0.334 |
|
| 2010 |
Bucholz E, Ghaghada K, Qi Y, Mukundan S, Rockman HA, Johnson GA. Cardiovascular phenotyping of the mouse heart using a 4D radial acquisition and liposomal Gd-DTPA-BMA. Magnetic Resonance in Medicine. 63: 979-87. PMID 20373399 DOI: 10.1002/Mrm.22259 |
0.386 |
|
| 2010 |
Kim IM, Wolf MJ, Rockman HA. Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. Circulation Research. 106: 1233-43. PMID 20203305 DOI: 10.1161/Circresaha.109.213785 |
0.36 |
|
| 2009 |
Seth M, Zhang ZS, Mao L, Graham V, Burch J, Stiber J, Tsiokas L, Winn M, Abramowitz J, Rockman HA, Birnbaumer L, Rosenberg P. TRPC1 channels are critical for hypertrophic signaling in the heart. Circulation Research. 105: 1023-30. PMID 19797170 DOI: 10.1161/Circresaha.109.206581 |
0.422 |
|
| 2009 |
Wheeler FC, Tang H, Marks OA, Hadnott TN, Chu PL, Mao L, Rockman HA, Marchuk DA. Tnni3k modifies disease progression in murine models of cardiomyopathy. Plos Genetics. 5: e1000647. PMID 19763165 DOI: 10.1371/Journal.Pgen.1000647 |
0.434 |
|
| 2009 |
Yoo B, Lemaire A, Mangmool S, Wolf MJ, Curcio A, Mao L, Rockman HA. Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1377-86. PMID 19633206 DOI: 10.1152/Ajpheart.00504.2009 |
0.414 |
|
| 2009 |
Pandya K, Porter K, Rockman HA, Smithies O. Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain. European Journal of Heart Failure. 11: 648-52. PMID 19553396 DOI: 10.1093/Eurjhf/Hfp073 |
0.335 |
|
| 2009 |
Tilley DG, Kim IM, Patel PA, Violin JD, Rockman HA. beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling. The Journal of Biological Chemistry. 284: 20375-86. PMID 19509284 DOI: 10.1074/Jbc.M109.005793 |
0.331 |
|
| 2009 |
Fernandez L, Marchuk DA, Moran JL, Beier DR, Rockman HA. An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 296-304. PMID 19387734 DOI: 10.1007/S00335-009-9184-7 |
0.338 |
|
| 2009 |
Lima B, Lam GK, Xie L, Diesen DL, Villamizar N, Nienaber J, Messina E, Bowles D, Kontos CD, Hare JM, Stamler JS, Rockman HA. Endogenous S-nitrosothiols protect against myocardial injury. Proceedings of the National Academy of Sciences of the United States of America. 106: 6297-302. PMID 19325130 DOI: 10.1073/Pnas.0901043106 |
0.338 |
|
| 2009 |
Mehra MR, Rockman HA, Greenberg BH. Highlights of the 2008 Scientific Sessions of the Heart Failure Society of America. Toronto, Ontario, Canada, September 20-23, 2008. Journal of the American College of Cardiology. 53: 514-22. PMID 19195609 DOI: 10.1016/J.Jacc.2008.11.003 |
0.337 |
|
| 2009 |
Patel PA, Tilley DG, Rockman HA. Physiologic and cardiac roles of beta-arrestins. Journal of Molecular and Cellular Cardiology. 46: 300-8. PMID 19103204 DOI: 10.1016/J.Yjmcc.2008.11.015 |
0.358 |
|
| 2008 |
Wolf MJ, Rockman HA. Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discovery Today. Disease Models. 5: 117-123. PMID 19802348 DOI: 10.1016/J.Ddmod.2009.02.002 |
0.45 |
|
| 2008 |
Patel PA, Tilley DG, Rockman HA. Beta-arrestin-mediated signaling in the heart. Circulation Journal : Official Journal of the Japanese Circulation Society. 72: 1725-9. PMID 18838825 DOI: 10.1253/Circj.Cj-08-0734 |
0.419 |
|
| 2008 |
Kim IM, Tilley DG, Chen J, Salazar NC, Whalen EJ, Violin JD, Rockman HA. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14555-60. PMID 18787115 DOI: 10.1073/Pnas.0804745105 |
0.329 |
|
| 2008 |
Pandya K, Cowhig J, Brackhan J, Kim HS, Hagaman J, Rojas M, Carter CW, Mao L, Rockman HA, Maeda N, Smithies O. Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 13063-8. PMID 18755891 DOI: 10.1073/Pnas.0805120105 |
0.416 |
|
| 2008 |
Francois H, Makhanova N, Ruiz P, Ellison J, Mao L, Rockman HA, Coffman TM. A role for the thromboxane receptor in L-NAME hypertension. American Journal of Physiology. Renal Physiology. 295: F1096-102. PMID 18684890 DOI: 10.1152/Ajprenal.00369.2007 |
0.387 |
|
| 2008 |
Ream MA, Chandra R, Peavey M, Ray AM, Roffler-Tarlov S, Kim HG, Wetsel WC, Rockman HA, Chikaraishi DM. High oxygen prevents fetal lethality due to lack of catecholamines. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R942-53. PMID 18635452 DOI: 10.1152/Ajpregu.00860.2007 |
0.353 |
|
| 2008 |
Barki-Harrington L, Rockman HA. Beta-arrestins: multifunctional cellular mediators. Physiology (Bethesda, Md.). 23: 17-22. PMID 18268361 DOI: 10.1152/Physiol.00042.2007 |
0.352 |
|
| 2008 |
Mehra MR, Rockman HA, Greenberg BH. Highlights of the 2007 Scientific Meeting of the Heart Failure Society of America: Washington, DC, September 16-19, 2007. Journal of the American College of Cardiology. 51: 320-7. PMID 18206743 DOI: 10.1016/J.Jacc.2007.11.026 |
0.336 |
|
| 2008 |
Esposito G, Perrino C, Ozaki T, Takaoka H, Defer N, Petretta MP, De Angelis MC, Mao L, Hanoune J, Rockman HA, Chiariello M. Increased myocardial contractility and enhanced exercise function in transgenic mice overexpressing either adenylyl cyclase 5 or 8. Basic Research in Cardiology. 103: 22-30. PMID 18034275 DOI: 10.1007/S00395-007-0688-6 |
0.436 |
|
| 2008 |
Chen J, Rockman HA. Receptor signaling pathways in heart failure: Transgenic mouse models Acute Heart Failure. 89-111. DOI: 10.1007/978-1-84628-782-4_10 |
0.376 |
|
| 2007 |
Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. Plos One. 2: e1051. PMID 17940615 DOI: 10.1371/Journal.Pone.0001051 |
0.343 |
|
| 2007 |
Chin BB, Metzler SD, Lemaire A, Curcio A, Vemulapalli S, Greer KL, Petry NA, Turkington TG, Coleman RE, Rockman H, Jaszczak RJ. Left ventricular functional assessment in mice: feasibility of high spatial and temporal resolution ECG-gated blood pool SPECT. Radiology. 245: 440-8. PMID 17940303 DOI: 10.1148/Radiol.2452061973 |
0.313 |
|
| 2007 |
Allikian MJ, Bhabha G, Dospoy P, Heydemann A, Ryder P, Earley JU, Wolf MJ, Rockman HA, McNally EM. Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. Human Molecular Genetics. 16: 2933-43. PMID 17855453 DOI: 10.1093/Hmg/Ddm254 |
0.341 |
|
| 2007 |
Noma T, Lemaire A, Naga Prasad SV, Barki-Harrington L, Tilley DG, Chen J, Le Corvoisier P, Violin JD, Wei H, Lefkowitz RJ, Rockman HA. Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. The Journal of Clinical Investigation. 117: 2445-58. PMID 17786238 DOI: 10.1172/Jci31901 |
0.39 |
|
| 2007 |
Perrino C, Rockman HA. Reversal of cardiac remodeling by modulation of adrenergic receptors: a new frontier in heart failure. Current Opinion in Cardiology. 22: 443-9. PMID 17762546 DOI: 10.1097/Hco.0B013E3282294D72 |
0.425 |
|
| 2007 |
Badea CT, Hedlund LW, Mackel JF, Mao L, Rockman HA, Johnson GA. Cardiac micro-computed tomography for morphological and functional phenotyping of muscle LIM protein null mice. Molecular Imaging. 6: 261-8. PMID 17711781 DOI: 10.2310/7290.2007.00022 |
0.328 |
|
| 2007 |
Whalen EJ, Foster MW, Matsumoto A, Ozawa K, Violin JD, Que LG, Nelson CD, Benhar M, Keys JR, Rockman HA, Koch WJ, Daaka Y, Lefkowitz RJ, Stamler JS. Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell. 129: 511-22. PMID 17482545 DOI: 10.1016/J.Cell.2007.02.046 |
0.373 |
|
| 2007 |
Salazar NC, Chen J, Rockman HA. Cardiac GPCRs: GPCR signaling in healthy and failing hearts. Biochimica Et Biophysica Acta. 1768: 1006-18. PMID 17376402 DOI: 10.1016/J.Bbamem.2007.02.010 |
0.465 |
|
| 2006 |
Rajagopal K, Whalen EJ, Violin JD, Stiber JA, Rosenberg PB, Premont RT, Coffman TM, Rockman HA, Lefkowitz RJ. Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 16284-9. PMID 17060617 DOI: 10.1073/Pnas.0607583103 |
0.391 |
|
| 2006 |
Donahue MP, Marchuk DA, Rockman HA. Redefining heart failure: the utility of genomics. Journal of the American College of Cardiology. 48: 1289-98. PMID 17010784 DOI: 10.1016/J.Jacc.2006.05.062 |
0.301 |
|
| 2006 |
Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. The Journal of Clinical Investigation. 116: 2218-25. PMID 16878172 DOI: 10.1172/Jci16980 |
0.355 |
|
| 2006 |
Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, et al. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research. 99: 442-50. PMID 16857962 DOI: 10.1161/01.Res.0000237390.92932.37 |
0.421 |
|
| 2006 |
Perrino C, Rockman HA, Chiariello M. Targeted inhibition of phosphoinositide 3-kinase activity as a novel strategy to normalize beta-adrenergic receptor function in heart failure. Vascular Pharmacology. 45: 77-85. PMID 16807128 DOI: 10.1016/J.Vph.2006.01.018 |
0.46 |
|
| 2006 |
Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. The Journal of Clinical Investigation. 116: 1547-60. PMID 16741575 DOI: 10.1172/Jci25397 |
0.46 |
|
| 2006 |
Tilley DG, Rockman HA. Role of beta-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment. Expert Review of Cardiovascular Therapy. 4: 417-32. PMID 16716102 DOI: 10.1586/14779072.4.3.417 |
0.436 |
|
| 2006 |
Curcio A, Noma T, Naga Prasad SV, Wolf MJ, Lemaire A, Perrino C, Mao L, Rockman HA. Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1754-60. PMID 16699071 DOI: 10.1152/Ajpheart.01199.2005 |
0.447 |
|
| 2006 |
Tachibana H, Perrino C, Takaoka H, Davis RJ, Naga Prasad SV, Rockman HA. JNK1 is required to preserve cardiac function in the early response to pressure overload. Biochemical and Biophysical Research Communications. 343: 1060-6. PMID 16579967 DOI: 10.1016/J.Bbrc.2006.03.065 |
0.426 |
|
| 2006 |
Perrino C, Rockman HA. GATA4 and the two sides of gene expression reprogramming. Circulation Research. 98: 715-6. PMID 16574910 DOI: 10.1161/01.Res.0000217593.07196.Af |
0.458 |
|
| 2006 |
Volovyk ZM, Wolf MJ, Prasad SV, Rockman HA. Agonist-stimulated beta-adrenergic receptor internalization requires dynamic cytoskeletal actin turnover. The Journal of Biological Chemistry. 281: 9773-80. PMID 16461348 DOI: 10.1074/Jbc.M511435200 |
0.306 |
|
| 2006 |
Wolf MJ, Amrein H, Izatt JA, Choma MA, Reedy MC, Rockman HA. Drosophila as a model for the identification of genes causing adult human heart disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 1394-9. PMID 16432241 DOI: 10.1073/Pnas.0507359103 |
0.45 |
|
| 2006 |
ROCKMAN H. Heptahelical receptor signaling in heart failure Journal of Molecular and Cellular Cardiology. 41: 1039-1039. DOI: 10.1016/J.Yjmcc.2006.08.020 |
0.42 |
|
| 2005 |
Perrino C, Esposito G, Rockman HA. Defects in cardiomyocyte function: Role of beta-adrenergic receptor dysfunction Panminerva Medica. 47: 143-155. PMID 16462723 |
0.36 |
|
| 2005 |
Rajagopal K, Lefkowitz RJ, Rockman HA. When 7 transmembrane receptors are not G protein-coupled receptors. The Journal of Clinical Investigation. 115: 2971-4. PMID 16276410 DOI: 10.1172/Jci26950 |
0.398 |
|
| 2005 |
Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS, Rockman HA, Fitzgerald GA, Koller BH, Coffman TM. Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metabolism. 2: 201-7. PMID 16154102 DOI: 10.1016/J.Cmet.2005.08.005 |
0.404 |
|
| 2005 |
Naga Prasad SV, Jayatilleke A, Madamanchi A, Rockman HA. Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis. Nature Cell Biology. 7: 785-96. PMID 16094730 DOI: 10.1038/Ncb1278 |
0.309 |
|
| 2005 |
Wheeler FC, Fernandez L, Carlson KM, Wolf MJ, Rockman HA, Marchuk DA. QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 414-23. PMID 16075368 DOI: 10.1007/S00335-005-2468-7 |
0.42 |
|
| 2005 |
Wolf MJ, Tachibana H, Rockman HA. Methods for the detection of altered beta-adrenergic receptor signaling pathways in hypertrophied hearts. Methods in Molecular Medicine. 112: 353-62. PMID 16010029 DOI: 10.1385/1-59259-879-X:353 |
0.48 |
|
| 2005 |
Perrino C, Naga Prasad SV, Patel M, Wolf MJ, Rockman HA. Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression. Journal of the American College of Cardiology. 45: 1862-70. PMID 15936620 DOI: 10.1016/J.Jacc.2005.02.062 |
0.413 |
|
| 2005 |
Perrino C, Naga Prasad SV, Schroder JN, Hata JA, Milano C, Rockman HA. Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex. Circulation. 111: 2579-87. PMID 15897344 DOI: 10.1161/Circulationaha.104.508796 |
0.406 |
|
| 2005 |
Tachibana H, Naga Prasad SV, Lefkowitz RJ, Koch WJ, Rockman HA. Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure. Circulation. 111: 591-7. PMID 15668342 DOI: 10.1161/01.Cir.0000142291.70954.Df |
0.498 |
|
| 2005 |
van den Bosch BJ, van den Burg CM, Schoonderwoerd K, Lindsey PJ, Scholte HR, de Coo RF, van Rooij E, Rockman HA, Doevendans PA, Smeets HJ. Regional absence of mitochondria causing energy depletion in the myocardium of muscle LIM protein knockout mice. Cardiovascular Research. 65: 411-8. PMID 15639480 DOI: 10.1016/J.Cardiores.2004.10.025 |
0.404 |
|
| 2005 |
Nassar R, Malouf NN, Mao L, Rockman HA, Oakeley AE, Frye JR, Herlong JR, Sanders SP, Anderson PA. cTnT1, a cardiac troponin T isoform, decreases myofilament tension and affects the left ventricular pressure waveform. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1147-56. PMID 15513965 DOI: 10.1152/Ajpheart.00140.2004 |
0.417 |
|
| 2005 |
Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. The Journal of Biological Chemistry. 280: 669-76. PMID 15492008 DOI: 10.1074/Jbc.M406690200 |
0.449 |
|
| 2005 |
Skavdahl M, Steenbergen C, Clark J, Myers P, Demianenko T, Mao L, Rockman HA, Korach KS, Murphy E. Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 288: H469-76. PMID 15374829 DOI: 10.1152/Ajpheart.00723.2004 |
0.359 |
|
| 2004 |
Kedar V, McDonough H, Arya R, Li HH, Rockman HA, Patterson C. Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I. Proceedings of the National Academy of Sciences of the United States of America. 101: 18135-40. PMID 15601779 DOI: 10.1073/Pnas.0404341102 |
0.401 |
|
| 2004 |
Barki-Harrington L, Perrino C, Rockman HA. Network integration of the adrenergic system in cardiac hypertrophy. Cardiovascular Research. 63: 391-402. PMID 15276464 DOI: 10.1016/J.Cardiores.2004.03.011 |
0.487 |
|
| 2004 |
Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC. Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circulation Research. 95: 506-14. PMID 15256482 DOI: 10.1161/01.Res.0000139436.89654.C8 |
0.402 |
|
| 2004 |
Tong H, Rockman HA, Koch WJ, Steenbergen C, Murphy E. G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning. Circulation Research. 94: 1133-41. PMID 15031261 DOI: 10.1161/01.Res.0000126048.32383.6B |
0.411 |
|
| 2004 |
Caron KM, James LR, Kim HS, Knowles J, Uhlir R, Mao L, Hagaman JR, Cascio W, Rockman H, Smithies O. Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proceedings of the National Academy of Sciences of the United States of America. 101: 3106-11. PMID 14978280 DOI: 10.1073/Pnas.0307333101 |
0.455 |
|
| 2004 |
Francois H, Athirakul K, Mao L, Rockman H, Coffman TM. Role for Thromboxane Receptors in Angiotensin-II-Induced Hypertension Hypertension. 43: 364-369. PMID 14718360 DOI: 10.1161/01.Hyp.0000112225.27560.24 |
0.375 |
|
| 2004 |
Lemaire A, Rockman HA. The role of G-protein-coupled receptors in heart failure Drug Discovery Today: Disease Mechanisms. 1: 37-43. DOI: 10.1016/J.Ddmec.2004.08.013 |
0.423 |
|
| 2003 |
Nienaber JJ, Tachibana H, Naga Prasad SV, Esposito G, Wu D, Mao L, Rockman HA. Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure. The Journal of Clinical Investigation. 112: 1067-79. PMID 14523044 DOI: 10.1172/Jci18213 |
0.501 |
|
| 2003 |
Le Corvoisier P, Park HY, Carlson KM, Marchuk DA, Rockman HA. Multiple quantitative trait loci modify the heart failure phenotype in murine cardiomyopathy. Human Molecular Genetics. 12: 3097-107. PMID 14519689 DOI: 10.1093/Hmg/Ddg333 |
0.431 |
|
| 2003 |
Barki-Harrington L, Luttrell LM, Rockman HA. Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation. 108: 1611-8. PMID 12963634 DOI: 10.1161/01.Cir.0000092166.30360.78 |
0.328 |
|
| 2003 |
Keys JR, Greene EA, Cooper CJ, Naga Prasad SV, Rockman HA, Koch WJ. Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2201-11. PMID 12869383 DOI: 10.1152/Ajpheart.00112.2003 |
0.386 |
|
| 2003 |
Blaxall BC, Spang R, Rockman HA, Koch WJ. Differential myocardial gene expression in the development and rescue of murine heart failure. Physiological Genomics. 15: 105-14. PMID 12865503 DOI: 10.1152/Physiolgenomics.00087.2003 |
0.467 |
|
| 2003 |
Naga Prasad SV, Perrino C, Rockman HA. Role of phosphoinositide 3-kinase in cardiac function and heart failure. Trends in Cardiovascular Medicine. 13: 206-12. PMID 12837584 DOI: 10.1016/S1050-1738(03)00080-X |
0.452 |
|
| 2003 |
Rapacciuolo A, Suvarna S, Barki-Harrington L, Luttrell LM, Cong M, Lefkowitz RJ, Rockman HA. Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. The Journal of Biological Chemistry. 278: 35403-11. PMID 12821660 DOI: 10.1074/Jbc.M305675200 |
0.315 |
|
| 2003 |
Most P, Remppis A, Pleger ST, Löffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H, Karczewski P, Mao L, Rockman HA, Duncan SJ, Katus HA, et al. Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. The Journal of Biological Chemistry. 278: 33809-17. PMID 12777394 DOI: 10.1074/Jbc.M301788200 |
0.459 |
|
| 2003 |
Colomer JM, Mao L, Rockman HA, Means AR. Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo. Molecular Endocrinology (Baltimore, Md.). 17: 183-92. PMID 12554746 DOI: 10.1210/Me.2002-0350 |
0.416 |
|
| 2003 |
Barki-Harrington L, Rockman HA. Sensing heart stress. Nature Medicine. 9: 19-20. PMID 12514714 DOI: 10.1038/Nm0103-19 |
0.408 |
|
| 2003 |
Le Corvoisier P, Park H, Carlson KM, Marchuk DA, Rockman HA. Two quantitative trait loci on chromosomes 4 and 18 modify mice survival in a model of heart failure Journal of Cardiac Failure. 9: S39. DOI: 10.1016/S1071-9164(03)00486-X |
0.371 |
|
| 2002 |
Naga Prasad SV, Nienaber J, Rockman HA. G-protein-coupled receptor function in heart failure Cold Spring Harbor Symposia On Quantitative Biology. 67: 439-444. PMID 12858569 DOI: 10.1101/Sqb.2002.67.439 |
0.411 |
|
| 2002 |
Esposito G, Rapacciuolo A, Naga Prasad SV, Rockman HA. Cardiac hypertrophy: role of G protein-coupled receptors. Journal of Cardiac Failure. 8: S409-14. PMID 12555153 DOI: 10.1054/Jcaf.2002.129283 |
0.48 |
|
| 2002 |
Naga Prasad SV, Laporte SA, Chamberlain D, Caron MG, Barak L, Rockman HA. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. The Journal of Cell Biology. 158: 563-75. PMID 12163475 DOI: 10.1083/Jcb.200202113 |
0.339 |
|
| 2002 |
Feldman DS, Zamah AM, Pierce KL, Miller WE, Kelly F, Rapacciuolo A, Rockman HA, Koch WJ, Luttrell LM. Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. The Journal of Biological Chemistry. 277: 28631-40. PMID 12036966 DOI: 10.1074/Jbc.M204753200 |
0.345 |
|
| 2002 |
Takaoka H, Esposito G, Mao L, Suga H, Rockman HA. Heart size-independent analysis of myocardial function in murine pressure overload hypertrophy American Journal of Physiology - Heart and Circulatory Physiology. 282. PMID 12003828 DOI: 10.1152/Ajpheart.00759.2001 |
0.402 |
|
| 2002 |
Suzuki M, Carlson KM, Marchuk DA, Rockman HA. Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy. Circulation. 105: 1824-9. PMID 11956126 DOI: 10.1161/01.Cir.0000014926.32463.89 |
0.347 |
|
| 2002 |
Eckhart AD, Ozaki T, Tevaearai H, Rockman HA, Koch WJ. Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates β-adrenergic receptor signaling and increases resting blood pressure Molecular Pharmacology. 61: 749-758. PMID 11901213 DOI: 10.1124/Mol.61.4.749 |
0.417 |
|
| 2002 |
Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 415: 206-12. PMID 11805844 DOI: 10.1038/415206A |
0.44 |
|
| 2002 |
Esposito G, Rapacciuolo A, Naga Prasad SV, Takaoka H, Thomas SA, Koch WJ, Rockman HA. Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation. 105: 85-92. PMID 11772881 DOI: 10.1161/Hc0102.101365 |
0.39 |
|
| 2001 |
Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ, Rockman HA. Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice. Circulation. 104: 2485-91. PMID 11705829 DOI: 10.1161/Hc4501.098933 |
0.418 |
|
| 2001 |
Rapacciuolo A, Esposito G, Naga Prasad SV, Rockman HA. G protein-coupled receptor signalling in in vivo cardiac overload Acta Physiologica Scandinavica. 173: 51-57. PMID 11678726 DOI: 10.1046/J.1365-201X.2001.00884.X |
0.483 |
|
| 2001 |
Naga Prasad SV, Nienaber J, Rockman HA. β-Adrenergic axis and heart disease Trends in Genetics. 17. PMID 11585676 DOI: 10.1016/S0168-9525(01)02487-8 |
0.428 |
|
| 2001 |
Rapacciuolo A, Esposito G, Caron K, Mao L, Thomas SA, Rockman HA. Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy. Journal of the American College of Cardiology. 38: 876-82. PMID 11527648 DOI: 10.1016/S0735-1097(01)01433-4 |
0.432 |
|
| 2001 |
Iaccarino G, Keys JR, Rapacciuolo A, Shotwell KF, Lefkowitz RJ, Rockman HA, Koch WJ. Regulation of myocardial betaARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing alpha1B-adrenergic receptors. Journal of the American College of Cardiology. 38: 534-40. PMID 11499749 DOI: 10.1016/S0735-1097(01)01396-1 |
0.464 |
|
| 2001 |
Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quinones LE, Santana LF. Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. The Journal of Biological Chemistry. 276: 28197-203. PMID 11369778 DOI: 10.1074/Jbc.M102548200 |
0.373 |
|
| 2001 |
Harding VB, Jones LR, Lefkowitz RJ, Koch WJ, Rockman HA. Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proceedings of the National Academy of Sciences of the United States of America. 98: 5809-14. PMID 11331748 DOI: 10.1073/Pnas.091102398 |
0.471 |
|
| 2001 |
Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of Clinical Investigation. 107: 975-84. PMID 11306601 DOI: 10.1172/Jci11273 |
0.459 |
|
| 2001 |
Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1: A role in receptor sequestration Journal of Biological Chemistry. 276: 18953-18959. PMID 11259422 DOI: 10.1074/Jbc.M102376200 |
0.336 |
|
| 2001 |
Esposito G, Naga Prasad SV, Rapacciuolo A, Mao L, Koch WJ, Rockman HA. Cardiac overexpression of a Gq inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activity in in vivo pressure overload Circulation. 103: 1453-1458. PMID 11245652 DOI: 10.1161/01.Cir.103.10.1453 |
0.432 |
|
| 2000 |
Manning BS, Shotwell K, Mao L, Rockman HA, Koch WJ. Physiological induction of a β-adrenergic receptor kinase inhibitor transgene preserves β-adrenergic responsiveness in pressure-overload cardiac hypertrophy Circulation. 102: 2751-2757. PMID 11094043 DOI: 10.1161/01.Cir.102.22.2751 |
0.496 |
|
| 2000 |
Esposito G, Santana LF, Dilly K, Cruz JD, Mao L, Lederer WJ, Rockman HA. Cellular and functional defects in a mouse model of heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3101-12. PMID 11087268 DOI: 10.1152/Ajpheart.2000.279.6.H3101 |
0.459 |
|
| 2000 |
Brewis N, Ohst K, Fields K, Rapacciuolo A, Chou D, Bloor C, Dillmann W, Rockman H, Walter G. Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A. American Journal of Physiology. Heart and Circulatory Physiology. 279: H1307-18. PMID 10993798 DOI: 10.1152/Ajpheart.2000.279.3.H1307 |
0.417 |
|
| 2000 |
Koch WJ, Lefkowitz RJ, Rockman HA. Functional consequences of altering myocardial adrenergic receptor signaling. Annual Review of Physiology. 62: 237-60. PMID 10845091 DOI: 10.1146/Annurev.Physiol.62.1.237 |
0.49 |
|
| 2000 |
Lipskaia L, Defer N, Esposito G, Hajar I, Garel MC, Rockman HA, Hanoune J. Enhanced cardiac function in transgenic mice expressing a Ca2+- stimulated adenylyl cyclase Circulation Research. 86: 795-801. PMID 10764414 DOI: 10.1161/01.Res.86.7.795 |
0.465 |
|
| 2000 |
Lefkowitz RJ, Rockman HA, Koch WJ. Catecholamines, cardiac beta-adrenergic receptors, and heart failure. Circulation. 101: 1634-7. PMID 10758041 DOI: 10.1161/01.Cir.101.14.1634 |
0.455 |
|
| 2000 |
Naga Prasad SV, Esposito G, Mao L, Koch WJ, Rockman HA. Gβγ-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy Journal of Biological Chemistry. 275: 4693-4698. PMID 10671499 DOI: 10.1074/Jbc.275.7.4693 |
0.403 |
|
| 1999 |
Choi DJ, Rockman HA. β-adrenergic receptor desensitization in cardiac hypertrophy and heart failure Cell Biochemistry and Biophysics. 31: 321-329. PMID 10736754 DOI: 10.1007/Bf02738246 |
0.471 |
|
| 1999 |
Koch WJ, Rockman HA. Exploring the role of the β-adrenergic receptor kinase in cardiac disease using gene-targeted mice Trends in Cardiovascular Medicine. 9: 77-81. PMID 10578521 DOI: 10.1016/S1050-1738(99)00009-2 |
0.502 |
|
| 1999 |
Akhter SA, Eckhart AD, Rockman HA, Shotwell K, Lefkowitz RJ, Koch WJ. In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. Circulation. 100: 648-53. PMID 10441103 DOI: 10.1161/01.Cir.100.6.648 |
0.485 |
|
| 1999 |
Cho MC, Rapacciuolo A, Koch WJ, Kobayashi Y, Jones LR, Rockman HA. Defective β-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression Journal of Biological Chemistry. 274: 22251-22256. PMID 10428792 DOI: 10.1074/Jbc.274.32.22251 |
0.439 |
|
| 1999 |
Cho MC, Rao M, Koch WJ, Thomas SA, Palmiter RD, Rockman HA. Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine. Circulation. 99: 2702-7. PMID 10338466 DOI: 10.1161/01.Cir.99.20.2702 |
0.484 |
|
| 1999 |
Rapacciuolo A, Rockman HA. Role of β-adrenoceptor desensitization in heart failure Cardiovascular Drug Reviews. 17: 384-394. DOI: 10.1111/J.1527-3466.1999.Tb00027.X |
0.458 |
|
| 1998 |
Tanaka N, Ryoke T, Hongo M, Mao L, Rockman HA, Clark RG, Ross J. Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. American Journal of Physiology. Heart and Circulatory Physiology. 275: H393-H399. PMID 29591565 DOI: 10.1152/Ajpheart.1998.275.2.H393 |
0.399 |
|
| 1998 |
Iaccarino G, Rockman HA, Shotwell KF, Tomhave ED, Koch WJ. Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs. American Journal of Physiology. Heart and Circulatory Physiology. 275: H1298-H1306. PMID 29586850 DOI: 10.1152/ajpheart.1998.275.4.H1298 |
0.353 |
|
| 1998 |
Neumann J, Boknik P, DePaoli-Roach AA, Field LJ, Rockman HA, Kobayashi YM, Kelley JS, Jones LR. Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility Journal of Molecular and Cellular Cardiology. 30: 1991-2002. PMID 9799653 DOI: 10.1006/Jmcc.1998.0760 |
0.36 |
|
| 1998 |
Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. The Journal of Biological Chemistry. 273: 18180-4. PMID 9660778 DOI: 10.1074/Jbc.273.29.18180 |
0.474 |
|
| 1998 |
Rockman HA, Chien KR, Choi DJ, Iaccarino G, Hunter JJ, Ross J, Lefkowitz RJ, Koch WJ. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 7000-5. PMID 9618528 DOI: 10.1073/Pnas.95.12.7000 |
0.516 |
|
| 1998 |
Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science (New York, N.Y.). 280: 574-7. PMID 9554846 DOI: 10.1126/Science.280.5363.574 |
0.444 |
|
| 1998 |
Iaccarino G, Rockman HA, Shotwell KF, Tomhave ED, Koch WJ. Myocardial overexpression of GRK3 in transgenic mice: Evidence for in vivo selectivity of GRKs American Journal of Physiology - Heart and Circulatory Physiology. 44. DOI: 10.1152/Ajpheart.1998.275.4.H1298 |
0.458 |
|
| 1997 |
Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proceedings of the National Academy of Sciences of the United States of America. 94: 14730-5. PMID 9405681 DOI: 10.1073/Pnas.94.26.14730 |
0.449 |
|
| 1997 |
Rockman HA. Uncoupling of G-Protein coupled receptors In Vivo: Insights from transgenic mice Advances in Experimental Medicine and Biology. 430: 67-72. PMID 9330719 DOI: 10.1007/978-1-4615-5959-7_6 |
0.462 |
|
| 1997 |
Akhter SA, Milano CA, Shotwell KF, Cho MC, Rockman HA, Lefkowitz RJ, Koch WJ. Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling. The Journal of Biological Chemistry. 272: 21253-9. PMID 9261135 DOI: 10.1074/Jbc.272.34.21253 |
0.463 |
|
| 1997 |
He H, Giordano FJ, Hilal-Dandan R, Choi DJ, Rockman HA, McDonough PM, Bluhm WF, Meyer M, Sayen MR, Swanson E, Dillmann WH. Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation Journal of Clinical Investigation. 100: 380-389. PMID 9218515 DOI: 10.1172/Jci119544 |
0.399 |
|
| 1997 |
Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of β-adrenergic receptor desensitization in cardiac hypertrophy is increased β-adrenergic receptor kinase Journal of Biological Chemistry. 272: 17223-17229. PMID 9202046 DOI: 10.1074/Jbc.272.27.17223 |
0.477 |
|
| 1997 |
Sack MN, Disch DL, Rockman HA, Kelly DP. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program Proceedings of the National Academy of Sciences of the United States of America. 94: 6438-6443. PMID 9177236 DOI: 10.1073/Pnas.94.12.6438 |
0.424 |
|
| 1997 |
Rockman HA, Koch WJ, Lefkowitz RJ. Cardiac function in genetically engineered mice with altered adrenergic receptor signaling. The American Journal of Physiology. 272: H1553-9. PMID 9139936 DOI: 10.1152/Ajpheart.1997.272.4.H1553 |
0.486 |
|
| 1997 |
Ryu KH, Tanaka N, Dalton N, Mao L, Rockman HA, Milano CA, Ross J. Force-frequency relations in the failing rabbit heart and responses to adrenergic stimulation Journal of Cardiac Failure. 3: 27-39. PMID 9110253 DOI: 10.1016/S1071-9164(97)90006-3 |
0.446 |
|
| 1997 |
Samama P, Bond RA, Rockman HA, Milano CA, Lefkowitz RJ. Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 137-41. PMID 8990174 DOI: 10.1073/Pnas.94.1.137 |
0.433 |
|
| 1997 |
Cho MC, Koch WJ, Rockman HA. Gene therapy for chronic heart failure Acc Current Journal Review. 6: 56-58. DOI: 10.1016/S1062-1458(97)83289-8 |
0.354 |
|
| 1997 |
Choi DJ, Koch WJ, Rockman HA. Cardiac hypertrophy is associated with increased β-adrenergic receptor kinase (βARK) Faseb Journal. 11. |
0.354 |
|
| 1996 |
Lembo G, Rockman HA, Hunter JJ, Steinmetz H, Koch WJ, Ma L, Prinz MP, Ross J, Chien KR, Powell-Braxton L. Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency Journal of Clinical Investigation. 98: 2648-2655. PMID 8958230 DOI: 10.1172/Jci119086 |
0.379 |
|
| 1996 |
Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 12974-9. PMID 8917529 DOI: 10.1073/Pnas.93.23.12974 |
0.412 |
|
| 1996 |
Rockman HA, Koch WJ, Milano CA, Lefkowitz RJ. Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice. Journal of Molecular Medicine (Berlin, Germany). 74: 489-95. PMID 8892053 DOI: 10.1007/Bf00204974 |
0.477 |
|
| 1996 |
Rockman HA, Choi DJ, Rahman NU, Akhter SA, Lefkowitz RJ, Koch WJ. Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 9954-9. PMID 8790438 DOI: 10.1073/Pnas.93.18.9954 |
0.431 |
|
| 1996 |
Tanaka N, Dalton N, Mao L, Rockman HA, Peterson KL, Gottshall KR, Hunter JJ, Chien KR, Ross J. Transthoracic echocardiography in models of cardiac disease in the mouse Circulation. 94: 1109-1117. PMID 8790053 DOI: 10.1161/01.Cir.94.5.1109 |
0.431 |
|
| 1996 |
Rockman HA, Hamilton RA, Jones LR, Milano CA, Mao L, Lefkowitz RJ. Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. The Journal of Clinical Investigation. 97: 1618-23. PMID 8601626 DOI: 10.1172/Jci118587 |
0.403 |
|
| 1996 |
Ben-Yehuda O, Rockman HA. Regulation of myocardial contractility: Insights from transgenic mice Trends in Cardiovascular Medicine. 6: 95-99. DOI: 10.1016/1050-1738(96)00010-2 |
0.438 |
|
| 1995 |
Bond RA, Leff P, Johnson TD, Milano CA, Rockman HA, McMinn TR, Apparsundaram S, Hyek MF, Kenakin TP, Allen LF, Lefkowitz RJ. Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor Nature. 374: 272-276. PMID 7885448 DOI: 10.1038/374272A0 |
0.313 |
|
| 1995 |
Milano CA, Allen LF, Dolber PC, Johnson TD, Rockman HA, Bond RA, Lefkowitz RJ. Marked enhancement in myocardial function resulting from overexpression of a human β-adrenergic receptor gene The Journal of Thoracic and Cardiovascular Surgery. 109: 236-241. PMID 7853876 DOI: 10.1016/S0022-5223(95)70384-5 |
0.476 |
|
| 1995 |
Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science (New York, N.Y.). 268: 1350-3. PMID 7761854 DOI: 10.1126/Science.7761854 |
0.405 |
|
| 1995 |
Knowlton KU, Rockman HA, Itani M, Vovan A, Seidman CE, Chien KR. Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium Journal of Clinical Investigation. 96: 1311-1318. PMID 7657806 DOI: 10.1172/Jci118166 |
0.402 |
|
| 1995 |
Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Cardiac function in mice overexpressing the β-adrenergic receptor kinase or a βARK inhibitor Circulation. 92: 277. PMID 7634434 |
0.311 |
|
| 1995 |
Lin MC, Rockman HA, Chien KR. Heart and lung disease in engineered mice Nature Medicine. 1: 749-751. PMID 7585174 DOI: 10.1038/Nm0895-749 |
0.315 |
|
| 1995 |
Hunter JJ, Tanaka N, Rockman HA, Ross J, Chien KR. Ventricular expression of a mlc-2v-ras fusion gene induces cardiac hypertrophy selective diastolic dysfunction in transgenic mice Journal of Biological Chemistry. 270: 23173-23178. PMID 7559464 DOI: 10.1074/Jbc.270.39.23173 |
0.464 |
|
| 1995 |
Rockman HA, Hamilton R, Milano CA, Mao L, Lefkowitz RJ, Koch WJ. 718-3 Cardiac Overexpression of βARK in Transgenic Mice Inhibits Isoproterenol Stimulated Contractility In Vivo Journal of the American College of Cardiology. 25: 91A. DOI: 10.1016/0735-1097(95)91830-Q |
0.432 |
|
| 1994 |
Ono S, Bhargava V, Mao L, Hagan G, Rockman HA, Ross J. In vivo assessment of left ventricular remodelling after myocardial infarction by digital video contrast angiography in the rat Cardiovascular Research. 28: 349-357. PMID 8174155 DOI: 10.1093/Cvr/28.3.349 |
0.322 |
|
| 1994 |
Omens JH, Rockman HA, Covell JW. Passive ventricular mechanics in tight-skin mice American Journal of Physiology - Heart and Circulatory Physiology. 266: H1169-H1176. PMID 8160820 DOI: 10.1152/Ajpheart.1994.266.3.H1169 |
0.324 |
|
| 1994 |
Milano CA, Allen LF, Rockman HA, Dolber PC, McMinn TR, Chien KR, Johnson TD, Bond RA, Lefkowitz RJ. Enhanced myocardial function in transgenic mice overexpressing the β2-adrenergic receptor Science. 264: 582-586. PMID 8160017 DOI: 10.1126/Science.8160017 |
0.49 |
|
| 1994 |
Rockman HA, Ono S, Ross RS, Jones LR, Karimi M, Bhargava V, Ross J, Chien KR. Molecular and physiological alterations in murine ventricular dysfunction Proceedings of the National Academy of Sciences of the United States of America. 91: 2694-2698. PMID 8146176 DOI: 10.1073/Pnas.91.7.2694 |
0.381 |
|
| 1994 |
Rockman HA, Wachhorst SP, Mao L, Ross J. ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice American Journal of Physiology - Heart and Circulatory Physiology. 266. PMID 8024008 DOI: 10.1152/Ajpheart.1994.266.6.H2468 |
0.395 |
|
| 1994 |
Milano CA, Dolber PC, Rockman HA, Bond RA, Venable ME, Allen LF, Lefkowitz RJ. Myocardial expression of a constitutively active α1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy Proceedings of the National Academy of Sciences of the United States of America. 91: 10109-10113. PMID 7937846 DOI: 10.1073/Pnas.91.21.10109 |
0.471 |
|
| 1993 |
Rockman HA, Knowlton KU, Ross J, Chien KR. In vivo murine cardiac hypertrophy: A novel model to identify genetic signaling mechanisms that activate an adaptive physiological response Circulation. 87. |
0.381 |
|
| 1992 |
Kambayashi M, Miura T, Oh BH, Rockman HA, Murata K, Ross J. Enhancement of the force-frequency effect on myocardial contractility by adrenergic stimulation in conscious dogs Circulation. 86: 572-580. PMID 1353420 DOI: 10.1161/01.Cir.86.2.572 |
0.344 |
|
| 1991 |
Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J, Chien KR. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 88: 8277-81. PMID 1832775 DOI: 10.1073/Pnas.88.18.8277 |
0.398 |
|
| 1991 |
Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J. Corrections and Retraction: Segregation of Atrial-Specific and Inducible Expression of an Atrial Natriuretic Factor Transgene in an In vivo Murine Model of Cardiac Hypertrophy Proceedings of the National Academy of Sciences of the United States of America. 88: 9907. DOI: 10.1073/Pnas.88.21.9907A |
0.379 |
|
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