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Amanda R. Wasylishen, Ph.D. - Publications

Affiliations: 
2012 University of Toronto, Toronto, ON, Canada 
Area:
General Biophysics
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29/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Moyer SM, Wasylishen AR, Qi Y, Fowlkes N, Su X, Lozano G. p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 32900967 DOI: 10.1073/Pnas.2008474117  0.392
2020 Wasylishen AR, Sun C, Moyer SM, Qi Y, Chau GP, Aryal NK, McAllister F, Kim MP, Barton MC, Estrella JS, Su X, Lozano G. Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo. Science Advances. 6: eaba8415. PMID 32821827 DOI: 10.1126/Sciadv.Aba8415  0.403
2020 Wasylishen AR, Sun C, Chau GP, Qi Y, Su X, Kim MP, Estrella JS, Lozano G. Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 32156729 DOI: 10.1073/Pnas.1920017117  0.327
2020 El Beaino M, Liu J, Wasylishen AR, Pourebrahim R, Migut A, Bessellieu BJ, Huang K, Lin PP. Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells. Bmc Cancer. 20: 3. PMID 31898537 DOI: 10.1186/S12885-019-6465-8  0.34
2019 Pant V, Xiong S, Wasylishen AR, Larsson CA, Aryal NK, Chau G, Tailor RC, Lozano G. Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31409715 DOI: 10.1073/Pnas.1909550116  0.302
2019 Samdani RT, Wasylishen AR, Halperin DM, Dasari A, Yao JC, Rashid A, Estrella JS. Loss of Menin Expression by Immunohistochemistry in Pancreatic Neuroendocrine Tumors: Comparison Between Primary and Metastatic Tumors. Pancreas. PMID 30946241 DOI: 10.1097/Mpa.0000000000001274  0.32
2019 Aryal NK, Pant V, Wasylishen AR, Rimel B, Baseler L, El-Naggar AK, Mutch DG, Goodfellow PJ, Arur S, Lozano G. Dicer1 phospho-mimetic promotes tumor progression and dissemination. Cancer Research. PMID 30914430 DOI: 10.1158/0008-5472.Can-18-2460  0.403
2019 Ding J, Li X, Zhang C, Gao F, Wu S, Wasylishen A, Baggerly K, Lozano G, Koul D, Yung A. CBMT-32. EGFR SUPPRESSES p53 FUNCTION THROUGH DNA-PKcs BINDING TO p53: NOVEL CROSSTALK BETWEEN EGFR AND TP53 IN GLIOBLASTOMA Neuro-Oncology. 21: vi40-vi40. DOI: 10.1093/Neuonc/Noz175.154  0.329
2018 Aryal NK, Pant V, Wasylishen AR, Parker-Thornburg J, Baseler L, El-Naggar AK, Liu B, Kalia A, Lozano G, Arur S. Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30593561 DOI: 10.1073/Pnas.1814377116  0.309
2018 Wasylishen AR, Estrella JS, Pant V, Chau GP, Lozano G. Daxx Functions are p53-independent In Vivo. Molecular Cancer Research : McR. PMID 29903771 DOI: 10.1158/1541-7786.Mcr-18-0281  0.386
2018 Tonnessen-Murray C, Ungerleider NA, Rao SG, Wasylishen AR, Frey WD, Jackson JG. p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer. Translational Oncology. 11: 930-940. PMID 29852458 DOI: 10.1016/J.Tranon.2018.05.003  0.442
2017 Aryal NK, Wasylishen AR, Pant V, Riley-Croce M, Lozano G. Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53. Oncotarget. 8: 103996-104006. PMID 29262616 DOI: 10.18632/Oncotarget.22087  0.346
2016 Wasylishen AR, Lozano G. Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End. Cold Spring Harbor Perspectives in Medicine. PMID 27329033 DOI: 10.1101/Cshperspect.A026211  0.417
2016 Li L, Liang S, Wasylishen AR, Zhang Y, Yang X, Zhou B, Shan L, Han X, Mu T, Wang G, Xiong S. PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway. Oncotarget. PMID 26933804 DOI: 10.18632/Oncotarget.7694  0.45
2015 Lourenco C, Wasylishen A, Chan-Seng-Yue M, Bros C, Dingar D, Tu W, Kalkat M, Chan P, Mullen P, Raught B, Boutros P, Penn L. Abstract A10: The myc post-translational landscape: How novel gain-of-function mutants are revealing new stability and functional regulatory systems Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A10  0.631
2015 Kalkat M, Chan P, Wasylishen AR, Srikumar T, Kim SS, Ponzielli R, Bazett-Jones DP, Raught B, Penn LZ. Abstract A08: Identification of c-MYC SUMOylation by mass spectrometry Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A08  0.64
2014 Kalkat M, Chan PK, Wasylishen AR, Srikumar T, Kim SS, Ponzielli R, Bazett-Jones DP, Raught B, Penn LZ. Identification of c-MYC SUMOylation by mass spectrometry. Plos One. 9: e115337. PMID 25522242 DOI: 10.1371/Journal.Pone.0115337  0.628
2014 Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, et al. Pla2g16 phospholipase mediates gain-of-function activities of mutant p53. Proceedings of the National Academy of Sciences of the United States of America. 111: 11145-50. PMID 25024203 DOI: 10.1073/Pnas.1404139111  0.34
2014 Goard CA, Chan-Seng-Yue M, Mullen PJ, Quiroga AD, Wasylishen AR, Clendening JW, Sendorek DH, Haider S, Lehner R, Boutros PC, Penn LZ. Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells. Breast Cancer Research and Treatment. 143: 301-12. PMID 24337703 DOI: 10.1007/S10549-013-2800-Y  0.703
2014 Wasylishen AR, Kalkat M, Kim SS, Pandyra A, Chan PK, Oliveri S, Sedivy E, Konforte D, Bros C, Raught B, Penn LZ. MYC activity is negatively regulated by a C-terminal lysine cluster. Oncogene. 33: 1066-72. PMID 23435422 DOI: 10.1038/Onc.2013.36  0.656
2014 Wasylishen AR, Lozano G. Abstract 3917: Understanding the mechanisms driving pancreatic neuroendocrine tumorigenesis Cancer Research. 74: 3917-3917. DOI: 10.1158/1538-7445.Am2014-3917  0.399
2013 Wasylishen AR, Chan-Seng-Yue M, Bros C, Dingar D, Tu WB, Kalkat M, Chan PK, Mullen PJ, Huang L, Meyer N, Raught B, Boutros PC, Penn LZ. MYC phosphorylation at novel regulatory regions suppresses transforming activity. Cancer Research. 73: 6504-15. PMID 24030976 DOI: 10.1158/0008-5472.Can-12-4063  0.642
2011 Wasylishen AR, Stojanova A, Oliveri S, Rust AC, Schimmer AD, Penn LZ. New model systems provide insights into Myc-induced transformation. Oncogene. 30: 3727-34. PMID 21441954 DOI: 10.1038/Onc.2011.88  0.63
2011 Kalkat M, Wasylishen AR, Kim SS, Penn L. More than MAX: Discovering the Myc interactome. Cell Cycle (Georgetown, Tex.). 10: 374-5. PMID 21270515 DOI: 10.4161/Cc.10.3.14645  0.582
2011 Mullen PJ, Goard CA, Wasylishen AR, Pandyra A, Penn LZ. Abstract C165: Breast cancer, statins, and 3-D cell culture. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C165  0.705
2010 Wasylishen AR, Penn LZ. Myc: the beauty and the beast. Genes & Cancer. 1: 532-41. PMID 21779457 DOI: 10.1177/1947601910378024  0.579
2010 Luoto KR, Meng AX, Wasylishen AR, Zhao H, Coackley CL, Penn LZ, Bristow RG. Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair. Cancer Research. 70: 8748-59. PMID 20940401 DOI: 10.1158/0008-5472.Can-10-0944  0.625
2010 Wong WW, Boutros PC, Wasylishen AR, Guckert KD, O'Brien EM, Griffiths R, Martirosyan AR, Bros C, Jurisica I, Langler RF, Penn LZ. Characterization of the apoptotic response of human leukemia cells to organosulfur compounds. Bmc Cancer. 10: 351. PMID 20598143 DOI: 10.1186/1471-2407-10-351  0.61
2008 Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, et al. Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Research. 68: 6688-97. PMID 18701493 DOI: 10.1158/0008-5472.Can-07-6833  0.576
Low-probability matches (unlikely to be authored by this person)
2020 Wasylishen AR, Sun C, Moyer SM, Qi Y, Chau GP, Aryal NK, McAllister F, Kim MP, Barton MC, Estrella JS, Su X, Lozano G. Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo Science Advances. 6: eaba8415. DOI: 10.1126/sciadv.aba8415  0.296
2021 Kim MP, Li X, Deng J, Zhang Y, Dai B, Allton KL, Hughes TG, Siangco C, Augustine JJ, Kang Y, McDaniel JM, Xiong S, Koay EJ, McAllister F, Bristow CA, ... ... Wasylishen AR, et al. Oncogenic KRAS recruits an expansive transcriptional network through mutant p53 to drive pancreatic cancer metastasis. Cancer Discovery. PMID 33839689 DOI: 10.1158/2159-8290.CD-20-1228  0.268
2017 Ding J, Li X, Wasylishen A, Gao F, Zhao Y, Baggerly K, Lozano G, Koul D, Yung WKA. CBIO-02. AMPLIFIED EGFR DRIVES TUMORIGENESIS IN TP53 WILD TYPE GLIOBLASTOMA THROUGH INHIBITION OF p53 FUNCTION BY DNA-PK/p53 BINDING Neuro-Oncology. 19: vi33-vi33. DOI: 10.1093/Neuonc/Nox168.125  0.268
2018 Aryal NK, Wasylishen AR, Lozano G. CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo. Cell Death & Disease. 9: 1099. PMID 30368519 DOI: 10.1038/S41419-018-1146-0  0.248
2022 Sun C, Estrella JS, Whitley EM, Chau GP, Lozano G, Wasylishen AR. Mouse modeling provides insights into Daxx and Atrx tumor suppressive mechanisms in the endocrine pancreas. Disease Models & Mechanisms. PMID 35976056 DOI: 10.1242/dmm.049552  0.237
2021 Fahrmann JF, Wasylishen AR, Pieterman CRC, Irajizad E, Vykoukal J, Murage E, Wu R, Dennison JB, Krishna H, Peterson CB, Lozano G, Zhao H, Do KA, Halperin DM, Agarwal SK, et al. A blood-based polyamine signature associated with MEN1 duodenopancreatic neuroendocrine tumor progression. The Journal of Clinical Endocrinology and Metabolism. PMID 34318891 DOI: 10.1210/clinem/dgab554  0.193
2008 Caldwell SL, Langler RF, Ryan DA, Wasylishen AR. Synthesis of the first α-mercaptoketal and an antifungal ketodisulfide Journal of Sulfur Chemistry. 29: 163-170. DOI: 10.1080/17415990701870565  0.184
2023 Fahrmann JF, Wasylishen AR, Pieterman CRC, Irajizad E, Vykoukal J, Wu R, Dennison JB, Peterson CB, Zhao H, Do KA, Halperin DM, Agarwal SK, Blau JE, Jha S, Rivero JD, et al. Blood-based proteomic signatures associated with MEN1-related Duodenopancreatic Neuroendocrine Tumor Progression. The Journal of Clinical Endocrinology and Metabolism. PMID 37307230 DOI: 10.1210/clinem/dgad315  0.154
2022 Ding J, Li X, Khan S, Zhang C, Gao F, Sen S, Wasylishen AR, Zhao Y, Lozano G, Koul D, Yung WKA. EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a non-canonical regulatory axis between EGFR and wild-type p53 in glioblastoma. Neuro-Oncology. PMID 35474131 DOI: 10.1093/neuonc/noac105  0.145
2023 Sun C, Qi Y, Fowlkes N, Lazic N, Su X, Lozano G, Wasylishen AR. The histone chaperone function of Daxx is dispensable for embryonic development. Cell Death & Disease. 14: 565. PMID 37633949 DOI: 10.1038/s41419-023-06089-0  0.136
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