Kimberly A. Scearce-Levie - Publications

Affiliations: 
Genentech, Inc., San Francisco, CA, United States 
Area:
behavioral neuroscience, neurodegeneration

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, Lin CC, Davis S, Ha C, Leung AW, Nguyen H, ... ... Scearce-Levie K, et al. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Molecular Neurodegeneration. 17: 41. PMID 35690868 DOI: 10.1186/s13024-022-00547-7  0.712
2021 Ayalon G, Lee SH, Adolfsson O, Foo-Atkins C, Atwal JK, Blendstrup M, Booler H, Bravo J, Brendza R, Brunstein F, Chan R, Chandra P, Couch JA, Datwani A, Demeule B, ... ... Scearce-Levie K, et al. Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease. Science Translational Medicine. 13. PMID 33980574 DOI: 10.1126/scitranslmed.abb2639  0.351
2020 Scearce-Levie K, Sanchez PE, Lewcock JW. Leveraging preclinical models for the development of Alzheimer disease therapeutics. Nature Reviews. Drug Discovery. 19: 447-462. PMID 32612262 DOI: 10.1038/S41573-020-0065-9  0.4
2020 Hanson JE, Ma K, Elstrott J, Weber M, Saillet S, Khan AS, Simms J, Liu B, Kim TA, Yu GQ, Chen Y, Wang TM, Jiang Z, Liederer BM, Deshmukh G, ... ... Scearce-Levie K, et al. GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. Cell Reports. 30: 381-396.e4. PMID 31940483 DOI: 10.1016/J.Celrep.2019.12.030  0.675
2018 Dominguez SL, Hegde GV, Hanson JE, Xiang H, Mandikian D, Boswell CA, Chiu C, Wu Y, Tsai SP, Fleck D, Weber M, Ngu H, Scearce-Levie K, Jackson EL. Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice. Scientific Reports. 8: 8239. PMID 29844389 DOI: 10.1038/s41598-018-26492-4  0.417
2017 Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, ... ... Scearce-Levie K, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Science Translational Medicine. 9. PMID 28814543 DOI: 10.1126/Scitranslmed.Aag0394  0.406
2017 Wong K, Noubade R, Manzanillo P, Ota N, Foreman O, Hackney JA, Friedman BA, Pappu R, Scearce-Levie K, Ouyang W. Mice deficient in NRROS show abnormal microglial development and neurological disorders. Nature Immunology. PMID 28459434 DOI: 10.1038/ni.3743  0.39
2017 Weber M, Wu T, Meilandt WJ, Dominguez SL, Solanoy HO, Maloney JA, Ngu H, Baca M, Kung C, Lima L, Earr TK, Fleck D, Shields SD, Forrest WF, Foreman O, ... ... Scearce-Levie K, et al. BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats. Scientific Reports. 7: 44249. PMID 28281673 DOI: 10.1038/Srep44249  0.404
2017 Villemure E, Volgraf M, Jiang Y, Wu G, Ly CQ, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Lupardus PJ, Wallweber HJ, Liederer BM, Deshmukh G, Plise E, ... ... Scearce-Levie K, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. Acs Medicinal Chemistry Letters. 8: 84-89. PMID 28105280 DOI: 10.1021/Acsmedchemlett.6B00388  0.312
2016 Ertürk A, Mentz S, Stout EE, Hedehus M, Dominguez SL, Neumaier L, Krammer F, Llovera G, Srinivasan K, Hansen DV, Liesz A, Scearce-Levie KA, Sheng M. Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9962-75. PMID 27656033 DOI: 10.1523/Jneurosci.1898-15.2016  0.306
2016 Lee SH, Le Pichon CE, Adolfsson O, Gafner V, Pihlgren M, Lin H, Solanoy H, Brendza R, Ngu H, Foreman O, Chan R, Ernst JA, DiCara D, Hotzel I, Srinivasan K, ... ... Scearce-Levie K, et al. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Reports. PMID 27475227 DOI: 10.1016/J.Celrep.2016.06.099  0.39
2016 Lu Y, Hoyte K, Montgomery WH, Luk W, He D, Meilandt WJ, Yu Zuchero YJ, Atwal JK, Scearce-Levie K, Watts RJ, DeForge LE. Characterization of a sensitive mouse Aβ40 PD biomarker assay for Alzheimer's disease drug development in wild-type mice. Bioanalysis. PMID 27094761 DOI: 10.4155/Bio-2016-0003  0.493
2016 Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, ... ... Scearce-Levie K, et al. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. Journal of Medicinal Chemistry. PMID 26919761 DOI: 10.1021/Acs.Jmedchem.5B02010  0.304
2016 Lo SC, Scearce-Levie K, Sheng M. Characterization of Social Behaviors in caspase-3 deficient mice. Scientific Reports. 6: 18335. PMID 26783106 DOI: 10.1038/srep18335  0.317
2015 Lo SC, Wang Y, Weber M, Larson JL, Scearce-Levie K, Sheng M. Caspase-3 deficiency results in disrupted synaptic homeostasis and impaired attention control. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2118-32. PMID 25653368 DOI: 10.1523/JNEUROSCI.3280-14.2015  0.361
2015 Patel S, Cohen F, Dean BJ, De La Torre K, Deshmukh G, Estrada AA, Ghosh AS, Gibbons P, Gustafson A, Huestis MP, Le Pichon CE, Lin H, Liu W, Liu X, Liu Y, ... ... Scearce-Levie K, et al. Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models. Journal of Medicinal Chemistry. 58: 401-18. PMID 25341110 DOI: 10.1021/Jm5013984  0.653
2015 Lee S, Le Pichon C, Adolfsson O, Gafner V, Pihlgren M, Lin H, Solanoy H, Brendza R, Ngu H, Foreman O, Chan R, Ernst J, Dicara D, Hotzel I, Srinivasan K, ... ... Scearce-Levie K, et al. P2-054: Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology Alzheimer's & Dementia. 11: P503-P504. DOI: 10.1016/J.Jalz.2015.06.591  0.311
2014 Thomas AA, Hunt KW, Newhouse B, Watts RJ, Liu X, Vigers G, Smith D, Rhodes SP, Brown KD, Otten JN, Burkard M, Cox AA, Geck Do MK, Dutcher D, Rana S, ... ... Scearce-Levie K, et al. 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 10112-29. PMID 25411915 DOI: 10.1021/Jm5015132  0.311
2014 Yu YJ, Atwal JK, Zhang Y, Tong RK, Wildsmith KR, Tan C, Bien-Ly N, Hersom M, Maloney JA, Meilandt WJ, Bumbaca D, Gadkar K, Hoyte K, Luk W, Lu Y, ... ... Scearce-Levie K, et al. Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154. PMID 25378646 DOI: 10.1126/Scitranslmed.3009835  0.323
2014 Hanson JE, Meilandt WJ, Gogineni A, Reynen P, Herrington J, Weimer RM, Scearce-Levie K, Zhou Q. Chronic GluN2B antagonism disrupts behavior in wild-type mice without protecting against synapse loss or memory impairment in Alzheimer's disease mouse models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8277-88. PMID 24920631 DOI: 10.1523/JNEUROSCI.5106-13.2014  0.506
2014 Kallop DY, Meilandt WJ, Gogineni A, Easley-Neal C, Wu T, Jubb AM, Yaylaoglu M, Shamloo M, Tessier-Lavigne M, Scearce-Levie K, Weimer RM. A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6425-37. PMID 24806669 DOI: 10.1523/Jneurosci.4963-13.2014  0.488
2014 Thomas AA, Hunt KW, Volgraf M, Watts RJ, Liu X, Vigers G, Smith D, Sammond D, Tang TP, Rhodes SP, Metcalf AT, Brown KD, Otten JN, Burkard M, Cox AA, ... ... Scearce-Levie K, et al. Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system. Journal of Medicinal Chemistry. 57: 878-902. PMID 24397738 DOI: 10.1021/Jm401635N  0.323
2014 Shin YG, Hamm L, Murakami S, Buirst K, Buonarati MH, Cox A, Regal K, Hunt KW, Scearce-Levie K, Watts RJ, Liu X. Qualification and application of a liquid chromatography-tandem mass spectrometric method for the determination of human Aβ1-40 and Aβ1-42 peptides in transgenic mouse plasma using micro-elution solid phase extraction. Archives of Pharmacal Research. 37: 636-44. PMID 23888333 DOI: 10.1007/S12272-013-0215-2  0.345
2013 Chan BK, Estrada AA, Chen H, Atherall J, Baker-Glenn C, Beresford A, Burdick DJ, Chambers M, Dominguez SL, Drummond J, Gill A, Kleinheinz T, Le Pichon CE, Medhurst AD, Liu X, ... ... Scearce-Levie K, et al. Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 4: 85-90. PMID 24900567 DOI: 10.1021/Ml3003007  0.31
2013 Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, et al. Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration. The Journal of Experimental Medicine. 210: 2553-67. PMID 24166713 DOI: 10.1084/Jem.20122832  0.393
2013 Hanson JE, La H, Plise E, Chen YH, Ding X, Hanania T, Sabath EV, Alexandrov V, Brunner D, Leahy E, Steiner P, Liu L, Scearce-Levie K, Zhou Q. SAHA enhances synaptic function and plasticity in vitro but has limited brain availability in vivo and does not impact cognition. Plos One. 8: e69964. PMID 23922875 DOI: 10.1371/journal.pone.0069964  0.376
2013 Le Pichon CE, Dominguez SL, Solanoy H, Ngu H, Lewin-Koh N, Chen M, Eastham-Anderson J, Watts R, Scearce-Levie K. EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS. Plos One. 8: e62342. PMID 23638043 DOI: 10.1371/Journal.Pone.0062342  0.358
2013 Hanson JE, Weber M, Meilandt WJ, Wu T, Luu T, Deng L, Shamloo M, Sheng M, Scearce-Levie K, Zhou Q. GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1221-33. PMID 23340518 DOI: 10.1038/Npp.2013.19  0.428
2013 Meilandt W, Atwal J, Gadkar K, Hoyte K, Luk W, Lu Y, Watts R, Scearce-Levie K. Modest reductions in BACE1 activity significantly reduce beta-amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease Alzheimers & Dementia. 9: 504. DOI: 10.1016/J.Jalz.2013.05.1048  0.397
2012 Meilandt W, Atwal J, Solanoy H, Hoyte K, Luk W, Lu Y, Watts R, Scearce-Levie K. Role of BACE1 and BACE2 in the production of endogenous mouse Aß Alzheimers & Dementia. 8: 193. DOI: 10.1016/J.Jalz.2012.05.528  0.307
2011 Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, et al. Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies. Alzheimer's Research & Therapy. 3: 28. PMID 21943025 DOI: 10.1186/Alzrt90  0.35
2011 Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, et al. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell. 145: 863-74. PMID 21640374 DOI: 10.1016/J.Cell.2011.05.020  0.414
2011 Atwal JK, Chen Y, Chiu C, Mortensen DL, Meilandt WJ, Liu Y, Heise CE, Hoyte K, Luk W, Lu Y, Peng K, Wu P, Rouge L, Zhang Y, Lazarus RA, ... Scearce-Levie K, et al. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Science Translational Medicine. 3: 84ra43. PMID 21613622 DOI: 10.1126/Scitranslmed.3002254  0.417
2011 Scearce-Levie K. Monitoring spatial learning and memory in Alzheimer's disease mouse models using the Morris Water Maze. Methods in Molecular Biology (Clifton, N.J.). 670: 191-205. PMID 20967592 DOI: 10.1007/978-1-60761-744-0_14  0.382
2010 Tong Y, Xu Y, Scearce-Levie K, Ptácek LJ, Fu YH. COL25A1 triggers and promotes Alzheimer's disease-like pathology in vivo. Neurogenetics. 11: 41-52. PMID 19548013 DOI: 10.1007/s10048-009-0201-5  0.447
2009 Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu GQ, Mucke L. Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1977-86. PMID 19228952 DOI: 10.1523/JNEUROSCI.2984-08.2009  0.765
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature Neuroscience. 11: 1311-8. PMID 18931664 DOI: 10.1038/Nn.2213  0.819
2008 Zhong N, Scearce-Levie K, Ramaswamy G, Weisgraber KH. Apolipoprotein E4 domain interaction: synaptic and cognitive deficits in mice. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 179-92. PMID 18631967 DOI: 10.1016/j.jalz.2008.01.006  0.374
2008 Meilandt WJ, Yu GQ, Chin J, Roberson ED, Palop JJ, Wu T, Scearce-Levie K, Mucke L. Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5007-17. PMID 18463254 DOI: 10.1523/Jneurosci.0590-08.2008  0.815
2008 Scearce-Levie K, Roberson ED, Gerstein H, Cholfin JA, Mandiyan VS, Shah NM, Rubenstein JL, Mucke L. Abnormal social behaviors in mice lacking Fgf17. Genes, Brain, and Behavior. 7: 344-54. PMID 17908176 DOI: 10.1111/j.1601-183X.2007.00357.x  0.707
2008 Cheng JS, Cheng IH, Kim DH, Wu T, Tesseur I, Wyss-Coray T, Bonaldo P, Scearce-Levie K, Mucke L. P1-413: Collagen VI protects neurons against amyloid-beta toxicity Alzheimer's & Dementia. 4: T340-T340. DOI: 10.1016/J.Jalz.2008.05.995  0.728
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu G, Zhou Y, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. O4-02-03: Phospholipase A2 reduction ameliorates cognitive deficits in mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T186-T187. DOI: 10.1016/J.Jalz.2008.05.511  0.757
2007 Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. The Journal of Biological Chemistry. 282: 23818-28. PMID 17548355 DOI: 10.1074/Jbc.M701078200  0.783
2007 Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). 316: 750-4. PMID 17478722 DOI: 10.1126/Science.1141736  0.803
2007 Sweger EJ, Casper KB, Scearce-Levie K, Conklin BR, McCarthy KD. Development of hydrocephalus in mice expressing the G(i)-coupled GPCR Ro1 RASSL receptor in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2309-17. PMID 17329428 DOI: 10.1523/Jneurosci.4565-06.2007  0.437
2006 Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, Puoliväli J, Scearce-Levie K, Masliah E, Mucke L. Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5167-79. PMID 16687508 DOI: 10.1523/Jneurosci.0482-06.2006  0.713
2006 Meilandt WJ, Wu T, Yu G, Scearce-Levie K, Mucke L. P4-314: Overexpression of neprilysin decreases neuronal and behavioral impairments in human amyloid precursor protein transgenic mice Alzheimer's & Dementia. 2: S609-S609. DOI: 10.1016/j.jalz.2006.05.2055  0.662
2006 Esposito L, Yan F, Yu G, Wang X, Puolivali J, Scearce-Levie K, Masliah E, Mucke L. P3-359: Reduction of mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology in human amyloid precursor protein transgenic mice Alzheimer's & Dementia. 2: S480-S480. DOI: 10.1016/J.Jalz.2006.05.1629  0.66
2006 Roberson ED, Scearce-Levie K, Yan F, Yu G, Mucke L. O2-04-05: Reducing endogenous tau prevents APP/Aβ-induced deficits in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 2: S38-S38. DOI: 10.1016/j.jalz.2006.05.133  0.653
2005 Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, Mucke L. Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9694-703. PMID 16237174 DOI: 10.1523/Jneurosci.2980-05.2005  0.796
2003 Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10966-71. PMID 12939405 DOI: 10.1073/Pnas.1434398100  0.751
2003 Compan V, Scearce-Levie K, Crosson C, Daszuta A, Hen R. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. The European Journal of Neuroscience. 18: 383-90. PMID 12887420 DOI: 10.1046/J.1460-9568.2003.02767.X  0.71
2000 Castanon N, Scearce-Levie K, Lucas JJ, Rocha B, Hen R. Modulation of the effects of cocaine by 5-HT1B receptors: a comparison of knockouts and antagonists. Pharmacology, Biochemistry, and Behavior. 67: 559-66. PMID 11164086 DOI: 10.1016/S0091-3057(00)00389-0  0.443
2000 Belzung C, Scearce-Levie K, Barreau S, Hen R. Absence of cocaine-induced place conditioning in serotonin 1B receptor knock-out mice. Pharmacology, Biochemistry, and Behavior. 66: 221-5. PMID 10837864 DOI: 10.1016/S0091-3057(00)00238-0  0.466
2000 Dulawa SC, Scearce-Levie KA, Hen R, Geyer MA. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology. 149: 306-12. PMID 10823412 DOI: 10.1007/s002130000373  0.547
1999 Scearce-Levie K, Chen JP, Gardner E, Hen R. 5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders. Annals of the New York Academy of Sciences. 868: 701-15. PMID 10414358 DOI: 10.1111/j.1749-6632.1999.tb11350.x  0.511
1999 Scearce-Levie K, Viswanathan SS, Hen R. Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology. 141: 154-61. PMID 9952039 DOI: 10.1007/s002130050819  0.541
1998 Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. 5-HT1B receptor modulation of prepulse inhibition: recent findings in wild-type and 5-HT1B knockout mice. Annals of the New York Academy of Sciences. 861: 79-84. PMID 9928242 DOI: 10.1111/j.1749-6632.1998.tb10176.x  0.532
1998 Lucas JJ, Yamamoto A, Scearce-Levie K, Saudou F, Hen R. Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5537-44. PMID 9651234 DOI: 10.1523/Jneurosci.18-14-05537.1998  0.741
1998 Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259  0.516
1997 Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology. 132: 125-34. PMID 9266609 DOI: 10.1007/s002130050328  0.578
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