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Daryl E. Klein, Ph.D. - Publications

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Medical Biophysics, Molecular Biology, Biochemistry
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, ... ... Klein DE, et al. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature. 600: 148-152. PMID 34819665 DOI: 10.1038/s41586-021-04141-7  0.697
2020 Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA. Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics. Science Signaling. 13. PMID 32817373 DOI: 10.1126/Scisignal.Aaz5267  0.591
2017 Klein DE. A ligand divided: antagonist, agonist and analog control. The Biochemical Journal. 474: 3087-3088. PMID 28860336 DOI: 10.1042/Bcj20170495  0.427
2017 Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Abdulhay NJ, King DS, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, ... ... Klein DE, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 168: 1053-1064.e15. PMID 28283061 DOI: 10.1016/J.Cell.2017.02.026  0.386
2016 Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, Ozdemir M, Garcia C, ... ... Klein D, et al. Discovery of the First Pathogenic Human EPO Mutation Provides Mechanistic Insight into Cytokine Signaling Blood. 128: 331-331. DOI: 10.1182/Blood.V128.22.331.331  0.365
2015 Jenni S, Goyal Y, von Grotthuss M, Shvartsman SY, Klein DE. Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Molecular Cell. 60: 941-52. PMID 26698662 DOI: 10.1016/J.Molcel.2015.10.026  0.445
2015 Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Correction: Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 4. PMID 25984968 DOI: 10.7554/Elife.08656  0.717
2014 Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 3: e04389. PMID 25479384 DOI: 10.7554/Elife.04389  0.72
2014 Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Author response: Sequential conformational rearrangements in flavivirus membrane fusion Elife. DOI: 10.7554/Elife.04389.017  0.714
2013 Klein DE, Choi JL, Harrison SC. Structure of a dengue virus envelope protein late-stage fusion intermediate. Journal of Virology. 87: 2287-93. PMID 23236058 DOI: 10.1128/Jvi.02957-12  0.524
2010 Alvarado D, Klein DE, Lemmon MA. Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell. 142: 568-79. PMID 20723758 DOI: 10.1016/J.Cell.2010.07.015  0.641
2009 Alvarado D, Klein DE, Lemmon MA. ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor. Nature. 461: 287-91. PMID 19718021 DOI: 10.1038/Nature08297  0.622
2008 Klein DE, Stayrook SE, Shi F, Narayan K, Lemmon MA. Structural basis for EGFR ligand sequestration by Argos. Nature. 453: 1271-5. PMID 18500331 DOI: 10.1038/Nature06978  0.715
2005 Reeves GT, Kalifa R, Klein DE, Lemmon MA, Shvartsman SY. Computational analysis of EGFR inhibition by Argos. Developmental Biology. 284: 523-35. PMID 15982648 DOI: 10.1016/J.Ydbio.2005.05.013  0.584
2004 Klein DE, Nappi VM, Reeves GT, Shvartsman SY, Lemmon MA. Argos inhibits epidermal growth factor receptor signalling by ligand sequestration. Nature. 430: 1040-4. PMID 15329724 DOI: 10.1038/Nature02840  0.625
2001 Sankaran VG, Klein DE, Sachdeva MM, Lemmon MA. High-affinity binding of a FYVE domain to phosphatidylinositol 3-phosphate requires intact phospholipid but not FYVE domain oligomerization. Biochemistry. 40: 8581-7. PMID 11456498 DOI: 10.1021/Bi010425D  0.602
1998 Kavran JM, Klein DE, Lee A, Falasca M, Isakoff SJ, Skolnik EY, Lemmon MA. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains. The Journal of Biological Chemistry. 273: 30497-508. PMID 9804818 DOI: 10.1074/Jbc.273.46.30497  0.597
1998 Klein DE, Lee A, Frank DW, Marks MS, Lemmon MA. The pleckstrin homology domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding. The Journal of Biological Chemistry. 273: 27725-33. PMID 9765310 DOI: 10.1074/Jbc.273.42.27725  0.608
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