| Year |
Citation |
Score |
| 2020 |
Fullenkamp C, Hsu YP, Quardokus E, Zhao G, Bewley CA, VanNieuwenhze MS, Sulikowski GA. Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis. Journal of the American Chemical Society. PMID 32866011 DOI: 10.1021/Jacs.0C04917 |
0.355 |
|
| 2020 |
Kim CK, Wang D, Bokesch HR, Fuller RW, Smith E, Henrich CJ, Durrant DE, Morrison DK, Bewley CA, Gustafson KR. Swinhopeptolides A and B: Cyclic Depsipeptides from the Sponge That Inhibit Ras/Raf Interaction. Journal of Natural Products. PMID 32191460 DOI: 10.1021/Acs.Jnatprod.0C00136 |
0.367 |
|
| 2020 |
Liu HB, Imler GH, Baldridge KK, O'Connor RD, Siegel JS, Deschamps JR, Bewley CA. X-ray crystallography and unexpected chiroptical properties reassign the configuration of haliclonadiamine. Journal of the American Chemical Society. PMID 31986017 DOI: 10.1021/Jacs.9B12926 |
0.323 |
|
| 2019 |
Davison JR, Bewley CA. Antimicrobial Chrysophaentin Analogs Identified from Laboratory Cultures of the Marine Microalga Chrysophaeum taylorii. Journal of Natural Products. PMID 30623657 DOI: 10.1021/Acs.Jnatprod.8B00858 |
0.346 |
|
| 2018 |
Zhou T, Zheng A, Baxa U, Chuang GY, Georgiev IS, Kong R, O'Dell S, Shahzad-Ul-Hussan S, Shen CH, Tsybovsky Y, Bailer RT, Gift SK, Louder MK, McKee K, Rawi R, ... Bewley CA, et al. A Neutralizing Antibody Recognizing Primarily N-linked Glycan Targets the Silent Face of the HIV Envelope. Immunity. PMID 29548671 DOI: 10.1016/J.Immuni.2018.02.013 |
0.343 |
|
| 2017 |
Liu HB, Lauro G, O'Connor RD, Lohith K, Kelly M, Colin P, Bifulco G, Bewley CA. Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge. Journal of Natural Products. PMID 28837335 DOI: 10.1021/Acs.Jnatprod.7B00452 |
0.366 |
|
| 2017 |
Bobyk KD, Mandadapu SR, Lohith K, Guzzo C, Bhargava A, Lusso P, Bewley CA. Design of HIV co-receptor derived peptides that inhibit viral entry at submicromolar concentrations. Molecular Pharmaceutics. PMID 28494151 DOI: 10.1021/Acs.Molpharmaceut.7B00155 |
0.407 |
|
| 2017 |
Davison JR, Lohith KM, Wang X, Bobyk K, Mandadapu SR, Lee SL, Cencic R, Nelson J, Simpkins S, Frank KM, Pelletier J, Myers CL, Piotrowski J, Smith HE, Bewley CA. A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter. Antimicrobial Agents and Chemotherapy. PMID 28373194 DOI: 10.1128/Aac.02635-16 |
0.353 |
|
| 2017 |
Shahzad-Ul-Hussan S, Sastry M, Lemmin T, Soto C, Loesgen S, Scott DA, Davison JR, O'Connor R, Kwong PD, Bewley CA. NMR insights into the conformational properties of Man-9 and its recognition by two HIV binding proteins. Chembiochem : a European Journal of Chemical Biology. PMID 28166380 DOI: 10.1002/Cbic.201600665 |
0.386 |
|
| 2016 |
Melander RJ, Liu HB, Stephens MD, Bewley CA, Melander C. Marine sponge alkaloids as a source of anti-bacterial adjuvants. Bioorganic & Medicinal Chemistry Letters. PMID 27876320 DOI: 10.1016/J.Bmcl.2016.11.018 |
0.342 |
|
| 2016 |
Lusvarghi S, Bewley CA. Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential. Viruses. 8. PMID 27783038 DOI: 10.3390/V8100296 |
0.384 |
|
| 2016 |
Lusvarghi S, Lohith KM, Morin-Leisk J, Ghirlando R, Hinshaw JE, Bewley CA. Binding site geometry and subdomain valency control effects of neutralizing lectins on HIV-1 viral particles. Acs Infectious Diseases. PMID 27669574 DOI: 10.1021/Acsinfecdis.6B00139 |
0.359 |
|
| 2016 |
Liu H, Lohith K, Rosario M, Pulliam TH, O'Connor RD, Bell LJ, Bewley CA. Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity. Journal of Natural Products. PMID 27399938 DOI: 10.1021/Acs.Jnatprod.6B00229 |
0.384 |
|
| 2016 |
Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, ... Bewley CA, et al. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. Cell. PMID 27114034 DOI: 10.1016/J.Cell.2016.04.010 |
0.35 |
|
| 2016 |
Mason RD, Welles HC, Adams C, Chakrabarti BK, Gorman J, Zhou T, Nguyen R, O'Dell S, Lusvarghi S, Bewley CA, Li H, Shaw GM, Sheng Z, Shapiro L, Wyatt R, et al. Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. Plos Pathogens. 12: e1005537. PMID 27064278 DOI: 10.1371/Journal.Ppat.1005537 |
0.359 |
|
| 2016 |
Dogo-Isonagie C, Lee SL, Lohith K, Liu H, Mandadapu SR, Lusvarghi S, O'Connor RD, Bewley CA. Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry. Bioorganic & Medicinal Chemistry. PMID 26968647 DOI: 10.1016/J.Bmc.2016.02.044 |
0.403 |
|
| 2016 |
Sabovljević MS, Vujičić M, Wang X, Garraffo HM, Bewley CA, Sabovljević A. Production of the macrocyclic bis-bibenzyls in axenically farmed and wild liverwort Marchantia polymorpha L. subsp. ruderalis Bischl. et Boisselier Plant Biosystems. 1-5. DOI: 10.1080/11263504.2016.1179692 |
0.346 |
|
| 2015 |
Sastry M, Bewley CA, Kwong PD. Effective isotope labeling of proteins in a mammalian expression system. Methods in Enzymology. 565: 289-307. PMID 26577736 DOI: 10.1016/Bs.Mie.2015.09.021 |
0.332 |
|
| 2015 |
Lusvarghi S, Ghirlando R, Wong CH, Bewley CA. Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function. Angewandte Chemie (International Ed. in English). 54: 5603-8. PMID 25776945 DOI: 10.1002/Anie.201500157 |
0.332 |
|
| 2015 |
Acharya P, Lusvarghi S, Bewley CA, Kwong PD. HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth. Expert Opinion On Therapeutic Targets. 19: 765-83. PMID 25724219 DOI: 10.1517/14728222.2015.1010513 |
0.302 |
|
| 2014 |
Louis JM, Aniana A, Lohith K, Sayer JM, Roche J, Bewley CA, Clore GM. Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations. Plos One. 9: e104683. PMID 25105806 DOI: 10.1371/Journal.Pone.0104683 |
0.346 |
|
| 2014 |
Mason R, Adams C, Bewley C, Mascola J, Roederer M. Potent SIV-specific Antibodies Targeting the Cyanovirin Binding Site Aids Research and Human Retroviruses. 30: A211-A212. DOI: 10.1089/Aid.2014.5457C.Abstract |
0.385 |
|
| 2013 |
Kachko A, Loesgen S, Shahzad-Ul-Hussan S, Tan W, Zubkova I, Takeda K, Wells F, Rubin S, Bewley CA, Major ME. Inhibition of hepatitis C virus by the cyanobacterial protein Microcystis viridis lectin: mechanistic differences between the high-mannose specific lectins MVL, CV-N, and GNA. Molecular Pharmaceutics. 10: 4590-602. PMID 24152340 DOI: 10.1021/Mp400399B |
0.301 |
|
| 2013 |
Keffer JL, Huecas S, Hammill JT, Wipf P, Andreu JM, Bewley CA. Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria. Bioorganic & Medicinal Chemistry. 21: 5673-8. PMID 23932448 DOI: 10.1016/J.Bmc.2013.07.033 |
0.72 |
|
| 2013 |
Pancera M, Shahzad-Ul-Hussan S, Doria-Rose NA, McLellan JS, Bailer RT, Dai K, Loesgen S, Louder MK, Staupe RP, Yang Y, Zhang B, Parks R, Eudailey J, Lloyd KE, Blinn J, ... Bewley CA, et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nature Structural & Molecular Biology. 20: 804-13. PMID 23708607 DOI: 10.1038/Nsmb.2600 |
0.348 |
|
| 2013 |
Emileh A, Tuzer F, Yeh H, Umashankara M, Moreira DR, Lalonde JM, Bewley CA, Abrams CF, Chaiken IM. A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption. Biochemistry. 52: 2245-61. PMID 23470147 DOI: 10.1021/Bi400166B |
0.367 |
|
| 2012 |
Sastry M, Bewley CA, Kwong PD. Mammalian expression of isotopically labeled proteins for NMR spectroscopy. Advances in Experimental Medicine and Biology. 992: 197-211. PMID 23076586 DOI: 10.1007/978-94-007-4954-2_11 |
0.338 |
|
| 2012 |
Driessen NN, Boshoff HI, Maaskant JJ, Gilissen SA, Vink S, van der Sar AM, Vandenbroucke-Grauls CM, Bewley CA, Appelmelk BJ, Geurtsen J. Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 189: 3585-92. PMID 22942435 DOI: 10.4049/Jimmunol.1102408 |
0.349 |
|
| 2012 |
Keffer JL, Hammill JT, Lloyd JR, Plaza A, Wipf P, Bewley CA. Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments. Marine Drugs. 10: 1103-25. PMID 22822360 DOI: 10.3390/Md10051103 |
0.726 |
|
| 2012 |
Shahzad-ul-Hussan S, Ghirlando R, Dogo-Isonagie CI, Igarashi Y, Balzarini J, Bewley CA. Characterization and carbohydrate specificity of pradimicin S. Journal of the American Chemical Society. 134: 12346-9. PMID 22788706 DOI: 10.1021/Ja303860M |
0.369 |
|
| 2012 |
Kwon YD, Finzi A, Wu X, Dogo-Isonagie C, Lee LK, Moore LR, Schmidt SD, Stuckey J, Yang Y, Zhou T, Zhu J, Vicic DA, Debnath AK, Shapiro L, Bewley CA, et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proceedings of the National Academy of Sciences of the United States of America. 109: 5663-8. PMID 22451932 DOI: 10.1073/Pnas.1112391109 |
0.328 |
|
| 2012 |
Dogo-Isonagie C, Lam S, Gustchina E, Acharya P, Yang Y, Shahzad-ul-Hussan S, Clore GM, Kwong PD, Bewley CA. Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1. The Journal of Biological Chemistry. 287: 15076-86. PMID 22403408 DOI: 10.1074/Jbc.M111.332361 |
0.395 |
|
| 2012 |
Cheruku P, Plaza A, Lauro G, Keffer J, Lloyd JR, Bifulco G, Bewley CA. Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor. Journal of Medicinal Chemistry. 55: 735-42. PMID 22168797 DOI: 10.1021/Jm201238P |
0.731 |
|
| 2012 |
Hansman GS, Shahzad-Ul-Hussan S, McLellan JS, Chuang GY, Georgiev I, Shimoike T, Katayama K, Bewley CA, Kwong PD. Structural basis for norovirus inhibition and fucose mimicry by citrate. Journal of Virology. 86: 284-92. PMID 22031945 DOI: 10.1128/Jvi.05909-11 |
0.333 |
|
| 2012 |
Pancera M, McLellan J, Shahzad-ul-Hussan S, Doria-Rose N, Zhang B, Yang Y, Burton, Koff W, Bewley C, Kwong P. Structural comparison of somatically related PG9 and PG16 in complex with their epitope reveals differences in glycan recognition Retrovirology. 9: 74. DOI: 10.1186/1742-4690-9-S2-P74 |
0.347 |
|
| 2012 |
Sastry M, Xu L, Bhattacharya S, Nabel G, Bewley C, Kwong P. NMR spectroscopy of HIV-1 gp120 outer domain Retrovirology. 9: 20. DOI: 10.1186/1742-4690-9-S2-P20 |
0.312 |
|
| 2012 |
Perera HD, Keffer J, Bewley C. The Mode of Action of FtsZ Inhibitors Biophysical Journal. 102: 64a. DOI: 10.1016/J.Bpj.2011.11.380 |
0.727 |
|
| 2012 |
Emileh A, Tuzer F, Moreira DR, LaLonde JM, Bewley CA, Chaiken IM, Abrams CF. A Molecular Dynamics Simulation of Peptide-Triazole HIV Entry Inhibitor Binding to gp120 Hydrophobic Core Biophysical Journal. 102: 621a. DOI: 10.1016/J.Bpj.2011.11.3383 |
0.376 |
|
| 2011 |
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Bewley CA, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696 |
0.308 |
|
| 2011 |
Acharya P, Dogo-Isonagie C, LaLonde JM, Lam SN, Leslie GJ, Louder MK, Frye LL, Debnath AK, Greenwood JR, Luongo TS, Martin L, Watts KS, Hoxie JA, Mascola JR, Bewley CA, et al. Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry. Acs Chemical Biology. 6: 1069-77. PMID 21793507 DOI: 10.1021/Cb200068B |
0.404 |
|
| 2011 |
Sastry M, Xu L, Georgiev IS, Bewley CA, Nabel GJ, Kwong PD. Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy. Journal of Biomolecular Nmr. 50: 197-207. PMID 21667299 DOI: 10.1007/S10858-011-9506-4 |
0.369 |
|
| 2011 |
Shahzad-ul-Hussan S, Gustchina E, Ghirlando R, Clore GM, Bewley CA. Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. The Journal of Biological Chemistry. 286: 20788-96. PMID 21471192 DOI: 10.1074/Jbc.M111.232678 |
0.415 |
|
| 2011 |
Gutierrez-Lugo MT, Bewley CA. Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 2480-3. PMID 21392992 DOI: 10.1016/J.Bmcl.2011.02.042 |
0.342 |
|
| 2011 |
Lu Z, Van Wagoner RM, Harper MK, Baker HL, Hooper JN, Bewley CA, Ireland CM. Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosa. Journal of Natural Products. 74: 185-93. PMID 21280591 DOI: 10.1021/Np100613P |
0.403 |
|
| 2010 |
Gustchina E, Li M, Louis JM, Anderson DE, Lloyd J, Frisch C, Bewley CA, Gustchina A, Wlodawer A, Clore GM. Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41. Plos Pathogens. 6: e1001182. PMID 21085615 DOI: 10.1371/Journal.Ppat.1001182 |
0.351 |
|
| 2010 |
Metaferia BB, Rittler M, Gheeya JS, Lee A, Hempel H, Plaza A, Stetler-Stevenson WG, Bewley CA, Khan J. Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry. Bioorganic & Medicinal Chemistry Letters. 20: 7337-40. PMID 21050757 DOI: 10.1016/J.Bmcl.2010.10.064 |
0.317 |
|
| 2010 |
Cheruku P, Keffer JL, Dogo-Isonagie C, Bewley CA. Motualevic acids and analogs: synthesis and antimicrobial structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 20: 4108-11. PMID 20538459 DOI: 10.1016/J.Bmcl.2010.05.073 |
0.724 |
|
| 2010 |
Plaza A, Keffer JL, Bifulco G, Lloyd JR, Bewley CA. Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ. Journal of the American Chemical Society. 132: 9069-77. PMID 20536175 DOI: 10.1021/Ja102100H |
0.744 |
|
| 2010 |
Plaza A, Bifulco G, Masullo M, Lloyd JR, Keffer JL, Colin PL, Hooper JN, Bell LJ, Bewley CA. Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species. The Journal of Organic Chemistry. 75: 4344-55. PMID 20402515 DOI: 10.1021/Jo100076G |
0.738 |
|
| 2010 |
Plaza A, Keffer JL, Lloyd JR, Colin PL, Bewley CA. Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei. Journal of Natural Products. 73: 485-8. PMID 20078073 DOI: 10.1021/Np900728X |
0.726 |
|
| 2009 |
Shahzad-ul-Hussan S, Cai M, Bewley CA. Unprecedented glycosidase activity at a lectin carbohydrate-binding site exemplified by the cyanobacterial lectin MVL. Journal of the American Chemical Society. 131: 16500-8. PMID 19856962 DOI: 10.1021/Ja905929C |
0.399 |
|
| 2009 |
Gustchina E, Louis JM, Frisch C, Ylera F, Lechner A, Bewley CA, Clore GM. Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth. Virology. 393: 112-9. PMID 19695655 DOI: 10.1016/J.Virol.2009.07.019 |
0.376 |
|
| 2009 |
Gutierrez-Lugo MT, Baker H, Shiloach J, Boshoff H, Bewley CA. Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening. Journal of Biomolecular Screening. 14: 643-52. PMID 19525487 DOI: 10.1177/1087057109335743 |
0.342 |
|
| 2009 |
Keffer JL, Plaza A, Bewley CA. Motualevic acids A-F, antimicrobial acids from the sponge Siliquariaspongia sp. Organic Letters. 11: 1087-90. PMID 19191563 DOI: 10.1021/Ol802890B |
0.719 |
|
| 2009 |
Plaza A, Bifulco G, Keffer JL, Lloyd JR, Baker HL, Bewley CA. Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry. The Journal of Organic Chemistry. 74: 504-12. PMID 19072692 DOI: 10.1021/Jo802232U |
0.743 |
|
| 2008 |
Lam SN, Acharya P, Wyatt R, Kwong PD, Bewley CA. Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry. Bioorganic & Medicinal Chemistry. 16: 10113-20. PMID 18952441 DOI: 10.1016/J.Bmc.2008.10.005 |
0.393 |
|
| 2008 |
Gustchina E, Bewley CA, Clore GM. Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41. Journal of Virology. 82: 10032-41. PMID 18667502 DOI: 10.1128/Jvi.01050-08 |
0.365 |
|
| 2008 |
Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, et al. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics. Virology. 377: 170-83. PMID 18499210 DOI: 10.1016/J.Virol.2008.04.005 |
0.369 |
|
| 2008 |
Plaza A, Baker HL, Bewley CA. Mirabalin, [corrected] an antitumor macrolide lactam from the marine sponge Siliquariaspongia mirabilis. Journal of Natural Products. 71: 473-7. PMID 18271553 DOI: 10.1021/Np070603P |
0.338 |
|
| 2007 |
Metaferia BB, Fetterolf BJ, Shazad-Ul-Hussan S, Moravec M, Smith JA, Ray S, Gutierrez-Lugo MT, Bewley CA. Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase. Journal of Medicinal Chemistry. 50: 6326-36. PMID 18020307 DOI: 10.1021/Jm070669H |
0.338 |
|
| 2007 |
Plaza A, Gustchina E, Baker HL, Kelly M, Bewley CA. Mirabamides A-D, depsipeptides from the sponge Siliquariaspongia mirabilis that inhibit HIV-1 fusion. Journal of Natural Products. 70: 1753-60. PMID 17963357 DOI: 10.1021/Np070306K |
0.432 |
|
| 2007 |
Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (New York, N.Y.). 317: 1930-4. PMID 17901336 DOI: 10.1126/Science.1145373 |
0.36 |
|
| 2007 |
Gustchina E, Louis JM, Lam SN, Bewley CA, Clore GM. A monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains. Journal of Virology. 81: 12946-53. PMID 17898046 DOI: 10.1128/Jvi.01260-07 |
0.387 |
|
| 2007 |
Metaferia BB, Ray S, Smith JA, Bewley CA. Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 17: 444-7. PMID 17084627 DOI: 10.1016/J.Bmcl.2006.10.031 |
0.329 |
|
| 2006 |
Gustchina E, Louis JM, Bewley CA, Clore GM. Synergistic Inhibition of HIV-1 Envelope-Mediated Membrane Fusion by Inhibitors Targeting the N and C-Terminal Heptad Repeats of gp41 Journal of Molecular Biology. 364: 283-289. PMID 17010381 DOI: 10.1016/J.Jmb.2006.09.017 |
0.37 |
|
| 2006 |
Mares J, Müller JU, Skirgailiene A, Neumoin A, Bewley CA, Schmidt RR, Zerbe O. A model for cell-surface-exposed carbohydrate moieties suitable for structural studies by NMR spectroscopy. Chembiochem : a European Journal of Chemical Biology. 7: 1764-73. PMID 16952190 DOI: 10.1002/Cbic.200600219 |
0.371 |
|
| 2006 |
Plaza A, Bewley CA. Largamides A-H, unusual cyclic peptides from the marine cyanobacterium Oscillatoria sp. The Journal of Organic Chemistry. 71: 6898-907. PMID 16930043 DOI: 10.1021/Jo061044E |
0.406 |
|
| 2006 |
Gutierrez-Lugo MT, Newton GL, Fahey RC, Bewley CA. Cloning, expression and rapid purification of active recombinant mycothiol ligase as B1 immunoglobulin binding domain of streptococcal protein G, glutathione-S-transferase and maltose binding protein fusion proteins in Mycobacterium smegmatis. Protein Expression and Purification. 50: 128-36. PMID 16908186 DOI: 10.1016/J.Pep.2006.07.005 |
0.336 |
|
| 2005 |
Louis JM, Bewley CA, Gustchina E, Aniana A, Clore GM. Characterization and HIV-1 fusion inhibitory properties of monoclonal fabs obtained from a human non-immune phage library selected against diverse epitopes of the ectodomain of HIV-1 gp41 Journal of Molecular Biology. 353: 945-951. PMID 16216270 DOI: 10.1016/J.Jmb.2005.09.044 |
0.366 |
|
| 2005 |
Dimitrov AS, Louis JM, Bewley CA, Clore GM, Blumenthal R. Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation Biochemistry. 44: 12471-12479. PMID 16156659 DOI: 10.1021/Bi051092D |
0.389 |
|
| 2005 |
Williams DC, Lee JY, Cai M, Bewley CA, Clore GM. Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to man3GlcNAc2: Structural basis for specificity and high-affinity binding to the core pentasaccharide from N-linked oligomannoside Journal of Biological Chemistry. 280: 29269-29276. PMID 15937331 DOI: 10.1074/Jbc.M504642200 |
0.413 |
|
| 2005 |
Gustchina E, Hummer G, Bewley CA, Clore GM. Differential inhibition of HIV-1 and SIV envelope-mediated cell fusion by C34 peptides derived from the C-terminal heptad repeat of gp41 from diverse strains of HIV-1, HIV-2, and SIV Journal of Medicinal Chemistry. 48: 3036-3044. PMID 15828842 DOI: 10.1021/Jm049026H |
0.386 |
|
| 2004 |
Bewley CA, Ray S, Cohen F, Collins SK, Overman LE. Inhibition of HIV-1 envelope-mediated fusion by synthetic batzelladine analogues. Journal of Natural Products. 67: 1319-24. PMID 15332849 DOI: 10.1021/Np049958O |
0.418 |
|
| 2004 |
Gallo SA, Clore GM, Louis JM, Bewley CA, Blumenthal R. Temperature-dependent intermediates in HIV-1 envelope glycoprotein-mediated fusion revealed by inhibitors that target N- and C-terminal helical regions of HIV-1 gp41 Biochemistry. 43: 8230-8233. PMID 15209519 DOI: 10.1021/Bi049957V |
0.37 |
|
| 2004 |
Fetterolf B, Bewley CA. Synthesis of a bromotyrosine-derived natural product inhibitor of mycothiol-S-conjugate amidase. Bioorganic & Medicinal Chemistry Letters. 14: 3785-8. PMID 15203162 DOI: 10.1016/J.Bmcl.2004.04.095 |
0.355 |
|
| 2004 |
Bewley CA, Cai M, Ray S, Ghirlando R, Yamaguchi M, Muramoto K. New carbohydrate specificity and HIV-1 fusion blocking activity of the cyanobacterial protein MVL: NMR, ITC and sedimentation equilibrium studies. Journal of Molecular Biology. 339: 901-14. PMID 15165858 DOI: 10.1016/J.Jmb.2004.04.019 |
0.426 |
|
| 2003 |
Chang L, Whittaker NF, Bewley CA. Crambescidin 826 and dehydrocrambine A: new polycyclic guanidine alkaloids from the marine sponge Monanchora sp. that inhibit HIV-1 fusion. Journal of Natural Products. 66: 1490-4. PMID 14640525 DOI: 10.1021/Np030256T |
0.385 |
|
| 2003 |
Mahadevan J, Nicholas GM, Bewley CA. Solution conformations of mycothiol bimane, 1-D-GlcNAc-alpha-(1 --> 1)-D-myo-Ins and 1-D-GlcNAc-alpha-(1 --> 1)-L-myo-Ins. The Journal of Organic Chemistry. 68: 3380-6. PMID 12713335 DOI: 10.1021/Jo026872W |
0.304 |
|
| 2003 |
Louis JM, Nesheiwat I, Chang L, Clore GM, Bewley CA. Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion. The Journal of Biological Chemistry. 278: 20278-85. PMID 12654905 DOI: 10.1074/Jbc.M301627200 |
0.372 |
|
| 2003 |
Nicholas GM, Eckman LL, Newton GL, Fahey RC, Ray S, Bewley CA. Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors. Bioorganic & Medicinal Chemistry. 11: 601-8. PMID 12538025 DOI: 10.1016/S0968-0896(02)00345-0 |
0.374 |
|
| 2002 |
Knapp S, Gonzalez S, Myers DS, Eckman LL, Bewley CA. Shortcut to mycothiol analogues. Organic Letters. 4: 4337-9. PMID 12443092 DOI: 10.1021/Ol0269796 |
0.317 |
|
| 2002 |
Bewley CA, Kiyonaka S, Hamachi I. Site-specific discrimination by cyanovirin-N for α-linked trisaccharides comprising the three arms of Man8 and Man9 Journal of Molecular Biology. 322: 881-889. PMID 12270721 DOI: 10.1016/S0022-2836(02)00842-2 |
0.376 |
|
| 2002 |
Nicholas GM, Eckman LL, Ray S, Hughes RO, Pfefferkorn JA, Barluenga S, Nicolaou KC, Bewley CA. Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorganic & Medicinal Chemistry Letters. 12: 2487-90. PMID 12161164 DOI: 10.1016/S0960-894X(02)00385-2 |
0.358 |
|
| 2002 |
Chang LC, Bewley CA. Potent inhibition of HIV-1 fusion by cyanovirin-N requires only a single high affinity carbohydrate binding site: characterization of low affinity carbohydrate binding site knockout mutants. Journal of Molecular Biology. 318: 1-8. PMID 12054763 DOI: 10.1016/S0022-2836(02)00045-1 |
0.348 |
|
| 2002 |
Chang LC, Otero-Quintero S, Hooper JN, Bewley CA. Batzelline D and isobatzelline E from the indopacific sponge Zyzzya fuliginosa. Journal of Natural Products. 65: 776-8. PMID 12027767 DOI: 10.1021/Np010581L |
0.38 |
|
| 2002 |
Nicholas GM, Kovác P, Bewley CA. Total synthesis and proof of structure of mycothiol bimane. Journal of the American Chemical Society. 124: 3492-3. PMID 11929223 DOI: 10.1021/Ja017891A |
0.323 |
|
| 2002 |
Kelley BS, Chang LC, Bewley CA. Engineering an obligate domain-swapped dimer of cyanovirin-N with enhanced anti-HIV activity. Journal of the American Chemical Society. 124: 3210-1. PMID 11916396 DOI: 10.1021/Ja025537M |
0.379 |
|
| 2002 |
Bewley CA, Louis JM, Ghirlando R, Clore GM. Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41. The Journal of Biological Chemistry. 277: 14238-45. PMID 11859089 DOI: 10.1074/Jbc.M201453200 |
0.4 |
|
| 2001 |
Bewley CA. Solution structure of a cyanovirin-N:Manα1-2Manα complex: Structural basis for high-affinity carbohydrate-mediated binding to gp120 Structure. 9: 931-940. PMID 11591348 DOI: 10.1016/S0969-2126(01)00653-0 |
0.369 |
|
| 2001 |
Bewley CA, Otero-Quintero S. The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man8 D1D3 and Man9 with nanomolar affinity: Implications for binding to the HIV envelope protein gp120 Journal of the American Chemical Society. 123: 3892-3902. PMID 11457139 DOI: 10.1021/Ja004040E |
0.361 |
|
| 2001 |
Bewley CA. Rapid validation of the overall structure of an internal domain-swapped mutant of the anti-HIV protein cyanovirin-N using residual dipolar couplings. Journal of the American Chemical Society. 123: 1014-5. PMID 11456652 DOI: 10.1021/Ja005714O |
0.348 |
|
| 2001 |
Louis JM, Bewley CA, Clore GM. Design and Properties of NCCG-gp41, a Chimeric gp41 Molecule with Nanomolar HIV Fusion Inhibitory Activity Journal of Biological Chemistry. 276: 29485-29489. PMID 11418583 DOI: 10.1074/Jbc.C100317200 |
0.361 |
|
| 2001 |
Nicholas GM, Newton GL, Fahey RC, Bewley CA. Novel bromotyrosine alkaloids: inhibitors of mycothiol S-conjugate amidase. Organic Letters. 3: 1543-5. PMID 11388862 DOI: 10.1021/Ol015845+ |
0.37 |
|
| 2001 |
Chee Chang L, Otero-Quintero S, Nicholas GM, Bewley CA. Phyllolactones A-E: New bishomoscalarane sesterterpenes from the marine sponge Phyllospongia lamellosa Tetrahedron. 57: 5731-5738. DOI: 10.1016/S0040-4020(01)00515-4 |
0.363 |
|
| 1999 |
Yang F, Bewley CA, Louis JM, Gustafson KR, Boyd MR, Gronenborn AM, Clore GM, Wlodawer A. Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping Journal of Molecular Biology. 288: 403-412. PMID 10329150 DOI: 10.1006/Jmbi.1999.2693 |
0.318 |
|
| 1998 |
Bewley CA, Gustafson KR, Boyd MR, Covell DG, Bax A, Clore GM, Gronenborn AM. Solution structure of cyanovirin-N, a potent HIV-inactivating protein Nature Structural Biology. 5: 571-578. PMID 9665171 DOI: 10.1038/828 |
0.368 |
|
| 1998 |
Schmidt EW, Bewley CA, Faulkner DJ. Theopalauamide, a Bicyclic Glycopeptide from Filamentous Bacterial Symbionts of the Lithistid Sponge Theonella swinhoei from Palau and Mozambique Journal of Organic Chemistry. 63: 1254-1258. DOI: 10.1021/Jo9718455 |
0.345 |
|
| 1997 |
Huth JR, Bewley CA, Jackson BM, Hinnebusch AG, Clore GM, Gronenborn AM. Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR Protein Science. 6: 2359-2364. PMID 9385638 DOI: 10.1002/Pro.5560061109 |
0.332 |
|
| 1996 |
Bewley CA, Holland ND, Faulkner DJ. Two classes of metabolites from Theonella swinhoei are localized in distinct populations of bacterial symbionts. Experientia. 52: 716-22. PMID 8698116 DOI: 10.1007/Bf01925581 |
0.313 |
|
| 1996 |
Bewley CA, He H, Williams DH, Faulkner DJ. Aciculitins A-C: Cytotoxic and antifungal cyclic peptides from the lithistid sponge Aciculites orientalis Journal of the American Chemical Society. 118: 4314-4321. DOI: 10.1021/Ja953628W |
0.356 |
|
| 1995 |
Newton GL, Bewley CA, Dwyer TJ, Horn R, Aharonowitz Y, Cohen G, Davies J, Faulkner DJ, Fahey RC. The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol. European Journal of Biochemistry / Febs. 230: 821-5. PMID 7607257 DOI: 10.1111/J.1432-1033.1995.0821H.X |
0.38 |
|
| 1994 |
Bewley CA, Faulkner DJ. Theonegramide, an antifungal glycopeptide from the Philippine lithistid sponge Theonella swinhoei Journal of Organic Chemistry. 59: 4849-4852. DOI: 10.1021/Jo00096A028 |
0.33 |
|
| 1994 |
Bewley CA, Debitus C, Faulkner DJ. Microsclerodermins A and B. Antifungal cyclic peptides from the lithistid sponge Microscleroderma sp Journal of the American Chemical Society. 116: 7631-7636. DOI: 10.1021/Ja00096A020 |
0.358 |
|
| Show low-probability matches. |