| Year |
Citation |
Score |
| 2022 |
Gupta A, Martin-Rufino JD, Jones TR, Subramanian V, Qiu X, Grody EI, Bloemendal A, Weng C, Niu SY, Min KH, Mehta A, Zhang K, Siraj L, Al' Khafaji A, Sankaran VG, ... ... Lander ES, et al. Inferring gene regulation from stochastic transcriptional variation across single cells at steady state. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207392119. PMID 35969771 DOI: 10.1073/pnas.2207392119 |
0.453 |
|
| 2021 |
Nasser J, Bergman DT, Fulco CP, Guckelberger P, Doughty BR, Patwardhan TA, Jones TR, Nguyen TH, Ulirsch JC, Lekschas F, Mualim K, Natri HM, Weeks EM, Munson G, Kane M, ... ... Lander ES, et al. Genome-wide enhancer maps link risk variants to disease genes. Nature. PMID 33828297 DOI: 10.1038/s41586-021-03446-x |
0.506 |
|
| 2021 |
Collins RL, Brand H, Karczewski KJ, Zhao X, Alföldi J, Francioli LC, Khera AV, Lowther C, Gauthier LD, Wang H, Watts NA, Solomonson M, O'Donnell-Luria A, Baumann A, Munshi R, ... ... Lander E, et al. Author Correction: A structural variation reference for medical and population genetics. Nature. PMID 33536627 DOI: 10.1038/s41586-020-03176-6 |
0.331 |
|
| 2021 |
Sinnott-Armstrong N, Sousa IS, Laber S, Rendina-Ruedy E, Nitter Dankel SE, Ferreira T, Mellgren G, Karasik D, Rivas M, Pritchard J, Guntur AR, Cox RD, Lindgren CM, Hauner H, Sallari R, ... ... Lander ES, et al. A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. Cell Metabolism. PMID 33513366 DOI: 10.1016/j.cmet.2021.01.001 |
0.796 |
|
| 2020 |
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, ... ... Lander ES, et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33057201 DOI: 10.1038/s41586-020-2819-2 |
0.344 |
|
| 2020 |
Collins RL, Brand H, Karczewski KJ, Zhao X, Alföldi J, Francioli LC, Khera AV, Lowther C, Gauthier LD, Wang H, Watts NA, Solomonson M, O'Donnell-Luria A, Baumann A, Munshi R, ... ... Lander E, et al. A structural variation reference for medical and population genetics. Nature. 581: 444-451. PMID 32461652 DOI: 10.1038/S41586-020-2287-8 |
0.582 |
|
| 2020 |
Abel HJ, Larson DE, Regier AA, Chiang C, Das I, Kanchi KL, Layer RM, Neale BM, Salerno WJ, Reeves C, Buyske S, Matise TC, Muzny DM, Zody MC, ... Lander ES, et al. Mapping and characterization of structural variation in 17,795 human genomes. Nature. PMID 32460305 DOI: 10.1038/s41586-020-2371-0 |
0.362 |
|
| 2020 |
Vallabh SM, Minikel EV, Schreiber SL, Lander ES. Towards a treatment for genetic prion disease: trials and biomarkers. The Lancet. Neurology. 19: 361-368. PMID 32199098 DOI: 10.1016/S1474-4422(19)30403-X |
0.348 |
|
| 2019 |
Fulco CP, Nasser J, Jones TR, Munson G, Bergman DT, Subramanian V, Grossman SR, Anyoha R, Doughty BR, Patwardhan TA, Nguyen TH, Kane M, Perez EM, Durand NC, Lareau CA, ... ... Lander ES, et al. Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations. Nature Genetics. 51: 1664-1669. PMID 31784727 DOI: 10.1038/s41588-019-0538-0 |
0.318 |
|
| 2019 |
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Lander ES, et al. Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 31636380 DOI: 10.1038/s41380-019-0529-7 |
0.403 |
|
| 2018 |
Khera AV, Chaffin M, Zekavat SM, Collins RL, Roselli C, Natarajan P, Lichtman JH, D'Onofrio G, Mattera JA, Dreyer RP, Spertus JA, Taylor KD, Psaty BM, Rich SS, Post WS, ... ... Lander E, et al. Whole Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized with Early-Onset Myocardial Infarction. Circulation. PMID 30586733 DOI: 10.1161/Circulationaha.118.035658 |
0.393 |
|
| 2018 |
Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, Khera AV, Zhou W, Bloom JM, Engreitz JM, Ernst J, O'Connell JR, Ruotsalainen SE, Alver M, Manichaikul A, ... ... Lander ES, et al. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nature Communications. 9: 3391. PMID 30140000 DOI: 10.1038/S41467-018-05747-8 |
0.704 |
|
| 2018 |
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Lander ES, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7 |
0.464 |
|
| 2018 |
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Lander ES, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2 |
0.751 |
|
| 2018 |
Mullane SA, Painter C, Dunphy M, Anastasio E, Simoncelli T, Zarrelli K, Philippakis A, McKay RR, Choueiri TK, Golub T, Lander E, Wagle N, Van Allen EM. The Metastatic Prostate Cancer project (MPCproject): Translational genomics through direct patient engagement. Journal of Clinical Oncology. 36: 279-279. DOI: 10.1200/Jco.2018.36.6_Suppl.279 |
0.342 |
|
| 2018 |
Dunphy M, Jain E, Anastasio E, McGillicuddy M, Stoddard R, Thomas B, Balch S, Anderka K, Larkin K, Lennon N, Chen Y, Zimmer A, Baker EO, Maiwald S, Lapan JH, ... ... Lander E, et al. Abstract 5384: The Angiosarcoma Project: Generating the genomic landscape of an exceedingly rare cancer through a nationwide patient-driven initiative Cancer Research. 78: 5384-5384. DOI: 10.1158/1538-7445.Am2018-5384 |
0.391 |
|
| 2017 |
Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Lander ES, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179 |
0.795 |
|
| 2017 |
Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, ... ... Lander ES, et al. Cohesin Loss Eliminates All Loop Domains. Cell. 171: 305-320.e24. PMID 28985562 DOI: 10.1016/J.Cell.2017.09.026 |
0.512 |
|
| 2017 |
Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, et al. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nature Genetics. PMID 28825726 DOI: 10.1038/Ng.3934 |
0.537 |
|
| 2017 |
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, ... ... Lander ES, et al. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 170: 199-212.e20. PMID 28666119 DOI: 10.1016/J.Cell.2017.06.011 |
0.74 |
|
| 2017 |
Rheinbay E, Parasuraman P, Grimsby J, Tiao G, Engreitz JM, Kim J, Lawrence MS, Taylor-Weiner A, Rodriguez-Cuevas S, Rosenberg M, Hess J, Stewart C, Maruvka YE, Stojanov P, Cortes ML, ... ... Lander ES, et al. Recurrent and functional regulatory mutations in breast cancer. Nature. PMID 28658208 DOI: 10.1038/Nature22992 |
0.566 |
|
| 2017 |
Saleheen D, Natarajan P, Armean IM, Zhao W, Rasheed A, Khetarpal SA, Won HH, Karczewski KJ, O'Donnell-Luria AH, Samocha KE, Weisburd B, Gupta N, Zaidi M, Samuel M, Imran A, ... ... Lander ES, et al. Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity. Nature. 544: 235-239. PMID 28406212 DOI: 10.1038/Nature22034 |
0.474 |
|
| 2017 |
Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Abdulhay NJ, King DS, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 168: 1053-1064.e15. PMID 28283061 DOI: 10.1016/J.Cell.2017.02.026 |
0.512 |
|
| 2017 |
Grossman SR, Zhang X, Wang L, Engreitz J, Melnikov A, Rogov P, Tewhey R, Isakova A, Deplancke B, Bernstein BE, Mikkelsen TS, Lander ES. Systematic dissection of genomic features determining transcription factor binding and enhancer function. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137873 DOI: 10.1073/Pnas.1621150114 |
0.524 |
|
| 2016 |
Emdin CA, Khera AV, Natarajan P, Klarin D, Won HH, Peloso GM, Stitziel NO, Nomura A, Zekavat SM, Bick AG, Gupta N, Asselta R, Duga S, Merlini PA, Correa A, ... ... Lander E, et al. Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. Journal of the American College of Cardiology. 68: 2761-2772. PMID 28007139 DOI: 10.1016/J.Jacc.2016.10.033 |
0.342 |
|
| 2016 |
Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, ... ... Lander ES, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Reports. 17: 1206. PMID 27760322 DOI: 10.1016/J.Celrep.2016.10.009 |
0.51 |
|
| 2016 |
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Lander ES, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642 |
0.795 |
|
| 2016 |
Burger JA, Landau DA, Taylor-Weiner A, Bozic I, Zhang H, Sarosiek K, Wang L, Stewart C, Fan J, Hoellenriegel J, Sivina M, Dubuc AM, Fraser C, Han Y, Li S, ... ... Lander E, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nature Communications. 7: 11589. PMID 27199251 DOI: 10.1038/Ncomms11589 |
0.302 |
|
| 2016 |
Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, ... ... Lander ES, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Reports. PMID 27149842 DOI: 10.1016/J.Celrep.2016.03.075 |
0.556 |
|
| 2016 |
Khera AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X, van Leeuwen EM, Natarajan P, Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N, Nomura A, Kessler T, ... ... Lander E, et al. Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. Journal of the American College of Cardiology. PMID 27050191 DOI: 10.1016/J.Jacc.2016.03.520 |
0.302 |
|
| 2016 |
Giannakis M, Mu JX, Shukla S, Qian ZR, Cohen O, Nishihara R, Cao Y, Yamauchi M, Sukawa Y, Nosho K, Ng K, Meyerhardt JA, Lawrence M, Gabriel SB, Lander E, et al. Novel driver genes and genomic predictors of immune infiltrates in colorectal cancer. Journal of Clinical Oncology. 34: 557-557. DOI: 10.1200/Jco.2016.34.4_Suppl.557 |
0.392 |
|
| 2016 |
Wagle N, Painter C, Krevalin M, Oh C, Anderka K, Larkin K, Lennon N, Dillon D, Frank E, Winer EP, Lander E, Golub T. The Metastatic Breast Cancer Project: A national direct-to-patient initiative to accelerate genomics research. Journal of Clinical Oncology. 34: LBA1519-LBA1519. DOI: 10.1200/Jco.2016.34.18_Suppl.Lba1519 |
0.313 |
|
| 2016 |
Wagle N, Painter C, Ilzarbe M, Allen EV, Frank E, Oh C, Krevalin M, Lloyd M, Anderka K, Kryukov G, Boehm J, Winer E, Lander E, Golub T. Abstract OT2-05-03: The metastatic breast cancer project: A national direct-to-patient research initiative to accelerate genomics research Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-Ot2-05-03 |
0.332 |
|
| 2015 |
Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Lander ES, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369 |
0.498 |
|
| 2015 |
Kamburov A, Lawrence MS, Polak P, Leshchiner I, Lage K, Golub TR, Lander ES, Getz G. Comprehensive assessment of cancer missense mutation clustering in protein structures. Proceedings of the National Academy of Sciences of the United States of America. 112: E5486-95. PMID 26392535 DOI: 10.1073/pnas.1516373112 |
0.535 |
|
| 2015 |
Andersen KG, Shapiro BJ, Matranga CB, Sealfon R, Lin AE, Moses LM, Folarin OA, Goba A, Odia I, Ehiane PE, Momoh M, England EM, Winnicki S, Branco LM, Gire SK, ... ... Lander ES, et al. Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus. Cell. 162: 738-50. PMID 26276630 DOI: 10.1016/J.Cell.2015.07.020 |
0.687 |
|
| 2015 |
Stachler MD, Taylor-Weiner A, Peng S, McKenna A, Agoston AT, Odze RD, Davison JM, Nason KS, Loda M, Leshchiner I, Stewart C, Stojanov P, Seepo S, Lawrence MS, Ferrer-Torres D, ... ... Lander ES, et al. Paired exome analysis of Barrett's esophagus and adenocarcinoma. Nature Genetics. 47: 1047-55. PMID 26192918 DOI: 10.1038/Ng.3343 |
0.569 |
|
| 2015 |
Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Lander E, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121 |
0.744 |
|
| 2015 |
Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, ... ... Lander ES, et al. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 518: 102-6. PMID 25487149 DOI: 10.1038/Nature13917 |
0.488 |
|
| 2015 |
Giannakis M, Shukla S, Mu JX, Nishihara R, Yamauchi M, Sukawa Y, Qian ZR, Nosho K, Inamura K, Bahl S, Ng K, Chan AT, Meyerhardt JA, Gabriel SB, Lander E, et al. Comprehensive molecular characterization of colorectal cancer reveals genomic predictors of immune cell infiltrates. Journal of Clinical Oncology. 33: 3505-3505. DOI: 10.1200/Jco.2015.33.15_Suppl.3505 |
0.325 |
|
| 2015 |
Landau DA, Tausch E, Böttcher S, Stewart C, Bozic I, Leischner I, Rosebrock D, Taylor-Weiner A, Mertens D, Sougnez C, Kless S, Kneba M, Ritgen M, Kluth S, Bahlo J, ... ... Lander E, et al. Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy Blood. 126: 362-362. DOI: 10.1182/Blood.V126.23.362.362 |
0.328 |
|
| 2015 |
Auton A, Abecasis GR, Altshuler DM, Durbin RM, Bentley DR, Chakravarti A, Clark AG, Donnelly P, Eichler EE, Flicek P, Gabriel SB, Gibbs RA, Green ED, Hurles ME, Knoppers BM, ... ... Lander ES, et al. A global reference for human genetic variation Nature. 526: 68-74. DOI: 10.1038/nature15393 |
0.443 |
|
| 2015 |
Andersen KG, Shapiro BJ, Matranga CB, Sealfon R, Lin AE, Moses LM, Folarin OA, Goba A, Odia I, Ehiane PE, Momoh M, England EM, Winnicki S, Branco LM, Gire SK, ... ... Lander ES, et al. Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus Cell. 162: 738-750. DOI: 10.1016/j.cell.2015.07.020 |
0.662 |
|
| 2014 |
Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, ... ... Lander ES, et al. Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 111: E5564-73. PMID 25512523 DOI: 10.1073/Pnas.1419260111 |
0.583 |
|
| 2014 |
Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, ... ... Lander ES, et al. Inactivating mutations in NPC1L1 and protection from coronary heart disease. The New England Journal of Medicine. 371: 2072-82. PMID 25390462 DOI: 10.1056/Nejmoa1405386 |
0.419 |
|
| 2014 |
Giannakis M, Hodis E, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB, Lander ES, Getz G, et al. RNF43 is frequently mutated in colorectal and endometrial cancers. Nature Genetics. 46: 1264-6. PMID 25344691 DOI: 10.1038/Ng.3127 |
0.513 |
|
| 2014 |
Weisenfeld NI, Yin S, Sharpe T, Lau B, Hegarty R, Holmes L, Sogoloff B, Tabbaa D, Williams L, Russ C, Nusbaum C, Lander ES, MacCallum I, Jaffe DB. Comprehensive variation discovery in single human genomes. Nature Genetics. 46: 1350-5. PMID 25326702 DOI: 10.1038/Ng.3121 |
0.334 |
|
| 2014 |
Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki S, Matranga CB, ... ... Lander ES, et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science (New York, N.Y.). 345: 1369-72. PMID 25214632 DOI: 10.1126/Science.1259657 |
0.706 |
|
| 2014 |
Cho J, Bass AJ, Lawrence MS, Cibulskis K, Cho A, Lee SN, Yamauchi M, Wagle N, Pochanard P, Kim N, Park AK, Won J, Hur HS, Greulich H, Ogino S, ... ... Lander ES, et al. Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab. Molecular Cancer. 13: 141. PMID 24894453 DOI: 10.1186/1476-4598-13-141 |
0.503 |
|
| 2014 |
Van Allen EM, Wagle N, Stojanov P, Perrin DL, Cibulskis K, Marlow S, Jane-Valbuena J, Friedrich DC, Kryukov G, Carter SL, McKenna A, Sivachenko A, Rosenberg M, Kiezun A, Voet D, ... ... Lander ES, et al. Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nature Medicine. 20: 682-8. PMID 24836576 DOI: 10.1038/Nm.3559 |
0.499 |
|
| 2014 |
Wang L, Shalek AK, Lawrence M, Ding R, Gaublomme JT, Pochet N, Stojanov P, Sougnez C, Shukla SA, Stevenson KE, Zhang W, Wong J, Sievers QL, MacDonald BT, Vartanov AR, ... ... Lander E, et al. Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. Blood. 124: 1089-98. PMID 24778153 DOI: 10.1182/Blood-2014-01-552067 |
0.398 |
|
| 2014 |
Hoeppner MP, Lundquist A, Pirun M, Meadows JR, Zamani N, Johnson J, Sundström G, Cook A, FitzGerald MG, Swofford R, Mauceli E, Moghadam BT, Greka A, Alföldi J, Abouelleil A, ... ... Lander ES, et al. An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts. Plos One. 9: e91172. PMID 24625832 DOI: 10.1371/Journal.Pone.0091172 |
0.33 |
|
| 2014 |
Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, ... ... Lander E, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965 |
0.418 |
|
| 2014 |
Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, O'Dushlaine C, Chambert K, Bergen SE, Kähler A, Duncan L, Stahl E, Genovese G, Fernández E, Collins MO, ... ... Lander ES, et al. A polygenic burden of rare disruptive mutations in schizophrenia. Nature. 506: 185-90. PMID 24463508 DOI: 10.1038/Nature12975 |
0.303 |
|
| 2014 |
Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nature Structural & Molecular Biology. 21: 198-206. PMID 24463464 DOI: 10.1038/Nsmb.2764 |
0.612 |
|
| 2014 |
Zuk O, Schaffner SF, Samocha K, Do R, Hechter E, Kathiresan S, Daly MJ, Neale BM, Sunyaev SR, Lander ES. Searching for missing heritability: designing rare variant association studies. Proceedings of the National Academy of Sciences of the United States of America. 111: E455-64. PMID 24443550 DOI: 10.1073/Pnas.1322563111 |
0.475 |
|
| 2014 |
Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, Meyerson M, Gabriel SB, Lander ES, Getz G. Discovery and saturation analysis of cancer genes across 21 tumour types. Nature. 505: 495-501. PMID 24390350 DOI: 10.1038/Nature12912 |
0.588 |
|
| 2014 |
Landau DA, Stewart C, Reiter JG, Lawrence M, Sougnez C, Brown JR, Lopez-Guillermo A, Gabriel S, Lander E, Neuberg DS, López-Otín C, Campo E, Getz G, Wu CJ. Novel Putative Driver Gene Mutations in Chronic Lymphocytic Leukemia (CLL): Results from a Combined Analysis of Whole-Exome Sequencing of 262 Primary CLL Samples Blood. 124: 1952-1952. DOI: 10.1182/Blood.V124.21.1952.1952 |
0.418 |
|
| 2014 |
Kasar S, Tiao G, Improgo R, Kiezun A, Sougnez C, Bahl S, Fernandes SM, Vartanov AR, Hoang K, Gabriel S, Landau DA, Wu CJ, Lander E, Kim HT, Getz G, et al. Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements Blood. 124: 1939-1939. DOI: 10.1182/Blood.V124.21.1939.1939 |
0.416 |
|
| 2014 |
Landau DA, Tausch E, Taylor-Weiner AN, Bottcher S, Bahlo J, Stewart C, Edelmann J, Kluth S, Mertens D, Kneba M, Kless S, Sougnez C, Fischer K, Ritgen M, Gabriel S, ... Lander E, et al. Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial Blood. 124: 1938-1938. DOI: 10.1182/Blood.V124.21.1938.1938 |
0.38 |
|
| 2014 |
Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Sloan AE, Cohen ML, Meir EGV, Scarpace L, Laird PW, Weinstein JN, Lander E, et al. Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma Cancer Research. 74: 984-984. DOI: 10.1158/1538-7445.Am2014-984 |
0.365 |
|
| 2014 |
Kim H, Zheng S, Amini S, Virk S, Mikkelsen T, Brat D, Sougnez C, Muller F, Hu J, Sloan A, Cohen M, Van Meir E, Scarpace L, Lander E, Gabriel S, et al. GE-17 * ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: v100-v100. DOI: 10.1093/Neuonc/Nou256.17 |
0.345 |
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| 2014 |
Verhaak RGW, Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, ... ... Lander E, et al. THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: iii3-iii3. DOI: 10.1093/Neuonc/Nou206.10 |
0.359 |
|
| 2014 |
Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, Zheng S, Chakravarty D, Sanborn J, Berman S, Beroukhim R, Bernard B, Wu C, Genovese G, Shmulevich I, ... ... Lander E, et al. The Somatic Genomic Landscape of Glioblastoma Cell. 157: 753. DOI: 10.1016/J.Cell.2014.04.004 |
0.396 |
|
| 2013 |
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Lander E, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034 |
0.423 |
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| 2013 |
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, ... ... Lander ES, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 499: 214-8. PMID 23770567 DOI: 10.1038/Nature12213 |
0.767 |
|
| 2013 |
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, ... ... Lander ES, et al. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell. 153: 1149-63. PMID 23664763 DOI: 10.1016/J.Cell.2013.04.037 |
0.53 |
|
| 2013 |
Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, ... ... Lander ES, et al. Punctuated evolution of prostate cancer genomes. Cell. 153: 666-77. PMID 23622249 DOI: 10.1016/J.Cell.2013.03.021 |
0.745 |
|
| 2013 |
Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, ... ... Lander ES, et al. The African coelacanth genome provides insights into tetrapod evolution. Nature. 496: 311-6. PMID 23598338 DOI: 10.1038/Nature12027 |
0.313 |
|
| 2013 |
Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefler E, McKenna A, Carter SL, Cibulskis K, Sivachenko A, Saksena G, ... ... Lander ES, et al. Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nature Genetics. 45: 478-86. PMID 23525077 DOI: 10.1038/Ng.2591 |
0.598 |
|
| 2013 |
Landau DA, Carter SL, Stojanov P, McKenna A, Stevenson K, Lawrence MS, Sougnez C, Stewart C, Sivachenko A, Wang L, Wan Y, Zhang W, Shukla SA, Vartanov A, Fernandes SM, ... ... Lander ES, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell. 152: 714-26. PMID 23415222 DOI: 10.1016/J.Cell.2013.01.019 |
0.532 |
|
| 2013 |
Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, ... ... Lander ES, et al. Identifying recent adaptations in large-scale genomic data. Cell. 152: 703-13. PMID 23415221 DOI: 10.1016/J.Cell.2013.01.035 |
0.816 |
|
| 2013 |
Germain AR, Carmody LC, Nag PP, Morgan B, Verplank L, Fernandez C, Donckele E, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, Schreiber SL, Munoz B. Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorganic & Medicinal Chemistry Letters. 23: 1834-8. PMID 23403082 DOI: 10.1016/J.Bmcl.2013.01.025 |
0.335 |
|
| 2013 |
Kirby A, Gnirke A, Jaffe DB, Barešová V, Pochet N, Blumenstiel B, Ye C, Aird D, Stevens C, Robinson JT, Cabili MN, Gat-Viks I, Kelliher E, Daza R, DeFelice M, ... ... Lander ES, et al. Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing. Nature Genetics. 45: 299-303. PMID 23396133 DOI: 10.1038/Ng.2543 |
0.495 |
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| 2013 |
Cibulskis K, Lawrence MS, Carter SL, Sivachenko A, Jaffe D, Sougnez C, Gabriel S, Meyerson M, Lander ES, Getz G. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nature Biotechnology. 31: 213-9. PMID 23396013 DOI: 10.1038/Nbt.2514 |
0.583 |
|
| 2013 |
Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, ... ... Lander ES, et al. The genetic landscape of high-risk neuroblastoma. Nature Genetics. 45: 279-84. PMID 23334666 DOI: 10.1038/Ng.2529 |
0.575 |
|
| 2013 |
Drier Y, Lawrence MS, Carter SL, Stewart C, Gabriel SB, Lander ES, Meyerson M, Beroukhim R, Getz G. Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Genome Research. 23: 228-35. PMID 23124520 DOI: 10.1101/Gr.141382.112 |
0.605 |
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| 2013 |
McFadden DG, Papagiannakopoulos T, Cibulskis K, Stewart C, Carter S, Taylor-Weiner A, Bhutkar A, Sougnez C, Dooley A, Shefler E, Lander E, Gabriel S, Getz G, Jacks T. Abstract 1084: Comprehensive genomic analysis of murine small cell lung carcinoma uncovers recurrent Pten alterations that drive tumor progression and alter tumor genome evolution. Cancer Research. 73: 1084-1084. DOI: 10.1158/1538-7445.Am2013-1084 |
0.448 |
|
| 2012 |
Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, ... ... Lander ES, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 150: 1107-20. PMID 22980975 DOI: 10.1016/J.Cell.2012.08.029 |
0.751 |
|
| 2012 |
Hammerman PS, Voet D, Lawrence MS, Jing R, Cibulskis K, Sivachenko A, Stojanov P, McKenna A, Lander ES, Gabriel S, Getz G, Imielinski M, Helman E, Hernandez B, Pho NH, et al. Comprehensive genomic characterization of squamous cell lung cancers Nature. 489: 519-525. PMID 22960745 DOI: 10.1038/Nature11404 |
0.692 |
|
| 2012 |
Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, ... ... Lander ES, et al. A landscape of driver mutations in melanoma. Cell. 150: 251-63. PMID 22817889 DOI: 10.1016/J.Cell.2012.06.024 |
0.742 |
|
| 2012 |
Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, ... ... Lander ES, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/Nature11252 |
0.343 |
|
| 2012 |
Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, ... ... Lander ES, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 486: 405-9. PMID 22722202 DOI: 10.1038/Nature11154 |
0.553 |
|
| 2012 |
Berger MF, Hodis E, Heffernan TP, Deribe YL, Lawrence MS, Protopopov A, Ivanova E, Watson IR, Nickerson E, Ghosh P, Zhang H, Zeid R, Ren X, Cibulskis K, Sivachenko AY, ... ... Lander ES, et al. Melanoma genome sequencing reveals frequent PREX2 mutations. Nature. 485: 502-6. PMID 22622578 DOI: 10.1038/Nature11071 |
0.776 |
|
| 2012 |
Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, ... ... Lander ES, et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nature Genetics. 44: 685-9. PMID 22610119 DOI: 10.1038/Ng.2279 |
0.74 |
|
| 2012 |
Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, et al. Absolute quantification of somatic DNA alterations in human cancer. Nature Biotechnology. 30: 413-21. PMID 22544022 DOI: 10.1038/Nbt.2203 |
0.696 |
|
| 2012 |
Germain AR, Carmody LC, Morgan B, Fernandez C, Forbeck E, Lewis TA, Nag PP, Ting A, VerPlank L, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, et al. Identification of a selective small molecule inhibitor of breast cancer stem cells. Bioorganic & Medicinal Chemistry Letters. 22: 3571-4. PMID 22503247 DOI: 10.1016/J.Bmcl.2012.01.035 |
0.325 |
|
| 2012 |
Melnikov A, Murugan A, Zhang X, Tesileanu T, Wang L, Rogov P, Feizi S, Gnirke A, Callan CG, Kinney JB, Kellis M, Lander ES, Mikkelsen TS. Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nature Biotechnology. 30: 271-7. PMID 22371084 DOI: 10.1038/Nbt.2137 |
0.794 |
|
| 2012 |
Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, Cruz-Gordillo P, Knoechel B, Asmann YW, Slager SL, Novak AJ, Dogan A, Ansell SM, Link BK, Zou L, ... ... Lander ES, et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proceedings of the National Academy of Sciences of the United States of America. 109: 3879-84. PMID 22343534 DOI: 10.1073/Pnas.1121343109 |
0.56 |
|
| 2012 |
Cabili M, Lander E, Sabeti P, Regev A, Rinn JL, Rinn JL, Rinn JL, Trapnell C, Trapnell C, Goff L, Goff L, Broadbent K, Broadbent K, Guttman M. Abstract IA4: Linking RNA to human health and disease Cancer Research. 72: IA4-IA4. DOI: 10.1158/1538-7445.Nonrna12-Ia4 |
0.639 |
|
| 2012 |
Imielinski M, Hernandez B, Lawrence M, Hodis E, Kryukov G, Stojanov P, Sivachenko A, Cibulskis K, Sougnez C, Auclair D, Ardlie K, Banerji S, Hammerman P, Thomas RK, Gabriel S, ... Lander E, et al. Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma Cancer Research. 72: 1682-1682. DOI: 10.1158/1538-7445.Am2012-1682 |
0.438 |
|
| 2011 |
Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K, Werner L, Sivachenko A, DeLuca DS, Zhang L, Zhang W, Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, ... ... Lander ES, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. The New England Journal of Medicine. 365: 2497-506. PMID 22150006 DOI: 10.1056/Nejmoa1109016 |
0.561 |
|
| 2011 |
Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G, Mauceli E, Ward LD, Lowe CB, Holloway AK, Clamp M, Gnerre S, ... ... Lander ES, et al. A high-resolution map of human evolutionary constraint using 29 mammals. Nature. 478: 476-82. PMID 21993624 DOI: 10.1038/Nature10530 |
0.792 |
|
| 2011 |
Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, Sougnez C, Voet D, Saksena G, Sivachenko A, Jing R, Parkin M, Pugh T, Verhaak RG, Stransky N, ... ... Lander ES, et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics. 43: 964-8. PMID 21892161 DOI: 10.1038/Ng.936 |
0.586 |
|
| 2011 |
Alföldi J, Di Palma F, Grabherr M, Williams C, Kong L, Mauceli E, Russell P, Lowe CB, Glor RE, Jaffe JD, Ray DA, Boissinot S, Shedlock AM, Botka C, Castoe TA, ... ... Lander ES, et al. The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature. 477: 587-91. PMID 21881562 DOI: 10.1038/Nature10390 |
0.313 |
|
| 2011 |
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, ... ... Lander ES, et al. The mutational landscape of head and neck squamous cell carcinoma. Science (New York, N.Y.). 333: 1157-60. PMID 21798893 DOI: 10.1126/Science.1208130 |
0.747 |
|
| 2011 |
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, ... ... Lander ES, et al. Initial genome sequencing and analysis of multiple myeloma. Nature. 471: 467-72. PMID 21430775 DOI: 10.1038/Nature09837 |
0.81 |
|
| 2011 |
Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, ... ... Lander ES, et al. The genomic complexity of primary human prostate cancer. Nature. 470: 214-20. PMID 21307934 DOI: 10.1038/Nature09744 |
0.734 |
|
| 2011 |
Lander ES. Initial impact of the sequencing of the human genome. Nature. 470: 187-97. PMID 21307931 DOI: 10.1038/nature09792 |
0.307 |
|
| 2011 |
Robinson JT, Thorvaldsdóttir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP. Integrative genomics viewer. Nature Biotechnology. 29: 24-6. PMID 21221095 DOI: 10.1038/Nbt.1754 |
0.696 |
|
| 2011 |
Proia TA, Keller P, Gupta P, Klebba I, Jones A, Sedic M, Gilmore H, Tung N, Naber S, Schnitt S, Lander E, Kuperwasser C. Abstract 916: BRCA1 mutations impair breast epithelial differentiation through upregulation of the transcriptional repressor Slug Cancer Research. 71: 916-916. DOI: 10.1158/1538-7445.Am2011-916 |
0.327 |
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| 2010 |
Bernstein BE, Stamatoyannopoulos JA, Costello JF, Ren B, Milosavljevic A, Meissner A, Kellis M, Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M, Lander ES, Mikkelsen TS, Thomson JA. The NIH Roadmap Epigenomics Mapping Consortium. Nature Biotechnology. 28: 1045-8. PMID 20944595 DOI: 10.1038/Nbt1010-1045 |
0.61 |
|
| 2010 |
Mikkelsen TS, Xu Z, Zhang X, Wang L, Gimble JM, Lander ES, Rosen ED. Comparative epigenomic analysis of murine and human adipogenesis. Cell. 143: 156-69. PMID 20887899 DOI: 10.1016/J.Cell.2010.09.006 |
0.302 |
|
| 2010 |
Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, ... ... Lander ES, et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nature Genetics. 42: 715-21. PMID 20601955 DOI: 10.1038/Ng.619 |
0.708 |
|
| 2010 |
Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell. 6: 591-602. PMID 20569696 DOI: 10.1016/J.Stem.2010.03.016 |
0.492 |
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| 2010 |
Green RE, Krause J, Briggs AW, Maricic T, Stenzel U, Kircher M, Patterson N, Li H, Zhai W, Fritz MH, Hansen NF, Durand EY, Malaspinas AS, Jensen JD, Marques-Bonet T, ... ... Lander ES, et al. A draft sequence of the Neandertal genome. Science (New York, N.Y.). 328: 710-22. PMID 20448178 DOI: 10.1126/Science.1188021 |
0.316 |
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| 2010 |
Berger MF, Levin JZ, Vijayendran K, Sivachenko A, Adiconis X, Maguire J, Johnson LA, Robinson J, Verhaak RG, Sougnez C, Onofrio RC, Ziaugra L, Cibulskis K, Laine E, Barretina J, ... ... Lander ES, et al. Integrative analysis of the melanoma transcriptome. Genome Research. 20: 413-27. PMID 20179022 DOI: 10.1101/Gr.103697.109 |
0.725 |
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| 2010 |
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... ... Lander ES, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822 |
0.794 |
|
| 2010 |
Burrage LC, Baskin-Hill AE, Sinasac DS, Singer JB, Croniger CM, Kirby A, Kulbokas EJ, Daly MJ, Lander ES, Broman KW, Nadeau JH. Genetic resistance to diet-induced obesity in chromosome substitution strains of mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 115-29. PMID 20127486 DOI: 10.1007/S00335-010-9247-9 |
0.351 |
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| 2010 |
Stratton MR, Lander E. Leena Peltonen 1952–2010 Cell. 141: 208-209. DOI: 10.1016/J.Cell.2010.04.001 |
0.405 |
|
| 2009 |
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, ... ... Lander ES, et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science (New York, N.Y.). 326: 289-93. PMID 19815776 DOI: 10.1126/Science.1181369 |
0.576 |
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| 2009 |
Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, Regev A, Lander ES, Rinn JL. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proceedings of the National Academy of Sciences of the United States of America. 106: 11667-72. PMID 19571010 DOI: 10.1073/Pnas.0904715106 |
0.564 |
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| 2009 |
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, ... ... Lander ES, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458: 223-7. PMID 19182780 DOI: 10.1038/Nature07672 |
0.661 |
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| 2009 |
Chiang DY, Getz G, Jaffe DB, O'Kelly MJ, Zhao X, Carter SL, Russ C, Nusbaum C, Meyerson M, Lander ES. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nature Methods. 6: 99-103. PMID 19043412 DOI: 10.1038/Nmeth.1276 |
0.323 |
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| 2009 |
Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newberg LA. Corrigendum to "MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations" [Genomics 1 (1987) 174-181] (PII:0888-7543(87)90010-3) Genomics. 93: 398. DOI: 10.1016/J.Ygeno.2008.12.003 |
0.425 |
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| 2008 |
Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19910-4. PMID 19066216 DOI: 10.1073/Pnas.0810388105 |
0.437 |
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| 2008 |
Altshuler D, Daly MJ, Lander ES. Genetic mapping in human disease. Science (New York, N.Y.). 322: 881-8. PMID 18988837 DOI: 10.1126/Science.1156409 |
0.603 |
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| 2008 |
Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. Plos Genetics. 4: e1000242. PMID 18974828 DOI: 10.1371/Journal.Pgen.1000242 |
0.521 |
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| 2008 |
Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, ... ... Lander ES, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 455: 1069-75. PMID 18948947 DOI: 10.1038/Nature07423 |
0.755 |
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| 2008 |
McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WKA, Bogler O, Weinstein JN, VandenBerg S, Berger M, ... ... Lander ES, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. 455: 1061-1068. PMID 18772890 DOI: 10.1038/Nature07385 |
0.312 |
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| 2008 |
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/Nature07107 |
0.543 |
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| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/Nature07056 |
0.524 |
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| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis (Nature (2008) 454, (49-55)) Nature. 454: 794. DOI: 10.1038/Nature07196 |
0.488 |
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| 2007 |
Clamp M, Fry B, Kamal M, Xie X, Cuff J, Lin MF, Kellis M, Lindblad-Toh K, Lander ES. Distinguishing protein-coding and noncoding genes in the human genome. Proceedings of the National Academy of Sciences of the United States of America. 104: 19428-33. PMID 18040051 DOI: 10.1073/Pnas.0709013104 |
0.527 |
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| 2007 |
Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, ... ... Lander E, et al. Evolution of genes and genomes on the Drosophila phylogeny. Nature. 450: 203-18. PMID 17994087 DOI: 10.1038/Nature06341 |
0.818 |
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| 2007 |
Miller W, Rosenbloom K, Hardison RC, Hou M, Taylor J, Raney B, Burhans R, King DC, Baertsch R, Blankenberg D, Kosakovsky Pond SL, Nekrutenko A, Giardine B, Harris RS, Tyekucheva S, ... ... Lander ES, et al. 28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Research. 17: 1797-808. PMID 17984227 DOI: 10.1101/Gr.6761107 |
0.322 |
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| 2007 |
Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... ... Lander ES, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358 |
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| 2007 |
Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES, Frazer KA, Ballinger DG, et al. Genome-wide detection and characterization of positive selection in human populations. Nature. 449: 913-8. PMID 17943131 DOI: 10.1038/Nature06250 |
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| 2007 |
Manolio TA, Rodriguez LL, Brooks L, Abecasis G, Ballinger D, Daly M, Donnelly P, Faraone SV, Frazer K, Gabriel S, Gejman P, ... ... Lander E, et al. New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nature Genetics. 39: 1045-51. PMID 17728769 DOI: 10.1038/Ng2127 |
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| 2007 |
Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, et al. Risk alleles for multiple sclerosis identified by a genomewide study. The New England Journal of Medicine. 357: 851-62. PMID 17660530 DOI: 10.1056/Nejmoa073493 |
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| 2007 |
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Lander ES, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/Nature06008 |
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| 2007 |
Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, ... ... Lander ES, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 447: 799-816. PMID 17571346 DOI: 10.1038/Nature05874 |
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| 2007 |
Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber M, Gentles AJ, Goodstadt L, Heger A, Jurka J, Kamal M, Mauceli E, Searle SM, Sharpe T, ... ... Lander ES, et al. Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature. 447: 167-77. PMID 17495919 DOI: 10.1038/Nature05805 |
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| 2007 |
Xie X, Mikkelsen TS, Gnirke A, Lindblad-Toh K, Kellis M, Lander ES. Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proceedings of the National Academy of Sciences of the United States of America. 104: 7145-50. PMID 17442748 DOI: 10.1073/Pnas.0701811104 |
0.557 |
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| 2007 |
Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 128: 669-81. PMID 17320505 DOI: 10.1016/J.Cell.2007.01.033 |
0.572 |
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| 2007 |
Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, ... ... Lander ES, et al. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Annals of Neurology. 61: 228-36. PMID 17252545 DOI: 10.1002/Ana.21063 |
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| 2006 |
Sabeti PC, Schaffner SF, Fry B, Lohmueller J, Varilly P, Shamovsky O, Palma A, Mikkelsen TS, Altshuler D, Lander ES. Positive natural selection in the human lineage. Science (New York, N.Y.). 312: 1614-20. PMID 16778047 DOI: 10.1126/Science.1124309 |
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| 2006 |
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041 |
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| 2006 |
Tello-Ruiz MK, Curley C, DelMonte T, Giallourakis C, Kirby A, Miller K, Wild G, Cohen A, Langelier D, Latiano A, Wedemeyer N, Lander E, Schreiber S, Annese V, Daly MJ, et al. Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19. European Journal of Human Genetics : Ejhg. 14: 780-90. PMID 16570073 DOI: 10.1038/Sj.Ejhg.5201612 |
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| 2006 |
Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, ... ... Lander ES, et al. Human chromosome 11 DNA sequence and analysis including novel gene identification. Nature. 440: 497-500. PMID 16554811 DOI: 10.1038/Nature04632 |
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| 2006 |
Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, Taudien S, Garber M, Kodira CD, Schueler MG, Shimizu A, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, ... ... Lander ES, et al. DNA sequence and analysis of human chromosome 8. Nature. 439: 331-5. PMID 16421571 DOI: 10.1038/nature04406 |
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| 2006 |
Walsh EC, Sabeti P, Hutcheson HB, Fry B, Schaffner SF, de Bakker PI, Varilly P, Palma AA, Roy J, Cooper R, Winkler C, Zeng Y, de The G, Lander ES, O'Brien S, et al. Searching for signals of evolutionary selection in 168 genes related to immune function. Human Genetics. 119: 92-102. PMID 16362345 DOI: 10.1007/S00439-005-0090-0 |
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| 2005 |
Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, ... ... Lander ES, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 438: 803-19. PMID 16341006 DOI: 10.1038/Nature04338 |
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| 2005 |
Sabeti PC, Walsh E, Schaffner SF, Varilly P, Fry B, Hutcheson HB, Cullen M, Mikkelsen TS, Roy J, Patterson N, Cooper R, Reich D, Altshuler D, O'Brien S, Lander ES. The case for selection at CCR5-Delta32. Plos Biology. 3: e378. PMID 16248677 DOI: 10.1371/Journal.Pbio.0030378 |
0.49 |
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| 2005 |
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 102: 15545-50. PMID 16199517 DOI: 10.1073/Pnas.0506580102 |
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| 2005 |
Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, et al. A high-density screen for linkage in multiple sclerosis. American Journal of Human Genetics. 77: 454-67. PMID 16080120 DOI: 10.1086/444547 |
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| 2005 |
Margulies EH, Vinson JP, Miller W, Jaffe DB, Lindblad-Toh K, Chang JL, Green ED, Lander ES, Mullikin JC, Clamp M. An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing. Proceedings of the National Academy of Sciences of the United States of America. 102: 4795-800. PMID 15778292 DOI: 10.1073/Pnas.0409882102 |
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| 2005 |
Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature. 434: 338-45. PMID 15735639 DOI: 10.1038/Nature03441 |
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| 2005 |
Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ, McMahon S, Karlsson EK, Kulbokas EJ, Gingeras TR, Schreiber SL, Lander ES. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell. 120: 169-81. PMID 15680324 DOI: 10.1016/J.Cell.2005.01.001 |
0.618 |
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| 2005 |
Ackerman KG, Huang H, Grasemann H, Puma C, Singer JB, Hill AE, Lander E, Nadeau JH, Churchill GA, Drazen JM, Beier DR. Interacting genetic loci cause airway hyperresponsiveness. Physiological Genomics. 21: 105-11. PMID 15657107 DOI: 10.1152/Physiolgenomics.00267.2004 |
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| 2004 |
Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, ... ... Lander ES, et al. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature. 431: 946-57. PMID 15496914 DOI: 10.1038/Nature03025 |
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| 2004 |
Rioux JD, Karinen H, Kocher K, McMahon SG, Kärkkäinen P, Janatuinen E, Heikkinen M, Julkunen R, Pihlajamäki J, Naukkarinen A, Kosma VM, Daly MJ, Lander ES, Laakso M. Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci. American Journal of Medical Genetics. Part A. 130: 345-50. PMID 15386476 DOI: 10.1002/Ajmg.A.30072 |
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| 2004 |
Harbison CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne JB, Reynolds DB, Yoo J, Jennings EG, Zeitlinger J, Pokholok DK, Kellis M, Rolfe PA, ... ... Lander ES, et al. Transcriptional regulatory code of a eukaryotic genome. Nature. 431: 99-104. PMID 15343339 DOI: 10.1038/Nature02800 |
0.527 |
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| 2004 |
Michalkiewicz M, Michalkiewicz T, Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat. Physiological Genomics. 19: 228-32. PMID 15328390 DOI: 10.1152/Physiolgenomics.00126.2004 |
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| 2004 |
Kellis M, Patterson N, Birren B, Berger B, Lander ES. Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 11: 319-55. PMID 15285895 DOI: 10.1089/1066527041410319 |
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| 2004 |
Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Ivinson AJ, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, et al. Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. Human Molecular Genetics. 13: 1943-9. PMID 15238506 DOI: 10.1093/Hmg/Ddh202 |
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| 2004 |
Tantisira KG, Lake S, Silverman ES, Palmer LJ, Lazarus R, Silverman EK, Liggett SB, Gelfand EW, Rosenwasser LJ, Richter B, Israel E, Wechsler M, Gabriel S, Altshuler D, Lander E, et al. Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Human Molecular Genetics. 13: 1353-9. PMID 15128701 DOI: 10.1093/Hmg/Ddh149 |
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| 2004 |
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proceedings of the National Academy of Sciences of the United States of America. 101: 6570-5. PMID 15100410 DOI: 10.1073/Pnas.0401401101 |
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| 2004 |
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, et al. Assessing the impact of population stratification on genetic association studies. Nature Genetics. 36: 388-93. PMID 15052270 DOI: 10.1038/Ng1333 |
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| 2004 |
Kellis M, Birren BW, Lander ES. Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae. Nature. 428: 617-24. PMID 15004568 DOI: 10.1038/Nature02424 |
0.58 |
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| 2004 |
Sklar P, Pato MT, Kirby A, Petryshen TL, Medeiros H, Carvalho C, Macedo A, Dourado A, Coelho I, Valente J, Soares MJ, Ferreira CP, Lei M, Verner A, Hudson TJ, ... ... Lander E, et al. Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis. Molecular Psychiatry. 9: 213-8. PMID 14699422 DOI: 10.1038/Sj.Mp.4001418 |
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| 2003 |
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 115: 629-40. PMID 14651853 DOI: 10.1016/S0092-8674(03)00926-7 |
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| 2003 |
Moralejo DH, Park HA, Speros SJ, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat. Journal of Autoimmunity. 21: 315-24. PMID 14624755 DOI: 10.1016/S0896-8411(03)00138-0 |
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| 2003 |
Moses AM, Chiang DY, Kellis M, Lander ES, Eisen MB. Position specific variation in the rate of evolution in transcription factor binding sites. Bmc Evolutionary Biology. 3: 19. PMID 12946282 DOI: 10.1186/1471-2148-3-19 |
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| 2003 |
Walsh EC, Mather KA, Schaffner SF, Farwell L, Daly MJ, Patterson N, Cullen M, Carrington M, Bugawan TL, Erlich H, Campbell J, Barrett J, Miller K, Thomson G, Lander ES, et al. An integrated haplotype map of the human major histocompatibility complex. American Journal of Human Genetics. 73: 580-90. PMID 12920676 DOI: 10.1086/378101 |
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| 2003 |
Chiang DY, Moses AM, Kellis M, Lander ES, Eisen MB. Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts. Genome Biology. 4: R43. PMID 12844359 DOI: 10.1186/Gb-2003-4-7-R43 |
0.527 |
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| 2003 |
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, ... ... Lander ES, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics. 34: 267-73. PMID 12808457 DOI: 10.1038/Ng1180 |
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| 2003 |
Giallourakis C, Stoll M, Miller K, Hampe J, Lander ES, Daly MJ, Schreiber S, Rioux JD. IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis. American Journal of Human Genetics. 73: 205-11. PMID 12776251 DOI: 10.1086/376417 |
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| 2003 |
Kellis M, Patterson N, Endrizzi M, Birren B, Lander ES. Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature. 423: 241-54. PMID 12748633 DOI: 10.1038/Nature01644 |
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| 2003 |
Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, ... ... Lander ES, et al. The genome sequence of the filamentous fungus Neurospora crassa. Nature. 422: 859-68. PMID 12712197 DOI: 10.1038/Nature01554 |
0.36 |
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| 2003 |
Mootha VK, Lepage P, Miller K, Bunkenborg J, Reich M, Hjerrild M, Delmonte T, Villeneuve A, Sladek R, Xu F, Mitchell GA, Morin C, Mann M, Hudson TJ, Robinson B, ... ... Lander ES, et al. Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics. Proceedings of the National Academy of Sciences of the United States of America. 100: 605-10. PMID 12529507 DOI: 10.1073/Pnas.242716699 |
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| 2002 |
Wade CM, Kulbokas EJ, Kirby AW, Zody MC, Mullikin JC, Lander ES, Lindblad-Toh K, Daly MJ. The mosaic structure of variation in the laboratory mouse genome. Nature. 420: 574-8. PMID 12466852 DOI: 10.1038/Nature01252 |
0.429 |
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| 2002 |
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, ... ... Lander ES, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 420: 563-73. PMID 12466851 DOI: 10.1038/Nature01266 |
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| 2002 |
Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Lander ES, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262 |
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| 2002 |
Williams CN, Kocher K, Lander ES, Daly MJ, Rioux JD. Using a genome-wide scan and meta-analysis to identify a novel IBD locus and confirm previously identified IBD loci. Inflammatory Bowel Diseases. 8: 375-81. PMID 12454612 DOI: 10.1097/00054725-200211000-00001 |
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| 2002 |
Cowles CR, Hirschhorn JN, Altshuler D, Lander ES. Detection of regulatory variation in mouse genes. Nature Genetics. 32: 432-7. PMID 12410233 DOI: 10.1038/Ng992 |
0.536 |
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| 2002 |
Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, Gabriel SB, Platko JV, Patterson NJ, McDonald GJ, Ackerman HC, Campbell SJ, Altshuler D, Cooper R, Kwiatkowski D, ... ... Lander ES, et al. Detecting recent positive selection in the human genome from haplotype structure. Nature. 419: 832-7. PMID 12397357 DOI: 10.1038/Nature01140 |
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| 2002 |
Reich DE, Schaffner SF, Daly MJ, McVean G, Mullikin JC, Higgins JM, Richter DJ, Lander ES, Altshuler D. Human genome sequence variation and the influence of gene history, mutation and recombination. Nature Genetics. 32: 135-42. PMID 12161752 DOI: 10.1038/Ng947 |
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| 2002 |
MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, ... ... Lander ES, et al. Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Research. 12: 1029-39. PMID 12097339 DOI: 10.1101/Gr.412702 |
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| 2002 |
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, ... Lander ES, et al. The structure of haplotype blocks in the human genome. Science (New York, N.Y.). 296: 2225-9. PMID 12029063 DOI: 10.1126/Science.1069424 |
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| 2002 |
Galagan JE, Nusbaum C, Roy A, Endrizzi MG, Macdonald P, FitzHugh W, Calvo S, Engels R, Smirnov S, Atnoor D, Brown A, Allen N, Naylor J, Stange-Thomann N, DeArellano K, ... ... Lander E, et al. The genome of M. acetivorans reveals extensive metabolic and physiological diversity. Genome Research. 12: 532-42. PMID 11932238 DOI: 10.1101/Gr.223902 |
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| 2002 |
Waterston RH, Lander ES, Sulston JE. On the sequencing of the human genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3712-6. PMID 11880605 DOI: 10.1073/Pnas.042692499 |
0.305 |
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| 2002 |
Lindgren CM, Mahtani MM, Widén E, McCarthy MI, Daly MJ, Kirby A, Reeve MP, Kruglyak L, Parker A, Meyer J, Almgren P, Lehto M, Kanninen T, Tuomi T, Groop LC, ... Lander ES, et al. Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study. American Journal of Human Genetics. 70: 509-16. PMID 11791216 DOI: 10.1086/338629 |
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| 2002 |
Batzoglou S, Jaffe DB, Stanley K, Butler J, Gnerre S, Mauceli E, Berger B, Mesirov JP, Lander ES. ARACHNE: a whole-genome shotgun assembler. Genome Research. 12: 177-89. PMID 11779843 DOI: 10.1101/gr.208902 |
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| 2001 |
Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES. High-resolution haplotype structure in the human genome. Nature Genetics. 29: 229-32. PMID 11586305 DOI: 10.1038/Ng1001-229 |
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| 2001 |
Rioux JD, Daly MJ, Silverberg MS, Lindblad K, Steinhart H, Cohen Z, Delmonte T, Kocher K, Miller K, Guschwan S, Kulbokas EJ, O'Leary S, Winchester E, Dewar K, Green T, ... ... Lander ES, et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nature Genetics. 29: 223-8. PMID 11586304 DOI: 10.1038/Ng1001-223 |
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| 2001 |
Hudson TJ, Church DM, Greenaway S, Nguyen H, Cook A, Steen RG, Van Etten WJ, Castle AB, Strivens MA, Trickett P, Heuston C, Davison C, Southwell A, Hardisty R, Varela-Carver A, ... ... Lander ES, et al. A radiation hybrid map of mouse genes. Nature Genetics. 29: 201-5. PMID 11586302 DOI: 10.1038/Ng1001-201 |
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| 2001 |
Barclay J, Balaguero N, Mione M, Ackerman SL, Letts VA, Brodbeck J, Canti C, Meir A, Page KM, Kusumi K, Perez-Reyes E, Lander ES, Frankel WN, Gardiner RM, Dolphin AC, et al. Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6095-104. PMID 11487633 DOI: 10.1523/Jneurosci.21-16-06095.2001 |
0.586 |
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| 2001 |
Ardlie K, Liu-Cordero SN, Eberle MA, Daly M, Barrett J, Winchester E, Lander ES, Kruglyak L. Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion. American Journal of Human Genetics. 69: 582-9. PMID 11473344 DOI: 10.1086/323251 |
0.671 |
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| 2001 |
Hirschhorn JN, Lindgren CM, Daly MJ, Kirby A, Schaffner SF, Burtt NP, Altshuler D, Parker A, Rioux JD, Platko J, Gaudet D, Hudson TJ, Groop LC, Lander ES. Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height. American Journal of Human Genetics. 69: 106-16. PMID 11410839 DOI: 10.1086/321287 |
0.565 |
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| 2001 |
Sklar P, Schwab SG, Williams NM, Daly M, Schaffner S, Maier W, Albus M, Trixler M, Eichhammer P, Lerer B, Hallmayer J, Norton N, Williams H, Zammit S, Cardno AG, ... ... Lander ES, et al. Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls. Nature Genetics. 28: 126-8. PMID 11381257 DOI: 10.1038/88836 |
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| 2001 |
Inoue K, Dewar K, Katsanis N, Reiter LT, Lander ES, Devon KL, Wyman DW, Lupski JR, Birren B. The 1.4-Mb CMT1A duplication/HNPP deletion genomic region reveals unique genome architectural features and provides insights into the recent evolution of new genes. Genome Research. 11: 1018-33. PMID 11381029 DOI: 10.1101/Gr.180401 |
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| 2001 |
Reich DE, Cargill M, Bolk S, Ireland J, Sabeti PC, Richter DJ, Lavery T, Kouyoumjian R, Farhadian SF, Ward R, Lander ES. Linkage disequilibrium in the human genome. Nature. 411: 199-204. PMID 11346797 DOI: 10.1038/35075590 |
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| 2001 |
Laitinen T, Daly MJ, Rioux JD, Kauppi P, Laprise C, Petäys T, Green T, Cargill M, Haahtela T, Lander ES, Laitinen LA, Hudson TJ, Kere J. A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. Nature Genetics. 28: 87-91. PMID 11326283 DOI: 10.1038/Ng0501-87 |
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|
| 2001 |
Bartoloni L, Blouin JL, Maiti AK, Sainsbury A, Rossier C, Gehrig C, She JX, Marron MP, Lander ES, Meeks M, Chung E, Armengot M, Jorissen M, Scott HS, Delozier-Blanchet CD, et al. Axonemal beta heavy chain dynein DNAH9: cDNA sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia. Genomics. 72: 21-33. PMID 11247663 DOI: 10.1006/geno.2000.6462 |
0.314 |
|
| 2001 |
Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, ... ... Lander ES, et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature. 409: 928-33. PMID 11237013 DOI: 10.1038/35057149 |
0.626 |
|
| 2001 |
Lee N, Daly MJ, Delmonte T, Lander ES, Xu F, Hudson TJ, Mitchell GA, Morin CC, Robinson BH, Rioux JD. A genomewide linkage-disequilibrium scan localizes the Saguenay-Lac-Saint-Jean cytochrome oxidase deficiency to 2p16. American Journal of Human Genetics. 68: 397-409. PMID 11156535 DOI: 10.1086/318197 |
0.475 |
|
| 2001 |
Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E, Jaenisch R. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nature Genetics. 27: 31-9. PMID 11137995 DOI: 10.1038/83730 |
0.376 |
|
| 2001 |
Tanenbaum D, Lindblad-Toh K, Lander E, Meyerson M. High-throughput genomic analysis of small-cell lung cancer: allelotyping using Affymetrix HuSNP arrays Nature Genetics. 27: 90-90. DOI: 10.1038/87326 |
0.342 |
|
| 2000 |
Pajukanta P, Cargill M, Viitanen L, Nuotio I, Kareinen A, Perola M, Terwilliger JD, Kempas E, Daly M, Lilja H, Rioux JD, Brettin T, Viikari JS, Rönnemaa T, Laakso M, ... Lander ES, et al. Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. American Journal of Human Genetics. 67: 1481-93. PMID 11078477 DOI: 10.1086/316902 |
0.379 |
|
| 2000 |
Altshuler D, Pollara VJ, Cowles CR, Van Etten WJ, Baldwin J, Linton L, Lander ES. An SNP map of the human genome generated by reduced representation shotgun sequencing. Nature. 407: 513-6. PMID 11029002 DOI: 10.1038/35035083 |
0.515 |
|
| 2000 |
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, ... Lander ES, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genetics. 26: 76-80. PMID 10973253 DOI: 10.1038/79216 |
0.545 |
|
| 2000 |
Lindblad-Toh K, Tanenbaum DM, Daly MJ, Winchester E, Lui WO, Villapakkam A, Stanton SE, Larsson C, Hudson TJ, Johnson BE, Lander ES, Meyerson M. Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nature Biotechnology. 18: 1001-5. PMID 10973224 DOI: 10.1038/79269 |
0.461 |
|
| 2000 |
Batzoglou S, Pachter L, Mesirov JP, Berger B, Lander ES. Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Research. 10: 950-8. PMID 10899144 DOI: 10.1101/Gr.10.7.950 |
0.557 |
|
| 2000 |
Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, McLeod RS, Griffiths AM, Green T, Brettin TS, Stone V, Bull SB, Bitton A, Williams CN, Greenberg GR, Cohen Z, Lander ES, et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. American Journal of Human Genetics. 66: 1863-70. PMID 10777714 DOI: 10.1086/302913 |
0.409 |
|
| 2000 |
Bulman MP, Kusumi K, Frayling TM, McKeown C, Garrett C, Lander ES, Krumlauf R, Hattersley AT, Ellard S, Turnpenny PD. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nature Genetics. 24: 438-41. PMID 10742114 DOI: 10.1038/74307 |
0.686 |
|
| 2000 |
Lindblad-Toh K, Winchester E, Daly MJ, Wang DG, Hirschhorn JN, Laviolette JP, Ardlie K, Reich DE, Robinson E, Sklar P, Shah N, Thomas D, Fan JB, Gingeras T, Warrington J, ... ... Lander ES, et al. Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nature Genetics. 24: 381-6. PMID 10742102 DOI: 10.1038/74215 |
0.442 |
|
| 2000 |
Rioux J, Silverberg M, Daly M, Steinhart A, McLeod R, Griffiths A, Bull S, Greenberg G, Cohen Z, Lander E, Hudson T, Siminovitch K. Identification of two novel susceptibility loci in a Canadian inflammatory bowel disease population Digestive and Liver Disease. 32: A20. DOI: 10.1016/S1590-8658(00)80125-5 |
0.34 |
|
| 2000 |
Szpirer C, Szpirer J, Vanvooren P, Tissir F, Kela J, Lallemand F, Hoebee B, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G. The rat genetic and cytogenetic maps Journal of Experimental Animal Science. 41: 38-39. DOI: 10.1016/S0939-8600(00)80025-5 |
0.47 |
|
| 2000 |
Rioux JD, Silverberg MS, Daly MJ, Hillary Steinhart A, McLeod RS, Griffiths AM, Bull SB, Greenberg GR, Cohen Z, Lander ES, Hudson TJ, Siminovitch KA. A genome-wide scan in a canadian inflammatory bowel disease (IBD) population reveals two novel susceptibility loci Gastroenterology. 118: A708. DOI: 10.1016/S0016-5085(00)84962-8 |
0.422 |
|
| 2000 |
Silverberg MS, Daly MJ, Rioux JD, Mcleod RS, Greenberg GR, Cohen Z, Lander ES, Hudson T, Siminovitch KA, Hillary Steinhart A. Effect of diagnostic misclassification on the ability to detect linkage in inflammatory bowel disease (IBD) Gastroenterology. 118: A337. DOI: 10.1016/S0016-5085(00)83445-9 |
0.311 |
|
| 1999 |
Batzoglou S, Berger B, Mesirov J, Lander ES. Sequencing a genome by walking with clone-end sequences: a mathematical analysis. Genome Research. 9: 1163-74. PMID 10613838 DOI: 10.1101/Gr.9.12.1163 |
0.554 |
|
| 1999 |
Pachter L, Batzoglou S, Spitkovsky VI, Banks E, Lander ES, Kleitman DJ, Berger B. A dictionary-based approach for gene annotation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 6: 419-30. PMID 10582576 DOI: 10.1089/106652799318364 |
0.513 |
|
| 1999 |
Klockars T, Holmberg V, Savukoski M, Lander ES, Peltonen L. Transcript identification on the CLN5 region on chromosome 13q22. Human Genetics. 105: 51-6. PMID 10480355 DOI: 10.1007/s004399900069 |
0.339 |
|
| 1999 |
Sidow A, Bulotsky MS, Kerrebrock AW, Birren BW, Altshuler D, Jaenisch R, Johnson KR, Lander ES. A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nature Genetics. 23: 104-7. PMID 10471509 DOI: 10.1038/12709 |
0.479 |
|
| 1999 |
Klaff LS, Koike G, Jiang J, Wang Y, Bieg S, Pettersson A, Lander E, Jacob H, Lernmark Å. BB rat diabetes susceptibility and body weight regulation genes colocalize on Chromosome 2 Mammalian Genome. 10: 883-887. PMID 10441739 DOI: 10.1007/S003359901108 |
0.52 |
|
| 1999 |
Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, Shaw N, Lane CR, Lim EP, Kalyanaraman N, Nemesh J, Ziaugra L, Friedland L, Rolfe A, Warrington J, ... ... Lander ES, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genetics. 22: 231-8. PMID 10391209 DOI: 10.1038/10290 |
0.524 |
|
| 1999 |
Szpirer C, Szpirer J, Van Vooren P, Tissir F, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G. Gene-based anchoring of the rat genetic linkage and cytogenetic maps. Transplantation Proceedings. 31: 1541-3. PMID 10330994 DOI: 10.1016/S0041-1345(99)00030-5 |
0.492 |
|
| 1999 |
Ross RK, Coetzee GA, Pearce CL, Reichardt JK, Bretsky P, Kolonel LN, Henderson BE, Lander E, Altshuler D, Daley G. Androgen metabolism and prostate cancer: establishing a model of genetic susceptibility. European Urology. 35: 355-61. PMID 10325489 DOI: 10.1159/000019909 |
0.505 |
|
| 1999 |
Szpirer C, Szpirer J, Van Vooren P, Tissir F, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G. Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 721-34. PMID 9716657 DOI: 10.1007/S003359900853 |
0.519 |
|
| 1998 |
Rioux JD, Daly MJ, Green T, Stone V, Lander ES, Hudson TJ, Steinhart AH, Bull S, Cohen Z, Greenberg G, Griffiths A, McLeod R, Silverberg M, Williams CN, Siminovitch KA. Absence of linkage between inflammatory bowel disease and selected loci on chromosomes 3, 7, 12, and 16. Gastroenterology. 115: 1062-5. PMID 9797358 DOI: 10.1016/S0016-5085(98)70074-5 |
0.439 |
|
| 1998 |
Rioux JD, Stone VA, Daly MJ, Cargill M, Green T, Nguyen H, Nutman T, Zimmerman PA, Tucker MA, Hudson T, Goldstein AM, Lander E, Lin AY. Familial eosinophilia maps to the cytokine gene cluster on human chromosomal region 5q31-q33 American Journal of Human Genetics. 63: 1086-1094. PMID 9758611 DOI: 10.1086/302053 |
0.518 |
|
| 1998 |
McCarthy MI, Kruglyak L, Lander ES. Sib-pair collection strategies for complex diseases. Genetic Epidemiology. 15: 317-40. PMID 9671984 DOI: 10.1002/(Sici)1098-2272(1998)15:4<317::Aid-Gepi1>3.0.Co;2-# |
0.516 |
|
| 1998 |
Kusumi K, Sun ES, Kerrebrock AW, Bronson RT, Chi DC, Bulotsky MS, Spencer JB, Birren BW, Frankel WN, Lander ES. The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nature Genetics. 19: 274-8. PMID 9662403 DOI: 10.1038/961 |
0.54 |
|
| 1998 |
Brown DM, Matise TC, Koike G, Simon JS, Winer ES, Zangen S, McLaughlin MG, Shiozawa M, Atkinson OS, Hudson JR, Chakravarti A, Lander ES, Jacob HJ. An integrated genetic linkage map of the laboratory rat. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 521-30. PMID 9657848 DOI: 10.1007/S003359900812 |
0.49 |
|
| 1998 |
Altshuler D, Kruglyak L, Lander E. Genetic polymorphisms and disease. The New England Journal of Medicine. 338: 1626. PMID 9606122 DOI: 10.1056/Nejm199805283382214 |
0.685 |
|
| 1998 |
Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R, Ghandour G, Perkins N, Winchester E, Spencer J, Kruglyak L, Stein L, Hsie L, Topaloglou T, Hubbell E, ... ... Lander ES, et al. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science (New York, N.Y.). 280: 1077-82. PMID 9582121 DOI: 10.1126/Science.280.5366.1077 |
0.563 |
|
| 1998 |
Kruglyak L, Lander ES. Faster multipoint linkage analysis using Fourier transforms. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 5: 1-7. PMID 9541867 DOI: 10.1089/Cmb.1998.5.1 |
0.494 |
|
| 1998 |
Bieg S, Koike G, Jiang J, Klaff L, Pettersson A, MacMurray AJ, Jacob HJ, Lander ES, Lernmark A. Genetic isolation of iddm 1 on chromosome 4 in the biobreeding (BB) rat. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 324-6. PMID 9530633 DOI: 10.1007/S003359900759 |
0.447 |
|
| 1998 |
Kuokkanen S, Gschwend M, Rioux JD, Daly MJ, Terwilliger JD, Tienari PJ, Wikström J, Palo J, Stein LD, Hudson TJ, Lander ES, Peltonen L. Genomewide scan of multiple sclerosis in Finnish multiplex families. American Journal of Human Genetics. 61: 1379-87. PMID 9399895 DOI: 10.1086/301637 |
0.375 |
|
| 1998 |
Silverberg M, Steinhart A, McLeod R, Griffiths A, Mirea L, Bull S, Williams C, Greenberg G, Cohen Z, Siminovitch K, Rioux J, Daly M, Green T, Stone V, Hudson T, ... Lander E, et al. Genetic susceptibility in a Canadian inflammatory bowel disease (IBD) population Gastroenterology. 114: A1085. DOI: 10.1016/S0016-5085(98)84414-4 |
0.338 |
|
| 1998 |
Silverberg M, Murphy J, Steinhart A, McLeod R, Griffiths A, Mirea L, Szyda J, Bull S, Williams C, Greenberg G, Cohen Z, Wade J, Siminovitch K, Rioux J, Daly M, ... ... Lander E, et al. Contribution of HLA class II genes to susceptibility to ulcerative colitis (UC) in a Canadian inflammatory bowel disease (IBD) population Gastroenterology. 114: A1085. DOI: 10.1016/S0016-5085(98)84413-2 |
0.342 |
|
| 1997 |
Slonim D, Kruglyak L, Stein L, Lander E. Building human genome maps with radiation hybrids. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 4: 487-504. PMID 9385541 DOI: 10.1089/Cmb.1997.4.487 |
0.555 |
|
| 1997 |
Shi YP, Mohapatra G, Miller J, Hanahan D, Lander E, Gold P, Pinkel D, Gray J. FISH probes for mouse chromosome identification Genomics. 45: 42-47. PMID 9339359 DOI: 10.1006/Geno.1997.4904 |
0.362 |
|
| 1997 |
Sidow A, Bulotsky MS, Kerrebrock AW, Bronson RT, Daly MJ, Reeve MP, Hawkins TL, Birren BW, Jaenisch R, Lander ES. Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature. 389: 722-5. PMID 9338782 DOI: 10.1038/39587 |
0.419 |
|
| 1997 |
Laitinen T, Kauppi P, Ignatius J, Ruotsalainen T, Daly MJ, Kääriäinen H, Kruglyak L, Laitinen H, de la Chapelle A, Lander ES, Laitinen LA, Kere J. Genetic control of serum IgE levels and asthma: linkage and linkage disequilibrium studies in an isolated population. Human Molecular Genetics. 6: 2069-76. PMID 9328470 DOI: 10.1093/Hmg/6.12.2069 |
0.61 |
|
| 1997 |
Kong A, Frigge M, Bell GI, Lander ES, Daly MJ, Cox NJ. Diabetes, dependence, asymptotics, selection and significance. Nature Genetics. 17: 148. PMID 9326932 DOI: 10.1038/Ng1097-148 |
0.307 |
|
| 1997 |
Cormier RT, Hong KH, Halberg RB, Hawkins TL, Richardson P, Mulherkar R, Dove WF, Lander ES. Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis Nature Genetics. 17: 88-91. PMID 9288104 DOI: 10.1038/Ng0997-88 |
0.304 |
|
| 1997 |
Hamilton BA, Smith DJ, Mueller KL, Kerrebrock AW, Bronson RT, van Berkel V, Daly MJ, Kruglyak L, Reeve MP, Nemhauser JL, Hawkins TL, Rubin EM, Lander ES. The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression. Neuron. 18: 711-22. PMID 9182797 DOI: 10.1016/S0896-6273(00)80312-8 |
0.678 |
|
| 1996 |
Daly MJ, Lander ES. The importance of being independent: sib pair analysis in diabetes. Nature Genetics. 14: 131-2. PMID 8841179 DOI: 10.1038/Ng1096-131 |
0.324 |
|
| 1996 |
Mahtani MM, Widén E, Lehto M, Thomas J, McCarthy M, Brayer J, Bryant B, Chan G, Daly M, Forsblom C, Kanninen T, Kirby A, Kruglyak L, Munnelly K, Parkkonen M, ... ... Lander ES, et al. Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nature Genetics. 14: 90-4. PMID 8782826 DOI: 10.1038/Ng0996-90 |
0.603 |
|
| 1996 |
Gschwend M, Levran O, Kruglyak L, Ranade K, Verlander PC, Shen S, Faure S, Weissenbach J, Altay C, Lander ES, Auerbach AD, Botstein D. A locus for Fanconi anemia on 16q determined by homozygosity mapping. American Journal of Human Genetics. 59: 377-84. PMID 8755924 |
0.552 |
|
| 1996 |
Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. Parametric and nonparametric linkage analysis: a unified multipoint approach. American Journal of Human Genetics. 58: 1347-63. PMID 8651312 |
0.517 |
|
| 1996 |
Kruglyak L, Lander ES. Limits on fine mapping of complex traits. American Journal of Human Genetics. 58: 1092-3. PMID 8651271 |
0.475 |
|
| 1996 |
Hamilton BA, Frankel WN, Kerrebrock AW, Hawkins TL, FitzHugh W, Kusumi K, Russell LB, Mueller KL, van Berkel V, Birren BW, Kruglyak L, Lander ES. Disruption of the nuclear hormone receptor RORalpha in staggerer mice. Nature. 379: 736-9. PMID 8602221 DOI: 10.1038/379736A0 |
0.725 |
|
| 1996 |
Dietrich WF, Miller J, Steen R, Merchant MA, Damron-Boles D, Husain Z, Dredge R, Daly MJ, Ingalls KA, O'Connor TJ, Evans CA, DeAngelis MM, Levinson DM, Kruglyak L, Goodman N, ... ... Lander ES, et al. A comprehensive genetic map of the mouse genome Nature. 380: 149-152. PMID 8600386 DOI: 10.1038/380149A0 |
0.65 |
|
| 1996 |
Brown DM, Provoost AP, Daly MJ, Lander ES, Jacob HJ. Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. Nature Genetics. 12: 44-51. PMID 8528250 DOI: 10.1038/Ng0196-44 |
0.546 |
|
| 1996 |
Galli J, Li LS, Glaser A, Ostenson CG, Jiao H, Fakhrai-Rad H, Jacob HJ, Lander ES, Luthman H. Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nature Genetics. 12: 31-7. PMID 8528247 DOI: 10.1038/Ng0196-31 |
0.478 |
|
| 1996 |
Hamilton BA, Frankel WN, Kerrebrock AW, Hawkins TL, FitzHugh W, Kusumi K, Russell LB, Mueller KL, van Berkel V, Birren BW, Kruglyak L, Lander ES. Correction: Disruption of the nuclear hormone receptor RORα in staggerer mice Nature. 381: 346-346. DOI: 10.1038/381346B0 |
0.687 |
|
| 1996 |
Dietrich WF, Miller J, Steen R, Merchant MA, Damron-Boles D, Husain Z, Dredge R, Daly MJ, Ingalls KA, O'Connor TJ, Evans CA, DeAngelis MM, Levinson DM, Kruglyak L, Goodman N, ... ... Lander ES, et al. Correction: A comprehensive genetic map of the mouse genome Nature. 381: 172-172. DOI: 10.1038/381172C0 |
0.605 |
|
| 1995 |
Schork NJ, Krieger JE, Trolliet MR, Franchini KG, Koike G, Krieger EM, Lander ES, Dzau VJ, Jacob HJ. A biometrical genome search in rats reveals the multigenic basis of blood pressure variation Genome Research. 5: 164-172. PMID 9132270 DOI: 10.1101/Gr.5.2.164 |
0.48 |
|
| 1995 |
Hudson TJ, Stein LD, Gerety SS, Ma J, Castle AB, Silva J, Slonim DK, Baptista R, Kruglyak L, Xu SH, Hu X, Colbert AM, Rosenberg C, Reeve-Daly MP, Rozen S, ... ... Lander ES, et al. An STS-based map of the human genome. Science (New York, N.Y.). 270: 1945-54. PMID 8533086 DOI: 10.1126/Science.270.5244.1945 |
0.579 |
|
| 1995 |
Kruglyak L, Daly MJ, Lander ES. Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. American Journal of Human Genetics. 56: 519-27. PMID 7847388 |
0.522 |
|
| 1995 |
Kruglyak L, Lander ES. A nonparametric approach for mapping quantitative trait loci. Genetics. 139: 1421-8. PMID 7768449 |
0.512 |
|
| 1995 |
Kruglyak L, Lander ES. High-resolution genetic mapping of complex traits. American Journal of Human Genetics. 56: 1212-23. PMID 7726179 |
0.559 |
|
| 1995 |
Truett GE, Jacob HJ, Miller J, Drouin G, Bahary N, Smoller JW, Lander ES, Leibel RL. Genetic map of rat Chromosome 5 including the fatty (fa) locus Mammalian Genome. 6: 25-30. PMID 7719022 DOI: 10.1007/Bf00350889 |
0.443 |
|
| 1995 |
Kruglyak L, Lander ES. Complete multipoint sib-pair analysis of qualitative and quantitative traits. American Journal of Human Genetics. 57: 439-54. PMID 7668271 |
0.528 |
|
| 1995 |
Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genetics. 11: 241-7. PMID 7581446 DOI: 10.1038/Ng1195-241 |
0.587 |
|
| 1995 |
Pettersson A, Wilson D, Daniels T, Tobin S, Jacob HJ, Lander ES, Lernmark A. Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes. Journal of Autoimmunity. 8: 493-505. PMID 7492346 DOI: 10.1016/0896-8411(95)90004-7 |
0.435 |
|
| 1995 |
Segre JA, Nemhauser JL, Taylor BA, Nadeau JH, Lander ES. Positional cloning of the nude locus: genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics. 28: 549-59. PMID 7490093 DOI: 10.1006/geno.1995.1187 |
0.302 |
|
| 1994 |
Lisitsyn NA, Segre JA, Kusumi K, Lisitsyn NM, Nadeau JH, Frankel WN, Wigler MH, Lander ES. Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis. Nature Genetics. 6: 57-63. PMID 8136836 DOI: 10.1038/Ng0194-57 |
0.568 |
|
| 1994 |
Hästbacka J, de la Chapelle A, Kaitila I, Sistonen P, Weaver A, Lander E. Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland. Nature Genetics. 2: 204-11. PMID 1345170 DOI: 10.1038/Ng1192-204 |
0.38 |
|
| 1993 |
Kusumi K, Smith JS, Segre JA, Koos DS, Lander ES. Construction of a large-insert yeast artificial chromosome library of the mouse genome Mammalian Genome. 4: 391-392. PMID 8358173 DOI: 10.1007/BF00360591 |
0.582 |
|
| 1993 |
Lehesjoki AE, Koskiniemi M, Norio R, Tirrito S, Sistonen P, Lander E, de la Chapelle A. Localization of the EPM1 gene for progressive myoclonus epilepsy on chromosome 21: linkage disequilibrium allows high resolution mapping. Human Molecular Genetics. 2: 1229-34. PMID 8104628 DOI: 10.1093/Hmg/2.8.1229 |
0.367 |
|
| 1993 |
Jacob HJ, Pettersson A, Wilson D, Mao Y, Lernmark A, Lander ES. Genetic dissection of autoimmune type I diabetes in the BB rat. Nature Genetics. 2: 56-60. PMID 1303251 DOI: 10.1038/Ng0992-56 |
0.505 |
|
| 1992 |
Dzau VJ, Jacob HJ, Lindpainter K, Ganten D, Lander ES. Genetic mapping in hypertension. Journal of Vascular Surgery. 15: 930. PMID 1578573 DOI: 10.1016/0741-5214(92)90757-Y |
0.45 |
|
| 1992 |
Goff DJ, Galvin K, Katz H, Westerfield M, Lander ES, Tabin CJ. Identification of polymorphic simple sequence repeats in the genome of the zebrafish. Genomics. 14: 200-2. PMID 1427829 DOI: 10.1016/S0888-7543(05)80309-X |
0.311 |
|
| 1991 |
Jacob JJ, Lindpaintner K, Lincoln SE, Kusumi K, Bunker RK, Mao YP, Ganten D, Dzau VJ, Lander ES. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat Cell. 67: 213-224. PMID 1655275 DOI: 10.1016/0092-8674(91)90584-L |
0.554 |
|
| 1988 |
Chang C, Bowman JL, DeJohn AW, Lander ES, Meyerowitz EM. Restriction fragment length polymorphism linkage map for Arabidopsis thaliana Proceedings of the National Academy of Sciences of the United States of America. 85: 6856-6860. PMID 2901107 DOI: 10.1073/Pnas.85.18.6856 |
0.53 |
|
| 1987 |
Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newberg LA, Newburg L. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics. 1: 174-81. PMID 3692487 DOI: 10.1016/0888-7543(87)90010-3 |
0.402 |
|
| 1987 |
Barker D, Green P, Knowlton R, Schumm J, Lander E, Oliphant A, Willard H, Akots G, Brown V, Gravius T. Genetic linkage map of human chromosome 7 with 63 DNA markers. Proceedings of the National Academy of Sciences of the United States of America. 84: 8006-8010. PMID 2891136 DOI: 10.1073/Pnas.84.22.8006 |
0.359 |
|
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